The global cancer crisis: a review of growing burden, deepening inequality and initiatives for prevention and early detection.

Monitoring treatment response using an ultra-sensitive ctDNA assay in advanced esophagogastric cancer patients.

Impact of pediatric gastrointestinal disorders on learning and cognitive development in schoolchildren.

Genetic causal association between kidney stones and proton pump inhibitors.

Causal Associations between Gastroesophageal Reflux Disease and Gastroduodenal Ulcer: A Two-sample Mendelian Randomisation Study.

Eosinophilic oesophagitis: pathophysiology, diagnosis, and treatment.

The epidemiology of cubital tunnel syndrome: a UK Biobank case-control study.

Beamion PANTUMOR-1: rationale and design of a Phase II trial of zongertinib in HER2-overexpressed/amplified or HER2-mutant solid tumors.

Targeting APE1-Redox Function Reverses SOX9-mediated Chemoresistance in Esophageal Adenocarcinoma.

Unilateral Multicystic Dysplastic Kidney in a Fetus Associated With Parental Genetic and Environmental Risk Factors: A Case Report.

CYP2C19 genetic polymorphisms and proton pump inhibitor therapy resistance in patients with gastrooesophageal reflux disease: a preliminary observational cohort study.

Genetic evidence links alcohol, coffee, cheese, and anxiety to GERD risk: A Mendelian randomization study.

Gastrointestinal Manifestations in Rubinstein-Taybi Syndrome.

Interstitial cystitis: a phenotype and rare variant exome sequencing study.

Undernutrition and Clinical Deterioration in Children with Cystic Fibrosis: Findings from a Prospective Study.

Cross-trait genetic enrichment between GERD and psychiatric disorders in East Asian populations.

Oral health status and esophageal diseases: Univariate and multivariate Mendelian randomization analyses.

Diagnostic and Therapeutic Challenges Related to HER2 Heterogeneity in Gastric Cancer: Bridging Molecular Pathology and Clinical Decision-Making.

Shared genetic architecture of obesity and gastroesophageal reflux disease.

CYP2C19 genotype-guided dosing of proton pump inhibitors: progress in clinical trials and real-world use.

VSIG10L is a major determinant of esophageal homeostasis and inherited predisposition to Barrett's esophagus.

Gastric cancer attributable to Helicobacter pylori in 2040.

Clinical and genetic characterization of non-optimal triptan response among migraine patients.

MicroRNAs in Esophageal Cancer: Implications for Diagnosis, Progression, Prognosis and Chemoresistance.

Retrograde Cricopharyngeal Dysfunction: An Update of Pathophysiological Mechanisms and Future Directions.

The Bidirectional Relationship Between Gastroesophageal Reflux Disease (GERD) and Asthma in Pediatric and Adult Populations: A Systematic Review.

Gene, genetics and genetic medicines in gastroenterology: Current status and its future.

Associations of phenotypic age acceleration, genetic risk, and lifestyle with chronic digestive diseases: A large-scale longitudinal cohort study.

Is gastroesophageal reflux linked to inflammation-related gestational complications and poor obstetric history?

The role of gene polymorphisms in the occurrence of gastroesophageal reflux disease: A systematic review and meta-analysis of genetic association studies.

Phenotypic Expansion of Autosomal Dominant SREBF1-Related Ichthyosis Follicularis, Atrichia, Photophobia: It Is in Fact the Same Condition as Hereditary Mucoepithelial Dysplasia.

Transformer-based InsightGWAS improves GERD genetic discovery via pretraining on GWAS for major depressive disorder.

Machine learning for screening laryngopharyngeal reflux symptoms in college students: a cross-sectional study.

Circulating tumor DNA informs clinical practice in patients with recurrent/metastatic gastroesophageal cancers.

A machine-learning informed circulating microbial DNA signature for early diagnosis of esophageal adenocarcinoma.

The ratio of omega-6 fatty acids to omega-3 fatty acids mediating the effect of gastroesophageal reflux disease on pancreatic cancer risk: a two-step mediation Mendelian randomisation study.

Non-pharmacological approaches in gastroesophageal reflux disease: Evidence-based dietary and lifestyle interventions.

Claudin 18.2 in cancer research and treatment: a pathologist's perspective.

Ocular Safety Evaluation of Bemarituzumab in FGFR2b-Overexpressing Gastroesophageal Adenocarcinoma: A 42-Week Follow-Up Study.

Evidence for acid-sensing ion channel 3 (ASIC3) involvement in cough resulting from aspiration of gastric fluid.

[Immunotherapy of esophageal, GEJ and gastric tumors].

Non-Invasive Biomarkers for Eosinophilic Esophagitis: Latest Developments and Future Directions.

Associations Between Non-Genetic Risk Factors and DNA Methylation Alterations in Barrett's Esophagus and Its Progression to Esophageal Adenocarcinoma.

Association of the microbiome with pre-epithelial barrier impairment in individuals with laryngopharyngeal reflux.

Clonal cell states link gastroesophageal junction tissues with metaplasia and cancer.

Genomic complexity in advanced gastric and esophageal adenocarcinomas: a case report of rare WDR11-AS1-FGFR2 fusions.

NCI 10211: a phase II, single-arm study of berzosertib in combination with irinotecan in patients with advanced TP53 mutant gastroesophageal cancer.

Cross-sectional study on association of autoantibodies and organ involvement in systemic sclerosis patients.

Biomarkers of aspiration in gastroesophageal reflux-related respiratory disease: A scoping review.

Pharmacokinetics and Bioequivalence of Ilaprazole Enteric-Coated Tablets in Healthy Chinese Volunteers: A Two-Sequence, Four-Period, Fully Replicated Crossover Study.

Identification of shared molecular biomarkers and pathogenic mechanisms between gastroesophageal reflux disease and ischemic stroke via integrated machine learning.

The mediating role of dietary habits in the causal relationships between frailty, depression, and gastroesophageal reflux disease.

Relative telomere length and senescence-associated inflammatory cytokines as blood-based prognostic markers in patients with advanced or resectable gastro-oesophageal adenocarcinoma.

Obesity-Associated TRIM15 Promotes the Proliferation of Esophageal Adenocarcinoma Through the YY2/FOXRED1 Axis.

Gene-Diet interaction between FTO rs9939609 and fiber intake in relation to GERD susceptibility.

Gastroesophageal reflux disease and risk of atrial fibrillation/flutter: Implications for heart failure progression.

CLDN18.2 expression in gastroesophageal adenocarcinoma: prevalence, heterogeneity, and prognostic implications in Spanish patients.

Congenital disorder of glycosylation type IIb in an infant with developmental and epileptic encephalopathy.

The relationship between otitis media and gastroesophageal reflux disease: A 2-sample Mendelian randomization analysis.

Genetic evidence linking gastroesophageal reflux disease to chronic kidney disease and kidney failure: a two-step Mendelian randomization study.

Pre-pandemic disease trajectories and genetic insights into long COVID susceptibility.

Monitoring and Assessment of Circulating Tumor DNA in Cancers Using Ultrarapid Sensitivity as an Innovative Practice.

Mapping Gastroesophageal Reflux Disease and Coronary Artery Disease: A Comprehensive Analysis of Multivariable Mendelian Randomization and Shared Genetic Etiology.

Beamion BCGC-1: phase Ib/II trial of zongertinib for advanced HER2-positive breast or gastroesophageal cancers.

Genomic structural equation modeling identifies shared genetic architecture and novel loci for halitosis.

Pseudodominant Inheritance of Biallelic RFC1 Expansions-Revisiting the 3p22-p24 HSN1B Locus.

Genetically Predicted Gastroesophageal Reflux Disease and Common Thyroid Disorders: A Two-sample Mendelian Randomization Study.

Cystic fibrosis liver disease progression in the era of elexacaftor-tezacaftor-ivacaftor.

Optimizing acid-related disease management: insights into potassium-competitive acid blockers and proton pump inhibitors.

Optimal Cannabinoid-Terpene Combination Ratios Suppress Mutagenicity of Gastric Reflux in Normal and Metaplastic Esophageal Cells.

Genetic determinants of monocyte splicing are enriched for disease susceptibility loci.

Neoadjuvant CTLA-4/PD-(L)1 Blockade Versus Surgery +/- Chemotherapy in Deficient Mismatch Repair/Microsatellite Instability-High Resectable Gastroesophageal Adenocarcinoma: Individual Patient Data Pooled Analysis.

The relationship between insomnia and multiple gastrointestinal disorders: a Mendelian randomization study.

Exploring Potential Hub Genes and Molecular Mechanisms Linking Cardia Carcinoma With Sjögren's Syndrome Based on Comprehensive Bioinformatics Analysis and Machine Learning.

Impact of claudin 18.2 expression on treatment outcomes of first-line immunochemotherapy in patients with HER2-negative, proficient MMR, PD-L1 CPS ⩾1 metastatic gastric/gastroesophageal junction cancer.

Association of CYP2C19 Phenotype on Historical Medication Prescribing for Gastroesophageal Reflux Disease.

Etiology and Pathophysiology of Barrett's Esophagus/Neoplasia.

Refractory Hypophosphatemia Secondary to Tumor-Induced Osteomalacia: Diagnostic Challenges and Successful Management With Burosumab.

Unveiling the genetic overlap and causal links between gastroesophageal reflux disease and asthma.

Ammonia-to-Urea Ratio: A Noninvasive First-Line Tool for Detecting Clinically Significant Portal Hypertension.

Causal relationship between gastroesophageal reflux disease and 7 types of hernias: A bidirectional Mendelian randomization study.

Gastroesophageal reflux disease and risk of laryngeal cancer: A Mendelian randomization study.

Why Every Asthma Patient Tells a Different Story.

Two Cases of Charcot-Marie-Tooth Disease Diagnosed in a 53-Year-Old Mother and a 24-Year-Old Daughter.

Diet, genetic factors, and the risk of gastroesophageal reflux disease, Barrett's esophagus and esophageal adenocarcinoma.

Human Epidermal Growth Factor Receptor 2 [HER-2/neu] Amplification and Microsatellite Stable Status in Gastric and Gastroesophageal Adenocarcinoma: Assessing Frequency and Prognostic Implications at the Cancer Institute of Iran.

Association Between Gastroesophageal Reflux Disease, Barrett's Esophagus and Ear Disorders: A Mendelian Randomization Study.

Causal Relationship Between Cataracts and Gastrointestinal Diseases: A Two-Sample Mendelian Randomization Study.

Increased reflux secondary bile acids are associated with changes to the microbiome and transcriptome in Barrett's esophagus.

Recurrent fexuprazan-induced liver injury following unintentional re-exposure.

The causal relationship between chronic obstructive pulmonary disease and Barrett's esophagitis: A two-sample Mendelian randomization study.

Laparoscopic Treatment of Severe Gastroesophageal Reflux Disease (GERD) in Schaaf-Yang Syndrome: First Report of Toupet Fundoplication.

Mutational Landscape Assessed in Tumor Tissue and Circulating Tumor DNA During Treatment of Patients with HER2/ERBB2-Mutated Solid Tumors.

ALDH18A1 has carcinogenic functions and regulates alternative splicing events of DNA repair-related genes in esophageal carcinoma cells.

Deciphering genetic overlaps between pulmonary tuberculosis and GERD for drug target discovery: A structural bioinformatics perspective.

Causal Relationships Between Modifiable Risk Factors and Gastroesophageal Reflux Disease: A Two-Sample Mendelian Randomization Study.

Targeting DRP1Ser637 Phosphorylation Alleviates Acidic Bile Salt-Induced NF-κB Activation via Mitochondrial Protection.

Low frequency of HER2 expression in colorectal cancer: A Tunisian single-center study.

Key Aspects in the Nutritional Management of Polycystic Liver Disease Patients.

Causal Relationships Between Gastroesophageal Reflux Disease and Myocardial Infarction: Insights From Univariable and Multivariable Mendelian Randomization Analyses.

Management of Dental Demineralization in a Patient with Complex Medical Conditions: A Case Report and Clinical Outcomes.

Gene- and immune-targeted therapy combinations using dual-matched biomarkers for patient selection.

Genetic Analyses Identify Human Serum Metabolites Associated With Risk of Gastroesophageal Reflux Disease: A Mendelian Randomization Study.

Causal relationship between gastroesophageal reflux disease and IgA nephropathy: a Mendelian randomization analysis.

FGFR2b protein overexpression: An emerging biomarker in gastric and gastroesophageal junction adenocarcinoma.

CLDN18.2-targeting antibody-drug conjugate IBI343 in advanced gastric or gastroesophageal junction adenocarcinoma: a phase 1 trial.

Helicobacter pylori Infection and Eradication in Relation to Gastroesophageal Reflux Disease.

Association between antibody-mediated immune responses and gastroesophageal reflux disease: Evidence from genetic studies.

Efficacy of perioperative and neoadjuvant therapies in gastric and gastroesophageal junction adenocarcinoma: a network meta-analysis.

Amprenavir Mitigates Pepsin-Induced Transcriptomic Changes in Normal and Precancerous Esophageal Cells.

DKN-01 and tislelizumab as second-line therapy in DKK1-high gastroesophageal adenocarcinoma: DisTinGuish trial part B.

LncRNA small nucleolar RNA host gene 1 (SNHG1) mediates acidic bile salt-induced EMT via the ULK1-Notch1 axis in Barrett's esophagus.

Assessment of Public Awareness and Prevalence of Asthma Comorbidities in Al-Qunfudhah, Saudi Arabia.

ONO-4578 Plus Nivolumab in Unresectable Advanced or Recurrent Gastric or Gastroesophageal Junction Cancer.

Causal relationship between COVID-19, vaccination, and 20 digestive diseases: a comprehensive two-sample Mendelian randomization study.

Differential Causal Associations of Chronic Gastritis and Ulcerative Colitis with Melanoma Risk: A Mendelian Randomization Study Using Large-Sample GWAS Data.

Association between comorbidity and chronic obstructive pulmonary disease: a systematic review and meta-analysis of Mendelian randomization studies.

Gastric cancer: from biomarkers to functional precision medicine.

Prevalence and management of gastrointestinal complications in Duchenne muscular dystrophy: A retrospective cohort study.

Genetic Evidence of Association Between Gastroesophageal Reflux Disease and Hypertensive Disorders in Pregnancy.

Long-term quality of life after sleeve gastrectomy vs Roux-en-Y Gastric Bypass in patients with severe obesity: Results from the SleeveBypass multicentre randomised controlled trial.

Describing Clinical Characteristics and Treatment Course of Patients with Hereditary Alpha-tryptasemia: A Single-center Study.

A Reflux Linked GATA Factor Fulcrum Dictates Lineage Commitment Through GPRC5B During the Esophageal Dysplastic Transition.

Negative emotions mediate the causal association between GERD and MG: A mediation Mendelian randomization study.

Mood instability and 22 gastrointestinal disorders: investigating the causal relationships and the mediating factors by Mendelian randomization analysis.

Deciphering the dual role of autophagy in gastric cancer and gastroesophageal junction cancer: from tumor suppression to cancer progression.

Zanidatamab plus chemotherapy as first-line treatment for patients with HER2-positive advanced gastro-oesophageal adenocarcinoma: primary results of a multicentre, single-arm, phase 2 study.

X-linked hypohidrotic ectodermal dysplasia associated with gastroesophageal reflux disease.

Inflammatory diseases and risk of lung cancer among individuals who have never smoked.

Commentary: The causal role of gastroesophageal reflux disease in endometriosis: a bidirectional Mendelian randomization study.

Exploration of the potential therapeutic effects and targets of Coriandrum sativum on non-erosive esophagitis based on bioinformatics and molecular dynamics simulation.

Tegoprazan: a novel, highly selective, and potent potassium-competitive acid blocker (P-CAB).

Causal relationships between 91 inflammatory cytokines and gastroesophageal reflux disease, and the mediating role of related metabolites: Evidence from genetics.

Does paired genetic testing improve targeted therapy choices and screening recommendations for patients with upper gastrointestinal cancers and their families? A prospective cohort of 42 patients.

Post-traumatic stress disorder, attention deficit and hyperactivity disorder, and 24 gastrointestinal diseases: Evidence from Mendelian randomization analysis.

Multidimensional Assessment of Psychiatric Adverse Events Related to Proton Pump Inhibitors: A Real-World, Pharmacovigilance Study.

Risk factors associated with hiatal hernia: a retrospective study and two-sample Mendelian randomization.

Zanidatamab monotherapy or combined with chemotherapy in HER2-expressing gastroesophageal adenocarcinoma: a phase 1 trial.

Biomarker-Driven Approach to the Treatment of Metastatic Gastric or Gastroesophageal Adenocarcinoma.

QX-314 inhibits acid-induced esophageal hypersensitivity by regulating TRPV1/NaV1.8 receptor pathway.

Shared genetic architecture of gastroesophageal reflux disease and age related phenotypes.

Diagnostic Management of Pediatric Bronchiectasis: A Literature Review and Clinical Examples.

Causal relationship between gastroesophageal reflux disease and the risk of chronic suppurative otitis media: a mendelian randomization analysis.

Non-Cystic Fibrosis Bronchiectasis in Adults: A Review.

Multiple primary tumors patient developed microsatellite stable gastric cancer after cadonilimab treatment for liver cancer: A case report.

Causal relationship between serum urate and asthma: a Mendelian randomization study.

Exploring the genetic link between gastroesophageal reflux disease and pancreatic cancer: insights from Mendelian randomization.

Assessing the causal association between age at menarche and genetic susceptibility to future gastroesophageal reflux disease risks: A two-sample Mendelian randomization study.

Multi-omics evaluation of peritoneal fluid in gastroesophageal cancer (OMEGCA): protocol for a prospective multicentre cohort study to detect occult peritoneal metastases in patients undergoing curative-intent treatment.

Molecular and Functional Recovery of Esophageal Barrier Integrity After Laparoscopic Anti-reflux Surgery.

Shared and Unique Genetic Links between Neuroticism and Gastrointestinal Tract Diseases.

The Associations of Tobacco, Alcohol, and Coffee Consumption with Upper and Lower Gastrointestinal Disease Risk: A Mendelian Randomization Study.

Study on the common mechanisms of gastroesophageal reflux disease and interstitial lung disease.

Gastroesophageal reflux disease and osteoporosis: A bidirectional Mendelian randomization study.

Decoding the complexity: mechanistic insights into comorbidities in idiopathic pulmonary fibrosis.

Expanding the SIAH1-Associated Phenotypic Spectrum: Insights From Loss-of-Function Variants.

A genome-wide cross-trait analysis characterizes the shared genetic architecture between lung and gastrointestinal diseases.

Molecular Abnormalities and Carcinogenesis in Barrett's Esophagus: Implications for Cancer Treatment and Prevention.

Analysis of Molecular Aspects of Periodontitis as a Risk Factor for Neurodegenerative Diseases: A Single-Center 10-Year Retrospective Cohort Study.

Observational, causal relationship and shared genetic basis between cholelithiasis and gastroesophageal reflux disease: evidence from a cohort study and comprehensive genetic analysis.

Loss of FXR or Bile Acid-dependent Inhibition Accelerate Carcinogenesis of Gastroesophageal Adenocarcinoma.

Association between gestational diabetes mellitus and offspring health: a two-sample mendelian randomization study.

The relationship between amino acids and gastroesophageal reflux disease: evidence from a mendelian randomization analysis combined with a meta-analysis.

Associations between gastroesophageal reflux disease and otolaryngological diseases.

Determinants of Response to Sequential Pembrolizumab with Trastuzumab plus Platinum/5-FU in HER2-Positive Gastric Cancer: A Phase II Chemoimmunotherapy Trial.

PD-1 antibody camrelizumab plus apatinib and SOX as first-line treatment in patients with AFP-producing gastric or gastro-esophageal junction adenocarcinoma (CAP 06): a multi-center, single-arm, phase 2 trial.

First-Line Tislelizumab Plus Chemotherapy for Advanced Gastric Cancer with Programmed Death-Ligand 1 Expression ≥ 1%: A Retrospective Analysis of RATIONALE-305.

Non-coding RNAs in thoracic disease: Barrett's esophagus and esophageal adenocarcinoma.

Mediating effects of gastroesophageal reflux disease and smoking behavior on the relationship between depression and chronic obstructive pulmonary disease: Trans-ethnic Mendelian randomization study.

Gastrointestinal traits, common inflammatory disorders, gallstones, and biliary tract cancer: A network Mendelian randomization study.

Diagnostic Evaluation and Clinical Findings in Children With Persistent Tachypnea of Infancy/Neuroendocrine Cell Hyperplasia of Infancy: A European Multicenter Retrospective Study.

[The role of surgery in preventing esophageal cancer].

Exploring the silent connection: unveiling the intricate relationship between gastroesophageal reflux disease and sleep apnea syndrome.

Sedentary Leisure Behaviour, Physical Activity, and Gastroesophageal Reflux Disease: Evidence From a Mendelian Randomization Analysis.

Interstitial Cystitis: a phenotype and rare variant exome sequencing study: Interstitial Cystitis: a phenotype and exome sequencing study.

The Association Between Gastroesophageal Reflux Disease and Atrial Fibrillation: A Systematic Review and Meta-Analysis.

A novel ingredients recipe derived from Shugan-Hewei Formula targeting chemical carcinogenesis-ROS signaling pathway treated gastroesophageal reflux disease.

Role of Epigenetics in Chronic Lung Disease.

Causal association between gastroesophageal reflux disease and sepsis, and the mediating role of gut bacterial abundance, a Mendelian randomization study.

Untangling immune cell contributions in the progression from GERD to Barrett's esophagus and esophageal cancer: Insights from genetic causal analysis.

Genetic evidence for amlodipine's protective role in gastroesophageal reflux disease: A focus on CACNB2.

Expanding the Gastrointestinal Phenotype of 10p15.3 Microdeletion Syndrome: Refractory Atypical Gastroparesis in an Adult.

Hewei Jiangni granule alleviates visceral hypersensitivity of non-erosive reflux diseasestromal interaction molecule 1/transient receptor potential vanilloid subfamily member 1 pathway.

Multifocal neuromuscular hamartoma with smooth muscle and Schwannian components.

Modifiable factors for irritable bowel syndrome: evidence from Mendelian randomisation approach.

The Dynamic Evolution of Eosinophilic Esophagitis.

Histology of the Upper Gastrointestinal Tract, Morphometry and Lymphocyte Subpopulations of the Duodenal Mucosa: Insights from Healthy Individuals.

How do I treat dMMR/MSI gastro-oesophageal adenocarcinoma in 2025? A position paper from the EORTC-GITCG gastro-esophageal task force.

CAR-macrophage therapy for HER2-overexpressing advanced solid tumors: a phase 1 trial.

Phase 2 study of futibatinib in patients with gastric or gastroesophageal junction cancer harboring FGFR2 amplifications.

Novel risk loci encompassing genes influencing STAT3, GPCR, and oxidative stress signaling are associated with co-morbid GERD and COPD.

Causal relationship between gastroesophageal reflux disease and chronic obstructive respiratory disease: A bidirectional Mendelian randomization study.

Gut microbiota, inflammatory cytokines and gastro-esophageal reflux disease: A Mendelian randomization analysis.

Multi-omics sequencing of gastroesophageal junction adenocarcinoma reveals prognosis-relevant key factors and a novel immunogenomic classification.

Phenotypical Characterization of Gastroenterological and Metabolic Manifestations in Patients With Williams-Beuren Syndrome.

Comprehensive Clinical and Genetic Characterization of a Spanish Cohort of 22 Patients With Bainbridge-Ropers Syndrome.

Dexlansoprazole is an aryl hydrocarbon receptor agonist.

Integrating genetics and transcriptomics to characterize shared mechanisms in digestive diseases and psychiatric disorders.

Association between gastroesophageal reflux disease and venous thromboembolism: A Mendelian randomization study.

Supraglottoplasty outcomes and peri-operative care in congenital laryngomalacia.