# Nevus de Ota

> Página oficial: https://raras.org/doenca/nevus-de-ota
> Fonte: Raras.org — Banco de Dados de Doenças Raras em Português (CC BY-NC-SA 4.0)
> Última atualização: 2026-05-07

## Identificadores

- **ORPHA**: 263425 — https://www.orpha.net/en/disease/detail/263425
- **CID-10**: D22.3

## Descrição clínica

Nevus of Ota is an oculodermal melanocytosis more commonly found in Asian and African populations, usually present at birth and characterized by a usually unilateral, bluish gray, patchy, speckled pigmentation (that may progressively enlarge and darken) affecting the skin of the face along the distribution of the ophthalmic and maxillary divisions of the trigeminal nerve (periorbital region, temple, forehead, malar area, nose). In 2/3 cases the ipsilateral sclera is affected. Nevus of Ota usually remains stable once adulthood is reached but an increased risk of glaucoma and uveal melanoma may be observed. Extracutaneous lesions may also occur in cornea, retina, tympanum, nasal mucosa, pharynx, palate. Nevus of Ota occurs as solitary conditions but seldom may occur together with the nevus of Ito or nevus spilus.

## Epidemiologia e herança

- **Prevalência**: Unknown
- **Padrão de herança**: Not applicable

## Ensaios clínicos ativos (3)

- **NCT00580736** [COMPLETED]: Optical Clearing of the Skin in Conjunction With Laser Treatments — https://clinicaltrials.gov/study/NCT00580736
- **NCT04481178** [UNKNOWN]: A Retrospective Study on Laser Treatment of Nevus of Ota in Thai Patients — https://clinicaltrials.gov/study/NCT04481178
- **NCT00287001** [COMPLETED]: Effect of Cold Air Cooling on the Incidence of Post Inflammatory Hyperpigmentation Following Laser Treatment — https://clinicaltrials.gov/study/NCT00287001

## Importante

O Raras **não diagnostica e não prescreve**. Esta página é educativa e informativa.
Pacientes devem consultar profissionais de saúde qualificados para decisões clínicas.

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**Citação sugerida**: Raras.org — Nevus de Ota. Disponível em: https://raras.org/doenca/nevus-de-ota
**Formato HTML**: https://raras.org/doenca/nevus-de-ota
**Formato RDF/Turtle**: https://raras.org/api/rdf?orpha=263425