# Degeneração marginal Terrien

> Página oficial: https://raras.org/doenca/degeneracao-marginal-terrien
> Fonte: Raras.org — Banco de Dados de Doenças Raras em Português (CC BY-NC-SA 4.0)
> Última atualização: 2026-05-07

## Identificadores

- **ORPHA**: 519410 — https://www.orpha.net/en/disease/detail/519410
- **CID-10**: H18.4

## Descrição clínica

A distinct marginal thinning of the cornea which causes high degree of against-the-rule astigmatism

## Epidemiologia e herança


## Ensaios clínicos ativos (3)

- **NCT07124910** [RECRUITING]: Comparison of Epi-ON Corneal Collagen Crosslinking Performed Using an 18-Minute UVA Exposure vs. a 24-Minute UVA Exposure on Eyes With Ectatic Corneal Diseases — https://clinicaltrials.gov/study/NCT07124910
- **NCT04094090** [RECRUITING]: Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking in Eyes With Corneal Ectasia — https://clinicaltrials.gov/study/NCT04094090
- **NCT04698590** [ACTIVE_NOT_RECRUITING]: Wavefront Guided Scleral Lenses for Keratoconus and Irregular Astigmatism — https://clinicaltrials.gov/study/NCT04698590
- **NCT04667572** [COMPLETED]: Safety & Effectiveness of the PXL-Platinum 330 System for CXL Using Riboflavin Solution — https://clinicaltrials.gov/study/NCT04667572
- **NCT04649177** [COMPLETED]: Pilot Study to Investigate the Feasibility, Reliability and Efficacy of Utilizing OCT to Automate PROSE Fitting — https://clinicaltrials.gov/study/NCT04649177
- **NCT04177082** [COMPLETED]: Safety and Effectiveness of the PXL-Platinum 330 System for CXL Using Riboflavin Solution — https://clinicaltrials.gov/study/NCT04177082
- **NCT03220529** [COMPLETED]: A Study to Test the Potential of Brillouin Microscopy for Biomechanical Properties Measurements in Human Cornea — https://clinicaltrials.gov/study/NCT03220529
- **NCT04401865** [UNKNOWN]: Safety and Effectiveness of the PXL-Platinum 330 System — https://clinicaltrials.gov/study/NCT04401865
- **NCT02444923** [COMPLETED]: Scleral Versus Corneal RGP Contact Lenses in Irregular Cornea Disorders — https://clinicaltrials.gov/study/NCT02444923

## Importante

O Raras **não diagnostica e não prescreve**. Esta página é educativa e informativa.
Pacientes devem consultar profissionais de saúde qualificados para decisões clínicas.

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**Citação sugerida**: Raras.org — Degeneração marginal Terrien. Disponível em: https://raras.org/doenca/degeneracao-marginal-terrien
**Formato HTML**: https://raras.org/doenca/degeneracao-marginal-terrien
**Formato RDF/Turtle**: https://raras.org/api/rdf?orpha=519410