Raras
Buscar doenças, sintomas, genes...
Agenesia e aplasia do corpo uterino
ORPHA:180142CID-10 · Q51.0CID-11 · LB44.0DOENÇA RARA

Neoplasia, também chamada neoformação, neoplasma, neoplastia ou tumor, é uma proliferação celular local, sem que haja causa definida, podendo ocorrer de forma hereditária, dieta, estresse, obesidade, exposição desprotegida ao Sol, ou até exposição à toxinas do ambiente, como poluição, radiação ou até álcool. Havendo crescimento excessivo, ilimitado, progressivo e anormal que ocorre nos tecidos ou nos órgãos. Esta relação é irreversível e com tendência a perda de diferenciação celular. Estas afetam todos os organismos vivos, não se resumindo assim, somente ao reino animal.

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Introdução

O que você precisa saber de cara

📋

Condição rara caracterizada pela ausência congênita do corpo do útero, podendo estar associada à agenesia ou aplasia de outras estruturas reprodutivas. A apresentação clínica varia, mas a infertilidade é uma consequência comum.

🏥
SUS: Cobertura mínimaScore: 15%
CID-10: Q51.0
🇧🇷Dados SUS / DATASUS
PROCEDIMENTOS SIGTAP (5)
0202010503
Cariótipo — bandas G, Q ou Rgenetic_test
0202010600
Pesquisa de microdeleções/microduplicações por FISHlab_test
0202010694
Sequenciamento completo do exoma (WES)rehabilitation
0202010260
Dosagem de alfa-fetoproteína
0301070040
Atendimento em reabilitação — doenças raras
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Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa4
Últimos 10 anos200publicações
Pico202564 papers
Linha do tempo
2022Hoje · 2026🧪 2010Primeiro ensaio clínico📈 2025Ano de pico
Publicações por ano (últimos 10 anos)

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Genética e causas

O que está alterado no DNA e como passa nas famílias

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Os sinais que médicos procuram e os exames que confirmam

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Tratamento e manejo

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·Pré-clínico2
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Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Agenesia e aplasia do corpo uterino

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Publicações mais relevantes

Timeline de publicações
0 papers (10 anos)
#1

An exploratory study on the placental efficiency, histomorphometric characteristics, hormonal shifts, and oxidative stress in dromedary camels with dystocia.

Frontiers in veterinary science2026

The study investigated placental efficiency, histomorphometry, and hormonal concentrations (progesterone, estradiol 17β, and cortisol) alongside oxidative stress indicators (malondialdehyde (MDA) and total antioxidant capacity (TAC)) and performed correlation analyses among these parameters in eutocia, dystocia, and uterine inertia deliveries in dromedary camels. A total of 24 pregnant dromedary camels, aged 8-11 years, with an average body weight of 520 ± 75 kg, were categorized into three groups based on parturition outcome: the eutocia group (EG), n = 12; the dystocia group (DG), n = 5; and the uterine inertia group (UIG). n = 7. The results revealed significantly lower (p < 0.05) syncytiotrophoblast layer thickness, chorionic villi length and diameter, and syncytiotrophoblast layer integrity in dystocia deliveries. Additionally, the inflammatory cell infiltration was higher (p < 0.01) in DG than in UIG and EG. The placentas from EG had long, slender, and highly vascularized chorionic villi, while in DG placentas, the villi were shorter and atrophied. Progesterone concentrations were significantly higher (p < 0.01) in DG compared to UIG and EG. While DG had the lowest mean estradiol-17β concentration, EG had the highest. Moreover, MDA and TAC concentrations were lowest in the EG group, followed by the UIG group and then the DG group. Additionally, a positive correlation was found between chorionic villi diameter and placental efficiency, and between placental efficiency and vascular density. There were negative correlations among hormonal, antioxidant, placental efficiency, and histomorphometry parameters, as well as among these parameters and inflammatory cell infiltration. In conclusion, dystocia in camels was associated with hormonal dysregulation, presumably oxidative stress, and placental structural damage. However, for a definitive and powerful outline, further studies on large and more balanced populations are necessary in the future.

#2

Relationship Between VSELs, MUSE Cells and MSCs in Health and Disease.

Stem cell reviews and reports2026 Mar 04

A comprehensive understanding of how diverse adult stem cell populations function in harmony is crucial for maintaining homeostasis and ensuring the normal functioning of body tissues. Two types of stem cells in adult tissues have attracted attention, including very small embryonic-like stem cells (VSELs) and multi-lineage differentiating stress-enduring cells (MUSE), reported for the first time in 2006 and 2010, respectively. VSELs are pluripotent stem cells developmentally linked to the primordial germ cells, while MUSE cells, initially described as multipotent, are now being defined as having pluripotent characteristics and further differentiate into MSCs. VSELs are the most primitive, virtually immortal and pluripotent stem cells that survive lifelong in all tissues in small numbers and undergo asymmetrical divisions to give rise to tissue-specific progenitors of different sizes and fates. VSELs are 5-7 μm in size, spherical in shape, with a cell surface profile of LIN-CD133 + CD45- while MUSE cells are 10-15 μm in size, with abundant cytoplasm, horseshoe/bean-shaped nuclei, cytoplasmic OCT-4 and are CD45+, like hematopoietic stem cells. In the mouse uterus, VSELs undergo cyclic changes in response to circulatory hormones, regenerate both the epithelial and stromal compartments in an atrophied uterus (upon bilateral ovariectomy, in the absence of macrophages) and also upon chronic injury. Exposure to endocrine-disrupting chemicals disrupts the functions of VSELs and results in various pathologies, including endometrial cancer. The crucial role of dysfunctional VSELs resulting in cancer initiation, progression, metastasis and recurrence was recently discussed. On the other hand, multiple clinical trials have reported the potential of MUSE cells for ensuring regeneration upon transplantation. VSELs regenerate damaged and diseased tissues when a healthy paracrine support is provided by the transplanted MUSE cells/MSCs; however, remain elusive due to their small size and scarce nature. In summary, the view that MUSE cells phagocytose damaged cells and subsequently differentiate into the same cell type is fundamentally challenged and requires careful re-evaluation.

#3

Predictors of Procedural Pain in Office Hysteroscopy.

Medical science monitor : international medical journal of experimental and clinical research2026 Feb 23

BACKGROUND Various strategies have been explored to mitigate office hysteroscopy, including oral or local analgesia, modified cervical dilation techniques, and patient positioning, but there is no consensus on the most effective approach for office hysteroscopy performed for diagnostic purposes. Thus, we aimed to identify independent clinical and other factors associated with increased pain during office hysteroscopy to inform targeted pain reduction strategies. MATERIAL AND METHODS This prospective observational study included 102 women aged 18-70 years who underwent office hysteroscopy at a tertiary center between August and October 2020. Pain intensity was measured using a 10-cm visual analog scale (VAS). Vital signs were monitored before, during, and after the procedure. RESULTS The mean age of participants was 41.62±7.94 years. The mean VAS pain score during hysteroscopy was 4.91±2.97. Patients without a history of vaginal delivery reported significantly higher VAS scores than those with prior vaginal births (P<0.001). Retroverted uterus was associated with greater pain than anteverted or normally positioned uteri (P<0.001). Procedure duration showed a moderate positive correlation with pain (P<0.001), while body mass index (BMI) had a weak negative correlation (P=0.041), and the number of cesarean deliveries had a weak positive correlation with pain intensity (P=0.047). In multivariable analysis, retroverted uterus (P=0.007), longer procedure time (P=0.004), and absence of vaginal delivery (P=0.001) were independently associated with higher pain scores. CONCLUSIONS Retroverted uterine position, nulliparity, and longer procedure duration are independent predictors of increased pain during office hysteroscopy. Awareness of these risk factors allows clinicians to tailor their approach through enhanced pre-procedural counseling, optimized analgesia, and modifications in procedural technique to reduce patient discomfort.

#4

Effects of L-citrulline supplementation in the basal diet on reproductive performance, serum metabolites, and microbial community structure in Simmental cows.

Frontiers in microbiology2026

The experiment was designed to evaluate the influence of dietary supplementation with L-Citrulline (L-Cit) on reproductive outcomes, serum reproductive hormone profiles, ruminal and intestinal microbial communities, serum metabolites, and their metabolic associations in Simmental cows, thereby providing a theoretical basis for its application in ruminant production. All cows were screened by vaginal mucus microscopy (no pathogenic bacteria detected) and B-ultrasound examination (no ovarian cysts or uterine inflammation observed) to confirm the absence of reproductive disorders. A total of 240 multiparous Simmental cows, 3-4 years of age with an average body weight of 470 ± 15 kg, were randomly allocated into three groups of 80 animals each: a control group, Group I, and Group II. The control group received only the basal diet, whereas Group I and Group II were provided with the basal diet supplemented with 7 g/d and 14 g/d of L-Cit per cow, respectively. Day 0 of the trial was defined by the first intramuscular injection of prostaglandin (PG, 0.4 mg per cow), after which L-Cit supplementation commenced at 72-h intervals. On day 10, a second PG injection (0.4 mg per cow) was administered, and supplementation was discontinued on day 11. Estrus expression was monitored, and pregnancy was assessed on day 35 post-insemination using B-mode ultrasonography. During the experimental period, six cows were randomly selected from each group. Blood samples were collected from the coccygeal vein prior to the morning feeding on days 1 and 11 using plain tubes (without anticoagulant). The samples were centrifuged at 720 × g (approximately 3,000 rpm for 15 min) to separate the serum. The obtained serum was stored at -20 °C for subsequent analysis of reproductive hormones. In addition, blood, rumen fluid, and fecal samples were obtained 10 h after mounting to support untargeted metabolomic profiling and microbial community analysis. Compared with the control group, the estrus rate in experimental Group I increased by 12.5% (p < 0.05). In experimental Group II, serum concentrations of gonadotropin-releasing hormone (GnRH) and follicle-stimulating hormone (FSH) measured 10 h after cows accepted mounting rose by 15.79% (p < 0.05) and 35.71% (p < 0.01), respectively, relative to the control group. Analysis of 16S rRNA sequences revealed significant differences in ruminal microbial taxa, including Verrucomicrobiota, Lentisphaeria, Oligosphaeraceae, vadinBE97_g_norank, vadinBE97, Eubacterium_ruminantium_group, and Prevotellaceae_g_norank. In the intestine, significant differences were observed in Lachnospiraceae, Lachnospirales, Marvinbryantia, Desulfovibrionia, Desulfovibrionaceae, and Desulfobacterota. KEGG enrichment analysis based on Liquid Chromatography-Mass Spectrometry (LC-MS) data indicated upregulation of the arginine biosynthesis pathway in the experimental groups, whereas metabolites associated with the tricarboxylic acid (TCA) cycle were notably elevated in experimental Group I. Within the experimental framework, dietary supplementation with L-Cit combined with the two-shot PG synchronization protocol reshaped the ruminal microbial community structure of Simmental cows, improved glucose metabolic efficiency and xenobiotic degradation capacity, and promoted the synthesis and release of reproductive hormones. Consequently, estrus and conception rates were enhanced.

#5

A rare case of Mayer-Rokitansky-Küster-Hauser syndrome presenting with primary amenorrhea and chronic headaches: a case report.

International journal of surgery case reports2026 Jan

Primary amenorrhea is defined as the absence of menarche by age 13 without secondary sexual characteristics or by age 15 with them. Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is the second most common cause of primary amenorrhea after ovarian failure. This case highlights a 15-year-old female with MRKH syndrome type I presenting with chronic headaches. A 15-year-old female presented with primary amenorrhea and chronic frontal headaches. She reported non-foul-smelling white per vaginal discharge but denied visual disturbances, limb weakness, or systemic symptoms. Examination revealed normal secondary sexual characteristics, a blind vaginal pouch (0.5 cm), and a low body mass index of 17. Pelvic ultrasonography and MRI confirmed uterine agenesis with normal ovaries and no renal anomalies, consistent with MRKH syndrome. Brain MRI and hormonal profiles were normal, suggesting her headaches were likely nutritional and dehydration related, which improved with dietary optimization. A multidisciplinary team performed McIndoe vaginoplasty using a split-thickness skin graft, successfully creating a 9-cm neovagina. On follow-up, the patient demonstrated good neovaginal patency, maintained regular self-dilatation, and reported improved psychological well-being. MRKH syndrome is a congenital disorder characterized by the absence or underdevelopment of the uterus and upper vagina despite normal external genitalia and a 46,XX karyotype. It affects approximately 1 in 5000 females. Diagnosis is confirmed through imaging, with MRI being the most reliable modality. Although headaches are not commonly associated with MRKH, in this patient, they were likely due to undernutrition, dehydration, and psychological stress. Management of MRKH includes both nonsurgical (vaginal dilation) and surgical approaches. The McIndoe procedure, involving a skin graft to create a neovagina, has shown high success rates in improving sexual function and psychological well-being. Postoperative outcomes highlight the importance of a multidisciplinary approach. This case highlights a rare presentation of MRKH syndrome with primary amenorrhea and headache in a young adolescent. Although headaches may mislead diagnosis, imaging is vital for confirmation and exclusion of other causes. The patient improved following McIndoe vaginoplasty, emphasizing timely diagnosis, multidisciplinary care, and psychological support for optimal outcomes.

Publicações recentes

Ver todas no PubMed

📚 EuropePMCmostrando 198

2026

Effects of L-citrulline supplementation in the basal diet on reproductive performance, serum metabolites, and microbial community structure in Simmental cows.

Frontiers in microbiology
2026

An exploratory study on the placental efficiency, histomorphometric characteristics, hormonal shifts, and oxidative stress in dromedary camels with dystocia.

Frontiers in veterinary science
2026

A rare case of Mayer-Rokitansky-Küster-Hauser syndrome presenting with primary amenorrhea and chronic headaches: a case report.

International journal of surgery case reports
2026

Case Report: A patient with metastatic fumarate hydratase-deficient renal cell carcinoma associated with leiomyomatosis: real-world clinical insights on systemic therapy and liver-directed SBRT.

Frontiers in oncology
2026

Relationship Between VSELs, MUSE Cells and MSCs in Health and Disease.

Stem cell reviews and reports
2026

Predictors of Procedural Pain in Office Hysteroscopy.

Medical science monitor : international medical journal of experimental and clinical research
2026

Integrated microbiome and metabolome unveiled the effect of carbonate buffer mixture alleviating subacute rumen acidosis - Mediated endometritis in dairy goats.

Veterinary journal (London, England : 1997)
2026

Bilateral serous surface papillary borderline ovarian tumor with non-invasive implantation: a case report.

Frontiers in oncology
2026

An intraoperative localization method and a stepwise surgical technique for hysteroscopic treatment of International Federation of Gynecology and Obstetrics type 3 fibroid.

Fertility and sterility
2026

Chronic heat stress compromises egg production and quality parameters through changes in blood biochemistry and uterine gene expression in laying hens raised under cage-free environment.

Frontiers in physiology
2026

The Progesterone Challenge Test as a Functional Biomarker of Endometrial Cancer Risk: Results from a Prospective Feasibility Study.

Cancer prevention research (Philadelphia, Pa.)
2025

Fish bone foreign body causing rectal, uterine, and bladder perforation: a rare case report.

Frontiers in oncology
2025

Finding the hiding spots: uneven distribution of pathogenic Leptospira spp. in the bovine genital tract.

Frontiers in public health
2025

Perspectives from Hysterectomy Specimens on the Hidden Malignancy Risk in HSIL Patients with Surgical Margin Continuity.

Medicina (Kaunas, Lithuania)
2026

Predictive Accuracy of Ultrasound Biometry and Maternal Factors in Identifying Large-for-Gestational-Age Neonates at 30-34 Weeks.

Diagnostics (Basel, Switzerland)
2025

Higher consumption of sugar-sweetened beverages is associated with an increased risk of endometrial cancer: a prospective cohort study of 92,777 women from the UK Biobank.

Frontiers in public health
2025

Impact of BMI on basal LH in premenarcheal girls with idiopathic central precocious puberty.

Frontiers in endocrinology
2025

Body site-specific micro- and lactobiota in genitourinary infections during pregnancy.

Frontiers in cellular and infection microbiology
2025

Pubertal timing and incident uterine cancer in the Sister Study cohort.

International journal of cancer
2025

Machine learning-based prediction of clinical outcomes in cervical cancer using routine hematological indices: development and web implementation.

Frontiers in oncology
2025

CD155-based chimeric antigen receptor T cells: a promising immunotherapy for cervical and breast cancer.

Frontiers in immunology
2025

Robotic-assisted surgery in benign gynecology: single-center experience with 106 patients.

Frontiers in medicine
2025

Impact of combined hormonal contraceptives and metformin on metabolic syndrome in women with hyperandrogenic polycystic ovary syndrome and obesity: The COMET-PCOS randomized clinical trial.

PLoS medicine
2025

Maternal obesity in low-resource settings: a multicenter cohort study of labor and neonatal outcomes in Guinea.

Frontiers in medicine
2025

Catatropis indicus (Digenea: Notocotylidae) from ducks in Indonesia with a brief review of the genus Catatropis.

Parasites, hosts and diseases
2025

A comparative analysis of hysterectomy outcomes: robotic single-port vs. traditional transvaginal NOTES approaches.

Frontiers in medicine
2025

High BMI-attributable female-specific cancers: a comprehensive analysis of the global disease burden and trends from 1990 to 2021 and projections to 2040.

Frontiers in oncology
2025

Colonic metastasis of a huge soft uterine leiomyoma in a postmenopausal woman: a case report.

Frontiers in oncology
2025

Optimizing artificial insemination in goats: semen deposition site and vaginal mucus characteristics as predictive biomarkers.

Frontiers in veterinary science
2025

Obesity results in lower integrin expression in women with polycystic ovarian syndrome during the window of implantation.

Frontiers in endocrinology
2025

Global burden of ovarian and uterine cancers attributable to high body-mass index in 204 countries and territories, 1990-2021.

Frontiers in oncology
2025

Analysis of the characteristics of endometrial fluid samples in recurrent pregnancy loss patients based on 16S rRNA gene sequencing technology.

Frontiers in cellular and infection microbiology
2025

Temporal trends in cancer mortality attributable to high BMI in Asia: an age-period-cohort analysis based on GBD 1992-2021.

Frontiers in endocrinology
2025

Extra-Amniotic Bovine Foetus With Aplasia of the Posterior Body: A Case Report.

Reproduction in domestic animals = Zuchthygiene
2025

METTL3 Affects Endometrial Receptivity Through Modulation of P62-Mediated Autophagic Flux.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
2025

Clinical factors associated with uterine rupture in type II angular pregnancy: a 10-year single-institution retrospective study.

Frontiers in medicine
2025

Efficacy and Safety of Ormeloxifene Versus Conventional Hormonal Therapy in Women With Non-structural Abnormal Uterine Bleeding: A Systematic Review and Meta-Analysis.

Cureus
2025

Case Report: Uterine mesothelial cyst in a nulliparous woman-diagnostic and clinical challenges of a rare benign lesion.

Frontiers in medicine
2025

Ultrasonography-Based Measurements of Endometrial Thickness in Patients With p53 Abnormal Endometrial Carcinomas.

Obstetrics and gynecology
2025

Serum 25 (OH) D levels and risk of female-specific cancer in premenopausal women: a prospective study.

Frontiers in nutrition
2025

Hysteroscopic surgery for treating intramural fibroids at the cesarean scar area: a case report and literature review.

Frontiers in medicine
2025

Corpus luteum number and maternal circulatory adaptation from early pregnancy onwards: the Rotterdam Periconception Cohort (Predict Study).

Human reproduction (Oxford, England)
2025

Multimodal imaging features of high-grade endometrial stromal sarcoma with pulmonary and nodal metastases: a case report and literature review.

Frontiers in medicine
2025

Burden and trends of ovarian and uterine cancer due to high body mass index from 1990 to 2021: an age-period-cohort study based on the GBD 2021, and projections through 2036.

Frontiers in oncology
2025

Global burden of cancer attributable to high BMI (1990-2031): a multidimensional analysis based on GBD and Mendelian randomization.

Frontiers in nutrition
2025

Case Report: Unilateral uterine torsion in a non-pregnant Siberian-Husky-clinical insights and implications for reproductive management.

Frontiers in veterinary science
2025

Nomogram to predict live birth in infertile women with adenomyosis undergoing IVF/ICSI treatment: a retrospective cohort study.

Frontiers in endocrinology
2025

Global burden of polycystic ovary syndrome, uterine cancer and diabetes mellitus type 2 among women of childbearing age: trends in incidence, prevalence, mortality, and disability-adjusted life-years from 1990 to 2021.

Frontiers in medicine
2025

Case Report: Clinical, laboratory, and pathological findings in cows with osteomyelitis of the ribs and sternum and endocarditis valvularis thromboticans.

Frontiers in veterinary science
2025

Examination of the proposed relationships between cyclic menstruation and human reproduction.

Frontiers in global women's health
2025

Case Report: Strangulated intestinal obstruction due to chronic migration of an intrauterine device (IUD): a 30-year latent complication.

Frontiers in medicine
2025

Clinical utility of various liquid biopsy samples for the early detection of ovarian cancer: a comprehensive review.

Frontiers in oncology
2025

Efficiency of laparoscopic artificial insemination in goats: impact of laparoscopic insemination sheath needle design.

Frontiers in veterinary science
2025

High frequency of sexually transmitted infections in patients with precancerous cervical lesions in Brazil.

Frontiers in public health
2025

Factors Associated With the Success of External Cephalic Version for Breech Presentation: A Retrospective Study.

Cureus
2025

Vesicouterine fistula with vesical calculi secondary to IUD migration: a case report.

Contraception and reproductive medicine
2025

Robotic radical trachelectomy in early stage cervical cancer.

Journal of robotic surgery
2025

Causal impact of obesity class stratification and endometrial cancer subtypes: an integrated Mendelian randomization and Global Burden of Disease Study 2021 analysis.

International journal of surgery (London, England)
2025

Transvaginal flexible endoscopy for bleeding arteriovenous malformation hemostasis near a vesico-rectovaginal fistula.

VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy
2025

Comparison of maternal and neonatal outcomes between general anesthesia and combined spinal-epidural anesthesia in cesarean delivery for pregnancy complicated with placenta previa.

BMC anesthesiology
2025

Regulatory element map of sheep reproductive tissues: functional annotation of tissue-specific strong active enhancers.

Frontiers in veterinary science
2025

MRI assessment of sacral injury location and analysis of influencing factors after high-intensity focused ultrasound ablation for patients with uterine fibroids.

Frontiers in physiology
2025

Effects of cold environment exposure on female reproductive health and its regulatory mechanisms.

Frontiers in genetics
2025

Cloning, bioinformatics analysis, and expression of the ubiquitin 2 (ubq-2) gene from the dog roundworm Toxocara canis.

Frontiers in veterinary science
2025

Sophoraflavanone G as an ectosteric inhibitor of cathepsin K attenuates ovariectomy-induced bone loss by suppressing bone resorption.

Phytomedicine : international journal of phytotherapy and phytopharmacology
2025

Association of composite dietary antioxidant index and endometriosis risk in reproductive-age women: a cross-sectional study using big data-machine learning approach.

Frontiers in nutrition
2025

An aerobe exercise intervention for optimizing metabolic, cardiovascular and immune status: protocol of an intervention study with a multi-systemic approach for women with unexplained recurrent pregnancy loss.

Frontiers in medicine
2025

Insomnia and Female Reproductive Diseases: A Cross-Sectional and Mendelian Randomization Study.

International journal of women's health
2025

Correlation between uterine microbiota and pregnancy outcomes of embryo transfer in overweight and obese women.

Frontiers in cellular and infection microbiology
2024

The effect of the number of endometrial CD138+ cells on the pregnancy outcomes of infertile patients in the proliferative phase.

Frontiers in endocrinology
2025

Transfer of the Oral Gonadotropin-Releasing Hormone Receptor Antagonist Relugolix Into Breast Milk of Healthy Lactating Women.

Pharmacology research &amp; perspectives
2025

Hypothyroidism Alters Uterine Kisspeptin System and Activity Modulators in Cyclic Rats.

International journal of molecular sciences
2024

Abnormal Uterine Bleeding Among Rural Adolescent Schoolgirls: A Cross-Sectional Study.

Medicina (Kaunas, Lithuania)
2025

Malignant peripheral nerve sheath tumour (MPNST) of the cervix: differential diagnosis and a favourable oncological outcome with multimodality treatment.

BMJ case reports
2025

The reproductive tract microbiome in women with polycystic ovary syndrome and across different menstrual cycle phases.

Human reproduction (Oxford, England)
2024

Primary uterine non-Hodgkin's lymphoma:a rare case report and review of the literature.

Frontiers in oncology
2025

Lichong decoction improves inflammatory microenvironment and alleviates fibrosis in uterine leiomyoma via targeting CXCL8.

Journal of ethnopharmacology
2024

Protracted maternal malnutrition induces aberrant changes in maternal uterine artery hemodynamics and the metabolic profiles of the dam and neonate.

Frontiers in physiology
2024

Transcriptomic alterations in the ovine caruncular endometrium due to imbalanced nutrition and FSH-induced ovarian hyperstimulation.

BMC genomics
2024

Prognostic and clinicopathological significance of survivin in gynecological cancer.

Oncology reviews
2025

Reproductive outcomes after surgical resection of isthmocele in secondary infertility.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
2024

A new species of Australotaenia (Cestoda: Proteocephalidae) from a hylid frog in Australia.

Zootaxa
2025

The uterine artery resistivity index is affected by embryo resorption rate at canine pregnancy diagnosis.

Theriogenology
2024

The novel estrogen receptor beta agonist EGX358 and APOE genotype influence memory, vasomotor, and anxiety outcomes in an Alzheimer's mouse model.

Frontiers in aging neuroscience
2024

Laparoscopic myomectomy without uterine manipulator for maintaining endometrial cavity integrity.

Heliyon
2024

From patient classification to optimized treatment in ART: the AMPLITUDE Delphi consensus.

Frontiers in reproductive health
2024

Identifying key predictors for uterine manipulator use in robotic simple hysterectomy: a retrospective cohort analysis.

Frontiers in medicine
2024

Creation of a Neovagina with Single Staged Uterine Anastomosis.

CRSLS : MIS case reports from SLS
2024

Long-term obstetric, perinatal, and surgical complications in singleton pregnancies following previous cesarean myomectomy: a retrospective multicentric study.

Frontiers in surgery
2024

Evodiamine suppresses endometriosis development induced by early EBV exposure through inhibition of ERβ.

Frontiers in pharmacology
2024

Leonurine: a comprehensive review of pharmacokinetics, pharmacodynamics, and toxicology.

Frontiers in pharmacology
2024

A gluten-free diet for endometriosis patients lacks evidence to recommend it.

AJOG global reports
2024

True uterus didelphys in she-camel: a case report and review of literature.

Frontiers in veterinary science
2024

Pelvic ultrasound and pubertal attainment in girls with sexual precocity: the pivotal role of uterine volume in predicting the timing of menarche.

Frontiers in endocrinology
2024

Puberty in girls with Prader-Willi syndrome: cohort evaluation and clinical recommendations in a Latin American tertiary center.

Frontiers in endocrinology
2024

Effects of food restriction on toxicological parameters in juvenile rats.

The Journal of toxicological sciences
2024

Hydrogen sulfide and its role in female reproduction.

Frontiers in veterinary science
2024

Transgenic mice applications in the study of endometriosis pathogenesis.

Frontiers in cell and developmental biology
2024

Adenomyosis and Abnormal Uterine Bleeding: Review of the Evidence.

Biomolecules
2024

Establishment of the uterine microbiome following artificial insemination in virgin heifers.

Frontiers in microbiology
2024

Localization of Catecholaminergic Neurofibers in Pregnant Cervix as a Possible Myometrial Pacemaker.

International journal of molecular sciences
2024

[Expert consensus on the diagnosis and treatment of obstructive sleep apnea in women].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
2024

Working together with people with intellectual disability to make a difference: a protocol for a mixed-method co-production study to address inequities in cervical screening participation.

Frontiers in public health
2024

The HPV viral regulatory mechanism of TLRs and the related treatments for HPV-associated cancers.

Frontiers in immunology
2024

The effectiveness of relugolix compared with leuprorelin for preoperative therapy before laparoscopic myomectomy in premenopausal women, diagnosed with uterine fibroids: protocol for a randomized controlled study (MyLacR study).

Trials
2024

Endometrium development patterns and BMI groups among in vitro fertilization patients; prognostic aspects.

Frontiers in endocrinology
2024

Extracellular vesicles in endometriosis: role and potential.

Frontiers in endocrinology
2024

Oxytocin infusion dose-response to maintain uterine tone in obese elective cesarean patients: a randomized controlled trial.

Frontiers in pharmacology
2024

Comparative study of second-line labor induction methods in patients with unfavorable cervix after first-line low-dose oral misoprostol.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
2024

Pituitary Stalk Interruption Syndrome with Excessive Height Growth Combined with Congenital Absence of the Uterus and Ovaries: A Rare Case Report and Review of the Literature.

Diabetes, metabolic syndrome and obesity : targets and therapy
2024

Ovarian tissue biopsy for cryopreservation by vaginal natural orifice transluminal endoscopic surgery: a new approach for a minimal invasive ovarian biopsy.

Fertility and sterility
2024

Cytokine profile in peripheral blood mononuclear cells differs between embryo donor and potential recipient sows.

Frontiers in veterinary science
2024

Decidual γδT cells of early human pregnancy produce angiogenic and immunomodulatory proteins while also possessing cytotoxic potential.

Frontiers in immunology
2024

Evaluating the safety and efficacy of cryopreserved ovarian tissue transplantation in leukemia patients with different bone marrow remission status using xenotransplantation.

Frontiers in endocrinology
2024

Clandestine abortion resulting in uterine perforation and a retained foreign body led to generalized peritonitis: a case report from Lilongwe, Malawi.

AJOG global reports
2024

Vaginal dysbiosis seems associated with hrHPV infection in women attending the Dutch Cervical Cancer Screening Program.

Frontiers in cellular and infection microbiology
2024

Multichannel mapping of in vivo rat uterine myometrium exhibits both high and low frequency electrical activity in non-pregnancy.

Scientific reports
2024

Safety of Oral Carica papaya L. Leaf 10% Ethanolic Extract for Acute and Chronic Toxicity Tests in Sprague Dawley Rats.

Toxics
2024

Role of the gut microbiota in the pathogenesis of endometriosis: a review.

Frontiers in microbiology
2024

Analysis of clinical data of different endometrial pathological types in perimenopausal women with abnormal uterine bleeding.

Frontiers in oncology
2024

Pineal cysts may promote pubertal development in girls with central precocious puberty: a single-center study from China.

Frontiers in endocrinology
2024

Mini review: Asymmetric Müllerian duct development in the chicken embryo.

Frontiers in cell and developmental biology
2023

PECULIARITIES OF THE ORGANS OF THE REPRODUCTIVE SYSTEM OF WOMEN OF REPRODUCTIVE AGE WITH LIVER DYSFUNCTION UNDER THE INFLUENCE OF EXOGENOUS POLLUTANTS.

Georgian medical news
2024

Acute retinal necrosis in a patient with cervical malignant tumor treated with sintilimab: a case report and literature review.

Frontiers in immunology
2024

Robotic-assisted single-site abdominal cerclage in the bicornuate uterus patient with cervical insufficiency.

Fertility and sterility
2023

The influence of the combined impairments and apical mesh surgery on the biomechanical behavior of the pelvic floor system.

Frontiers in bioengineering and biotechnology
2023

Role of gonadotropin-releasing hormone 2 and its receptor in human reproductive cancers.

Frontiers in endocrinology
2024

Laparoscopic Evaluation of the Reproductive Tract in Two Female Polar Bears (Three Procedures) (Ursus maritimus).

Life (Basel, Switzerland)
2023

[Analysis of the maternal and fetal adverse outcomes of 154 pregnant women with cesarean section in the second stage of labor].

Zhonghua fu chan ke za zhi
2024

Phenotypic, endocrinological, and metabolic effects of zearalenone exposure and additive effect of heat stress in prepubertal female pigs.

Journal of thermal biology
2023

Antibiotic treatment of women with isolated intrapartum fever vs clinical chorioamnionitis: maternal and neonatal outcomes.

American journal of obstetrics and gynecology
2023

Uterine dynamics, blood profiles, and electronic fetal monitoring of primiparous and multiparous bitches classified according to their weight.

Frontiers in veterinary science
2023

Xanthogranulomatous inflammation of the female genital tract: An 11-year single institutional study of 40 cases.

Annals of diagnostic pathology
2023

Overlapping imaging features between miscarriage of a low-lying gestational sac and cervical ectopic pregnancy.

Australasian journal of ultrasound in medicine
2023

Exosomes: potential diagnostic markers and drug carriers for adenomyosis.

Frontiers in pharmacology
2024

Advantage of ostarine over raloxifene and their combined treatments for muscle of estrogen-deficient rats.

Journal of endocrinological investigation
2023

Postpartum vaginal discharge score is associated with genetic traits, postpartum fertility phenotypes, metabolic status, and overall reproductive performance in seasonal-calving pasture-based dairy cows.

Journal of dairy science
2023

Systematic review of the association between talc and female reproductive tract cancers.

Frontiers in toxicology
2023

The role of Th17 and Treg cells in normal pregnancy and unexplained recurrent spontaneous abortion (URSA): New insights into immune mechanisms.

Placenta
2023

Extracellular Vesicles-mediated recombinant IL-10 protects against ascending infection-associated preterm birth by reducing fetal inflammatory response.

Frontiers in immunology
2023

A study of the pharmacokinetics and pharmacodynamics of oxytocin at elective caesarean delivery.

Anaesthesia
2023

Phthalate exposure and risk of ovarian dysfunction in endometriosis: human and animal data.

Frontiers in cell and developmental biology
2023

The abscopal effect of immune-radiation therapy in recurrent and metastatic cervical cancer: a narrative review.

Frontiers in immunology
2023

Normalization of puberty and adult height in girls with Turner syndrome: results of the Swedish Growth Hormone trials initiating transition into adulthood.

Frontiers in endocrinology
2023

Immune responses in the uterine mucosa: clues for vaccine development in pigs.

Frontiers in immunology
2023

Longitudinal assessment of spiral and uterine arteries in normal pregnancy using novel ultrasound tool.

Ultrasound in obstetrics &amp; gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
2023

Protective effects of lycopene against zearalenone-induced reproductive toxicity in early pregnancy through anti-inflammatory, antioxidant and anti-apoptotic effects.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
2023

Boost modalities in cervical cancer: dosimetric comparison between intracavitary BT vs. intracavitary + interstitial BT vs. SBRT.

Radiation oncology (London, England)
2023

The Impacts of Supplemental Protein during Development on Amino Acid Concentrations in the Uterus and Pregnancy Outcomes of Angus Heifers.

Animals : an open access journal from MDPI
2023

Reproductive outcomes and risk factors of women with septate uterus after hysteroscopic metroplasty.

Frontiers in endocrinology
2023

ESGO/ESTRO/ESP Guidelines for the management of patients with cervical cancer - Update 2023.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
2023

Polycystic ovary syndrome and body image concerns during adolescence.

Journal of pediatric nursing
2023

CD44 targeted delivery of oncolytic Newcastle disease virus encapsulated in thiolated chitosan for sustained release in cervical cancer: a targeted immunotherapy approach.

Frontiers in immunology
2023

Nomogram for predicting the risk of preterm delivery after IVF/ICSI treatment: an analysis of 11513 singleton births.

Frontiers in endocrinology
2023

Correlation between inflammatory marker and lipid metabolism in patients with uterine leiomyomas.

Frontiers in medicine
2023

The effects of obesity and insulin dysregulation on mare reproduction, pregnancy, and foal health: a review.

Frontiers in veterinary science
2023

Differential diagnosis of precocious puberty in girls during the COVID-19 pandemic: a pilot study.

BMC pediatrics
2023

Sexually dimorphic pubertal development and adipose tissue kisspeptin dysregulation in the obese and preeclamptic-like BPH/5 mouse model offspring.

Frontiers in physiology
2023

Uterine torsion in twin pregnancy with complete bicorporeal uterus, double cervix, longitudinal non-obstructing vaginal septum - a case report.

Frontiers in surgery
2023

The emerging role of neutrophil extracellular traps in endometritis.

Frontiers in immunology
2023

Efficacy of different treatment protocols for endometritis in Camelus dromedarius.

Frontiers in veterinary science
2023

Impact of Suspected Preterm Labor during Pregnancy on Cardiometabolic Profile and Neurodevelopment during Childhood: A Prospective Cohort Study Protocol.

Diagnostics (Basel, Switzerland)
2023

Adverse effect of assisted reproductive technology-related hyperoestrogensim on the secretion and absorption of uterine fluid in superovulating mice during the peri-implantation period.

Frontiers in endocrinology
2023

A CRISPR/Cas9-engineered mouse carrying a conditional knockout allele for the early growth response-1 transcription factor.

Genesis (New York, N.Y. : 2000)
2022

Placental Maternal Vascular Malperfusion is Associated with Prepregnancy and Early Pregnancy Maternal Cardiovascular and Thrombotic Profiles.

Reproductive medicine (Basel, Switzerland)
2023

Pharmacological and toxicological studies of a novel goserelin acetate extended-release microspheres in rats.

Frontiers in pharmacology
2023

Modulating Morphological and Redox/Glycative Alterations in the PCOS Uterus: Effects of Carnitines in PCOS Mice.

Biomedicines
2023

Female reproductive tract-organ axes.

Frontiers in immunology
2023

Case report: Highly differentiated endometrial adenocarcinoma that collided with uterine cervical carcinosarcoma.

Frontiers in medicine
2023

Effects of maternal characteristics and medical history on first trimester biomarkers for preeclampsia.

Frontiers in medicine
2023

Isolated para-aortic nodal recurrence after treatment of early stage cervical carcinoma.

Gynecologic oncology
2022

Effects of labor induction in obesity with delayed pregnancy: A retrospective study based on Chinese obese primipara.

Frontiers in endocrinology
2022

Epidemiological analysis of hydrometra and its predictive value in gynecological tumors.

Frontiers in oncology
2022

Messenger roles of extracellular vesicles during fertilization of gametes, development and implantation: Recent advances.

Frontiers in cell and developmental biology
2023

Isolated Bacteria from the Uteri of Camels with Different Reproductive Backgrounds: A Study on Sampling Methodology, Prevalence, and Clinical Significance.

Veterinary sciences
2023

Physical and Mental Effects of Foot Baths Among Women in Labor: Protocol for a Pre-Post Test Experimental Design.

JMIR research protocols
2022

Primary amenorrhea in a 17-year and 6-month old girl due to celiac disease: A case report.

Annals of medicine and surgery (2012)
2023

Short-term consumption of the mycotoxin zearalenone by pubertal gilts causes persistent changes in the histoarchitecture of reproductive tissues.

Journal of animal science
2022

Potential of Lactobacillus acidophilus to modulate cytokine production by peripheral blood monocytes in patients with endometriosis.

Iranian journal of microbiology
2022

Non-tumoral uptake of 68Ga-FAPI-04 PET: A retrospective study.

Frontiers in oncology
2023

Evaluation of clinical and subclinical endometritis impacts on the reproductive performance and milk production of dairy cows in Brazilian herds.

Reproduction in domestic animals = Zuchthygiene
2022

Acute and sub-acute toxicity evaluation of dihydro-p-coumaric acid isolated from leaves of Tithonia diversifolia Hemsl. A. Gray in BALB/c mice.

Frontiers in pharmacology
2022

First-Trimester Biochemical Serum Markers in Female Kidney Transplant Recipients-The Impact of Graft Function.

International journal of environmental research and public health
2023

A mouse model mimicking gender-affirming treatment with pubertal suppression followed by testosterone in transmasculine youth.

Human reproduction (Oxford, England)
2022

Re-evaluation of mouse models of endometriosis for pathological and immunological research.

Frontiers in immunology
2022

Overall adjustment acupuncture improves osteoporosis and exerts an endocrine-modulating effect in ovariectomized rats.

Frontiers in endocrinology
2022

Selenium supplementation and pregnancy outcomes.

Frontiers in nutrition
2022

Yin Huo Tang, a traditional Chinese herbal formula, relives ovariectomy and empty bottle stimulation-induced menopause-like symptoms in mice.

Frontiers in endocrinology
2022

Ultrasonographic changes in fetal gastrointestinal motility during the last ten days before parturition in dogs.

Frontiers in veterinary science
2022

Epidemiological trends of female breast and gynecologic cancers in adolescents and young adults in China from 1990 to 2019: Results from the Global Burden of Disease Study 2019.

Frontiers in oncology
2022

Bacterial DNA involvement in carcinogenesis.

Frontiers in cellular and infection microbiology
2022

Ovariectomy-induced hormone deprivation aggravates Aβ1-42 deposition in the basolateral amygdala and cholinergic fiber loss in the cortex but not cognitive behavioral symptoms in a triple transgenic mouse model of Alzheimer's disease.

Frontiers in endocrinology
2022

Membrane estrogen signaling in female reproduction and motivation.

Frontiers in endocrinology
2022

Effects of uteroplacental insufficiency on growth-restricted rats with altered lung development: A metabolomic analysis.

Frontiers in pediatrics
2023

Comparison of two different methods for cervicovaginal reconstruction: a long-term follow-up.

International urogynecology journal
2022

Nomogram for the cumulative live birth in women undergoing the first IVF cycle: Base on 26, 689 patients in China.

Frontiers in endocrinology
2022

Antiosteoporosis and bone protective effect of dieckol against glucocorticoid-induced osteoporosis in rats.

Frontiers in endocrinology
2022

Breast and cervical cancer screening adherence in Jiangsu, China: An ecological perspective.

Frontiers in public health

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. An exploratory study on the placental efficiency, histomorphometric characteristics, hormonal shifts, and oxidative stress in dromedary camels with dystocia.
    Frontiers in veterinary science· 2026· PMID 41847364mais citado
  2. Relationship Between VSELs, MUSE Cells and MSCs in Health and Disease.
    Stem cell reviews and reports· 2026· PMID 41779358mais citado
  3. Predictors of Procedural Pain in Office Hysteroscopy.
    Medical science monitor : international medical journal of experimental and clinical research· 2026· PMID 41725184mais citado
  4. Effects of L-citrulline supplementation in the basal diet on reproductive performance, serum metabolites, and microbial community structure in Simmental cows.
    Frontiers in microbiology· 2026· PMID 41853720mais citado
  5. A rare case of Mayer-Rokitansky-K&#xfc;ster-Hauser syndrome presenting with primary amenorrhea and chronic headaches: a case report.
    International journal of surgery case reports· 2026· PMID 41815999mais citado
  6. Endometrial immune cell profile at the time of frozen embryo transfer as prognostic indicator of live birth.
    Front Immunol· 2026· PMID 41869347recente
  7. miRNA/mRNA analysis of increased TGF-β pathways drive epithelial-mesenchymal transition and regulatory T cell differentiation.
    Front Immunol· 2026· PMID 41869342recente
  8. Electroacupuncture may improve endometrial receptivity in controlled ovarian hyperstimulation mice by activating AVP neurons.
    Front Endocrinol (Lausanne)· 2026· PMID 41809531recente
  9. Co-delivery of endometrial mesenchymal stem cells and macrophages with an electrospun patch suppresses endometrial fibrosis via IL-10 related signaling.
    Front Immunol· 2026· PMID 41798931recente
  10. Vaginal and endometrial microbiota dysbiosis in patients with chronic endometritis: a systematic review and meta-analysis.
    Front Cell Infect Microbiol· 2026· PMID 41798744recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:180142(Orphanet)
  2. MONDO:0015844(MONDO)
  3. GARD:20185(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Q55785767(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Agenesia e aplasia do corpo uterino
Compêndio · Raras BR

Agenesia e aplasia do corpo uterino

ORPHA:180142 · MONDO:0015844
CID-10
Q51.0 · Agenesia e aplasia do útero
CID-11
MedGen
UMLS
C5230999
Wikidata
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