# Síndrome de artéria mesentérica superior

> Página oficial: https://raras.org/doenca/sindrome-de-arteria-mesenterica-superior
> Fonte: Raras.org — Banco de Dados de Doenças Raras em Português (CC BY-NC-SA 4.0)
> Última atualização: 2026-06-02

## Identificadores

- **ORPHA**: 622099 — https://www.orpha.net/en/disease/detail/622099
- **CID-10**: K31.5

## Descrição clínica

Superior mesenteric artery syndrome (SMAS) is a digestive condition that occurs when the duodenum (the first part of the small intestine) is compressed between two arteries (the aorta and the superior mesenteric artery). This compression causes partial or complete blockage of the duodenum. Symptoms vary based on severity, but can be severely debilitating. Symptoms may include abdominal pain, fullness, nausea, vomiting, and/or weight loss. SMAS typically is due toloss of the mesenteric fat pad (fatty tissue that surrounds the superior mesenteric artery). The most common cause is significant weight loss caused by medical disorders, psychological disorders, or surgery. In younger patients, it most commonly occurs after corrective spinal surgery for scoliosis. Delays in diagnosis may result in significant complications. Depending on the cause and severity, treatment options may include addressing the underlying cause, dietary changes (small feedings or a liquid diet), and/or surgery. Symptoms may not resolve completely after treatment.

## Epidemiologia e herança


## Ensaios clínicos ativos (2)

- **NCT07317076** [RECRUITING]: GT Metabolic Magnet System in Adults With Gastrointestinal Disorders — https://clinicaltrials.gov/study/NCT07317076
- **NCT04515251** [RECRUITING]: Ultrasound Evaluation of Superior Mesenteric Artery Measurements in a Healthy Pediatric Population — https://clinicaltrials.gov/study/NCT04515251
- **NCT06970093** [COMPLETED]: Comparison of One Anastomisis Gastric Bypass and Duodeno-Jejunostomy for Treating SMA Syndrome — https://clinicaltrials.gov/study/NCT06970093
- **NCT07115472** [COMPLETED]: Fluoxetine in Refractory Superior Mesenteric Artery Syndrome by Targeting Comorbid Somatic Symptom Disorder — https://clinicaltrials.gov/study/NCT07115472
- **NCT03416647** [COMPLETED]: SMAS: a Prospective Study in a Single Institution — https://clinicaltrials.gov/study/NCT03416647

## Importante

O Raras **não diagnostica e não prescreve**. Esta página é educativa e informativa.
Pacientes devem consultar profissionais de saúde qualificados para decisões clínicas.

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**Citação sugerida**: Raras.org — Síndrome de artéria mesentérica superior. Disponível em: https://raras.org/doenca/sindrome-de-arteria-mesenterica-superior
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