A síndrome de dor regional complexa, também conhecida como distrofia simpático-reflexa, síndrome da dor regional complexa (SDRC) e síndrome dolorosa complexa regional (SDCR), descreve uma série de condições dolorosas que são caracterizadas por uma dor regional contínua que é aparentemente desproporcional no tempo ou grau em relação ao curso actual de qualquer trauma conhecido ou outra lesão. Geralmente começa num membro, manifesta-se como dor extrema, inchaço, amplitude limitada de movimento e alterações na pele e nos ossos. Pode afetar inicialmente um membro e depois se espalhar por todo o corpo; 35% das pessoas afetadas relatam sintomas em todo o corpo. Existem dois subtipos. É possível ter os dois tipos.
Introdução
O que você precisa saber de cara
A Algodistrofia, também conhecida como Síndrome Dolorosa Regional Complexa tipo 1, é uma condição crônica caracterizada por dor intensa, inchaço e alterações na pele e temperatura de um membro, geralmente após uma lesão ou fratura. Os sintomas podem incluir sensibilidade extrema ao toque, rigidez articular e alterações na coloração e textura da pele afetada.
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
1/2k
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Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Linha do tempo da pesquisa
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Genética e causas
O que está alterado no DNA e como passa nas famílias
Nenhum gene associado encontrado
Os dados genéticos desta condição ainda estão sendo catalogados.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
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🇧🇷 Atendimento SUS — Algodistrofia
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Publicações mais relevantes
The nonhallucinogenic ketamine metabolite (2R,6R)-hydroxynorketamine is a novel analgesic in animal models of pain.
Current treatment options for acute and chronic pain provide limited efficacy and safety. There is an urgent need to develop drugs with new, non-opioid treatment strategies that produce fewer adverse consequences. Preclinical evidence across multiple models of acute and chronic pain demonstrate that (2R,6R)-Hydroxynorketamine [(2R,6R)-HNK], a nonhallucinogenic metabolite of ketamine, promotes potent and long-lasting analgesic effects. This review summarizes the growing evidence for the analgesic action of (2R,6R)-HNK in rodent models of acute and chronic pain. (2R,6R)-HNK produces antinociceptive effects in studies using standard tests for acute pain such as the hot plate test, although not in all studies, as well as reversal of mechanical hypersensitivity in models of acute pain like the carrageenan model (inflammatory pain). However, the most consistent anti-allodynic effects are seen in animal models aimed at mimicking chronic pain conditions, such as models of neuropathic pain (Spared Nerve Injury and Chemotherapy-induced peripheral neuropathy), low-back pain (disc puncture), complex regional pain syndrome type-1 (tibial fracture) and chronic primary pain (low-frequency percutaneous electrical nerve stimulation). Unlike ketamine, doses of (2R,6R)-HNK that counteract pain hypersensitivity do not cause sedation, dissociation, or sustain self-administration associated with abuse liability. Furthermore, distinct pharmacological effects of (2R,6R)-HNK, longer functional duration of action, non-opioid-mediated analgesia, and glutamatergic-mediated mechanisms, may distinguish (2R,6R)-HNK from ketamine and other analgesic drugs and contribute to the treatment of acute and chronic pain.
How postmenopausal osteoporosis influences epidemiology and clinical features of CRPS-1.
This study aimed to investigate the relationship between Osteoporosis (OP) and Complex Regional Pain Syndrome type 1 (CRPS-1), in the hypothesis that OP can influence the epidemiological and clinical features of CRPS-1. From March 2013 to May 2024, consecutive patients newly diagnosed with CRPS-1 were recruited. Demographic and clinical variables were collected in a standardised fashion. Univariate analyses and multivariate linear regression models were used to investigate the sample. We enrolled 425 patients, mostly females (70.1%), more than half (52.2%) with a fracture as the inciting event. A previous OP diagnosis was found in 113 patients (26.6%). Variables significantly associated with OP were female gender, hand localisation, fracture as the inciting event, and a more severe CRPS-1. A fracture in patients with OP seems to trigger CRPS-1 mainly in women in the first decade after menopause, while in males and in older women a weaker association was observed. Multivariate analysis showed a correlation between OP and a more severe CRPS-1 (p = 0.014). A higher incidence of OP was observed more frequently in women with CRPS-1 in the first decade after menopause. This result could be driven by the proinflammatory cytokines increase observed in the early menopause, inducing both a faster systemic bone loss and an "inflammatory milieu" acting as a predisposing factor for CRPS-1 onset and a more severe disease.
Sex differences in pain-related behaviour and the endocannabinoid system following hind limb ischemia-reperfusion injury.
Ischemia-reperfusion (I/R) injury causes tissue damage in organ transplantation, stroke and myocardial infarction, and underlies chronic wound formation. The endocannabinoid system (ECS) is involved in pain modulation, maintenance of skin homeostasis, and ischemic preconditioning, an endogenous protective mechanism against I/R-mediated damage. The rodent hind limb I/R model is a model of chronic post-ischemia pain, complex regional pain syndrome-type 1 (CRPS-1), and a potential model of wound-related pain. Research into sex differences in pain-related behaviour and the ECS following hind limb I/R injury is limited. Herein, we aimed to characterise the pain-related behavioural phenotype and ECS in male and female Sprague-Dawley rats following I/R injury. Mechanical, cold and heat hypersensitivity were quantified in both hind paws at baseline and up to 29 days post-unilateral hind limb I/R injury (or sham control). Endocannabinoid and N-acylethanolamine levels, and expression of ECS-related genes, were quantified in pain-related brain regions and spinal cord 30 days post-I/R injury. Persistent mechanical and transient cold hypersensitivity were observed in male rats following I/R, but were not robustly present in females. In female rats, I/R induced significantly higher levels of N-palmitoylethanolamide in the thalamus, compared with sham and male I/R counterparts, and significantly lower levels of 2-AG in the contralateral amygdala, compared with sham counterparts. There were no I/R-induced alterations in expression of ECS genes at 30 days post-IR. These results indicate sex differences in pain-related behaviour and in the ECS following I/R injury, and provide a solid foundation for future studies targeting the endocannabinoid system for therapeutic benefit. PERSPECTIVE: This article presents an investigation into sex differences following hind limb I/R injury, and associated alterations in the endocannabinoid system. This research could inform future research into novel endocannabinoid system-targeting treatment strategies for the management of pain in conditions affected by I/R injury including chronic regional pain syndrome type-1, and chronic wounds.
MRI has limited accuracy in diagnosing complex regional pain syndrome Type 1 - a systematic review of the literature.
To review the current body of research on the diagnostic accuracy of magnetic resonance imaging (MRI) in Complex Regional Pain Syndrome (CRPS) Type 1. A systematic search was conducted across MEDLINE, Embase, Cochrane, Scopus, and Web of Science from their inception to September 2023, following PRISMA guidelines. Risk of bias was assessed for all included studies, sensitivity and specificity values were extracted from studies with comparative data. Fifteen studies published between 1991 and 2022, involving 562 patients (353 with CRPS Type 1 and 209 controls), were included in the qualitative synthesis. Four comparative studies provided sufficient data to calculate diagnostic performance. Reported sensitivity ranged from 6 % to 91 %, and specificity from 50 % to 100 %, demonstrating substantial heterogeneity. Bone marrow edema was the most frequently reported MRI feature, particularly in early disease stages. Most studies had a high risk of bias due to inconsistent diagnostic criteria, non-standardized imaging protocols, and incomplete clinical and demographic reporting. Comparative studies showed inconsistent diagnostic performance, while non-comparative studies revealed variable MRI findings across different CRPS Type 1 presentations. MRI is not accurate in diagnosing CRPS Type 1, with a lack of consistent findings across studies. While it may assist in differential diagnosis, its utility as a standalone diagnostic tool is very limited. MRI can be used as an adjunct to clinical assessment for CRPS Type 1 to exclude alternative diagnoses and guide management but lacks the diagnostic accuracy to diagnose CRPS Type 1.
Examining the effects of race/ethnicity and other factors on outcomes of care for complex regional pain syndrome type 1 in the United States.
Complex regional pain syndrome is a chronic pain disorder marked by symptoms such as swelling, impaired motor function, and sympathetic dysfunction. Our primary objective was to determine the total number of complex regional pain syndrome type 1 (CRPS-1) emergency department (ED) visits and hospitalizations by race/ethnicity, as well as to assess sex and age distributions by race/ethnicity. Secondary objectives were to examine whether race/ethnicity, as well as select characteristics, are associated with hospitalization and longer length of stay. We completed a cross-sectional study of adults (19+ years) using acute and inpatient care data from the 2020 Nationwide Emergency Department Sample and the National Inpatient Sample. The overall rate of CRPS-1 diagnosis among ED visits and hospitalizations was 0.02% and 0.04%, respectively. Most CRPS-1 care was provided to White (ED: 83.1%; inpatient: 82.8%) patients. Within race/ethnicity groups, CRPS-1 ED visits and hospitalizations generally increased with age. Secondary findings included: 1) ED visits by Black individuals (compared with White) were significantly negatively associated with immediate hospitalization (adjusted odds ratio (AOR) 0.74, 95% CI 0.55 to 0.99); 2) hospitalizations by Black patients (compared with White) were independently associated with increased length of stay (odds ratio (OR) 1.45, 95% CI 1.07 to 1.96), though the association diminished with adjustment; and 3) drug abuse was significantly associated with hospitalization (AOR 4.67, 95% CI 3.53 to 6.18) and longer length of stay (AOR 1.81, 95% CI 1.34 to 2.46). Race/ethnicity was minimally associated with studied CRPS-1 outcomes. Additional studies are required to determine the impact of race/ethnicity on seeking care for CRPS-1.
Publicações recentes
Prediction of type 1 complex regional pain syndrome with the presence of diaschisis in hemiplegic supratentorial stroke patients.
The nonhallucinogenic ketamine metabolite (2R,6R)-hydroxynorketamine is a novel analgesic in animal models of pain.
How postmenopausal osteoporosis influences epidemiology and clinical features of CRPS-1.
Sex differences in pain-related behaviour and the endocannabinoid system following hind limb ischemia-reperfusion injury.
Bilateral Upper and Lower Limb Complex Regional Pain Syndrome (CRPS) in a Lung Cancer Survivor: Diagnostic and Interventional Challenges in the Setting of Radiculopathy and Prior Radiotherapy.
📚 EuropePMC181 artigos no totalmostrando 118
The nonhallucinogenic ketamine metabolite (2R,6R)-hydroxynorketamine is a novel analgesic in animal models of pain.
Frontiers in pain research (Lausanne, Switzerland)How postmenopausal osteoporosis influences epidemiology and clinical features of CRPS-1.
Journal of bone and mineral metabolismSex differences in pain-related behaviour and the endocannabinoid system following hind limb ischemia-reperfusion injury.
The journal of painBilateral Upper and Lower Limb Complex Regional Pain Syndrome (CRPS) in a Lung Cancer Survivor: Diagnostic and Interventional Challenges in the Setting of Radiculopathy and Prior Radiotherapy.
CureusTreatment of Chronic Achilles Tendon Ruptures by Endoscopic Flexor Hallucis Longus Transfer with Double Fixation: Results in 36 Patients at a mean follow-up of 38 Months (range, 12-58 Months).
Orthopaedics & traumatology, surgery & research : OTSRIntact endogenous pain inhibition in complex regional pain syndrome type 1.
Pain reportsMRI has limited accuracy in diagnosing complex regional pain syndrome Type 1 - a systematic review of the literature.
European journal of radiologyEvaluation of the efficacy and tolerance of pamidronate in complex regional pain syndrom type 1.
Scientific reportsBone mineral density is associated with pre-treatment pain levels of complex regional pain syndrome type 1 and predicts the response to N-containing bisphosphonates.
Clinical and experimental rheumatologyIdentification of two biological subgroups of complex regional pain syndrome type 1 by transcriptomic profiling of skin and blood in women.
Molecular medicine (Cambridge, Mass.)Effectiveness of Ultrasound-Guided Stellate Ganglion Block in Treating Pediatric Complex Regional Pain Syndrome.
CureusExamining the effects of race/ethnicity and other factors on outcomes of care for complex regional pain syndrome type 1 in the United States.
PLOS global public healthAn unresolving painful condition following a trivial peripheral fracture.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral ResearchImpact of surgeon volume on the risk of complications following volar locking plating of unstable distal radius fracture.
MedicineBenign Evolution of Complex Regional Pain Syndrome (CRPS) Type 1 in Patients Treated with Intravenous Neridronate: A Single-Center Real-Life Experience.
Pharmaceuticals (Basel, Switzerland)Outcomes of Median Nerve Release in Complex Regional Pain Syndrome Type 1 of the Hand: A Prospective Case Series.
The Journal of hand surgeryIs CRPS-1 a Chronic Disabling Disease? A Long-term, Real-Life Study on Patients Treated With Neridronate.
Clinical medicine insights. Arthritis and musculoskeletal disordersEffects of mirror therapy in post-traumatic complex regional pain syndrome type-1: a randomized controlled study.
Journal of rehabilitation medicineEfficacy of N-acetylcysteine in reducing inflammation and oxidative stress to prevent complex regional pain syndrome type 1.
MedicineEffects of Mecobalamin on the Functional Outcomes of Complex Regional Pain Syndrome Type 1 of the Foot and Ankle.
Foot & ankle internationalAdenosine triphosphate: a new player in complex regional pain syndrome type 1.
Minerva medicaExtensor Retinaculum Syndrome of the Ankle: An Adult Case Series.
Foot & ankle orthopaedicsA Case of a Father and Son With Complex Regional Pain Syndrome Type 1 Exhibiting Different Resting-State Functional Connectivity on Functional MRI.
CureusIntramuscular botulinum toxin-A in complex regional pain syndrome resistant to standard treatment: a case report.
Wiener klinische WochenschriftIncidence and Prevalence of Pain Medication Prescriptions in Pathologies with a Potential for Chronic Pain.
AnesthesiologyAn Unusual Presentation of Complex Regional Pain Syndrome Type 1.
CureusSomatotopic disruption of the functional connectivity of the primary sensorimotor cortex in complex regional pain syndrome type 1.
Human brain mappingEvidence of a genetic background predisposing to complex regional pain syndrome type 1.
Journal of medical geneticsBaseline predictors related to functional outcomes in patients older than sixty years with complex regional pain syndrome type 1 after distal radius fracture treated conservatively: a prospective observational study.
International orthopaedicsWhat Do We Know about Nociplastic Pain?
Healthcare (Basel, Switzerland)Signs and symptoms of pediatric complex regional pain syndrome - type 1: A retrospective cohort study.
Canadian journal of pain = Revue canadienne de la douleurPrediction of the Efficacy of Lumbar Sympathetic Block in Patients with Lower Extremity Complex Regional Pain Syndrome Type 1 Based on the Sympathetic Skin Response.
Pain and therapyMorphological and electrophysiological evaluation of median and ulnar nerve in complex regional pain syndrome type 1.
Pain practice : the official journal of World Institute of PainCombined use of peripheral nerve stimulation and dorsal root ganglion stimulation for refractory complex regional pain syndrome type I to avoid amputation: A case report.
Clinical case reportsModulation of mTORC1 and IL-6 following mirror therapy and pregabalin in complex regional pain syndrome type 1.
Pain managementLong-term efficacy and safety of neridronate treatment in patients with complex regional pain syndrome type 1: a pre-specified, open-label, extension study.
Therapeutic advances in musculoskeletal diseaseAcute Vision Loss Sequela of Complex Regional Pain Syndrome Type 1 Successfully Treated with Stellate Ganglion Block: Case Report.
Pain medicine case reportsEffectiveness of pulsed electromagnetic field therapy in the management of complex regional pain syndrome type 1: A randomized-controlled trial.
Turkish journal of physical medicine and rehabilitationThe Tourniquet Ischemia Test Effectively Predicts the Efficacy of Lumbar Sympathetic Block in Patients with Lower Extremity Complex Regional Pain Syndrome Type 1.
Journal of pain researchLong-term biopsychosocial issues and health-related quality of life in young adolescents and adults treated for childhood Complex Regional Pain Syndrome, type 1.
Scandinavian journal of painEffect of Perioperative Vitamin C on the Incidence of Complex Regional Pain Syndrome: A Systematic Review and Meta-Analysis.
The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle SurgeonsSuccessful treatment of complex regional pain syndrome type 1 of upper limb with cryoneurolysis of the stellate ganglion: A rare case report.
Pain practice : the official journal of World Institute of PainIntramuscular neridronate for the treatment of complex regional pain syndrome type 1: a randomized, double-blind, placebo-controlled study.
Therapeutic advances in musculoskeletal diseaseIs trigeminal neuralgia the only definitive diagnosis for pain in a tooth extraction site?
BMC oral healthInvolvement of nuclear factor κB and descending pain pathways in the anti-hyperalgesic effect of β-citronellol, a food ingredient, complexed in β-cyclodextrin in a model of complex regional pain syndrome - Type 1.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research AssociationSensory Function and Psychological Factors in Children With Complex Regional Pain Syndrome Type 1.
Journal of child neurologyAmputation With Osseointegration for Patients With Intractable Complex Regional Pain Syndrome: A Report of 3 Cases.
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Journal of chiropractic medicineDirect Sciatic Nerve Electrical Stimulation for Complex Regional Pain Syndrome Type 1.
Neuromodulation : journal of the International Neuromodulation SocietyDiagnosis of complex regional pain syndrome type 1 in patients with corticobasal degeneration: a case report.
Annals of palliative medicineType 1 Complex Regional Pain Syndrome After Subacromial Shoulder Surgery: Incidence and Risk Factor Analysis.
Indian journal of orthopaedicsDeterminants of Diagnostic Delay in Complex Regional Pain Syndrome Type 1: An Observational Study of 180 Consecutive New Cases.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseasesEffect of Early Orthopedic Rehabilitation on Development of Complex Regional Pain Syndrome Type 1.
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CureusGeneralization of exposure in vivo in Complex Regional Pain Syndrome type I.
Behaviour research and therapyThe long-term effect of complex regional pain syndrome type 1 on disability and quality of life after foot injury.
Disability and rehabilitationNociceptive mechanisms involved in the acute and chronic phases of a complex regional pain syndrome type 1 model in mice.
European journal of pharmacologyConservative Treatment for Bilateral Lower Extremity Complex Regional Pain Syndrome Type 1 after Bilateral Lung Transplant: Case Report.
PM & R : the journal of injury, function, and rehabilitationTRPV1 Channel Contributes to the Behavioral Hypersensitivity in a Rat Model of Complex Regional Pain Syndrome Type 1.
Frontiers in pharmacologyPrognostic Factors in Complex Regional Pain Syndrome Type 1 Occurring in the Korean Army.
Pain medicine (Malden, Mass.)Arthroscopic resection of wrist ganglia: About 30 cases.
Journal of orthopaedicsIncidence of and Risk Factors for Complex Regional Pain Syndrome Type 1 after Surgery for Distal Radius Fractures: A Population-based Study.
Scientific reportsPrevention of Complex Regional Pain Syndrome type 1 after conservative reatment of a distal radius fracture with a home exercise program: A proof-of-concept study.
Acta orthopaedica BelgicaEfficacy of the ketamine metabolite (2R,6R)-hydroxynorketamine in mice models of pain.
Regional anesthesia and pain medicineEffect of dexmedetomidine on the development of mechanical allodynia and central sensitization in chronic post-ischemia pain rats.
Journal of pain researchSpinal epidural abscess associated with an epidural catheter in a woman with complex regional pain syndrome and selective IgG3 deficiency: A case report.
MedicineMalingering and factitious disorder.
Practical neurologyBisphosphonates in the treatment of complex regional pain syndrome: is bone the main player at early stage of the disease?
Rheumatology internationalEpidural approach to paravertebral thoracic sympathetic block as an alternative to stellate ganglion block: A case report.
MedicineExtrapyramidal signs occurring after sympathetic block for complex regional pain syndrome responding to diphenhydramine: Two case reports.
MedicineEpithelial growth factor receptor (EGFR)-inhibition for relief of neuropathic pain-A case series.
Scandinavian journal of painSpinal cord stimulation in the treatment of complex regional pain syndrome type 1: Is trial truly required?
Clinical neurology and neurosurgeryUtilization of manual therapy to the lumbar spine in conjunction with traditional conservative care for individuals with bilateral lower extremity complex regional pain syndrome: A case series.
Physiotherapy theory and practiceComplex regional pain syndrome type 1 in the medico-legal setting: High rates of somatoform disorders, opiate use and diagnostic uncertainty.
Medicine, science, and the lawSympathetic blocks for the treatment of complex regional pain syndrome: A case series.
MedicinePain Exposure Physical Therapy versus conventional treatment in complex regional pain syndrome type 1-a cost-effectiveness analysis alongside a randomized controlled trial.
Clinical rehabilitationComplex Regional Pain Syndrome Type 1: Diagnosis and Management.
The journal of hand surgery Asian-Pacific volumeEvidence of motor system reorganization in complex regional pain syndrome type 1: A case report.
Canadian journal of pain = Revue canadienne de la douleurNeurogenic Edema from Complex Regional Pain Syndrome Resulting in Fulminant Infection Necessitating Below Elbow Amputation.
Journal of hand and microsurgeryAntiallodynic Effects of Bee Venom in an Animal Model of Complex Regional Pain Syndrome Type 1 (CRPS-I).
ToxinsTransient Osteoporosis of the Hip: A Mysterious Cause of Hip Pain in Adults.
Indian journal of orthopaedicsAntiepileptic drugs for chronic non-cancer pain in children and adolescents.
The Cochrane database of systematic reviewsAntidepressants for chronic non-cancer pain in children and adolescents.
The Cochrane database of systematic reviewsEffect of a new formulation of micronized and ultramicronized N-palmitoylethanolamine in a tibia fracture mouse model of complex regional pain syndrome.
PloS oneComplex regional pain syndrome type 1 predictors - Epidemiological perspective from a national database analysis.
Journal of clinical anesthesiaUltrasound-Guided Intra-articular Injection of the Radio-ulnar and Radio-humeral Joints and Ultrasound-Guided Dry Needling of the Affected Limb Muscles to Relieve Fixed Pronation Deformity and Myofascial Issues around the Shoulder, in a Case of Complex Regional Pain Syndrome Type 1.
Pain practice : the official journal of World Institute of PainBisphosphonates for treatment of Complex Regional Pain Syndrome type 1: A systematic literature review and meta-analysis of randomized controlled trials versus placebo.
Joint bone spineUpdate on the effects of graded motor imagery and mirror therapy on complex regional pain syndrome type 1: A systematic review.
Journal of back and musculoskeletal rehabilitationComplications after ankle and hindfoot arthroscopy.
Revista espanola de cirugia ortopedica y traumatologiaActivation of cannabinoid receptor 2 attenuates mechanical allodynia and neuroinflammatory responses in a chronic post-ischemic pain model of complex regional pain syndrome type I in rats.
The European journal of neurosciencePoster 457-B Complex Regional Pain Syndrome Type 1 in Young Male Adults.
PM & R : the journal of injury, function, and rehabilitationPulsed radiofrequency applied to the dorsal root ganglia for treatment of post-stroke complex regional pain syndrome: A case series.
Journal of clinical anesthesiaExpose or protect? A randomized controlled trial of exposure in vivo vs pain-contingent treatment as usual in patients with complex regional pain syndrome type 1.
Pain[Multidisciplinary management of children with disabling chronic pain in a French pediatric rehabilitation center: Current management and perspectives].
Archives de pediatrie : organe officiel de la Societe francaise de pediatrieComplex regional pain syndrome type 1: Analysis of 108 patients.
Reumatologia clinicaComplex Regional Pain Type 1.
Pediatric emergency careMusculoskeletal manifestations of the antiphospholipid syndrome.
LupusRecovery From Osteoporosis in a Patient With Complex Regional Pain Syndrome Type 1.
Arthritis & rheumatology (Hoboken, N.J.)Motor Imagery and Its Effect on Complex Regional Pain Syndrome: An Integrative Review.
Neurology internationalComplex Regional Pain Syndrome-Type 1 Presenting as deQuervain's Stenosing Tenosynovitis.
Pain physicianMusculoskeletal Ultrasonography in CRPS: Assessment of Muscles Before and After Motor Function Recovery with Dry Needling as the Sole Treatment.
Pain physicianAmputation as an Unusual Treatment for Therapy-Resistant Complex Regional Pain Syndrome, Type 1.
Ochsner journalEffects of Mirror Therapy in Stroke Patients With Complex Regional Pain Syndrome Type 1: A Randomized Controlled Study.
Archives of physical medicine and rehabilitationPain exposure physical therapy (PEPT) compared to conventional treatment in complex regional pain syndrome type 1: a randomised controlled trial.
BMJ openExtent of recovery in the first 12 months of complex regional pain syndrome type-1: A prospective study.
European journal of pain (London, England)Acute and chronic nociceptive phases observed in a rat hind paw ischemia/reperfusion model depend on different mechanisms.
Pflugers Archiv : European journal of physiologySkin sympathetic function in complex regional pain syndrome type 1.
Clinical autonomic research : official journal of the Clinical Autonomic Research SocietyComplex regional pain syndrome type I in children. Clinical description and quality of life.
Orthopaedics & traumatology, surgery & research : OTSRResults of Perilunate Dislocations and Perilunate Fracture Dislocations With a Minimum 15-Year Follow-Up.
The Journal of hand surgeryMusculoskeletal Ultrasonography to Distinguish Muscle Changes in Complex Regional Pain Syndrome Type 1 from Those of Neuropathic Pain: An Observational Study.
Pain practice : the official journal of World Institute of PainDo psychological factors influence recovery from complex regional pain syndrome type 1? A prospective study.
PainAre pain-related fears mediators for reducing disability and pain in patients with complex regional pain syndrome type 1? An explorative analysis on pain exposure physical therapy.
PloS oneFactors Associated With Disability and Sick Leave in Early Complex Regional Pain Syndrome Type-1.
The Clinical journal of painBilateral complex regional pain syndrome in a woman with major depressive disorder.
Archives of Iranian medicinePotential risk factors for the onset of complex regional pain syndrome type 1: a systematic literature review.
Anesthesiology research and practice[Complex regional pain syndrome type 1: negating the myth].
Nederlands tijdschrift voor geneeskunde[Complex regional pain syndrome type 1 after fracture of distal phalanx: case report].
Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of AlgologyAssociações
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- The nonhallucinogenic ketamine metabolite (2R,6R)-hydroxynorketamine is a novel analgesic in animal models of pain.
- How postmenopausal osteoporosis influences epidemiology and clinical features of CRPS-1.
- Sex differences in pain-related behaviour and the endocannabinoid system following hind limb ischemia-reperfusion injury.
- MRI has limited accuracy in diagnosing complex regional pain syndrome Type 1 - a systematic review of the literature.
- Examining the effects of race/ethnicity and other factors on outcomes of care for complex regional pain syndrome type 1 in the United States.
- Prediction of type 1 complex regional pain syndrome with the presence of diaschisis in hemiplegic supratentorial stroke patients.
- Bilateral Upper and Lower Limb Complex Regional Pain Syndrome (CRPS) in a Lung Cancer Survivor: Diagnostic and Interventional Challenges in the Setting of Radiculopathy and Prior Radiotherapy.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:99995(Orphanet)
- MONDO:0011441(MONDO)
- GARD:16928(GARD (NIH))
- Busca completa no PubMed(PubMed)
- Artigo Wikipedia(Wikipedia)
- Q3961690(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
