# Xantoastrocitoma pleomórfico

> Página oficial: https://raras.org/doenca/xantoastrocitoma-pleomorfico
> Fonte: Raras.org — Banco de Dados de Doenças Raras em Português (CC BY-NC-SA 4.0)
> Última atualização: 2026-05-07

## Identificadores

- **ORPHA**: 251607 — https://www.orpha.net/en/disease/detail/251607
- **CID-10**: C71.9

## Descrição clínica

A WHO grade ll astrocytic tumor with a relatively favorable prognosis. It is characterized by pleomorphic and lipidized cells expressing GFAP often surrounded by a reticulin network and eosinophilic granular bodies. It presents in the superficial cerebral hemispheres and involves the meninges. It typically affects children and young adults.

## Epidemiologia e herança

- **Prevalência**: <1 / 1 000 000
- **Padrão de herança**: Not applicable

## Ensaios clínicos ativos (6)

- **NCT04065776** [RECRUITING]: Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma — https://clinicaltrials.gov/study/NCT04065776
- **NCT04541082** [RECRUITING]: Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms — https://clinicaltrials.gov/study/NCT04541082
- **NCT05180825** [RECRUITING]: Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy — https://clinicaltrials.gov/study/NCT05180825
- **NCT03919071** [ACTIVE_NOT_RECRUITING]: Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma — https://clinicaltrials.gov/study/NCT03919071
- **NCT03975829** [ACTIVE_NOT_RECRUITING]: Pediatric Long-Term Follow-up and Rollover Study — https://clinicaltrials.gov/study/NCT03975829
- **NCT07448480** [ACTIVE_NOT_RECRUITING]: Comprehensive Analysis of Chemotherapy and Targeted Therapy Outcomes in Recurrent Malignant Gliomas — https://clinicaltrials.gov/study/NCT07448480
- **NCT03973918** [TERMINATED]: Study of Binimetinib With Encorafenib in Adults With Recurrent BRAF V600-Mutated HGG — https://clinicaltrials.gov/study/NCT03973918
- **NCT01837862** [COMPLETED]: A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas — https://clinicaltrials.gov/study/NCT01837862
- **NCT03434262** [COMPLETED]: SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors — https://clinicaltrials.gov/study/NCT03434262
- **NCT03043391** [COMPLETED]: Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children — https://clinicaltrials.gov/study/NCT03043391

## Importante

O Raras **não diagnostica e não prescreve**. Esta página é educativa e informativa.
Pacientes devem consultar profissionais de saúde qualificados para decisões clínicas.

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**Citação sugerida**: Raras.org — Xantoastrocitoma pleomórfico. Disponível em: https://raras.org/doenca/xantoastrocitoma-pleomorfico
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