# Algodistrofia

> Página oficial: https://raras.org/doenca/algodistrofia
> Fonte: Raras.org — Banco de Dados de Doenças Raras em Português (CC BY-NC-SA 4.0)
> Última atualização: 2026-05-07

## Identificadores

- **ORPHA**: 99995 — https://www.orpha.net/en/disease/detail/99995
- **CID-10**: G90.5
- **OMIM**: 604335 — https://omim.org/entry/604335

## Descrição clínica

A Algodistrofia, também conhecida como Síndrome Dolorosa Regional Complexa tipo 1, é uma condição crônica caracterizada por dor intensa, inchaço e alterações na pele e temperatura de um membro, geralmente após uma lesão ou fratura. Os sintomas podem incluir sensibilidade extrema ao toque, rigidez articular e alterações na coloração e textura da pele afetada.

## Epidemiologia e herança

- **Prevalência**: 1-5 / 10 000

## Ensaios clínicos ativos (10)

- **NCT07210515** [RECRUITING]: Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE) — https://clinicaltrials.gov/study/NCT07210515
- **NCT07473635** [RECRUITING]: Perineural Incobotulinumtoxin-A for Complex Regional Pain Syndrome - An Open-label Feasibility Study — https://clinicaltrials.gov/study/NCT07473635
- **NCT06523361** [RECRUITING]: Contribution of Immersive Virtual Reality to a Standardized Rehabilitation Program for Upper Limb Chronic Pain: A Single-Case Experimental Design Study — https://clinicaltrials.gov/study/NCT06523361
- **NCT05922618** [RECRUITING]: Pulsed Electromagnetic Fields (PEMFS) in Complex Regional Pain Syndrome Type i (CRPS-I) of the Foot (PeCFoA) — https://clinicaltrials.gov/study/NCT05922618
- **NCT05052736** [RECRUITING]: Non Invasive Neurostimulation Technology for the Treatment of Type I Complex Regional Pain Syndrome (CRPS I) — https://clinicaltrials.gov/study/NCT05052736
- **NCT04767646** [RECRUITING]: Evaluation of the Relationship Between the Duration of the Evolution of the Complex Regional Pain Syndrome Type 1 (CRPS 1) and Effectiveness of the Continuous Peripheral Nerve Block (CPNB) Associated With an Intensive Rehabilitation Program — https://clinicaltrials.gov/study/NCT04767646
- **NCT06769373** [RECRUITING]: The Effects of Whirlpool and Contrast Bath in Patients with Complex Regional Pain Syndrome After Distal Radius Fracture — https://clinicaltrials.gov/study/NCT06769373
- **NCT06306157** [ENROLLING_BY_INVITATION]: Low Dose Naltrexone Therapy for Complex Regional Pain Syndrome — https://clinicaltrials.gov/study/NCT06306157
- **NCT07147140** [ACTIVE_NOT_RECRUITING]: Physiological Parameters in CRPS Patients Treated With Dorsal Root Ganglion Stimulation — https://clinicaltrials.gov/study/NCT07147140
- **NCT06978608** [NOT_YET_RECRUITING]: Ultrasound and Somatosensory Median Nerve Evaluation in CRPS I — https://clinicaltrials.gov/study/NCT06978608

## Importante

O Raras **não diagnostica e não prescreve**. Esta página é educativa e informativa.
Pacientes devem consultar profissionais de saúde qualificados para decisões clínicas.

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**Citação sugerida**: Raras.org — Algodistrofia. Disponível em: https://raras.org/doenca/algodistrofia
**Formato HTML**: https://raras.org/doenca/algodistrofia
**Formato RDF/Turtle**: https://raras.org/api/rdf?orpha=99995