# Amiloidose localizada primária

> Página oficial: https://raras.org/doenca/amiloidose-localizada-primaria
> Fonte: Raras.org — Banco de Dados de Doenças Raras em Português (CC BY-NC-SA 4.0)
> Última atualização: 2026-05-07

## Identificadores

- **ORPHA**: 314709 — https://www.orpha.net/en/disease/detail/314709
- **CID-10**: E85.4

## Descrição clínica

Primary localized amyloidosis is a form of AL amyloidosis caused by the aggregation of insoluble amyloid fibrils derived from misfolded monoclonal immunoglobulin light chains usually produced by a plasma cell tumor and characterized by localized amyloid deposition with clinical manifestations restricted to the organ involved, most frequently urinary tract (bladder), eye, respiratory tract (larynx, lungs), and skin.

## Epidemiologia e herança


## Ensaios clínicos ativos (5)

- **NCT01164241** [COMPLETED]: Natural History of Severe Allergic Inflammation and Reactions — https://clinicaltrials.gov/study/NCT01164241
- **NCT06065852** [RECRUITING]: National Registry of Rare Kidney Diseases — https://clinicaltrials.gov/study/NCT06065852
- **NCT01677286** [COMPLETED]: Safety and Effect of Doxycycline in Patients With Amyloidosis — https://clinicaltrials.gov/study/NCT01677286
- **NCT03068208** [UNKNOWN]: Efficacy of Methylene Blue Mediated Photodynamic Therapy for Primary Localized Cutaneous Amyloidosis Treatment in Asians — https://clinicaltrials.gov/study/NCT03068208
- **NCT03068156** [UNKNOWN]: Efficacy of 308-nm Excimer Laser for Primary Localized Cutaneous Amyloidosis Treatment in Asians — https://clinicaltrials.gov/study/NCT03068156

## Importante

O Raras **não diagnostica e não prescreve**. Esta página é educativa e informativa.
Pacientes devem consultar profissionais de saúde qualificados para decisões clínicas.

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**Citação sugerida**: Raras.org — Amiloidose localizada primária. Disponível em: https://raras.org/doenca/amiloidose-localizada-primaria
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