Development and pilot application of a point-of-need molecular xenomonitoring protocol for tsetse (Glossina sp:) in a low-resource setting.

Dual faces of γδ T cells in trypanosomatid infections.

External quality assessment for yaws elimination in low- and middle-income countries using plasmid-based proficiency test items.

Molecular identification of trypanosome species and vertebrate blood meals in wild tsetse flies from Binoum in the forest area of the littoral region of Cameroon.

Control of Human African Trypanosomiasis in the Nola-Bilolo Focus, Central African Republic, 2020-2024: Outcome of Capacity Building, Improved Diagnosis and Treatment.

Human Leukocyte Antigen-G is enriched in presence of trypanosome in the dermis of individuals exposed to gambiense Human African Trypanosomiasis in Guinea and Côte d'Ivoire.

Harnessing nature: a systematic exploration of in vitro antileishmanial and antihuman African trypanosomal properties in traditional medicinal plants and their active principles.

MALDI-TOF MS identification of Glossina from Senegal and Guinea, and detection of associated Trypanosomes.

Identification of Steroidal Alkaloids with In Vitro Antiprotozoal Activity from Holarrhena pubescens Wall. ex G. Don.

A Novel Cell-Based PCR Method for Accurate Characterization of African Trypanosomes.

Conformational analysis of difluoromethylornithine: factors influencing its gas-phase and bioactive conformations.

Development and validation of a sample-to-result real time multiplex RT-PCR test for human African trypanosomiasis and arboviral febrile illnesses in the Democratic Republic of the Congo.

Glossina from the Republic of the Congo: species identification by MALDI-TOF MS and research of associated micro-organisms.

Roles of cytokines in modulating Trypanosoma brucei rhodesiense infection outcomes in vervet monkeys.

Effects of CYP3A4 variants and drug-drug interactions on the metabolism of fexinidazole.

Modulation of succinyl-CoA:3-ketoacid CoA transferase activity by a single amino acid residue in acetate:succinate CoA transferase from Trypanosoma brucei, the causative agent of African sleeping sickness.

Lipid Metabolism in Insect Vectors of Diseases.

Eliminating human African trypanosomiasis: lessons from Kenya.

Population structure of G. pallidipes tsetse flies in Northwestern Kenya - Towards effective vector control.

Insights from aquaporin structures into drug-resistant sleeping sickness.

Restricted insecticide application: a last mile control option for elimination of acute sleeping sickness and progressive control of African animal trypanosomiasis in South-Eastern Uganda.

Combined toxicity of polyethylene micro/nanoplastics and PFOA in zebrafish (Danio rerio): Impacts on antioxidant, neurotransmission, and gut microbiota.

Unexpected Clinical Drug-Drug Interaction of Fexinidazole on Midazolam Pharmacokinetics: Insights into Underlying Mechanisms from Clinical Phase I Study Results and Supporting In Vivo/Vitro Evidence.

Ecological zonation and phylogeographic structure of Glossina pallidipes (Diptera: Glossinidae) in eastern and southern Africa.

Antiprotozoal Aminosteroid Alkaloids from Buxus obtusifolia (Mildbr.) Hutch.

Evaluation of NTD-O2, a Ghanaian herbal medicine, for onchocerciasis and animal African trypanosomiasis.

Prospective evaluation of 2nd generation rapid diagnostic tests for the serological diagnosis of gambiense human African trypanosomiasis in the Democratic Republic of the Congo.

Measuring elimination of gambiense human African trypanosomiasis: a comparison of deceptively different metrics.

Nitroquinolones and nitroquinolines: syntheses and antitrypanosomal activity.

Novel Cyanotriazole Compounds for Treating Kinetoplastid Diseases, Particularly, Chagas Disease, Leishmaniasis, and Human African Trypanosomiasis.

A CRISPR-based diagnostic tool to survey drug resistance in human African trypanosomiasis.

Structural Basis of Redox-Dependent Affinities of Dihydroorotate Dehydrogenase for Its Substrates and Products.

Potent kinase inhibitors from the Merck KGaA OGHL: Novel hits against Trypanosoma brucei with potential for repurposing.

Patient journeys for neglected tropical diseases in rural sub-Saharan Africa: a scoping review.

Trypanosoma brucei cattle infections contain cryptic transmission-adapted bloodstream forms at low parasitaemia.

Extending Thioflavin T Fluorescence Probe to 2-Ethenyl-benzothiazole Derivatives: Drug-like Quadruplex Ligands with Potent Antitrypanosomatid Activity.

Development of a camelid single-domain antibody-based antigen detection assay for the pan-specific diagnosis of active human and animal Trypanosoma brucei infections.

Genomic Insights into Genetic Diversity and Adaptation of Nanyang Cattle: Implications for Conservation and Breeding.

Fexinidazole results in specific effects on DNA synthesis and DNA damage in the African trypanosome.

Human East African Trypanosomiasis.

Cure of experimental Trypanosoma vivax infection with a single dose of an unmodified antibody-based drug targeting the invariant flagellum cell surface protein IFX.

DNA Vaccine Encoding Trypanosoma brucei MSP-B Elicited IgG and IFN-γ Responses and Partial Protection in Immunised Mice.

Targets of the human antibody response to the variant surface glycoprotein of Trypanosoma brucei.

Passive surveillance of human African trypanosomiasis in the Democratic Republic of the Congo: clinical presentation and prospective evaluation of rapid diagnostic and reference laboratory test accuracy.

Global Epidemiology of Vector-Borne Parasitic Diseases: Burden, Trends, Disparities, and Forecasts (1990-2036).

N-Myristoyltransferase Inhibition in Parasitic Pathogens: Insights from Computer-Aided Drug Design.

Interventions for Neglected Diseases Caused by Kinetoplastid Parasites: A One Health Approach to Drug Discovery, Development, and Deployment.

Thermo-related degeneration of stumpy forms of Trypanosoma brucei, the pathogen of African sleeping sickness.

A SHERLOCK toolbox for eco-epidemiological surveillance of African trypanosomes in domestic pigs from Western Africa.

Mass balance, pharmacokinetics, metabolism, and excretion of radiolabeled acoziborole, a potential novel treatment for human African trypanosomiasis, following single microtracer oral dose to humans.

IL-4Rα signalling influences behavioural and immune responses in Trypanosoma brucei-infected mice: Evidence for iloprost as a neuroprotective agent.

Optimization of Physicochemical Properties and ADME for 2,4-Substituted 1H-Pyrrolo[2,3b]pyridines Inhibitors of Trypanosome Proliferation.

Optimization of Quinazolines for Inhibition of Trypanosoma brucei Proliferation.

Genome-wide overexpression screen reveals a novel transcription termination factor in Trypanosoma brucei.

Molecular docking to homology models of human and Trypanosoma brucei ERK8 that identified ortholog-specific inhibitors.

Human African Trypanosomiasis (HAT): Epidemiology, Biological Diagnosis and Treatment: A Review.

Spatiotemporal changes in prevalence of Sodalis glossinidius, Spiroplasma spp. and trypanosome species in wild Glossina tachinoides from Sora-Mboum animal African trypanosomiasis focus in northern Cameroon.

From pan-active to parasite-selective antiparasitic agents: A scaffold hopping approach.

Pharmacokinetics of Racemic Eflornithine in Human Plasma and Cerebrospinal Fluid: Clinical Perspectives for L-eflornithine Against Human African Trypanosomiasis.

Unlocking the blueprint to eliminating neglected tropical diseases: A review of efforts in 50 countries that have eliminated at least 1 NTD.

Use of fexinidazole in gambiense human African trypanosomiasis: a retrospective analysis of cases treated in Lui Hospital, South Sudan (2018-2024).

Thiazolidinones and related analogues as efficient antitrypanosomal agents.

Controlling rate of release of tsetse fly repellent blend by encapsulating in β-cyclodextrin nanoparticles.

Dermal trypanosomes in seropositive suspects of gambiense human African trypanosomiasis in Côte d'Ivoire.

Indigenous African chickens (Gallus gallus domesticus) lack an anti-Trypanosoma factor and have a prospect for zoonotic transmission of African trypanosomiasis.

The Burden of Neglected Tropical Diseases in Rwanda: A Scoping Review.

Spiroplasma, Wolbachia, Sodalis and trypanosome associations in Glossina Tachinoides from Yankari game reserve, Nigeria.

Telemedicine and human African trypanosomiasis in Angola: Local insights into challenges and opportunities for remote health delivery.

Functional genomics of trypanotolerant and trypanosusceptible cattle infected with Trypanosoma congolense across multiple time points and tissues.

In Vitro Leishmanicidal Efficacy of Synthesized Arylidene Analogues of Glitazone.

A Cell Biologist's View on APOL1: What We Know and What We Still Need to Address.

Key RNA-binding domains in the La protein establish tRNA modification levels in Trypanosoma brucei.

Antiproliferative and Trypanocidal Activity of Ivermectin Bioconjugates.

Role of the nucleotide excision repair endonuclease XPF in the kinetoplastid parasite Trypanosoma brucei.

Synthesis and Combination Studies of Novel Dipeptide Nitriles with Curcumin for a Potent Synergistic Action Against Rhodesain, Cysteine Protease of Trypanosoma brucei rhodesiense.

Discovery of Novel CRK12 Inhibitors for the Treatment of Human African Trypanosomiasis: An Integrated Computational and Experimental Approach.

Detection of antibodies against the African parasite Trypanosoma brucei using synthetic glycosylphosphatidylinositol oligosaccharide fragments.

Chalcogen Derivatives for the Treatment of African Trypanosomiasis: Biological Evaluation of Thio- and Seleno-Semicarbazones and Their Azole Derivatives.

Identification and initial characterisation of Trypanosoma Cox17 copper metallochaperone.

Towards elimination: Challenges in community participation to a gHAT 'screen and treat' strategy using the new oral drug acoziborole in the Democratic Republic of the Congo.

Stumpy forms are the predominant transmissible forms of Trypanosoma brucei.

CryoEM structure of the Trypanosoma brucei flagellum central apparatus.

Syntheses of benzothiazole amidoximes and arylimidamides and evaluation of their ADME and DNA binding properties and activity against Trypanosoma brucei.

Control measures for neglected tropical diseases: vaccine updates.

Chemical and Genetic Validation of an Essential Calcium Entry Channel of Trypanosoma brucei as a Therapeutic Target.

Antitrypanosomal secondary metabolites from medicinal plants: a review.

The "Gredouno" Cross Target: a new tool adapted to control Glossina palpalis gambiensis in the mangrove forests of Guinea.

Modelling motility of Trypanosoma brucei.

Cytological profiling of trypanocidal principles from Aloe barbadensis and Taraxacum officinale.

A cytidine deaminase-like protein modulates pyrimidine nucleotide homeostasis in Trypanosoma brucei.

Recent Progress in Thiazole, Thiosemicarbazone, and Semicarbazone Derivatives as Antiparasitic Agents Against Trypanosomatids and Plasmodium spp.

Restyling an old scaffold: Ebsulfur analogs with improved activity and selectivity against the infective stage of trypanosomes.

Fexinidazole as a new oral treatment for human African trypanosomiasis due to Trypanosoma brucei rhodesiense: a prospective, open-label, single-arm, phase 2-3, non-randomised study.

Effectiveness and safety of fexinidazole for gambiense human African trypanosomiasis and exploration of adherence in outpatients: a phase 3b, prospective, open-label, non-randomised, cohort study.

Fexinidazole for human African trypanosomiasis: the challenge of accessibility.

Potential of entomopathogenic fungi for Glossina austeni control: insights into microbiome alterations and implications on sustainable management of the pest.

High-confidence glycosomal membrane protein inventory unveils trypanosomal peroxin PEX15.

The STROGHAT study protocol: An intervention study to evaluate safety, effectiveness and feasibility of treating gambiense HAT seropositive subjects with acoziborole.

The extracellular region of Trypanosoma congolense Membrane Bound Acid Phosphatase induces partial protection in immunized BALB/c mice.

The impact of canine African trypanosomiasis in anti-poaching dogs in the Republic of Zambia.

Notes from the Field: Rhodesiense Human African Trypanosomiasis (Sleeping Sickness) in a Traveler Returning from Zimbabwe - United States, August 2024.

Production of Protease Inhibitor With Penicillium sp. - Optimization of the Medium for Growth in Pellet Form and Cytotoxicity Testing.

Anti-Trypanosomatid and Antiplasmodial Activities of Alkaloids From Hippeastrum Species.

Human African trypanosomiasis.

Antiprotozoal Aminosteroids from Pachysandra terminalis.

Development and Assessment of a Multiple-Analysis System for Diagnosing Malaria and Other Blood Parasite Infections in Humans and Non-Human Primates.

Evaluation of the AnTat A/B and LiTat A/B primers for the detection of Trypanosoma bruceigambiense.

Heterocyclic core modifications in trypanosomacidal 2-[(phenylheteroaryl)ethyl]ureas.

Bold strides towards the elimination of gambiense human African trypanosomiasis (gHAT) as a public health problem-A case study of Angola.

Identification of Substituted 4-Aminocinnolines as Broad-Spectrum Antiparasitic Agents.

Zinc from an Essential Element to an Antiparasitic Therapeutic Agent.

Toward the elimination of HAT in Nigeria: leaving no community behind.

Deep mutational scanning of the Trypanosoma brucei developmental regulator RBP6 reveals an essential disordered region influenced by positive residues.

Shrinking the lymphatic filariasis map of Zimbabwe: Reassessing the population requiring treatment through confirmatory mapping.

Uncovering the Mechanism of Action of Antiprotozoal Agents: A Survey on Photoaffinity Labeling Strategy.

Isolation and Total Synthesis of Ukabamide, an Antitrypanosomal Lipopeptide from a Marine Moorena sp. Cyanobacterium.

Identification of serum biomarkers and therapeutic targets for aortic diseases in obesity through multi-omics analysis.

Manipulation of mitochondrial poly(A) polymerase family proteins in Trypanosoma brucei impacts mRNA termini processing.

A murine model of Trypanosoma brucei-induced myocarditis and cardiac dysfunction.

Understanding Sex-biases in Kinetoplastid Infections: Leishmaniasis and Trypanosomiasis.

Transforming the chemotherapy of human African trypanosomiasis.

Dynamic changes of gut microbiota between the first and second trimester for women with gestational diabetes mellitus and their correlations with BMI: a nested cohort study in China.

Dual suppression of Glossina pallidipes using entomopathogenic fungal-based biopesticides and sterile insect technique.

Retrospective clinical performance evaluation of the Abbott Bioline HAT 2.0, a rapid diagnostic test for human African trypanosomiasis based on recombinant antigens.

Discovery and Development of an Advanced Lead for the Treatment of African Trypanosomiasis.

Therapeutic effects and mechanisms of berberine on enteritis caused by Salmonella in poultry.

Prevalence and attributable health burdens of vector-borne parasitic infectious diseases of poverty, 1990-2021: findings from the Global Burden of Disease Study 2021.

Phytochemical Analysis, Cytotoxicity, and Antitrypanosomal, Antioxidant, and Anti-Inflammatory Activities of Clausena anisata Fruit, Azadirachta indica Leaf, and Stem Bark Extracts.

G1 and G2 variants of apolipoprotein L1 among Central African population in Trypanosoma brucei gambiense endemic rural area.

Carmaphycin B-Based Proteasome Inhibitors to Treat Human African Trypanosomiasis: Structure-Activity Relationship and In Vivo Efficacy.

Rearing of Glossina morsitans morsitans tsetse flies for the sterile insect technique: evaluating the impact of irradiation and transportation during early and late-stage pupal development on the quality of emerging adults.

The cost of sleeping sickness vector control in Yasa Bonga, a health district in the Democratic Republic of the Congo.

Dynamic composition of stress granules in Trypanosoma brucei.

Insights into trypanosomiasis transmission: Age, infection rates, and bloodmeal analysis of Glossina fuscipes fuscipes in N.W. Uganda.

Impact of a national tsetse control programme to eliminate Gambian sleeping sickness in Uganda: a spatiotemporal modelling study.

An evaluation of African animal trypanosomiasis control strategies in remote communities of Eastern Zambia.

A loop-mediated isothermal amplification test for yaws: a multi-country diagnostic accuracy evaluation.

New WHO guidelines for treating rhodesiense human African trypanosomiasis: expanded indications for fexinidazole and pentamidine.

Biogenesis of EVs in Trypanosomatids.

An integrated active case detection and management of skin NTDs in yaws endemic health districts in Cameroon, Côte d'Ivoire and Ghana.

Trypanocide Use and Molecular Characterization of Trypanosomes Resistant to Diminazene Aceturate in Cattle in Northern Côte D'Ivoire.

Diversity of trypanosomes in tsetse fly caught in two "silent" sleeping sickness foci of Bafia and the Manoka Island in Cameroon.

Advancing age grading techniques for Glossina morsitans morsitans, vectors of African trypanosomiasis, through mid-infrared spectroscopy and machine learning.

Free Radical Production Induced by Nitroimidazole Compounds Lead to Cell Death in Leishmania infantum Amastigotes.

Domestic dogs as reservoirs for African trypanosomiasis in Mambwe district, eastern Zambia.

To Explore Potential Natural Inhibitors of Cysteine Proteases to Combat Human African Trypanosomiasis and Chagas Disease.

Cholesterol Efflux Decreases TLR4-Target Gene Expression in Cultured Macrophages Exposed to T. brucei Ghosts.

Neglected Tropical Diseases: A Chemoinformatics Approach for the Use of Biodiversity in Anti-Trypanosomatid Drug Discovery.

Prevalence of dermal trypanosomes in suspected and confirmed cases of gambiense human African trypanosomiasis in Guinea.

Pharmacophore Identification and Structure-Activity Relationship Analysis of a Series of Substituted Azaindoles as Inhibitors of Trypanosoma brucei.

Caught in a trap: DNA contamination in tsetse xenomonitoring can lead to over-estimates of Trypanosoma brucei infection.

Modelling timelines to elimination of sleeping sickness in the Democratic Republic of Congo, accounting for possible cryptic human and animal transmission.

Pass the boron: benzoxaboroles as antiparasite drugs.

The comprehensive epidemiological status of human African trypanosomiasis in Nigeria: meta-analysis and systematic review of the full story (1962-2022).

Advancement in the development of DNA vaccines against Trypanosoma brucei and future perspective.

Trypanosoma brucei multi-aminoacyl-tRNA synthetase complex formation limits promiscuous tRNA proofreading.

Evaluation of ITS1 rDNA primers for the detection and identification of African trypanosomes in mammalian hosts and tsetse flies.

The activities of suaveolol and other compounds from Hyptis suaveolens and Momordica charantia against the aetiological agents of African trypanosomiasis, leishmaniasis and malaria.

Evaluation of the International Task Force for Disease Eradication: A Review of Past Deliberations.

Cardiac involvement in Chagas disease and African trypanosomiasis.

Imaging Assays to Detect DNA Damage in Trypanosome Parasites Using γH2A.

Unexpected discovery of Trypanosoma brucei gambiense on CSF in a western country: About a case.

Specificity of serological screening tests and reference laboratory tests to diagnose gambiense human African trypanosomiasis: a prospective clinical performance study.

Integrated proteomic and metabolomic profiling reveals novel insights on the inflammation and immune response in HFpEF.

A Nanobody/Monoclonal Antibody "hybrid" sandwich technology offers an improved immunoassay strategy for detection of African trypanosome infections.

Human African Trypanosomiasis (Sleeping Sickness)-Epidemiology, Clinical Manifestations, Diagnosis, Treatment, and Prevention.

State-of-the-art clinical update on African trypanosomiasis.

Knowledge, attitudes and practices towards yaws in endemic areas of Ghana, Cameroon and Côte d'Ivoire.

Demystifying In Vivo Bioluminescence Imaging of a Chagas Disease Mouse Model for Drug Efficacy Studies.

Multifunctional Organometallic Compounds Active against Infective Trypanosomes: Ru(II) Ferrocenyl Derivatives with Two Different Bioactive Ligands.

[Updating the northern tsetse distribution limit in Chad in the context of global change].

Novel 4-[4-(4-methylpiperazin-1-yl)phenyl]-6-arylpyrimidine derivatives and their antitrypanosomal activities against T.brucei.

Targeting Trypanothione Metabolism in Trypanosomatids.

Synthesis and biological evaluation of orally active anti-Trypanosoma agents.

Eflornithine for treatment of high-risk neuroblastoma.

From pole to pole, life-long research of sleep in extreme environments.

Adipose and skin distribution of African trypanosomes in natural animal infections.

Designing Antitrypanosomal and Antileishmanial BODIPY Derivatives: A Computational and In Vitro Assessment.

Discovery of 1,3,4-Oxadiazole Derivatives as Broad-Spectrum Antiparasitic Agents.

How are Trypanosoma brucei receptors protected from host antibody-mediated attack?

Comparison of Three Widely Employed Extraction Methods for Metabolomic Analysis of Trypanosoma brucei.

The Transmission of Animal African Trypanosomiasis in Two Districts in the Forest Zone of Ghana.

Anogeissus leiocarpus (DC.) Guill. & Perr. (Combretaceae): A review of the traditional uses, phytochemistry and pharmacology of African birch.

Elimination of human African trypanosomiasis: The long last mile.

To Explore Potential Inhibitors against Various Enzymatic Targets of Human African Trypanosomiasis.

Development of Novel Peptidyl Nitriles Targeting Rhodesain and Falcipain-2 for the Treatment of Sleeping Sickness and Malaria.

Discovery of Strong 3-Nitro-2-Phenyl-2H-Chromene Analogues as Antitrypanosomal Agents and Inhibitors of Trypanosoma cruzi Glucokinase.

Using Passive Surveillance to Maintain Elimination as a Public Health Problem for Neglected Tropical Diseases: A Model-Based Exploration.

Privileged small molecules against neglected tropical diseases: A perspective from structure activity relationships.

The elimination of human African trypanosomiasis: Monitoring progress towards the 2021-2030 WHO road map targets.

Ginkgo biloba attenuated detrimental inflammatory and oxidative events due to Trypanosoma brucei rhodesiense in mice treated with melarsoprol.

Antiprotozoal Activity of Plants Used in the Management of Sleeping Sickness in Angola and Bioactivity-Guided Fractionation of Brasenia schreberi J.F.Gmel and Nymphaea lotus L. Active against T. b. rhodesiense.

The internal transcribed spacer 1 sequence polymorphism brings updates to tsetse species distribution in the northern Cameroon: Importance in planning efficient vector control.

Comparison of stochastic and deterministic models for gambiense sleeping sickness at different spatial scales: A health area analysis in the DRC.

An In vitro and in silico investigation of the antitrypanosomal activities of the stem bark extracts of Anopyxis klaineana (Pierre) Engl.

Study on the underlying molecular mechanism of benzene-induced nervous system damage in mice based on tandem mass tag (TMT) proteomics.

Identification of transport systems involved in eflornithine delivery across the blood-brain barrier.

Limited impact of vector control on the population genetic structure of Glossina fuscipes fuscipes from the sleeping sickness focus of Maro, Chad.