Introdução
O que você precisa saber de cara
Epiblefaro é uma condição caracterizada por uma prega horizontal congênita de pele próxima à margem da pálpebra superior ou inferior, causada pela inserção anômala de fibras musculares. Essa prega extra de pele redireciona os cílios para uma posição vertical, onde eles podem entrar em contato com o globo ocular, afetando a córnea ou a conjuntiva. É mais comumente encontrado em indivíduos asiáticos, especialmente crianças. Uma estimativa aponta que a porcentagem de crianças asiáticas afetadas com idade entre 7 e 14 anos é de 12,6%.
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Entender a doença
Do básico ao detalhe, leia no seu ritmo
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Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Linha do tempo da pesquisa
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Genética e causas
O que está alterado no DNA e como passa nas famílias
Nenhum gene associado encontrado
Os dados genéticos desta condição ainda estão sendo catalogados.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Epiblefaron
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Ensaios clínicos abertos e novidades científicas recentes
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Pesquisa e ensaios clínicos
1 ensaios clínicos encontrados.
Publicações mais relevantes
Impact of simultaneous eyelid and exotropia surgery on the surgical outcomes of pediatric patients with intermittent exotropia: a retrospective observational study.
This study aimed to compare the surgical outcomes of pediatric patients with intermittent exotropia who underwent simultaneous eyelid and exotropia surgery and those who underwent exotropia surgery alone. The medical records of patients aged <18 years who underwent surgery for intermittent exotropia were retrospectively reviewed. The patients were grouped according to whether they underwent simultaneous eyelid surgery. In the simultaneous surgery group, the association between clinical factors, including the type of eyelid procedure, and surgical success was also analyzed. A favorable outcome was defined as an ocular alignment of ≤10 prism diopters (PD) for exodeviation and ≤4 PD for esodeviation at the final follow-up. This study included 118 patients, of whom 31 underwent simultaneous eyelid and exotropia surgery and 87 underwent exotropia surgery alone. Bilateral repair of lower eyelid epiblepharon was the most common eyelid procedure (27/31, 87.1%). Success rates did not differ significantly between the two groups (log-rank test, p=0.291). In the simultaneous surgery group, no clinical factors, including the type of eyelid surgery, were significantly associated with favorable outcomes (all p>0.05). Simultaneous eyelid and exotropia surgery produced surgical outcomes comparable to those of exotropia surgery alone, validating the safety and feasibility of the combined procedure in appropriately selected pediatric patients.
Surgical Correction for Pediatric Epiblepharon and Trichiasis.
Lower eyelid epiblepharon is a condition that is common in Asian children and improves with age in most patients; however, the problem can persist until school age or even adulthood. No difference has been observed in terms of incidence in association with sex or the affected eye, and the condition mainly affects the lower eyelid, usually in both eyes. The condition typically features horizontal semilunar skin folds lying parallel to the palpebral margin that accumulate and push the eyelashes towards the ocular surface, which rub against the cornea, resulting in corneal injury and irritation symptoms that affect the daily life of the child. Surgery remains the currently preferred method for alleviating corneal irritation symptoms. Although diverse surgical procedures are available in terms of clinical practice, the modified Hotz procedure remains the most widely used. The surgical procedure primarily focuses on two key aspects: the precise determination of the amount of skin to be removed and improving the tightness between the palpebral retractor aponeurosis and the anterior layer of the eyelid. In this study, lower eyelid epiblepharon is categorized into three distinct types based on the affected area: medial lower eyelid epiblepharon (affecting the medial skin of the lower eyelid); central epiblepharon (involving half of the lower eyelid); and total involvement Type A epiblepharon (involving the full-length of the eyelid). The surgical approach was tailored according to classification, with Type A cases receiving L-shaped excisions and Types B and C crescent-shaped incisions. The postoperative outcomes were evaluated to determine the cure rate. Most patients experienced mild postoperative reactions, and no obvious sunken scars or double lower eyelids were observed. Satisfactory results were thus obtained with mild postoperative reactions.
Surgical management of patients with corneal lesions due to lid pathologies.
The surgical management of corneal lesions resulting from eyelid pathologies requires a comprehensive approach to ensure optimal patient outcomes. Eyelid lesions, ranging from benign to malignant, can lead to corneal damage through mechanisms such as mechanical abrasion, secondary infection, or inflammatory responses. To assess the surgical methodologies utilized in the treatment of corneal lesions resulting from eyelid disorders and evaluate their effects on patient outcomes, recurrence rates, and postoperative complications. The incorporation of advanced imaging techniques, including optical coherence tomography and ultrasound biomicroscopy, in conjunction with histopathological analysis, is addressed to improve surgical accuracy and patient outcomes. The authors searched online databases (PubMed and Cochrane) for publications on the surgical management of lid lesions. Records received from the two databases were checked for duplicates and relevance. Only records with full texts and in English language were included. A total of 28 records were obtained following the screening for relevancy and duplication. The review underscores essential surgical approaches employed in the treatment of corneal lesions resulting from common eyelid diseases, focusing on operative efficacy, complication rates, and long-term results. This systematic review emphasizes the significance of choosing suitable surgical techniques tailored to individual patient characteristics and stresses the need for interdisciplinary collaboration in ophthalmic care. The results indicate that sophisticated imaging techniques and careful preoperative preparation markedly improve surgical accuracy and long-term results.
Evaluation of epicanthoplasty for child epiblepharon.
Epiblepharon is a common disease in Asian children. It may cause astigmatism and amblyopia; hence, some cases require surgical treatment. Although the modified Hotz procedure is a common surgery, some cases of recurrence have been reported. One of the causes is the presence of the epicanthal fold. In this study, we retrospectively investigated the applicability of epicanthoplasty for epiblepharon in children based on the severity of the epicanthal fold. Patients under 13 years of age were evaluated to determine whether the modified Hotz procedure should be combined with epicanthoplasty based on the severity of epicanthal fold and rates of recurrence. The severity of the epicanthal fold was classified into 3 levels (mild, moderate, and severe) according to Wang's classification based on the degree of epicanthal fold covering the lacrimal caruncle. A total of 58 eyes were investigated with a mean age of 7.6 (4-13) years. The mean observation period was 11 (6-30) months. Thirty patients underwent the modified Hotz procedure alone and it was combined with epicanthoplasty in 28 patients. Although there were no differences in the recurrence rate between the mild and moderate cases, the recurrence rate in the group that underwent the modified Hotz procedure combined with epicanthoplasty was significantly lower than the group that underwent the modified Hotz procedure alone for the severe cases (0% vs. 33.3%). Therefore, it is suggested that the classification of epicanthal fold severity is useful for determining the surgical procedure, and that epicanthoplasty is necessary only in severe pediatric cases.
Modified Lower Eyelid Retractor Relocation: A More Reliable Surgical Approach for Epiblepharon.
Epiblepharon is a congenital anatopism characterized by a horizontal skinfold near the eyelid margin, causing corneal irritation and damage. Standard surgical management occasionally results in undercorrection and relatively high recurrence. In addition, a pronounced postoperative lower eyelid crease can be an unfavorable cosmetic alteration, particularly for Asian patients. This work describes a new surgical technique to reduce recurrence rates while improving cosmetic and functional outcomes for epiblepharon. Thirty-nine patients (75 eyelids) underwent epiblepharon surgery from January 2021 to April 2023. Their mean age was 15.0 years with a mean follow-up period of 16.5 months. Surgically, the lower eyelid retractors (LERs) were fully exposed and detached from the inferior tarsus margin and conjunctiva. The free LERs were sutured directly to the marginal orbicularis oculi muscle, maintaining flexible mobility to the LERs without standard anchoring to the tarsus margin. All 39 patients achieved complete eversion of the cilia without cornea contact by the final follow-up. Of the 75 eyelids, 70 (93%) demonstrated a "good" outcome, 5 (7%) had a "fair" outcome, and none were classified as "poor." Mean margin-to-reflex distance 2 remained statistically unchanged between preoperative and postoperative measurements. Our new surgical method provides satisfactory functional and cosmetic results, reducing recurrence rates and minimizing the risk of excessive lower eyelid crease, ectropion, and severe hypertrophic scarring. The method offers a reliable alternative, particularly for Asian patients, who typically have less pronounced eyelid creases.
Publicações recentes
The Correlation Between Epiblepharon and Obesity in Pediatric Patients: A Retrospective Comparative Study.
Impact of simultaneous eyelid and exotropia surgery on the surgical outcomes of pediatric patients with intermittent exotropia: a retrospective observational study.
Surgical Correction for Pediatric Epiblepharon and Trichiasis.
Surgical management of patients with corneal lesions due to lid pathologies.
Evaluation of epicanthoplasty for child epiblepharon.
📚 EuropePMC135 artigos no totalmostrando 81
Impact of simultaneous eyelid and exotropia surgery on the surgical outcomes of pediatric patients with intermittent exotropia: a retrospective observational study.
Journal of Yeungnam medical scienceSurgical Correction for Pediatric Epiblepharon and Trichiasis.
Journal of visualized experiments : JoVESurgical management of patients with corneal lesions due to lid pathologies.
World journal of clinical casesEvaluation of epicanthoplasty for child epiblepharon.
Journal of plastic, reconstructive & aesthetic surgery : JPRASModified Lower Eyelid Retractor Relocation: A More Reliable Surgical Approach for Epiblepharon.
Plastic and reconstructive surgery. Global openThe effects of lower eyelid epiblepharon surgery on the meibomian glands.
BMC ophthalmologyCorneal Topographic Changes Due to Pediatric Epiblepharon Surgery.
Clinical ophthalmology (Auckland, N.Z.)Management of Eyelid Pathologies That Cause Corneal Lesions.
Advances in experimental medicine and biologyA Comparison between 2-Octyl Cyanoacrylate and Conventional Suturing for the Closure of Epiblepharon Incision Wounds in Children: A Retrospective Case-Control Study.
Journal of clinical medicineCongenital epiblepharon in Chinese school-age children: a cross-sectional study.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and StrabismusMorphological and functional characteristics of the meibomian gland in pediatric patients with epiblepharon.
BMC ophthalmologySensory Function of Children With Strabismus After Epiblepharon Surgery.
Journal of pediatric ophthalmology and strabismusEyelid Surgery in Thyroid Eye Disease.
Ophthalmic plastic and reconstructive surgeryRotating suture technique combined with lid margin split and lower eyelid retractor disinsertion for epiblepharon.
Journal of plastic, reconstructive & aesthetic surgery : JPRASOrbicularis muscle fixation downward for the correction of congenital epiblepharon in Chinese patients.
Journal of plastic, reconstructive & aesthetic surgery : JPRASComparing the effectiveness of two surgical techniques for treating lower lid epiblepharon in children: a randomized controlled trial.
Scientific reportsDouble Eyelid Blepharoplasty, Epicanthoplasty, and Epiblepharon Correction in Improving Postoperative Eyelid Esthetics: A Retrospective Study of 27 Chinese Patients.
Journal of plastic, reconstructive & aesthetic surgery : JPRASMinimal lower eyelid epicanthoplasty combined with thermal contraction to treat epiblepharon in chinese children.
BMC ophthalmologySevere corneal involvement secondary to congenital lower eyelid epiblepharon.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle OphthalmologieUnusual presentation of infectious crystalline keratopathy: A case report with literature review.
European journal of ophthalmologySex-Specific Effect of Obesity on Epiblepharon in Different Age Groups: A Case-Control Study.
International journal of environmental research and public healthA Case of Clinically Atypical Gelatinous Drop-like Corneal Dystrophy With Unilateral Recurrent Amyloid Depositions.
CorneaAnalysis of Changes in High-order Aberration and Contrast Sensitivity After Epiblepharon Surgery.
Ophthalmic plastic and reconstructive surgeryModified Epiblepharon Repair Preserving Orbicularis Oculi Muscle.
Journal of ophthalmologyPrevalence of ophthalmological manifestations in pediatric and adolescent populations with Down syndrome: a systematic review of the literature.
Systematic reviewsChanges in Direction of Eyelashes After Epiblepharon Surgery Using the Hotz Procedure.
The Journal of craniofacial surgeryOutcomes of surgery for epiblepharon accompanied with lower eyelid retraction secondary to buphthalmos in children.
Pediatric investigationHigh-frequency radio wave electrocautery in modified Hotz operations for epiblepharon correction.
BMC ophthalmologyAdjustable Medial Epicanthoplasty Using a Rotational Flap for Epiblepharon Repair.
The Journal of craniofacial surgerySurgical Correction of Lower Lid Epiblepharon With Skin-Only Resection Using a Novel Design.
The Journal of craniofacial surgeryHigh Therapeutic and Esthetic Properties of Extracellular Vesicles Produced from the Stem Cells and Their Spheroids Cultured from Ocular Surgery-Derived Waste Orbicularis Oculi Muscle Tissues.
Antioxidants (Basel, Switzerland)Morphological changes after lower eyelid epiblepharon surgery in Asian children.
BMC ophthalmologyAcquired Epiblepharon Alleviated With Teprotumumab Treatment in Active Thyroid Eye Disease Patient.
Ophthalmic plastic and reconstructive surgeryComparison of ocular axis and corneal diameter between entropion and non-entropion eyes in children with congenital glaucoma.
World journal of clinical casesEpiblepharon in a Case of Anterior Megalophthalmos: A Diagnostic Red Herring.
CureusSkin redraping for correction of lower eyelid epiblepharon combined with medial epicanthal fold: a retrospective analysis of 286 Asian children.
Eye (London, England)Change in the eye position under general anesthesia in children with intermittent exotropia.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and StrabismusSurgical correction of recurrent epiblepharon in Chinese children using modified skin re-draping epicanthoplasty.
International journal of ophthalmologyGene expression profiles of pro-inflammatory mediators in the conjunctiva of patients with epiblepharon.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle OphthalmologieSurgical Treatment of Epiblepharon Effectively Alleviates Keratopathy but Not Astigmatism: A Case-Control Study Utilizing Vector Analysis in East Asian Children.
Journal of ophthalmologyThe prevalence of lower eyelid epiblepharon and its association with refractive errors in Chinese preschool children: a cross-sectional study.
BMC ophthalmologyCause analysis and reoperation effect of failure and recurrence after epiblepharon correction in children.
World journal of clinical casesEffect of Congenital Lower Eyelid Epiblepharon Surgery on Asymmetric Margin Reflex Distance 1.
Current eye researchThe association between epiblepharon and obesity: an experience at tertiary care center in Western Pennsylvania/North America.
International ophthalmologyOphthalmic Abnormalities among Children Treated with Cochlear Implants.
The journal of international advanced otologyA retrospective study of pediatric thyroid eye disease: the Asian experience.
Orbit (Amsterdam, Netherlands)Analysis of corneal real astigmatism and high order aberration changes that cause visual disturbances after lower eyelid epiblepharon repair surgery.
Scientific reportsPostoperative Quality of Life in Oculoplastic Patients.
Ophthalmic plastic and reconstructive surgeryRelationship Between Visual Acuity and Corneal Curvature Change in Children After Epiblepharon Surgery.
The Journal of craniofacial surgeryCharacterization of the Upper Tarsal Plate Growth in Children: Implication in Pediatric Eyelid Surgery.
The Journal of craniofacial surgeryReduction in Recurrence Rate by Combining Modified Hotz Procedure With Epicanthoplasty to Treat Congenital Epiblepharon.
Annals of plastic surgeryThyroid Eye Disease-Related Epiblepharon: A Comparative Case Study.
Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)Treatment of symptomatic epiblepharon with Botulinum toxin type A in patients under 2years of age.
Archivos de la Sociedad Espanola de OftalmologiaModified Hotz procedure with CO2 laser ablation of the orbicularis oculi muscle for epiblepharon.
Canadian journal of ophthalmology. Journal canadien d'ophtalmologieReporting outcomes of hyaluronic gel filler as a treatment for epiblepharon.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle OphthalmologieSex-specific difference in age distribution of congenital lower eyelid epiblepharon in a Japanese population.
Japanese journal of ophthalmologyEpiblepharon correction in Korean children based on the epicanthal pathology.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle OphthalmologieLower eyelid tension balance reconstruction: A new procedure for the repair of congenital epiblepharon with epicanthus.
Journal of plastic, reconstructive & aesthetic surgery : JPRASEpiblepharon outcomes: comparing apples and oranges.
The British journal of ophthalmologyUpper Arch Flap Combined with Extended Incision of Lower Eyelid: A Modified Epicanthoplasty in Correcting Epicanthus.
Aesthetic plastic surgeryUse of the Bispectral Index to Predict Eye Position of Children during General Anesthesia.
Korean journal of ophthalmology : KJOTransient bilateral epiblepharon occurring during pregnancy.
Clinical & experimental ophthalmologyNonsurgical correction of epiblepharon using hyaluronic acid gel.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and StrabismusModified everting sutures: an alternative treatment for mild to moderate epiblepharon.
The British journal of ophthalmologyNon-incisional eyelid everting suture technique for treating lower lid epiblepharon.
The British journal of ophthalmologyChanges in Corneal Curvature After Epiblepharon Surgery in Children.
The Journal of craniofacial surgeryRelationship between lower eyelid epiblepharon and epicanthus in Korean children.
PloS oneEpiblepharon in congenital glaucoma: case-control study.
The British journal of ophthalmologyConservative Management of Lower Eyelid Epiblepharon in Children.
Journal of pediatric ophthalmology and strabismusAssociation Between Head Tilt and Asymmetric Epiblepharon.
JAMA ophthalmologyManagement of epiblepharon: state of the art.
Current opinion in ophthalmologyBlepharoplasty with a Buried Double Twisted Suture Technique to Correct Upper Eyelid Epiblepharon.
Plastic and reconstructive surgery. Global openConjunctival myxoma - atypical presentation of a rare tumour: case report and review of literature.
BMC ophthalmologyEffects of epiblepharon surgery on higher-order aberrations.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and StrabismusState of the Art in Congenital Eyelid Deformity Management.
Facial plastic surgery : FPSEpiblepharon in Chinese children: relationships with body mass index and surgical treatment.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and StrabismusModified Hotz Procedure Combined With Modified Z-Epicanthoplasty Versus Modified Hotz Procedure Alone for Epiblepharon Repair.
Ophthalmic plastic and reconstructive surgerySecondary localized corneal amyloidosis caused by lower eyelid epiblepharon.
Canadian journal of ophthalmology. Journal canadien d'ophtalmologieA Review of Eyelid Margin Malpositions: A Unique Spectrum in a South-East Asian Tertiary Hospital.
Ophthalmic plastic and reconstructive surgeryOphthalmic manifestations in children and young adults with Down syndrome and congenital heart defects.
Ophthalmic epidemiologyEpiblepharon-induced head tilt masquerading as torticollis.
Ophthalmic plastic and reconstructive surgeryAssociações
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Impact of simultaneous eyelid and exotropia surgery on the surgical outcomes of pediatric patients with intermittent exotropia: a retrospective observational study.
- Surgical Correction for Pediatric Epiblepharon and Trichiasis.
- Surgical management of patients with corneal lesions due to lid pathologies.
- Evaluation of epicanthoplasty for child epiblepharon.
- Modified Lower Eyelid Retractor Relocation: A More Reliable Surgical Approach for Epiblepharon.
- The Correlation Between Epiblepharon and Obesity in Pediatric Patients: A Retrospective Comparative Study.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:99169(Orphanet)
- MONDO:0020461(MONDO)
- GARD:19671(GARD (NIH))
- Busca completa no PubMed(PubMed)
- Q3726816(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
