# Anemia falciforme

> Página oficial: https://raras.org/doenca/anemia-falciforme
> Fonte: Raras.org — Banco de Dados de Doenças Raras em Português (CC BY-NC-SA 4.0)
> Última atualização: 2026-05-07

## Identificadores

- **ORPHA**: 275752 — https://www.orpha.net/en/disease/detail/275752
- **CID-10**: D57.0
- **OMIM**: none — https://omim.org/entry/none

## Descrição clínica

Doença genética rara que causa deformação dos glóbulos vermelhos em forma de foice, levando a dor intensa, danos a órgãos e anemia crônica.

## Epidemiologia e herança


## Ensaios clínicos ativos (33)

- **NCT03937817** [RECRUITING]: Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants — https://clinicaltrials.gov/study/NCT03937817
- **NCT04774536** [RECRUITING]: Transplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified Hematopoietic Progenitor Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell Disease — https://clinicaltrials.gov/study/NCT04774536
- **NCT06699849** [RECRUITING]: Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis — https://clinicaltrials.gov/study/NCT06699849
- **NCT05170412** [RECRUITING]: Dietary Intake and Dietary Behaviors in Adults With Sickle Cell Disease — https://clinicaltrials.gov/study/NCT05170412
- **NCT07392216** [RECRUITING]: Functional Ovarian Reserve in Sickle Cell Disease — https://clinicaltrials.gov/study/NCT07392216
- **NCT07247188** [RECRUITING]: Study of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease — https://clinicaltrials.gov/study/NCT07247188
- **NCT06016634** [RECRUITING]: Alendronate for Osteonecrosis in Adults With Sickle Cell Disease — https://clinicaltrials.gov/study/NCT06016634
- **NCT07064174** [RECRUITING]: Sickle Cell Kidney Biorepository — https://clinicaltrials.gov/study/NCT07064174
- **NCT06635902** [RECRUITING]: Intravenous L-Citrulline for Vaso-occlusive Pain Episode in Sickle Cell Disease — https://clinicaltrials.gov/study/NCT06635902
- **NCT06975865** [RECRUITING]: The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease — https://clinicaltrials.gov/study/NCT06975865

## Importante

O Raras **não diagnostica e não prescreve**. Esta página é educativa e informativa.
Pacientes devem consultar profissionais de saúde qualificados para decisões clínicas.

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**Citação sugerida**: Raras.org — Anemia falciforme. Disponível em: https://raras.org/doenca/anemia-falciforme
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