# Teratoma do sistema nervoso central

> Página oficial: https://raras.org/doenca/teratoma-do-sistema-nervoso-central
> Fonte: Raras.org — Banco de Dados de Doenças Raras em Português (CC BY-NC-SA 4.0)
> Última atualização: 2026-05-07

## Identificadores

- **ORPHA**: 252018 — https://www.orpha.net/en/disease/detail/252018
- **CID-10**: D48.7
- **OMIM**: none — https://omim.org/entry/none

## Descrição clínica

Um teratoma maduro ou imaturo que afeta o cérebro e a medula espinhal.

## Epidemiologia e herança


## Sinais e sintomas (8 fenótipos HPO)

- **Calcificação cerebral** — HPO: HP:0002514
- **Polidipsia** — HPO: HP:0001959
- **Nistagmo** — HPO: HP:0000639
- **Hemiparesia** — HPO: HP:0001269
- **Poliúria** — HPO: HP:0000103
- **Morfologia anormal do abdome** — HPO: HP:0001438
- **Teratoma** — HPO: HP:0009792
- **Diplopia** — HPO: HP:0000651

## Ensaios clínicos ativos (16)

- **NCT00788125** [TERMINATED]: Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors — https://clinicaltrials.gov/study/NCT00788125
- **NCT01346267** [COMPLETED]: Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy — https://clinicaltrials.gov/study/NCT01346267
- **NCT00047320** [COMPLETED]: Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors — https://clinicaltrials.gov/study/NCT00047320
- **NCT00238173** [TERMINATED]: Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors — https://clinicaltrials.gov/study/NCT00238173
- **NCT01158300** [COMPLETED]: PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors — https://clinicaltrials.gov/study/NCT01158300
- **NCT01088763** [TERMINATED]: Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia — https://clinicaltrials.gov/study/NCT01088763
- **NCT00003141** [COMPLETED]: Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors — https://clinicaltrials.gov/study/NCT00003141
- **NCT01273090** [COMPLETED]: Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma — https://clinicaltrials.gov/study/NCT01273090
- **NCT00387920** [COMPLETED]: Sunitinib in Treating Young Patients With Refractory Solid Tumors — https://clinicaltrials.gov/study/NCT00387920
- **NCT00929903** [COMPLETED]: Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment — https://clinicaltrials.gov/study/NCT00929903

## Doenças relacionadas (por similaridade fenotípica)

- [Tumor de células germinativas extragonadal](https://raras.org/doenca/tumor-de-celulas-germinativas-extragonadal) — ORPHA:363579 — 8 sintomas em comum
- [Teratoma extragonadal](https://raras.org/doenca/teratoma-extragonadal) — ORPHA:883 — 8 sintomas em comum
- [Tumor de células germinativas não-disgerminoma extragonadal](https://raras.org/doenca/tumor-de-celulas-germinativas-nao-disgerminoma-extragonadal) — ORPHA:99913 — 8 sintomas em comum
- [Síndrome Senior-Loken](https://raras.org/doenca/sindrome-senior-loken) — ORPHA:3156 — 3 sintomas em comum
- [Doença de Alexander](https://raras.org/doenca/doenca-de-alexander) — ORPHA:58 — 3 sintomas em comum
- [Síndrome Gitelman](https://raras.org/doenca/sindrome-gitelman) — ORPHA:358 — 3 sintomas em comum
- [Calcinose tumoral](https://raras.org/doenca/calcinose-tumoral) — ORPHA:53715 — 3 sintomas em comum
- [Doença do metabolismo do folato](https://raras.org/doenca/doenca-do-metabolismo-do-folato) — ORPHA:285657 — 3 sintomas em comum
- [Cistinose](https://raras.org/doenca/cistinose) — ORPHA:213 — 3 sintomas em comum
- [Síndrome Griscelli](https://raras.org/doenca/sindrome-griscelli) — ORPHA:381 — 3 sintomas em comum

## Importante

O Raras **não diagnostica e não prescreve**. Esta página é educativa e informativa.
Pacientes devem consultar profissionais de saúde qualificados para decisões clínicas.

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**Citação sugerida**: Raras.org — Teratoma do sistema nervoso central. Disponível em: https://raras.org/doenca/teratoma-do-sistema-nervoso-central
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