Ganglioneuroblastoma

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

NCT06172296

Dual-Target GD2/B7-H3 CAR-NK Cells for Pediatric Relapsed or Refractory Neuroblastoma

Fase II

NCT07502287

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

NCT03126916

Chemoimmunotherapy Combined With Autologous NK Cell Therapy for Pediatric Patients With Refractory and Relapsed High-Risk Neuroblastoma and Ganglioneuroblastoma

NCT07375563

Phase II Study of Proton Radiation Therapy for Neuroblastoma

NCT02112617

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NCT07502287 · Dual-Target GD2/B7-H3 CAR-NK Cells for Pediatric Relapsed or…Recrutando

PHASE1, PHASE2

NCT03126916 · Testing the Addition of 131I-MIBG or Lorlatinib to Intensive…Recrutando

NCT07375563 · Chemoimmunotherapy Combined With Autologous NK Cell Therapy …Recrutando

NCT02112617 · Phase II Study of Proton Radiation Therapy for NeuroblastomaRecrutando

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NCT05192980 · SIOPEN BIOPORTAL, An International Registry Linked to a Virt…Recrutando

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NCT06296732 · Abdominal Neuroblastoma Laparoscopic Surgery Risk Factors St…Recrutando

NCT06071897 · Induction Chemoimmunotherapy for Patients With High-risk Neu…Recrutando

NCT03786783 · Dinutuximab, Sargramostim, and Combination Chemotherapy in T…Ativo

Outros ensaios clínicos

23 ensaios clínicos encontrados, 17 ativos.

Distribuição por fase

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NCT06858501 · Comparing 123I-MIBG and 18F-MFBG Imaging in Patients With Ne…Em breve

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NCT06798532 · Interest of Preoperative Arteriography to Identify the Adamk…Em breve

NCT01175356 · Induction Therapy Including 131 I-MIBG and Chemotherapy in T…Concluído

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NCT03434262 · SJDAWN: St. Jude Children's Research Hospital Phase 1 Study …Concluído

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Publicações mais relevantes

Timeline de publicações

313 papers (10 anos)

#1

[Correlation study between tumor location and pathological subtypes of neuroblastic tumors associated with opsoclonus myoclonus ataxia syndrome].

Zhonghua er ke za zhi = Chinese journal of pediatrics2026 Mar 14

Objective: To analyze the correlation between the location and pathological subtypes of of neuroblastic tumors (NBT) associated with opsoclonus myoclonus ataxia syndrome (OMAS). Methods: A case-control study. Clinical data of 34 pediatric patients diagnosed with NBT complicated by OMAS (NBT-OMAS group), who were hospitalized in the Department of Pediatrics, Peking University First Hospital from January 2007 and December 2022 were collected retrospectively. The control group consisted of 34 age and sex-matched patients with NBT only (NBT-only group) admitted during the same period. Chi-square test or Fisher exact test was used to compare the distribution of tumor locations and pathological subtypes between the two groups. Cramer's V coefficient was applied to analyze the correlation between them. The outcomes of the patients were followed up. Results: The age of patients in the NBT-OMAS group was 18 (12, 28) months, while that of the NBT-only group was 20 (13, 31) months. In the NBT-OMAS group, 28 cases (82%) had tumors located in the paraspinal sympathetic chain and 6 cases (18%) in the adrenal glands. In the NBT-only group, 6 cases (18%) had tumors located in the adrenal glands and 28 cases (82%) in the paraspinal sympathetic chain, with a statistically significant difference between the two groups (χ2=10.69, P<0.01). The distribution of pathological subtypes of tumors in the NBT-OMAS group was as follows: 20 cases (59%) of ganglioneuroblastoma (GNB), 10 cases (29%) of neuroblastoma (NB), 4 cases (12%) of ganglioneuroma (GN). In the NBT-only group, NB was predominant with 21 cases (62%), GNB in 13 cases (38%), and no GN subtype was observed. There was a statistically significant difference between the two groups (χ2=8.59, P<0.01). In the NBT-OMAS group, the pathological subtype of tumors located in the adrenal gland was mainly NB, with 5 cases (5/6). For tumors located paravertebral to the thoracic and lumbar spine, the predominant subtype was GNB, with 8 cases (8/11) and 11 cases (11/13) respectively. As for tumors paravertebral to the sacral spine, the major subtype was NB, with 3 cases (3/4). In the NBT-only group, NB was the pathological subtype in 18 cases of adrenal gland tumors (18/19). For tumors paravertebral to the cervical spine, NB and GNB each accounted for 2 cases respectively (2/4). Tumors located paravertebral to the thoracic spine and paravertebral to the lumbar spine were all GNB for 5 cases (5/5), while those paravertebral to the sacral spine were all NB for 1 case (1/1). The Cramer's V coefficients of the tumor location and pathological subtype in the two groups were 0.65 and 0.81, respectively. The follow-up ended on December 31, 2023. In the NBT-OMAS group, 1 case had tumor recurrence and 1 case died due to tumor progression; both the recurrent and fatal tumors were located in the adrenal glands with the pathological subtype of NB. In the NBT-only group, 11 cases died of tumor progression, among which 8 cases had primary tumor located in the adrenal gland and with the pathological subtype of NB. Conclusions: In children with NBT-OMAS, tumors located in the paravertebral sympathetic chains are significantly more common than those in the adrenal gland, the pathological subtype of tumors was predominantly GNB. The tumor location was correlated with its pathological subtype. 目的：分析并发眼阵挛肌阵挛共济失调综合征（OMAS）的神经母细胞肿瘤（NBT）肿瘤发生部位与病理亚型的相关性。方法：病例对照研究。收集2007年1月至2022年12月在北京大学第一医院儿科住院且明确诊断为NBT并发OMAS的34例患儿（NBT-OMAS组）临床资料，对照组为同期入院、年龄和性别都匹配的单纯NBT患儿34例（单纯NBT组），采用χ2 检验或Fisher确切概率法比较两组肿瘤发生部位、病理亚型的分布情况，通过Cramer′s V系数比较两者的相关性，随访患儿结局。结果： NBT-OMAS组患儿年龄18（12，28）月龄，单纯NBT组年龄为20（13，31）月龄。NBT-OMAS组肿瘤发生于脊柱旁交感神经链者28例（82%）、肾上腺者6例（18%）；单纯NBT组中发生于肾上腺和脊柱旁交感神经链者分别为19例（56%）和15例（44%），两组比较差异有统计学意义（χ2=10.69，P<0.01）。NBT-OMAS组肿瘤病理亚型分布为节细胞神经母细胞瘤（GNB）20例（59%），神经母细胞瘤（NB）10例（29%），节细胞神经瘤（GN）4例（12%）；单纯NBT组病理类型主要为NB 21例（62%），GNB 13例（38%），无GN亚型，两组比较差异有统计学意义（χ2=8.59，P<0.01）。NBT-OMAS组中，6例肿瘤位于肾上腺者中5例为NB；11例位于胸椎旁者中8例为GNB；13例位于腰椎旁者中11例为GNB；4例位于骶椎旁者中3例为NB。单纯NBT组中，19例肿瘤位于肾上腺中18例为NB；4例位于颈椎旁者中NB和GNB各占2例；5例位于胸椎旁和5例位于腰椎旁者均为GNB；1例位于骶椎旁者为NB。两组肿瘤所在部位与其病理亚型的Cramer′s V系数分别为0.65、0.81。随访截至2023年12月31日，NBT-OMAS组1例肿瘤复发、1例因肿瘤进展死亡，肿瘤均位于肾上腺且病理亚型为NB；单纯NBT组有11例因肿瘤进展死亡，其中8例原发肿瘤位于肾上腺且病理亚型为NB。结论： NBT-OMAS患儿肿瘤发生于脊柱旁交感神经链者明显多于肾上腺者；肿瘤病理亚型以GNB者为主；肿瘤发生部位与其病理亚型相关。.

#2

Temporal clustering of neuroblastic tumours in children and young adults from Scotland.

Environmental health : a global access science source2026 Jan 24

Neuroblastic tumours (neuroblastoma and ganglioneuroblastoma) are the most common childhood solid tumours outside the central nervous system, with a median age of diagnosis of 2 years. Temporal clustering of neuroblastic tumours in northern England and Ontario, Canada has been previously reported. We extracted data from the Scottish Cancer Registry to determine whether there was evidence of temporal clustering of neuroblastic tumours. Cases diagnosed in children and young adults aged 0-24 years between 2000 and 2020 were analysed. A modified version of the Potthoff-Whittinghill method was used to test for temporal clustering. Estimates of extra-Poisson variation (EPV) and standard errors (SE) were derived. One hundred and sixty-one cases of neuroblastic tumours, aged 0-24 years, were diagnosed during the study period. Overall, there was statistically significant temporal clustering between years within the full study period (EPV = 9.13, SE = 0.22, P < 0.001). In addition, for cases aged < 18 months, there was significant temporal clustering between months within quarters (EPV = 0.77, SE = 0.41, P = 0.044). For cases aged 18 months - 24 years, there was significant temporal clustering between fortnights within months (EPV = 1.00, SE = 0.47, P = 0.012). The finding of temporal clustering is consistent with the involvement of one or more, as yet unknown, transient environmental agents in the aetiology of neuroblastic tumours.

#3

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma.

Oncology letters2026 May

Telomere maintenance mechanisms (TMM) have garnered attention as a mechanism associated with the treatment resistance and poor prognosis of neuroblastoma (NB). Ganglioneuroblastoma (GNB) and ganglioneuroma (GN) are histologically classified as neuroblastic tumors (NTs) along with NB; however, few reports have addressed TMM in GNB and GN. The present study analyzed 321 NTs diagnosed in Japan, including 255 NB cases, 48 GNB cases and 18 GN cases, using a quantitative PCR-based C-circle assay for alternative lengthening of telomeres (ALT) and a telomerase reverse transcriptase (TERT) mRNA expression assay. ALT was identified in 38 NB cases (38/255, 15%) and 6 GNB cases (6/48, 12.5%), but not in GN. High TERT expression was observed in 38% (64/169), 23% (7/31) and 14% (1/7) of NB, GNB and GN cases, respectively. TMM activation, defined as ALT(+) and/or high TERT expression, occurred in 12/48 GNB cases and 1/18 GN cases, particularly in the GNB-nodular type (10/21, 48%), which was similar to 39% (100/255) of NB cases. Furthermore, TMM(+) GNBs exhibited distinct features, including a high frequency of ATRX alterations and a lower frequency of TERT rearrangements. Chromosomal aberration analysis revealed frequent 7q gain, 17q gain and 11q loss in ALT(+) NTs (83%). Overall, TMM serves as a poor prognostic marker for high-risk NB and offers valuable insights for the risk classification of GNBs.

#4

Can indocyanine green fluorescence aid operative decision making in neuroblastic tumour surgery? Early experience from a single centre.

Journal of pediatric surgery2026 Feb 19

Surgery for neuroblastic tumours can entail difficult decisions about what and where to resect. Indocyanine Green(ICG) near-infrared fluorescence(NIRF) may help with decisions about resecting disease where critical structures are at risk of injury or where a total resection would cause life changing disability. We reviewed the results for all children undergoing ICG NIRF guided surgery for neuroblastic tumours in our centre. Review of single quaternary centre patients between 01/2019 and 12/2023 with a neuroblastic tumour undergoing surgical biopsy or resection with ICG NIRF. Demographics, imaging, tumour details, ICG dosing, intra-operative findings, pathology reports and follow up were reviewed. Twelve patients(6F) underwent 17 surgical procedures (12 resections and 5 biopsies). Six patients were stage L1, four patients L2 and two patients had metastatic disease. Eight patients had neuroblastoma (NBL), 2 ganglioneuroma (GN), and 1 ganglioneuroblastoma (GNBL). One case had mixed biology with multiple foci of NBL and GN. Aflourescence/hypofluorescence occurred in 8 patients with GN, GNBL or <10 % viable NBL. Hyperfluorescence was seen in three patients with primitive neuroblasts confirmed on pathology. In the patient with mixed biology, ICG NIRF showed hyperfluorescent areas (containing primitive neuroblasts) and afluorescent ones (containing GN). Following chemotherapy, all disease was afluorescent. In the fluorescent NBL lesions, NIR microscopy showed a median (IQR) tumour to background ratio (TBR) of 5.385 (4.2):1. The results of this preliminary small cohort suggest that ICG NIRF can predict the presence of primitive neuroblastic tissue and be a useful adjunct to surgical decision making.

#5

The diagnostic value of enhanced CT radiomics and deep learning in differentiating pediatric peripheral neuroblastoma from ganglioneuroblastoma.

BMC cancer2026 Feb 06

To evaluate the diagnostic value of enhanced computed tomography (CT) radiomics and deep learning in differentiating pediatric peripheral neuroblastoma (NB) from ganglioneuroblastoma (GNB). Retrospectively enrolled children with pathologically confirmed NB and GNB between February 2014 and December 2024 were randomly sampled and divided into a training set and a validation set. Radiomic features were extracted and selected from arterial-phase and venous-phase CT images. A 3D-UNet model was constructed to train a lesion segmentation model. Radiomic features were automatically extracted and selected from CT images using the 3D-UNet model. Radiomics models and combined models (incorporating clinical indicators) were established on the basis of the optimal feature subsets for the arterial phase, venous phase, arteriovenous phase, and combined clinical data. Receiver operating characteristic (ROC) curves were plotted, and the area under the curve (AUC) was calculated and compared across phases and models. A total of 225 pediatric patients (161 NB cases and 64 GNB cases) were enrolled. Compared with the radiomic-only models (LDA and LR), the combined models (LDA and LR) incorporating radiomic and clinical features (age and NSE) demonstrated greater diagnostic performance in differentiating NB and GNB. The 3D-UNet-based deep learning model achieved optimal performance after 20 training iterations, with a best Dice coefficient of 0.818 for mixed tumor types in the validation set.The optimal diagnostic performance was achieved by the LR combined model based on venous-phase CT images’ omics features and clinical data (CE2 + C), with an AUC of 0.922 in the training set and 0.913 in the validation set. Both the LDA and LR models exhibited high diagnostic efficacy, with no statistically significant difference (P > 0.05) between the models. There was also no significant difference (P > 0.05) in the diagnostic performance of the combined models across phases when incorporating clinical information. Enhanced CT radiomics and deep learning models have significant diagnostic value in differentiating pediatric peripheral NB from GNB.

Publicações recentes

Infantile Ganglioneuroblastoma Causing Growth Failure and Hypertensive Cardiomyopathy From Excessive Catecholamine Production.

J Pediatr Hematol Oncol2026 Mar 20

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma.

Oncol Lett2026 May

[Correlation study between tumor location and pathological subtypes of neuroblastic tumors associated with opsoclonus myoclonus ataxia syndrome].

Zhonghua Er Ke Za Zhi2026 Mar 14

Can indocyanine green fluorescence aid operative decision making in neuroblastic tumour surgery? Early experience from a single centre.

J Pediatr Surg2026 Feb 19

The diagnostic value of enhanced CT radiomics and deep learning in differentiating pediatric peripheral neuroblastoma from ganglioneuroblastoma.

BMC Cancer2026 Feb 6

Ver todas no PubMed

📚 EuropePMC387 artigos no totalmostrando 198

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma.

Zhonghua er ke za zhi = Chinese journal of pediatrics

[Correlation study between tumor location and pathological subtypes of neuroblastic tumors associated with opsoclonus myoclonus ataxia syndrome].

Journal of pediatric surgery

Can indocyanine green fluorescence aid operative decision making in neuroblastic tumour surgery? Early experience from a single centre.

The diagnostic value of enhanced CT radiomics and deep learning in differentiating pediatric peripheral neuroblastoma from ganglioneuroblastoma.

BMC cancer

Pathology of peripheral neuroblastic tumors.

Diagnostic pathology

Frontiers in endocrinology

Simultaneous occurrence of bilateral retroperitoneal neuroblastoma and bifocal malignant mixed germ cell tumor in a pediatric patient with 16p11.2 microdeletion syndrome: a case report.

Environmental health : a global access science source

Temporal clustering of neuroblastic tumours in children and young adults from Scotland.

Is There a Role for Chemotherapy in Unresectable Ganglioneuroblastoma Intermixed?: A Case Series Analysis.

Cancer research communications

Copy-Number Aberrations in Circulating Tumor DNA Enable Diagnosis and Risk Stratification of Pediatric Neuroblastic Tumors.

Zhonghua bing li xue za zhi = Chinese journal of pathology

[Clinicopathological and molecular genetic features of pediatric malignant peripheral nerve sheath tumors originating from ganglioneuroma/ganglioneuroblastoma].

Histologic Response to Induction Chemotherapy in High-Risk Neuroblastoma.

Cancer medicine

Journal of Indian Association of Pediatric Surgeons

Uncommon Location for Pelvic Ganglioneuroblastoma: Pelvic Nebenorgane.

Journal of neuro-oncology

Peripheral neural crest tumor brain metastases management: a single-institution retrospective study.

Therapy-Related Acute Myeloid Leukemia with inv(16) in a Child after Chemotherapy for Previous Ganglioneuroblastoma.

Clinical laboratory

European journal of medical genetics

Clinical and molecular findings of KMT2D-related Kabuki syndrome: A series of 13 patients with 3 novel variants.

Pathological validation of 18F-AlF-NOTA-octreotide PET/CT for neuroblastoma.

Scientific reports

British journal of haematology

Ganglioneuroblastoma with cannibalism in bone marrow.

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics

[Beckwith-Wiedemann syndrome with ganglioneuroblastoma: a case report].

Predictive value of multiparametric diagnostic model based on 2-[18F]-fluoro-D-glucose (2-[18F]-FDG) positron emission tomography/computed tomography (PET/CT) metabolic parameters in differentiating between neuroblastoma and ganglioneuroblastoma.

Clinical radiology

European journal of nuclear medicine and molecular imaging

A head-to-head prospective comparative analysis of 68Ga-DOTATATE PET/CT and 123I-MIBG SPECT/CT in central nervous system metastases of neuroblastoma and ganglioneuroblastoma.

SNP array analysis facilitates the identification of novel chromosomal alterations associated with disease and SNPs related to adverse drug reactions in neuroblastoma.

Surgical pathology clinics

Diagnostic Challenges and Updates in Peripheral Neuroblastic Tumors.

Journal of Indian Association of Pediatric Surgeons

Transperitoneal Laparoscopic Adrenalectomy in Children - Initial Experience in an Emerging Tertiary Center in Eastern India.

Tertiary Lymphoid Structures Are Associated with Progression-Free Survival of Peripheral Neuroblastic Tumor Patients.

Cancers

Rubinstein-Taybi syndrome with ganglioneuroblastoma: a case report and literature review.

BMC pediatrics

Confusing Onset of MOGAD in the Form of Focal Seizures.

Neurology international

Journal of neurosurgery. Case lessons

Stereotactic radiosurgery for brain metastases secondary to adrenal ganglioneuroblastoma: illustrative case.

Radiomics analysis based on 18F-fluorodeoxyglucose positron emission tomography/computed tomography for differentiating the histological classification of peripheral neuroblastic tumours.

Clinical radiology

Clinical nuclear medicine

Positive 18 F-FDG PET/CT and Negative 123 I-MIBG SPECT/CT Imaging in an Unusual Diaphragmatic Metastasis From Ganglioneuroblastoma.

Journal of translational medicine

Proteomic analysis reveals chromatin remodeling as a potential therapeutical target in neuroblastoma.

The Journal of surgical research

A Single-Institution Analysis of Surveillance Practice for Low-Risk Neuroblastic Tumors.

Journal of surgical oncology

Adults and Adolescents With Neuroblastoma: An Analysis of the National Cancer Database.

International cancer conference journal

Intraventricular ganglioneuroblastoma: an uncommon location for a rare tumour in a young adult with review of literature.

Current pediatric reviews

Primary Renal Neuroblastoma: A Case Report and Review of the Literature.

Journal of clinical medicine

Characterisation of Paediatric Neuroblastic Tumours by Quantitative Structural and Diffusion-Weighted MRI.

Management of Ganglioneuroma and Ganglioneuroblastoma Intermixed: A United Kingdom Children's Cancer and Leukaemia Group (UK CCLG) Nationwide Study Report.

Unraveling the glycosphingolipid metabolism by leveraging transcriptome-weighted network analysis on neuroblastic tumors.

Cancer & metabolism

Vasoactive Intestinal Peptide-Producing Neuroblastic Tumors: A Rare Cause of Refractory Diarrhea.

Cureus

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Primary intracranial pediatric ganglioneuroblastoma-report of two cases and review of an unusual masquerader.

The Journal of veterinary medical science

A case of olfactory ganglioneuroblastoma in a dog: immunohistochemical comparison with olfactory neuroepithelia and olfactory neuroblastomas.

Pediatrics international : official journal of the Japan Pediatric Society

Successful endoscopic approach for peripheral neuroblastic tumors in children.

Indocyanine green fluorescence imaging-assisted laparoscopy resection of retroperitoneal tumors in children: case report and literature review.

Abdominal radiology (New York)

A head-to-head comparison of computed tomography- and magnetic resonance imaging-based radiomics in assessing pediatric peripheral neuroblastic tumor cell behavior.

Adolescent- and adult-onset neuroblastic tumor: A retrospective multicenter observational study of patients diagnosed in France between 2000 and 2020.

Development and validation of a prognostic nomogram for patients with ganglioneuroblastoma: A SEER-based study.

Heliyon

Anti-Hu antibody associated paraneoplastic neurological syndrome in a child with ganglioneuroblastoma: A rare case report and literature review.

Medicine

Ultrasound in medicine & biology

A Preliminary Study on the Application of Contrast-Enhanced Ultrasonography in Children With Peripheral Neuroblastic Tumors.

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc

Review of neoplasia in fish at a large display aquarium, 2005-2021.

Clinical features and treatment options for pediatric adrenal incidentalomas: a retrospective single center study.

BMC pediatrics

Adrenal ganglioneuroblastoma with metastasis near the renal hilum in an adult female: A case report and review of the literature.

International journal of molecular sciences

High-Titer Anti-ZSCAN1 Antibodies in a Toddler Clinically Diagnosed with Apparent Rapid-Onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation Syndrome.

Benign paraspinal ganglioneuroma with paraneoplastic opsoclonus myoclonus syndrome.

BMJ case reports

Clinical nuclear medicine

Coexistence of Langerhans Cell Histiocytosis and Ganglioneuroblastoma Revealed by 18 F-FDG PET/CT in a Pediatric Patient.

Archives of environmental & occupational health

A geospatial assessment of industrial releases and pediatric neuroblastic tumours at diagnosis: A retrospective case series.

British journal of neurosurgery

Intracranial leptomeningeal CNS ganglioneuroblastoma. First report and review of the literature.

A needle in the haystack: An unusual case presentation of ganglioneuroblastoma at a tertiary care center in Coastal Karnataka.

Clinical case reports

N6-methyladenosine-mediated overexpression of long noncoding RNA ADAMTS9-AS2 triggers neuroblastoma differentiation via regulating LIN28B/let-7/MYCN signaling.

JCI insight

Current pediatric reviews

Late Relapse in Neuroblastoma: Case Report and Review of the Literature.

Life (Basel, Switzerland)

Chronic Diarrhea Caused by Vasoactive Intestinal Peptide-Secreting Tumor.

Norepinephrine transporter and vesicular monoamine transporter 2 tumor expression as a predictor of response to 131 I-MIBG in patients with relapsed/refractory neuroblastoma.

Journal of laparoendoscopic & advanced surgical techniques. Part A

Laparoscopic Transperitoneal Adrenalectomy for Adrenal Tumors in Children: Technical Considerations and Surgical Experience.

Medical oncology (Northwood, London, England)

Musashi-2 (MSI2) promotes neuroblastoma tumorigenesis through targeting MYC-mediated glucose-6-phosphate dehydrogenase (G6PD) transcriptional activation.

Pathologie (Heidelberg, Germany)

[Peripheral neuroblastic tumors in childhood].

Contemporary oncology (Poznan, Poland)

Great mimicker - a case of occult melanoma displaying ganglioneuroblastic differentiation.

Single-cell transcriptome sequencing reveals tumor heterogeneity in family neuroblastoma.

Frontiers in immunology

Computer-assisted resection of multifocal primary neuroblastic tumors: A case report.

Asian journal of surgery

Journal of clinical medicine

Nonspecific Gastrointestinal Symptoms as the First Sign of Ganglioneuroblastoma Intermixed-Case Report and Literature Review.

Annals of surgical treatment and research

The prognostic and predictive value of plasma D-dimer in children with neuroblastoma: a 7-year retrospective analysis at a single institution.

Journal of neuropathology and experimental neurology

Maturation of metastases in peripheral neuroblastic tumors (neuroblastoma) of children.

The journal of pathology. Clinical research

Translational practice of fluorescence in situ hybridisation to identify neuroblastic tumours with TERT rearrangements.

Journal of nuclear medicine technology

Cervical Ganglioneuroblastoma Diagnosed by 68Ga-DOTATOC PET/CT in a Child with Opsoclonus Myoclonus Syndrome.

American journal of translational research

Clinicopathological significance of vasculogenic mimicry and fetal hemoglobin expression in peripheral neuroblastic tumors in children.

Advances in experimental medicine and biology

Brain and Spinal Cord Tumors of Embryonic Origin.

Advances in experimental medicine and biology

Embryonal Tumors of the Central Nervous System with Multilayered Rosettes and Atypical Teratoid/Rhabdoid Tumors.

Abdominal radiology (New York)

Correlations between contrast-enhanced CT-measured extracellular volume fraction, histopathological features, and MYCN amplification status in abdominal neuroblastoma: a retrospective study.

World journal of gastrointestinal surgery

Computer-assisted rescue of the inferior mesenteric artery in a child with a giant ganglioneuroblastoma: A case report.

International journal of surgical pathology

Gastric Ganglioneuroblastoma in an Elderly man: A Case Report and Literature Review.

Ganglioneuroblastoma intermixed: Clinicopathological implications of diagnosis at presentation and genomic correlations.

Identification and validation of radiomic features from computed tomography for preoperative classification of neuroblastic tumors in children.

BMC pediatrics

Outcomes and Histological Variations of Neuroblastoma and Ganglioneuroblastoma with Paraneoplastic Syndromes.

The American surgeon

Journal of neuropathology and experimental neurology

An infantile pineal embryonal tumor showing pathological features of a CNS ganglioneuroblastoma and the methylation profiling of an atypical teratoid/rhabdoid tumor and SMARCA4 mutation.

Indian journal of pathology & microbiology

Extra-adrenal peripheral neuroblastic tumors: A clinicopathological study of 18 cases.

Clinical value of 18F-FDG PET/CT to predict MYCN gene, chromosome 1p36 and 11q status in pediatric neuroblastoma and ganglioneuroblastoma.

Frontiers in oncology

Five Years Follow-up of Opsoclonus-Myoclonus-Ataxia Syndrome-Associated Neurogenic Tumors in Children.

Neuropediatrics

A male with ganglioneuroblastoma cerebrospinal hemorrhages, cardiomyopathy, and retinopathy due to severe hypertension.

Abdominal radiology (New York)

Whole-tumor radiomics analysis of T2-weighted imaging in differentiating neuroblastoma from ganglioneuroblastoma/ganglioneuroma in children: an exploratory study.

Saudi journal of biological sciences

Pathological and clinical outcomes of adrenalectomy: A multi-center experience in Saudi Arabia.

JPMA. The Journal of the Pakistan Medical Association

Paediatric metastatic ganglioneuroblastoma on 68Ga-DOTA NOC PET-CT.

Adrenal Ganglioneuroblastoma of Adult Onset: A Literature Review.

Cureus

Seminars in roentgenology

ANNA-1-associated paraneoplastic limbic encephalitis in a patient with pelvic ganglioneuroblastoma.

The Journal of craniofacial surgery

Ganglioneuroblastoma Presenting as Obstructive Sleep Apnea in a 5-Year-Old Boy.

Comparing the diagnostic value of 18F-FDG PET/CT scan and bone marrow biopsy in newly diagnosed pediatric neuroblastoma and ganglioneuroblastoma.

Frontiers in oncology

Mediastinum (Hong Kong, China)

Giant tumors of the posterior mediastinum: a narrative review of surgical treatment.

Diagnostics (Basel, Switzerland)

The Pitfall of Ganglioneuroblastoma-Nodular Diagnosis: Clinical and Imaging Considerations over a Rare Bifocal Sporadic Case.

Cellular oncology (Dordrecht, Netherlands)

Targeting ARHGEF12 promotes neuroblastoma differentiation, MYCN degradation, and reduces tumorigenicity.

Turkish journal of anaesthesiology and reanimation

Rapid-Onset Obesity, Hypothalamic Dysregulation, Hypoventilation, Autonomic Dysregulation, and Neuroendocrine Tumour: Rare Syndrome with Myriad Anaesthesia Implications.

Neuroblastic tumors and neurofibromatosis type 1: A retrospective multicenter study in Italy and systematic review of the literature.

Blueberry muffin baby secondary to ganglioneuroblastoma.

Pediatric dermatology

Gynecologic oncology reports

Ganglioneuroblastoma arising in a Mature Cystic Teratoma of Ovary: Report and Literature review of an uncommon neoplasm.

Translational cancer research

Comparison of mediastinal and non-mediastinal neuroblastoma and ganglioneuroblastoma associated with opsoclonus-myoclonus syndrome: a systematic review and meta-analysis.

Composite pheochromocytoma-ganglioneuroma: a case with two distinct components radiographically.

BJR case reports

Methods in molecular biology (Clifton, N.J.)

Determination of Catecholamines in a Small Volume (25 μL) of Plasma from Conscious Mouse Tail Vein.

Single-cell profiling of peripheral neuroblastic tumors identifies an aggressive transitional state that bridges an adrenergic-mesenchymal trajectory.

Cell reports

Relationship between the timing of chemotherapy and surgical complications following surgical biopsy in children with malignant solid tumors.

Frontiers in endocrinology

Long-term survival outcomes of pediatric adrenal malignancies: An analysis with the upstaged SEER registry during 2000-2019.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society

Clinical features and outcomes of opsoclonus myoclonus ataxia syndrome.

Early-phase clinical trial eligibility and response evaluation criteria for refractory, relapsed, or progressive neuroblastoma: A consensus statement from the National Cancer Institute Clinical Trials Planning Meeting.

Cancer

Handbook of clinical neurology

Developmental disorders affecting the respiratory system: CCHS and ROHHAD.

Computers in biology and medicine

Pathological prognosis classification of patients with neuroblastoma using computational pathology analysis.

Journal of pediatric surgery

Clinical and surgical outcome differences on the basis of pathology category in cervical neuroblastic tumors.

Journal of Indian Association of Pediatric Surgeons

Management of Primary Thoracic Neuroblastic Tumors in Children: An Observational Study.

Early and Aggressive Treatment May Modify Anti-Hu Associated Encephalitis Prognosis.

Neuropediatrics

Retroperitoneal ganglioneuroblastoma with postoperative stress ulcer perforation in an adolescent: A case report and review of the literature.

International journal of surgical pathology

A Rare Case of a Solitary Fibrous Tumor in a Child, Presenting as a Congenital Mass, Displaying NAB2ex4::STAT6ex2 Gene Fusion with an Incidental Ganglioneuroblastoma.

Neuroblastic Tumors of the Adrenal Gland in Elderly Patients: A Case Report and Review of the Literature.

Fetal and pediatric pathology

Ewing Sarcoma Displaying Extensive Well Differentiated Neuroblastomatous Differentiation: A Case Report.

Ear, nose, & throat journal

Ganglioneuroblastoma in the Retropharyngeal Space: A Case Report and Literature Review.

Iranian journal of child neurology

Primary Spinal Tumors and Masses in Children.

Ganglioneuroblastoma in a Child With Neurofibromatosis Type 1: A Case Report and Literature Review.

Ganglion cell maturation in peripheral neuroblastic tumours of children.

Clinical neuropathology

Robotics-Assisted Pediatric Oncology Surgery-A Preliminary Single-Center Report and a Systematic Review of Published Studies.

Exploring the prognosis of neuroblastoma in adolescents and adults: a case series and literature review.

Neoplasma

Genetic and Histopathological Heterogeneity of Neuroblastoma and Precision Therapeutic Approaches for Extremely Unfavorable Histology Subgroups.

Biomolecules

Radiation oncology (London, England)

Risk of developing second malignant neoplasms in patients with neuroblastoma: a population study of the US SEER database.

Nan fang yi ke da xue xue bao = Journal of Southern Medical University

[Computed tomography-based radiomics for differential of retroperitoneal neuroblastoma and ganglioneuroblastoma in children].

Clinical Analysis of Pediatric Opsoclonus-Myoclonus Syndrome in One of the National Children's Medical Center in China.

Frontiers in neurology

Anatomic patterns of relapse and progression following treatment with 131 I-MIBG in relapsed or refractory neuroblastoma.

Experimental and therapeutic medicine

Adrenal ganglioneuroma: Prognostic factors (Review).

Revista espanola de medicina nuclear e imagen molecular

Unique case of adult onset posterior mediastinal ganglioneuroblastoma on 68Ga DOTATATE PET/CT.

Surgery journal (New York, N.Y.)

Duodenal Ganglioneuroma: A Rare Tumor Causing Upper Gastrointestinal Bleed.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Minimally invasive surgery for neuroblastic tumours: A SIOPEN multicentre study: Proposal for guidelines.

Annals of clinical and laboratory science

Composite Neuroblastoma Metastatic to a Lymph Node: The Novel Histopathologic Diagnosis of a Unique Multiclonal Neoplasm.

Annals of surgical treatment and research

Adrenal ganglioneuroma resected for suspicious malignancy: multicenter review of 25 cases and review of the literature.

Indian journal of pathology & microbiology

Composite phaeochromocytoma with malignant peripheral nerve sheath tumour: A case report with summary of prior published cases.

Annals of surgical oncology

The Relevance of Preoperative Identification of the Adamkiewicz Artery in Posterior Mediastinal Pediatric Tumors.

Open medicine (Warsaw, Poland)

Primary orbital ganglioneuroblastoma: A case report.

A rare case of adrenal ganglioneuroblastoma-intermixed in an adult and a review of literature.

Radiology case reports

Unresectable thoracic neuroblastic tumors: Changes in image-defined risk factors after chemotherapy and impact on surgical management.

Journal of pediatric surgery

Characteristics of benign neuroblastic tumors: Is surgery always necessary?

Seminars in diagnostic pathology

Mediastinal neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: Pathology review and diagnostic approach.

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc

Olfactory ganglioneuroblastoma in a dog: case report and literature review.

A Metastatic Neuroblastic Tumor in a 28-Month-old Boy: Unusual Spontaneous Regression From Neuroblastoma to Ganglioneuroma?

Pediatrics international : official journal of the Japan Pediatric Society

Coexistence of orbital rhabdomyosarcoma and adrenal neuroblastic tumor in a child.

International journal of environmental research and public health

Metastatic Neuroblastoma Presenting as a Submandibular Mass with Mandibular Bone Involvement in a Three-Year-Old Child.

Refractory Stage M Ganglioneuroblastoma With Bone Metastases and a Favorable, Chronic Course of Disease: Description of a Patient Cohort.

Primary cervical ganglioneuroblastoma, nodular subtype.

Auris, nasus, larynx

Clinical and Pathological Evidence of Anti-GD2 Immunotherapy Induced Differentiation in Relapsed/Refractory High-Risk Neuroblastoma.

Cancers

Langenbeck's archives of surgery

Composite phaeochromocytomas-a systematic review of published literature.

Virchows Archiv : an international journal of pathology

Primary uterine ectomesenchymoma harboring a DICER1 mutation: case report with molecular analysis.

Expression of BARD1 β Isoform in Selected Pediatric Tumors.

Genes

Pediatrics international : official journal of the Japan Pediatric Society

Primary renal ganglioneuroblastoma mimicking Wilms' tumor in a 3-year-old girl.

Diagnostic values of 68Ga-labelled DOTANOC PET/CT imaging in pediatric patients presenting with paraneoplastic opsoclonus myoclonus ataxia syndrome.

European radiology

Cancer imaging : the official publication of the International Cancer Imaging Society

Feasibility and possible value of quantitative semi-automated diffusion weighted imaging volumetry of neuroblastic tumors.

A Rare Cause of Sleep-Disordered Breathing: ROHHAD Syndrome.

Association of image-defined risk factors with clinical features, histopathology, and outcomes in neuroblastoma.

Cancer medicine

Medical science monitor : international medical journal of experimental and clinical research

Comparison of Incidence and Outcomes of Neuroblastoma in Children, Adolescents, and Adults in the United States: A Surveillance, Epidemiology, and End Results (SEER) Program Population Study.

Surgical pathology clinics

New Prognostic Indicators in Pediatric Adrenal Tumors: Neuroblastoma and Adrenal Cortical Tumors, Can We Predict When These Will Behave Badly?

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Incidence of Horner syndrome associated with neuroblastic disease.

Genomic profile of MYCN non-amplified neuroblastoma and potential for immunotherapeutic strategies in neuroblastoma.

BMC medical genomics

Primary orbital ganglioneuroblastoma in a child: A case report.

Medicine

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Harlequin syndrome associated with ganglioneuroblastoma-induced Horner syndrome.

Robotic adrenalectomy in the pediatric population: initial experience case series from a tertiary center.

BMC urology

Brain paraneoplastic syndromes in a patient with mediastinal ganglioneuroma.

Radiology case reports

Science China. Life sciences

MYC-associated protein X binding with the variant rs72780850 in RNA helicase DEAD box 1 for susceptibility to neuroblastoma.

Retrospective accuracy analysis of MRI based lesion size measurement in neuroblastic tumors: which sequence should we choose?

BMC medical imaging

Diagnostics (Basel, Switzerland)

Diagnostic Use of Post-therapy 131I-Meta-Iodobenzylguanidine Scintigraphy in Consolidation Therapy for Children with High-Risk Neuroblastoma.

Annals of nuclear medicine

High-dose 131I-mIBG as consolidation therapy in pediatric patients with relapsed neuroblastoma and ganglioneuroblastoma: the Japanese experience.

Rare Cases of Pediatric Vasoactive Intestinal Peptide Secreting Tumor With Literature Review: A Challenging Etiology of Chronic Diarrhea.

Primary round cell sarcomas of the urinary bladder with EWSR1 rearrangement: a multi-institutional study of thirteen cases with a review of the literature.

Human pathology

Retroperitoneal Ganglioneuroma in a Patient Presenting With Vague Abdominal Pain.

Cureus

The Journal of experimental medicine

Ganglioneuromas are driven by activated AKT and can be therapeutically targeted with mTOR inhibitors.

Adult-onset ganglioneuroblastoma of the posterior mediastinum with osseous metastasis.

Radiology case reports

Central nervous system ganglioneuroblastoma harboring MYO5A-NTRK3 fusion.

Brain tumor pathology

Frontiers in endocrinology

A Novel MAX Gene Mutation Variant in a Patient With Multiple and "Composite" Neuroendocrine-Neuroblastic Tumors.

Seminars in diagnostic pathology

Neurogenic Tumors of the Mediastinum.

The Journal of clinical endocrinology and metabolism

ROHHAD(NET) Syndrome: Systematic Review of the Clinical Timeline and Recommendations for Diagnosis and Prognosis.

Surgical pathology clinics

Embryonal Tumors of the Central Nervous System: An Update.

Incidence, Treatment, and Survival in Primary Central Nervous System Neuroblastoma.

World neurosurgery

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Suprasellar central nervous system ganglioneuroblastoma: a case in a 9-year-old child and review of the literature.

Journal of paediatrics and child health

Incidence and outcomes of neuroblastoma in Australian children: A population-based study (1983-2015).

Pediatric neuroblastic tumors: A critical evaluation of cytomorphological features for risk stratification on aspiration cytology.

Diagnostic cytopathology

American journal of medical genetics. Part A

Tatton-Brown-Rahman syndrome: Six individuals with novel features.

The journal of pathology. Clinical research

Biomarker recommendation for PD-1/PD-L1 immunotherapy development in pediatric cancer based on digital image analysis of PD-L1 and immune cells.

Therapeutic results in three cases of ganglioneuroblastoma associated with opsoclonus myoclonus ataxia syndrome.

Indian journal of cancer

Posterior mediastinal ganglioneuroblastoma in an adolescent: A case report and review.

Thoracic cancer

Importance of Magnetic Resonance Imaging With Diffusion-weighted Imaging in Guiding Biopsy of Nodular Ganglioneuroblastoma: A Case Report.

Journal of pediatric surgery case reports

Resection of a thoracoabdominal ganglioneuroma via a retroperitoneal minimally invasive approach.

Mathematical biosciences and engineering : MBE

Exome sequencing identifies predisposing and fusion gene in ganglioneuroma, ganglioneuroblastoma and neuroblastoma.

European journal of pediatric surgery reports

Minimally Invasive Surgery for Pediatric Adrenal Masses-Report on Four Cases.

The ganglioside GD2 as a circulating tumor biomarker for neuroblastoma.

Asian cardiovascular & thoracic annals

A single-institution experience of neurogenic tumors of the mediastinum.

β2‑adrenergic receptor signaling promotes neuroblastoma cell proliferation by activating autophagy.

Oncology reports

Journal of experimental & clinical cancer research : CR

FUBP1 promotes neuroblastoma proliferation via enhancing glycolysis-a new possible marker of malignancy for neuroblastoma.

Diagnostic value of whole-body MRI in Opsoclonus-myoclonus syndrome: a clinical case series (3 case reports).

BMC medical imaging

International journal of surgery case reports

Case report of severe psychiatric sequelae in a 16-year-old female following resection of a purely dopamine-secreting ganglioneuroma.

Results of a prospective clinical trial JN-L-10 using image-defined risk factors to inform surgical decisions for children with low-risk neuroblastoma disease: A report from the Japan Children's Cancer Group Neuroblastoma Committee.

Congenital malformation syndromes associated with peripheral neuroblastic tumors: A systematic review.