Uveíte posterior

Birdshot Chorioretinopathy : Prospective Follow-up and Immunogenetic Studies(CO-BIRD)

NCT05153057

RECRUTANDO

The Use of Two YUTIQ Versus Sham for Treatment of Chronic Non Infectious Intraocular Inflammation Affecting the Posterior Segment

NCT05486468

RECRUTANDO

A Study of Brepocitinib in Adults With Active, Non-Infectious, Non-Anterior Uveitis

NCT06431373

EM ANDAMENTO

Targeting Immunosuppressive Treatment for Non-infectious Uveitis Using Aqueous Humor Cytokine Profiles

NCT07262437

EM ANDAMENTO

Fluocinolone Acetonide Intravitreal Implant 0.18 mg in the Treatment of Chronic Non-Infectious Posterior Segment Uveitis

NCT05322070

EM ANDAMENTO

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NCT05153057 · Birdshot Chorioretinopathy : Prospective Follow-up and Immun…Recrutando

NCT05486468 · The Use of Two YUTIQ Versus Sham for Treatment of Chronic No…Recrutando

PHASE3

Outros ensaios clínicos

94 ensaios clínicos encontrados, 7 ativos.

Distribuição por fase

NCT06431373 · A Study of Brepocitinib in Adults With Active, Non-Infectiou…Ativo

PHASE3

NCT07262437 · Targeting Immunosuppressive Treatment for Non-infectious Uve…Ativo

NA

NCT05322070 · Fluocinolone Acetonide Intravitreal Implant 0.18 mg in the T…Ativo

NCT07423442 · Frequency and Intensity of Inflammatory Relapses in Patients…Em breve

NCT06743906 · Role of OCT & OCT Angiography in Patients With Posterior at …Em breve

NCT02931175 · ACTH as A Re-emerging theRapy for Uveitis (The ACTHAR Study)Concluído

NCT05523765 · A Study of Brepocitinib in Adults With Active Non-Infectious…Concluído

NCT05101928 · Ozurdex Monotherapy TrialCancelado

NCT05384249 · Phase 2b Pivotal Study of Izokibep in Non-infectious, Interm…Encerrado

NCT05070728 · Safety and Efficacy of an Injectable Fluocinolone Acetonide …Encerrado

PHASE3

NCT06613919 · Six-months Versus Nine-months ATT for Ocular TBConcluído

NCT05953688 · POC Study to Evaluate the Efficacy and Safety of ESK-001 in …Encerrado

NCT00499551 · A Phase I/IIa Study for the Treatment of Uveitis With Iontop…Cancelado

PHASE1, PHASE2

NCT01280669 · Intravitreal Sirolimus as Therapeutic Approach to UveitisCancelado

NCT06085079 · Ixekizumab for the Management of Refractory Non-Infectious U…UNKNOWN

NCT00539370 · Human Samples and Data RepositoryEncerrado

NCT03753893 · Ocular Manifestations in Rheumatic DiseasesConcluído

NCT03656692 · Safety and Effectiveness of Acthar Gel for Inflammation of t…Encerrado

Ver todos no ClinicalTrials.gov

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Publicações mais relevantes

Timeline de publicações

1.089 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 1.089

#1

Are the SUN Criteria Sufficient for Tubercular Uveitis? Findings From a Multinational Registry Study.

Investigative ophthalmology & visual science2026 Jan 05

The Standardization of Uveitis Nomenclature (SUN) criteria were introduced in 2021 to standardize the classification of uveitis subtypes. We evaluated the real-world applicability of these criteria for tubercular uveitis (TBU) using a computational definition mapped to the Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) registry. This observational retrospective cross-sectional study analyzed real-world baseline data from 372 clinician-diagnosed TBU cases within the multinational OASIS registry, all collected from 17 tertiary centers across 8 countries: India, Nepal, Indonesia, Switzerland, Ethiopia, Colombia, Argentina, and Chile. We mapped the SUN criteria to corresponding variables in the OASIS registry, and Boolean operators were used to generate a computational definition for TBU. The sensitivity of the SUN criteria in capturing clinician-diagnosed cases of TBU was evaluated. The SUN criteria identified 15.9% (n = 59) of clinician-diagnosed TBU cases at baseline. Criterion f2 (evidence of TB infection) was met in 70.7% of cases (n = 263), and criterion f1 (TBU-compatible uveitic syndrome) was satisfied in 24.5% of cases (n = 91). Exclusion criterion successfully identified 99.5% of cases (n = 370). By country and anatomical location, cases in India and those with posterior uveitis had the highest concordance at 19.8% (n = 39) and 21.8% (n = 44), respectively. Bilateral TBU was more likely to satisfy the SUN criteria (P = 0.049). SUN classification criteria demonstrated low sensitivity for real-world TBU diagnosis at baseline, which may limit the number of cases available for enrollment in research studies. Further diagnostic refinement, clearer definition of application context, and longitudinal validation are needed to generate diagnostic criteria for clinical application.

#2

A triamcinolone acetonide palmitate nanoemulsion eye drop delivered by iontophoresis for the management of posterior uveitis.

International journal of pharmaceutics2026 Mar 21

Uveitis is a leading cause of global vision loss. Local corticosteroid therapy, notably intravitreal or suprachoroidal triamcinolone injections, remains central to its clinical management. However, frequent intraocular injections and poor patient compliance substantially increase the risk of complications such as endophthalmitis. Although eye drops represent a more attractive noninvasive alternative, their efficacy in treating posterior segment diseases is severely limited by ocular defense mechanisms, resulting in extremely low bioavailability (<5%). To address these challenges, we propose a strategy combining prodrug modification with physical permeation enhancement. Triamcinolone acetonide was converted into an ester prodrug and formulated into a nanoemulsion using a reverse emulsification method. When coupled with iontophoresis, this system significantly improved drug delivery efficiency to the posterior segment of the eye. In a rabbit model of experimental autoimmune uveitis (EAU), a single administration of triamcinolone acetonide palmitate nanoemulsion (TAP-NE) sustained anti-inflammatory effects for up to 14 days. It significantly downregulated inflammatory cytokines including IL‑6 and IL‑17, and alleviated uveitis by suppressing the activation of retinal macroglia (GFAP) and microglia (IBA‑1). Furthermore, it maintained blood-retinal barrier (BRB) integrity, thereby preventing subsequent intraocular damage. Safety evaluations confirmed its favorable biocompatibility, with no detectable ocular irritation or tissue injury. The TAP-NE system combined with iontophoretic delivery developed in this study offers a novel strategy for addressing uveitis as well as other ocular conditions associated with inflammatory processes.

#3

Imaging Measures for the Assessment of Disease Activity in Non-Infectious Posterior Uveitis - Multimodal Imaging in Uveitis (MUV) Taskforce: Report 10.

American journal of ophthalmology2026 Mar 18

To develop imaging-based measures for disease assessment in non-infectious posterior uveitis (NIPU). A mixed-methods design, beginning with a review of previously developed imaging recommendations formulated by separate subcommittees of the Multimodal Imaging in Uveitis (MUV) initiative, followed by a structured consensus process using the Nominal Group Technique (NGT), facilitated by an independent expert committee. An expert committee reviewed and extracted all consensus-based imaging recommendations by the MUV subcommittee manuscripts focused on five major NIPU entities. The primary objective was to categorize imaging features as suggestive of active disease (SAD), suggestive of inactive disease (SID), or equivocal. This process was conducted using the NGT to reach consensus-based imaging measures. These recommendations were further voted upon by members of the full task force. A total of 49 imaging statements were deliberated using two rounds of NGT and independent voting. For the five included diseases, a total of 21 statements qualified as features of SAD, whereas 12 statements were classified as SID. The remaining 16 statements were categorized as equivocal features, that need further investigation to determine whether the disease is active. This study builds upon the multinational efforts of the MUV initiative to extend the Standardization of Uveitis Nomenclature (SUN) work through the integration of additional multimodal imaging information. By defining clear imaging-based outcome measures for NIPU, it establishes a structured framework supporting objective disease assessment. These standardized imaging measures are expected to enhance the utility of multimodal imaging in both routine uveitis care and future clinical trials.

#4

NON-INFECTIOUS POSTERIOR UVEITIDES - Atypicals, Variants, and Masquerades: the jungle of differential diagnosis.

American journal of ophthalmology2026 Mar 18

Non-infectious posterior and panuveitides (NIPUs) comprise a heterogeneous group of inflammatory disorders of the outer retina and choroid, historically referred to as "white dot syndromes." Recent consensus efforts by the Multimodal Imaging in Uveitis (MUV) Task Force have established standardized diagnostic criteria for the major NIPUs, including multiple evanescent white dot syndrome (MEWDS), multifocal choroiditis and panuveitis/punctate inner choroiditis (MFCPU/PIC), acute posterior multifocal placoid pigment epitheliopathy (APMPPE), serpiginous choroiditis, and birdshot chorioretinopathy (BSCR). Nevertheless, a substantial proportion of cases deviate from classical presentations and fall into diagnostic "grey zones", blurring boundaries between diseases entities and complicating both differential diagnosis and management. This review aims to describe the broad spectrum of atypical, variant, and secondary forms of NIPUs as well as masquerade syndromes. Atypical MEWDS includes bilateral presentations or complicated courses, while MFCPU/PIC with outer retinal atrophy emerges as a notable entity with unclear therapeutic implications. Inflammatory reactions resembling both MEWDS and MFCPU/PIC may also occur as secondary phenomena, triggered by other chorioretinal disorders, most notably inherited retinal diseases (IRDs). Placoid chorioretinopathies, including APMPPE, persistent placoid maculopathy, serpiginous choroiditis, and relentless placoid chorioretinitis, are often distinguished only a posteriori based on disease course, but likely represent a continuum of disorders unified by choroidal ischemia. Atypical presentations of BSCR may feature extensive outer retinal damage, mimicking IRDs. Equally important is the consideration of masquerade syndromes in all suspected cases of NIPUs, as they can present with similar features yet require entirely different treatments. Infectious masquerades include tuberculosis-associated serpiginous-like choroiditis, acute syphilitic posterior placoid chorioretinopathy, and West Nile virus chorioretinitis, whereas vitreoretinal lymphoma is the most frequent neoplastic masquerade. In conclusion, integrating clinical context with high-quality multimodal imaging remains essential to navigate the jungle of differential diagnosis in NIPUs, while future studies should aim to link imaging phenotypes with immune and molecular biomarkers to refine classification and guide targeted therapies.

#5

Combined PCR Positivity for Mycobacterium tuberculosis Complex and Nontuberculous Mycobacterium Species in Patients Treated for Tubercular Panuveitis.

Ocular immunology and inflammation2026 Mar 13

Intraocular dual infection by Mycobacterium tuberculosis complex (MTBC) and non-tuberculous mycobacteria (NTM) is rarely reported. This study describes the clinical features, aetiology, and treatment outcomes of patients with dual infection from MTBC and NTM-related uveitis. A retrospective study was conducted on 146 clinically suspected tubercular uveitis (TBU) patients who underwent diagnostic or therapeutic pars plana vitrectomy as plan of laboratory diagnosis-based management between June 2023 and December 2024. Undiluted vitreous samples were analysed with nested MTBC-NTM multiplex real-time PCR assay kit. Six out of 146 patients (4.11%) were found infected with dual infection from MTBC and NTM. All six cases showed severe clinical presentation characterised by bilateral panuveitis (5/6 patients), with significant structural sequelae. Optic atrophy was universal and occurred more frequently than in isolated TBU, while complicated cataract and hypotony-related maculopathy were also common. Despite the dual etiology, all patients achieved inflammatory resolution and visual recovery (mean BCVA improving from 20/400 to 20/100) following standard anti-tubercular therapy (ATT) and corticosteroids, with no recurrence during follow-up. Concurrent MTBC and NTM infection drives a distinct, aggressive form of panuveitis characterized by optic nerve pallor, anterior segment complications of complicated cataract or uveitic membranes and maculopathy. Despite this severity, standard ATT remained an effective first-line strategy, likely either due to therapeutic cross-coverage against NTM or MTBC being the primary driver of uveitis in the present study. The concurrent positivity also highlights the need for vitreous molecular profiling and further research in co-infections in infectious posterior uveitis.

Publicações recentes

QuantiFERON-TB gold test: a valuable diagnostic tool for tubercular uveitis in non-endemic regions.

Infection2026 Apr 17

Characteristics of Uveitis in European Tertiary Ophthalmology Centers: A Systematic Review and Meta-Analysis.

Ocul Immunol Inflamm2026 Apr 17

Retinal pigment epithelium drives macrophage migration during Toxoplasma gondii infection in vitro.

Mem Inst Oswaldo Cruz2026

Immunoglobulin G4-Related Disease Manifesting as Posterior Uveitis.

J Vitreoretin Dis2026 Mar 31

Bilateral Multifocal Choroiditis in Polymyositis: A Case Report and Review of the Literature.

Retin Cases Brief Rep2026 Apr 1

Ver todas no PubMed

📚 EuropePMC372 artigos no totalmostrando 198

International journal of pharmaceutics

A triamcinolone acetonide palmitate nanoemulsion eye drop delivered by iontophoresis for the management of posterior uveitis.

Imaging Measures for the Assessment of Disease Activity in Non-Infectious Posterior Uveitis - Multimodal Imaging in Uveitis (MUV) Taskforce: Report 10.

NON-INFECTIOUS POSTERIOR UVEITIDES - Atypicals, Variants, and Masquerades: the jungle of differential diagnosis.

The Multimodal Imaging in Uveitis Virtual Special Issue.

Combined PCR Positivity for Mycobacterium tuberculosis Complex and Nontuberculous Mycobacterium Species in Patients Treated for Tubercular Panuveitis.

World journal of clinical cases

Tubercular chorioretinitis mimicking sarcoidosis in a patient with celiac disease and erythema nodosum: A case report.

American journal of ophthalmology case reports

Ocular manifestations of STAT3 gain-of-function syndrome: A case of papillitis, retinitis, and retinal vasculitis.

International journal of STD & AIDS

Ocular syphilis: Clinical characteristics, HIV status, and outcomes in a 10-year case series from Türkiye.

Resurgence of Ocular Syphilis: HIV Co-Infection, Clinical Manifestations, and High-Risk Sexual Behaviour in an Indonesian Cohort.

Klinische Monatsblatter fur Augenheilkunde

Immunology of Uveitis - From Bench to Bedside.

Epidemiology of Uveitis and Extra-Uveal Inflammation in a Referral Center in Central Italy.

Chasing shadows: case series of six posterior segment manifestations of ocular tuberculosis.

AME case reports

Beyond placoid: diverse clinical presentations and functional outcomes of acute syphilitic posterior placoid chorioretinopathy.

Eye (London, England)

The Spectrum of Uveitis and Retinal Vasculitis in Systemic Sclerosis: A Case Series.

Birdshot Chorioretinopathy in a Patient of Filipino Ancestry: A Case Report.

[Ocular toxoplasmosis in adults : Refresher course].

Die Ophthalmologie

Paracentral Acute Middle Maculopathy Associated With Dengue Fever.

Causes of Visual Loss in Uveitis: A Retrospective Study at a Tertiary Referral Centre.

Indian journal of ophthalmology

The protein-protein interaction network analysis in idiopathic posterior uveitis.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Ocular findings in patients with lyme disease: a systematic review and meta-analysis.

Investigative ophthalmology & visual science

Are the SUN Criteria Sufficient for Tubercular Uveitis? Findings From a Multinational Registry Study.

Noncancerous Monogenic Mimics of Noninfectious Posterior Uveitis.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Systemic immunosuppressive therapy in idiopathic non-infectious uveitis and scleritis: disease remission, discontinuation, and relapse patterns.

Pathogens (Basel, Switzerland)

Intraocular Coinfection by Toxoplasma gondii and EBV Possibly Transmitted Through Unpasteurized Goat Milk in an Immunocompetent Patient: A Case Report.

Epidemiological and clinical profiles of ocular involvement in rickettsiosis in southern Tunisia.

Infectious disease reports

The Evolution of Artificial Intelligence in Ocular Toxoplasmosis Detection: A Scoping Review on Diagnostic Models, Data Challenges, and Future Directions.

Birdshot Chorioretinopathy with Double-Layer Sign and Choroidal Neovascularization: A Single-Centre Analysis.

Interpretable multi-model deep learning framework for automated four-class diagnosis of ocular toxoplasmosis using fundus imaging.

Scientific reports

Diagnostics (Basel, Switzerland)

Structural Retinal Analysis in Toxoplasmic Retinochoroiditis: OCT Follow-Up with Three-Dimensional Reconstruction.

Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society

Opposing pathophysiological concepts in multiple evanescent white dot syndrome: The great MEWDS schism.

Seminars in ophthalmology

Six-Month Versus Nine-Month Anti-Tubercular Therapy for Tubercular Posterior Uveitis: A Multicenter, Randomized Controlled Trial.

International journal of retina and vitreous

Intraocular inflammation following aflibercept 8 mg: real-world data from a multicentre retrospective observational study.

Clinical Profile, Management and Visual Outcomes in Patients with Sarcoid Posterior Uveitis.

Case reports in ophthalmology

Progressive Subretinal Fibrosis and Uveitis Associated with Hodgkin Lymphoma.

Seminars in ophthalmology

Intraocular Tuberculosis: Current Insights and Emerging Therapeutic Paradigms.

Veterinary research communications

Pyogranulomatous endophthalmitis and posterior uveitis in a crested capuchin (Sapajus robustus) with systemic Paracoccidioides brasiliensis infection.

Clinical medicine & research

Ocular Manifestations of Pediatric Behçet's Disease.

Journal of ophthalmic & vision research

Hyperreflective Choroidal Foci: A Comprehensive Review.

Resurgence of Acquired Syphilitic Uveitis: Characteristics, Challenges and Outcomes.

Presumed Ocular Tuberculosis: Insights from an Egyptian Cohort.

Journal of clinical medicine

Repository Corticotropin Therapy for Refractory Noninfectious Inflammatory Ocular Diseases.

International journal of molecular sciences

Atypical Presentations and Molecular Diagnosis of Ocular Bartonellosis.

Management of uveitic and chorioretinal conditions in pregnancy.

Eye (London, England)

Serum Concentrations of Th1, Th2 and Treg-Associated Cytokines in Patients With Ocular Toxoplasmosis.

Parasite immunology

Clinical utility of ultra-widefield indocyanine green angiography in posterior uveitis.

Adalimumab in non-infectious uveitis, towards a real-world therapeutic paradigm beyond inflammation control: A multicenter cross-sectional study.

Ophthalmic surgery, lasers & imaging retina

Isolated Immunoglobulin G4-Related Uveitis Diagnosed by Choroidal Biopsy.

Clinical and Organizational Determinants of a Frequently Delayed Diagnosis of Ocular Syphilis in a French Referral Center.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Self-assembled rapamycin prodrug nanoparticles for posterior segment targeting and effective treatment of experimental uveitis.

Adalimumab versus Conventional Immunosuppression for Uveitis (ADVISE) Trial.

Nonmydriatic Ocular Fundus Imaging on Consecutive Patients Seeking Treatment at a General Emergency Department with Vision Symptoms.

Evaluating the Effectiveness of Escalating to Weekly Adalimumab Dosing for the Treatment of Noninfectious Uveitis: A Multicenter Study.

Journal of veterinary internal medicine

Treatment With Remdesivir Alone or in Combination With GS-441524 in Cats With Ocular Involvement of Feline Infectious Peritonitis: An Observational Case Series.

Role of Fundus Autofluorescence in Candida Chorioretinitis: Insights from a Clinical Case.

The relationship between retinal vascular tortuosity and retinal vasculitis.

Pathogens (Basel, Switzerland)

Syphilis and the Eye: Clinical Features, Diagnostic Challenges, and Evolving Therapeutic Paradigms.

Long-term management of recurrent uveitis associated with autoimmune lymphoproliferative syndrome.

Common data elements for observational studies in ocular toxoplasmosis: a Delphi consensus.

Archivos de la Sociedad Espanola de Oftalmologia

Safety and efficacy profile of the fluocinolone acetonide implant in non-infectious uveitic macular edema: 5-year follow-up.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)

Controversy and consensus on the management of ocular toxoplasmosis: A joint statement by the Asia-Pacific Society of Ocular Inflammation and Infection (APSOII), the Asia-Pacific Vitreo-Retina Society (APVRS), the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) and The Infectious Uveitis Treatment Algorithm Network (TITAN) Group.

Retina (Philadelphia, Pa.)

MULTIMODAL IMAGING AND LONG-TERM TREATMENT OUTCOMES OF RELENTLESS PLACOID CHORIORETINITIS.

Specific Skin Lesions of Sarcoidosis in the Diagnosis of Ocular Sarcoidosis.

Risk Factors for Development of Uveitis and Cystoid Macular Edema After Cataract Surgery.

Turkish journal of ophthalmology

Prevalence and Prognosis of Glaucoma/Elevated Intraocular Pressure in Patients with Uveitis.

Are dexamethasone implants a safe and effective breakthrough in uveitis treatment? A systematic review and meta-analysis.

Steroids

Indian journal of dermatology, venereology and leprology

The causal relationship between uveitis and psoriatic arthritis: A bidirectional Mendelian randomisation study.

Demographic and Clinical Characteristics of Pediatric Uveitis Cases from a Referral Center in Turkey.

International journal of surgery case reports

Type 1 inflammatory choroidal neovascular membrane in a case of viral uveitis - a case report.

Minimum Imaging Sets for Diagnosis, Activity Assessment, and Complications in Noninfectious Posterior Uveitis - Multimodal Imaging in Uveitis (MUV) Task Force Report 9.

Correlation Between Optical Coherence Tomography (OCT) and Serum Indirect Immunofluorescence Findings in a Case of Cancer Associated Retinopathy (CAR) Masquerading as White Dot Syndrome.

Epidemiology and Clinical Features of Uveitis in Southwestern Japan: Laterality and Long-Term Visual Prognosis Based on the Anatomical and Epidemiological Classification.

Systemic Immunosuppression and Secondary Choroidal Neovascularisation in Patients with Punctate Inner Chorioretinopathy.

Ocular Insights: Exploring Uveitis as a Manifestation of Celiac Disease.

Investigational new drugs

Clinical features, treatment and outcomes of dabrafenib-associated uveitis.

Relentless placoid chorioretinitis.

Romanian journal of ophthalmology

Sulfonamide Allergy and Alternative Treatments in Ocular Toxoplasmosis.

Multizonal outer retinopathy and retinal pigment epitheliopathy (MORR) with a chronologically divergent presentation- a case report.

Indian journal of ophthalmology

Clinical outcomes of cyclophosphamide therapy in relentless placoid choroiditis: A descriptive case series.

Rapid contraction of the anterior capsule after phacoemulsification in uveitis: A case report.

Medicine

Systematic Review of Clinical Utility of Multimodal Imaging in Noninfectious Posterior Uveitis: MUV Project Report 3.

AIDS research and therapy

Risk of uveitis in patients with human immunodeficiency virus: a cohort study through TriNetX database.

International ophthalmology clinics

Pediatric Noninfectious Intermediate, Posterior, and Panuveitis: A Review.

Drug-Induced Uveitis: Patterns, Pathogenesis and Clinical Implications.

Clinical optometry

International ophthalmology

Treatment of ocular sarcoidosis. Study of 65 patients from a series of 342 from a university hospital in northern Spain.

Life (Basel, Switzerland)

Etiology and Anatomical Location of Uveitis-Prognostic Factors for Disease Course and Laterality.

Evidence and Consensus-Based Imaging Guidelines in Noninfectious Posterior Uveitis-Methodology of the Multimodal Imaging in Uveitis (MUV) Project Report 2.

Corticosteroids with or without Conventional Disease-Modifying Antirheumatic Drug as First-Line Therapy in Nonanterior Sarcoidosis Uveitis.

Incidence and Prevalence of Syphilitic Uveitis and Associated Ocular Complications in the TriNetX Database.

Archivos de la Sociedad Espanola de Oftalmologia

Infectious uveitis: Epidemiology, etiology, diagnostic test performance and treatment.

Physician Burden and Time Delays in Initiating Immunomodulatory Therapy for Noninfectious Uveitis and Inflammatory Eye Diseases.

Uveitis in Adults: A Review.

JAMA

Comparative Effectiveness of Intravenous versus Subcutaneous Tocilizumab for Refractory Uveitis: A Retrospective Analysis.

Clinical & translational immunology

Antigen-specific polyfunctional cytotoxic T cells differentiate intraocular from peripheral blood immune responses in posterior uveitis.

Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti

Uveitis associated with juvenile idiopathic arthritis (JIA) and JIA-like uveitis in pediatric patients.

Prevalence, Treatment Patterns, and Outcomes of Pediatric Noninfectious Uveitis in the United States: An IRIS Registry Analysis.

Ophthalmology. Retina

Treatment outcomes of a Swiss non-infectious paediatric uveitis cohort: retrospective study over ten years.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)

Programme for ocular inflammation & infection translational research (PROTON) registry: Cross-sectional analysis of baseline patient characteristics.

Optic disc pit: A trigger for secondary multiple evanescent white dot syndrome.

Revista medica del Instituto Mexicano del Seguro Social

[Peripheral ulcerative keratitis with necrotizing scleritis, manifestation of granulomatosis with polyangiitis].

Atypical Presentation of Frosted Branch Angiitis due to Ocular Toxoplasmosis: A Case Report.

Active Juxtapapillary Toxoplasmic Retinochoroiditis Presenting with Henle Fiber Hemorrhages.

The clinical safety landscape for ocular AAV gene therapies: A systematic review and meta-analysis.

iScience

Diagnostics (Basel, Switzerland)

Epidemiology of Uveitis from a Tertiary Referral Hospital in Bulgaria over a 13-Year Period.

Journal for immunotherapy of cancer

Consensus disease definitions for ophthalmic immune-related adverse events of immune checkpoint inhibitors.

Occlusive Retinal Vasculitis After Aflibercept 8mg Injection for Wet Macular Degeneration.

International medical case reports journal

Intravitreal Corticosteroids in the Management of Refractory Macular Edema in Birdshot Chorioretinopathy.

Occult invasive fungal sinusitis in a patient with acute Vogt-Koyanagi-Harada Disease (VKHD).

Cumulative incidence of macular edema in non-infectious uveitis indicates an early therapeutic window.

Acta ophthalmologica

Inherited retinal disease-associated uveitis.

[Ten-year study of the epidemiology and clinical features of uveitis in Picardie, France].

BILATERAL SEQUENTIAL INFLAMMATORY FULL-THICKNESS MACULAR HOLES IN BIRDSHOT CHORIORETINOPATHY.

Frontiers in pharmacology

Case report: Effectiveness of Janus kinase inhibitors in the management of isolated noninfectious uveitis: a case series.

ROSAH syndrome presenting with recurrent vitreous hemorrhage: a multimodal imaging study.

Ophthalmic genetics

Quantitative autofluorescence is increased in clinically unaffected fellow eyes from patients with posterior uveitis.

Scientific reports

Journal of epidemiology and global health

The Clinical Spectrum and Outcomes of Ocular Syphilis in Saudi Arabia: The Emergence of a Uveitic Masquerader.

Journal of medical case reports

Multiple evanescent white dot syndrome masquerading as atypical optic neuritis: a case report.

Electrodiagnostic Tests as Potential Efficacy Endpoints in Clinical Trials of Novel Pharmacological Therapies for Acquired Retinal Disorders.

Ophthalmic research

Nanomedicine (London, England)

Polyol-modified deformable liposomes fortified contact lenses for improved ocular permeability.

Symptomatic Occlusive Retinal Vasculitis as an Unusual Presentation of Biopsy-Proven Sarcoidosis: A Case Series.

Klinische Monatsblatter fur Augenheilkunde

Inflammatory Choroidal Neovascularization in Pediatric Uveitis: A Case Series.

Delayed-Onset White-Dot Syndrome in the Setting of Traumatic Choroidal Rupture.

Sexually transmitted infections

Trends in syphilis and syphilitic uveitis among South Korean adults in 2010-2019: a nationwide cohort study.

Indian journal of sexually transmitted diseases and AIDS

Posterior uveitis of syphilitic etiology.

Immunopharmacology and immunotoxicology

Clinical characteristics, treatment, and outcomes of nivolumab-induced uveitis.

Klinische Monatsblatter fur Augenheilkunde

Prospective International Registry for Treatment Exit Options in Uveitis (TOFU) - the First Five Years.

Comparative evaluation of funduscopy, PCR and serology in the diagnosis of ocular toxoplasmosis at ECWA Eye Hospital, Kano.

BMJ open ophthalmology

HLA-G Polymorphisms of The 3'-UTR Region Are Involved in Susceptibility to Non-Infectious Uveitis.

Bacillary layer detachment: Updates on its clinical and prognostic significance in retinal disease.

Acute macular neuroretinopathy occurrence in a Behçet disease patient: a case report.

Demographic Features, Diagnoses and Real-World Clinical Management of Uveitis in Japan.

Spectrum of Imaging Characteristics of Birdshot Chorioretinopathy.

Uveitic macular oedema in ocular tuberculosis patients in a non-endemic country: characteristics, management, and visual Outcomes.

Eye (London, England)

The Medical journal of Malaysia

Unilateral vitritis in an immunocompetent individual - A rare presentation of ocular toxoplasmosis.

Diagnostics (Basel, Switzerland)

Analysis of the Incidence of Ocular Extraintestinal Manifestations in Inflammatory Bowel Disease Patients: A Systematic Review.

Retina (Philadelphia, Pa.)

INTRAOCULAR INFLAMMATION ASSOCIATED WITH FARICIMAB THERAPY: One-Year Real-World Outcomes.

Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti

Chorioretinitis Associated with HSV-1 Neuroinfection Following Viral Infection. A Case Report.

Inflammatory choroidal neovascularization: An evidence-based update.

Demography in Swiss paediatric uveitis: a retrospective cohort study.

International journal of molecular sciences

Targeting Oxidative Stress and Inflammation in the Eye: Insights from a New Model of Experimental Autoimmune Uveitis.

Pattern of Uveitis in Northern Vietnam.

Ocular findings in neurosyphilis: a retrospective study from 2012 to 2022.

Frontiers in neurology

Pattern of Uveitis in a Tertiary Care Eye Hospital Setting in Pakistan: A Comprehensive Analysis.

Stage 1 Extensive Macular Atrophy with Pseudodrusen-Like Appearance Complicated by Multiple Evanescent White Dot Syndrome-Like Reaction.

European journal of ophthalmology

Ocular manifestations of West Nile virus infection: A case report and systematic review of the literature.

Patterns and Outcomes of Pediatric Uveitis in a University-Based Tertiary Referral Center in Riyadh, Saudi Arabia.

Choroidal vasculitis as a biomarker of inflammation of the choroid. Indocyanine Green Angiography (ICGA) spearheading for diagnosis and follow-up, an imaging tutorial.

International ophthalmology

Changing age pattern and diverse outcomes of herpes zoster ophthalmicus: exploring the temporal trend, decrease in incident age and influence of treatment strategies.

Travel medicine and infectious disease

Ocular infections in international travelers.

Oxford medical case reports

Posterior localized nodular scleritis mimicking malignancy, a case report and clinical approach.

CMV-Related Hemorrhagic Retinal Vasculitis in a Multiple Myeloma Patient on Daratumumab Therapy: A Case Report.

Multimodal imaging findings of multiple evanescent white dot syndrome in COVID-19 patients.

IDCases

"Infectious uveitis: a comprehensive systematic review of emerging trends and molecular pathogenesis using network analysis".

ACS medicinal chemistry letters

Novel Plasma Kallikrein Inhibitors for Treating Multiple Diseases.

Serpiginous Choroiditis After COVID-19 Infection.

Multimodal Imaging of a Unique Transitory Finding in Ocular Syphilis.

Mycophenolate Mofetil-Induced Lymphoproliferative Disorder in a Young Adult With Chronic Posterior Uveitis.

Is it Time to Adopt a New Nomenclature and Classification for White Dot Syndromes Using Multimodal Imaging Techniques? Report 1 from Multimodal Imaging in Uveitis (MUV) Task Force.

Medical hypothesis, discovery & innovation ophthalmology journal

Intraretinal hyperreflective line: potential biomarker in various retinal disorders.

Review on the Use of Difluprednate in Inflammatory Eye Disorders: The Topical Steroid That Goes the Distance.

Efficacy and tolerability of subcutaneous repository corticotropin injection in refractory ocular inflammatory diseases.

Brain MRI White Matter Abnormalities in Pediatric Non-Infectious Uveitis.

Advanced healthcare materials

In Situ Crystallized Ceria-Vesicle Nanohybrid Therapeutic for Effective Treatment of Inflammatory Intraocular Disease.

Northern clinics of Istanbul

Rheumatic diseases detected in patients presenting with uveitis.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Cystoid macular edema after low-energy femtosecond-assisted cataract surgery.

Ocular Syphilis: The Resurgence of an Old Disease Experience of a Tertiary Centre in Portugal.

Diffuse preretinal infiltrates in a patient with orbital atypical T-cell lymphoproliferative infiltration masquerading posterior uveitis.

GMS ophthalmology cases

Tocilizumab for cystoid macular edema secondary to retinitis pigmentosa.

Isolated Intraocular Jarisch-Herxheimer Reaction Following Treatment for Syphilitic Chorioretinitis.

Frontiers in cellular neuroscience

Crystallin β-b2 promotes retinal ganglion cell protection in experimental autoimmune uveoretinitis.

Indian journal of ophthalmology

Intravitreal steroid implants in the management of noninfectious intermediate and posterior uveitis.

Are Peripapillary Hyperreflective Ovoid Mass-like Structures with an Elevated Optic Disc Still a Diagnosis Dilemma?

Recurrent ocular toxoplasmosis is associated with interferon-gamma deficiency possibly due to genetic origin.

BMJ open ophthalmology

Intravitreal Antibiotics versus Early Vitrectomy Plus Intravitreal Antibiotics for Postinjection Endophthalmitis: An IRIS® (Intelligent Research in Sight Registry) Analysis.

Ophthalmology. Retina

Unilateral Vogt-Koyanagi-Harada Disease With Two Distinct Choroidal Neovascular Membranes: A Case Report.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

The Clue to Neurosarcoidosis Through Outer Retina: A Rare Case of Cavernous Sinus Sarcoidosis Uncovered Through Signs of Previous Posterior Uveitis.

Human Ocular Toxoplasmosis in Romania: History, Epidemiology, and Public Health: A Narrative Review.

Microorganisms

Categories and Profiles of Uveitis in Vogt-Koyanagi-Harada Syndrome With Systemic Correlation: Inferences From a Tertiary Multispecialty Hospital.

Investigational new drugs

Clinical characteristics, treatment, and outcomes of pembrolizumab-induced uveitis.

Rheumatology (Oxford, England)

De novo manifestations during adalimumab treatment in Behçet's syndrome.

Uveitis following COVID-19 vaccination in the pediatric population: Experience at a tertiary referral hospital.

Development of Posterior Uveitis in Behçet Syndrome Patients with Vitreous Cells at Baseline.

Bilateral Anterior Uveitis in the Context of Concurrent HIV and Syphilis Co-infection.

Filgotinib in Active Noninfectious Uveitis: The HUMBOLDT Randomized Clinical Trial.

JAMA ophthalmology

Influence of gender on clinical presentation, management practices and outcomes of ocular syphilis.

Scientific reports

Romanian journal of ophthalmology

Toxoplasmosis in the outer retina.

Journal of clinical medicine

Assessment of Blood Flow Velocity in Retinal Vasculitis Using the Retinal Function Imager-A Pilot Study.

Not Always Toxoplasmosis: Active Retinochoroiditis Presumably Secondary to Herpes in Eyes with Hyperpigmented Retinochoroidal Previous Scars.

Frontiers in ophthalmology

Brief research report: ETS-1 blockade increases ICAM-1 expression in activated human retinal endothelial cells.

2023

Role of interleukin 1β and interleukin 10 variants on ocular toxoplasmosis in Brazilian individuals.

Frontiers in ophthalmology

The Spectrum of Presumed Tubercular Uveitis in a Referral Eye Clinic in Qatar.

Ophthalmic surgery, lasers & imaging retina

Long-Term Outcomes of Scleral-Sutured Fixated Secondary Intraocular Lenses in Patients With Uveitis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Ocular Syphilis in Patients With Nonreactive Rapid Plasma Reagin and Positive Treponemal Serologies: A Retrospective Observational Cohort Study.

Ocular Leptospirosis: Report of a Challenging Diagnosis.

Clinical Patterns of Sarcoidosis Patients with and without Uveitis: Insights from a Dutch Sarcoidosis Centre.

2023

A Case of Ocular Sarcoidosis Post-COVID-19 Vaccination.

Ocular oncology and pathology

Posterior Uveitis in Ocular-Involving Chronic Lymphocytic Leukemia and the Utility of Negative MYD88 L265P Testing in the Diagnosis.

Label-Free Imaging of Inflammation at the Level of Single Cells in the Living Human Eye.

Ophthalmology science