In Vivo Imaging of the Innate Immune System in the Pancreas in New-Onset and Long-Standing Type 1 Diabetes.

Sex determines the natural killer cell-mediated immunity against pancreatic cancer.

Type 2 Diabetes From the Perspective of Telomere Biology.

Sex-specific KDM6A-HNF4A-CREBH network controls lipoprotein cholesterol metabolism and atherosclerosis via epigenetic reprograming of hepatocytes.

Rationale for multi-epitope TGFβ vaccination in pancreatic cancer: evidence from immunologic and clinical correlates.

Optic Atrophy in Wolfram Syndrome Type 1: A Retrospective Analysis of Visual Outcomes and Biomarker Correlates.

Targeting PI3Kγ anchoring enhances CFTR membrane localization and modulator efficacy via PKD1.

Synergistic effect of combined hyperthermia and radiotherapy mediated by AQP5 reduction in pancreatic cancer.

Development of CpG-Depleted CFTR Plasmid-Based Nanoparticles for Nonviral Gene Therapy in Lung Cystic Fibrosis Disease.

Diagnostic Value of Next-Generation Sequencing (NGS) and Microarray in Characterizing Tumor Origin: A Challenging and Educational Case.

Efficacy and safety of peptide radionuclide therapy with 177Lu-DOTATATE in Japanese patients with advanced neuroendocrine neoplasm: a multicenter retrospective study (JON2203-N).

Liquid biopsy in pancreatic cancer: current advances, limitations, and future perspectives.

A retrospective analysis of risk-reducing salpingo-oophorectomy performed in women diagnosed with hereditary breast and ovarian cancer at our institution.

Epigenetic regulation in a high-sugar environment (Review).

Crosstalk between KRAS and miRNAs in pancreatic cancer: Opportunities for its diagnosis, prognosis and therapeutic intervention (Review).

ESCRT-Mediated Machinery Directly Drives Cardiac T-Tubule Formation.

Peripheral amylin modulation rebalances brain glycolysis and Tau-Ser214 phosphorylation via cAMP-PKA signaling.

Co-cultivation Serratia marcescens with Trichoderma harzianum for improving production of Huperzine A.

SHR-A1811, a novel HER2-targeting antibody-drug conjugate, in advanced solid tumors (HORIZON-X): a global phase 1 trial.

RARRES1 marks an immune-cold, chemoresistance-associated malignant epithelial subpopulation enriched in pancreatic ductal adenocarcinoma.

Effect of Diosmetin on Gut Microbiota and Serum Metabolites in Acute Pancreatitis Mice: A Metagenomic and Metabolomic Study.

Pancreatic PEComa: Case Report of an Extremely Rare Tumor.

Ganglioside-Mediated Neural-Acinar Crosstalk Facilitates Pancreatic Carcinogenesis via Metaplastic Niche Remodeling.

Predicting recurrence in patients with node-negative perihilar cholangiocarcinoma after an R0 resection.

The role of mesencephalic astrocyte-derived neurotrophic factor in digestive diseases.

KLF5 controls subtype-independent highly interactive enhancers in pancreatic cancer to regulate cell survival.

Factors affecting compliance with pancreas surveillance in patients with familial/genetic risk.

Plasma metabolite association profiles for type 2 diabetes genetic clusters in Finnish men.

Hydroxyl radical footprinting modification reveals an intradomain communication pathway in EFL1 disrupted by a Shwachman-Diamond syndrome-associated mutation.

DNA Origami Nanotechnology in Aging-Related Degenerative Diseases: Current Advances and Future Directions.

Global Collaboration in Cystic Fibrosis: Lessons From the COVID-19 Pandemic for Low- and Middle-Income Countries.

Interkingdom signaling elicited by bacterial extracellular vesicles in human cystic fibrosis airway epithelium and neutrophils.

Evaluation of Metastasis-Associated Lung Adenocarcinoma Transcript 1 (MALAT 1) and H19 in Determining the Diagnosis and Severity of the Disease in Patients with Acute Pancreatitis.

Potential of SERINC2 as a biomarker in tumor prognosis and immunology: analysis from pan-cancer studies.

Gut microbiome in type 2 diabetes: insights from metagenomics, multi-omics, and diet-microbe interactions.

Evaluation of ATP12A and NFKBIZ as potential markers of inflammatory status in cystic fibrosis airway epithelial cells.

The multifaceted roles of the ACSL family in cancer: Metabolic reprogramming, ferroptosis regulation and tumour immune microenvironment remodelling.

Advancements in Sweat Testing Techniques for Cystic Fibrosis: From Classical to Novel Methods.

Targeting MUC16 suppresses malignant progression and chemoresistance in large-duct type intrahepatic cholangiocarcinoma.

Structural insight into the CUB2 domain's role in enteropeptidase-mediated trypsinogen activation.

Nrf3: an emerging player in cancer, inflammation, and cellular homeostasis.

Spatial heterogeneity of antibody-drug conjugate targets in pancreatic ductal adenocarcinoma.

Precision management of medullary thyroid carcinoma: a dynamic framework integrating biomarkers, genotyping, and risk stratification.

Obstructive jaundice induced by postoperative intra-cystic infection with polycystic liver disease: a rare case report and literature review.

The deubiquitinase USP28 promotes esophageal squamous cell carcinoma proliferation by stabilizing ΔNp63 protein.

Unraveling the Link Between Azathioprine and Acute Pancreatitis: Integrating Network Toxicology, Machine Learning, and Mendelian Randomization.

Current State of Clinical Care of People With Cystic Fibrosis.

Building a diagnostic scoring system for high-grade neuroendocrine neoplasms of the pancreas.

Transcription Factors in Type 2 Diabetes: Molecular Mechanisms of Insulin Resistance and β-Cell Dysfunction.

Prevalence of Overweight and Obesity in the Era of CFTR Modulators in Patients with Cystic Fibrosis.

A Diagnostic Dilemma: Concurrent Diagnosis of Cystic Fibrosis and Definitive Kabuki Syndrome Type 1.

Diagnostic Value of miR-21, miR-122, miR-145, and miR-146a in Acute Pancreatitis: Findings from the PASEVO Cohort in Southeastern Romania.

Immune Cell-Specific and Isoform-Selective Regulation of CD44 in Pancreatic Ductal Adenocarcinoma Links Lymph Node Variant Loss and Exosomal CD44 to Clinical Outcome in Pancreatic Ductal Adenocarcinoma.

Targeting Prolyl 3-hydroxylase 1 inhibits pancreatic cancer progression and macrophage immunity.

Epigenetic effects of alcohol consumption on type 2 diabetes.

Deciphering casual association between brain structure and liver cirrhosis: Insights from Mendelian randomization.

Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk.

Clinical signs, management, and survival of 278 dogs diagnosed with insulinoma under primary veterinary care in the United Kingdom.

Roles of ubiquitin‑specific peptidase 22 in cellular fate: From embryonic survival to tissue repair, inflammation and metabolism (Review).

Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.

Super-enhancer-associated miR-1260b coordinates adipogenesis and metabolic programming in human adipose stem cells.

Integrative Bioinformatic Identification and Molecular Docking of Quercetin and Sulforaphane-Associated Prognostic Targets in Pancreatic Adenocarcinoma.

An international consensus on screening and monitoring early-stage type 1 diabetes: A roadmap to European implementation.

Zinc finger protein 598 promotes HIV-1 replication and latent reactivation by stabilizing the expression of viral trans-activator of transcription Tat.

KRAShing pancreatic cancer before takeoff.

Cancer interception with KRAS inhibitors in preclinical models of pancreatic ductal adenocarcinoma.

A CD138+ tumor-associated macrophage-Siglec-F+ neutrophil feedforward loop promotes immune evasion in pancreatic cancer.

USP7 facilitates brain tumor survival upon glucose deprivation by regulating phosphofructokinase muscle-type nuclear translocation in mice.

Tissue Factor as a Prognostic and Therapeutic Biomarker in Resected Pancreatic Cancer.

Cancer Risk in Solid Organ Transplant Recipients With a Pretransplant Cancer History.

Hypochloremic Hypokalemic Metabolic Alkalosis as a Manifestation of CFTR-Related Disorder.

Metastatic Pancreatic Adenocarcinoma with Germline BLM and Somatic ATM Mutations: A Case Report and Review of DNA Damage Response.

[Evolution of thoracic computed tomography after therapy with elexacaftor, tezacaftor, and ivacaftor in patients with cystic fibrosis].

Structural mining and engineering of metagenome-derived Cas12a orthologs expands the CRISPR genome editing and multiplex diagnostics toolkit.

GALNT3 Inhibits the Progression of Cerebral Ischemia-Reperfusion Injury by Stabilizing TREM2 via O-GalNAc Glycosylation.

The SGLT2 Inhibitor Canagliflozin Promotes β-Cell Regeneration and Restores and Stabilises β-Cell Identity in a Polygenic Model of Severe Early-Onset Type 2 Diabetes.

CRISPR-Cas9 genome editing in the parental iPSC line PCIi033-A to introduce the homozygous mutation p.F508del (c.1521_1523del) in the CFTR gene.

Knockdown of Lymphoid Enhancer-binding Factor 1 Inhibits Pancreatic Adenocarcinoma Growth and Neoangiogenesis by Curbing Notch1 and Nuclear Factor Kappa B Signaling Pathways.

The Transcription Factor TFAP2A Induces M2 Macrophage Polarization by Upregulating EPS8L3 Expression, Thereby Accelerating the Malignant Progression of Pancreatic Ductal Adenocarcinoma.

Quality control strategy for differentiating induced pluripotent stem cells into pancreatic β-cells before transplantation.

Advances in non-invasive biomarkers for pediatric inflammatory bowel disease diagnosis.

Decoding liver injury in cystic fibrosis: How to tell drug-induced liver injury from cystic fibrosis liver disease.

Development and validation of a high-confidence diagnostic model integrating ctDNA methylation and serum biomarkers for early-stage hepatocellular carcinoma detection.

AGPAT3 reshapes tumor cell vulnerability to IFNγ-mediated ferroptosis and enhances immunotherapy efficacy through lipid remodeling.

CFTR Modulators in Brazil: Not for Everyone-A Comparison of Ineligibility Across Different Regions.

Protein-level profiling of TIGIT axis components in human PDAC reveals immune-suppressive expression patterns.

A MUC1-ALIX complex regulates extracellular vesicle cargo loading with activated SRC to enhance pancreatic cancer progression.

Interaction between m6A and YAP1 mechanotransduction pathways is essential for mechanical memory and matrix remodeling in pancreatic cancer.

Neutrophil extracellular traps prime the ZBP1-cGAS sensor complex, triggering necroptosis and inflammatory injury in acute pancreatitis.

S100A14 Facilitates Pancreatic Cancer Progression via S100A16-Mediated p53 Suppression.

OSBPL3-driven sterol metabolic reprogramming promotes oncogenic signaling and therapeutic resistance in pancreatic cancer.

Determinants of pancreatic tropism in metastatic renal cell carcinoma.

Disparities in Access to Cystic Fibrosis Therapy Across Countries.

Treatment of metastatic pancreatic cancer with concurrent BRAF V600E mutation and germline BRCA2 mutation: a case report.

KRAS-elicited PDIA6 blocks PERK-dependent immunogenic cell death in pancreatic carcinoma.

Double trouble: When focal and diffuse hyperinsulinism occur simultaneously.

MLPA-Detected CFTR Exon Deletions in Children With Inconclusive CFTR Sequencing: A Single-Center Experience From Türkiye.

Molecular taxonomy of pancreatic neuroendocrine tumors reveals BEND2-fusions-driven transcriptional plasticity and therapeutic vulnerabilities.

Clinical development of molecular residual disease (MRD) and multi-cancer early detection (MCED) using liquid biopsy multiomics with artificial intelligence (AI).

Integrative Molecular Analysis to Predict Clinical Benefit of Everolimus in Patients With Gastro-Entero-Pancreatic Neuroendocrine Tumors (GEP-NETs).

[Expression of Concern] c‑Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma.

Role of iron and TfR1 in the application of high‑dose ascorbate against pancreatic cancer.

Pancreatic cancer EMT‑targeted therapy: Molecular mechanisms and clinical translation (Review).

Urinary System Involvement in Children With Cystic Fibrosis: A Single-Center Retrospective Cohort.

High versus gradually increasing energy nutrition in the early phase of acute pancreatitis (GOULASH): a multicentre double-blind randomised clinical trial.

Targeting ACSS2 disrupts metabolic-epigenetic crosstalk to restore apoptosis and temozolomide chemosensitivity in pancreatic neuroendocrine tumors.

Senkyunolide I inhibits abdominal aortic aneurysm via PARP-1-targeted restraint of large peritoneal macrophage migration.

Impact of Germline BRCA Mutation Status on Antitumor Activity of Modified FOLFIRINOX in Patients With Advanced Pancreatic Cancer: An Exploratory Analysis.

Pseudomonas aeruginosa gene expression changes during established biofilm infection in a cystic fibrosis lung model.

Mitochondria-associated programmed cell death in pancreatic β cell of T2DM.

Nucleosome spacing across cell types, diseases, and ages.

A STING signaling relay from tumor cells to macrophages mediates the improved efficacy of combination chemotherapy in pancreatic cancer.

Cystic fibrosis year in review 2025.

Epigenetically regulated pancreatic GABA-somatostatin signaling underlies gestational diabetes-induced glucose intolerance in offspring.

Histone demethylase JMJD1A protects mice from enteric bacterial infection by upregulating CCL8 expression to recruit macrophages and CD4+ T cells.

MondoA mediates transcriptional coordination between the MYC network and the integrated stress response in pancreatic cancer.

Guidelines for endoscopic treatment of postinflammatory pancreatic and peripancreatic fluid collections. Recommendations of the Endoscopic Surgery Section of the Association of Polish Surgeons, the Endoscopy Section of the Polish Society of Gastroenterology, the Polish Pancreatic Club, the Laparoscopic and Robotic Surgery Section of the Association of Polish Surgeons, and the Pancreatic Surgery Section of the Association of Polish Surgeons; formulated by an expert panel led by Prof. Mateusz Jagielski, MD, PhD.

Beamion PANTUMOR-1: rationale and design of a Phase II trial of zongertinib in HER2-overexpressed/amplified or HER2-mutant solid tumors.

LINC00963 Targets miR-495-3p to Regulate Pancreatic Cancer Cell Proliferation, Apoptosis, and Carboplatin Sensitivity.

The TRIB1-PPARγ Axis Regulates Cholesterol Metabolism in Pancreatic Ductal Adenocarcinoma.

A Narrative Review of Gene-Environment Interactions in Pediatric Pulmonology.

Harm reduction in paediatric off-label therapy: ethical analysis of early CFTR modulator use in an infant with cystic fibrosis.

Unraveling pancreatic ductal adenocarcinoma at single-cell resolution with spatial insights: From mechanisms to clinical translation.

Phage isolation and functional characterization reveal strong antibiofilm activity against Pseudomonas aeruginosa in a cystic fibrosis sputum model.

Bilateral multifocal renal neuroendocrine carcinoma with synchronous pancreatic neuroendocrine carcinoma and adrenal lesion.

Genotype-phenotype correlations of fasting C-peptide and lipids in HNF1A-MODY: a single-center series and multi-center cross-sectional analysis in Chinese population.

Correlation between PD-L1 expression and clinical pathology, immunobiological markers, and prognosis in gastroenteropancreatic neuroendocrine neoplasms: a systematic review and meta-analysis.

Spatial transcriptomics reveals the mechanistic role of lactate metabolism in the pancreatic ductal adenocarcinoma microenvironment.

Macrophage-rich niches regulate T cell dynamics at the liver invasive margin during gallbladder cancer progression.

[MUC1 and SIGIRR as Negative Regulators of TLR Signaling: Expression, Function, and Anti-inflammatory Augmentation].

Effect of vanzacaftor/tezacaftor/ivacaftor on cystic fibrosis nasal epithelial cells and intestinal organoids compared to elexacaftor/tezacaftor/ivacaftor.

Islet-derived T cells from both mice and humans recognize conserved insulin A-chain peptides presented by HLA-C*03:04.

[Hearing impairment in children with cystic fibrosis].

In Utero CFTR Modulator Therapy in Fetuses With Cystic Fibrosis.

PPARδ: An underappreciated tumor accelerator in pancreatic ductal adenocarcinoma.

Genetic strategies for negative or variant of uncertain significance findings in exome sequencing in hereditary bronchiectasis: a case series.

Biomarker-directed aptamer panels for diagnosis and differentiation of neuroendocrine tumors.

Metabolic syndrome necroptosis: disease implications and therapeutic targeting.

Large variations in total and allele-specific transcript expression in a disease mutation-independent manner.

Beta cell-derived cholecystokinin drives obesity-associated pancreatic adenocarcinoma development.

Multiple endocrine neoplasia with an atypical clinical course and a MEN1 gene variant of uncertain pathogenicity: A case report.

The causal association between plasma amino acid levels and abdominal aortic aneurysm: insights from Mendelian randomization and an experimental validation.

Prognostic Impact of Metastatic Sites in Patients with Biliary Tract Cancer Treated with Cisplatin, Gemcitabine, and Durvalumab.

Challenges and Practical Solutions in the Management of Cystic Fibrosis in Resource-Limited Countries: The Indian Experience.

pH-Dependent Microenvironmental Ionic Signaling in Pancreatic Ductal Adenocarcinoma.

Clinical Impact of Semaglutide Beyond Glycemic Control: A Critical Analysis of Oncogenic Potential and Mitigation of Cardiotoxicity.

Pattern of HER2 and HER3 Overexpression in Patients with Pancreatic Ductal Adenocarcinoma.

Research Progress on the Biological Function, Disease-Driving Mechanism and Clinical Targeting Strategies of G3BP2.

Functional Foods as Modulators of Epigenetic Mechanisms Affecting Metabolic Health in Adolescence.

Selenium-Thioredoxin Axis Contributes to Ferroptosis Resistance in Pancreatic Cancer Cells.

Restoration of Defective CFTR in Human Nasal Respiratory Epithelial Cells by CFTR Modulators and mRNA Transfection.

A DNA Vaccine Incorporating the MHC Class I Trafficking Domain and PADRE Epitope Enhances Antitumor Immunity in a Murine Pancreatic Cancer Model.

Sleep-Disordered Breathing in Chung-Jansen Syndrome.

Review Article: Overview of Clinical Genetics of Diabetes Mellitus.

UBE3A-mediated mH2A1 Ubiquitination activates TERT transcription to promote senescence resistance in pancreatic cancer.

Unveiling the hidden genetic conundrum linking pulmonary diseases and neuropsychiatric disorders: Novel insights from advanced omics-based analyses of the lung-brain axis.

Acute pancreatitis as a severe complication of scoliosis surgery in pediatric patient: a case report and literature review.

Hypertriglyceridaemia-Associated Acute Pancreatitis: Risk Stratification, Drivers, and Prevention of Recurrence.

A Case of Ovarian Primary Solid Pseudopapillary Neoplasm With Multiple Organ Metastases.

Advancing Gene Therapy for Pancreatitis: From Genetic Insights to Clinical Translation.

A disease model resource reveals core principles of tissue-specific cancer evolution.

SEL1L-HRD1 ER-associated degradation facilitates prohormone convertase 2 maturation and glucagon production in islet α cells.

MUC15 loss promotes perineural invasion in pancreatic cancer by activating the IGF1R/STAT3/NGF pathway.

Risk-stratified surveillance for individuals in the UK at high risk of developing pancreatic cancer: Outcomes from the European Registry of Hereditary Pancreatic Diseases (EUROPAC).

Dual calcium-ACE inhibition reverses non alcoholic fatty pancreas progression: Mechanistic convergence on miR-762/GPX4 driven NLRP3 inflammasome activation.

Commentary on "Comparative efficacy and safety of PSCA CAR-engineered Vδ1 γδ T cells for immunotherapy of pancreatic cancer".

Contribution of two-component regulatory systems to the acute-to-chronic infection transition of Pseudomonas aeruginosa in cystic fibrosis.

Role of lipid rafts in the FGFR2c-mediated oncogenic signaling by involvement of TRPA1 channel in pancreatic ductal adenocarcinoma cells.

[A specific situation: the genetic pancreatitis].

[Etiological work-up for chronic pancreatitis].

[Definition, diagnosis and differential diagnostics of chronic pancreatitis].

Exploring dietary habits strongly associated with pancreatic cancer from the perspective of Mendelian randomization.

Treating Pancreatic Ductal Adenocarcinoma: The Targeted Revolution is Here.

Genetic regulation across germline and somatic variation on the Y chromosome contributes to type 2 diabetes.

Multianimal Magnetic Resonance Imaging for Tumor Measurements in Pancreatic Cancer Mouse Models.

When One Gland Speaks First: Autoimmune Polyendocrinopathy Syndrome Type 1 (APS-1) Unmasked by Isolated Hypoparathyroidism.

A plasma-based DNA test for quantification of disease burden in acute myeloid leukemia patients undergoing bone marrow transplantation.

[Bisalbuminemia: a report of three cases collected at the biochemistry laboratory of Mohammed VI University Hospital in Oujda, Morocco, and a literature review].

Comprehensive analysis of mitochondrial unfolded protein response related genes for prognosis and therapeutic response in pancreatic cancer.

Multi-scale systems toxicology defines a KLF5-centered adverse outcome pathway linking DEHP exposure to pancreatic cancer progression and signaling programs relevant to therapy tolerance.

Molecular classification and prognosis study of pancreatic ductal adenocarcinoma through multi-omics integrated clustering analysis.

Soluble LAG-3 Identifies a Dynamic Early T Cell Activation Window in self-reactivity, Type 1 Diabetes, and Broader Immune Responses.

Respiratory Oscillometry and Multimodal Lung Function Assessment of Elexacaftor/Tezacaftor/Ivacaftor Response in Children and Young Adults With Cystic Fibrosis.

BiGCN Learns B Cell Functional States by Integrating Single-Cell Transcriptomes and BCR Repertoires.

Integrative Transcriptomic and Proteomic Profiling Defines Secretory and Immune Related Subtypes in Pancreatic Ductal Adenocarcinoma.

Changes in the 6th edition of the World Health Organization classification of tumours of the digestive system.

Cystic lesions and their role in pancreatic cancer risk stratification.

α-ketoglutarate/succinate ratio imbalance impairs thymine DNA glycosylase function and base excision repair process increasing susceptibility to pancreatic cancer.

Targeting mitochondrial phosphatase PGAM5 alleviates ferroptosis and acute pancreatitis by upregulating NRF2-mediated FSP1 expression.

MIF-CD74 axis facilitates MDSC infiltration in the tumor microenvironment of pancreatic ductal adenocarcinoma.

Identification of circulating microRNA signature in pancreatic ductal adenocarcinoma and chronic pancreatitis patients from Indian population.

ETS1 potentiates pancreatic Pyroptosis in mice with acute pancreatitis by regulating the NKIRAS1/NF-κB Axis.

FGTI-2734 prevents ERK-mediated resistance and enhances MRTX1133 efficacy in KRAS G12D pancreatic cancer.

Aerobic training and cannabidiol activate the PI3K/AKT/PDX1 axis to ameliorate beta-cell dysfunction in a rat model of diet-induced obesity.

Anticancer effect of palmitoyl piperidinopiperidine against human pancreatic ductal adenocarcinoma cells.

Evidence that extra copies of chromosome 1q play a role in the early phases of pancreatic neoplasia.

KRASG12V/HLA-A*02:01-targeted chimeric antigen receptor T cells exhibit potent preclinical activity against solid tumors.

Contrasted modifications of IgM and IgT repertoires induced by high- and low-virulent infectious pancreatic necrosis virus strains in rainbow trout (Oncorhynchus mykiss).

Single-cell and spatial transcriptomics reveal transplant-associated T cells and myeloid cells in human liver transplantation.