外阴-阴道-牙龈综合征（VVGS）是一种罕见的扁平苔藓亚型，累及外阴、阴道和牙龈多部位黏膜，常表现为伴有糜烂的疼痛性红斑病变，可导致器官结构和功能不可逆转的损害。本文报道1例累及多器官并伴有复杂全身情况的VVGS患者的诊疗过程，旨在提高口腔医师对VVGS的认知，助力提高多学科联合早期诊断和治疗VVGS的水平。本病例经过多学科联合诊治，通过局部治疗联合全身用药7个月，获得了良好的治疗效果。.

Lichen planus (LP) is a chronic inflammatory disorder primarily affecting the skin and mucous membranes, characterized by pruritic, violaceous papules often exhibiting a polygonal pattern. This dermatological disorder can affect various sites of the body, including the skin, nails, hair, and mucous membranes out of which the oral mucosa is the most commonly affected. We report a case of a 40-year-old female with a unique combination of cutaneous, nail, and mucosal LP manifestations coexisting with lichen planopilaris and vulvovaginal-gingival syndrome.

In order to retrospectively analyse the multi-site involvement pattern of erosive lichen planus patients, we retrospectively reported the clinical and medical data of three patients with erosive lichen planus which involving their vulva, vagina, gingiva, and ear canal. We confirmed the existence of otic lichen planus, and found that it is more common in patients with vulvovaginal-gingival syndrome of erosive lichen planus. Therefore, we propose 'vulvovaginal-gingival-otic syndrome' to further describe this rare compound pattern of lichen planus.

Oral Lichen Planus (OLP) is a chronic inflammatory disease of skin and mucous membranes. Approximately 20% of women with oral lichen planus develops lesions in the genital mucosa. In 1982, Pelisse described a special form of lichen planus (LP), which consists of a triad of symptoms: vulval, vaginal and gingival (VVG)-LP lesions. Aim of the present report is to report two new cases and review the international literature. Two cases of VVG-LP are reported and a review of recent literature is performed. The onset of erosive or ulcerative mouth lesions may precede or follow by months or even years the onset of vulvovaginal lesions. Vaginal agglutination is associated with the postmenopausal state in conjunction with a dermatologic condition. Intra-lesional corticosteroids have a role in localized chronic ulceration, while systemic therapies such as corticosteroids, azathioprine, mycophenolate mofetil, hydroxychloroquine, ciclosporin, methotrexate, retinoids, thalidomide and photo chemotherapy have been used in more severe cases with varying success. VVG-LP is rather a rare condition and has been documented in the literature mainly in the form of case reports. Lack of a precise diagnostic criteria of VVG-LP depends on the specialists.