Optimizing the Use of Serum Immunofixation for the Detection of Monoclonal Components in Hypogammaglobulinemia: Insights From a Tertiary-Care Biochemistry Laboratory.

CFP1-mediated H3K4me3 broad domains control early B cell lineage fate determination.

Tear Protein Alteration in Dogs with Keratoconjunctivitis Sicca.

BAFF-R Expression as a Potential Biomarker Associated with COVID-19 Vaccine Non-Responsiveness in Antibody-Deficient Patients.

Primary Humoral Immunodeficiencies and Bronchiectasis in Adults.

Characterization of a factor VIII/immunoglobulin heavy chain μ double-knockout mouse model of hemophilia A for long-term exposure to factor VIII proteins.

Polymerase theta repairs persistent G1-induced DNA breaks in S-phase during class switch recombination.

IL-7 promotes the formation of DNA double strand breaks and DNA repair in murine pro-B cells.

[The Relationship between Ig Class Switch Recombination and MMR Protein, Microsatellite Phenotype in Extranodal Marginal Zone Lymphoma of Mucosa-associated Lymphoid Tissue].

Membranous nephropathy as a segmental pattern with solitary immunoglobulin A deposition: a case report.

IgG4-Related Disease: Emerging Roles of Novel Genetic Variants, Immune Cell Subsets and Therapeutic Targets.

CST Is Epistatic With Shieldin to Limit DNA Double-Strand Break End Resection and Promote Repair During Igh Class Switch Recombination.

Effects of two different variants in the MAGT1 gene on B cell subsets, platelet function, and cell glycome composition.

Group A streptococcal SpeB modifies IgA through targeting regions other than the hinge.

Proteomics Reveals That Vitamin D Deficiency Leads to Immunoglobulin Abnormalities and Immune Dysregulation in Patients with Post-COVID-19 Condition.

Deficiency of adenosine deaminase 2 skews adaptive immune repertoires toward specific sets of T- and B-cell receptors.

Heavy Chain Disease with Cystic Lung Disease Presenting as Recurrent Spontaneous Pneumothorax in a Young Adult.

Papillary renal cell carcinoma revisited: impact of the World Health Organization 2022 classification on prognostication.

Progressive polyadenylation and m6A modification of Ighg1 mRNA maintain IgG1 antibody homeostasis in antibody-secreting cells.

Zn0-Induced Cytotoxicity and Mitochondrial Stress in Microglia: Implications of the Protective Role of Immunoglobulin G In Vitro.

UPF1 plays critical roles in early B cell development.

Ki67 deficiency impedes chromatin accessibility and BCR gene rearrangement.

Generation of nanobodies from transgenic 'LamaMice' lacking an endogenous immunoglobulin repertoire.

Qualitative Immunoglobulin Deficiency Causes Bacterial Infections in Patients with STAT1 Gain-of-Function Mutations.

Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma.

B-cells absence in patients diagnosed as inborn errors of immunity: a registry-based study.

BRD2 promotes antibody class switch recombination by facilitating DNA repair in collaboration with NIPBL.

Lycopene Alleviates Endoplasmic Reticulum Stress in Steatohepatitis through Inhibition of the ASK1-JNK Signaling Pathway.

Influence of pre-B cell receptor deficiency on the immunoglobulin repertoires in peripheral blood B cells before and after immunization.

Endogenous complement-activating IgM is not required for primary antibody responses but promotes plasma cell differentiation and secondary antibody responses to a large particulate antigen in mice.

Spliceosome component PHD finger 5A is essential for early B lymphopoiesis.

Pozelimab: First Approval.

Platelet-localized ST6Gal1 does not impact IgG sialylation.

Impaired Response to Polysaccharide Vaccine in Selective IgE Deficiency.

The RNA-binding protein hnRNP F is required for the germinal center B cell response.

Clonal relationships of memory B cell subsets in autoimmune mice.

The IgH Eµ-MAR regions promote UNG-dependent error-prone repair to optimize somatic hypermutation.

Sequencing the B Cell Receptor Repertoires of Antibody-Deficient Individuals With and Without Infection Susceptibility.

B-1 plasma cells require non-cognate CD4 T cell help to generate a unique repertoire of natural IgM.

The establishment of B cell-deficient Igh-J KO mouse model by gene editing and efficacy evaluation.

The CMV-encoded G protein-coupled receptors M33 and US28 play pleiotropic roles in immune evasion and alter host T cell responses.

Senataxin and RNase H2 act redundantly to suppress genome instability during class switch recombination.

Human type I IFN deficiency does not impair B cell response to SARS-CoV-2 mRNA vaccination.

Two pediatric oncologic cases of hypereosinophilic syndrome and review of the literature.

Development and characterization of a CRISPR/Cas9-mediated RAG1 knockout chicken model lacking mature B and T cells.

Global patterns of antigen receptor repertoire disruption across adaptive immune compartments in COVID-19.

TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity.

Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in Exo1D173A mice.

Hypovitaminosis D Is Prevalent in Patients With Renal AL Amyloidosis and Associated With Renal Outcome.

SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination.

RNA exosome drives early B cell development via noncoding RNA processing mechanisms.

The mammalian SKIV2L RNA exosome is essential for early B cell development.

Organization and Complexity of the Yak (Bos Grunniens) Immunoglobulin Loci.

Human activation-induced deaminase lacks strong replicative strand bias or preference for cytosines in hairpin loops.

Allergic asthma aggravates angiotensin Ⅱ-induced cardiac remodeling in mice.

IRF4 Has a Unique Role in Early B Cell Development and Acts Prior to CD21 Expression to Control Marginal Zone B Cell Numbers.

UnAIDed Class Switching in Activated B-Cells Reveals Intrinsic Features of a Self-Cleaving IgH Locus.

Intrathymic differentiation of natural antibody-producing plasma cells in human neonates.

Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release.

Aging and Hypercholesterolemia Differentially Affect the Unfolded Protein Response in the Vasculature of ApoE-/- Mice.

Immunoglobulin A nephropathy in a patient with an MYH9 -related disorder.

Fcγ receptor activation mediates vascular inflammation and abdominal aortic aneurysm development.

Effect of Clp protease from Corynebacterium glutamicum on heterologous protein expression.

Normal IgH Repertoire Diversity in an Infant with ADA Deficiency After Gene Therapy.

Incorporation of TePhe into Expressed Proteins is Minimally Perturbing.

The Traf2DNxBCL2-tg Mouse Model of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Recapitulates the Biased IGHV Gene Usage, Stereotypy, and Antigen-Specific HCDR3 Selection of Its Human Counterpart.

Consensus Recommendations for MRD Testing in Adult B-Cell Acute Lymphoblastic Leukemia in Ontario.

Deficiency of WFS1 leads to the impairment of AVP secretion under dehydration in male mice.

Polymorphisms in canine immunoglobulin heavy chain gene cluster: a double-edged sword for diabetes mellitus in the dog.

Noncoding RNA processing by DIS3 regulates chromosomal architecture and somatic hypermutation in B cells.

Loop extrusion mediates physiological Igh locus contraction for RAG scanning.

Salivary Carbohydrate-Deficient Transferrin in Alcohol- and Nicotine-Dependent Males.

Assigning immunoglobulin class from single-cell transcriptomes in IgA1-secreting versus membrane subpopulations.

CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining.

Prognostic models for newly-diagnosed chronic lymphocytic leukaemia in adults: a systematic review and meta-analysis.

An RTEL1 Mutation Links to Infantile-Onset Ulcerative Colitis and Severe Immunodeficiency.

Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation.

Class switching and high-affinity immunoglobulin G production by B cells is dispensable for the development of hypertension in mice.

Impact of T-cell receptor and B-cell receptor repertoire on the recurrence of early stage lung adenocarcinoma.

RNA-binding motifs of hnRNP K are critical for induction of antibody diversification by activation-induced cytidine deaminase.

Noncoding RNA transcription alters chromosomal topology to promote isotype-specific class switch recombination.

Targeting CD38-Expressing Multiple Myeloma and Burkitt Lymphoma Cells In Vitro with Nanobody-Based Chimeric Antigen Receptors (Nb-CARs).

B Cell and CD4 T Cell Interactions Promote Development of Atherosclerosis.

Gamma heavy chain disease (γ-HCD) as iatrogenic immunodeficiency- associated lymphoproliferative disorder: Possible emergent subtype of rheumatoid arthritis-associated γ-HCD.

Delineating Human B Cell Precursor Development With Genetically Identified PID Cases as a Model.

ERG Controls B Cell Development by Promoting Igh V-to-DJ Recombination.

In Vivo Analysis of Human Immune Responses in Immunodeficient Rats.

Heavy Chain Deposition Disease: Clinicopathologic Characteristics of a Chinese Case Series.

Fundamental roles of chromatin loop extrusion in antibody class switching.

Supplementation With the Sialic Acid Precursor N-Acetyl-D-Mannosamine Breaks the Link Between Obesity and Hypertension.

Disruption of the preB Cell Receptor Complex Leads to Decreased Bone Mass.

EuroFlow-Based Flowcytometric Diagnostic Screening and Classification of Primary Immunodeficiencies of the Lymphoid System.

Chromosome dynamics near the sol-gel phase transition dictate the timing of remote genomic interactions.

Prognostic markers for immunodeficiency-associated primary central nervous system lymphoma.

MZB1 promotes the secretion of J-chain-containing dimeric IgA and is critical for the suppression of gut inflammation.

The Heterogeneous Pathogenesis of Selective Immunoglobulin A Deficiency.

IL1R8 Deficiency Drives Autoimmunity-Associated Lymphoma Development.

Pten controls B-cell responsiveness and germinal center reaction by regulating the expression of IgD BCR.

Apurinic/apyrimidinic endonuclease 1 (APE1) is dispensable for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation in the immunoglobulin gene.

Defects in memory B-cell and plasma cell subsets expressing different immunoglobulin-subclasses in patients with CVID and immunoglobulin subclass deficiencies.

Will Attention by Vaccine Developers to the Host's Nuclear Hormone Levels and Immunocompetence Improve Vaccine Success?

Skewed B cell receptor repertoire and reduced antibody avidity in patients with DOCK8 deficiency.

Impaired Expression of Rearranged Immunoglobulin Genes and Premature p53 Activation Block B Cell Development in BMI1 Null Mice.

3'Igh enhancers hs3b/hs4 are dispensable for Myc deregulation in mouse plasmacytomas with T(12;15) translocations.

The circulating immunoglobulins negatively impact on the parasite clearance in the liver of Leishmania donovani-infected mice via dampening ROS activity.

3'RR and 5'Eμ immunoglobulin heavy chain enhancers are independent engines of locus remodeling.

The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination.

Deletion of Adam6 in Mus musculus leads to male subfertility and deficits in sperm ascent into the oviduct.

Identification of Distinct Unmutated Chronic Lymphocytic Leukemia Subsets in Mice Based on Their T Cell Dependency.

Comparison of Common Monogenic Defects in a Large Predominantly Antibody Deficiency Cohort.

Deletion of the immunoglobulin heavy chain 3' regulatory region super-enhancer affects somatic hypermutation in B1 B cells.

No Overt Clinical Immunodeficiency Despite Immune Biological Abnormalities in Patients With Constitutional Mismatch Repair Deficiency.

IL-7 Enables Antibody Responses to Bacterial Polysaccharides by Promoting B Cell Receptor Diversity.

IgA kappa light and heavy chain deposition disease in multiple myeloma.

CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning.

Myosin IIa Promotes Antibody Responses by Regulating B Cell Activation, Acquisition of Antigen, and Proliferation.

Recombination activity of human recombination-activating gene 2 (RAG2) mutations and correlation with clinical phenotype.

RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination.

Diversity of Immunoglobulin (Ig) Isotypes and the Role of Activation-Induced Cytidine Deaminase (AID) in Fish.

Human Immunodeficiency Virus Tat Protein Aids V Region Somatic Hypermutation in Human B Cells.

Molecular mechanisms of missense mutations that generate ectopic N-glycosylation sites in coagulation factor VIII.

DNA double-strand break response factors influence end-joining features of IgH class switch and general translocation junctions.

Age-associated B cells expanded in autoimmune mice are memory cells sharing H-CDR3-selected repertoires.

Distorted antibody repertoire developed in the absence of pre-B cell receptor formation.

Phosphorylation promotes activation-induced cytidine deaminase activity at the Myc oncogene.

CCCTC-Binding Factor Locks Premature IgH Germline Transcription and Restrains Class Switch Recombination.

A murine Ig light chain transgene reveals IGKV3 gene contributions to anti-collagen types IV and II specificities.

[Colombian Guidelines of clinical practice for the use of immunoglobulins in the treatment of replacement and immunomodulation].

Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses.

Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance.

Characterization of T and B cell repertoire diversity in patients with RAG deficiency.

sIgM-FcμR Interactions Regulate Early B Cell Activation and Plasma Cell Development after Influenza Virus Infection.

Absence of γ-Chain in Keratinocytes Alters Chemokine Secretion, Resulting in Reduced Immune Cell Recruitment.

First report of real-time monitoring of coagulation function potential and IgG subtype of anti-FVIII autoantibodies in a child with acquired hemophilia A associated with streptococcal infection and amoxicillin.

An Expanded Role for HLA Genes: HLA-B Encodes a microRNA that Regulates IgA and Other Immune Response Transcripts.

B cells do not have a major pathophysiologic role in acute ischemic stroke in mice.

Self-reactive VH4-34-expressing IgG B cells recognize commensal bacteria.

CD11b regulates antibody class switching via induction of AID.

Immunoglobulin M, a novel molecule of myocardial cells of mice.

Eμ and 3'RR IgH enhancers show hierarchic unilateral dependence in mature B-cells.

Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells.

53BP1 Contributes to Igh Locus Chromatin Topology during Class Switch Recombination.

VH1 Family Immunoglobulin Repertoire Sequencing after Allogeneic Hematopoietic Stem Cell Transplantation.

Pro-B cells propagated in stromal cell-free cultures reconstitute functional B-cell compartments in immunodeficient mice.

Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program.

Somatic Mutations Modulate Autoantibodies against Galactose-Deficient IgA1 in IgA Nephropathy.

MBD4 Facilitates Immunoglobulin Class Switch Recombination.

Regulated large-scale nucleosome density patterns and precise nucleosome positioning correlate with V(D)J recombination.

Efficient role of IgH 3' regulatory region deficient B-cells in the development of oil granulomas.

Antigen presentation by B cells guides programing of memory CD4+ T-cell responses to a TLR4-agonist containing vaccine in mice.

Gata3 restrains B cell proliferation and cooperates with p18INK4c to repress B cell lymphomagenesis.

Clathrin light chains' role in selective endocytosis influences antibody isotype switching.

Immunoglobulin A nephropathy: a pathophysiology view.

Interferon regulatory factor 4 attenuates Notch signaling to suppress the development of chronic lymphocytic leukemia.

YY1 Is Required for Germinal Center B Cell Development.

Germline Gene Editing in Chickens by Efficient CRISPR-Mediated Homologous Recombination in Primordial Germ Cells.

Identification of Liver Epithelial Cell-derived Ig Expression in μ chain-deficient mice.

GNA13 loss in germinal center B cells leads to impaired apoptosis and promotes lymphoma in vivo.

Soluble B-Cell Maturation Antigen Mediates Tumor-Induced Immune Deficiency in Multiple Myeloma.

Cohort of Iranian Patients with Congenital Agammaglobulinemia: Mutation Analysis and Novel Gene Defects.

Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination.

Antibodies from donor B cells perpetuate cutaneous chronic graft-versus-host disease in mice.

Immunoglobulin K light chain deficiency: A rare, but probably underestimated, humoral immune defect.

B-Cell-Deficient and CD8 T-Cell-Depleted Gnotobiotic Pigs for the Study of Human Rotavirus Vaccine-Induced Protective Immune Responses.

Prevalence and characteristics of central nervous system involvement by chronic lymphocytic leukemia.

Non-canonical uracil processing in DNA gives rise to double-strand breaks and deletions: relevance to class switch recombination.

Hotspots for Vitamin-Steroid-Thyroid Hormone Response Elements Within Switch Regions of Immunoglobulin Heavy Chain Loci Predict a Direct Influence of Vitamins and Hormones on B Cell Class Switch Recombination.

Combined deletion of Xrcc4 and Trp53 in mouse germinal center B cells leads to novel B cell lymphomas with clonal heterogeneity.

B cell development in chromosome 22q11.2 deletion syndrome.

Isolation and Characterization of a Murine Spontaneous High-Grade Follicular Lymphoma with Restricted In Vivo Spreading--a Model for Lymphatic Metastasis Via the Mesentery.

Atherosclerosis Susceptibility in Mice Is Independent of the V1 Immunoglobulin Heavy Chain Gene.

Identification of checkpoints in human T-cell development using severe combined immunodeficiency stem cells.

Analysis of IgM antibody production and repertoire in a mouse model of Sjögren's syndrome.

Generation of B cell-deficient pigs by highly efficient CRISPR/Cas9-mediated gene targeting.

Patient-derived heavy chain antibody targets cell surface HSP90 on breast tumors.

Indole-3-Carbinol Synergizes with and Restores Fludarabine Sensitivity in Chronic Lymphocytic Leukemia Cells Irrespective of p53 Activity and Treatment Resistances.

B Cell-Intrinsic Expression of the HuR RNA-Binding Protein Is Required for the T Cell-Dependent Immune Response In Vivo.

IgH sequences in common variable immune deficiency reveal altered B cell development and selection.

Enabling Low Cost Biopharmaceuticals: A Systematic Approach to Delete Proteases from a Well-Known Protein Production Host Trichoderma reesei.

HC-HA/PTX3 Purified From Amniotic Membrane Promotes BMP Signaling in Limbal Niche Cells to Maintain Quiescence of Limbal Epithelial Progenitor/Stem Cells.

Paraproteinemic Keratopathy: The Expanding Diversity of Clinical and Pathologic Manifestations.

De novo DNA Methyltransferases Dnmt3a and Dnmt3b regulate the onset of Igκ light chain rearrangement during early B-cell development.

Bruton's Tyrosine Kinase Synergizes with Notch2 To Govern Marginal Zone B Cells in Nonobese Diabetic Mice.

The IgH 3' regulatory region influences lymphomagenesis in Igλ-Myc mice.

Elucidation of IgH 3' region regulatory role during class switch recombination via germline deletion.

Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase.

B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.

Epstein-Barr virus-positive diffuse large B-cell lymphoma in children: a disease reminiscent of Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly.

Camelid single-domain antibody fragments: Uses and prospects to investigate protein misfolding and aggregation, and to treat diseases associated with these phenomena.

Histone acetyltransferase p300/CBP-associated factor is an effective suppressor of secretory immunoglobulin synthesis in immature B cells.

Molecular basis for antagonistic activity of anifrolumab, an anti-interferon-α receptor 1 antibody.