Raras
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Aneurisma do septo auricular
ORPHA:99107CID-10 · Q21.1CID-11 · LA8E.YDOENÇA RARA

A síndrome de Loeys-Dietz (SLD) é uma doença genética autossômica dominante que afeta o tecido conjuntivo. Apresenta características semelhantes à síndrome de Marfan e à síndrome de Ehlers-Danlos. A doença é caracterizada por aneurismas na aorta, frequentemente em crianças, e a aorta também pode sofrer dissecção súbita nas camadas enfraquecidas da parede da aorta. Aneurismas e dissecções também podem ocorrer em artérias além da aorta.

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Introdução

O que você precisa saber de cara

📋

Aneurisma do septo interatrial é uma protusão anormal do septo interatrial, podendo estar associado a defeitos cardíacos congênitos. Geralmente assintomático, pode raramente causar arritmias ou embolia.

Publicações científicas
895 artigos
Último publicado: 2026 Apr
🏥
SUS: Cobertura mínimaScore: 20%
Triagem neonatal (Fase 5)CID-10: Q21.1
🇧🇷Dados SUS / DATASUS
PROCEDIMENTOS SIGTAP (5)
0202010503
Cariótipo — bandas G, Q ou Rgenetic_test
0202010600
Pesquisa de microdeleções/microduplicações por FISHlab_test
0202010694
Sequenciamento completo do exoma (WES)rehabilitation
0202010260
Dosagem de alfa-fetoproteína
0301070040
Atendimento em reabilitação — doenças raras
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Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

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Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico895PubMed
Últimos 10 anos200publicações
Pico202032 papers
Linha do tempo
2026Hoje · 2026🧪 2007Primeiro ensaio clínico📈 2020Ano de pico
Publicações por ano (últimos 10 anos)

Triagem neonatal (Teste do Pezinho)

👶
Teste: qPCR para deleção de SMN1 em sangue seco
Fase 5 do PNTNpending
Incidência no Brasil: 1:10.000

A triagem neonatal permite diagnóstico precoce e início imediato do tratamento.

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Genética e causas

O que está alterado no DNA e como passa nas famílias

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Nenhum gene associado encontrado

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3Fase 31
·Pré-clínico2
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 3 ensaios
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Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Aneurisma do septo auricular

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Ensaios clínicos abertos e novidades científicas recentes

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4 ensaios clínicos encontrados.

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Publicações mais relevantes

Timeline de publicações
289 papers (10 anos)
#1

[A case of cryptogenic stroke with platypnea-orthodeoxia syndrome and paroxysmal atrial fibrillation].

Rinsho shinkeigaku = Clinical neurology2026 Feb 05

The patient was a 72-year-old man who presented to our hospital with gait disturbance. He had sustained a spinal fracture one year earlier. Neurological examination revealed left-sided hemiparesis, dysarthria, and a National Institutes of Health Stroke Scale (NIHSS) score of 3. Brain MRI demonstrated cortical infarctions in both cerebral hemispheres. Transesophageal echocardiography revealed a grade 3 patent foramen ovale (PFO) accompanied by an atrial septal aneurysm. He exhibited hypoxemia in the upright position, which improved when supine, leading to a diagnosis of platypnea-orthodeoxia syndrome (POS). He underwent percutaneous PFO closure and was subsequently discharged home. Fifteen weeks after surgery, left-sided paralysis was observed, and paroxysmal atrial fibrillation was detected, leading to a diagnosis of cardioembolic stroke. A PFO, which had been asymptomatic, contributed to the development of POS due to its impact on thoracic compression fractures and atherosclerosis. In the care of elderly patients, the coexistence of multiple conditions is not uncommon, necessitating careful interpretation of test results.

#2

Percutaneous Patent Foramen Ovale Closure and Aneurysm Elimination by Direct Suture.

JACC. Case reports2026 Mar 18

Patent foramen ovale (PFO) with significant atrial septal aneurysm (ASA) may pose technical challenges. In selected cases, direct-suture closure may represent an effective alternative to close the PFO and reduce aneurysmal redundancy. A 54-year-old woman with recurrent transient ischemic episodes and hyperintensity changes on magnetic resonance imaging was referred for percutaneous PFO closure. Transesophageal echocardiography demonstrated right-to-left shunt and markedly aneurysmal interatrial septum with constant rightward displacement. Under echocardiographic guidance, the septum was displaced leftward using a transseptal sheath, allowing wire passage. The PFO was subsequently closed with direct sutures, eliminating the ASA by creating a loop on the right atrial side. Direct-suture closure can be considered even in the presence of large ASA, as it not only allows effective PFO closure but also reduction of aneurysmal redundancy. Direct-suture percutaneous PFO closure can successfully and safely be performed in patients with ASA.

#3

Correlation Between Patent Foramen Ovale Morphological Characteristics and Right-to-Left Shunt Severity in Stroke Patients with High RoPE Scores.

Cerebrovascular diseases (Basel, Switzerland)2026 Mar 17

To evaluate the association between Risk of Paradoxical Embolism (RoPE) score, patent foramen ovale (PFO) morphological characteristics, and right-to-left shunt severity in ischemic stroke patients with high RoPE scores. In this prospective observational study, 162 ischemic stroke patients with confirmed PFO and RoPE scores ≥7 were enrolled. All patients underwent contrast-enhanced transcranial Doppler, transthoracic echocardiography, and transesophageal echocardiography. PFO morphology (size, tunnel length, atrial septal aneurysm, Eustachian valve, Chiari network) and shunt severity were assessed. Associations between RoPE score, its components, and PFO characteristics were analyzed. Patients with higher RoPE scores (9-10) showed a greater prevalence of complex PFO than those with scores of 7-8 (71.2% vs. 45.4%, p<0.001). RoPE score independently predicted complex PFO morphology (adjusted OR 2.48, 95% CI 1.68-3.67). Younger age and absence of hypertension were the strongest contributing factors. RoPE score correlated positively with shunt severity (ρ=0.58, p<0.001), with severe shunting more frequent in patients with higher scores. Higher RoPE scores are strongly associated with complex PFO anatomy and severe right-to-left shunting. Integrating detailed PFO assessment with clinical risk stratification may improve individualized management of PFO-associated stroke.

#4

Platypnea-orthodeoxia syndrome treated by percutaneous patent foramen ovale closure: a case report and review of the literature.

Journal of medical case reports2026 Mar 05

Platypnea-orthodeoxia syndrome is a rare but striking clinical syndrome, usually characterized by dyspnea and hypoxemia in the upright position, which is relieved by recumbency. However, the exact prevalence remains unknown. Patent foramen ovale is most commonly associated with this syndrome. Although patent foramen ovale is a common condition, the incidence of platypnea-orthodeoxia syndrome in patients with patent foramen ovale is relatively low. Here, we report a case of a 68-year-old Chinese man with platypnea-orthodeoxia syndrome due to patent foramen ovale without pulmonary hypertension who was successfully treated with transcatheter closure. A 68-year-old Chinese man presented to the emergency department with acute-onset dyspnea and hypoxemia without significant precipitating factors. Tachycardia and tachypnea were observed after the initial assessment. Transthoracic echocardiography revealed an enlarged aortic root (42 mm), mild aortic valve regurgitation, and impaired left ventricular diastolic function. No significant additional findings were observed. The patient was subsequently admitted to the Respiratory Medicine Department for further investigation. Comprehensive clinical and laboratory reevaluations revealed postural hypoxemia and dyspnea. Arterial blood gases in the upright and supine positions were as follows: partial pressure of arterial oxygen = 33/69 mmHg, partial pressure of arterial carbon dioxide = 17/22 mmHg, pH = 7.54/7.48, HCO3- = 14.5/16.4 mmol/L, and arterial oxygen saturation = 73/95% (1 minute after stopping oxygen supplementation), suggesting a provisional diagnosis of platypnea-orthodeoxia syndrome. Further evaluation using transesophageal echocardiography identified patent foramen ovale. Agitated saline transthoracic echocardiography confirmed patent foramen ovale with an atrial septal aneurysm and a right-to-left intracardiac shunt within 3-6 cardiac cycles, establishing a diagnosis of platypnea-orthodeoxia syndrome. Percutaneous patent foramen ovale closure was successfully performed. After the procedure, no residual shunting was observed, and platypnea-orthodeoxia syndrome symptoms significantly improved. Currently, the patient is in good general condition, and no breathlessness is observed. A high index of suspicion for platypnea-orthodeoxia syndrome is recommended for elderly patients with unexplained hypoxia and shortness of breath. Identification of the underlying mechanisms of platypnea-orthodeoxia syndrome will help determine future therapeutic options. An enlarged aortic root may be the most likely cause of right-to-left shunting in patients with patent-foramen-ovale-induced platypnea-orthodeoxia syndrome. More attention should be paid to aortic root size.

#5

The Impact of Intravenous Agitated Saline Contrast Echocardiography on Subclinical Neuronal Injury Determined By Neuron-Specific Enolase.

Anatolian journal of cardiology2026 Feb 23

Patent foramen ovale (PFO) is a congenital defect of the interatrial septum with 25%-30% prevalence. Diagnostic echocardiography involves the injection of agitated saline, and microbubble passage from the right to the left atrium is monitored. The reliability of this method has been questioned in case series, with a low incidence (0.062%) of generally transient, mild clinical cerebrovascular events. This study aimed to examine whether transthoracic echocardiography, which was performed on patients with PFO and atrial septal aneurysm (ASA) without neurological history, and healthy controls can cause silent neuronal injury by evaluating neuronspecific enolase (NSE) with saline contrast echocardiography (SCE). Fifty-two patients who underwent SCE for color flow through the interatrial septum or prominent interatrial septal aneurysm and were diagnosed with PFO were included. Fifty-one control patients without PFO or ASA were included. Serum samples were collected from the patients before and 12 hours after the SCE test, and NSE levels were measured by Enzyme Linked Immunosorbent Assay (ELISA). Median baseline NSE levels were 6.4 (2.8-9.6) ng/mL in the PFO/ASA group and 5.3 (3.6-9.1) ng/mL in controls. At 12 hours, median NSE levels remained similar (6.6 (3.8-11.5) vs. 5.8 (4.6-9.6) ng/mL; P = .90). The median change in NSE (ΔNSE) did not differ between groups [1.19 (-1.01 to 2.23) vs. 0.73 (-1.16 to 2.25) ng/mL; P = .58]. There was no relationship between age, presence of interatrial septal aneurysm, mitral annulus calcification, number of bubbles passed in the SCE test, and baseline and 12-h change in NSE levels (P = .926). Neuronspecific enolase level changes were found to be correlated between groups (P < .001). This study is the first to evaluate whether SCE causes silent neuronal injury. It is suggested that when evaluated with NSE, the SCE method is safe and does not cause silent neuronal injury in patients without underlying neuronal susceptibility.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC326 artigos no totalmostrando 198

2026

Percutaneous Patent Foramen Ovale Closure and Aneurysm Elimination by Direct Suture.

JACC. Case reports
2025

Detection of atrial septal aneurysm on ECG based on Deep Learning algorithm (ANN).

La Tunisie medicale
2026

Correlation Between Patent Foramen Ovale Morphological Characteristics and Right-to-Left Shunt Severity in Stroke Patients with High RoPE Scores.

Cerebrovascular diseases (Basel, Switzerland)
2026

Platypnea-orthodeoxia syndrome treated by percutaneous patent foramen ovale closure: a case report and review of the literature.

Journal of medical case reports
2026

The Impact of Intravenous Agitated Saline Contrast Echocardiography on Subclinical Neuronal Injury Determined By Neuron-Specific Enolase.

Anatolian journal of cardiology
2026

Influence of Venous Access Site and Right Atrial Anatomical Variants on the Detection of Patent Foramen Ovale During Agitated Saline Contrast Transesophageal Echocardiography.

Echocardiography (Mount Kisco, N.Y.)
2026

[A case of cryptogenic stroke with platypnea-orthodeoxia syndrome and paroxysmal atrial fibrillation].

Rinsho shinkeigaku = Clinical neurology
2025

Platypnea-Orthodeoxia Syndrome Revealing an Undiagnosed Patent Foramen Ovale: A Case Report.

Cureus
2025

Clinical and echocardiographic characteristics of adults with atrial septal aneurysm.

Archivos peruanos de cardiologia y cirugia cardiovascular
2026

Optimizing patient selection for patent foramen ovale closure after stroke: The CRISP-PFO score.

European journal of internal medicine
2026

Folding atrial septal aneurysm to close multi-fenestrated ASDs and a PFO with a single device.

Cardiovascular intervention and therapeutics
2025

Different faces of atrial septal aneurysm.

Annals of the Academy of Medicine, Singapore
2025

An Updated Meta-Analysis of Patent Foramen Ovale Closure Versus Medical Therapy for Preventing Recurrent Cryptogenic Stroke.

Cureus
2026

Transcatheter Closure for Prevention of Stroke in an Octogenarian Woman With Dual Left Atrial "Appendages".

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography &amp; Interventions
2026

Effectiveness and safety of MemoPart for patent foramen ovale closure in real-world patients.

Minerva medica
2025

Transseptal puncture for PFO with atrial septal aneurysm closure.

Revista espanola de cardiologia (English ed.)
2025

Supracardiac Atherosclerotic Lesions in Embolic Stroke of Undetermined Source: Predicting Stroke Recurrence and Enhancing Secondary Prevention Strategies.

Journal of the American Heart Association
2025

Outcomes Analysis of Transcatheter Closure of Atrial Septal Defects.

Journal of the American Heart Association
2024

GIANT ATRIAL SEPTAL ANEURYSM WITH THROMBI IN A PATIENT WITH ATRIAL SEPTAL DEFECT AND CEREBRAL ISCHEMIC EVENTS: A CASE REPORT.

Acta clinica Croatica
2025

Percutaneous closure of patent foramen ovale with complex anatomy using the Memopart™ occluder device.

American heart journal plus : cardiology research and practice
2025

Platypnoea-orthodeoxia syndrome following transcatheter aortic valve implantation complicated by aortic annular rupture: a case report.

European heart journal. Case reports
2025

Anatomical features of percutaneously closed patent foramen ovale in patients with cryptogenic stroke.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation
2025

Patent Foramen Ovale Closure in Older Patients With Cryptogenic Stroke: Current Evidence and Next Steps.

Structural heart : the journal of the Heart Team
2025

[Patent foramen ovale: is a change in the diagnostic paradigm necessary?].

Medicina
2025

Platypnea-Orthodeoxia Syndrome Post-Pneumonectomy: A Case of Right-To-Left Shunting and Successful PFO Closure.

Clinical case reports
2025

A large atrial septal aneurysm presenting with severe arrhythmias: A case report.

International journal of surgery case reports
2025

Patent Foramen Ovale and Stroke: A Review.

JAMA
2025

Suture-Mediated Patent Fossa Ovalis Closure: Late Clinical Outcomes and Predictors of Technical Success.

JACC. Advances
2025

Right atrial thrombus and paradoxical embolism risk in a trauma patient with patent foramen ovale: case report.

European heart journal. Case reports
2025

Incessant atrial tachycardia associated to atrial septal aneurysm treated by pulsed field ablation.

HeartRhythm case reports
2025

Mitral valve blood cyst with atrial septal aneurysm treated as rheumatic valvular heart disease: a case report and review of literature.

Journal of medical case reports
2025

A High Ratio of D-1 Dimer to Brain Natriuretic Peptide and Large Right-to-Left Shunt by Contrast-Enhanced Transthoracic Echocardiography as Risk Factors for Cryptogenic Stroke in Patent Foramen Ovale.

The Tohoku journal of experimental medicine
2025

Quantitative Volumetric Analysis of the Patent Foramen Ovale Tunnel in Coronary Computed Tomography Angiography: Clinical Implications and Diagnostic Significance.

Journal of computer assisted tomography
2025

Successful Transseptal Puncture of Giant Atrial Septal Aneurysm With a Novel Transseptal Guidewire.

JACC. Case reports
2025

Consistency in Identifying Atrial Septal Aneurysm in PFO-Associated Stroke Patients: A Single-Center Experience.

Journal of the Society for Cardiovascular Angiography &amp; Interventions
2025

Atrial septal aneurysm leading to a cerebrovascular accident in a professional swimmer.

Kardiologia polska
2025

Burden of Modifiable Risk Factors in Young-Onset Cryptogenic Ischemic Stroke by High-Risk Patent Foramen Ovale.

Stroke
2025

Case Image: Secondary Interventional Closure of Dislodged Patent Foramen Ovale Occluder: A Successful Management.

Journal of clinical ultrasound : JCU
2025

Managing anticoagulation and thromboembolic risk in cryptogenic stroke associated with patent foramen ovale.

BMJ case reports
2025

Association of atrial cardiopathy and residual shunt after patent foramen ovale closure in patients experiencing migraine.

European journal of medical research
2025

TOUlouse TAhiTI Stroke Study (TOUTATIS): A comparative analysis of young pacific islanders with ischemic stroke.

Revue neurologique
2025

Long-term cerebrovascular outcomes of patients undergoing percutaneous patent foramen ovale closure in observational studies: a systematic review and meta-analysis.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
2024

Predictors of Residual Right to Left Shunt in Patients Undergoing Percutaneous Transcatheter Patent Foramen Ovale Closure: A New Clue "Inferior Vena Cava-Patent Foramen Ovale Angle".

Journal of clinical medicine
2024

White matter lesions as a prognostic marker of recurrence in cryptogenic stroke with high-risk patent foramen ovale.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
2024

Embolic Ischemic Cortical Stroke in a Young Flight Instructor with a Small Patent Foramen Ovale.

Aerospace medicine and human performance
2024

Registry of Percutaneous Closure of Patent Foramen Ovale in the Secondary Prevention of Stroke.

Arquivos brasileiros de cardiologia
2024

Patent Foramen Ovale and Other Cardiopathies as Causes of Embolic Stroke With Unknown Source.

Journal of stroke
2024

Characteristics of patients diagnosed for cardiac cause of ischemic neurological events and prescreened with a transcranial Doppler examination.

Polish archives of internal medicine
2024

Determinants of adverse outcomes following patent foramen ovale closure in elderly patients.

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
2024

Age-dependent association between aneurysmal and isolated redundant inter-atrial septum with patent foramen ovale.

The international journal of cardiovascular imaging
2025

Pulsed field ablation of atrial tachyarrhythmia originating from atrial septal aneurysm.

Heart rhythm
2024

Morphology and location of thrombus and sludge in patients with non-valvular atrial fibrillation.

BMC cardiovascular disorders
2024

Upsizing of GORE® Cardioform ASD Occluder for Atrial Septal Defect With Atrial Septal Aneurysm.

Cureus
2024

Case Report: Persistent residual shunt after a first percutaneous PFO closure followed by minimally invasive surgical failure: third time is a charm.

Frontiers in cardiovascular medicine
2024

Large atrial septal aneurysm in patient with atrial fibrillation: Just a structural deformation or a clinical problem?

Kardiologia polska
2024

A Rare Case of Platypnea-Orthodeoxia Syndrome in a Patient With Undiagnosed Atrial Septal Defect.

Cureus
2024

Patent Foramen Ovale Occlusion in Elderly Patients: Is It Worth It? A Large, Single-Center Retrospective Analysis.

Journal of clinical medicine
2024

Acute Ischemic Stroke Superimposed on Acute Pulmonary Embolism in the Presence of Patent Foramen Ovale: A Case Report.

Cureus
2024

Atrial Septal Aneurysm Leading to Ischemic Stroke: A Case Report and Literature Review.

Cureus
2024

Morphological Features of Patent Foramen Ovale Compared Between Older and Young Patients With Cryptogenic Ischemic Stroke.

Circulation journal : official journal of the Japanese Circulation Society
2024

Device Closure or Antithrombotic Therapy After Cryptogenic Stroke in Elderly Patients With a High-Risk Patent Foramen Ovale.

Journal of stroke
2024

European Stroke Organisation (ESO) Guidelines on the diagnosis and management of patent foramen ovale (PFO) after stroke.

European stroke journal
2024

Atrial Septal Abnormalities and Cryptogenic Stroke: A Cross-Sectional Study.

Cardiovascular &amp; hematological disorders drug targets
2024

A Patent Foramen Ovale With an Atrial Septal Aneurysm in a Patient Presenting With Deep Vein Thrombosis and Pulmonary Embolism.

Cureus
2024

Assessment of the Characteristics of Patent Foramen Ovale Associated with Cryptogenic Stroke.

Current medical imaging
2024

Giant Aneurysm of the Interatrial Septum: A Multidisciplinary Approach.

JACC. Case reports
2024

Ignored Role of Paroxysmal Atrial Fibrillation in the Pathophysiology of Cryptogenic Stroke in Patients with Patent Foramen Ovale and Atrial Septal Aneurysm.

Current cardiology reviews
2024

Does Atrial Septal Anatomy Still Matter in the Etiological Evaluation of Ischemic Stroke Beyond the Age of 60?

Journal of the American Heart Association
2024

Is Moderate/Large Residual Shunt After PFO Closure Justifiable for a Patient with a Prior History of Cryptogenic Stroke and Transient Ischemic Attack?

International heart journal
2024

Relationship between patent foramen ovale anatomical features and residual shunt after patent foramen ovale closure.

Cardiovascular intervention and therapeutics
2024

In young patients with stroke of undetermined etiology, large vessel occlusions are less frequent in the group with high-risk patent foramen ovale.

Revue neurologique
2024

Retinal arterial occlusion and patent foramen ovale: A case study-based review.

Journal francais d'ophtalmologie
2023

Percutaneous closure of 'complex' multi-fenestrated atrial septal aneurysm in visceral situs inversus using a multi-device approach: a case report.

European heart journal. Case reports
2023

Assessment of Bi-Atrial Mechanical Function in Patients with Isolated Atrial Septal Aneurysm.

Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir
2023

High-risk patent foramen ovale and elderly in cryptogenic stroke.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
2023

Comparative evaluation of intracardiac, transesophageal, and transthoracic echocardiography in the assessment of patent foramen ovale: A retrospective single-center study.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography &amp; Interventions
2023

Three-Dimensional Cardiac Imaging: A Necessity to the Diagnosis and Treatment of Swiss-Cheese Atrial Septal Defect.

Cureus
2023

An Unusual Cause of Acute Right-Sided Heart Failure Presenting With Refractory Hypoxia.

Cureus
2023

Patent foramen ovale closure with the Occlutech Figulla flex II device: A long-term (up to 10-years) follow-up.

International journal of cardiology
2023

Anatomical predictors for suture-based closure of the patent foramen ovale: A multicenter experience.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography &amp; Interventions
2023

Pearls and Pitfalls in the Transesophageal Echocardiographic Diagnosis of Patent Foramen Ovale.

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
2023

Acute hypoxemia due to right-to-left shunt via a patent foramen ovale during left internal thoracic artery to left anterior descending artery anastomosis in off-pump coronary artery bypass grafting: a case report.

JA clinical reports
2022

Effect of atrial septal dilation tumor and patent foramen rotundus on cryptogenic ischemic stroke in young and middle-aged patients.

African health sciences
2023

Successful percutaneous closure of a large complex patent foramen ovale with an atrial septal aneurysm and two small atrial septal defects using a novel biodegradable occluder.

European heart journal. Case reports
2024

The Utility of Echocardiogram in the Workup of Ischemic Stroke Patients.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
2022

Change in patent foramen ovale height is associated with cryptogenic stroke and the construction of a morphology-based scoring system.

Frontiers in cardiovascular medicine
2022

Machine learning in a real-world PFO study: analysis of data from multi-centers in China.

BMC medical informatics and decision making
2022

Atrial Septal Aneurysm: An Incidental Finding or a Clinically Significant Anomaly?

Cureus
2022

Association of Atrial Septal Aneurysm and Shunt Size With Stroke Recurrence and Benefit From Patent Foramen Ovale Closure.

JAMA neurology
2022

Echocardiographic characteristics of transcatheter closure of patent foramen ovale with mallow biodegradable occluder: A single-center, phase III clinical study.

Frontiers in cardiovascular medicine
2022

Effect of ASA on the risk of cerebrovascular ischemic events in patients with PFO.

Annals of clinical and translational neurology
2022

Fetal Atrial Flutter Associated with Atrial Septal Aneurysm.

Diagnostics (Basel, Switzerland)
2022

Study of Transesophageal Echocardiography in Young Patients with Cryptogenic Stroke: Prevalence of Patent Foramen Ovale and Interpretation of the RoPE Score.

Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir
2022

Large Atrial Septal Aneurysm Associated with Secundum Atrial Septal Defect.

CASE (Philadelphia, Pa.)
2022

Fetal Atrial Septal Aneurysm: Follow-Up from Second to Third Trimester.

Diagnostics (Basel, Switzerland)
2022

Transjugular Approach to Closure of Patent Foramen Ovale Under the Guidance of Fluoroscopy and Transthoracic Echocardiography: A Case Report.

Frontiers in cardiovascular medicine
2022

Potential Embolic Sources Differ in Patients With Embolic Stroke of Undetermined Source According to Age: A 15-Year Study.

Frontiers in neurology
2022

[Lung Cancer Associated with Atrial Septal Aneurysm Detected on Preoperative Echocardiogram].

Kyobu geka. The Japanese journal of thoracic surgery
2022

A sudden infant death associated with atrial septal aneurysm and abnormality of the connecting site between the inferior vena cava and right atrium.

Legal medicine (Tokyo, Japan)
2022

Transcatheter closure of fenestrated atrial septal aneurysm in children: Feasibility and long-term results.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography &amp; Interventions
2022

Cryptogenic Ischemic Stroke in Migraine: Role of Patent Foramen Ovale.

Frontiers in pain research (Lausanne, Switzerland)
2022

The Many Faces of the Interatrial Septum: A Diagnostic Dilemma and Considerations for Defect Closure Device Selection.

Journal of cardiothoracic and vascular anesthesia
2022

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure.

Journal of visualized experiments : JoVE
2023

Atrial septal aneurysm contribution to the risk of cryptogenic stroke in patients with patent foramen ovale: A brief updated systematic review and meta-analysis.

Trends in cardiovascular medicine
2022

Percutaneous Patent Foramen Ovale Closure in Patients with Cryptogenic Stroke or Transient Ischemic Attack: A Retrospective Study.

BioMed research international
2022

[Thalamic infarction following paradoxical embolism during total hip replacement : Case report and pathophysiological considerations].

Die Anaesthesiologie
2022

Hypoxemia found after hospitalization with right hemiplegia due to cerebral infarction: platypnea-orthodeoxia syndrome in the older people.

Journal of cardiology cases
2021

Heterogeneity of Treatment Effects in an Analysis of Pooled Individual Patient Data From Randomized Trials of Device Closure of Patent Foramen Ovale After Stroke.

JAMA
2021

Atrial fibrillation screening on systematic ambulatory electrocardiogram monitoring after percutaneous patent foramen ovale closure: A prospective study.

International journal of cardiology. Heart &amp; vasculature
2021

Importance of direct right-to-left shunt as high-risk patent foramen ovale associated with cryptogenic stroke.

Echocardiography (Mount Kisco, N.Y.)
2022

Cost-effectiveness analysis of patent foramen ovale closure with Amplatzer plus medical therapy compared to medical therapy in patients with a history of stroke in France.

Journal of cardiology
2021

A Comparison Between Gore Cardioform and Amplatzer Septal Occluder for Percutaneous Closure of Patent Foramen Ovale Associated With Atrial Septal Aneurysm: Clinical and Echocardiographic Outcomes.

The Journal of invasive cardiology
2021

Prevalence of Patent Foramen Ovale in a Cohort of Children With Cryptogenic Ischemic Stroke.

Neurology
2021

Patent foramen ovale closure in India; Feasibility, challenges and mid-term outcomes.

Indian heart journal
2021

Concomitant pulmonary embolism and upper limb ischaemia as a first presentation of a patent foramen ovale.

BMJ case reports
2022

Atrial Septal Aneurysms - A Clinically Relevant Enigma?

Heart, lung &amp; circulation
2021

Increased Mobility of the Atrial Septum in Aortic Root Dilation: An Observational Study on Transesophageal Echocardiography.

Frontiers in physiology
2022

Prominent prolapsing Chiari network: presentation and prognosis in paediatric patients.

Cardiology in the young
2021

A meta-analysis of the association of atrial septal abnormalities and atrial vulnerability.

Medicine
2021

Acute unilateral vision loss from central retinal artery occlusion associated with an atrial septal aneurysm and a patent foramen ovale: a case report.

Family practice
2021

Patent Foramen Ovale Channel Morphometric Characteristics Associated with Cryptogenic Stroke: The MorPFO Score.

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
2022

Transcatheter closure of fenestrated atrial septal aneurysm: feasibility and long-term results.

Journal of cardiovascular medicine (Hagerstown, Md.)
2021

Atrial Septal Aneurysm and Atrial Septal Defect Association - an Uncommon But Well- Recognized Association.

Brazilian journal of cardiovascular surgery
2021

Multisystem thromboembolism in a COVID-19 patient: a case report.

Journal of community hospital internal medicine perspectives
2021

Platypnea-orthodeoxia syndrome in patent foramen ovale and fenestrated atrial septal aneurysm with normal right atrial pressure: what is the culprit?

BMJ case reports
2021

[Patent foramen ovale and stroke].

La Revue du praticien
2021

Platypnea and orthodeoxia syndrome as an uncommon clinical indication for a challenging percutaneous patent foramen ovale closure: a case report.

European heart journal. Case reports
2021

Cardiac and Echocardiographic Markers in Cryptogenic Stroke with Incidental Patent Foramen Ovale.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
2021

Surgical management of a giant atrial septal aneurysm.

Clinical case reports
2022

Wide-ranging clinical spectrum of paradoxical embolism.

Postgraduate medical journal
2021

Closure or medical therapy of patent foramen ovale in cryptogenic stroke: prospective case series.

Neurological research and practice
2021

Ischemic colitis and atrial septal aneurysm as a potential cause of systemic thromboembolism.

Clinical case reports
2021

Multidisciplinary assessment of patients with ischemic stroke, the structure of a stroke team, and first Egyptian experience in adults undergoing transcatheter PFO closure for PFO-related stroke.

The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology
2020

Device closure for patent foramen ovale in patients with cryptogenic stroke: which patients should get it?

European heart journal supplements : journal of the European Society of Cardiology
2021

Individualized Experience With Percutaneous Transcatheter Closure of Multiple Atrial Septal Defects: A Single-Center Study.

Frontiers in cardiovascular medicine
2021

Patent foramen ovale closure in non-lacunar cryptogenic ischemic stroke: where are we now?

Journal of geriatric cardiology : JGC
2020

Importance of Persistent Right-to-Left Shunt After Patent Foramen Ovale Closure in Cryptogenic Stroke Patients.

Texas Heart Institute journal
2020

Left Atrial Function in Young Patients With Cryptogenic Stroke and Patent Foramen Ovale: A Left Atrial Longitudinal Strain Study.

Frontiers in neurology
2021

Transcatheter closure of patent foramen ovale: Current evidence and future perspectives.

Journal of cardiology
2020

Predictive value of free fatty acid levels in embolic stroke of undetermined source: A retrospective observational study.

Medicine
2020

Predictors of Residual Right-to-Left Shunt After Percutaneous Suture-Mediated Patent Fossa Ovalis Closure.

JACC. Cardiovascular interventions
2021

Transcranial Doppler as a Screening Tool for High-Risk Patent Foramen Ovale in Cryptogenic Stroke.

Journal of neuroimaging : official journal of the American Society of Neuroimaging
2020

Rare Association of Patent Foramen Ovale and Atrial Septal Aneurysm Leading to Branch Retinal Artery Occlusion in a Young Healthy Man.

Cureus
2021

Atrial Septal Aneurysm may Cause In-Hospital Recurrence of Cryptogenic Stroke.

Journal of atherosclerosis and thrombosis
2020

Patent foramen ovale closure in children without cardiopathy: Child-PFO study.

Archives of cardiovascular diseases
2020

Patent Foramen Ovale in Cryptogenic Ischemic Stroke: Direct Cause, Risk Factor, or Incidental Finding?

Frontiers in neurology
2020

A gigantic atrial septal aneurysm.

European heart journal. Case reports
2020

Prior Stroke in PFO Patients Is Associated With Both PFO-Related and -Unrelated Factors.

Frontiers in neurology
2020

Dramatic Aneurysmal Atrial Septum Identified with Intracardiac Echo Complicating Transseptal Puncture.

CASE (Philadelphia, Pa.)
2020

Transseptal occluder migration after transcatheter atrial septal aneurysm and double secondary septal defect correction: A case report.

Radiology case reports
2020

'Windsock' type atrial septal aneurysm in an adult causing paradoxical embolism.

Cardiology journal
2020

Residual Shunt After Patent Foramen Ovale Closure and Long-Term Stroke Recurrence: A Prospective Cohort Study.

Annals of internal medicine
2020

Acute cerebral infarction with acute myocardial infarction due to patent foramen ovale: A case report.

Medicine
2020

Risk Management: "High-Risk" PFOs Come Into Partial Focus.

Journal of the American College of Cardiology
2020

Atrial Septal Aneurysm, Shunt Size, and Recurrent Stroke Risk in Patients With Patent Foramen Ovale.

Journal of the American College of Cardiology
2020

Cardiovascular MRI: A valuable tool to detect cardiac source of emboli in cryptogenic ischemic strokes.

Brain and behavior
2020

[Isolated atrial septal aneurysm: Exceptional cause of digital ischemia - a case report].

Annales de cardiologie et d'angeiologie
2020

Simultaneous Multifocal Paradoxical Embolism in an Elderly Patient with Patent Foramen Ovale: A Case Report.

Cureus
2020

Atrial septal aneurysm in pregnancy: echocardiography and obstetric outcomes.

Journal of perinatal medicine
2020

Morphometric Features of Patent Foramen Ovale as a Risk Factor of Cerebrovascular Accidents: A Systematic Review and Meta-Analysis.

Cerebrovascular diseases (Basel, Switzerland)
2020

Study of transesophageal echocardiography in young patients (<40 years) with acute arterial ischemic stroke: A pilot study.

Medical journal, Armed Forces India
2020

Screening and evaluation of newly diagnosed cardiovascular diseases in first-trimester asymptomatic pregnant women in a tertiary antenatal care center in Turkey.

Anatolian journal of cardiology
2020

Fetal atrial septal aneurysm: a differential diagnosis of aortic arch retrograde flow.

BMJ case reports
2020

A giant atrial septal aneurysm causing tricuspid valvular obstruction.

Journal of clinical ultrasound : JCU
2020

Patent foramen ovale and stroke: current evidence and treatment options.

Current opinion in neurology
2020

Reprint of : Transcatheter closure of patent foramen ovale to prevent stroke recurrence in patients with otherwise unexplained ischaemic stroke: Expert consensus of the French Neurovascular Society and the French Society of Cardiology.

Revue neurologique
2019

An atrial septal aneurysm with an organized thrombus in an asymptomatic patient: A case report.

Medicine
2019

Stroke in the Young: a Global Update.

Current neurology and neuroscience reports
2020

Correlations between serum homocysteine levels and RoPE score in patients with patent foramen ovale.

Heart and vessels
2020

Association between atrial septal aneurysm and arrhythmias.

Scandinavian cardiovascular journal : SCJ
2019

Role of 3D transesophageal echocardiography in transcatheter closure of atrial septal aneurysms.

Echocardiography (Mount Kisco, N.Y.)
2019

Is there any association between rs1303 (Pi*M3) variant of alpha-1 antitrypsin gene and atrial septal aneurysm development?

Journal of cardiac surgery
2019

Frugal innovation in the cardiac catheter laboratory: Retrograde balloon mitral valvuloplasty using extra back-up guide catheter.

Journal of cardiology cases
2019

Transcatheter closure of patent foramen ovale to prevent stroke recurrence in patients with otherwise unexplained ischaemic stroke: Expert consensus of the French Neurovascular Society and the French Society of Cardiology.

Archives of cardiovascular diseases
2019

Long-Term Outcome After Percutaneous Closure of Patent Foramen Ovale for Cryptogenic Ischemic Events.

The Journal of invasive cardiology
2019

Left atrial enlargement as a maker of significant high-risk patent foramen ovale.

The international journal of cardiovascular imaging
2019

Management of Patients with Patent Foramen Ovale and Cryptogenic Stroke: An Update.

Cardiology
2019

Atrial septal aneurysm with rare comorbid pulmonary arteriovenous malformation as aetiology for cryptogenic stroke.

BMJ case reports
2019

Arterial embolism in a patient with pulmonary embolism and patent foramen ovale.

Proceedings (Baylor University. Medical Center)
2019

Identification of High-Risk Patent Foramen Ovale Associated With Cryptogenic Stroke: Development of a Scoring System.

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
2019

Who benefits from percutaneous closure of patent foramen ovale vs medical therapy for stroke prevention? In-depth and updated meta-analysis of randomized trials.

World journal of cardiology
2019

Cutis marmorata in decompression sickness is associated with a patent foramen ovale.

Echocardiography (Mount Kisco, N.Y.)
2019

Echocardiographic Findings in Patients with Atrial Septal Aneurysm: A Prospective Case-Control Study.

Cardiology research and practice
2019

Device Closure of Patent Foramen Ovale for Cryptogenic Stroke: Patient Selection and Outcomes According to New Randomized Trials.

Current cardiology reports
2019

Insertable cardiac monitor detection of silent atrial fibrillation in candidates for percutaneous patent foramen ovale closure.

Journal of cardiovascular medicine (Hagerstown, Md.)
2019

Updated meta-analysis of closure of patent foramen ovale versus medical therapy after cryptogenic stroke.

Cardiovascular revascularization medicine : including molecular interventions
2020

[Patent foramen ovale with a license to kill].

Medizinische Klinik, Intensivmedizin und Notfallmedizin
2019

Cardioembolic Sources in Patients With Small Single Subcortical Infarcts.

The neurologist
2019

Closure of patent foramen ovale and "cryptogenic" stroke: What's new, what's next?

Archives of cardiovascular diseases
2019

Are we there yet with patent foramen ovale closure for secondary prevention in cryptogenic stroke? A systematic review and meta-analysis of randomized trials.

SAGE open medicine
2018

Current management aspects in adult congenital heart disease: non-surgical closure of patent foramen ovale.

Cardiovascular diagnosis and therapy
2019

Patent foramen ovale closure versus medical therapy for cryptogenic stroke: An updated systematic review and meta-analysis.

Indian heart journal
2018

Cryptogenic Stroke: To Close a Patent Foramen Ovale or Not to Close?

Journal of central nervous system disease
2018

Clinical relevance of atrial septal aneurysm and patent foramen ovale with migraine.

World journal of clinical cases
2018

Updated Meta-analysis on the Closure of Patent Foramen Ovale in Reduction of Stroke Rates: the DEFENSE-PFO Trial Does not Change the Scenario.

Brazilian journal of cardiovascular surgery
2019

A Proposed Etiology for Atrial Tachyarrhythmia in Neonates with Atrial Septal Aneurysms.

Pediatric cardiology
2018

Electrocardiography-gated dual-source computed tomography in the detection of atrial septal aneurysm.

Experimental and therapeutic medicine
2018

Giant atrial septal aneurysm prolapsing into the right ventricle in an asymptomatic infant.

Anatolian journal of cardiology
Ver todos os 326 no EuropePMC

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Doenças relacionadas

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. [A case of cryptogenic stroke with platypnea-orthodeoxia syndrome and paroxysmal atrial fibrillation].
    Rinsho shinkeigaku = Clinical neurology· 2026· PMID 41638677mais citado
  2. Percutaneous Patent Foramen Ovale Closure and Aneurysm Elimination by Direct Suture.
    JACC. Case reports· 2026· PMID 41848452mais citado
  3. Correlation Between Patent Foramen Ovale Morphological Characteristics and Right-to-Left Shunt Severity in Stroke Patients with High RoPE Scores.
    Cerebrovascular diseases (Basel, Switzerland)· 2026· PMID 41843718mais citado
  4. Platypnea-orthodeoxia syndrome treated by percutaneous patent foramen ovale closure: a case report and review of the literature.
    Journal of medical case reports· 2026· PMID 41787477mais citado
  5. The Impact of Intravenous Agitated Saline Contrast Echocardiography on Subclinical Neuronal Injury Determined By Neuron-Specific Enolase.
    Anatolian journal of cardiology· 2026· PMID 41725462mais citado
  6. Prenatal Detection of Interatrial Septal Aneurysm With Postnatal Follow-Up: A Rare Pediatric Case of Arrhythmia in a Two-Year-Old Male.
    Cureus· 2026· PMID 41970153recente
  7. Comparison of safety and short-term outcomes of septostomy and direct tunnel passage techniques in percutaneous patent foramen ovale closure: a multicenter experience.
    Front Cardiovasc Med· 2026· PMID 41969671recente
  8. Atrial Septal Aneurysms: The Heart's Hidden Bulge.
    Acta Cardiol Sin· 2026· PMID 41907032recente
  9. Platypnea-Orthodeoxia Syndrome Caused by Patent Foramen Ovale Successfully Treated With Percutaneous Closure.
    JACC Case Rep· 2026· PMID 41885659recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:99107(Orphanet)
  2. MONDO:0020438(MONDO)
  3. GARD:19651(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Q55789372(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Aneurisma do septo auricular
Compêndio · Raras BR

Aneurisma do septo auricular

ORPHA:99107 · MONDO:0020438
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qPCR para deleção de SMN1 em sangue seco
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1:10.000
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C0521533
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