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Degeneração hipertrófica da oliva
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Introdução

O que você precisa saber de cara

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O núcleo olivar inferior (NOI) é uma estrutura encontrada no bulbo, abaixo do núcleo olivar superior. Em vertebrados, sabe-se que o NOI coordena sinais da medula espinhal para o cerebelo, a fim de regular a coordenação motora e o aprendizado. Foi demonstrado que essas conexões são intimamente associadas, pois a degeneração do cerebelo ou do NOI resulta na degeneração do outro.

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1 ensaio
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Publicações científicas
223 artigos
Último publicado: 2026 Feb

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Publicações mais relevantes

Timeline de publicações
151 papers (10 anos)
#1

Post-traumatic Hypertrophic Olivary Degeneration with Palatal Myoclonus-A Case Report.

Journal of child neurology2026 Mar 03

This is a case report of a 7-year-old boy with a medical history of a motor vehicle accident (MVA) 2 years previously. Two years post-MVA, he developed quivering and twitching of the right side of his lip, palate, and neck. Multiple antiseizure medications were attempted with no effect. However, carbamazepine was started with marked improvement. The most recent brain magnetic resonance imaging showed findings suggestive of hypertrophic olivary degeneration (HOD). Electroencephalography captured the abnormal facial twitching with audible palatal clicking, but was not associated with electrographic changes. This case demonstrates the anatomic importance of the Guillain-Mollaret triangle, as traumatic disruption of this pathway resulted in palatal myoclonus. HOD occurring due to trauma is an incredibly rare etiology, with only 1 other case reported in the literature in a 27-year-old man, with no previous reports of posttraumatic HOD occurring in an individual under 18 discovered during our literature review.

#2

Hypertrophic olivary degeneration mimicking tumor recurrence after brainstem radiosurgery: A diagnostic pitfall in neuro-oncology.

Surgical neurology international2026

Hypertrophic olivary degeneration (HOD) is a rare trans-synaptic degeneration of the inferior olivary nucleus resulting from disruption of the dentato-rubro-olivary pathway, also known as the Guillain- Mollaret triangle. Unlike most degenerative processes, it produces olivary hypertrophy rather than atrophy. In oncology patients with prior posterior fossa or brainstem involvement, this condition can simulate tumor recurrence or radiation necrosis, leading to unnecessary interventions if unrecognized. A 38-year-old woman with a history of human epidermal growth factor receptor 2-positive invasive ductal carcinoma of the breast and previously treated brainstem metastasis presented with progressive right facial paresthesias and gait instability. Neurological examination revealed dysmetria, impaired rapid alternating movements, and gait ataxia without motor or sensory deficits. Magnetic resonance imaging (MRI) demonstrated a nodular enhancing pontine lesion due to the treated metastatic lesion and a new enlargement involving the rostral aspect of the left central tegmental tract with associated hypertrophic change of the inferior olivary nucleus, consistent with unilateral HOD. Magnetic resonance spectroscopy and perfusion imaging excluded neoplastic recurrence. A multidisciplinary neuro-oncology board concluded that the findings were secondary to radiation-induced tract injury. The patient continued maintenance chemotherapy and received symptomatic management and rehabilitative therapy, with serial MRI showing stability. HOD should be considered in patients with prior brainstem surgery or radiotherapy who develop delayed cerebellar signs and characteristic MRI findings. Recognizing its benign and self-limited nature is crucial to prevent misdiagnosis as tumor recurrence and avoid unnecessary oncologic or surgical interventions. Integration of advanced MRI techniques and multidisciplinary evaluation allows precise diagnosis and tailored management, ensuring appropriate treatment and long-term follow-up.

#3

Inferior olive lesions in autoimmune glial fibrillary acidic protein astrocytopathy: a report of two cases.

BMC neurology2026 Jan 31

Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is a newly identified inflammatory nervous system disorder characterized by Immunoglobulin G autoantibodies against GFAP. While several MRI features are considered typical for autoimmune GFAP astrocytopathy, reports of lesions affecting the inferior olivary nucleus (ION) are rare. In this context, we present two cases of autoimmune GFAP astrocytopathy with lesions in the ION. Case 1 involved a 64-year-old man with meningoencephalomyelitis, peripheral neuropathy, and autonomic dysfunction. His brain MRI revealed bilateral ION lesions and changes along the dentato–rubro–olivary pathway, likely indicating hypertrophic olivary degeneration (HOD). Spinal cord MRI showed bilateral T2 hyperintensities in the anterior horns and a longitudinally extensive spinal cord lesion. In Case 2, a 60-year-old man presented with meningoradiculitis. Although he lacked encephalitic symptoms, his brain MRI showed a left ION lesion with radial perivascular enhancement in the periventricular white matter. The olivary lesion was not linked to other abnormalities along the dentato–rubro–olivary pathway, and contrast enhancement appeared in the same region before the T2 lesion was visible. These findings imply that the inferior olivary involvement in Case 2 was a primary inflammatory lesion. Palatal tremor was not observed in either case. In autoimmune GFAP astrocytopathy, lesions in the ION can appear either as a primary inflammatory response or as HOD resulting from disruption of the dentato–rubro–olivary pathway. When ION lesions are detected during an acute phase that suggests inflammation, autoimmune GFAP astrocytopathy should be included in the differential diagnosis.

#4

Hypertrophic olivary degeneration in a patient with lung cancer.

Practical neurology2026 Jan 13

A 78-year-old woman developed a coarse tremor in her left hand that had persisted for 2 months. 3 years before, she had undergone surgery for lung adenocarcinoma, followed by chemotherapy. On examination, there was a postural and action tremor (3-4 Hz) in the left upper limb, identified as a Holmes tremor, with oculopalatal myoclonus. MR scan of the brain showed bilateral hypertrophic olivary degeneration with hyperintensity of the middle cerebellar peduncles. CT scan of the head showed a calcified lesion in the pontine tegmentum, suggesting disruption of the Guillain-Mollaret triangle, which comprises the dentatorubral, rubro-olivary and olivocerebellar pathways. The underlying cause was a pontine metastasis, evidenced by calcification on CT brain scan. This case highlights the importance of considering underlying malignancy in people with hypertrophic olivary degeneration or related symptoms and emphasises the role of CT brain scanning in identifying metastatic calcification when MR scan findings are inconclusive.

#5

Bilateral Hypertrophic Olivary Degeneration Following Unilateral Mesencephalic Hemorrhage.

Clinical case reports2026 Feb

After a unilateral midbrain hemorrhage, clinicians should recognize that bilateral hypertrophic olivary degeneration may occur, presenting as palatal myoclonus, dysarthria, or tinnitus. This highlights the necessity for timely diagnosis and effective symptom management.

Publicações recentes

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📚 EuropePMC185 artigos no totalmostrando 149

2026

Bilateral Hypertrophic Olivary Degeneration Following Unilateral Mesencephalic Hemorrhage.

Clinical case reports
2026

Post-traumatic Hypertrophic Olivary Degeneration with Palatal Myoclonus-A Case Report.

Journal of child neurology
2026

Hypertrophic olivary degeneration mimicking tumor recurrence after brainstem radiosurgery: A diagnostic pitfall in neuro-oncology.

Surgical neurology international
2026

Inferior olive lesions in autoimmune glial fibrillary acidic protein astrocytopathy: a report of two cases.

BMC neurology
2025

Hypertrophic olivary degeneration secondary to brain abscess: a case report and literature review.

Frontiers in human neuroscience
2025

Hypertrophic olivary degeneration: a 7 Tesla advanced imaging case report.

Frontiers in neuroscience
2025

Multifaceted Mesodiencephalic Triangles: Insights into Hypertrophic Olivary Degeneration and Oculopalatal Tremor Pathophysiology.

Cerebellum (London, England)
2025

Another Rare Cause of Hypertrophic Olivary Degeneration Following Cavernous Malformation Hemorrhage: A Case Report.

Diagnostics (Basel, Switzerland)
2025

Clinical characteristics of hypertrophic olivary degeneration following brainstem or cerebellar hemorrhage.

Scientific reports
2025

Bilateral Hypertrophic Olivary Degeneration After Hemorrhagic Cavernoma.

Stroke
2025

Hypertrophic olivary degeneration following cerebral infarction: a case report.

BMC neurology
2026

Hypertrophic Olivary Degeneration in Brainstem Cavernous Malformations: An Analysis of Predictors and Clinical Implications.

Neurosurgery
2025

Cerebellum theta-burst stimulation as a supplementary treatment for tremor induced by bilateral hypertrophic olivary degeneration: a case report.

Physiotherapy theory and practice
2025

Expanding the Clinical, Pathological, and Molecular Phenotypes of Tetratricopeptide 19 (TTC19) Gene Mutations: A Case Report from India.

Neurology India
2025

Unilateral Idiopathic Hypertrophic Olivary Degeneration: A Case Report.

Cureus
2025

Association of Cerebellar Peduncle Morphometry with Hypertrophic Olivary Degeneration: A Pilot Case-Control Study.

AJNR. American journal of neuroradiology
2026

Hypertrophic olivary degeneration in a patient with lung cancer.

Practical neurology
2025

Hypertrophic olivary degeneration after posterior cranial fossa tumor resection in adults: illustrative case.

Journal of neurosurgery. Case lessons
2025

Natural history, management, and outcomes of cerebellar cavernous malformations: A retrospective study of 130 patients.

Neurosurgical review
2025

Safe Use of Regional Anesthesia in a Patient With Hypertrophic Olivary Degeneration: A Case Report.

A&amp;A practice
2025

Aggressive giant pontine capillary telangiectasia with hypertrophic olivary degeneration and brainstem atrophy: illustrative case.

Journal of neurosurgery. Case lessons
2025

The clinical and neuroradiological features of hypertrophic olivary degeneration following brainstem stroke.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2025

Longitudinal Dentate Nucleus MRI Changes in Hypertrophic Olivary Degeneration: a Case Report.

Clinical neuroradiology
2025

Visualization of tau deposition in the inferior olivary nucleus of a patient with hypertrophic olivary degeneration using [18F]-PI2620.

European journal of nuclear medicine and molecular imaging
2025

Unusual co-occurrence of hypertrophic inferior olivary degeneration with infratentorial cavernomatosis and orbital cavernous hemangioma.

Radiology case reports
2024

Increased intrinsic membrane excitability is associated with olivary hypertrophy in spinocerebellar ataxia type 1.

Human molecular genetics
2025

Radiological Hypertrophic Olivary Degeneration Following Posterior Fossa Tumor Surgery.

World neurosurgery
2025

Hypertrophic Olivary Degeneration: Deafferentation With a Difference on FDG PET/CT.

Clinical nuclear medicine
2024

Diaphragmatic myoclonus post cerebellar hemorrhage: a case report.

BMC neurology
2024

Postoperative brainstem cavernous malformations complicated with LGI1 encephalitis and hypertrophic olivary degeneration: A case report and literature review.

Clinical neurology and neurosurgery
2024

Hypertrophic olivary degeneration secondary to a Guillain Mollaret triangle cavernoma: Two case report.

Radiology case reports
2025

Vestibular Rehabilitation of Patient with Hypertrophic Olivary Degeneration: A Case Report.

Journal of the American Academy of Audiology
2024

Progressive ataxia and palatal tremor (PAPT) with hypertrophic olivary degeneration (HOD): A case report.

Radiology case reports
2024

Clinical and Imaging Profile of Patients with Cerebrotendinous Xanthomatosis - a Video Case Series from India.

Tremor and other hyperkinetic movements (New York, N.Y.)
2024

Hypertrophic Olivary Degeneration Following Traumatic Lesion of the Superior Cerebellar Peduncle.

Neurology India
2024

A Rare Presentation of Idiopathic Unilateral Hypertrophic Olivary Degeneration.

Cureus
2024

Hypertrophic Olivary Degeneration Following Clivus Meningioma Surgery.

Rhode Island medical journal (2013)
2024

Short-Term Efficacy of Cerebello-spinal tDCS and Body Weight-Supported Treadmill Training in the Hypertrophic Olivary Degeneration: a Rare Case Report.

Cerebellum (London, England)
2023

Increased intrinsic membrane excitability is associated with hypertrophic olivary degeneration in spinocerebellar ataxia type 1.

bioRxiv : the preprint server for biology
2023

The Guillain-Mollaret triangle: a key player in motor coordination and control with implications for neurological disorders.

Neurosurgical review
2023

Long-standing myoclonic hand tremor as an isolated symptom of hypertrophic olivary degeneration.

Clinical neurology and neurosurgery
2024

Pac-Man Ghost Sign In Bilateral Hypertrophic Olivary Degeneration.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
2024

Cerebellar cognitive affective syndrome with psychotic features in a patient with hypertrophic olivary degeneration.

The Clinical neuropsychologist
2023

Palatal myoclonus and hypertrophic olivary degeneration following wernekinck commissure syndrome: a case report.

BMC neurology
2023

Hypertrophic olivary degeneration associated with bilateral vocal cord adductor dystonia.

BMC neurology
2023

Bilateral hypertrophic olivary degeneration in symptomatic palatal tremor.

Practical neurology
2022

Peduncular Hallucinosis 7 Months After Pontine Hemorrhage With Hypertrophic Olivary Degeneration: A Case Report.

Brain &amp; NeuroRehabilitation
2023

Successful treatment of paroxysmal painful tonic spasms with carbamazepine in a patient with hypertrophic olivary degeneration.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2022

Holmes tremor: an updated review.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2023

Palato-Pharyngo-Laryngeal Rhythmic Myoclonus in Neuro-Behcet Syndrome: A Case Report.

The Annals of otology, rhinology, and laryngology
2022

Qualitative and quantitative detectability of hypertrophic olivary degeneration in T2, FLAIR, PD, and DTI: A prospective MRI study.

Frontiers in neurology
2022

Bilateral hypertrophic olivary degeneration in a syndrome of sensory ataxic neuropathy with dysarthria and ophthalmoplegia.

Muscle &amp; nerve
2022

Hypertrophic olivary degeneration and palatal myoclonus from a Streptococcus intermedius infection of the brain: illustrative case.

Journal of neurosurgery. Case lessons
2022

Hypertrophic Olivary Degeneration Postoperatively Following Pilocytic Astrocytoma Resection.

World neurosurgery
2022

Hypertrophic olivary degeneration: a description of four cases of and a literature analysis.

Quantitative imaging in medicine and surgery
2022

Structural damage burden and hypertrophic olivary degeneration in pediatric postoperative cerebellar mutism syndrome.

Neurosurgical review
2022

Bilateral Hypertrophic Olivary Degeneration after Pontine Hemorrhage: A Case Report.

World journal of clinical cases
2022

Bilateral Hypertrophic Olivary Degeneration as a Paraneoplastic Syndrome of a Poorly Differentiated Carcinoma of the Upper Gastrointestinal Tract: A Case Report and Literature Review.

The neurologist
2022

Palato-Pharyngo-Laryngeal Myoclonus with Facial Involvement After an Ischemic Stroke.

Movement disorders clinical practice
2021

Bilateral Hypertrophic Olivary Degeneration Following Brainstem Insult: A Retrospective Review and Examination of Causative Pathology.

Neuroscience insights
2021

Multicenter Prospective Analysis of Hypertrophic Olivary Degeneration Following Infratentorial Stroke (HOD-IS): Evaluation of Disease Epidemiology, Clinical Presentation, and MR-Imaging Aspects.

Frontiers in neurology
2021

Iron deposits in the red nucleus at long-term follow-up after hypertrophic olivary degeneration.

Quantitative imaging in medicine and surgery
2021

Hypertrophic olivary degeneration following cerebral trauma managed with rehabilitation - A case report.

JPMA. The Journal of the Pakistan Medical Association
2021

Primary intracranial germ cell tumour originating from right brachium Pontis with hypertrophic Olivary degeneration: a case report.

BMC neurology
2021

Haploinsufficiency of POU4F1 causes an ataxia syndrome with hypotonia and intention tremor.

Human mutation
2021

Peribuccal and pharyngeal myorhythmia as a presenting symptom of hypertrophic olivary degeneration: Expert commentary.

Parkinsonism &amp; related disorders
2021

Mollaret's triangle: An important neuroanatomical territory for all clinicians.

Surgical neurology international
2021

Peribuccal and pharyngeal myorhythmia as a presenting symptom of hypertrophic olivary degeneration.

Parkinsonism &amp; related disorders
2021

Association between paraneoplastic rhombencephalitis and hypertrophic olivary degeneration.

Journal of neurology, neurosurgery, and psychiatry
2021

A Paravermal Trans-Cerebellar Approach to the Posterior Fossa Tumor Causes Hypertrophic Olivary Degeneration by Dentate Nucleus Injury.

Cancers
2020

Temporal Evolution of Hypertrophic Olivary Degeneration in a Pediatric Patient: A Case Report and Review of Literature.

Cureus
2020

Hypertrophic Olivary Degeneration and Movement Disorder in a Patient with Familial Creutzfeldt-Jakob Disease.

Cureus
2020

Hypertrophic olivary degeneration concomitant with bilateral middle cerebellar peduncles Wallerian degeneration following unilateral pontine infarction.

BMC neurology
2020

A meta-analysis of case studies and clinical characteristics of hypertrophic olivary degeneration secondary to brainstem infarction.

Journal of integrative neuroscience
2021

Bilateral hypertrophıc olivary degeneration: case report.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2020

Segmental Myorhythmia with Palatal Tremor Due to Bilateral Hypertrophic Olivary Degeneration in Wilson Disease.

Movement disorders clinical practice
2020

Transient Palatal Tremor and Action Induced Foot and Leg Dystonia due to Hypertrophic Olivary Degeneration: a Case Report.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
2021

Holmes tremor and palatal tremor in hypertrophic olivary degeneration: involvement of brainstem.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2020

A Syndrome of Progressive Ataxia and Palatal Tremor (PAPT) in a Patient with Hypertrophic Olivary Degeneration.

Annals of Indian Academy of Neurology
2020

Palato-pharyngo-laryngeal myoclonus with recurrent retrograde feeding tube migration after cerebellar hemorrhagic stroke: a case report and review of hypertrophic olivary degeneration.

BMC neurology
2020

Transaxonal degenerations of cerebellar connections: the value of anatomical knowledge.

Arquivos de neuro-psiquiatria
2020

Pediatric case of persistent hiccups associated with hypertrophic olivary degeneration.

The Turkish journal of pediatrics
2020

Development of Hypertrophic Olivary Degeneration following Pontine Hemorrhage.

Annals of neurology
2020

Hypertrophic Olivary Degeneration and Holmes Tremor: Case Report and Review of the Literature.

World neurosurgery
2020

Oculopalatal tremor following sequential medullary infarcts that did not cause hypertrophic olivary degeneration.

Cerebellum &amp; ataxias
2019

Hypertrophic olivary degeneration: A case report.

The Indian journal of radiology &amp; imaging
2019

Delayed Occurrence of Hypertrophic Olivary Degeneration after Therapy of Posterior Fossa Tumors: A Single Institution Retrospective Analysis.

Journal of clinical medicine
2019

Ocular Motor and Vestibular Disorders in Brainstem Disease.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society
2019

Palatal tremor and hypertrophic olivary degeneration as sequelae of basilar artery occlusion.

Neurology. Clinical practice
2019

Oculopalatal Tremor Following Pontine Hemorrhage.

The Neurohospitalist
2019

Cerebellar atrophy with Chiari malformation: An example of trans-synaptic degeneration?

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
2019

Posterior fossa syndrome and increased mean diffusivity in the olivary bodies.

Journal of neurosurgery. Pediatrics
2019

Olivary hypertrophy improved by steroid treatment: Two case reports with unique presentations.

Journal of neuroimmunology
2020

Hypertrophic olivary degeneration: a single case report.

Acta neurologica Belgica
2019

Hypertrophic olivary degeneration: A comprehensive review focusing on etiology.

Brain research
2019

Hypertrophic olivary degeneration in a 16-year-old girl after subtotal surgery of a brainstem pilocytic astrocytoma - a case report.

Polish journal of radiology
2019

Combined hypertrophic olivary degeneration and Wallerian degeneration of the bilateral middle cerebellar peduncles: a case report.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2019

Microsurgical Management of Midbrain Cavernous Malformations: Predictors of Outcome and Lesion Classification in 72 Patients.

Operative neurosurgery (Hagerstown, Md.)
2019

Hypertrophic olivary degeneration mimics relapse in neuromyelitis optica spectrum disorder.

Neurology
2019

An Acute Clinical Presentation Associated with Hypertrophic Olivary Degeneration.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
2019

New Radiologic Findings of Hypertrophic Olivary Degeneration in 2 Patients with Brainstem Lymphoma.

World neurosurgery
2019

[Hypertrophic olivary degeneration : Cause of new neurological symptoms after stroke].

Der Nervenarzt
2018

Diffusion Tensor Imaging in a Case of Pontine Bleeding Showing Hypertrophic Olivary Degeneration and Cerebellar Ataxia.

Case reports in neurology
2018

Hypertrophic Olivary Degeneration Following Listerial Rhombencephalitis.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
2018

MRI and Tractography in Hypertrophic Olivary Degeneration.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
2018

Hypertrophic Olivary Degeneration: Neurosurgical Perspective and Literature Review.

World neurosurgery
2018

Hypertrophic olivary degeneration in children after posterior fossa surgery. An underdiagnosed condition.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
2017

Idiopathic bilateral hypertrophic olivary degeneration.

BMJ case reports
2018

Eight-and-a-half syndrome caused by a pontine haemorrhage: a case report and review of the literature.

The International journal of neuroscience
2017

Teaching NeuroImages: Bilateral hypertrophic olivary degeneration following posterior circulation stroke.

Neurology
2018

Unilateral Symptomatic Hypertrophic Olivary Degeneration Secondary to Midline Brainstem Cavernous Angioma: A Case Report and Review of the Literature.

World neurosurgery
2017

Wernekink Commissure Syndrome Secondary to Bilateral Caudal Paramedian Midbrain Infarction Presenting with a Unique "Heart or V" Appearance Sign: Case Report and Review of the Literature.

Frontiers in neurology
2017

Hypertrophic olivary degeneration.

BMJ case reports
2017

Progressive ataxia and palatal tremor: Two autopsy cases of a novel tauopathy.

Movement disorders : official journal of the Movement Disorder Society
2017

Hypertrophic Olivary Degeneration and Palatal or Oculopalatal Tremor.

Frontiers in neurology
2017

Pontine Hemorrhage Causing Bilateral Hypertrophic Olivary Degeneration.

Journal of neurosciences in rural practice
2018

Bilateral surgical damage of the central tegmental tract resulting in bilateral hypertrophic olivary degeneration: An MRI case report.

The neuroradiology journal
2017

Hypertrophic olivary degeneration after cerebellar hemorrhage.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
2017

Longitudinal Quantification of Eye-Movement Impairments after Pontine Hemorrhage.

Frontiers in neurology
2017

Respiratory difficulty with palatal, laryngeal and respiratory muscle tremor in adult-onset Alexander's disease.

BMJ case reports
2017

The dentato-rubro-olivary pathway revisited: New MR imaging observations regarding hypertrophic olivary degeneration.

Clinical anatomy (New York, N.Y.)
2015

Deterioration of palatal myoclonus after acute thalamic hemorrhage.

Translational neuroscience
2016

Post-operative pediatric cerebellar mutism syndrome and its association with hypertrophic olivary degeneration.

Quantitative imaging in medicine and surgery
2016

Track density imaging of hypertrophic olivary degeneration from multiple sclerosis plaque.

BJR case reports
2016

Hypertrophic olivary degeneration: Case series and review of literature.

Journal of the neurological sciences
2016

Bilateral Hypertrophic Olivary Degeneration and Holmes Tremor without Palatal Tremor: An Unusual Association.

Tremor and other hyperkinetic movements (New York, N.Y.)
2016

Imaging Features of Hypertrophic Olivary Degeneration.

Journal of the Belgian Society of Radiology
2016

Hypertrophic olivary degeneration: unveiling the triangle of Guillain-Mollaret.

Arquivos de neuro-psiquiatria
2017

Oculomandibular Tremor and Bilateral Hypertrophic Olivary Degeneration.

Movement disorders clinical practice
2016

Hypertrophic olivary degeneration: A clinico-radiologic study.

Parkinsonism &amp; related disorders
2015

Identifying quantitative imaging features of posterior fossa syndrome in longitudinal MRI.

Journal of medical imaging (Bellingham, Wash.)
2016

Hypertrophic Olivary Degeneration Does Not Reduce Essential Tremor.

Movement disorders clinical practice
2016

Pure Progressive Ataxia and Palatal Tremor (PAPT) Associated with a New Polymerase Gamma (POLG) Mutation.

Cerebellum (London, England)
2015

Hypertrophic olivary degeneration due to the presence of pontine cavernomas.

Neurology India
2016

Hypertrophic Olivary Degeneration: A Neurosurgical Point of View.

Journal of neurological surgery. Part A, Central European neurosurgery
2015

A case of hypertrophic olivary degeneration after resection of cavernomas of the brain stem and review of the literature.

Neuropsychiatric disease and treatment
2015

Neuro-Behçet: Pons Involvement with Longitudinal Extension to Midbrain and Hypertrophic Olivary Degeneration.

Case reports in neurology
2015

Hypertrophic olivary degeneration secondary to central tegmental tract injury.

Radiologia brasileira
2015

Postoperative posterior fossa syndrome: unraveling the etiology and underlying pathophysiology by using magnetic resonance imaging.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
2015

Hypertrophic olivary degeneration secondary to traumatic brain injury: a unique form of trans-synaptic degeneration.

BMJ case reports
2015

Hypertrophic olivary degeneration resulting from posterior fossa masses and their treatments.

Clinical imaging
2015

MRI Findings in Nonlesional Hypertrophic Olivary Degeneration.

Journal of neuroimaging : official journal of the American Society of Neuroimaging
2015

Unusual case of posterior fossa syndrome and bilateral hypertrophic olivary degeneration after surgical removal of a large fourth ventricle ependymoma in an adult.

Acta neurochirurgica
2015

Hypertrophic olivary degeneration secondary to pontine haemorrhage.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
2015

Hypertrophic olivary degeneration - a report of two cases.

Journal of clinical imaging science
2016

Hypertrophic Olivary Degeneration Secondary to Neuro-Behçet's Disease.

Clinical neuroradiology
2015

Teaching NeuroImages: hypertrophic olivary degeneration in a young man with POLG gene mutation.

Neurology
2015

Inferior olivary nucleus involvement in pediatric neurodegenerative disorders: does it play a role in neuroimaging pattern-recognition approach?

Neuropediatrics
2015

Magnetic resonance imaging of hypertrophic olivary degeneration.

Radiologia
Ver todos os 185 no EuropePMC

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Ainda não existe comunidade no Raras para Degeneração hipertrófica da oliva

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Doenças relacionadas

Doenças com sintomas parecidos — ajudam quem ainda está buscando diagnóstico

Ainda não achamos doenças com sintomas parecidos o suficiente.

Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Post-traumatic Hypertrophic Olivary Degeneration with Palatal Myoclonus-A Case Report.
    Journal of child neurology· 2026· PMID 41773572mais citado
  2. Hypertrophic olivary degeneration mimicking tumor recurrence after brainstem radiosurgery: A diagnostic pitfall in neuro-oncology.
    Surgical neurology international· 2026· PMID 41660331mais citado
  3. Inferior olive lesions in autoimmune glial fibrillary acidic protein astrocytopathy: a report of two cases.
    BMC neurology· 2026· PMID 41618205mais citado
  4. Hypertrophic olivary degeneration in a patient with lung cancer.
    Practical neurology· 2026· PMID 40506215mais citado
  5. Bilateral Hypertrophic Olivary Degeneration Following Unilateral Mesencephalic Hemorrhage.
    Clinical case reports· 2026· PMID 41859489mais citado
  6. Holmes Tremor Secondary to a Brainstem Haemorrhage With Partial Symptomatic Improvement Following Levetiracetam Use.
    Cureus· 2026· PMID 41909308recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:684290(Orphanet)
  2. MONDO:0975885(MONDO)
  3. Busca completa no PubMed(PubMed)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Degeneração hipertrófica da oliva
Compêndio · Raras BR

Degeneração hipertrófica da oliva

ORPHA:684290 · MONDO:0975885
Prevalência
<1 / 1 000 000
Casos
158 casos conhecidos
Ensaios
1 ativos
Prevalência
0.0 (Worldwide)
MedGen
EuropePMC
Papers 10a
DiscussaoAtiva

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