Anaphylaxis events in the PIONEER study of avapritinib in indolent systemic mastocytosis.

Management Strategy for Anaphylaxis in a Patient With Suspected or Confirmed Mastocytosis: A Case Report.

Characterization of CD123 expression by mast cells in systemic mastocytosis with multicolor flow cytometry.

Regional disparities in access to epinephrine auto-injectors for children and adults in Italy.

Molecular characterization of pediatric mastocytosis revealed different somatic mutations with uncertain prognostic value.

Mast Cell Mediators and Their Diagnostic Utility in Clonal and Nonclonal Mast Cell Activation Disorders.

Role of KIT signaling in ovarian development and function: Insights from multisystem biology.

Presumed tumor-infiltrating clonal hematopoiesis unmasking a concomitant systemic mastocytosis with associated myeloid neoplasm in a patient with metastatic melanoma.

Aggressive Systemic Mastocytosis Presenting as Diffuse Osteoblastic Bone Disease: A Diagnostic Pitfall Mimicking Metastatic Cancer.

Unexplained Syncope in Mastocytosis: The Role of Early Dermatological Recognition.

Hereditary Alpha-Tryptasemia and Mastocytosis: What We Know and What We Need To Learn.

Investigational Approaches in Treatment of Nonadvanced Mastocytosis.

Multiphasic anaphylaxis in the emergency and intensive care setting.

CD25+ mast cell hyperplasia in myeloid/lymphoid neoplasm with PDGFRA rearrangement mimicking systemic mastocytosis.

A Continuous Oral Regimen of High-Dose Cromolyn Sodium Is Effective for Some Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Patients With Mast Cell Activation Syndrome.

Soluble FcεRI is increased in advanced mastocytosis and acts as a negative regulator of mast cell expansion and activation.

Cytoreduction is a Valid Option for Treatment and Prevention of Anaphylaxis in Systemic Mastocytosis: Case Report and Literature Review.

Prognostic Value of Combining Serum Tryptase and Bone Mineral Density in Predicting Fractures in Systemic Mastocytosis.

Systemic Mastocytosis, KIT and the Effects of KIT Tyrosine Kinase Inhibitors on Mast Cell and Basophil Activation.

Avapritinib improves cutaneous involvement in patients with indolent systemic mastocytosis: Results from the randomized, phase 2, interventional PIONEER study.

Skeletal Involvement in Systemic Mastocytosis: Pathophysiology, Clinical Management, Standards of Care, and Novel Therapeutic Strategies.

Case report: A case of mast cell leukemia treated with avapritinib: from diagnostic challenge to transplantation.

[Aggressive systemic mastocytosis complicated with acute myeloid leukemia harboring the RUNX1::RUNX1T1 fusion gene: a case report].

Nemolizumab as an Alternative Therapeutic Option for Indolent Systemic Mastocytosis.

Enhanced PIEZO1 expression in mast cells of mastocytosis skin lesions: Relevance to Darier's sign.

ISM-1 expression in cutaneous mastocytosis: Diagnostic potential and comparison with CD117.

Relapse of Acute Myeloid Leukemia With Concomitant Systemic Mastocytosis Five Years Post Allogenic Hematopoietic Stem Cell Transplantation.

Journal Club: Mastocytosis: across the spectrum: pathobiology, clinical evaluation, and evolving therapies.

Efficacy and safety of avapritinib in advanced systemic mastocytosis: 4-year follow-up of the PATHFINDER study.

Comparative Analysis of Pediatric and Adult Mastocytosis: Clinical Presentation, Triggers, and Treatment Patterns from a Tertiary Care Registry.

Evidence for dysbiosis in the gut microbiome of patients with systemic mastocytosis.

Adult-onset cutaneous mastocytosis presenting as vulvar papules.

Case Report: A rare case of synchronous ovarian mixed germ cell tumor and mast cell leukemia in a pediatric patient.

KIT Mutant/Core binding factor-negative acute myeloid leukemia might be a complex subgroup with dismal prognosis: a single-center retrospective analysis.

Association between Ehlers-Danlos syndrome and mast cell activation syndrome: Is there scientific evidence?

[Orthostatic macules on the legs].

Refractory cutaneous symptoms in systemic mastocytosis.

Estimation of serum tryptase reference intervals via an indirect method reveal age- and sex-dependent upper limits.

Systemic mastocytosis for the practicing clinician: overview, diagnostic features, prognostication and antiproliferative treatment in the era of targeted therapy.

Scroll, like, diagnose? Evaluating mast cell activation syndrome information on TikTok.

Diagnosis, Prognostication, and Management of Patients With Mastocytosis: Status 2026.

Serum Mas-related G protein-coupled receptor X2 concentration in drug-induced immediate hypersensitivity reactions.

Off-label applications of omalizumab: Current insights and perspectives.

Evaluation and differential diagnosis of eosinophilia: A tertiary allergy center experience.

Key Pediatric Dermatologic Conditions: A Clinical Review: Part I.

Spontaneous and experimentally induced lesions in NOD-scid gamma and other NOD-derived mouse strains.

Evaluating the Clinical Relevance of Elevated Mucosal Mast Cells in the Gastrointestinal Tract.

Avapritinib in the treatment of systemic mastocytosis with associated acute myeloid leukemia after poor graft function following allogeneic hematopoietic stem cell transplantation: a case study and review of the literature.

Avapritinib and corticosteroids in advanced systemic mastocytosis with tumoral CMML and associated thrombocytopenia.

Diagnostic Challenges in a Young Man with a Suspected Mast Cell Disorder, Dysplastic Bone Marrow Morphology, and a ZRSR2 Mutation.

Mastocytosis: Imaging Spectrum and Diagnostic Insights.

Alpha-Tryptase Overexpression as a Modifier of Mast Cell-Mediated Reactions.

Correlates of organ damage in patients with advanced systemic mastocytosis enrolled in clinical trials of avapritinib.

Investigating instruments for evaluation of gastrointestinal burdens in patients with systemic mastocytosis: an exploratory multimethod study.

New insight into role of mast cells in erythrocyte homeostasis and clearance under oxidative stress conditions in vivo.

Prevalence of KIT D816V in anaphylaxis or systemic mast cell activation.

Critical role of the mast cell/tryptase/PAR2 axis in anastrozole-induced pain.

Near-Fatal Mastocytosis Mimicking as Malignant Vasovagal Syncope.

Is Bruton tyrosine kinase a potential target to treat mast cell neoplasms? Systemic mastocytosis associated with chronic lymphoid leukemia successfully treated with acalabrutinib monotherapy: a case report and review of the literature.

A Case of Mastocytosis Relapsed in Adulthood After Long-Term Remission in Childhood.

A Treatment Approach for Severe Pain in Mast Cell Activation Syndrome: A Case Report.

Biconcave vertebral fractures as a possible distinctive feature of indolent systemic mastocytosis compared with primary osteoporosis.

Denosumab as a Potential Disease-Modifying Treatment in Indolent Systemic Mastocytosis-Related Osteoporosis.

Darier's Sign in Mastocytosis.

From mechanism to management: CEREMAST perspectives on the intersection of HαT and clonal mast cell disorders.

Inflammatory disorders in IDH-mutated myeloid neoplasms: Characteristics and response to IDH inhibitors.

Distinct clinical, laboratory, molecular, and pathologic features of systemic mastocytosis involving the gastrointestinal tract.

Cardiovascular manifestations in mast cell activation disease: key insights for cardiologists and angiologists.

Updates on Kinase Inhibitors in Allergy.

Management of Mastocytosis and Mast Cell Activation in Children.

Diagnosis and Management of Patients With Mast Cell Activation Syndromes: Status 2026.

Utility of quantifying mast cells in gastrointestinal biopsies in patients with suspected mast cell activation disorder.

Diagnosis and management of mast cell activation syndrome (MCAS) in Canada: a practical approach.

Autonomic function testing and symptom severity in patients with suspected mast cell activation disorders.

Management of skeletal-related events and fracture prevention in systemic mastocytosis.

Diffuse Cutaneous Mastocytosis with Bullous Presentation: A Rare Case Report.

Distinct Tryptase Gene Copy Number Variations Correlate With Tryptase Levels in a Population-Based Cohort.

Chronic Anaphylaxis With Indolent Systemic Mastocytosis: A Case Report.

Langerhans Cell Histiocytosis and Mastocytosis: A Rare Association.

Using natural language processing to identify symptoms in systemic mastocytosis.

Lampson B, Zakharyan A, Shimony SO, Shi H, Deangelo D. Analysis of avapritinib clinical trial data generates a highly accurate predictive model for advanced systemic mastocytosis versus indolent systemic mastocytosis based on peripheral blood testing. Blood. 2024;144(suppl 1):107.

Telomere occupancy by TRF2 is altered by KIT mutations and correlates with mastocytosis regression.

KIT-Targeting Drugs in the Management of Nonadvanced and Advanced Systemic Mastocytosis.

Unmasking mast cell infiltrates: augmented reality and AI in GI endoscopy for systemic mastocytosis.

Pre-diagnostic and non-advanced systemic mastocytosis without cutaneous involvement have an increased risk of anaphylaxis.

Access to a protected setting vaccination for allergic patients: Evaluation of appropriateness. The experience of Bari Policlinico University Hospital.

Final safety and efficacy results from a phase 1/2 study of tagraxofusp, a CD123-targeted therapy, for myelofibrosis.

Case Report: Refractory systemic nmastocytosis with AML1::ETO+ acute myeloid leukemia driven by rare KIT mutation: remarkable therapeutic efficacy of avapritinib.

Challenges in Cutaneous Mastocytosis.

Burden of childhood cutaneous mastocytosis: Severity and caregivers' quality of life.

PSMA-positive bone lesions unmasked: systemic mastocytosis mimicking metastatic prostate cancer.

Anesthetic Considerations for Cesarean Section in a Woman With Systemic Mastocytosis.

Aggressive Systemic Mastocytosis Related to Germline p.D816V KIT Mutation.

Safety of Drug Provocation Tests in Adults With and Without Clonal Mast Cell Disorders.

Practical diagnostic approach to assess myeloid and precursor cell neoplasms on trephine bone marrow biopsies: reflection of middle European reality.

Gender and Allergy: Mechanisms, Clinical Phenotypes, and Therapeutic Response-A Position Paper from the Società Italiana di Allergologia, Asma ed Immunologia Clinica (SIAAIC).

Myeloid Neoplasms with Evidence of the Additive/Cumulative Effect of Molecular Genetic Alterations That "Pave the Way" to a Specific Disease Category or Entity: Lessons Learned from Cases Submitted to the 22nd Meeting of the European Association for Haematopathology/Society of Hematopathology Bone Marrow Workshop Organized by the European Bone Marrow Working Group, Dubrovnik 2024.

Cendakimab (anti-IL-13) administration improves esophageal gene expression in eosinophilic esophagitis.

Omalizumab for Pediatric Cutaneous Mastocytosis: Case Report and Review.

Artificial intelligence predicts c-KIT exon 11 genotype by phenotype in canine cutaneous mast cell tumors: Can human observers learn it?

Diagnosing Systemic Mastocytosis: State of the Art.

c-KIT Small Molecule Inhibitors as a Therapeutic Strategy for Melanoma: Clinical Insights, SAR, and Future Directions.

French guidelines for the management of nonadvanced mastocytosis in adults.

Next Generation Sequencing of Genes With Epigenetic Alterations in Mastocytosis.

Role of Mast Cells in Human Health and Disease: Controversies and Novel Therapies.

Leukocytosis, Monocytosis, and Eosinophilia in Systemic Mastocytosis: Analysis of Phenotype, Genetics and Prognosis in 596 Patients From the GREM Registry.

Incidental detection of systemic mastocytosis in appendectomy.

Allogeneic haematopoietic cell transplantation in advanced systemic mastocytosis in the new era: A CIBMTR study.

Uncommon Presentation of Mastocytosis: Focus on the Xanthelasmoid Variant.

Avapritinib reduces symptoms and mast cell burden in systemic mastocytosis.

Update in stinging insect hypersensitivity.

Understanding Cutaneous Mastocytosis: A Case Report on the Symptoms and Diagnosis of a Rare Disease.

KIT-Negative Systemic Mastocytosis Associated With Acute Myeloid Leukemia.

Aggressive Systemic Mastocytosis Presenting as Pyrexia of Unknown Origin and Sclerotic Bone Lesions: An Uncommon Presentation of a Rare Haematological Disorder.

Crystal-Storing Histiocytosis of Gastrointestinal Tract: Report of 2 Patients and Literature Review.

Tissue-Resident Myeloid and Histiocytic Cells in Health and Disease: Novel Emerging Concepts.

Diffuse Gastric Uptake on 18 F-FDG PET/CT Caused by Involvement of Mastocytosis in a Patient With Systemic Mastocytosis.

Diagnosis, management and the burden of symptoms of mastocytosis from the physician's perspective: A nationwide study.

Assessment of the metabolic stability of avapritinib in human liver microsomes using a fast and green UPLC-MS/MS method: screening for structural alarms associated with metabolic lability and in silico toxicity.

Bone marrow mastocytosis associated with primary cutaneous follicle center lymphoma: an unusual case report.

Preclinical Antitumor Efficacy of a Novel Anti-c-Kit Antibody-Drug Conjugate, NN3201, in c-Kit-Positive Tumors.

Re: "Increased risk of skin cancer in mastocytosis: A large-scale retrospective cohort study of over 20,000 patients".

Mast Cell Leukemia: Comprehensive Review of Literature With Current Insights and Updates on Management.

Gastric biopsies with prominent eosinophils: Clinicopathologic features and response to therapy.

Successful venom immunotherapy with avapritinib in a patient with systemic mastocytosis.

Real-world characteristics of systemic mastocytosis in Romania: insights from a reference-center-based descriptive study.

Novel KIT mutation, D816_N819delinsll, in a patient with systemic mastocytosis: a case report.

Gallbladder Involvement in Aggressive Systemic Mastocytosis.

Innovative Therapeutic Approaches in Systemic Mastocytosis: an Updated Review.

Systemic mastocytosis in paediatric acute myeloid leukaemia with RUNX1::RUNX1T1 fusion.

Impact of Molecular Evaluations in the Biology, Diagnosis, and Prognostication of Patients With Mastocytosis.

Hypermobile Ehlers-Danlos Syndrome: Cerebrovascular, Autonomic and Neuropathic Features.

Mastocytic enterocolitis in a patient with chronic diarrhoea.

Evaluating Melanoma Risk in Adult Mastocytosis: Potential Impact of Detection Bias - A Registry-based Study (Sweden).

Neonatal Aggressive Systemic Mastocytosis Treated With Midostaurin and Systematic Review of the Literature.

Improved diagnostic screening and classification of clonal mast cell diseases by ultrasensitive KIT p.D816V detection.

The Pulmonary Manifestation of Mastocytosis: Experiences of the National Reference Centre of Excellence.

Unmasking systemic mastocytosis: a case of gastrointestinal involvement misdiagnosed as achalasia.

Systemic mastocytosis with an associated myeloid neoplasm: Report from the XVI European Bone Marrow Working Group Course and Workshop, Barcelona 2023.

Well-differentiated systemic mastocytosis: Genetics, mast cell immunophenotypes, and KIT autophosphorylation.

Mast cell conditions and drug allergy.

Midostaurin in daily clinical practice of patients with advanced systemic mastocytosis.

Is blood vitamin B6 a marker of interest for individualized psoriasis disease care management in cardiovascular disease prevention?

When relief is out of reach: living with chronic itch.

The evaluation, management, and future of indolent systemic mastocytosis.

Digital polymerase chain reaction enhances analysis of the cKIT D816V mutation in systemic mastocytosis patients: Clinical insights.

Tyrosine Kinase Inhibitors for the Treatment of Mast Cell Diseases: Review and Update.

Clinical and Biological Characteristics of Four Patients with Aggressive Systemic Mastocytosis Treated with Midostaurin.

Schnitzler syndrome - a rare cause of chronic urticaria. Case report.

Avapritinib versus midostaurin or cladribine in advanced systemic mastocytosis: A retrospective real-world external control study.

The Sting Challenge Test Shows High Negative Predictive Value in Patients Receiving Venom Immunotherapy.

Gastroprotective effect of polysaccharides from Agaricus blazei Murill against ethanol-induced gastric ulcer in mice.

Utility of glucagon-like-peptide-1-receptor agonists in mast cell activation syndrome.

Case report: Experience of a rare case of primary acute mast cell leukemia.

Hereditary α-Tryptasemia and Peripheral Blood KIT D816V Mutation in Patients with Pediatric Mastocytosis.

Hymenoptera anaphylaxis and mast cell activation disorders.

Critical Pitfalls in the Flow Cytometric Analysis of Mast Cells in Patients With Systemic Mastocytosis.

Evolution of mast cell research associated with the Laboratory of Allergic Diseases, 1985-2022: Summary of the 2023 NIAID Symposium.

The number of vertebral fractures in indolent systemic mastocytosis is influenced by presence of the KIT-mutation.

The Use of Biologic Therapeutic Regimens in Cutaneous and Systemic Mastocytosis: A Scoping Review.

Idiopathic mast cell activation syndrome in real-life practice: clinical features and management.

[Avapritinib for systemic mastocytosis with an associated myelodysplastic/myeloproliferative neoplasm: a case report and literature review].

Hereditary alpha-tryptasemia and monoclonal mast cell disorders.

Systemic Mastocytosis in 910 Patients: Prognostic Contribution of the International Consensus Classification in the Context of the Mayo Alliance Prognostic System.

Patient and Advanced Practitioner Perspectives on Symptom Burden and Symptom Management in Indolent Systemic Mastocytosis.

Integrating a Rare Disease into Practice: Development of a Toolkit for Systemic Mastocytosis.

Management of indolent mastocytosis and mast cell activation syndrome: A clinical yardstick.

Pathogenic Mechanisms of Systemic Mastocytosis: Unraveling the Genetic Complexity, Bone Marrow Microenvironment, and Clinical Challenges.

Idiopathic cutaneous Mastocytosis mimicking infantile psoriasis in a six-month-old male: a rare presentation.

Patient-Reported Outcomes and Provider Perceptions of Systemic Mastocytosis: Results From the PRISM Study.

Avapritinib monotherapy induces rapid and deep remission of heavily treated, KIT D816H-mutated t(8;21) acute myeloid leukemia, a case report and literature review.

Indolent Mastocytosis and Bone Health: Molecular Mechanisms and Emerging Treatment Options.

Severe Anemia With Intraosseous-Intramuscular Hemorrhage in a Patient With Kit-C-Negative Systemic Mastocytosis.

Non allergic gastrointestinal manifestations of hereditary alpha-tryptasemia.

Telangiectasia Macularis Eruptiva Perstans Following Radiotherapy: Atypical Presentation of a Rare Condition.

Mastocytosis: Part II: Diagnosis and Management of Mastocytosis through a Multidisciplinary Lens.

Mastocytosis: Part I: Pathogenesis, Clinical Presentation and Classification.

Prevalence of myeloid gene alterations in paediatric cutaneous and systemic mastocytosis.

Treatment of indolent systemic mastocytosis with sarilumab is not supported in a randomized trial.

Different clearance of KITD816V mutation and tryptase levels after haematopoietic cell transplantation in patients with systemic mastocytosis with associated haematological neoplasm.

Telangiectatic Mastocytosis: If It Is Not Mastocytosis, What Is It? Comment on Brockow et al. Challenges in the Diagnosis of Cutaneous Mastocytosis. Diagnostics 2024, 14, 161.

Atypical presentation of Olmesartan-induced gastritis and enteropathy.

Basophil Activation Test: Bridging Allergy and Oncology for Diagnostic, Therapeutic and Prognostic Applications in AllergoOncology: An EAACI Position Paper.

Utility of tryptase genotyping in the screening, diagnosis, and management of systemic mastocytosis.

Laser Therapy for Cutaneous Mastocytosis: A Systematic Review.

Safety and efficacy of extended venom immunotherapy maintenance intervals in mastocytosis.

Sex differences in urinary mast cell mediators: Implications for diagnosing atopic and mast cell disorders.

New treatments for systemic mastocytosis in 2025.

Current and future therapeutics targeting mast cells in disease.

Hereditary alpha-tryptasemia - a potential cause of severe anaphylactic reactions and a modifier of mast cell diseases.

Characteristics and Therapeutic Strategies for Diffuse Cutaneous Mastocytosis.

Defining "Normal" basal serum tryptase levels: a context-dependent approach to improve diagnostics in systemic mastocytosis.

Cutaneous mastocytosis: diagnostic challenges and dietary influences.

Histamine metabolite to basal serum tryptase ratios in systemic mastocytosis and hereditary alpha tryptasemia using a validated LC-MS/MS approach.

Continued symptom and quality of life improvement with favorable safety shown with long-term avapritinib in indolent systemic mastocytosis.

Effectiveness of histamine receptor antagonists in the treatment of histamine-driven clinical symptoms: do we have a histamine or, better, an anti-histamine problem?