Coriorretinopatia serosa central

the Study of the Association Between the Gut Microbiota and Central Serous Chorioretinopathy

NCT06527326

Central Serous Chorioretinopathy and Micropulse Laser Treatment

NCT06346405

Biomarkers and Choroidal Neovascularization

NCT04439708

OCT in Rare Chorioretinal Diseases

NCT02141308

Faricimab for Chronic Central Serous Chorioretinopathy: A Randomized Sham-Controlled Trial

NCT07681167

EM ANDAMENTO

Onde estão os ensaios

Com ensaio aberto em 13 países. O ponto verde marca onde há vaga agora.

🟢 Recrutando agora

4 pesquisas recrutando participantes. Converse com seu médico sobre a possibilidade de participar.

NCT06527326 · the Study of the Association Between the Gut Microbiota and …Recrutando

NCT06346405 · Central Serous Chorioretinopathy and Micropulse Laser Treatm…Recrutando

🇮🇹 Itália

NCT04439708 · Biomarkers and Choroidal NeovascularizationRecrutando

🇫🇷 França

NCT02141308 · OCT in Rare Chorioretinal DiseasesRecrutando

NCT07681167 · Faricimab for Chronic Central Serous Chorioretinopathy: A Ra…Em breve

Outros ensaios clínicos

81 ensaios clínicos encontrados, 9 ativos.

Distribuição por fase

PHASE2

NCT07767058 · Mindfulness for Central Serous ChorioretinopathyEm breve

NA🇬🇧 Reino Unido

NCT07298174 · Wide Field OCTA in Ocular DiseasesEm breve

NCT07347119 · Prospective Geometric Analysis of Ultra-Widefield OCTA Chara…Em breve

🇨🇳 China

NCT06809751 · Evaluating Efficacy and Safety of Oral Melatonin in Acute Ce…Em breve

PHASE2, PHASE3

NCT01327170 · Micropulse Diode Laser Treatment for Chronic Central Serous …Concluído

NA🇧🇷 Brasil

NCT05847049 · Eplerenone, Aflibercept and Topical Nepafenac Serous Foveal …Concluído

🇪🇬 Egito

NCT04723160 · Computer Aided Diagnosis of Multiple Eye Fundus Diseases Fro…Concluído

🇨🇳 China

NCT04224831 · Treatment of Chronic Central Serous Chorioretinopathy Via El…Concluído

NATurkey (Türkiye)

NCT03497000 · Effects of OCTA-guided PDT in Acute CSCConcluído

NCT03339856 · Selective Retina Therapy With Real-Time Feedback-Controlled …Concluído

NCT02587767 · 577nm Micropulse Laser vs Half-dose Photodynamic Therapy on …Concluído

NCT03950089 · Optical Coherence Tomography Angiography (OCT-A) and Central…Concluído

NCT02784665 · Treatment Trial for Acute Central Serous ChorioretinopathyConcluído

NCT03758963 · Selective Retina Therapy With 'R:GEN' in Patients With Centr…Concluído

NASouth Korea

NCT02735213 · Micropulse 577nm Laser vs Traditional Laser Treatment in Cen…Concluído

PHASE2, PHASE3🇨🇳 China

NCT05104138 · Eplerenone Versus PDT: Comparative Study by OCTAConcluído

NCT02354170 · Short-Term Oral Mifepristone for Central Serous Chorioretino…Concluído

NCT04356716 · Sildenafil for Treatment of Choroidal IschemiaConcluído

NCT02462499 · Eplerenone Treatment for Chronic Central Serous Chorioretino…Concluído

PHASE4Hungary

NCT01797861 · Prospective Randomized Controlled Treatment Trial for Chroni…Concluído

PHASE4🇫🇷 França · 🇩🇪 Alemanha · 🇳🇱 Países Baixos +1

NCT01971190 · Efficacy and Safety of Intravitreal Aflibercept Injection fo…Concluído

PHASE2South Korea

NCT01990677 · Eplerenone for the Treatment of Central Serous Chorioretinop…Concluído

NA🇺🇸 Estados Unidos

NCT01822561 · Eplerenone for Central Serous ChorioretinopathyConcluído

NCT02036632 · Eye Patch Therapy for Central Serous Retinopathy (CSR)Concluído

PHASE1🇺🇸 Estados Unidos

NCT01880788 · Genetic Analysis of Chronic Central Serous Chorioretinopathy…Concluído

NCT01710332 · The Safety & Efficacy of Intravitreal Aflibercept Injection …Concluído

NCT01692938 · Evaluation of the Precision of the Microperimetry Function o…Concluído

NCT01468337 · Topical Interferon Gamma-1b for Central Serous Chorioretinop…Concluído

NCT01378130 · Central Serous Chorioretinopathy: Etiology, Course and Progn…Concluído

🇦🇹 Áustria

NCT01574430 · Study of Photodynamic Therapy (PDT) in Patients With Central…Concluído

PHASE4🇨🇳 China

NCT01227993 · Extension Study for the Evaluation of Finasteride in the Tre…Concluído

NCT01325181 · Ranibizumab Versus Low-fluence Photodynamic Therapy in the T…Concluído

PHASE1, PHASE2South Korea

NCT00837252 · Pilot Study for the Evaluation of Finasteride in the Treatme…Concluído

NCT01019668 · Central Serous Chorioretinopathy Treated by Modified Photody…Concluído

NA🇹🇼 Taiwan

NCT01434095 · Microperimetric Evaluation After Half-dose Photodynamic Ther…Concluído

NA🇯🇵 Japão

NCT00817245 · Effect of Helicobacter Pylori Treatment on Idiopathic Centra…Concluído

PHASE1, PHASE2Iran

NCT00803517 · Comparison of Multifocal Electroretinogram Assessment in Chr…Concluído

South Korea

NCT00802906 · Bevacizumab Versus Micropulse in Central Serous Chorioretino…Concluído

NA🇩🇪 Alemanha

NCT00489840 · Treatment of Chronic Central Serous Chorioretinopathy With O…Concluído

NCT00987077 · Selective Retina Therapy (SRT) in Patients With Idiopathic C…Concluído

PHASE2🇩🇪 Alemanha

NCT00403325 · Intravitreal Ranibizumab Treatment of Central Serous Chorior…Concluído

PHASE1🇺🇸 Estados Unidos

NCT00211393 · A Pilot Study of the Treatment of Central Serous Chorioretin…Concluído

NCT00963131 · High-dose Antioxidants for Central Serous ChorioretinopathyConcluído

PHASE2Thailand

NCT00211445 · Photodynamic Therapy Using Verteporfin for Treatment of Chro…Concluído

NCT00005784 · Evaluation and Treatment of Patients With Retinal DiseaseConcluído

NCT06468540 · Combination of Micropulse Laser With or Without Photodynamic…UNKNOWN

NCT05633576 · Steroid Eye Drops in Chronic Central Serous Chorioretinopath…UNKNOWN

PHASE3🇳🇱 Países Baixos

NCT05687422 · Two Patterns of Micropulse Laser in the Treatment of Chronic…UNKNOWN

NCT05570591 · Subthreshold Nanosecond Laser for Non-resolving Central Sero…UNKNOWN

NA🇦🇺 Austrália

NCT05589974 · Choroidal Blood Flow in Acute and Chronic Central Serous Cho…UNKNOWN

🇳🇴 Noruega

NCT05337332 · Results of Suprachoroidal Steroids Injections in Two Chorior…UNKNOWN

PHASE2, PHASE3🇪🇬 Egito

NCT05278169 · Central Serous Chorioretinopathy Registry and Pachychoroid O…UNKNOWN

Hong Kong

NCT04936490 · Crocin Supplementation in CSCRUNKNOWN

PHASE1Iran

NCT04665102 · Pilot Study on Deep Learning in the EyeUNKNOWN

NCT04410861 · Panmacular Versus Minimal Micropulse Laser Therapy in Centra…UNKNOWN

NAUnited Arab Emirates

NCT05390619 · Different Doses of vPDT in the Treatment of cCSCUNKNOWN

NCT02681783 · PRedictive Factors and Changes From Treatment in iPCV Versus…UNKNOWN

PHASE4🇨🇦 Canadá

NCT03542006 · Brinzolamide for the Treatment of Chronic Central Serous Cho…UNKNOWN

PHASE2🇦🇷 Argentina · 🇮🇱 Israel

NCT03079141 · Photodynamic Therapy Versus Eplerenone: Treatment Trial for …UNKNOWN

PHASE4🇳🇱 Países Baixos

NCT03692169 · The Changes of Retinal Capillaries After Half-dose PDT Measu…UNKNOWN

🇨🇳 China

NCT02815176 · Angiographic Characteristics of CSC, PCV Patients and Thromb…UNKNOWN

South Korea

NCT02799992 · Pseudo-PDT in Central Serous ChorioretinopathyUNKNOWN

NCT02215330 · A Study of the Beneficial Effects of Eplerenone on Central S…UNKNOWN

PHASE2, PHASE3🇦🇹 Áustria

NCT02153125 · Eplerenone For the Treatment of Chronic Central Serous Chori…UNKNOWN

PHASE2🇮🇱 Israel

NCT01633983 · Methotrexate for Central Serous Chorioretinopathy Treatment …UNKNOWN

PHASE2🇮🇱 Israel

NCT01630863 · The Safe Effective Light Dose of Photodynamic Therapy for Ch…UNKNOWN

NASouth Korea

NCT00864773 · The Effect of Therapy With Bevacizumab in Chronic Central Se…UNKNOWN

NCT00403884 · Selective RPE Laser Treatment (SRT) for Various Macular Dise…UNKNOWN

NA🇩🇪 Alemanha

NCT05686421 · Comfortable and Stabilizing Chin & Forehead Rest Attachment …Encerrado

NA🇺🇸 Estados Unidos

NCT02889185 · Multimodal Imaging in Central Serous ChorioretinopathyEncerrado

NA🇫🇷 França

NCT01982383 · Study on the Use of Micropulse Laser to Treat Central Serous…Encerrado

NA🇺🇸 Estados Unidos

NCT01585441 · Finasteride for Chronic Central Serous ChorioretinopathyEncerrado

NCT02088151 · Selective Retinal Pigment Epithelium Laser Therapy for Macul…Encerrado

NA🇨🇭 Suíça

NCT05679180 · Navigated Microsecond Laser for Chronic Central Serous Chori…Cancelado

NCT01256580 · Intravitreal Bevacizumab vs.Combination Therapy for CNV Due …Cancelado

NCT00418431 · Intravitreal Bevacizumab for the Treatment of Central Serous…Cancelado

PHASE2, PHASE3🇲🇽 México

Ver todos no ClinicalTrials.gov

🧪 Está conduzindo uma pesquisa?

Divulgue para pacientes e familiares que acompanham esta doença.

Divulgar pesquisa →

Publicações mais relevantes

📖Melhor nível de evidência: Revisão

Timeline de publicações

2.291 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 2.291

#1

Combined Therapy Versus Fortified Anti-VEGF Monotherapy in Type C Polypoidal Choroidal Vasculopathy: Long-Term Outcomes and Exploratory Biomarker Insights.

International journal of molecular sciences2026 Jan 26

While standard anti- vascular endothelial growth factor (VEGF) therapy, with or without photodynamic therapy (PDT), is effective for patients with polypoidal choroidal vasculopathy (PCV), not all achieve optimal visual outcomes. This study aimed to compare fortified (double the dose and the volume of the standard one) anti-VEGF combined with PDT versus fortified anti-VEGF monotherapy and to investigate biomolecular profiles and disease relationships among PCV, neovascular age-related macular degeneration (nvAMD), and central serous chorioretinopathy (CSCR). The goal was to identify novel pathways to inform future therapeutic strategies, including hypoxia-inducible factors (HIF)-1α inhibitors. This retrospective cohort study included 23 eyes with indocyanine green-confirmed type C PCV. One eye treated with transpupillary thermotherapy was not included in the following two groups. Patients received either combined therapy (PDT + fortified-dose anti-VEGF; n = 12) or fortified-dose anti-VEGF monotherapy (n = 10). Primary outcomes were changes in best-corrected visual acuity (BCVA) and central retinal thickness (CRT). Secondary outcomes included injection burden and recurrence. Exploratory analyses examined aqueous biomarkers, including VEGF, placental growth factor (PlGF), β-catenin, HIF-1α, and Wnt1 across PCV, CSCR, and nvAMD to identify novel therapeutic targets. Significant (p = 0.003/p = 0.005) median CRT reduction was similar (p = 0.468) between groups (combined/monotherapy: 137.5 µm/106.5 µm). BCVA (median [Q1, Q3]) change in logarithm of the minimum angle of resolution (LogMAR) was not statistically significant (p = 0.279), with 0.25 [0.00, 0.98] in the combined group versus 0.00 [-0.03, 0.28] in the monotherapy group. Treatment burden of anti-VEGFs per person per year was lower with combined therapy (1.16 ± 0.47# PDT + 2.81 ± 0.92# anti-VEGF injections) compared with monotherapy (4.61 ± 1.49# injections). Six eyes demonstrated recurrence at a mean of 15.5 months. Incomplete regression of polyps and branching vascular networks was observed in all eyes. Exploratory biomarker analysis revealed significantly (p < 0.05) higher VEGF and PlGF levels in nvAMD compared with PCV. nvAMD also demonstrated significantly (p < 0.05) higher β-catenin and lower HIF-1α levels relative to PCV and CSCR, while no significant biomarker differences were observed between PCV and CSCR. Combined therapy or monotherapy with fortified anti-VEGFs reduced treatment burden and achieved significant anatomical improvement but did not yield superior functional outcomes, highlighting the therapeutic difficulty of type C PCV. Biomarker profiling revealed shared hypoxia-related mechanisms between PCV and CSCR, with elevated HIF-1α compared to nvAMD indicating a "preliminary" possible role for HIF-1α inhibitors. Differential expression of these biomarkers highlights additional molecular pathways that may inform future targeted interventions.

#2

Correction: Effect of photodynamic therapy on choroid of the medial area from optic disc in patients with central serous chorioretinopathy.

PloS one2026

[This corrects the article DOI: 10.1371/journal.pone.0282057.].

#3

The CFH-CFHR5 Locus in Wet Age-Related Macular Degeneration, Polypoidal Choroidal Vasculopathy, and Central Serous Chorioretinopathy.

Ophthalmology science2026 Feb

To evaluate the effects of haplotype-tagging single nucleotide polymorphisms (SNPs) in the complement factor H-complement factor H related 5 (CFH-CFHR5) locus on neovascular age-related macular degeneration (nAMD), polypoidal choroidal vasculopathy (PCV), and chronic central serous chorioretinopathy (cCSCR) in Chinese patients. Case-control genetic association study. A total of 846 patients (341 nAMD, 288 PCV, and 217 cCSCR including 43 with secondary macular neovascularization [MNV]) and 632 healthy Chinese controls. A total of 17 candidate SNPs were initially selected from the CFH-CFHR5 region; after excluding 5 SNPs that deviated from Hardy-Weinberg equilibrium, 12 SNPs were retained for the final analysis. Association analyses included logistic regression adjusted for age and sex and haplotype-based analysis using Haploview. Study-wide significance threshold was set at P < 0.0042 for allelic tests (Bonferroni-corrected for 12 SNPs) and at P < 0.05 for haplotype tests (adjusted using 10 000 permutations). Associations between individual SNPs and haplotypes in the CFH-CFHR5 locus with nAMD, PCV, and cCSCR (with or without MNV), respectively. The tagging SNP, rs12144939, for the CFHR3/1 deletion was significantly associated with nAMD (odds ratio [OR] = 0.37, P = 0.0031). Notably, we identified 3 candidate variants showing novel associations with PCV, including rs12144939 (OR = 0.29, P = 6.29 × 10-4), rs423641 in CFHR1 (OR = 0.74, P = 0.0038), and rs10922152 in CFHR5 (OR = 1.55, P = 0.0031). No SNP in this locus was associated with cCSCR without MNV, whereas CFH rs529825 was nominally associated with cCSCR with MNV (OR = 0.47, P = 0.0047). Similar patterns of haplotype associations were observed across the 3 maculopathies. Notably, the haplotype A-T-C-G spanning CFHR4, CFHR2, and CFHR5 (OR = 1.81, permutation P = 0.0099) and haplotype G-A-G within CFHR5 (OR = 1.56, permutation P = 0.025) were specifically associated with PCV. This study validates the association of the CFHR3/1 deletion (tagged by rs12144939) with nAMD. Furthermore, we reveal a novel genetic architecture for PCV within the CFH-CFHR5 locus, characterized by associations at rs12144939, rs423641 (CFHR1), and rs10922152 (CFHR5), as well as risk haplotypes unique to PCV. These findings underscore the critical role of CFH-related genes in PCV and provide new insights into its genetic mechanisms. The author has no/the authors have no proprietary or commercial interest in any materials discussed in this article.

#4

Selective Retina Therapy With Fundus Image-Based Titration in Central Serous Chorioretinopathy: Prospective Outcomes and Predictive Factors.

Translational vision science & technology2026 Jan 05

We evaluated the clinical outcomes of selective retina therapy (SRT) with fundus image-based titration approach for central serous chorioretinopathy (CSC). Sixty eyes (60 participants) with chronic CSC prospectively underwent SRT. Treatment (527-nm wavelength, 1.7-µs pulse duration) targeted leakage sites identified via fundus fluorescein angiography. Pulse energy and micropulse number were adjusted based on test-spot fundus images. Changes in best-corrected visual acuity (BCVA), central foveal thickness, subfoveal choroidal thickness, and subretinal fluid (SRF) height were evaluated at baseline and at 1, 2, and 3 months post treatment. Retinal sensitivity was measured by microperimetry at baseline and 3 months. Outcomes were compared between eyes with completely resolved or residual SRF at 3 months. At 3 months, complete SRF resolution was observed in 80.8% of eyes (42/52). The mean SRF height decreased from 135.6 ± 81.9 µm to 28.0 ± 72.0 µm, and the mean central foveal thickness from 318.9 ± 88.0 µm to 231.9 ± 69.8 µm (both P < 0.001). In parallel, functional parameters also improved, with mean best-corrected visual acuity increasing from 0.17 ± 0.15 logarithm of the minimum angle of resolution to 0.06 ± 0.12 logarithm of the minimum angle of resolution and mean deviation of retinal sensitivity from -0.89 ± 1.65 dB to 0.02 ± 1.29 dB (both P < 0.001). Female sex was significantly associated with persistent SRF in both univariate and multivariable analyses (odds ratio, 30.794; 95% confidence interval, 2.996-774.668; P = 0.011). SRT with fundus image-based titration yielded favorable functional and anatomical outcomes in CSC. Female sex was associated with persistent SRF, although this finding should be interpreted cautiously. Fundus image-based titration translates selective retinal pigment epithelium targeting in selective retina therapy into a reproducible clinical approach for central serous chorioretinopathy. This strategy facilitates individualized treatment while remaining compatible with routine clinical practice.

#5

Neurosymbolic AI Framework for Explainable Retinal Disease Classification From OCT Images.

Translational vision science & technology2026 Jan 05

Accurate classification of retinal diseases such as dry age-related macular degeneration, wet AMD, epiretinal membrane, full-thickness macular hole (MH), lamellar MH, and central serous chorioretinopathy (CSC) is essential for effective treatment and clinical decision-making. Traditional deep learning models, however, often struggle with imbalanced datasets and lack interpretability, limiting their translational applicability in ophthalmology. We propose a neurosymbolic framework that integrates a convolutional neural network (CNN) with a symbolic reasoning layer based on expert-defined clinical rules. A total of 10,846 optical coherence tomography images were retrospectively collected and categorized into seven diagnostic classes: dry AMD, wet AMD, epiretinal membrane, full-thickness MH, lamellar MH, central serous chorioretinopathy, and healthy retinas. Our neurosymbolic model achieved macro-precision 0.83, recall 0.82, and F1 0.81, on internal dataset, having slightly better performance than the CNN (0.64/0.83/0.68). On the external dataset, it retained superior performance, macro-precision 0.85, recall 0.79, F1 0.78, versus the CNN (0.73/0.64/0.59). Our hybrid neurosymbolic framework introduces a unified paradigm that couples symbolic reasoning with a conventional CNN, improving diagnostic performance while delivering transparent, clinically interpretable decisions. It is particularly effective for rare and complex conditions that often challenge end-to-end deep learning models. By integrating symbolic clinical logic with visual pattern recognition, the neurosymbolic model fosters trust in artificial intelligence-assisted diagnostics and supports precise, explainable decision-making in retinal care.

Publicações recentes

Treatment of Central Serous Chorioretinopathy With Topical Difluprednate: A Literature Review.

🥉 Relato de caso

Cureus2026 Mar

Migraine as a risk factor for retinal vascular events and maculopathies: a systematic review and meta-analysis of 47 million individuals.

J Headache Pain2026 Apr 15

Non-Neoplastic Uveitis Masquerade Syndromes: Insights from a Case Series.

Ocul Immunol Inflamm2026 Apr 13

Correlation of CS and OCTA biomarkers in CSCR.

📖 Revisão

Rom J Ophthalmol2025 Oct-Dec

Central Serous Chorioretinopathy Following Corticosteroid Injection for Thumb Carpometacarpal Osteoarthritis: A Case Report.

🥉 Relato de caso

J Orthop Case Rep2026 Apr

Ver todas no PubMed

📚 EuropePMC2.623 artigos no totalmostrando 196

CLINICAL AND IMAGING PREDICTORS OF BILATERAL INVOLVEMENT IN CENTRAL SEROUS CHORIORETINOPATHY.

Clinical & experimental optometry

Anterior uveal morphometrics in complex central serous chorioretinopathy: insights from ultrasound biomicroscopy and anterior segment optical coherence tomography.

Prognostic value of foveal choroidal vascular hyperpermeability on indocyanine green angiography in central serous chorioretinopathy.

Assessment of artifact-removed choriocapillaris flow voids in eyes with pachychoroid spectrum disorders.

Ultra-widefield indocyanine green angiography findings of vortex veins in central serous chorioretinopathy.

Long-term follow-up of PLACE and SPECTRA trials: outcomes after successful and unsuccessful half-dose photodynamic therapy for chronic central serous chorioretinopathy.

Photodynamic therapy and anti-vascular endothelial growth factor for acute central serous chorioretinopathy: An updated systematic review and meta-analysis.

Association Between Pseudoexfoliation Glaucoma and Central Serous Chorioretinopathy.

Ophthalmic surgery, lasers & imaging retina

Inner Collagenous Layer Detachment: A Novel Optical Coherence Tomography Sign in Avascular Serous Pigment Epithelial Detachment Secondary to Central Serous Chorioretinopathy.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Hormonal factors in the pathophysiology of central serous chorioretinopathy - a systematic review and meta-analysis.

European journal of ophthalmology

Evaluation of static and dynamic pupillometry parameters in patients with central serous chorioretinopathy.

Central Serous Chorioretinopathy is Associated with Increased Cardiovascular Risk: An Artificial Intelligence-Based Retinal Analysis.

Ophthalmic epidemiology

Archivos de la Sociedad Espanola de Oftalmologia

Childhood central serous chorioretinopathy: An uncommon cause of neurosensory macular detachment.

Central Serous Chorioretinopathy in Parallel With Onset and Relapses of Minimal Change Nephrotic Syndrome: A 28-Year Case Follow-Up.

A bibliometric and visualized analysis of choriocapillaris from 2013 to 2023.

An intelligent segmentation method for leakage points in central serous chorioretinopathy based on fluorescein angiography images.

Demography, Clinical Characteristics and Long-Term Outcomes of Central Serous Chorioretinopathy in Women. MICRoN Report Number Fourteen.

Clinical Characteristics and Outcomes in Central Serous Chorioretinopathy with Subretinal Hyper-Reflective Material: MICRoN report 6.

Update on subthreshold micropulse laser treatment for retinal diseases: A narrative review.

Chronic Central Serous Chorioretinopathy with and without Myopia: Clinical Features and Response to Half-Dose Photodynamic Therapy.

Eplerenone for Central Serous Chorioretinopathy: Is There Still Room for This Treatment?

Biomedicines

Dermatology online journal

Corticosteroid-induced central serous chorioretinopathy in a pemphigus vulgaris patient.

Outer Retinal Erosion and Outer Retinal Pinching at the Origin of Subretinal Fluid in Central Serous Chorioretinopathy.

The Amsler Grid in Everyday Practice: A Review of Its Role and Limitations in Primary Care.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Choroidal imaging biomarkers as predictors of recurrent central serous chorioretinopathy: A multicenter retrospective study - MICRoN report number five.

Secondary Multiple Evanescent White Dot Syndrome Associated with Active Central Serous Chorioretinopathy.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Choriocapillaris flow deficits and choroidal vascular index in the fellow eye of patients with central serous chorioretinopathy.

International journal of molecular sciences

Combined Therapy Versus Fortified Anti-VEGF Monotherapy in Type C Polypoidal Choroidal Vasculopathy: Long-Term Outcomes and Exploratory Biomarker Insights.

The Role of Nailfold Videocapillaroscopy (NVC) in Evaluating Ocular Diseases: Insights into Retinal, Choroidal, and Optic Nerve Pathologies.

Risk factors for the development of subretinal fluid in the fellow eyes of patients with chronic central serous chorioretinopathy.

American journal of ophthalmology case reports

Increased peripapillary choroidal blood flow velocity in peripapillary pachychoroid syndrome: Three case reports with referential observations in central serous chorioretinopathy.

Deutsches Arzteblatt international

Central Serous Chorioretinopathy: Etiology, Diagnosis, and Treatment.

Long-term follow-up of chronic central serous chorioretinopathy patients receiving oral eplerenone and half-dose photodynamic therapy in the SPECTRA trial: SPECTRA trial report No. 4.

Association between central serous chorioretinopathy and personality types: A systematic review and meta-analysis.

Klinische Monatsblatter fur Augenheilkunde

Efficacy of Photodynamic Therapy in Chronic Central Serous Chorioretinopathy: A Retrospective Analysis at Hanusch Hospital, Vienna.

Prevalence and associations of central serous chorioretinopathy in a population aged 50+ years. The Beijing Eye Study.

Large-caliber choroidal arteriovenous shunt in macular neovascularization: A brief report of a novel morphological finding.

Hyperreflective choroidal foci may predict pachychoroid macular atrophy development in central serous chorioretinopathy.

Dichotomous pathogenesis drives therapeutic choice: A case report and review of literature differentiating glucocorticoid-induced from disease activity-associated central serous chorioretinopathy in lupus nephritis.

Lupus

Journal of proteome research

Proteomic Signature in Men with Central Serous Chorioretinopathy.

Journal of vitreoretinal diseases

Venous Overload Choroidopathy With Coexisting Chronic Central Serous Chorioretinopathy and Uveal Effusion Syndrome.

The CFH-CFHR5 Locus in Wet Age-Related Macular Degeneration, Polypoidal Choroidal Vasculopathy, and Central Serous Chorioretinopathy.

Peripapillary intervortex venous anastomoses in central serous chorioretinopathy.

Beyond the vision: central serous chorioretinopathy, anxiety and depression-a systematic review.

Frontiers in medicine

Dim Flicker: An Endogenous Visual Percept and Its Disease Associations.

Vitreoretinal disease detection using artificial intelligence: a systematic review and meta-analysis.

Ophthalmic surgery, lasers & imaging retina

Bilateral Central Serous Chorioretinopathy in a Patient With XYY Syndrome.

Off-label intravitreal brolucizumab and bevacizumab for chronic central serous chorioretinopathy.

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde

Elevated Anxiety Levels in Central Serous Chorioretinopathy: Evidence from a Prospective Case-Control Study.

Selective Retina Therapy With Fundus Image-Based Titration in Central Serous Chorioretinopathy: Prospective Outcomes and Predictive Factors.

Neurosymbolic AI Framework for Explainable Retinal Disease Classification From OCT Images.

Exploring retinal and choroidal characteristics on multimodal imaging in resolved central serous chorioretinopathy.

Punctate Hyperfluorescent Spots on Indocyanine Green Angiography in Eyes with Central Serous Chorioretinopathy and Patient Demographics.

A Novel Panmacular Strategy for Subthreshold Micropulse Laser in CSC: Two-Year Functional and Morphological Outcomes.

Long-term outcomes of titration-guided focal selective retina therapy for chronic central serous chorioretinopathy: retrospective real-world data analysis.

BMC ophthalmology

Optical density ratio as a prognostic biomarker for chronicity in Central Serous Chorioretinopathy.

The "scolex" sign" - A distinct hyperreflective foci on the wall of serous pigment epithelial detachments in central serous chorioretinopathy - MICRON Report Number Seven.

Evaluation of Changes in Optical Coherence Tomography (OCT) Biomarkers After Oral Eplerenone Therapy in Chronic Central Serous Chorioretinopathy and Their Correlation to Functional Visual Outcome.

Pilot Study of Choroidal Synphlebia.

Imaging characteristics of macular neovascularization in chronic central serous chorioretinopathy patients.

A deeper assessment of various choroidal and demographic biomarkers among symptomatic pachychoroid spectrum entities within a tertiary referral center.

A deep learning-based pachychoroid index based on choroidal image patterns of central serous chorioretinopathy using enhanced-depth-imaging optical coherence tomography.

Bilateral Central Serous Chorioretinopathy Associated With Tuberculosis in a Female Patient.

REDUCTION OF SCLERAL THICKNESS WITH TOPICAL FLUOROMETHOLONE IN MANAGEMENT OF CHRONIC CENTRAL SEROUS CHORIORETINOPATHY COMPLICATED BY POSTERIOR CYSTOID DEGENERATION.

Severe bilateral chorioretinopathy associated with ipilimumab in a patient with metastatic melanoma.

GMS ophthalmology cases

EXOGENOUS TESTOSTERONE USE AND ACUTE CENTRAL SEROUS CHORIORETINOPATHY IN A TRANSGENDER PATIENT.

Oral Eplerenone for Exudative Retinal Detachment Secondary to Central Serous Chorioretinopathy: A Case Report.

A Randomized-Controlled Trial of the Efficacy, Safety and Tolerability of Intravitreal Brolucizumab in Patients With Chronic Central Serous Chorioretinopathy With Persistent Fluid in the Absence of Choroidal Neovascular Membrane-BRICS Trial Report II.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

The spectrum of pachychoroid neovasculopathy.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Pachychoroid pigment epitheliopathy and macular venous outflow abnormalities: the effects of venous stasis.

Selective and nonselective mineralocorticoid receptor antagonists in central serous chorioretinopathy: systematic review and meta-analysis.

BMC ophthalmology

International journal of molecular sciences

Systemic Lupus Erythematosus: Ophthalmological Safety Considerations of Emerging and Conventional Therapeutic Agents.

Multimodal imaging predictors of recurrence after photodynamic therapy in chronic central serous chorioretinopathy.

Full-Spectrum Pachychoroid Manifestation in One Eye: A Case Report.

A coarse-to-fine registration method for multimodal retinal images.

Seasonal variation in the incidence of central serous chorioretinopathy: A systematic review and meta-analysis.

International journal of retina and vitreous

Choroidal neovascularization as a trigger for central serous chorioretinopathy.

Systemic C-reactive protein levels and central serous chorioretinopathy: A systematic review with meta-analysis.

Short-Term Topical Minoxidil Use Associated with Acute Central Serous Chorioretinopathy: A Case Report.

When Erectile Dysfunction Therapy Clouds the Vision: ST-BRVO after Sildenafil in a Healthy Male.

Subretinal Fluid Duration and Clinical Outcomes in Central Serous Chorioretinopathy: An Analysis of Time-to-Photodynamic Therapy.

Journal of vitreoretinal diseases

Exogenous Hormone Use as a Predictor of Central Serous Chorioretinopathy Recurrence: A Comparative Analysis of Observation Versus Low-Fluence Photodynamic Therapy.

International journal of retina and vitreous

Selective retina therapy for central serous chorioretinopathy with focal choroidal excavation: a retrospective case series of six eyes.

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde

Clinical Features and Outcomes of Bullous Central Serous Chorioretinopathy: A Multicentric Cohort Study.

Journal of ophthalmic & vision research

Hyperreflective Choroidal Foci: A Comprehensive Review.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Three-dimensional choroidal vessels assessment in central serous chorioretinopathy.

Transplantation proceedings

Evaluation of Long-Term Ocular Findings in Liver Transplant Patients: Comparison of Pediatric and Adult Age Groups.

Three-Dimensional Choroidal Contour Mapping in Central Serous Chorioretinopathy and Fellow Eyes.

Visual Disturbance During Pregnancy: A Case Report of Central Serous Chorioretinopathy.

The urinary 6-sulfatoxymelatonin level in patients with central serous chorioretinopathy and its correlation with choroidal vasculature.

A comparative study of choroidal thickness and pigment epithelial detachment in acute and chronic central serous chorioretinopathy in Nepalese patients.

PloS one

Novel Finding of Retinal Aneurysmal Alterations in Patients Undergoing Fingolimod Therapy for Multiple Sclerosis.

Neurology and therapy

Half-time photodynamic therapy for serous pigment epithelium detachment: anatomical and functional outcomes.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Efficacy and safety of intravitreal faricimab for choroidal neovascularization secondary to central serous chorioretinopathy - a multicentre study.

Photobiomodulation Therapy with Low-Level Light in Chronic Central Serous Chorioretinopathy: A Pilot Study.

Expert review of medical devices

Advances in minimally traumatic retinal laser therapy.

Pentraxin-3 and Lipocalin-2 are decreased in patients with uveal effusion syndrome.

Association of Migraine With Increased Risk of Central Serous Chorioretinopathy: A Retrospective Cohort Study.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Volumetric choroidal biomarkers in central serous chorioretinopathy using swept-source optical coherence tomography: a deep learning approach.

Retinal fingerprint pattern in central serous chorioretinopathy.

DIAGNOSTIC PERFORMANCE OF MACHINE LEARNING TECHNOLOGY USING OPTICAL COHERENCE TOMOGRAPHIC IMAGE IN RETINAL DISEASES PRESENTED WITH SUBRETINAL FLUID.

Corneal Nerve Abnormalities in Chronic Central Serous Chorioretinopathy.

European journal of ophthalmology

Embossing enhances visualization of retinal pigment epithelium alterations in fundus autofluorescence in central serous chorioretinopathy.

Efficacy and Safety of Intravitreal Brolucizumab in Chronic Central Serous Chorioretinopathy: A Retrospective Cohort Study [Response to Letter].

Efficacy and Safety of Intravitreal Brolucizumab in Chronic Central Serous Chorioretinopathy: A Retrospective Cohort Study [Letter].

Changes in choriocapillaris blood flow following half-fluence, full-dose photodynamic therapy (PDT) and half-fluence, half-dose PDT in patients with central serous chorioretinopathy: A quantitative analysis of early post-treatment alterations.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)

International consensuses and guidelines on central serous chorioretinopathy (CSC) by the Asia Pacific Vitreo-retina Society (APVRS), the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) and the Academia Retina Internationalis (ARI).

Ocular immunology and inflammation

Non-Neoplastic Disorders Mimicking Posterior Segment Inflammation.

Evaluation of Leak Sites in Central Serous Chorioretinopathy and the Effects of PDT on RPE by Polarization-Sensitive OCT.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Predictors of persistent central serous chorioretinopathy: a multicenter retrospective study - MICRoN report number four.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Evaluation of choriocapillaris perfusion changes in chronic central serous chorioretinopathy following Half-Dose photodynamic therapy.

Bilateral Choroidal Metastases Mimicking Central Serous Chorioretinopathy: A Diagnostic Challenge.

Ocular oncology and pathology

Secondary Choroidal Osteoma in the Setting of Uveal Pathology: 4 Case Reports and Review.

THE ROLE OF EN FACE IMAGING OF RETINAL PIGMENT EPITHELIUM ALTERATIONS IN RAPID CLASSIFICATION OF CENTRAL SEROUS CHORIORETINOPATHY USING WIDEFIELD SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY.

A comprehensive overview: deep learning approaches to central serous chorioretinopathy diagnosis.

BMC ophthalmology

Exogenous Testosterone Use Increases the Risk of Central Serous Chorioretinopathy.

Journal francais d'ophtalmologie

Comparative efficacy of two different subthreshold yellow laser treatments for chronic central serous chorioretinopathy.

Aerospace medicine and human performance

Pachychoroid Neovasculopathy, Intravitreal Injection, and Implications for Aeromedical Decision Making.

Efficacy and Safety of Intravitreal Brolucizumab in Chronic Central Serous Chorioretinopathy: A Retrospective Cohort Study.

Journal of current ophthalmology

2024

Cyclodialysis Cleft following Intravitreal Injection; Case Report.

Investigative ophthalmology & visual science

Choroidal Vascular Fingerprints From Indocyanine Green Angiography Unveil Chorioretinal Disease State.

Association between Choroidal Vascular Hyperpermeability and Vortex Vein Anastomoses in Central Serous Chorioretinopathy.

Pregnancy as a risk factor for central serous chorioretinopathy: A systematic review and meta-analysis.

Diagnostic and Management Challenges in Atypical Central Serous Chorioretinopathy Mimicking Vogt-Koyanagi-Harada Disease: A Case Report.

Flat irregular pigment epithelium detachments in chronic central serous chorioretinopathy: a focus on choroidal changes.

Journal of personalized medicine

Efficacy of Intravitreal Brolucizumab for Chronic Central Serous Chorioretinopathy: A Pilot Study.

Micropulse laser therapy at 532, 577, and 810 nm for chronic central serous chorioretinopathy: a systematic review and Meta-analysis.

American journal of ophthalmology case reports

An autopsy case of bullous retinal detachment and hypopyon in a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia.

Archivos de la Sociedad Espanola de Oftalmologia

National study on the management of central serous chorioretinopathy.

Double layer sign in chorioretinal diseases: Clinical significance and implications from multimodal imaging.

Association of Central Serous Chorioretinopathy With Endogenous or Exogenous Corticosteroids: A Report of 2 Cases.

JCEM case reports

Efficacy of Topical Non-Selective and COX-2 Selective NSAIDs in Accelerating Resolution of Acute Central Serous Chorioretinopathy: A Retrospective Analysis.

Lasers in medical science

Efficacy of subliminal laser in chronic central serous chorioretinopathy: A 2.5-Year retrospective study.

Choroidal vascular hyperpermeability patterns in central serous chorioretinopathy correlate with microperimetry: CERTAIN study report 4.

European journal of ophthalmology

Clinical and imaging characteristics of central serous chorioretinopathy with subfoveal leak.

Diagnostics (Basel, Switzerland)

Resolved Central Serous Chorioretinopathy Mimicking Hydroxychloroquine Toxicity: A Case Series and Literature Review.

Advanced emergency nursing journal

Central Serous Chorioretinopathy and Diagnostic Challenges in Emergency Settings.

Three-Dimensional Choroidal Vessels Assessment in Fellow Eyes of Patients With Central Serous Chorioretinopathy.

Investigative ophthalmology & visual science

Evaluation of Reflectivities of RPE, ELM, EZ, and Their Relationship With Subretinal Fluid Properties in Central Serous Chorioretinopathy.

Classifying Subretinal Lucency: A Matter of Terminology and Resolution.

Predictive factors for the development of macular neovascularization in chronic central serous chorioretinopathy.

Morphological and Functional Outcomes in the Long-Term Natural Course of Peripapillary Pachychoroid Syndrome.

Klinische Monatsblatter fur Augenheilkunde

Visual Acuity May Inadequately Reflect the Vision-related Quality of Life in Patients with Chronic Chorioretinopathy Centralis Serosa.

Indian journal of ophthalmology

Central serous chorioretinopathy imaging biomarkers as potential indicators of response to subthreshold nanosecond laser.

Controversies and conundrums in pachychoroid spectrum disorders: A structured diagnostic approach.

A Lightweight CNN for Multiclass Retinal Disease Screening with Explainable AI.

Journal of imaging

A Novel Finding of Retinal Neovascularization Secondary to Chronic Central Serous Chorioretinopathy.

Taxane-associated retinopathy and radiation-induced optic neuropathy in a young female patient with metastatic breast cancer.

GMS ophthalmology cases

Choriocapillaris perfusion assessed using optical coherence tomography angiography depends on eye color and projection artifact removal.

Large Retinal Pigment Epithelium Tear in Central Serous Chorioretinopathy.

Ophthalmology. Retina

Ophthalmic surgery, lasers & imaging retina

Hyperreflective Foci in Blowout Pigmented Epithelium Detachment Secondary to Pachychoroid Mimicking Type 3 Macular Neovascularization.

Vision (Basel, Switzerland)

CPAP Use and Retinal Disease Risk in Obstructive Apnea: A Cohort Study.

Intraocular Pressure and Ocular Perfusion Pressure in Central Serous Chorioretinopathy.

[Long-term outcome after photodynamic therapy of persistent central serous chorioretinopathy].

Die Ophthalmologie

Approach to optic disc swelling with macular subretinal fluid and choroidal folds: a narrative review.

Respiratory investigation

Remarkable response to dupilumab in refractory allergic bronchopulmonary mycosis with a giant mucus plug due to Aspergillus udagawae.

Anatomical and Functional Outcomes of Anti-VEGF Therapy in Pachychoroid Neovasculopathy.

Journal of vitreoretinal diseases

Clinical Features and Optical Coherence Tomography Angiography in Neovascular Age-Related Macular Degeneration and Pachychoroid Neovasculopathy.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

Central Serous Chorioretinopathy occurs in High Frequency in Myelin Oligodendrocyte Glycoprotein Antibody Disease, Seropositive and Seronegative Neuromyelitis Optica Spectrum Disorders compared to Multiple Sclerosis and Healthy Controls.

Impact of the COVID-19 pandemic on the incidence and recurrence of central serous chorioretinopathy in Greece: a multicenter study.

The Journal of international medical research

A case of macular damage following micropulse laser treatment for central serous chorioretinopathy.

Global Incidence of Central Serous Chorioretinopathy: A Systematic Review, Meta-analysis, and Forecasting Study.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Changes in choroidal vessel morphology associated with fluid leakage in central serous chorioretinopathy; a comparison of OCTA and ICGA.

Evaluation of Choroidal Vein Distribution Pattern and Choroidal Vessel Parameters in Patients With Central Serous Chorioretinopathy Using Widefield ICGA and Widefield OCTA.

Deep learning in central serous chorioretinopathy.

Two-year treatment outcome of photodynamic therapy combined with anti-vascular endothelial growth factor therapy for pachychoroid neovasculopathy.

Association of central serous chorioretinopathy with single-nucleotide polymorphisms in Complement Factor H gene in a Chinese population.

Advances in experimental medicine and biology

Central Serous Chorioretinopathy.

Comprehensive analysis of pachyvessel morphology in central serous chorioretinopathy using multimodal imaging.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Characteristics of vortex vein in healthy eyes and fundus diseases imaged by ultra-widefield OCTA.

Evaluation of the therapeutic effects of smoking cessation on chronic central serous chorioretinopathy.

Acute bilateral retinal and choroidal detachment - A case report.

Research Progress in Artificial Intelligence for Central Serous Chorioretinopathy: A Systematic Review.

Dark Adaptometry Kinetics Differentiates Age-Related Macular Degeneration from Central Serous Chorioretinopathy.

Comparison of microvasculature between neovascular, non-neovascular chronic central serous chorioretinopathy cases and asymptomatic fellow eyes using swept-source optical coherence tomography angiography.

Photodynamic therapy-induced inflammation and adverse effects: An updated review.

Biomedical journal

Oman journal of ophthalmology

Central serous chorioretinopathy mimicking as choroidal hemangioma - A diagnostic challenge.

Treat and Extend Regimen of Aflibercept in the Treatment of Type 1 Choroidal Neovascularization Secondary to Chronic Central Serous Chorioretinopathy: Three-year Follow-Up.

Photodynamic therapy on chronic pathology during the post-COVID19 and worldwide shortage of verteporfin (Visudyne®) era.

A Comparative Study on the Prevalence of Helicobacter pylori Infection in Patients with Central Serous Chorioretinopathy versus a Control Population.

Treatment of central serous chorioretinopathy: new options for an old disease.

Successful surgical repair of a ruptured medial rectus muscle accompanied with serous chorioretinopathy.

Strabismus

Analysis of cytokine profiles in aqueous humor based on optical coherence tomography in pachychoroid spectrum diseases.

Influence of combined eplerenone, aflibercept and nepafenac therapy on central serous chorioretinopathy.

The Cochrane database of systematic reviews

Interventions for central serous chorioretinopathy: a network meta-analysis.

Reduction in choroidal thickness associated with the progression of pachychoroid spectrum diseases.

Eplerenone and Spironolactone for Chronic Central Serous Chorioretinopathy: A Systematic Review and Meta-Analysis.

Three-Dimensional Choroidal Contour Mapping in Healthy and Diseased Eyes.

Lasers in medical science

The results of subthreshold 577 nm yellow laser application using pascal laser system in patients with chronic central serous chorioretinopathy.

Case Report: Kyrieleis plaques in an unusual Behcet's disease uveitis.

Frontiers in medicine

Delayed Onset of Central Serous Chorioretinopathy following Corticosteroid Treatment for Giant Cell Arteritis: A Case Report.

Posterior scleritis misdiagnosed as central serous chorioretinopathy: Case report.

Indian journal of ophthalmology

Central serous chorioretinopathy and autonomic dysfunction.

Indian journal of ophthalmology

Evaluation of anterior scleral thickness in eyes with central serous chorioretinopathy.

Real-world use of a hydrophilic curcumin-based oral formulation in the management of macular oedema: a collection of clinical experiences.

Drugs in context

Fractal analysis for OCT-A images of central serous chorioretinopathy.