Doença oftalmológica rara caracterizada por lesões coriorretinianas pontilhadas do pólo posterior tipicamente bilaterais, assimétricas, amareladas, formando um padrão de ramificação linear e progredindo para cicatrizes atróficas. Membranas neovasculares sub-retinianas ocorrem na maioria dos casos. Vitritis está sempre ausente. Os doentes podem apresentar visão turva, escotoma, moscas volantes, fotopsia e metamorfopsia. A formação da membrana neovascular coroidal e a fibrose sub-retiniana são as principais causas da perda visual. A condição ocorre predominantemente em mulheres jovens com miopia.
Introdução
O que você precisa saber de cara
Doença oftalmológica rara caracterizada por lesões coriorretinianas pontilhadas do pólo posterior tipicamente bilaterais, assimétricas, amareladas, formando um padrão de ramificação linear e progredindo para cicatrizes atróficas. Membranas neovasculares sub-retinianas ocorrem na maioria dos casos. A vitrite está sempre ausente. Os pacientes podem apresentar visão turva, escotoma, moscas volantes, fotopsia e metamorfopsia. A formação da membrana neovascular coroidal e da fibrose sub-retiniana são as principais causas da perda visual. Uma condição ocorre predominantemente em mulheres jovens com miopia.
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
1/2k
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O que aparece no corpo e com que frequência cada sintoma acontece
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🇧🇷 Atendimento SUS — Coroidopatia interna punctiforme
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Publicações mais relevantes
Choroidal neovascularization secondary to punctate inner choroidopathy after resolution of multiple evanescent white dot syndrome: A case report.
White dot syndromes include multiple evanescent white dot syndrome (MEWDS) and punctate inner choroidopathy (PIC), which are rarely reported to coexist or occur sequentially in a single eye. The co-occurrence increases diagnostic complexity, and there are no previous reports of choroidal neovascularization (CNV) secondary to PIC following the resolution of MEWDS. This case report aims to supplement clinical evidence for the pathogenesis and treatment of such sequential ocular diseases. A 42-year-old healthy female presented with blurred vision in her right eye for 3 days initially; 2 months later, her right eye vision worsened further, and 2.5 months after that, she developed blurred vision again with decreased visual acuity. At the first visit, the patient was diagnosed with MEWDS in her right eye based on fundus examination, fundus autofluorescence, fundus fluorescein angiography, visual field test, and optical coherence tomography (OCT) findings. Two months later, she was diagnosed with PIC in the same eye due to new peripapillary yellow-white lesions and corresponding OCT changes. Another 2.5 months later, she was diagnosed with CNV secondary to PIC based on subretinal hemorrhage, abnormal vascular flow on OCT angiography, and fundus fluorescein angiography confirmation. No treatment was given at the initial diagnosis of MEWDS. After the diagnosis of PIC, the patient received oral prednisone (1 mg/kg per day for 5 days, followed by gradual reduction over 6-8 weeks). For CNV secondary to PIC, intravitreal anti-vascular endothelial growth factor (VEGF) therapy (Ranibizumab, 0.5 mg/0.1 mL, once a month, twice in total) was administered. After 2 intravitreal anti-VEGF injections, the best-corrected visual acuity of the patient's right eye improved to 20/20, fundic hemorrhage resolved, and OCT demonstrated complete resolution of CNV. During 2 years of follow-up, no recurrence of CNV or PIC was observed, and best-corrected visual acuity remained stable at 20/20. MEWDS and PIC may share common etiological and pathogenetic mechanisms. PIC may develop sequentially after MEWDS in the same eye, and CNV may be a complication of PIC. A combination of oral corticosteroid therapy for PIC and timely intravitreal anti-VEGF injections for secondary CNV can achieve favorable long-term clinical outcomes. Regular follow-up is necessary for patients with MEWDS to monitor for potential progression to PIC and CNV.
Progressive development of dome-shaped macula and subsequent onset of punctate inner choroidopathy in a highly myopic patient: a 7-year follow-up case report.
To describe the development of dome-shaped macula (DSM) in a highly myopic patient, followed by the subsequent onset of punctate inner choroidopathy (PIC). A 46-year-old man with high myopia, with a systemic history of psoriatic arthritis and an ocular history of Acanthamoeba keratitis resulted in two penetrating keratoplasties (PK) in his right eye, was followed up regularly at our center for a 7-year period. During the follow-up, the left eye remained stable until the fifth year. However, at the seventh year, a routine fundus examination revealed the asymptomatic appearance of lacquer cracks, which had been absent at baseline. Multimodal imaging evaluation further identified the incidental development of a horizontal oriented DSM and active and inactive PIC foci localized near the newly detected lacquer cracks. This case report provides new insights into the formation of DSM, supporting the hypothesis that macular bulge may result from differential elongation of the peri-dome region. Additionally, it highlights that DSM can coexist with PIC.
ROLE OF INFLAMMATION IN ATROPHY DEVELOPMENT AND PROGRESSION IN PATHOLOGIC MYOPIA.
To describe the progression of atrophy in pathologic myopia eyes with prior retinal inflammatory lesions consistent with punctate inner choroidopathy. Retrospective case series of 21 eyes with pathologic myopia and resolved retinal inflammatory lesions compared with 26 noninflamed controls (14 fellow eyes; 12 external myopic eyes with pre-existing patchy atrophy). The primary outcome was annual atrophy-area change (mm2/year) on multimodal imaging. Secondary outcomes included incident/enlarging atrophy, multifocal versus unifocal appearance, and META-PM category progression. Group comparisons used Welch t tests and Fisher exact tests; an age-adjusted linear regression examined independent associations. Over 5.2 ± 3.2 years in inflamed eyes and 5.3 ± 2.4 years in controls, patchy atrophy progressed faster with inflammation (0.76 ± 0.67 vs. 0.38 ± 0.47 mm2/year; P = 0.03). Among eyes starting in myopic macular degeneration Category 1 to 2, incident atrophy occurred in 14 of 14 (100%) inflamed versus 4 of 11 (36.4%) controls (P < 0.01). Overall atrophy activity (new or enlarging) was 21 of 21 (100%) in inflamed eyes versus 19 of 26 (73.1%) controls (P < 0.01). Multifocal atrophy was more frequent with inflammation (15/21, 71.4%) than in controls (6/26, 23.1%; P < 0.01). In age-adjusted regression, inflammation remained independently associated with faster atrophy expansion (β = 0.41 mm2/year; 95% CI, 0.04-0.78; P = 0.033). In pathologic myopia, prior retinal inflammation is independently associated with more frequent multifocal involvement, higher risk of incident atrophy, and a substantially faster atrophy-expansion. Beyond mechanical factors, inflammation seems to be a key driver of atrophic progression in this population.
Revisiting pathologic myopia: imaging evidence of an inflammatory component in the pathogenesis of myopic degeneration.
Pathologic myopia has traditionally been viewed as a degenerative disorder caused by mechanical stretching and choroidal ischemia. However, converging clinical, molecular, and imaging data increasingly suggest that chronic low-grade inflammation contributes to both the onset and progression of myopic retinal degeneration. Recent studies have identified inflammatory patterns-including multifocal choroiditis/punctate inner choroidopathy (MFC/PIC)-like lesions, periatrophic inflammatory "plumes," and secondary Multiple Evanescent White Dots Syndrome (MEWDS)-often localized at sites of retinal pigment epithelium-Bruch's membrane disruption. Parallel laboratory evidence indicates dysregulation of cytokines, activation of the complement cascade, and engagement of intracellular signaling pathways such as JAK-STAT within the myopic eye. Together, these findings support a model in which mechanical stress and hypoxia act as triggers for sustained immune activation, promoting extracellular-matrix remodeling, choroidal thinning, and progressive atrophy. Recognizing inflammation as an integral component of the pathophysiology of pathologic myopia may open new therapeutic perspectives, including immunomodulatory or complement-targeting approaches.
Sex-Related Effects on the Clinical Presentation of Uveitis.
The primary aim of this study was to determine sex-related patterns of uveitic entities. Secondary aims included sex-related patterns of uveitic complications. Retrospective clinical cohort study. 5703 participants presenting with uveitis from January 2009 to December 2023 were included. uveitis entities and complications. 2870 (50.3%) participants were female and 2831 (49.6%) were male. Males presented at a significantly younger age than females (42.2 vs 45.0). Significant sex-based differences were observed in the prevalence of specific uveitic conditions. Females were more likely to develop multifocal choroiditis (female: male ratio 1.818:1), Vogt-Koyanagi-Harada syndrome (female: male ratio 2.136:1), birdshot chorioretinopathy (female: male ratio 2.800:1, punctate inner choroidopathy (female: male ratio 6.571:1), drug-induced uveitis (female: male ratio 2.833:1), Crohn's disease (female: male ratio 3.714:1) and multiple evanescent white dot syndrome (female: male ratio 5.000:1). In contrast, males were more likely to develop acute posterior multifocal placoid pigment epitheliopathy (female: male ratio 0.364:1), sympathetic ophthalmia (female: male ratio 0.353:1) and syphilis (female: male ratio 0.404:1). Cataract was significantly more common in females, and this remained significant after adjusting for age at presentation, anatomical location and bilaterality. Cystoid macular edema and epiretinal membrane were more frequent in females, whereas retinal detachment occurred more often in males. Bilateral vision loss occurred in 238 patients (4.2%) and was significantly more common in females (4.9% vs 3.5%). Sex appears to be a key factor influencing the underlying etiology and clinical course of uveitis. These findings underscore the importance of considering sex as a biological variable in the diagnosis, monitoring, and management of uveitis.
Publicações recentes
MEWDS-like Presentation Unmasking Sequential Bilateral Multifocal Choroiditis: Insights from Longitudinal Multimodal Imaging.
Choroidal neovascularization secondary to punctate inner choroidopathy after resolution of multiple evanescent white dot syndrome: A case report.
Progressive development of dome-shaped macula and subsequent onset of punctate inner choroidopathy in a highly myopic patient: a 7-year follow-up case report.
ROLE OF INFLAMMATION IN ATROPHY DEVELOPMENT AND PROGRESSION IN PATHOLOGIC MYOPIA.
Revisiting pathologic myopia: imaging evidence of an inflammatory component in the pathogenesis of myopic degeneration.
📚 EuropePMC142 artigos no totalmostrando 133
Choroidal neovascularization secondary to punctate inner choroidopathy after resolution of multiple evanescent white dot syndrome: A case report.
MedicineProgressive development of dome-shaped macula and subsequent onset of punctate inner choroidopathy in a highly myopic patient: a 7-year follow-up case report.
American journal of ophthalmology case reportsROLE OF INFLAMMATION IN ATROPHY DEVELOPMENT AND PROGRESSION IN PATHOLOGIC MYOPIA.
Retina (Philadelphia, Pa.)Revisiting pathologic myopia: imaging evidence of an inflammatory component in the pathogenesis of myopic degeneration.
Frontiers in medicineSex-Related Effects on the Clinical Presentation of Uveitis.
American journal of ophthalmologyEn Face Optical Coherence Tomography and OCT Angiography in the Pathoanatomy of Inflammatory Macular Disease.
American journal of ophthalmologyDifferences in epiretinal macrophage-like cells and associated retinochoroidal changes between multifocal choroiditis and punctate inner choroidopathy observed using widefield optical coherence tomography angiography.
Photodiagnosis and photodynamic therapyNear-Infrared Autofluorescence in Non-Infectious Uveitis: A Review.
Ocular immunology and inflammationRetinal phlebitis complicated by punctate inner choroidopathy-like lesions: a case report.
American journal of ophthalmology case reportsIdiopathic Multifocal Choroiditis/Punctate Inner Choroidopathy as a Secondary Inflammatory Reaction to Lacquer Cracks: A Structural and Temporal Analysis.
American journal of ophthalmologyPunctate Inner Choroidopathy Complicated by Multifocal Neovascularization and Schlaegel Lines.
Retina (Philadelphia, Pa.)Macular Complications Predict Visual Decline in Punctate Inner Choroidopathy.
OphthalmologyAI-Driven Optical Coherence Tomography Biomarkers for Choroidal Neovascularization Assessment in Punctate Inner Choroidopathy and Multifocal Choroiditis.
American journal of ophthalmologyMinimum Imaging Sets for Diagnosis, Activity Assessment, and Complications in Noninfectious Posterior Uveitis - Multimodal Imaging in Uveitis (MUV) Task Force Report 9.
American journal of ophthalmologyNoninfectious Uveitis Syndromes.
Advances in experimental medicine and biologySystemic Immunosuppression and Secondary Choroidal Neovascularisation in Patients with Punctate Inner Chorioretinopathy.
Ocular immunology and inflammationPunctate Inner Pachychoroidopathy Associated with Choroidal Neovascularization. A Case Report.
Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnostiSystematic Review of Clinical Utility of Multimodal Imaging in Noninfectious Posterior Uveitis: MUV Project Report 3.
American journal of ophthalmologyPrevalence and clinical characteristics of ocular sarcoidosis among non-infectious uveitis in a Chinese tertiary ophthalmic center: a retrospective observational study.
BMC ophthalmologyLong-term prognosis of punctate inner choroidopathy lesions in pathologic myopia and their relationship to lacquer cracks.
Scientific reportsChoroidal Hyperreflective Foci Represent a Common Finding Across Different Types of Macular Atrophy.
Investigative ophthalmology & visual scienceChoroidal neovascularization secondary to punctate inner choroidopathy vs myopia: clinical outcomes after 1-year of treatment.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle OphthalmologiePUNCTATE INNER CHOROIDOPATHY-LIKE REACTION IN STAGE 3 EXTENSIVE MACULAR ATROPHY WITH PSEUDODRUSEN-LIKE APPEARANCE.
Retinal cases & brief reportsAn update of multimodal imaging in white dot syndrome.
Oman journal of ophthalmologyInfrared Autofluorescence to Identify Activity in Punctate Inner Choroidopathy.
Ophthalmic surgery, lasers & imaging retinaAtypical choroidal neovascular membrane.
American journal of ophthalmology case reports91-month follow-up of solitary punctate chorioretinitis in a Chinese patient.
BMC ophthalmologyPUNCTATE INNER CHOROIDOPATHY AFTER PARS PLANA VITRECTOMY FOR HIGH MYOPIC FULL-THICKNESS MACULAR HOLE.
Retinal cases & brief reportsEXPLORING THE CHALLENGES OF DISTINGUISHING PUNCTATE INNER CHOROIDOPATHY FROM MULTIFOCAL CHOROIDITIS AND PANUVEITIS.
Retina (Philadelphia, Pa.)Schlaegel Lines 360 Degrees in Punctate Inner Choroidopathy.
Ophthalmology. RetinaRecurrent Choroidal Neovascular Membrane as the Initial Presentation of Mycobacterium chimaera-Associated Serpiginoid Choroiditis.
Ocular immunology and inflammationPunctate Inner Choroidopathy (PIC) disease recurrence with inflammatory choroidal neovascular membrane (iCNVM) post-COVID-19 vaccine.
European journal of ophthalmologyClinical features and possible pathogenesis of multiple evanescent white dot syndrome with different retinal diseases and events: a narrative review.
International journal of ophthalmologyDiagnostic Challenges in Inflammatory Choroidal Neovascularization.
Medicina (Kaunas, Lithuania)White Dot Syndromes: Report of Three Cases.
Case reports in ophthalmologyChorioretinopathy Post COVID-19: A Systematic Review and Prevalence Assessment, Unveiling Insights into an Emerging Ocular Entity.
Seminars in ophthalmologySEVERE RECURRENCE AND RETINAL INFLAMMATORY INFILTRATION AFTER CESSATION OF IMMUNOSUPPRESSION FOR MULTIFOCAL CHOROIDITIS AND PANUVEITIS.
Retinal cases & brief reportsPunctate inner choroidopathy: A review of the current diagnostic and therapeutic approaches.
Progress in retinal and eye researchThe multimodal imaging features and outcomes of multifocal choroiditis/punctate inner choroidopathy lesion with multiple evanescent white dot syndrome-like features: a retrospective study.
BMC ophthalmologyDifferential diagnosis of myopic choroidal neovascularization (mCNV): insights from multimodal imaging and treatment implications.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle OphthalmologieTRANSDIFFERENTIATION AND INTRACHOROIDAL MIGRATION OF MELANOTIC RETINAL PIGMENT EPITHELIUM IN PUNCTATE INNER CHOROIDITIS.
Retinal cases & brief reportsPUNCTATE INNER PACHYCHOROIDOPATHY: Demographic and Clinical Features of Inner Choroidal Inflammation in Eyes with Pachychoroid Disease.
Retina (Philadelphia, Pa.)Punctate inner choroidopathy in common variable immunodeficiency associated with a pathogenic variant in the tumour necrosis factor receptor superfamily 13b (TNFRSF13B) gene - Case report and review of the literature.
Clinical immunology (Orlando, Fla.)SOLITARY PUNCTATE CHORIORETINITIS: A Unique Subtype of Punctate Inner Choroidopathy.
Retina (Philadelphia, Pa.)Challenges in posterior uveitis-tips and tricks for the retina specialist.
Journal of ophthalmic inflammation and infectionLatest advances in white spot syndromes: New findings and interpretations.
Progress in retinal and eye researchAssociation of Risk Variants in the CFH Gene With Elevated Levels of Coagulation and Complement Factors in Idiopathic Multifocal Choroiditis.
JAMA ophthalmologyPRIMARY MULTIPLE EVANESCENT WHITE DOT SYNDROME AND MULTIPLE EVANESCENT WHITE DOT SYNDROME SECONDARY TO MULTIFOCAL CHOROIDITIS/PUNCTATE INNER CHOROIDOPATHY: A Comparative Study.
Retina (Philadelphia, Pa.)Corticosteroids Decrease the Incidence and Activity of Choroidal Neovascularization in Patients with Punctuate Inner Choroidopathy or Multifocal Choroiditis.
Ocular immunology and inflammationRECURRENCE OF ACUTE RETINOPATHY IN PSEUDOXANTHOMA ELASTICUM.
Retinal cases & brief reportsAdalimumab Biosimilar-Induced Autoimmunity-Related Sweet-Like Neutrophilic Dermatosis.
The American Journal of dermatopathologySimilarities in the histological mouse model of early herpes simplex retinopathy with punctate inner choroidopathy and Ebola virus disease retinopathy.
European journal of ophthalmologyMULTIMODAL IMAGING OF MULTIFOCAL CHOROIDITIS WITH ADAPTIVE OPTICS OPHTHALMOSCOPY.
Retinal cases & brief reportsPUNCTATE INNER CHOROIDOPATHY-LIKE REACTIONS IN UNRELATED RETINAL DISEASES.
Retina (Philadelphia, Pa.)Outcomes in PIC-Related CNV: Pooled Analysis of Individual Participant Data.
Ocular immunology and inflammationSpectrally resolved autofluorescence imaging in posterior uveitis.
Scientific reportsIdiopathic Multifocal Choroiditis and Punctate Inner Choroidopathy - Evaluation of Risk Factors for Increased Relapse Rate: A 2-Year Prospective Observational Cohort Study.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur AugenheilkundePunctate inner choroidopathy immediately after COVID-19 infection: a case report.
BMC ophthalmologyMultimodal imaging of multiple areas of choroidal neovascularization in punctate inner choroidopathy.
Journal francais d'ophtalmologieKey Multimodal Fundus Imaging Findings to Recognize Multifocal Choroiditis in Patients With Pathological Myopia.
Frontiers in medicineROLE OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN DETECTING AND MONITORING INFLAMMATORY CHOROIDAL NEOVASCULARIZATION.
Retina (Philadelphia, Pa.)Optical Coherence Tomography Findings of Underlying Choroidal Neovascularization in Punctate Inner Choroidopathy.
Frontiers in medicineOutcomes of adalimumab therapy in refractory punctate inner choroidopathy and multifocal choroiditis.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle OphthalmologiePREVALENCE AND CHARACTERISTICS OF MULTIFOCAL CHOROIDITIS/PUNCTATE INNER CHOROIDOPATHY IN PATHOLOGIC MYOPIA EYES WITH PATCHY ATROPHY.
Retina (Philadelphia, Pa.)RPE disruption and hyper-transmission are early signs of secondary CNV with punctate inner choroidopathy in structure-OCT.
BMC ophthalmologyCentral Multifocal Choroiditis: Platelet Granularity as a Potential Marker for Treatment With Steroid-Sparing Immunomodulatory Therapy.
Frontiers in ophthalmologyCORRELATION BETWEEN FOCAL CHOROIDAL EXCAVATION AND UNDERLYING RETINOCHOROIDAL DISEASE: A Pathological Hypothesis From Clinical Observation.
Retina (Philadelphia, Pa.)Inflammatory Choroidal Neovascular Membranes: Clinical Profile, Treatment Effectiveness, and Visual Prognosis.
Journal of ophthalmologyDistinct Patterns of Choroidal Lesions in Punctate Inner Choroidopathy and Multifocal Choroiditis Determined by Heatmap Analysis.
Ocular immunology and inflammationPunctate inner choroidopathy reactivation following COVID-19: A case report.
European journal of ophthalmologyMultifocal Evanescent White Dot Syndrome-like Phenotypes Associated with Inflammatory and Myopic Choroidal Neovascularization.
Ocular immunology and inflammationIdiopathic multifocal choroiditis and punctate inner choroidopathy: an evaluation in pregnancy.
Acta ophthalmologicaSwept Source-Optical Coherence Tomography Angiography for Management of Secondary Choroidal Neovascularization in Punctate Inner Choroidopathy.
Case reports in ophthalmologyChorioretinal Atrophy in Punctate Inner Choroidopathy/multifocal Choroiditis: A Five-year Follow-up Study.
Ocular immunology and inflammationPunctate inner choroidopathy with atypical presentation.
Arquivos brasileiros de oftalmologiaUse of Short-wave Blue Fundus Autofluorescence to Detect and Monitor Acute Regional Outer Retinopathy in Punctate Inner Choroidopathy.
Ocular immunology and inflammationOCTA versus dye angiography for the diagnosis and evaluation of neovascularisation in punctate inner choroidopathy.
The British journal of ophthalmologyPatchy hyperautofluorescence as a predictive factor for the recurrence of punctate inner choroidopathy.
Photodiagnosis and photodynamic therapyCharacteristics of punctate inner choroidopathy complicated by choroidal neovascularisation on Multispectral Imaging in comparison with other imaging modalities.
Ocular immunology and inflammationMultiple Evanescent White Dot Syndrome Presenting in a Patient With Punctate Inner Choroidopathy.
Journal of vitreoretinal diseasesEfficacy and safety of certolizumab pegol in pregnant women with uveitis. Recommendations on the management with immunosuppressive and biologic therapies in uveitis during pregnancy.
Clinical and experimental rheumatologyOccult inflammation detected by autofluorescence May Be the cause of idiopathic choroidal neovascularization.
American journal of ophthalmology case reportsRapid and spontaneous resolution of hemorrhagic macular hole retinal detachment and subretinal hemorrhages in an eye with pathologic myopia: a case report.
BMC ophthalmologyDistribution and Progression of Inflammatory Chorioretinal Lesions Related to Multifocal Choroiditis and Their Correlations with Clinical Outcomes at 24 Months.
Ocular immunology and inflammationMerging Information From Infrared and Autofluorescence Fundus Images for Monitoring of Chorioretinal Atrophic Lesions.
Translational vision science & technologyDIFFERENTIAL RESPONSE TO GLUCOCORTICOID IMMUNOSUPPRESSION OF TWO DISTINCT INFLAMMATORY SIGNS ASSOCIATED WITH PUNCTATE INNER CHOROIDOPATHY.
Retina (Philadelphia, Pa.)[Choroidal neovascularization due to a punctate inner choroidopathy visualized by optical coherence tomography angiography].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen GesellschaftThe "Sponge sign": A novel feature of inflammatory choroidal neovascularization.
European journal of ophthalmologyOptical Coherence Tomography Angiography Changes in Choroidal Vasculature following Treatment in Punctate Inner Choroidopathy.
Ocular immunology and inflammationDifferentiating Multifocal Choroiditis and Punctate Inner Choroidopathy: A Cluster Analysis Approach.
American journal of ophthalmologyPresence or absence of choroidal hyper-transmission by SD-OCT imaging distinguishes inflammatory from neovascular lesions in myopic eyes.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle OphthalmologieLong-term Outcome of Zonal Outer Retinopathy in Punctate Inner Choroidopathy or Multifocal Choroiditis.
Ocular immunology and inflammation[White dot syndromes : Principles, diagnostics, and treatment].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen GesellschaftUsing optical coherence tomography angiography to guide the treatment of pathological myopic patients with submacular hemorrhage.
Photodiagnosis and photodynamic therapyIntraretinal Cystoid Spaces in Regression of Punctate Inner Choroidopathy Lesions.
Ocular immunology and inflammationTwo-Year Outcome of Aflibercept for the Treatment of Choroidal Neovascularization in Punctate Inner Choroidopathy.
Case reports in ophthalmologyLong-Term Outcome of Punctate Inner Choroidopathy or Multifocal Choroiditis with Active Choroidal Neovascularization Managed with Intravitreal Bevacizumab.
Ocular immunology and inflammationPunctate Inner Choroidopathy and Choroidal Neovascularization in Korean Patients.
Ocular immunology and inflammationDevelopment of Secondary Choroidal Neovascularization in Focal Choroidal Excavation of Punctate Inner Choroidopathy.
Ocular immunology and inflammationImmunosuppressants and/or antivascular endothelial growth factor inhibitors in punctate inner choroidopathy? Follow-up results with optical coherence tomography angiography.
The British journal of ophthalmologyTreatment of Punctate Inner Choroidopathy with Choroidal Neovascularization Using Corticosteroid and Intravitreal Ranibizumab.
BioMed research internationalAn update on inflammatory choroidal neovascularization: epidemiology, multimodal imaging, and management.
Journal of ophthalmic inflammation and infectionEtiologies and Characteristics of Choroidal Neovascularization in Young Chinese Patients.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur AugenheilkundeLong-term results of intravitreal bevacizumab and dexamethasone for the treatment of punctate inner choroidopathy associated with choroidal neovascularization: A case series.
SAGE open medical case reportsOptical coherence tomography angiography in comparison with other multimodal imaging techniques in punctate inner choroidopathy.
The British journal of ophthalmologyOptical Coherence Tomography Angiography of Punctate Inner Choroidopathy.
Case reports in ophthalmological medicineOptical Coherence Tomography Angiography Findings in Punctate Inner Choroidopathy.
Ophthalmic surgery, lasers & imaging retinaRisk Factors for Developing Choroidal Neovascular Membrane and Visual Loss in Punctate Inner Choroidopathy.
OphthalmologyEfficacy and safety of conbercept as a primary treatment for choroidal neovascularization secondary to punctate inner choroidopathy.
BMC ophthalmologyInflammatory choroidal neovascularization in Indian eyes: Etiology, clinical features, and outcomes to anti-vascular endothelial growth factor.
Indian journal of ophthalmologyIntravitreal anti-VEGF treatment for choroidal neovascularization secondary to punctate inner choroidopathy.
International ophthalmologyMulti-modal imaging and anatomic classification of the white dot syndromes.
International journal of retina and vitreousHow to Differentiate Myopic Choroidal Neovascularization, Idiopathic Multifocal Choroiditis, and Punctate Inner Choroidopathy Using Clinical and Multimodal Imaging Findings.
Ophthalmic surgery, lasers & imaging retinaObservation and Clinical Pattern in Patients with White Dot Syndromes: The Role of Color Photography in Monitoring Ocular Changes in Long-Term Observation.
Medical science monitor : international medical journal of experimental and clinical researchIdiopathic Multifocal Choroiditis.
Journal of ophthalmic & vision researchOptical Coherence Tomography Angiography for Detecting Choroidal Neovascularization Secondary to Punctate Inner Choroidopathy.
Ophthalmic surgery, lasers & imaging retinaPunctate inner choroidopathy: A review.
Survey of ophthalmologyCombined treatment in punctate inner choroidopathy.
Therapeutics and clinical risk managementPunctate inner choroidopathy complicated with exudative neurosensory detachment: A favourable response to treatment with systemic corticosteroids and intravitreal ranibizumab.
Archivos de la Sociedad Espanola de OftalmologiaChoroidal neovascularisation on optical coherence tomography angiography in punctate inner choroidopathy and multifocal choroiditis.
The British journal of ophthalmologyEtiology and treatment of choroidal neovascularization in pediatric patients.
European journal of ophthalmology[Punctate Inner Choroidopathy].
Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnostiAdjunctive use of systematic retinal thickness map analysis to monitor disease activity in punctate inner choroidopathy.
Journal of ophthalmic inflammation and infectionChoroidal Neovascularization Associated with Punctate Inner Choroidopathy: Combination of Intravitreal Anti-VEGF and Systemic Immunosuppressive Therapy.
Case reports in ophthalmologyOPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY AND WIDEFIELD FUNDUS AUTOFLUORESCENCE IN PUNCTATE INNER CHOROIDOPATHY.
Retinal cases & brief reportsThe Fundus Autofluorescence Spectrum of Punctate Inner Choroidopathy.
Journal of ophthalmologyClinical Characteristics of Inflammatory Choroidal Neovascularization in a Chinese Population.
Ocular immunology and inflammationPunctate Inner Choroidopathy.
Case reports in ophthalmological medicineClinical characteristics and antivascular endothelial growth factor effect of choroidal neovascularization in younger patients in Taiwan.
Taiwan journal of ophthalmologyPunctate inner choroidopathy: a systematic review.
Medical hypothesis, discovery & innovation ophthalmology journalFocal Choroidal Excavation in Multifocal Choroiditis and Punctate Inner Choroidopathy.
OphthalmologyPunctate inner choroidopathy in systemic lupus.
Journal francais d'ophtalmologieSpectral-domain optical coherence tomographic features of choroidal neovascular membranes in multifocal choroiditis and punctate inner choroidopathy.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle OphthalmologieAssociações
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Choroidal neovascularization secondary to punctate inner choroidopathy after resolution of multiple evanescent white dot syndrome: A case report.
- Progressive development of dome-shaped macula and subsequent onset of punctate inner choroidopathy in a highly myopic patient: a 7-year follow-up case report.
- ROLE OF INFLAMMATION IN ATROPHY DEVELOPMENT AND PROGRESSION IN PATHOLOGIC MYOPIA.
- Revisiting pathologic myopia: imaging evidence of an inflammatory component in the pathogenesis of myopic degeneration.
- Sex-Related Effects on the Clinical Presentation of Uveitis.
- MEWDS-like Presentation Unmasking Sequential Bilateral Multifocal Choroiditis: Insights from Longitudinal Multimodal Imaging.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:580951(Orphanet)
- MONDO:0035584(MONDO)
- GARD:7503(GARD (NIH))
- Busca completa no PubMed(PubMed)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
