# Tuberculose do sistema nervoso central

> Página oficial: https://raras.org/doenca/tuberculose-do-sistema-nervoso-central
> Fonte: Raras.org — Banco de Dados de Doenças Raras em Português (CC BY-NC-SA 4.0)
> Última atualização: 2026-05-07

## Identificadores

- **ORPHA**: 641396 — https://www.orpha.net/en/disease/detail/641396
- **CID-10**: A17.0+

## Descrição clínica

A well-circumscribed mass composed of tuberculous granulation tissue that may occur in the cerebral hemispheres, cerebellum, brain stem, or perimeningeal spaces. Multiple lesions are quite common. Management of intracranial manifestations vary with lesion site. Intracranial tuberculomas may be associated with seizures, focal neurologic deficits, and intracranial hypertension. Spinal cord tuberculomas may be associated with localized or radicular pain, weakness, sensory loss, and incontinence. Tuberculomas may arise as opportunistic infections, but also occur in immunocompetent individuals.

## Epidemiologia e herança


## Ensaios clínicos ativos (1)

- **NCT06446245** [RECRUITING]: Adjunctive Doxycycline for Central Nervous System Tuberculosis — https://clinicaltrials.gov/study/NCT06446245
- **NCT06011915** [COMPLETED]: A Retrospective Study of Treatment Patterns and Clinical Outcomes in Patients With Central Nervous System Tuberculosis — https://clinicaltrials.gov/study/NCT06011915
- **NCT04620772** [UNKNOWN]: Cyclophosphamide in the Treatment of Refractory Proliferative Arachnoiditis in CNS Tuberculosis — https://clinicaltrials.gov/study/NCT04620772
- **NCT01589289** [COMPLETED]: Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC — https://clinicaltrials.gov/study/NCT01589289

## Importante

O Raras **não diagnostica e não prescreve**. Esta página é educativa e informativa.
Pacientes devem consultar profissionais de saúde qualificados para decisões clínicas.

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**Citação sugerida**: Raras.org — Tuberculose do sistema nervoso central. Disponível em: https://raras.org/doenca/tuberculose-do-sistema-nervoso-central
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