Oligodendroglioma grau III da OMS com características morfológicas malignas focais ou difusas (pleomorfismo nuclear proeminente, mitoses e celularidade aumentada).
Introdução
O que você precisa saber de cara
Oligodendroglioma grau III da OMS com características morfológicas malignas focais ou difusas (pleomorfismo nuclear proeminente, mitoses e celularidade aumentada).
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
1/2k
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Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Linha do tempo da pesquisa
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Genética e causas
O que está alterado no DNA e como passa nas famílias
Genes associados
2 genes identificados com associação a esta condição. Padrão de herança: Not applicable.
Plays a role in intermediary metabolism and energy production (PubMed:19228619, PubMed:22416140). It may tightly associate or interact with the pyruvate dehydrogenase complex (PubMed:19228619, PubMed:22416140)
Mitochondrion
D-2-hydroxyglutaric aciduria 2
A neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features. Both a mild and a severe phenotype exist. The severe phenotype is homogeneous and is characterized by early infantile-onset epileptic encephalopathy and cardiomyopathy. The mild phenotype has a more variable clinical presentation. Diagnosis is based on the presence of an excess of D-2-hydroxyglutaric acid in the urine.
Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. Is a component of the double-stranded telomeric DNA-binding TRF1 complex which is involved in the regulation of telomere length by cis-inhibition of telomerase. Also acts as a single-stranded telomeric DNA-binding protein and thus may act as a downstream effector of the TRF1 complex and may transduce information about telomere maintenance and/or length to the telomere terminus
NucleusChromosome, telomere
Tumor predisposition syndrome 3
An autosomal dominant disorder characterized by an increased risk for the development of various types of benign and malignant neoplasms throughout life, with age-dependent penetrance. Affected individuals can develop neoplasms involving epithelial, mesenchymal, and neuronal tissues, as well as lymphoid and myeloid cancers. The disorder is associated with elongated telomeres.
Variantes genéticas (ClinVar)
550 variantes patogênicas registradas no ClinVar.
Classificação de variantes (ClinVar)
Distribuição de 1 variantes classificadas pelo ClinVar.
Vias biológicas (Reactome)
18 vias biológicas associadas aos genes desta condição.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Oligodendroglioma anaplásico
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Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.
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244 ensaios clínicos encontrados, 12 ativos.
Publicações mais relevantes
Anesthesia management in a pregnant woman with a giant temporoparietal anaplastic oligodendroglioma: a case report.
Brain tumors during pregnancy are rare and pose unique challenges in diagnosis, management, and anesthetic care. This report is novel owing to the rare coexistence of a giant anaplastic oligodendroglioma with an ongoing pregnancy requiring urgent dual surgical interventions. A 27-year-old, right-handed, Middle Eastern Saudi woman at 35 weeks of gestation presented with neurological symptoms, including partial loss of consciousness, left-sided ptosis, and severe headaches. Imaging revealed a large left temporoparietal mass with significant midline shift, diagnosed as an anaplastic oligodendroglioma. She underwent an emergency cesarean section and craniotomy under general anesthesia. Postoperative recovery was uneventful for both the mother and the newborn. This case highlights the critical importance of multidisciplinary coordination, individualized anesthetic planning, and timely surgical decision-making in managing complex neurosurgical cases during pregnancy. The combined obstetric-neurosurgical approach contributed to a favorable maternal and neonatal outcome.
Hematological Malignancies With Multiple Primary Cancers: A Rare Case Presentation.
Two or more primary cancers that arise in two different patients are referred to as multiple primary cancers. We record those cases because optimal therapy requires interdisciplinary cooperation. A 53-year-old male presented with intermittent hematuria for one year, fever, burning micturition, appetite loss, and a 3 kg weight loss over 2 months. His CBC showed 81% atypical cells, and bone marrow aspiration and flow cytometry indicated Precursor B-ALL. He started on the BFM-2002-protocol but had persistent hematuria. The USG of the whole abdomen revealed a urinary bladder mass. TURBT and histopathology confirmed low-grade, noninvasive papillary urothelial neoplasm. Thus, he was diagnosed with Precursor B-ALL and Low-Grade Papillary Urothelial Neoplasm Noninvasive. A 53-year-old male with a history of anaplastic oligodendroglioma (diagnosed in 2022) presented to the emergency with altered sensorium, headache, and convulsions. He had received radiotherapy and chemotherapy for the past year. In December 2023, he experienced convulsions again due to a recurrence of the oligodendroglioma. His CBC showed an increasing total leukocyte count, reaching 100,000 over five months. Bone marrow and molecular studies indicated a myeloproliferative neoplasm, specifically chronic myeloid neoplasm (CMN) in the chronic phase, with BCR-ABL1 p210 positive. He was diagnosed with recurrent anaplastic oligodendroglioma (WHO Grade 3) and CMN in the chronic phase. An increased prevalence of second primary malignancy is anticipated due to the rising cancer burden and the careful screening of index initial malignancy throughout therapy. Determining the best course of action requires careful staging of the cancer and discussion by a multidisciplinary team.
Investigation of mismatch repair protein expression in glioma.
Mismatch repair (MMR) proteins are essential for maintaining genomic stability, and their dysfunction contributes to tumorigenesis in several malignancies. However, their role in glioma remains insufficiently defined. This study evaluated MMR protein expression in Tunisian glioma patients and examined its clinicopathological and prognostic significance. Ninety-five glioma samples were retrospectively analyzed. MMR protein expression was assessed by immunohistochemistry on formalin-fixed, paraffin-embedded tissues. Survival outcomes were evaluated using Kaplan-Meier analysis with Log-Rank testing. MMR expression was retained in 65 tumors (68.4 %) and lost in 30 (31.6 %). Loss of MLH1/PMS2 was observed in 16 tumors, MSH2/MSH6 loss in 12, and complete loss of all MMR proteins in two tumors. The distribution of MMR deficiency varied by histological subtype. Among pilocytic astrocytomas, 7 cases exhibited MMR deficiency, predominantly MLH1/PMS2 (n = 5). Two astrocytomas IDH mutant showed either MLH1/PMS2 or MSH2/MSH6 loss. Altered MMR profiles were also identified in oligodendroglioma IDH-mutant, 1p/19q co-deleted (n = 3), oligoastrocytoma NOS (n = 1), and anaplastic oligodendroglioma NOS (n = 1). In glioblastoma, IDH-wildtype, 14 cases showed heterodimer loss (MLH1/PMS2 or MSH2/MSH6), and two tumors demonstrated complete loss of all MMR proteins. Survival analysis revealed a significant prognostic effect exclusively in glioblastomas IDH-wildtype, where MMR deficiency was associated with worse survival (Log-rank test, p < 0.0001). MMR deficiency is relatively frequent in gliomas and carries prognostic significance, particularly in glioblastoma IDH-wildtype. Incorporating MMR status into molecular profiling may enhance risk stratification and inform therapeutic decision-making in glioma management.
Long-Term Remission of Recurrent Anaplastic Oligodendroglioma With WT-1-Specific CD8+ T-Cell Therapy: A Case Report.
We report a case of complete remission in anaplastic oligodendroglioma following adoptive cell therapy (ACT) with autologous Wilms tumor 1 (WT-1)-specific CD8+ T cells. A 40-year-old woman referred to our hospital for adjuvant chemotherapy after recurrent anaplastic oligodendroglioma initially presented with a left frontal tumor, diagnosed through seizure onset, and subtotal resection confirmed oligodendroglioma (WHO grade 2). Radiation therapy treated the residual tumor, achieving partial remission until recurrence 2.5 years later when malignant transformation to anaplastic oligodendroglioma (WHO grade 3) occurred following a second craniotomy. After three cycles of procarbazine, lomustine, and vincristine chemotherapy, the residual tumor stabilized for 3 years. However, follow-up MRI identified a new enhancing lesion, prompting a third craniotomy. Recurrent anaplastic oligodendroglioma was confirmed, and adjuvant proton beam therapy and temozolomide chemotherapy were initiated. Two years later, another enhancing lesion appeared on the adjacent medial frontal lobe. Following multidisciplinary review, we introduced WT-1-specific ACT. Although transient swelling was observed 1 month post-therapy, the tumor demonstrated a response within 3-9 months. Continued regression led to complete remission-confirmed via MRI at the 15-month follow-up and sustained for 4.7 years. The patient's peripheral blood monocyte profiles and immune-associated cytokine analysis indicated T-cell activation following WT-1 sensitization.
Do clinical outcomes in individuals with malignant gliomas differ between sexes?
Sex-related differences in the epidemiology of malignant gliomas are acknowledged; however, information regarding their clinical characteristics and outcomes after surgery is limited. To identify sex-specific differences of all patients with high-grade glioma at our institution and assessed clinical outcomes and prognostic factors. This single-center study included those who underwent surgery for malignant gliomas between 2010 and 2020. Categorical, normally distributed, and skewed continuous variables were compared between men and women using the chi-square test, independent samples t-test, and Mann-Whitney U test, respectively. Survival was calculated using the log-rank and Kaplan-Meier methods. In total, 621 patients with WHO grade IV gliomas were identified (370 (59.58%) male). Men were significantly younger, underwent surgery faster after imaging diagnosis, and had a slightly higher surgical complications incidence than women. Women reported a worse preoperative performance status. Multivariate analysis showed that sex did not affect survival, surgical complications, nicotine or alcohol abuse, or preoperative tumor volume. Age, Karnofsky performance status, neurosurgical resection, and adjuvant radiotherapy with temozolomide showed a survival advantage. Men are diagnosed with malignant glioma at a younger age than women; however, no advantage in clinical outcomes was observed. No sex-related differences were observed.
Publicações recentes
Anesthesia management in a pregnant woman with a giant temporoparietal anaplastic oligodendroglioma: a case report.
Hematological Malignancies With Multiple Primary Cancers: A Rare Case Presentation.
Adjuvant chemoradiotherapy with procarbazine, lomustine, and vincristine (PCV) or temozolomide for 1p/19q Co-deleted anaplastic oligodendroglioma: a systematic review and network meta-analysis.
Designing a web-based platform for dynamic estimation of individualized conditional survival in grade 3 gliomas.
Combined temozolomide, immunotherapy and radiotherapy in a patient with anaplastic oligodendroglioma and multiple extracranial metastases: A rare case report.
📚 EuropePMC186 artigos no totalmostrando 198
Anesthesia management in a pregnant woman with a giant temporoparietal anaplastic oligodendroglioma: a case report.
Journal of medical case reportsHematological Malignancies With Multiple Primary Cancers: A Rare Case Presentation.
Case reports in hematologyAdjuvant chemoradiotherapy with procarbazine, lomustine, and vincristine (PCV) or temozolomide for 1p/19q Co-deleted anaplastic oligodendroglioma: a systematic review and network meta-analysis.
BMC cancerDesigning a web-based platform for dynamic estimation of individualized conditional survival in grade 3 gliomas.
Discover oncologyCombined temozolomide, immunotherapy and radiotherapy in a patient with anaplastic oligodendroglioma and multiple extracranial metastases: A rare case report.
MedicineInvestigation of mismatch repair protein expression in glioma.
Annals of diagnostic pathologyIn silico analysis reveals distinct changes in markers of epithelial to mesenchymal transition in glioma subtypes.
Biomolecules & biomedicineShared decision-making interventions in neuro-oncology practice: a systematic review.
Journal of neuro-oncologyLong-Term Remission of Recurrent Anaplastic Oligodendroglioma With WT-1-Specific CD8+ T-Cell Therapy: A Case Report.
Brain tumor research and treatmentRadiation-induced osteosarcoma of the frontoparietal calvaria 6 years after oligodendroglioma treatment: illustrative case.
Journal of neurosurgery. Case lessonsIntegrating nutritional status and hematological biomarkers for enhanced prognosis prediction in glioma patients: A systematic review.
Clinical nutrition ESPENExpanded Use of Vorasidenib in Non-Enhancing Recurrent CNS WHO Grade 3 Oligodendroglioma.
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American journal of translational researchReconstruction of Complex Scalp Defects in Different Locations: Suggestions for Puzzle.
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BMC cancerRadiation Therapy for Grade 3 Gliomas: Correlation of MRI Findings With Prognosis.
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Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko[Clinicopathological and molecular genetic characteristics of adult IDH wild-type diffuse gliomas].
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Frontiers in neurologyCorrelation between FDG-PET uptake and survival in patients with primary brain tumors.
American journal of nuclear medicine and molecular imagingDifferential expression of stem cell markers in proliferating cells in glioma.
Journal of cancer research and clinical oncologyEstablishment and Validation of the Detection of TERT Promoter Mutations by Human Gliomas U251 Cell Lines.
BioMed research international[Dynamic11C-methionine PET/CT in differential diagnosis of brain gliomas].
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Molecular and clinical oncologyA single institution retrospective analysis on survival based on treatment paradigms for patients with anaplastic oligodendroglioma.
Journal of neuro-oncologyPatient-specific virtual reality technology for complex neurosurgical cases: illustrative cases.
Journal of neurosurgery. Case lessonsHypermetabolism and impaired cerebrovascular reactivity beyond the standard MRI-identified tumor border indicate diffuse glioma extended tissue infiltration.
Neuro-oncology advancesGliomas - An experience based on molecular markers.
Journal of family medicine and primary careDistinct TERT promoter C228T and C250T mutations in a patient with an oligodendroglioma: A case report.
Neuropathology : official journal of the Japanese Society of NeuropathologyEffects of Aerobic and Flexibility Training on Physiological and Psychosocial Function in a Patient with Anaplastic Oligodendroglioma: A Case Report.
Journal of rehabilitation medicine. Clinical communicationsTEMOBIC: Phase II Trial of Neoadjuvant Chemotherapy for Unresectable Anaplastic Gliomas: An ANOCEF Study.
The oncologistIDH-mutant gliomas with additional class-defining molecular events.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, IncChallenges and Perspectives of Standard Therapy and Drug Development in High-Grade Gliomas.
Molecules (Basel, Switzerland)CyTOF Analysis Reveals a Distinct Immunosuppressive Microenvironment in IDH Mutant Anaplastic Gliomas.
Frontiers in oncologyCase Report: Single-Cell Transcriptomic Analysis of an Anaplastic Oligodendroglioma Post Immunotherapy.
Frontiers in oncologyProlonged benefit to pembrolizumab in anaplastic oligodendroglioma patient with mismatch repair deficiency: a case report.
Anti-cancer drugsPhase I trial of intracerebral convection-enhanced delivery of carboplatin for treatment of recurrent high-grade gliomas.
PloS oneTreatment of patients with glioma during the COVID-19 pandemic: what we learned and what we take home for the future.
Neurosurgical focusSurvival outcome and prognostic factors in anaplastic oligodendroglioma: a single-institution study of 95 cases.
Scientific reportsAnaplastic Oligodendroglioma - Is Adjuvant Radiotherapy Mandatory following Maximal Surgical Resection?: Grade 3 Oligo Radiotherapy.
Clinical neurology and neurosurgeryPhase II Trial of Palbociclib in Recurrent Retinoblastoma-Positive Anaplastic Oligodendroglioma: A Study from the Spanish Group for Research in Neuro-Oncology (GEINO).
Targeted oncologyAdditional genetic alterations in BRAF-mutant gliomas correlate with histologic diagnoses.
Journal of neuro-oncologyMultiple metastases to the bone and bone marrow from a 1p/19q-codeleted and IDH2-mutant anaplastic oligodendroglioma: a case report and literature review.
Neuro-oncology advancesSustained response to erlotinib and rapamycin in a patient with pediatric anaplastic oligodendroglioma.
Pediatric blood & cancerAlpha Internexin: A Surrogate Marker for 1p/19q Codeletion and Prognostic Marker in Anaplastic (WHO grade III) Gliomas.
Neurology IndiaPembrolizumab Activity in Recurrent High-Grade Gliomas with Partial or Complete Loss of Mismatch Repair Protein Expression: A Monocentric, Observational and Prospective Pilot Study.
CancersHigh-grade gliomas with isocitrate dehydrogenase wild-type and 1p/19q codeleted: Atypical molecular phenotype and current challenges in molecular diagnosis.
Neuropathology : official journal of the Japanese Society of Neuropathology[Spinal cord metastasis of anaplastic oligodendroglioma of the brain without recurrence of primary tumor. Ccase report and literature review].
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko5-Aminolevulinic Acid Multispectral Imaging for the Fluorescence-Guided Resection of Brain Tumors: A Prospective Observational Study.
Frontiers in oncologySimultaneous Bilateral Femoral Neck Fracture Due to a Tonic-Clonic Seizure and High-Dose Steroid Therapy.
Arthroplasty todayRole of the default mode resting-state network for cognitive functioning in malignant glioma patients following multimodal treatment.
NeuroImage. ClinicalSurvival, Prognostic Factors, and Volumetric Analysis of Extent of Resection for Anaplastic Gliomas.
Cancer research and treatmentPhase I clinical trial of temsirolimus and perifosine for recurrent glioblastoma.
Annals of clinical and translational neurology5-ALA False-Positive in Anaplastic Oligodendroglioma, IDH-mutant and 1p/19q-codeleted.
Surgical technology internationalA phase I trial of surgical resection with Gliadel Wafer placement followed by vaccination with dendritic cells pulsed with tumor lysate for patients with malignant glioma.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of AustralasiaInvolvement of the Olfactory Apparatus by Gliomas.
AJNR. American journal of neuroradiologySpinal leptomeningeal oligodendrogliomatosis after resection of cerebral anaplastic oligodendoglioma with 1p19q Co-deletion - A case report.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of AustralasiaAbility of Radiomics in Differentiation of Anaplastic Oligodendroglioma From Atypical Low-Grade Oligodendroglioma Using Machine-Learning Approach.
Frontiers in oncologyHigh-grade Glioma Masquerading as a Small Cerebral Hemorrhage: A Case Report.
Yonago acta medicaCDKN2A homozygous deletion is a strong adverse prognosis factor in diffuse malignant IDH-mutant gliomas.
Neuro-oncology[Repetitive resection and intrasurgery radiation therapy of brain malignant gliomas: history of question and modern state of problem].
Zhurnal voprosy neirokhirurgii imeni N. N. BurdenkoRadiomics-Based Machine Learning Technology Enables Better Differentiation Between Glioblastoma and Anaplastic Oligodendroglioma.
Frontiers in oncologyExperience Profiling of Fluorescence-Guided Surgery I: Gliomas.
Brain tumor research and treatmentThe Korean Society for Neuro-Oncology (KSNO) Guideline for WHO Grade III Cerebral Gliomas in Adults: Version 2019.01.
Brain tumor research and treatmentKi-67 and MCM6 labeling indices are correlated with overall survival in anaplastic oligodendroglioma, IDH1-mutant and 1p/19q-codeleted: a multicenter study from the French POLA network.
Brain pathology (Zurich, Switzerland)Repeat Resection and Intraoperative Radiotherapy for Malignant Gliomas of the Brain: A History and Review of Current Techniques.
World neurosurgeryCommon Molecular Alterations in Canine Oligodendroglioma and Human Malignant Gliomas and Potential Novel Therapeutic Targets.
Frontiers in oncologyExtent of resection and survival for oligodendroglioma: a U.S. population-based study.
Journal of neuro-oncologyNeuro-Oncology Clinical Debate: PCV or temozolomide in combination with radiation for newly diagnosed high-grade oligodendroglioma.
Neuro-oncology practiceA novel PTPRZ1-ETV1 fusion in gliomas.
Brain pathology (Zurich, Switzerland)Reclassification of Mongolian Diffuse Gliomas According to the Revised 2016 World Health Organization Central Nervous System Tumor Classification.
Journal of pathology and translational medicine[IDH、TERT and 1p/19q predicting clinical outcomes in patients with anaplastic oligodendroglioma].
Zhonghua yi xue za zhiAnaplastic Oligodendroglioma with Transdural Extension.
World neurosurgeryBone metastases from a 1p/19q codeleted and IDH1-mutant anaplastic oligodendroglioma: a case report.
Journal of medical case reportsPotential influence of IDH1 mutation and MGMT gene promoter methylation on glioma-related preoperative seizures and postoperative seizure control.
SeizureScalp Metastasis of Anaplastic Oligodendroglioma.
World neurosurgeryPattern of failure in anaplastic glioma patients with an IDH1/2 mutation.
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]Incidence trends of adult malignant brain tumors in Finland, 1990-2016.
Acta oncologica (Stockholm, Sweden)Prognostic Value of O-(2-[18F]Fluoroethyl)-L-Tyrosine PET/CT in Newly Diagnosed WHO 2016 Grade II and III Glioma.
Molecular imaging and biologyPI3K/AKT/mTOR Pathway Alterations Promote Malignant Progression and Xenograft Formation in Oligodendroglial Tumors.
Clinical cancer research : an official journal of the American Association for Cancer ResearchGlioma Simultaneously Present with Adjacent Meningioma: Case Report and Literature Review.
Asian journal of neurosurgeryc-Met Expression Is a Useful Marker for Prognosis Prediction in IDH-Mutant Lower-Grade Gliomas and IDH-Wildtype Glioblastomas.
World neurosurgeryWidely metastatic IDH1-mutant glioblastoma with oligodendroglial features and atypical molecular findings: a case report and review of current challenges in molecular diagnostics.
Diagnostic pathologyPrognostic factors associated with survival in patients with anaplastic oligodendroglioma.
PloS oneInfluence of molecular classification in anaplastic glioma for determining outcome and future approach to management.
Journal of medical imaging and radiation oncologyDetermination of genetic aberrations and novel transcripts involved in the pathogenesis of oligodendroglioma using array comparative genomic hybridization and next generation sequencing.
Oncology lettersAnaplastic Oligodendroglioma Found as an Incidental Photopenic Lesion on 18F-FP-CIT PET/CT Image.
Clinical nuclear medicineSequencing of Chemotherapy and Radiotherapy for Newly Diagnosed Anaplastic Oligodendroglioma and Oligoastrocytoma.
American journal of clinical oncologyAnaplastic oligodendroglioma metastasizing to the bone marrow: a unique case report and literature review.
The International journal of neuroscienceTumour-to-Tumour Metastasis Phenomenon: Metastatic Prostatic Adenocarcinoma within an Anaplastic Oligodendroglioma in the Brain of a Dog.
Journal of comparative pathologyTumour volume reduction following PET guided intensity modulated radiation therapy and temozolomide in IDH mutated anaplastic glioma.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of AustralasiaAnaplastic Glioma: Treatment Approaches in the Era of Molecular Diagnostics.
Current treatment options in oncologyNavigated Transcranial Magnetic Stimulation in Patient with Cranioplasty in Situ: Safe and Accurate Procedure.
World neurosurgeryRadiotherapy plus temozolomide or PCV in patients with anaplastic oligodendroglioma 1p19q codeleted.
Revista de neurologiaMultiple Extraneural Metastases of Anaplastic Oligodendroglioma.
Asian journal of neurosurgerySomatostatin receptor 2A protein expression characterizes anaplastic oligodendrogliomas with favorable outcome.
Acta neuropathologica communicationsAnaplastic oligodendroglioma with leptomeningeal dissemination in a french bulldog.
The Journal of veterinary medical science[Li-Fraumeni syndrome in a patient with multiple anaplastic oligodendrogliomas of the brain (a case report and literature review)].
Zhurnal voprosy neirokhirurgii imeni N. N. BurdenkoGrade II and III Oligodendroglioma and Astrocytoma.
Neurologic clinicsFluorescence-guidance in non-Gadolinium enhancing, but FET-PET positive gliomas.
Clinical neurology and neurosurgeryMachine Learning for Better Prognostic Stratification and Driver Gene Identification Using Somatic Copy Number Variations in Anaplastic Oligodendroglioma.
The oncologistEfficacy of Gamma Knife Radiosurgery for Recurrent High-Grade Gliomas with Limited Tumor Volume.
Journal of Korean Neurosurgical SocietyClinical and Molecular Recursive Partitioning Analysis of High-grade Glioma Treated With IMRT.
American journal of clinical oncologyExpression of Oligodendrocyte Precursor Cell Markers in Canine Oligodendrogliomas.
Veterinary pathologyCytomegalovirus Hemorrhagic Cystitis in a Malignant Glioma Patient Treated with Temozolomide.
Internal medicine (Tokyo, Japan)Staphylococcus epidermidis meningitis in the absence of a neurosurgical device secondary to catheter-related bloodstream infection: a case report and review of the literature.
Journal of medical case reportsReclassification of 400 consecutive glioma cases based on the revised 2016WHO classification.
Brain tumor pathologyClinical significance of the 2016 WHO classification in Japanese patients with gliomas.
Brain tumor pathologyNRG oncology RTOG 9006: a phase III randomized trial of hyperfractionated radiotherapy (RT) and BCNU versus standard RT and BCNU for malignant glioma patients.
Journal of neuro-oncologyRadiographic patterns of recurrence and pathologic correlation in malignant gliomas treated with bevacizumab.
CNS oncologyClinical importance of eflornithine (α-difluoromethylornithine) for the treatment of malignant gliomas.
CNS oncologyRecurrence patterns after maximal surgical resection and postoperative radiotherapy in anaplastic gliomas according to the new 2016 WHO classification.
Scientific reportsA case of radiation-induced osteosarcoma of the skull presenting as a cutaneous epidermotropic tumor with a short latent period.
Journal of cutaneous pathologyRetrospective review of safety and efficacy of programmed cell death-1 inhibitors in refractory high grade gliomas.
Journal for immunotherapy of cancerRechallenge temozolomide in glioma: A case series from India.
Indian journal of cancerA Case of Anaplastic Oligodendroglioma With Extensive Extraneural Metastases Imaged With FDG PET.
Clinical nuclear medicineSEOM clinical guidelines for anaplastic gliomas (2017).
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico[Application of ATRX in diagnosis and prognostic evaluation of glioma].
Zhonghua bing li xue za zhi = Chinese journal of pathologyTargeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma.
NatureReclassification of Mixed Oligoastrocytic Tumors Using a Genetically Integrated Diagnostic Approach.
Journal of pathology and translational medicineThreshold of the extent of resection for WHO Grade III gliomas: retrospective volumetric analysis of 122 cases using intraoperative MRI.
Journal of neurosurgeryRegression of Recurrent High-Grade Glioma with Temozolomide, Dexamethasone, and Levetiracetam: Case Report and Review of the Literature.
World neurosurgeryMultimodal 18F-Fluciclovine PET/MRI and Ultrasound-Guided Neurosurgery of an Anaplastic Oligodendroglioma.
World neurosurgeryA Case of Congenital Brainstem Oligodendroglioma: Pathology Findings and Review of the Literature.
Case reports in neurological medicineComplete durable response of a pediatric anaplastic oligodendroglioma to temozolomide alone: Case report and review of literature.
Pediatric blood & cancerDiffuse Infiltrating Oligodendroglioma and Astrocytoma.
Journal of clinical oncology : official journal of the American Society of Clinical OncologyCerebrospinal fluid dissemination of high-grade gliomas following boron neutron capture therapy occurs more frequently in the small cell subtype of IDH1R132H mutation-negative glioblastoma.
Journal of neuro-oncologyImmunoglobulin D Multiple Myeloma Presenting as Spontaneous Fracture.
Case reports in oncologySome characteristics of gliomas managed at a Neurosurgery centre in Nigeria.
The Nigerian postgraduate medical journalTreatment Outcomes in 1p19q Co-deleted/Partially Deleted Gliomas.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiquesA case series of salvage CCNU in high-grade glioma who have previously received temozolomide from a tertiary care institute in Mumbai.
Indian journal of cancerValue of Minimum Apparent Diffusion Coefficient on Magnetic Resonance Imaging as a Biomarker for Predicting Progression of Disease Following Surgery and Radiotherapy in Glial Tumors from a Tertiary Care Center in Northern India.
Journal of neurosciences in rural practiceMulticenter phase II study of temozolomide and myeloablative chemotherapy with autologous stem cell transplant for newly diagnosed anaplastic oligodendroglioma.
Neuro-oncologyImproving contrast enhancement in magnetic resonance imaging using 5-aminolevulinic acid-induced protoporphyrin IX for high-grade gliomas.
Oncology lettersGenetic landscape of extreme responders with anaplastic oligodendroglioma.
OncotargetRepurposing Mebendazole as a Replacement for Vincristine for the Treatment of Brain Tumors.
Molecular medicine (Cambridge, Mass.)Diffuse leptomeningeal glioneuronal tumor (DLGNT) mimicking Whipple's disease: a case report and literature review.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryBevacizumab for Patients with Recurrent Gliomas Presenting with a Gliomatosis Cerebri Growth Pattern.
International journal of molecular sciencesOutcomes for Anaplastic Glioma Treated With Radiation Therapy With or Without Concurrent Temozolomide.
American journal of clinical oncologyBevacizumab in high-grade glioma patients following intraparenchymal hemorrhage.
Neuro-oncology practiceFeline glioma: a retrospective study and review of the literature.
Journal of feline medicine and surgeryEfficacy of bevacizumab therapy for unresectable malignant glioma: A retrospective analysis.
Molecular and clinical oncologyHistological spectrum of oligodendroglial tumors: Only a subset shows 1p/19q codeletion.
Neurology IndiaEffects of the functional HOTAIR rs920778 and rs12826786 genetic variants in glioma susceptibility and patient prognosis.
Journal of neuro-oncologyRacial disparities in anaplastic oligodendroglioma: An analysis on 1643 patients.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of AustralasiaMolecular characterization reveals NF1 deletions and FGFR1-activating mutations in a pediatric spinal oligodendroglioma.
Pediatric blood & cancerTumor cells with neuronal intermediate progenitor features define a subgroup of 1p/19q co-deleted anaplastic gliomas.
Brain pathology (Zurich, Switzerland)Clinical utility and treatment outcome of comprehensive genomic profiling in high grade glioma patients.
Journal of neuro-oncologyPhase I/II Study of Temozolomide Plus Nimustine Chemotherapy for Recurrent Malignant Gliomas: Kyoto Neuro-oncology Group.
Neurologia medico-chirurgicaExpression profiling of RE1-silencing transcription factor (REST), REST corepressor 1 (RCOR1), and Synapsin 1 (SYN1) genes in human gliomas.
Journal of B.U.ON. : official journal of the Balkan Union of OncologyThe Correlation Between 1p/19q Codeletion, IDH1 Mutation, p53 Overexpression and Their Prognostic Roles in 41 Turkish Anaplastic Oligodendroglioma Patients.
Turkish neurosurgeryCaring for Patients with Newly Diagnosed High-Grade Gliomas.
Seminars in neurologyAssociações
Organizações que acompanham esta doença — pra ter apoio e orientação
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Anesthesia management in a pregnant woman with a giant temporoparietal anaplastic oligodendroglioma: a case report.
- Hematological Malignancies With Multiple Primary Cancers: A Rare Case Presentation.
- Investigation of mismatch repair protein expression in glioma.
- Long-Term Remission of Recurrent Anaplastic Oligodendroglioma With WT-1-Specific CD8+ T-Cell Therapy: A Case Report.
- Do clinical outcomes in individuals with malignant gliomas differ between sexes?
- Adjuvant chemoradiotherapy with procarbazine, lomustine, and vincristine (PCV) or temozolomide for 1p/19q Co-deleted anaplastic oligodendroglioma: a systematic review and network meta-analysis.
- Designing a web-based platform for dynamic estimation of individualized conditional survival in grade 3 gliomas.
- Combined temozolomide, immunotherapy and radiotherapy in a patient with anaplastic oligodendroglioma and multiple extracranial metastases: A rare case report.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:251630(Orphanet)
- MONDO:0016696(MONDO)
- GARD:9472(GARD (NIH))
- Variantes catalogadas(ClinVar)
- Busca completa no PubMed(PubMed)
- Artigo Wikipedia(Wikipedia)
- Q84955701(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
