Introdução
O que você precisa saber de cara
Defeitos do tubo neural (DTNs) são um grupo de defeitos congênitos nos quais uma abertura na coluna vertebral ou no crânio permanece desde o início do desenvolvimento humano. Na terceira semana de gravidez, chamada gastrulação, células especializadas na parte dorsal do embrião começam a mudar de forma e a formar o tubo neural. Quando o tubo neural não se fecha completamente, um DTN se desenvolve.
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Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Linha do tempo da pesquisa
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Genética e causas
O que está alterado no DNA e como passa nas famílias
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Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Lipomielomeningocele
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Publicações mais relevantes
Sacral dimple: clinical perspectives of lesions hidden beneath the skin.
Sacral dimples are the most common cutaneous anomalies in newborns. While usually benign anatomical variants, some dimples are indicative of occult spinal dysraphism, such as a tethered cord, dermal sinus tract, or lipomyelomeningocele, that, if undiagnosed, may cause irreversible neurological, orthopedic, and urological deficits. Distinguishing benign from high-risk dimples is essential for timely intervention. This review summarizes the embryological origins, diagnostic criteria, imaging approaches, and management strategies for sacral dimples to help clinicians identify cases requiring further evaluation. A comprehensive literature review examines the embryology of caudal spinal development, classification of spinal dysraphism, and studies of the diagnostic accuracy of ultrasonography and magnetic resonance imaging (MRI) in infants with sacral dimples. Guidelines and high-quality studies of the surgical outcomes of tethered cords and related anomalies were also analyzed. The literature search and study selection followed the Preferred Reporting Items for Systematic Reviews and Meta- Analyses flow. Simple sacral dimples-solitary midline depressions less than 5 mm in diameter, located within 2.5 cm of the anus, and lacking associated cutaneous stigmata-are not associated with spinal dysraphism and do not require imaging. In contrast, atypical dimples (large, deep, off-midline, or associated with skin markers such as hair tufts or hemangiomas) are significantly associated with occult anomalies and warrant imaging, beginning with spinal ultrasonography in neonates and MRI in older infants or equivocal cases. Conditions such as tethered cord, dermal sinus tract, lipomyelomeningocele, and split cord malformations are best visualized using MRI. Early surgical detethering improves neurological, orthopedic, and bladder outcomes, whereas delayed intervention risks permanent deficits. Applying standardized criteria and targeted imaging avoids unnecessary investigations while ensuring a timely diagnosis of occult spinal dysraphism. Early recognition and appropriate surgical management, when indicated, are critical for preventing neurological deterioration and improving the prognosis of affected infants.
Tethered Cord Syndrome in Pediatric and Adult Populations: A Retrospective Analysis of Outcomes and Associated Spinal Dysraphisms.
Background and objective Tethered cord syndrome (TCS) is an amalgam of neurologic, urologic, orthopedic, and dermatologic dysfunctions with concurrent spinal dysraphism and deformities. Data from Pakistan regarding the surgical management of TCS remain limited. This study aimed to evaluate the clinical and functional outcomes of surgical detethering in patients with TCS and spinal dysraphism. Materials and methods This retrospective study was conducted at the Punjab Institute of Neurosciences (PINS), Lahore, Pakistan. We analyzed the outcomes of 21 patients (12 pediatric and nine adults) with TCS who were operated on between January 2020 and June 2025. Patient records were reviewed using the institution's Picture Archiving and Communication System (PACS), operative notes, and medical charts. Results of the treatment were summarized and analyzed using descriptive statistical analysis. Results Among the cohort, 12 patients were pediatric and nine were adults. Pediatric patients had an average age of 4.95 ± 5.03 years and showed a female predominance (66.66%, n = 8). Adults had a mean age of 23.44 ± 8.84 years and also demonstrated a female predominance (66.66%, n = 6). Lower limb weakness was the most frequent presenting symptom, occurring in 50% (n = 6) of children and in a higher proportion of adults at 66.66% (n = 6). Lipomyelomeningocele was the most frequently observed form of spinal dysraphism in children, accounting for 33.33% (n = 4), whereas thickened filum terminale was most common in adults, seen in 33.33% (n = 3). The conus level was most commonly located at L1 in pediatric patients, observed in 50.00% (n = 6), while in adults it was most frequently at L3, occurring in 55.55% (n = 5). Detethering of the spinal cord was the predominant surgical intervention in both pediatric and adult groups, performed in 91.66% (n = 11) of children and 100% (n = 9) of adults. Postoperative assessment showed neurological improvement in 75% (n = 9) of pediatric patients and 55.55% (n = 5) of adults, with no major complications reported in 91.66% (n = 11) of children and 66.66% (n = 6) of adults. Conclusions Surgical untethering in patients with TCS leads to improvement in neurological function with an acceptable safety profile, highlighting the importance of early intervention.
Mediating Effects of Family and Clinical Characteristics on the Quality of Life of Children With Spina Bifida and Their Parents.
(1) To determine the mediating effects of children's transition readiness, which reflects self-management skill acquisition, and family resilience on the relationship between parenting stress and the quality of life (QOL) of parents and children with spina bifida (SB). (2) To conduct an exploratory analysis of the differences in the mediating pathways based on the presence of SB-related clinical characteristics. A cross-sectional study. Data were collected from a single centre in South Korea between October 2022 and July 2024. Participants included children aged 7-13 years diagnosed with myelomeningocele, lipomyelomeningocele or tethered cord syndrome, along with their parents. Statistical analysis was conducted using SPSS and the MEDYAD macro for actor-partner interdependence mediation model analysis. Family resilience significantly mediated the relationship between parenting stress and both child and parent QOL. However, transition readiness was not a significant mediator in the overall sample. Among children with SB-related clinical characteristics, transition readiness significantly mediated the association between parenting stress and child QOL. In contrast, family resilience mediated the relationship between parenting stress and parent QOL. No significant mediators were found in children without SB-related clinical characteristics. This study highlights the mediating role of family resilience and transition readiness in improving the QOL of children with SB, particularly those with clinical characteristics. The findings suggest that interventions should be tailored to address both family resilience and transition readiness, especially for children with SB-related clinical challenges. These findings are valuable for nurses supporting children with SB, as the results highlight the importance of transition education tailored to SB-related clinical characteristics. In particular, nurse-led transition education may play a key role in enhancing transition readiness and improving the QOL of children with SB who have clinical characteristics. None. STROBE Checklist for cross-sectional studies. Spina bifida is a congenital anomaly resulting from incomplete neural tube development (see Image. Infant With Spina Bifida). The term "spina bifida" is nonspecific and refers to any degree of neural tube closure defect. This condition can be divided into 2 categories—spina bifida occulta and spina bifida aperta. Spina bifida occulta, also known as closed spinal dysraphism, is the mildest form of neural tube defect (NTD), characterized by a concealed vertebral defect with minimal neural involvement. Spina bifida aperta, also known as open spinal dysraphism, refers to a defect in which neural tissue is exposed and communicates with the external environment, such as in meningocele, myelomeningocele, and myeloschisis (see Image. Types of Spina Bifida). These conditions result in a wide range of neurological impairments. Spina bifida is often associated with several other developmental abnormalities, highlighting the importance of an interprofessional medical approach to optimize patient survival and outcomes. Atypical variants of spinal bifida include segmental spinal dysgenesis, lipomyelomeningocele, human tail, membranous meningocele, and myeloschisis. These variants are associated with autonomic dysfunction, kyphotic deformity, and lower limb anomalies.
Double jeopardy in early infancy: aperta lipomyelomeningocele with Chiari II malformation complicated by infantile hypertrophic pyloric stenosis.
Aperta lipomyelomeningocele (LMMC) is a form of open spinal dysraphism often associated with Chiari II malformation. Infantile hypertrophic pyloric stenosis (IHPS), the leading surgical cause of gastric-outlet obstruction in early infancy, has rarely been reported alongside LMMC and Chiari II. We present a term male neonate who underwent early repair of lumbosacral LMMC and later ventriculo-peritoneal (VP) shunting for post-haemorrhagic hydrocephalus. Persistent non-bilious vomiting despite functional shunting led to imaging that confirmed IHPS. The infant required a phased surgical approach, combining Ramstedt pyloromyotomy with simultaneous VP shunt revision, followed by extended multidisciplinary rehabilitation. The coexistence of these three distinct congenital anomalies produced overlapping symptoms and delayed IHPS diagnosis. This case emphasises the need for vigilant reassessment of ongoing gastrointestinal symptoms in children with neural tube defects and explores embryological links between these conditions. Recognising such rare associations is vital for timely intervention and improved outcomes.
Comparison of outcomes after spinal column shortening for secondary tethered cord syndrome in pediatric versus adult patients: the University of Oklahoma experience.
Spinal column shortening (SCS) is an emerging alternative to traditional untethering in cases of secondary tethered cord syndrome. It was originally described and applied in adult patients with spinal dysraphism. In the more recent past, SCS has been used in pediatric patients. A comparison between pediatric and adult patients undergoing SCS has not been performed previously. A retrospective analysis was conducted on 19 patients (11 children, 8 adults) who underwent SCS procedures from November 30, 2020, to July 21, 2024, at the University of Oklahoma. Outcomes were assessed based on changes in pain, overall symptom burden, subjective bowel/bladder symptoms, and objective testing of urodynamic function. The median follow-up period was 30 months (range 10-41 months). Most vertebral column resections were performed at the T12 level (79%), with T10-L2 being the most common fusion level (68%). There were no significant preoperative differences in clinical features between children and adults. Both children and adults experienced significant reductions in pain (p = 0.002 and p = 0.018, respectively) and overall symptom burden (p < 0.001 and p = 0.003, respectively). Complete symptom resolution was achieved in 63% of children and 25% of adults. Improvements in objective urodynamic function were observed but were not statistically significant in either group (p = 0.082 for children, p = 0.351 for adults). However, only children reported significant improvement in bowel/bladder function (p < 0.01). The difference in surgical metrics or postoperative clinical features was not significant between children and adults. SCS procedures appear to be effective in reducing pain and overall symptom burden in both pediatric and adult patients with complex tethered cord syndrome. SCS seems to improve bowel/bladder symptoms in children specifically. Further research with larger cohorts and longer follow-up periods is warranted to confirm these findings and assess long-term outcomes.
Publicações recentes
Perioperative risk factors predicting CSF leak and retethering following tethered cord release for complex spinal lipomas.
Tethered Cord Syndrome in Pediatric and Adult Populations: A Retrospective Analysis of Outcomes and Associated Spinal Dysraphisms.
Sacral dimple: clinical perspectives of lesions hidden beneath the skin.
Double jeopardy in early infancy: aperta lipomyelomeningocele with Chiari II malformation complicated by infantile hypertrophic pyloric stenosis.
Spina bifida as a congenital neurodevelopmental condition: Developing a philosophy of health care transition across the lifespan.
📚 EuropePMC121 artigos no totalmostrando 166
Tethered Cord Syndrome in Pediatric and Adult Populations: A Retrospective Analysis of Outcomes and Associated Spinal Dysraphisms.
CureusSacral dimple: clinical perspectives of lesions hidden beneath the skin.
Clinical and experimental pediatricsDouble jeopardy in early infancy: aperta lipomyelomeningocele with Chiari II malformation complicated by infantile hypertrophic pyloric stenosis.
BMJ case reportsSpina bifida as a congenital neurodevelopmental condition: Developing a philosophy of health care transition across the lifespan.
Journal of pediatric rehabilitation medicineTandem Detethering: A Novel One-Stage Approach Combining Cervicothoracic Cord Release Followed by Filum Terminale Sectioning.
Journal of clinical medicineDelayed Diagnosis of Lumbosacral Lipomyelomeningocele With Tethered Cord: A Case Report.
CureusMultisystem Phenotypic Spectrum in Pediatric Heterotaxy Syndrome: A Case Series.
CureusSíndrome de médula anclada en pediatría. Presentación clínica, diagnóstico, etiología y resultados del tratamiento médico-quirúrgico.
Boletin medico del Hospital Infantil de MexicoComparative diagnostic accuracy of ultrasound and magnetic resonance imaging for spinal dysraphism in infants: insights from a single-center study.
Radiologie (Heidelberg, Germany)Closed spinal dysraphism: Think about it in the case of enuresis in children.
Radiology case reportsLipomyelomeningocele in a Newborn: A Case Report.
CureusGiant Lipofibromatosis Over Back Mimicking Thoracic Lipomyelomeningocele in Paediatric Age Group: Case Report and Review of Literature.
Journal of Indian Association of Pediatric SurgeonsClinical impact of fetal sac size on closed neural tube defects.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryThe effects of spinal dysraphism on the quality of life of pediatric patients and their families.
The journal of spinal cord medicine[Limited dorsal myeloschisis: From antenatal screening to postnatal evolution. About a series of cases from the Grand Est, Bourgogne and Franche-Comté].
Gynecologie, obstetrique, fertilite & senologieMediating Effects of Family and Clinical Characteristics on the Quality of Life of Children With Spina Bifida and Their Parents.
Journal of advanced nursingComparison of outcomes after spinal column shortening for secondary tethered cord syndrome in pediatric versus adult patients: the University of Oklahoma experience.
Journal of neurosurgery. PediatricsPerinatal Outcomes in Patients With Neural Tube Defects in a Middle-Income Setting.
Birth defects researchPosterior vertebral column resection for recurrent tethered cord syndrome: a 10-year case series.
Journal of neurosurgery. SpineA Supra-Numerary Limb Grafted Onto a Sacrococcygeal Mass in a Child With Spinal Dysraphism: Case Report, Dysmorphogenesis, and Management Review.
Birth defects researchManagement of a large pseudomeningocele and cerebrospinal fluid fistula after microsurgical resection of recurrent lipomyelomeningocele in children.
Neurosurgical focusAtypical Variants of Spinal Dysraphism: A Case Series.
Journal of the West African College of SurgeonsClinical profile of Korean children with spina bifida: a single-center prospective cohort study.
BMC pediatricsMorphometric analysis of the spinal cord in patients undergoing posterior vertebral column subtraction osteotomy for recurrent tethered cord syndrome.
Journal of neurosurgery. SpineBridging the spinal dysraphism spectrum between terminal myelocystocele and spinal cord lipoma: a report of two cases of true terminal lipomyelocystocele with holo-cord syrinx.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryEmbolization of an epidural arteriovenous fistula of the sacral nerve root with a neural tube defect: A case report.
International journal of surgery case reportsNavigating the transition: the crucial shift from pediatric to adult care for individuals living with spina bifida.
Neurosurgical focusRelationship between preoperative nutritional status assessed using anthropometric measures and postoperative complications in pediatric surgical patients.
Pediatric surgery internationalFirst incidence of extrarenal wilms tumor within the spinal canal in the adult population: a novel case report and literature review.
BMC urologyCartilage within lipomyelomeningocele and ulnar longitudinal deficiency syndrome as VACTERL association, alliance in SHH/GLI3, and Wnt pathway: illustrative case.
Journal of neurosurgery. Case lessonsAberrant Dorsal Nerve Root as a Concomitant Cause of Spinal Cord Tethering Associated with a Dorsal Type Lipomyelomeningocele in a Child With Caudal Agenesis.
Nigerian journal of clinical practiceContiguous diastematomyelia with tethered cord, intradural extramedullary dermoid tumor, and lipomyelomeningocele: A unique case of spinal dysraphism.
Clinical case reportsImmunohistochemical and Histopathological Characterization of Spina Bifida Defect Tissues Removed After Prenatal and Postnatal Surgical Repair.
Fetal and pediatric pathologyA Case Report of Fluoroscopically Guided Epidural Catheter Placement in a Parturient with History of Tethered Cord, Super-Morbid Obesity, and Risk for Difficult Airway.
A&A practiceUse of a machine learning algorithm with a focus on spinopelvic parameters to predict development of symptomatic tethered cord after initial untethering surgery.
Journal of neurosurgery. PediatricsClassification of and individual treatment strategies for complex tethered cord syndrome.
Frontiers in surgeryPreoperative interactive virtual simulation applying three-dimensional multifusion images using a haptic device for lumbosacral lipoma.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryLumbosacral lipoma in childhood, how strong is the evidence base? A systematic review.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryA Case of Perineal Hemangioma, External Genitalia Malformations, Lipomyelomeningocele, Vesicorenal Abnormalities, Imperforate Anus, and Skin Tag (PELVIS) Syndrome with Extensive Perineal Infantile Hemangioma.
Annals of dermatologyPerioperative complications and secondary retethering after pediatric tethered cord release surgery.
Journal of neurosurgery. PediatricsSuccessful sacral neuromodulation treatment of refractory faecal incontinence in a patient with spina bifida and partial sacral agenesis.
BMJ case reportsEstimating the Glomerular Filtration Rate in Pediatric Patients With Neurogenic Bladder: A Comparison Between Creatinine- and Cystatin C-Equations.
CureusThe loop-tail mouse model displays open and closed caudal neural tube defects.
Disease models & mechanisms[Classification and microsurgical treatment of primary tethered cord syndrome in adults].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciencesA rare case of thoracic lipomyelomeningocele in a young female: A case report.
Radiology case reportsNephrogenic rest vs immature teratoma associated with lumbosacral lipomyelomeningocele: a case report and review of the literature.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryTransition from partial to near-total/radical resection of spinal cord lipomas.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryPrenatally diagnosed fetal thoraco-lumbar spine duplication associated with lipomyelomeningocele: An extremely rare case of split cord malformation.
Turkish journal of obstetrics and gynecologyAnalysis of factors affecting permanent clean intermittent catheterization and bladder function after primary neurosurgical repair of lipomyelomeningocele.
Neurourology and urodynamicsLate diagnosis of dorsolumbar lipomyelomeningocele with tethered cord in a middle aged adult: A case report from Nepal.
Radiology case reportsNovel use of nonpenetrating titanium clips for pediatric primary spinal dural closure: A technical note.
Clinical neurology and neurosurgerySplit Notochord Syndrome with Spinal Column Duplication and Spinal Cord Lipoma: A Case Report.
Children (Basel, Switzerland)Dorsolumbar parasitic twin associated with lipomyelomeningocele: a case report from a tertiary teaching hospital, Ethiopia, East Africa.
Radiology case reportsCharacterizing syringomyelia and its clinical significance in 140 patients with lipomyelomeningocele.
Journal of neurosurgery. PediatricsHigh prevalence of gram-negative and multiorganism surgical site infections after pediatric complex tethered spinal cord surgery: a multicenter study.
Journal of neurosurgery. PediatricsRecurrent Tethering in Conus Lipomas: A Late Complication Not to Be Ignored.
World neurosurgeryIntracranial subdural hemorrhage following closed neural tube defect repair: illustrative case.
Journal of neurosurgery. Case lessonsSacral myolipoma with involuntary contraction causing tethered cord syndrome: illustrative case.
Journal of neurosurgery. Case lessonsProgressive-Tension Sutures in Reconstruction of Posterior Trunk Defects in Pediatric Patients: A Prospective Series.
Plastic and reconstructive surgeryRepair of refractory postoperative cerebrospinal fluid leakage using a reversed dermis flap in a pediatric lipomyelomeningocele patient.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryTethered Cord Syndrome Associated With Lumbar Lipomyelomeningocele: A Case Report.
CureusPhysiological rapid growth of spinal lipoma in the early postnatal period.
Journal of neurosurgery. PediatricsSpinal column shortening for tethered cord syndrome: a systematic review and individual patient data meta-analysis.
Journal of neurosurgery. PediatricsSpinal cord detethering without laminectomy or laminotomy.
Surgical neurology internationalChaotic lipoma with proximal syrinx -a (not so) rare variant - review of the literature, possible embryology and management.
British journal of neurosurgeryRetethering risk in pediatric spinal lipoma of the conus medullaris.
Journal of neurosurgery. PediatricsRisk factors for pre-operative functional deterioration in children with lipomyelomeningocele.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryDiscrepancies in Educational Needs for Transition in Adolescents and Young Adults with Spina Bifida in South Korea: Use of the Borich Needs Assessment Model.
Journal of pediatric nursingSpinal column shortening for secondary tethered cord syndrome: radiographic, clinical, patient-reported, and urodynamic short-term outcomes.
Journal of neurosurgery. PediatricsClosed spinal dysraphism in a 6-month-old mixed breed dog.
Veterinarni medicinaLumbosacral Lipomyelomeningocele with Lateral Attachment to Neural Placode: Case Illustration.
Pediatric neurosurgeryDynamic mapping using an electrified ultrasonic aspirator in lipomyelomeningocele and spinal cord detethering surgery-a feasibility study.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryEarly- and long-term surgical outcomes in 109 children with lipomyelomeningocele.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryPosterior Vertebral Column Subtraction Osteotomy for Recurrent Tethered Cord Syndrome: A Multicenter, Retrospective Analysis.
NeurosurgeryQuantitative Computed Tomography Assessment of Bone Deficits in Ambulatory Children and Adolescents with Spina Bifida: Importance of Puberty.
JBMR plusMultidisciplinary Management of Tethered Spinal Cord Syndrome in Children: Operationalizing an Outpatient Patient-Centered Workflow.
Journal of multidisciplinary healthcareBladder Volume Assessment in Pediatric Patients With Neurogenic Bladder: Is Ultrasound an Accurate Method?
UrologyPsychosocial outcomes for adults with spina bifida: a scoping review protocol.
JBI evidence synthesisHigh Prevalence of Gram-Negative Rod and Multi-Organism Surgical Site Infections after Pediatric Complex Tethered Spinal Cord Surgery: Preliminary Report from a Single-Center Study.
Pediatric neurosurgeryLimited dorsal myeloschisis with a contiguous stalk to human tail-like cutaneous appendage, associated with a lipoma of conus medullaris: A case report.
International journal of surgery case reportsNeurosurgical management of conus lipoma in Canada: a multi-center survey.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryEnlargement of Extraspinal Cysts in Spinal Dysraphism : A Reason for Early Untethering.
Journal of Korean Neurosurgical SocietyEmbryology of Spinal Dysraphism and its Relationship to Surgical Treatment.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiquesRepair of giant lumbosacral pseudomeningocele with fast-resorbing polymer mesh in a pediatric patient operated for posterior dysraphism.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgerySuccessful Treatment of Well-Developed Accessory Lower Limb Associated with Spinal Dysraphism.
World journal of plastic surgerySyringomyelia in children with closed spinal dysraphism: long-term outcomes after surgical intervention.
Journal of neurosurgery. PediatricsLong-term urological outcomes of spinal lipoma after prophylactic untethering in infancy: real-world outcomes by lipoma anatomy.
Spinal cordGiant Symptomatic Meningocele as a Delayed, Adult Complication of Lipomyelomeningocele.
World neurosurgeryCervical Lipomyelomeningocele Presenting with Progressive Motor Deficit: A Case Report and Review of the Literature.
Pediatric neurosurgeryPredictors of surgical treatment in children with tethered fibrofatty filum terminale.
Journal of neurosurgery. PediatricsThe role of sacral laminoplasty in the management of spina bifida and sacral cystic lesions: case series.
Neurosurgical focusCongenital Spinal Lipomatous Malformations. Part 1. Spinal Lipomas, Lipomyeloceles, and Lipomyelomeningoceles.
Fetal and pediatric pathologyCervical Lipomyelocele with Congenital Inclusion Cyst.
World neurosurgeryScientific methodology of the development of the Guidelines for the Care of People with Spina Bifida: An initiative of the Spina Bifida Association.
Disability and health journalRadical excision of lumbosacral lipoma: an early experience of "followers".
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryVisual Diagnosis: A 19-month-old Girl with a Lumbosacral Mass.
Pediatrics in reviewDecreased MEPs during subcutaneous dissection for untethering surgery of a "true" lipomyelomeningocele: aggravated traction of the spinal cord by release of the sac from the original nest.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgerySchuurs-Hoeijmakers syndrome in two patients from Japan.
American journal of medical genetics. Part AMicrosurgical efficacy in 326 children with tethered cord syndrome: a retrospective analysis.
Neural regeneration researchContiguous Diastematomyelia with Lipomyelomeningocele in Each Hemicord-an Exceptional Case of Spinal Dysraphism.
World neurosurgeryDynamic magnetic resonance imaging parameters for objective assessment of the magnitude of tethered cord syndrome in patients with spinal dysraphism.
Acta neurochirurgicaPredictive value of intraoperative bulbocavernosus reflex during untethering surgery for post-operative voiding function.
Clinical neurophysiology : official journal of the International Federation of Clinical NeurophysiologySpinal Cord Stimulation in Adult Tethered Cord Syndrome: Case Report and Review of the Literature.
World neurosurgeryFetal lipomyelomeningocele: A closed neural tube defect diagnosed at second-trimester ultrasound examination.
Journal of clinical ultrasound : JCUEpendyma-Lined Canal with Surrounding Neuroglial Tissues in Lumbosacral Lipomatous Malformations: Relationship with Retained Medullary Cord.
Pediatric neurosurgeryDevelopment of best practices to minimize wound complications after complex tethered spinal cord surgery: a modified Delphi study.
Journal of neurosurgery. PediatricsA Rare Case of "Human Tail" Associated with Lipomyelomeningocele and Tethered Cord.
Journal of pediatric neurosciencesUsing subdural strip electrodes to define functional sensory nerves and the most inferior functional portion of the conus medullaris during detethering surgeries for tethered cord syndrome: a pilot study.
Journal of neurosurgery. SpineIceberg hemangioma: A segmental cutaneous lesion marking extensive extracutanous involvement.
JAAD case reportsSurgical Outcomes of Pediatric Patients with Asymptomatic Tethered Cord Syndrome.
Asian spine journalAdult Versus Pediatric Tethered Cord Syndrome: Clinicoradiological Differences and its Management.
Asian journal of neurosurgeryAcute Communicating Hydrocephalus as Spinal Cord Surgery Complication in Patient with Lumbar Lipomyelocele.
World neurosurgeryTailored Strategies to Manage Cerebrospinal Fluid Leaks or Pseudomeningocele After Surgery for Tethered Cord Syndrome.
World neurosurgeryThe pathology of lumbosacral lipomas: macroscopic and microscopic disparity have implications for embryogenesis and mode of clinical deterioration.
HistopathologyFatty filum terminale (FFT) as a secondary tethering element in children with closed spinal dysraphism.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryDe Novo Spinal Dural Arteriovenous Fistula in a Patient with a Lipomyelomeningocele: Case Report.
World neurosurgeryGenome-wide sequencing expands the phenotypic spectrum of EP300 variants.
European journal of medical geneticsTransgenerational Inheritance of Familial Lipomyelomeningocele.
Journal of child neurologyUrologic self-management through intermittent self-catheterization among individuals with spina bifida: A journey to self-efficacy and autonomy.
Journal of pediatric rehabilitation medicineMinimally invasive endoscopic spinal cord untethering: case report.
Journal of spine surgery (Hong Kong)Chronic Renal Failure Secondary to Unrecognized Neurogenic Bladder in A Child with Myelodysplasia.
Iranian journal of child neurologyLong-term evaluation of intraoperative neurophysiological monitoring-assisted tethered cord surgery.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryLipomyelomeningocele for the urologist: Should we view it the same as myelomeningocele?
Journal of pediatric urologyKlippel-Feil Syndrome Associated with Sacral Agenesis, Low Lying Cord, Lipomyelomeningocele and Split Cord Malformation Presenting with Tethered Cord Syndrome: Pentads Neural Tube Defects Spread along Whole Spinal Axis.
Journal of pediatric neurosciencesNoncontiguous Double Spinal Lipoma with Tethered Cord and Polydactyly: Two Different Embryological Events in One Patient.
Journal of pediatric neurosciencesSurgical management of lipomyelomeningocele in children: Challenges and considerations.
Surgical neurology internationalThe Rare Association of Spina Bifida and Extrarenal Wilms Tumor: A Case Report and Review of the Literature.
World neurosurgerySpinal column shortening for tethered cord syndrome associated with myelomeningocele, lumbosacral lipoma, and lipomyelomeningocele in children and young adults.
Journal of neurosurgery. PediatricsUrological Outcomes of Myelomeningocele and Lipomeningocele.
Current urology reportsLateral lipomyelomeningocele of the hemicord with split cord malformation type I revealed by 3D heavily T2-weighted MR imaging.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryImage Gallery: PELVIS syndrome.
The British journal of dermatologyOssified dysraphic hamartoma with lipomyelocoele/lipomyelomeningocoele-A rare radiological entity.
Clinical imagingLUMBAR syndrome: A case manifesting as cutaneous infantile hemangiomas of the lower extremity, perineum and gluteal region, and a review of published work.
The Journal of dermatologyThe Currarino triad: What pediatric surgeons need to know.
Journal of pediatric surgeryCaudal Duplication Syndrome: the Vital Role of a Multidisciplinary Approach and Staged Correction.
European journal of pediatric surgery reportsSegmental Infantile Hemangioma With Minimal or Arrested Growth in LUMBAR Syndrome.
Actas dermo-sifiliograficasUse of magnetic resonance imaging to detect occult spinal dysraphism in infants.
Journal of neurosurgery. PediatricsUrological Outcome of the Xiao Procedure in Children with Myelomeningocele and Lipomyelomeningocele Undergoing Spinal Cord Detethering.
The Journal of urologyDifferentiating Closed Versus Open Spinal Dysraphisms on Fetal MRI.
AJR. American journal of roentgenologyComparative Study of Untethering and Spine-Shortening Surgery for Tethered Cord Syndrome in Adults.
Global spine journalAdult cervicothoracic lipomyelomeningocele.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of AustralasiaPaediatrics: Randomized study of the Xiao procedure.
Nature reviews. UrologyIntracranial subdural empyema after surgery for lumbar lipomyelomeningocele: A rare complication.
Surgical neurology internationalA Rare Triad of Giant Occipital Encephalocele with Lipomyelomeningocele, Tetralogy of Fallot, and Situs Inversus.
Journal of radiology case reportsLack of efficacy of an intradural somatic-to-autonomic nerve anastomosis (Xiao procedure) for bladder control in children with myelomeningocele and lipomyelomeningocele: results of a prospective, randomized, double-blind study.
Journal of neurosurgery. PediatricsAssociation between clean intermittent catheterization and urinary tract infection in infants and toddlers with spina bifida.
Journal of pediatric urologySpinal lipoma as a dysembryogenetic anomaly: Four unusual cases of ectopic iliac rib within the spinal lipoma.
Birth defects research. Part A, Clinical and molecular teratologyRadiographic predictors of deterioration in patients with lumbosacral lipomas.
Journal of neurosurgery. PediatricsSpinal cord stimulation for recurrent tethered cord syndrome in a pediatric patient: case report.
Journal of neurosurgery. PediatricsPrenatal diagnosis of tethered spinal cord associated with sacrococcygeal teratoma.
Journal of clinical ultrasound : JCURandomized clinical trial of acetazolamide administration and/or prone positioning in mitigating wound complications following untethering surgeries.
Journal of neurosurgery. PediatricsParasitic twin--a supernumerary limb associated with spinal malformations. A case report.
Acta neurochirurgicaThe natural history and management of patients with congenital deficits associated with lumbosacral lipomas.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryA case of tubular adenoma developing after bladder augmentation: Case report and literature review.
International journal of surgery case reportsPrenatal diagnosis of lipomyelomeningocele by ultrasound and magnetic resonance imaging (MRI).
Clinical and experimental obstetrics & gynecologyContiguous triple spinal dysraphism associated with Chiari malformation Type II and hydrocephalus: an embryological conundrum between the unified theory of Pang and the unified theory of McLone.
Journal of neurosurgery. PediatricsCloacal reconstruction after a complex treatment of perineal haemangioma in a variant of PELVIS syndrome.
BMC pediatricsMassive Lumbosacral Subcutaneous Exudate After Surgical Treatment of a Large Lipomyelocele: Case Report and Literature Review.
MedicineSymptomatic retethering of the spinal cord in postoperative lipomyelomeningocele patients: a meta-analysis.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryPhenotypic variability of a terminal 7q deletion/8q duplication in Korean siblings.
Annals of laboratory medicineRhabdomyomatous mesenchymal hamartoma presenting as a sacral skin tag in two neonates with spinal dysraphism.
Journal of cutaneous pathologyExtraspinal type I dural arteriovenous fistula with a lumbosacral lipomyelomeningocele: a case report and review of the literature.
Case reports in neurological medicineReticular infantile hemangiomas with minimal or arrested growth associated with lipoatrophy.
Journal of the American Academy of DermatologyMorphometric analysis of lumbar pedicles in patients with spinal dysraphism.
Pediatric neurosurgerySpondylocostal dysostosis with lipomyelomeningocele: Case report and review of the literature.
Journal of pediatric neurosciencesLumbosacral lipomyelomeningocele with anomalous osseous limb in a 3-month-old female.
Radiology case reportsAssociações
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Sacral dimple: clinical perspectives of lesions hidden beneath the skin.
- Tethered Cord Syndrome in Pediatric and Adult Populations: A Retrospective Analysis of Outcomes and Associated Spinal Dysraphisms.
- Mediating Effects of Family and Clinical Characteristics on the Quality of Life of Children With Spina Bifida and Their Parents.
- Double jeopardy in early infancy: aperta lipomyelomeningocele with Chiari II malformation complicated by infantile hypertrophic pyloric stenosis.
- Comparison of outcomes after spinal column shortening for secondary tethered cord syndrome in pediatric versus adult patients: the University of Oklahoma experience.
- Perioperative risk factors predicting CSF leak and retethering following tethered cord release for complex spinal lipomas.
- Spina bifida as a congenital neurodevelopmental condition: Developing a philosophy of health care transition across the lifespan.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:268835(Orphanet)
- MONDO:0012296(MONDO)
- GARD:10053(GARD (NIH))
- Busca completa no PubMed(PubMed)
- Q10318855(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
