Deleterious NKAP Mutations Are Associated with Musculoskeletal Abnormalities in Hemizygous Males and Skewed X Chromosome Inactivation in Heterozygous Females.

Enhanced Peripartum Hemostatic Management Does Not Decrease Postpartum Hemorrhage Incidence in Hemophilia Carriers: the Pregnancy and Inherited Bleeding Disorders study (PRIDES).

A novel dinucleotide variant at 5' splice sites in the F8 gene causes exon 19 skipping in a Chinese family with hemophilia A.

Updated Egyptian national guidelines for management of hemophilia A in children & adolescents.

F8 gene variants influence the response to desmopressin in hemophilia A carriers.

Application of capillary gel electrophoresis in detection of Factor VIII gene intron 22 inversion of hemophilia A.

Management of Pregnancy, Delivery, and Postpartum in Italian Carriers and Women With Haemophilia A and B.

Hybridization capture long-read sequencing and de novo assembly of homologous haplotypes: a comprehensive hemophilia test.

ImpaHCta-Haemophilia Carriers Quality of Life Assessment.

Prevalence of hemophilia in women and girls in Burkina Faso.

Factor activity levels and bleeding scores in hemophilia carriers: apparent paradoxes.

Comorbidity and Mortality in Men and Women With Haemophilia in Three Nordic Countries-Comparisons to Matched Controls.

Lipopolysaccharide-binding protein functions as factor VIII inhibitor in bullous pemphigoid associated with acquired hemophilia A.

Discrepancy between one-stage clotting and chromogenic factor VIII activity in women with hemophilia A and hemophilia A carriers: a retrospective clinical study.

Genetic testing for children at risk to be hemophilia carriers.

Development of a Single-Tube Reverse Transcription Real-Time PCR Assay for Diagnosis of F8 Intron 22 Inversion in Patients and Carriers of Haemophilia A.

Noninversion Variants in Sporadic Hemophilia A Originate Mostly from Females.

An investigation of a hemophilia A female with heterozygous intron 22 inversion and skewed X chromosome inactivation.

Genomic Landscape of Chromosome X Factor VIII: From Hemophilia A in Males to Risk Variants in Females.

Investigation of a hemophilia family with one female hemophilia A patient and 12 male hemophilia A patients.

The history of women and hemophilia: a narrative review of evolving beliefs and testing practices.

Clot waveform analysis in hemophilia carriers.

Design of an international, phase IV, open-label study of simoctocog alfa in women/girls with hemophilia A undergoing surgery (NuDIMENSION).

Assessment of joint health in females with haemophilia: The carriers ultrasound project (CUP) study.

Macrophage membrane-encapsulated miRNA nanodelivery system for the treatment of hemophilic arthritis.

A Comparative Analysis of the Bleeding Profile and Quality of Life Among Women With Hemophilia Genotype Compared to Other Bleeding Disorders.

Haemophilia testing of young girls in Canada: Describing the current recommendations for factor level and genetic testing and the experiences of Canadian parents.

The prevalence of Hemophilia A in males in Africa: evidence from a systematic review and meta-analysis.

Clinical, Laboratory, Molecular, and Reproductive Aspects of Combined Deficiency of Factors V and VIII.

Large deletions and small insertions and deletions in the factor VIII gene predict unfavorable immune tolerance induction outcome in people with severe hemophilia A and high-responding inhibitors.

Proactive systematic hemophilia carrier screening: a step toward gender equity in hemophilia care.

Characterization of zebrafish coagulation cofactors Fviii and Fv mutants and modeling hemophilia A and factor V deficiency.

Heterozygous large deletion mimicking homozygous substitution in MCFD2 in a patient with combined Factor V and Factor VIII deficiency.

Clinical and molecular characteristics of hemophilia A affected individuals and carriers: A 24 years experience from three centers.

[Treatment of haemophilia in Austria].

Comprehensive genomic filtering algorithm to expose the cause of skewed X chromosome inactivation. The proof of concept in female haemophilia expression.

Application of machine learning approaches for predicting hemophilia A severity.

Bleeding risk in hemophilia A and B carriers: comparison of factor levels determined using chronometric and chromogenic assays.

Origin of pathogenic variant and mosaicism in families with a sporadic case of haemophilia B.

Clinical Analysis and Mental Health Survey of Hemophilia Carriers: a Cross-sectional Study.

Women and girls with inherited bleeding disorders: Focus on haemophilia carriers and heavy menstrual bleeding.

[Successful immunosuppressive therapy in female hemophilia A developing inhibitor after perioperative administration of factor VIII products].

Test-retest reliability of a mobile application of the patient reported outcomes burdens and experiences (PROBE) study.

The underevaluated impacts of the therapeutic revolution of hemophilia on women and girls.

Prenatal diagnosis and genetic analysis of novel missense mutation in FVIII gene.

The psychosocial impact of haemophilia from patients' and caregivers' point of view: The results of an Italian survey.

Specific serum biomarkers to assess the bone health in a group of hemophilia A carriers: Data from the CAR.BONE study.

Hemophilia A in a litter of Border Collies caused by a one base pair deletion in the F8 gene.

National strategic advocacy to manage patients with inherited bleeding disorders in low and lower-middle income countries.

Adherence tool for prophylactic haemophilia treatment in adult and adolescent patients: A systematic review and meta-analysis protocol.

Management of pregnant women who have bleeding disorders.

Renal inflammatory myofibroblastic tumor coexisting with hemophilia A carrier: a case report and literature review.

Factor VIII antibody immune complexes modulate the humoral response to factor VIII in an epitope-dependent manner.

Building a haemophilia-specific navigator in Epic® Electronic Health Records: Single-centre preliminary experience.

Factor activity levels and bleeding scores in pediatric hemophilia carriers enrolled in the ATHNdataset.

Association of Genetic Variant FVIII Gene and Factor VIII: A Pilot Study Among Hemophilia A Female Relatives in Saudi Arabia.

Psychological and cognitive factors involved in decision-making process of haemophilia carriers in reproductive choices.

Four Decades of Carrier Detection and Prenatal Diagnosis in Hemophilia A: Historical Overview, State of the Art and Future Directions.

A frameshift deletion in F8 associated with hemophilia A in Labrador Retriever dogs.

Real-world analysis of patients with haemophilia A and haemophilia A carriers in the United States: Demographics, clinical characteristics and costs.

A novel F8 variant in a Chinese hemophilia A family and involvement of X-chromosome inactivation: A case report.

The length of the sanitary napkins can be used as a handier index than pictorial blood loss assessment chart to predict the heavy menstrual bleeding.

Von Willebrand Disease, Hemophilia, and Other Inherited Bleeding Disorders in Pregnancy.

Molecular pathogenesis of a novel Met394Thr variant causing hemophilia B.

Thromboembolic Disease in Haemophilic Patients Undergoing Major Orthopaedic Surgery: Is Thromboprophylaxis Mandatory?

Management of pregnant female with Haemophilia-A: A case report.

Separate roles of LMAN1 and MCFD2 in ER-to-Golgi trafficking of FV and FVIII.

A Novel Deletion Mutation of the F8 Gene for Hemophilia A.

Preimplantation genetic testing (PGT) for hemophilia A: Experience from one center.

Mechano-covalent protection of coagulation factor VIII by von Willebrand factor.

Prophylaxis use of clotting factor replacement products in people with non-severe haemophilia: A review of the literature.

Prenatal diagnosis for hemophilia A (intron 22 inversion) reveals a rare association with Klinefelter syndrome with diagnostic difficulties in molecular interpretation.

Managing Pregnant Women with Hemophilia and von Willebrand Disease: How Do We Provide Optimum Care and Prevent Complications?

Delivery of Cas9-guided ABE8e into stem cells using poly(l-lysine) polypeptides for correction of the hemophilia-associated FIX missense mutation.

[Analysis of genetic variant in a Chinese pedigree with hereditary factor VIII deficiency].

"Haemophilia A" - Presenting with oral squamous cell carcinoma diagnosis and management strategies.

Investigation of the Bleeding Tendency in Sudanese Female Carriers of Hemophilia B.

Results of genetic analysis of 11 341 participants enrolled in the My Life, Our Future hemophilia genotyping initiative in the United States.

"A new hemophilia carrier nomenclature to define hemophilia in women and girls: Communication from the SSC of the ISTH": Comment.

"A New Hemophilia Carrier Nomenclature to define hemophilia in women and girls: Communication from the SSC of the ISTH": Reply to comment.

Health issues in women and girls affected by haemophilia with a focus on nomenclature, heavy menstrual bleeding, and musculoskeletal issues.

Next-generation sequencing of von Willebrand factor and coagulation factor VIII genes: a cross-sectional study in Croatian adult patients diagnosed with von Willebrand disease.

Bone health in haemophilia carriers and persons with von Willebrand disease: A large database analysis.

Management and outcomes of mild hemophiliacs and hemophilia carriers during pregnancy and peripartum period: a hemophilia treatment center experience in the United States.

Mothers' strategies for supporting daughters who are potential haemophilia carriers.

The Lesson Learned from the New c.2547-1G > T Mutation Combined with p.R854Q: When a Type 2N Mutation Reveals a Quantitative von Willebrand Factor Defect.

The views of women with bleeding disorders: Results from the Cinderella study.

The effect of carriers' reproductive choices and pregnancy history on sporadic severe haemophilia: A 20-year retrospective study through a regional registry.

[Analysis of a patient with severe Hemophilia A due to a large duplication of F8 gene].

Determining common variants in patients with haemophilia A in South Vietnam and screening female carriers in their family members.

Percutaneous left atrial appendage closure in patients with primary hemostasis disorders and atrial fibrillation.

The role of genetics in the diagnosis and treatment of haemorrhagic diathesis: a historical perspective.

Descriptive analysis of bleeding symptoms in haemophilia carriers enrolled in the ATHNdataset.

Type 2N VWD: Conclusions from the Spanish PCM-EVW-ES project.

Molecular Mechanisms of Skewed X-Chromosome Inactivation in Female Hemophilia Patients-Lessons from Wide Genome Analyses.

Evaluation of ISTH-BAT as a predictor for factor deficiency in haemophilia carriers: a single-centre experience.

A qualitative study on the experiences of haemophilia carriers before, during and after pregnancy.

Regulation and importance of factor VIII levels in hemophilia A carriers.

Hemophilia A (Factor VIII Deficiency).

Identification of F8 rearrangements in carrier and non-carrier mothers of haemophilia A patients.

Hemophilia A and C in a female: The first case report in literature.

A new hemophilia carrier nomenclature to define hemophilia in women and girls: Communication from the SSC of the ISTH.

Haemophilia Carriers Experience Study (CARES): A mixed method exploration into the experience of women who are carriers of Haemophilia.

[The management strategy for von Willebrand disease].

[Analysis of gene inversion in Hemophilia A by Nanopore sequencing].

Consensus on hemophilia in Mexico.

Maternal and neonatal bleeding complications in relation to peripartum management in hemophilia carriers: A systematic review.

Genetic analysis of carrier status in female members of Japanese hemophilia families.

Case Report: Identification of a de novo Missense Mutation in the F8 Gene, p.(Phe690Leu)/c.2070C > A, Causing Hemophilia A: A Case Report.

Factor VIII levels and bleeding according to factor 8 (F8) mutation in pregnant carriers of haemophilia A: a multicentre retrospective cohort study.

Delivery and neuraxial technique outcomes in patients with hemophilia and in hemophilia carriers: a systematic review.

Development of a Specific Monoclonal Antibody to Detect Male Cells Expressing the RPS4Y1 Protein.

Von Willebrand disease type 2N: An update.

A SINE Insertion in F8 Gene Leads to Severe Form of Hemophilia A in a Family of Rhodesian Ridgebacks.

Evaluation of bleeding symptoms and laboratory parameters related to bleeding in sisters of patients with hemophilia A and B.

Women and girls with haemophilia and bleeding tendencies: Outcomes related to menstruation, pregnancy, surgery and other bleeding episodes from a retrospective chart review.

Women with haemophilia also exist.

Hemophilia carriers and women with coagulopathies: challenges in the occupational arena.

Hemophilia carriers: quality of life and management at different life stages.

Carriers of haemophilia: pregnancy, childbirth and postpartum.

Prenatal diagnostic techniques and IVF in patients with coagulopathies.

State of the art of genetic studies in hemophilia carriers.

General concepts on hemophilia A and on women carrying the disease.

Droplet digital PCR and mile-post analysis for the detection of F8 int1h inversions.

Genetic causes of haemophilia in women and girls.

Mutation analysis in the F8 gene in 485 families with haemophilia A and prenatal diagnosis in China.

Genetic analysis for carrier diagnosis in hemophilia A and B in the Mexican population: 25 years of experience.

X Chromosome inactivation: a modifier of factor VIII and IX plasma levels and bleeding phenotype in Haemophilia carriers.

Factor VIII Intron 22 Inversion in Severe Hemophilia A Patients in Palestine.

Women and girls with haemophilia: Lessons learned.

Haemophilia A/B carriers: haemorrhagic burden of disease and open issues.

Novel F8 and F9 gene variants from the PedNet hemophilia registry classified according to ACMG/AMP guidelines.

Bleeding complications during pregnancy and delivery in haemophilia carriers and their neonates in Western France: An observational study.

Postpartum bleeding in women with inherited bleeding disorders: a matched cohort study.

How I manage pregnancy in carriers of hemophilia and patients with von Willebrand disease.

Unravelling the knowledge, beliefs, behaviours and concerns of Persons with Haemophilia and their carriers in Senegal.

A study of dedicated haemophilia carrier clinics in the United States: Prevalence, services offered and barriers to development.

The diagnosis of a haemophilia A carrier over 2 decades.

Registry of patients with congenital bleeding disorders and COVID-19 in Madrid.

Role of Small Intestine and Gut Microbiome in Plant-Based Oral Tolerance for Hemophilia.

Six molecular patterns leading to hemophilia A phenotype in 18 females from Poland.

Identification and expression of a novel heterozygous frameshift mutation in FGA accounting for congenital hypofibrinogenemia in carriers of severe hemophilia A.

Perinatal Management of Haemophilia.

Genetics of equine bleeding disorders.

The experiences and attitudes of hemophilia carriers around pregnancy: A qualitative systematic review.

Genetic mosaicism in haemophilia: A practical review to help evaluate the risk of transmitting the disease.

Escape or Fight: Inhibitors in Hemophilia A.

A Closed-Tube Nested Quantitative PCR Assay for Rapid Detection of Intron 22 Inversions in the Factor VIII Gene.

Detection of F8 int22h inversions using digital droplet PCR and mile-post assays.

Noninvasive prenatal diagnosis of hemophilia A by a haplotype-based approach using cell-free fetal DNA.

Identification of the Intron 22 and Intron 1 Inversions of the Factor VIII Gene in Iraqi Kurdish Patients With Hemophilia A.

In Silico Study of Correlation between Missense Variations of F8 Gene and Inhibitor Formation in Severe Hemophilia A.

EHL-FIX in haemophilia B carriers with FIX deficiency.

Hemophilia A in Females: Considerations for Clinical Management.

Can we compare haemophilia carriers with clotting factor deficiency to male patients with mild haemophilia?

Bone health in symptomatic carriers of haemophilia A: a protocol for a multicentre prospective matched-cohort study.

Maternal and neonatal outcomes in carriers of haemophilia A and B: A Swedish Medical Birth Register study.

Bleeding assessment in haemophilia carriers-High rates of bleeding after surgical abortion and intrauterine device placement: A multicentre study in China.

Mothers' intentions and behaviours regarding providing risk communication to their daughters about their possibility of being haemophilia carriers: A qualitative study.

Joint comorbidities among Swedish carriers of haemophilia: A register-based cohort study over 22 years.

Development and evaluation of appropriate, culturally adapted educational tools for Ivoirian patients with haemophilia, haemophilia carriers and their families.

The national blueprint for pregnancy/birth longitudinal cohorts to study factor VIII immunogenicity: NHLBI State of the Science (SOS) Workshop on factor VIII inhibitors.

Compensated pathogenic variants in coagulation factors VIII and IX present complex mapping between molecular impact and hemophilia severity.

Total hip arthroplasty for a woman with hemophilia A -case report.

Application of Indirect Linkage Analysis for Carrier Detection of Hemophilia A in Kurdistan Region of Iraq: Usefulness of Intron 18 BclI T>A, Intron 19 HindIII C>T, and IVS7 nt27 G>A Markers.

[HEMOPHILIA - A ROYAL DISEASE IN THE HOLY LAND].

Preventing lives affected by hemophilia: A mixed methods study of the views of adults with hemophilia and their families toward genetic screening.

Mode of delivery in hemophilia: vaginal delivery and Cesarean section carry similar risks for intracranial hemorrhages and other major bleeds.

Hemophilia carrier's awareness, diagnosis, and management in emerging countries: a cross-sectional study in Côte d'Ivoire (Ivory Coast).

Literature review and clinical observation of acquired idiopathic hemophilia with a new missense mutation in the factor VIII gene (His2026Arg).

Splicing analysis of 26 F8 nucleotide variations using a minigene assay.

Inverse PCR to perform long-distance haplotyping: main applications to improve preimplantation genetic diagnosis in hemophilia.

The invisible child: Sibling experiences of growing up with a brother with severe haemophilia-An interpretative phenomenological analysis.

A decreased and less sustained desmopressin response in hemophilia A carriers contributes to bleeding.

Use of two complementary new molecular techniques, next-generation sequencing and droplet digital PCR, for diagnosis of an F8 gene deletion and subsequent carrier analysis in a family with haemophilia A: A Case Report.

Hemophilia B in a female with intellectual disability caused by a deletion of Xq26.3q28 encompassing the F9.

Consensus Statement of the Indian Academy of Pediatrics in Diagnosis and Management of Hemophilia.

Inherited Bleeding Disorders in the Obstetric Patient.

Optimizing bleed prevention throughout the lifespan: Womb to Tomb.

Genotypes, phenotypes and whole genome sequence: Approaches from the My Life Our Future haemophilia project.

Postpartum haemorrhage in an unselected cohort of carriers of haemophilia.

Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-α pathway.

Screening of haemophilia carriers in moderate and severe haemophilia A and B: Prevalence and determinants.

An intronic mutation c.6430-3C>G in the F8 gene causes splicing efficiency and premature termination in hemophilia A.

Enzymatically oxidized phospholipids restore thrombin generation in coagulation factor deficiencies.

Management of haemophilia carriers around the time of their delivery: Phenotypic variation requiring customization of management.

Suppressive Role of Tissue Factor Pathway Inhibitor-α in Platelet-Dependent Fibrin Formation under Flow Is Restricted to Low Procoagulant Strength.

Spectrum and origin of mutations in sporadic cases of haemophilia A in China.

Targeting anticoagulant protein S to improve hemostasis in hemophilia.

Evaluation of the self-administered bleeding assessment tool (Self-BAT) in haemophilia carriers and correlations with quality of life.

Improving risk equalization for individuals with persistently high costs: Experiences from the Netherlands.

Direct and indirect gene diagnosis of hemophilia A pedigrees in the Chinese population.

Mice deficient in the anti-haemophilic coagulation factor VIII show increased von Willebrand factor plasma levels.

[EVALUATION OF PARAMETERS OF HEMOSTASIS IN THE THIRD TRIMESTER IN PREGNANT WOMEN WITH CONGENİTAL HEMORRHAGIC DIATHESIS].

[Genetic and prenatal diagnosis for a haemophilia A family with two novel mutations of F8 gene].

Bleeding risk assessment in hemophilia A carriers from Dakar, Senegal.

Comparative study of the prevalence of clotting factor deficiency in carriers of haemophilia A and haemophilia B.

Prenatal genetic testing by late amniocentesis to guide delivery management in haemophilia carriers.

"It was a lot Tougher than I Thought It would be". A Qualitative Study on the Changing Nature of Being a Hemophilia Carrier.

Two rare risk factors for post-partum haemorrhage: a case report of a carrier of severe haemophilia A with a uterine arteriovenous malformation.