Raras
Buscar doenças, sintomas, genes...
Riquetsiose
ORPHA:102021CID-10 · A79DOENÇA RARA

Grupo de doenças infecciosas causadas por Rickettsia.

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Introdução

O que você precisa saber de cara

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Grupo de doenças infecciosas causadas por Rickettsia.

Publicações científicas
394 artigos
Último publicado: 2026 Feb 26
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SUS: Sem cobertura SUSScore: 0%
CID-10: A79
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Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🫃
Digestivo
7 sintomas
🧬
Pele e cabelo
5 sintomas
🩸
Sangue
5 sintomas
🧠
Neurológico
3 sintomas
🫁
Pulmão
3 sintomas
❤️
Coração
2 sintomas

+ 18 sintomas em outras categorias

Características mais comuns

Comportamento atípico
Esplenomegalia
Febre
Náusea
Dor abdominal
Cefaleia
47sintomas
Sem dados (47)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 47 características clínicas mais associadas, ordenadas por frequência.

Comportamento atípicoAtypical behavior
EsplenomegaliaSplenomegaly
FebreFever
NáuseaNausea
Dor abdominalAbdominal pain

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico394PubMed
Últimos 10 anos200publicações
Pico202134 papers
Linha do tempo
2026Hoje · 2026🧪 2006Primeiro ensaio clínico📈 2021Ano de pico
Publicações por ano (últimos 10 anos)

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Genética e causas

O que está alterado no DNA e como passa nas famílias

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Nenhum gene associado encontrado

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·Pré-clínico2
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 2 ensaios
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Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Riquetsiose

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Ensaios clínicos abertos e novidades científicas recentes

Pesquisa e ensaios clínicos

13 ensaios clínicos encontrados.

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Publicações mais relevantes

Timeline de publicações
154 papers (10 anos)
#1

Acute febrile illness surveillance using TaqMan Array Cards in two urban health facilities, Monrovia, Liberia, December 2018-March 2020.

PLoS neglected tropical diseases2026 Feb

Fever is a common symptom of infectious diseases including for those with epidemic potential. Beyond malaria, the causes of undifferentiated (i.e., non-respiratory, non-diarrheal) acute febrile illnesses are not well characterized in Liberia. From December 2018 through March 2020, we established two acute febrile illness (AFI) sentinel surveillance sites in urban Monrovia at Redemption Hospital and Star of the Sea Health Centre, health facilities that were among the first to have Ebola cases during the 2014-2015 West Africa epidemic. Enrolled AFI patients were two (2) years of age or greater, had a measured fever of ≥37.5oC or history of fever within the past week, and without a known cause of fever. A standardized survey was administered to collect demographic, clinical characteristics, and risk factors. Whole blood was taken, nucleic acid material was extracted and ran on TaqMan Array Cards (TAC), a real-time polymerase chain reaction (RT-PCR) testing platform for 28 pathogens. Data were analyzed using descriptive statistics, and multivariate regression models of any TAC detections stratified by site and age. We enrolled 1506 AFI patients, 1206 (80%) from Redemption Hospital and 300 (20%) from Star of the Sea. AFI patients were predominantly female (69%) and had a median (interquartile range) age of 18 (7-27) years. Among the 699 (46%) that were TAC positive, 627 were detected from Redemption Hospital and 72 were detected from Star of the Sea Health Centre. Overall Plasmodium spp. (malaria) (96%) were the majority of detections followed by dengue virus (2%), Streptococcus pneumoniae (2%), and Rickettsia spp. (1%). We detected 19 co-infections [malaria co-infections (84%) being the most common]. Two pathogens with epidemic potential, Neisseria meningitidis (detected at Star of the Sea Health Centre) and Lassa virus (detected at Redemption Hospital), were also found. Patients with non-malaria TAC detections (n = 29) were higher at Star of the Sea Health Centre than Redemption Hospital (4% versus 1% respectively, p < 0.05). In multivariate regression for those ages 15 years and older at Redemption Hospital (adjusting for sex, age, pregnancy status, education, occupation, any medication use, measured fever at enrollment, headache, abdominal pain, vomiting/nausea and joint pain), any medication use (aOR=0.6, 95% CI = 0.4-0.9), measured fever at enrollment (aOR=3.5, 95% CI = 1.1-12.0), headache (aOR=1.7, 95% CI = 1.1-2.6 were statistically significant with any TAC detection. In multivariate regression for those ages 2-14 years at Redemption Hospital (adjusting for sex, age, abdominal pain, cough, vomiting/nausea, runny nose, and any animal exposure), having abdominal pain (aOR=1.9, 95% CI = 1.3-2.8), vomiting/nausea (aOR=0.6, 95% CI = 0.4-1.0), and any animal exposure (aOR=1.5, 95% CI = 1.0-2.3) were statistically significant with any TAC detection. This is the first laboratory evidence of dengue and rickettsial disease in humans in Liberia. Liberia's incipient AFI platform was successful exploring causes of fever in emerging infections and detected circulating pathogens beyond malaria. AFI surveillance data can assist in the prioritization of public health diagnostic and clinical capabilities to prevent, detect, and respond to emerging infectious disease threats in Liberia.

#2

Targeted mutagenesis in Ehrlichia canis deleting the phage head-to-tail connector protein gene and its assessment as a vaccine candidate preventing canine ehrlichiosis.

Vaccine2026 Mar 16

Ehrlichia canis is primarily a Rhipicephalus sanguineus tick-borne rickettsial pathogen initially identified as causing canine monocytic ehrlichiosis, and human infections have also been reported in Venezuela, Mexico, and parts of Europe. It is of high importance to have a vaccine suitable in protecting the canine host, which will aid in lessening E. canis infections also in humans. Gene inactivation mutations in the phage head-to-tail connector protein genes (phtcp) from E. chaffeensis and A. marginale caused attenuated growth, and prior infection with the mutated bacteria induced protective immunity against wild-type bacterial infections in the natural hosts, independent of infection acquisition from blood-borne infection or tick-transmission. In the current study, we describe the development of targeted mutagenesis for the first time in E. canis genome and with a novel modification to avoid introducing antibiotic resistance cassettes to delete the phtcp ortholog from E. canis. The mutated E. canis was then assessed for its in vivo growth and the induction of host immunity exerted following the mutant infection aiding to protect against wild-type infection challenge in the canine host. We assessed systemic infection, hematological parameters, immune responses, and plasma cytokines following the mutant infection relative to uninfected dogs. Similarly, the assessments were carried out following wild-type pathogen infections in dogs with or without prior mutant infection challenges. The study demonstrates that prior infection of dogs with the mutant induces immunity to prevent infection establishment by wild-type E. canis. Similarly, the mutant infection resulted in clear biological differences compared to the wild-type infection. This study establishes that the molecular genetic methods are broadly applicable to pathogens belonging to the family Anaplasmataceae and that the modified live vaccines with functional defects in phtcp gene orthologs are valuable in reducing the diseases caused by the tick-borne rickettsial pathogens belong to Anaplasmataceae, including E. canis.

#3

Metagenomic sequencing identifies potential respiratory pathogens in PCR-negative subset of surveillance samples.

Scientific reports2026 Feb 16

Respiratory pathogens are a significant source of global morbidity, mortality, and economic burden, with the COVID-19 pandemic driving increased interest in and funding for respiratory disease surveillance. Syndromic panel multiplex nucleic acid amplification tests (NAATs) such as the BioFire Respiratory Panel (RP) are designed to identify the most common etiologic agents of respiratory illness. Untargeted metagenomic sequencing is a powerful tool for pathogen-agnostic detection, enabling the recovery of complete genomes for genomic epidemiology and variant tracking. In this study, we performed untargeted metagenomic sequencing of 305 samples previously negative by BioFire RP and SARS-CoV-2 testing and 26 samples that were previously positive by either of the diagnostic tests. A subset of 78 samples underwent probe-capture enrichment sequencing targeting human viruses. Using these methods, we identified human respiratory viruses in 16 of the 305 previously negative samples (5%). The most common viruses identified were Influenza C virus, Human Bocavirus, Rhinovirus A and C, and SARS-CoV-2. Consensus genomes were recovered for 14 viruses with > 90% coverage breadth, revealing closely related Bocavirus strains from neighboring counties and distinct Rhinovirus strains across samples. We also identified 21 samples with a single predominant bacterial or fungal species in the previous negative cohort. These findings underscore the challenges of identifying causal agents from multiplex NAAT-negative cases and highlight the utility of metagenomics for expanding the scope of pathogen surveillance.

#4

Epidemiological and clinical profiles of ocular involvement in rickettsiosis in southern Tunisia.

Journal francais d'ophtalmologie2026 Jan

The ocular manifestations of rickettsial diseases are polymorphic. The goal of our work was to characterize the ocular manifestations of rickettsial diseases and to determine the contribution of ophthalmic examination to the diagnosis. We conducted a retrospective descriptive analysis including consecutive patients with ocular involvement from confirmed rickettsial disease after ruling out other infectious or inflammatory etiologies. Demographic, clinical, multimodal imaging (fluorescein angiography, optical coherence tomography [OCT]), and therapeutic intervention data were systematically analyzed. This study included 24 patients with serologically confirmed rickettsial ocular involvement (mean age 40 years; range 16-67). Presentation with ophthalmologic symptoms occurred in 54.2% (n=13), demonstrating unilateral (58.4%, n=14) or bilateral (41.7%, n=10) ocular involvement, totaling 34 affected eyes. Posterior uveitis predominated (70.5%, 24 eyes), while other significant ophthalmologic signs included fine keratic precipitates (17.6%, 6 eyes), retinitis (64.7%, 22 eyes), retinal vasculitis (20.6%, 7 eyes), and neuroretinitis (8.8%, 3 eyes). Systemic manifestations featured febrile episodes with cutaneous eruptions in 70.8% (n=17). All patients received antibiotic treatment. Oral corticosteroid therapy was added in 12.5% (n=3). Complete resolution of inflammation occurred after a mean follow-up of 3 months. In our series, ocular manifestations in rickettsial infections presented symptomatically in only half of cases, with retinitis and retinal vasculitis emerging as the predominant findings. These observations highlight the importance of systematic posterior segment examination in suspected rickettsial cases to facilitate prompt diagnosis and therapeutic intervention.

#5

Pneumonia with no eschar: an atypical presentation of rickettsial disease.

BMJ case reports2025 Dec 03

A middle-aged male construction worker presented with a 7-day history of fever, night sweats and malaise, unresponsive to oral cefuroxime. He developed pale stools and dark urine but denied abdominal pain or neurological symptoms. Examination revealed mild jaundice with stable vital signs and no focal findings. Laboratory tests showed markedly elevated C-reactive protein, thrombocytopenia and significantly deranged liver enzymes. Extensive infectious workup was negative except for a positive PCR for Rickettsia species. Imaging revealed a right upper lobe consolidation on CT, though chest X-ray was initially normal. He was empirically treated with doxycycline before confirmation of rickettsial infection, based on the clinical picture. The patient's symptoms and liver function improved with doxycycline, supporting the diagnosis of a systemic rickettsial illness with hepatic and pulmonary involvement. This case is notable for the rare pulmonary involvement in rickettsial infection along with the absence of the typical rickettsial rash or eschar, both of which highlight the diagnostic challenge in this case.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC100 artigos no totalmostrando 198

2026

Targeted mutagenesis in Ehrlichia canis deleting the phage head-to-tail connector protein gene and its assessment as a vaccine candidate preventing canine ehrlichiosis.

Vaccine
2026

Metagenomic sequencing identifies potential respiratory pathogens in PCR-negative subset of surveillance samples.

Scientific reports
2026

Acute febrile illness surveillance using TaqMan Array Cards in two urban health facilities, Monrovia, Liberia, December 2018-March 2020.

PLoS neglected tropical diseases
2025

Geographic shift of Japanese spotted fever and diagnostic overshadowing by COVID-19 testing: A genetically confirmed northernmost case.

IDCases
2026

Epidemiological and clinical profiles of ocular involvement in rickettsiosis in southern Tunisia.

Journal francais d'ophtalmologie
2025

Pneumonia with no eschar: an atypical presentation of rickettsial disease.

BMJ case reports
2025

Genomic and epidemiologic characteristics of SARS-CoV-2 persistent infections in California, January 2021 - July 2023.

PLoS pathogens
2025

Silent Threat: Multi-Organ Failure in Neonatal Scrub Typhus Without Traditional Markers.

Clinical case reports
2025

Epidemiologic and Environmental Investigations of Reported Hantavirus Cases Inform Exposure Risk in California, 1993-2020.

The American journal of tropical medicine and hygiene
2025

Clinical presentation of seasonal respiratory viruses in California, May 2020-July 2022.

Annals of epidemiology
2025

Classifying Eschar Morphologies: Enhancing Early Diagnosis of Scrub Typhus.

Journal of Korean medical science
2025

Rickettsioses Seropositivity in Malaysia: A Six-Year Trend, 2016-2021.

Tropical medicine and infectious disease
2025

Beyond the Fever: A Serial Report on Moderate to Severe Murine Typhus Cases and Diagnostic Hurdles in Indonesia.

Tropical medicine and infectious disease
2025

Clade I or clade II? Targeting essential viral genes to differentiate monkeypox virus clades by multiplex real-time PCR.

Frontiers in public health
2025

Evaluating the Effectiveness of NOACs and LMWH in Reducing Mortality in Critically Ill Patients With COVID-19.

Journal of medical virology
2025

A Systematic Review and Meta-analysis of Scrub Typhus and its Association with Liver Disease.

Journal of global infectious diseases
2025

Epidemiological and clinical predictors of murine typhus in hospitalized patients in central israel: association with urban construction.

European journal of clinical microbiology &amp; infectious diseases : official publication of the European Society of Clinical Microbiology
2025

Differential immunity induced by Omicron sublineages in naïve and vaccine breakthrough infections.

Scientific reports
2025

Respiratory manifestations of rickettsial disease in tropical Australia; Clinical course and implications for patient management.

Acta tropica
2025

Bilateral acute multifocal retinitis and retinal vasculitis secondary to Rickettsia typhi infection.

Journal of ophthalmic inflammation and infection
2025

Validation of Clinical RGA Score in Diagnosis of Scrub Typhus at 2nd Tier Hospital of West Bengal, India.

Mymensingh medical journal : MMJ
2025

Clinico-epidemiological and immunological characteristics of rickettsioses in a Sri Lankan patient cohort 2018-2023.

BMC infectious diseases
2025

Temporal trends in diagnostic evolutions for rickettsial diseases including scrub typhus: a bibliometric study.

Pathogens and global health
2025

SARS-CoV-2 Omicron subvariant genomic variation associations with immune evasion in Northern California: A retrospective cohort study.

PloS one
2025

Rickettsial Pathogens in Dogs and Ticks During an Epidemic of Rocky Mountain Spotted Fever in Ensenada, Baja California, México.

The American journal of tropical medicine and hygiene
2025

First Clade Ib Monkeypox Virus Infection Reported in the Americas - California, November 2024.

MMWR. Morbidity and mortality weekly report
2025

A wolf at the door: the ecology, epidemiology, and emergence of community- and urban-level Rocky Mountain spotted fever in the Americas.

American journal of veterinary research
2025

Core-genome guided novel therapeutic targets identification and chimeric vaccine designing against Rickettsia rickettsii.

Scientific reports
2024

Epidemiology and clinical characteristics of Mediterranean spotted fever suspects in a university hospital, Tunisia, 2000-2020.

Epidemiology and infection
2024

Ticked Off: A Case of Disappearing Cell Lines.

Cureus
2024

"Is it time to initiate scrub typhus surveillance in Karnataka?"-Lessons from a seroprevalence survey in a rural district.

Journal of family medicine and primary care
2024

Laboratory validation of a clinical metagenomic next-generation sequencing assay for respiratory virus detection and discovery.

Nature communications
2025

Clinical Characteristics and Risk Factors for Severe Japanese Spotted Fever: A Retrospective Multicenter Study in the Nagasaki Prefecture, Western Japan.

Japanese journal of infectious diseases
2024

Orientia tsutsugamushi infection reduces host gluconeogenic but not glycolytic substrates.

Infection and immunity
2024

Prevalence, Clinico-Laboratory Features and Outcomes of Paediatric Scrub Typhus Cases in a Tertiary Care Centre in Eastern India: A prospective observational study.

Sultan Qaboos University medical journal
2024

Sea-fan retinal neovascularization associated with rickettsial retinitis: a case report.

BMC ophthalmology
2024

Emergence of Recombinant SARS-CoV-2 Variants in California from 2020 to 2022.

Viruses
2024

Human Orthohantavirus disease prevalence and genotype distribution in the U.S., 2008-2020: a retrospective observational study.

Lancet regional health. Americas
2024

Duplex Reverse-Transcription Real-Time Polymerase Chain Reaction Assay Targeting 23S rRNA Single Nucleotide Polymorphisms for the Detection of Flea-Borne Rickettsioses.

The American journal of tropical medicine and hygiene
2024

Knowledge, attitudes, and practices (KAPs) regarding tick-borne rickettsial disease among medical staff in endemic areas of China.

PeerJ
2024

Rocky Mountain Spotted Fever Mimicking Multisystem Inflammatory Syndrome in Hospitalized Children, Sonora, Mexico.

Emerging infectious diseases
2024

Human rickettsial infections in India - A review.

Journal of vector borne diseases
2024

Metagenomic analysis of individual mosquito viromes reveals the geographical patterns and drivers of viral diversity.

Nature ecology &amp; evolution
2024

Neurological manifestation of Brazilian spotted fever in childhood.

Revista do Instituto de Medicina Tropical de Sao Paulo
2024

Epidemiology of Murine Typhus in Taiwan from 2013 to 2020.

The American journal of tropical medicine and hygiene
2024

Severe murine typhus complicated by multiple organ dysfunctions: A case report.

Caspian journal of internal medicine
2024

Diagnosing and reintegrating traceability of infectious diseases via metagenomic next-generation sequencing: Study of a severe case of Rickettsia japonica infection.

Infectious medicine
2024

The emergence of Rocky Mountain spotted fever in the southwestern United States and northern Mexico requires a binational One Health approach.

Journal of the American Veterinary Medical Association
2024

Neurological Manifestations of Scrub Typhus Infection in Pediatric Patient: A Case Report From Tertiary Care Hospital in Central India.

Cureus
2024

Acral palpable purpura with rapidly progressing multiorgan involvement.

JAAD case reports
2024

A case of neonatal tsutsugamushi disease diagnosed with the aid of rickettsial macrogenomic detection.

BMC pediatrics
2024

Implementing the WHO AWaRe antibiotic book guidance in lower-resource settings: the case of the Lao PDR.

JAC-antimicrobial resistance
2023

Seroprevalence of Rickettsial disease: A population-based survey from kashmir valley, North India.

Indian journal of public health
2024

Surveillance of ticks on a tropical island with introduced ungulates.

Journal of medical entomology
2023

Metagenomic analysis of individual mosquitos reveals the ecology of insect viruses.

bioRxiv : the preprint server for biology
2023

Rickettsial Disease Outbreak, Mexico, 2022.

Emerging infectious diseases
2023

Shadow of a Pandemic: Persistence of Prenatal SARS-CoV-2 Antibodies in Newborn Blood Spots.

International journal of neonatal screening
2023

Perception of risk among children: Exploring the risk of TB-rickettsial disease based on the children's drawing pictures in a Mayan community of Yucatan.

Health promotion perspectives
2023

Detection of Orientia spp. Bacteria in Field-Collected Free-Living Eutrombicula Chigger Mites, United States.

Emerging infectious diseases
2023

Individual bat virome analysis reveals co-infection and spillover among bats and virus zoonotic potential.

Nature communications
2024

Optical Coherence Tomography and Optical Coherence Tomography Angiography in Neglected Diseases.

Ocular immunology and inflammation
2023

Severe Acute Respiratory Syndrome Coronavirus 2 Delta Variant Genomic Variation Associated With Breakthrough Infection in Northern California: A Retrospective Cohort Study.

The Journal of infectious diseases
2022

The seasonality of infections in tropical Far North Queensland, Australia: A 21-year retrospective evaluation of the seasonal patterns of six endemic pathogens.

PLOS global public health
2023

Association of scrub typhus with incidence of dementia: a nationwide population-based cohort study in Korea.

BMC infectious diseases
2022

Lessons Learned From a Case of Behcet's Disease Presenting With Fever and Life-Threatening Venous Thromboembolism.

Cureus
2022

Rickettsial disease: An underestimated cause of posterior uveitis.

Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
2023

The potential of Rhipicephalus microplus as a vector of Ehrlichia ruminantium in West Africa.

Ticks and tick-borne diseases
2023

Rickettsia felis is an emerging human pathogen associated with cat fleas: A review of findings in Taiwan.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
2023

Japanese spotted fever with post-infectious encephalitis.

IDCases
2022

Multiple Mutations Associated with Emergent Variants Can Be Detected as Low-Frequency Mutations in Early SARS-CoV-2 Pandemic Clinical Samples.

Viruses
2022

An Unsuspected Case of Rocky Mountain Spotted Fever: A Lesson to Keep a Broad Differential.

Journal of investigative medicine high impact case reports
2022

Evaluation of co-circulating pathogens and microbiome from COVID-19 infections.

PloS one
2022

Recent Threat of Scrub Typhus in India: A Narrative Review.

Cureus
2022

Co-effects of global climatic dynamics and local climatic factors on scrub typhus in mainland China based on a nine-year time-frequency analysis.

One health (Amsterdam, Netherlands)
2022

Survey on the Presence of Equine Tick-Borne Rickettsial Infections in Southcentral United States.

Journal of equine veterinary science
2022

Neutralizing Immunity Induced Against the Omicron BA.1 and BA.2 Variants in Vaccine Breakthrough Infections.

The Journal of infectious diseases
2022

Clustered Incidence of Leukocytoclastic Vasculitis and Purpura Fulminans: A Case Series of a Rare Dermatological Manifestation of Rickettsial Disease.

Cureus
2022

Epidemiologic and environmental characterization of the Re-emergence of St. Louis Encephalitis Virus in California, 2015-2020.

PLoS neglected tropical diseases
2022

Rickettsia conorii infection with fatal complication.

Autopsy &amp; case reports
2022

Scrub Typhus: A Spatial and Temporal Analysis from South India.

Journal of tropical pediatrics
2022

Diversity and prevalence of ticks in the goats in lowland Nepal.

Annals of parasitology
2022

The first study on the seroprevalence of Anaplasma spp. in small ruminants and assessment of associated risk factors in North Egypt.

Veterinary world
2022

Systematic Surveillance of Rickettsial Diseases in 27 Hospitals from 26 Provinces throughout Vietnam.

Tropical medicine and infectious disease
2022

Molecular detection of Orientia tsutsugamushi strains circulating in Nagaland.

Indian journal of medical microbiology
2022

Molecular epidemiology, phylogenetic analysis and risk assessment of Anaplasma marginale from naturally infected bovines of Punjab (India).

Acta tropica
2022

Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants.

Cell
2021

Scrub typhus: An under-reported and emerging threat - hospital based study from central and eastern Uttar Pradesh, India.

Journal of vector borne diseases
2022

Nationwide Seroprevalence of Scrub Typhus, Typhus, and Spotted Fever in Young Thai Men.

The American journal of tropical medicine and hygiene
2022

A multitope SARS-CoV-2 vaccine provides long-lasting B cell and T cell immunity against Delta and Omicron variants.

The Journal of clinical investigation
2022

Hand, foot, and mouth disease in adults caused by Coxsackievirus B1-B6.

Anais brasileiros de dermatologia
2022

A time-series meta-transcriptomic analysis reveals the seasonal, host, and gender structure of mosquito viromes.

Virus evolution
2021

The expanding spectrum of disease caused by the Lone Star Tick, Amblyomma americanum.

Le infezioni in medicina
2022

Rickettsiosis with Pleural Effusion: A Systematic Review with a Focus on Rickettsiosis in Italy.

Tropical medicine and infectious disease
2022

Profile of Neurological Manifestations in Children Presenting with Rickettsial Disease.

Indian pediatrics
2022

Predominance of antibody-resistant SARS-CoV-2 variants in vaccine breakthrough cases from the San Francisco Bay Area, California.

Nature microbiology
2022

Comparative evaluation of serological tests used for the diagnosis of rickettsial diseases prevalent in the temperate region of North India.

Indian journal of medical microbiology
2021

Halved Incidence of Scrub Typhus after Travel Restrictions to Confine a Surge of COVID-19 in Taiwan.

Pathogens (Basel, Switzerland)
2021

Ocular Manifestations of Emerging Arthropod-Borne Infectious Diseases.

Journal of current ophthalmology
2021

The Applicability of Commonly Used Severity of Illness Scores to Tropical Infections in Australia.

The American journal of tropical medicine and hygiene
2021

Seroprevalence trends of Scrub typhus among the febrile patients of Northern India: A prospective cross-sectional study.

Journal of family medicine and primary care
2021

Confirmation of Rickettsia conorii Subspecies indica Infection by Next-Generation Sequencing, Shandong, China.

Emerging infectious diseases
2022

A severe case of Israeli spotted fever with pleural effusion in Italy.

Infection
2021

Delayed positive COVID19 nasopharyngeal test, a case study with clinical and pathological correlation.

BMC pulmonary medicine
2021

Establishment of a Rhesus Macaque Model for Scrub Typhus Transmission: Pilot Study to Evaluate the Minimal Orientia tsutsugamushi Transmission Time by Leptotrombidium chiangraiensis Chiggers.

Pathogens (Basel, Switzerland)
2021

Rickettsial Infections among the Undifferentiated Febrile Patients Attending a Tertiary Care Teaching Hospital of Northern India: A Longitudinal Study.

Infection &amp; chemotherapy
2021

First seroprevalence report of scrub typhus from the tribal belts of the Nilgiris district, Tamil Nadu, India.

The Indian journal of medical research
2021

Scrub typhus and antibiotic-resistant Orientia tsutsugamushi.

Expert review of anti-infective therapy
2021

Assessing scrub typhus and rickettsioses transmission risks in the Chiang Rai province of northern Thailand.

Travel medicine and infectious disease
2021

Clinical and biochemical profile of scrub typhus patients at a tertiary care hospital in Northern India.

Journal of family medicine and primary care
2021

Prevalence of Rickettsia rickettsii in Ticks: Systematic Review and Meta-Analysis.

Vector borne and zoonotic diseases (Larchmont, N.Y.)
2021

Commentary: Posterior segment manifestations of rickettsial disease.

Indian journal of ophthalmology
2021

Ocular manifestation of rickettsial disease in South Indian population.

Indian journal of ophthalmology
2021

Introduction, Transmission Dynamics, and Fate of Early Severe Acute Respiratory Syndrome Coronavirus 2 Lineages in Santa Clara County, California.

The Journal of infectious diseases
2021

Effect of Temperature on Host Preference in Two Lineages of the Brown Dog Tick, Rhipicephalus sanguineus.

The American journal of tropical medicine and hygiene
2021

Abducens nerve palsy with associated retinal involvement secondary to rickettsia typhi infection.

Journal of ophthalmic inflammation and infection
2021

International Rickettsia Disease Surveillance: An Example of Cooperative Research to Increase Laboratory Capability and Capacity for Risk Assessment of Rickettsial Outbreaks Worldwide.

Frontiers in medicine
2021

Rickettsial neuroretinitis: A report of 2 cases.

American journal of ophthalmology case reports
2021

Seroprevalence of scrub typhus, murine typhus and spotted fever groups in North Korean refugees.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2021

A diagnostic host response biosignature for COVID-19 from RNA profiling of nasal swabs and blood.

Science advances
2021

Molecular Epidemiology of Measles in California, United States-2019.

The Journal of infectious diseases
2021

Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA): 2020 Guideline on Diagnosis and Management of Babesiosis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
2021

Timely intervention and control of a novel coronavirus (COVID-19) outbreak at a large skilled nursing facility-San Francisco, California, 2020.

Infection control and hospital epidemiology
2021

Characteristics of in vitro infection of human monocytes, by Rickettsia helvetica.

Microbes and infection
2021

Exploring the Niche of Rickettsia montanensis (Rickettsiales: Rickettsiaceae) Infection of the American Dog Tick (Acari: Ixodidae), Using Multiple Species Distribution Model Approaches.

Journal of medical entomology
2020

A Brief History of the Major Rickettsioses in the Asia-Australia-Pacific Region: A Capstone Review for the Special Issue of TMID.

Tropical medicine and infectious disease
2021

Prompt defervescence after initiation of treatment for rickettsial infections - time to dispense with the dogma?

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2020

Clinical signs, prevalence, and hematobiochemical profiles associated with Anaplasma infections in sheep of North Iraq.

Veterinary world
2020

Tickbite-associated chronic pruritic lesions in an Afro-descendant population in the Cauca Department, Colombia. I. Clinical features and impact on health.

International journal of dermatology
2020

Assessing human exposure to spotted fever and typhus group rickettsiae in Ontario, Canada (2013-2018): a retrospective, cross-sectional study.

BMC infectious diseases
2021

Acute Fulminant Cerebral Edema: A Newly Recognized Phenotype in Children With Suspected Encephalitis.

Journal of the Pediatric Infectious Diseases Society
2021

Spotted Fever Group Rickettsiae among Children with Acute Febrile Illness, in Gorakhpur, India.

Journal of tropical pediatrics
2020

Evidence of Q Fever and Rickettsial Disease in Chile.

Tropical medicine and infectious disease
2020

Rapid Detection of 2019 Novel Coronavirus SARS-CoV-2 Using a CRISPR-based DETECTR Lateral Flow Assay.

medRxiv : the preprint server for health sciences
2020

Cerebellitis as a rare manifestation of scrub typhus fever.

BMJ case reports
2020

Disease Ecology of Rickettsial Species: A Data Science Approach.

Tropical medicine and infectious disease
2020

Spotted fever rickettsiosis presenting with bilateral anterior uveitis and retinitis: A case report.

Journal of family medicine and primary care
2020

CRISPR-Cas12-based detection of SARS-CoV-2.

Nature biotechnology
2020

The estimated burden of scrub typhus in Thailand from national surveillance data (2003-2018).

PLoS neglected tropical diseases
2020

Scrub Typhus: Historic Perspective and Current Status of the Worldwide Presence of Orientia Species.

Tropical medicine and infectious disease
2020

Human Rickettsia felis infection in India.

Journal of vector borne diseases
2020

Probable African Tick Bite Fever in the United States.

The Yale journal of biology and medicine
2020

Domestic dogs are mammalian reservoirs for the emerging zoonosis flea-borne spotted fever, caused by Rickettsia felis.

Scientific reports
2021

Searching and Finding the Hidden Treasure: A Retrospective Analysis of Rickettsial Disease Among Dutch International Travelers.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
2020

Author Correction: Metagenomic sequencing with spiked primer enrichment for viral diagnostics and genomic surveillance.

Nature microbiology
2020

Metagenomic sequencing with spiked primer enrichment for viral diagnostics and genomic surveillance.

Nature microbiology
2020

Evaluation of oxidative stress in caprine anaplasmosis and effect of vitamin E-selenium in monitoring oxidative stress.

Tropical animal health and production
2020

Real-time PCR assay with an endogenous internal amplification control for detection and quantification of Anaplasma marginale in bovine blood.

Ticks and tick-borne diseases
2019

Human Parasitism by Amblyomma parkeri Ticks Infected with Candidatus Rickettsia paranaensis, Brazil.

Emerging infectious diseases
2019

Nearly Complete Genome Sequence of an Echovirus 30 Strain from a Cluster of Aseptic Meningitis Cases in California, September 2017.

Microbiology resource announcements
2019

Seroprevalence of typhus group rickettsial infections in the north-east region of India.

The Indian journal of medical research
2019

Molecular characterization of Orientia tsutsugamushi causing scrub typhus among febrile patients in north-central Bangladesh.

New microbes and new infections
2019

Computational selection of minimum length groESL operon required for Anaplasma species attribution and strain diversity analysis.

Molecular and cellular probes
2019

High Seroprevalence of Mycoplasma pneumoniae and Chlamydia pneumoniae among Scrub Typhus Patients in South Korea.

The American journal of tropical medicine and hygiene
2019

Patients with laboratory evidence of West Nile virus disease without reported fever.

Epidemiology and infection
2019

The epidemiology and clinical features of rickettsial diseases in North Queensland, Australia: Implications for patient identification and management.

PLoS neglected tropical diseases
2020

Rotavirus Vaccination Coverage During a Rotavirus Outbreak Resulting in a Fatality at a Subacute Care Facility.

Journal of the Pediatric Infectious Diseases Society
2019

New and old hotspots for rickettsial spotted fever acquired in Tasmania, 2012-2017.

Australian and New Zealand journal of public health
2019

New Subgenotyping and Consensus Real-Time Reverse Transcription-PCR Assays for Hepatitis A Outbreak Surveillance.

Journal of clinical microbiology
2019

A biosafety level-2 dose-dependent lethal mouse model of spotted fever rickettsiosis: Rickettsia parkeri Atlantic Rainforest strain.

PLoS neglected tropical diseases
2019

Emerging Roles of Autophagy and Inflammasome in Ehrlichiosis.

Frontiers in immunology
2019

Expanded Molecular Testing on Patients with Suspected West Nile Virus Disease.

Vector borne and zoonotic diseases (Larchmont, N.Y.)
2019

A Tale of Two Valleys: Disparity in Sin Nombre Virus Antibody Reactivity Between Neighboring Mojave Desert Communities.

Vector borne and zoonotic diseases (Larchmont, N.Y.)
2019

Purpuric rash and fever among hospitalized children aged 0-18 years: Comparison between clinical, laboratory, therapeutic and outcome features of patients with bacterial versus viral etiology.

Pediatrics and neonatology
2019

Evaluation of Th1 and Th2 immune response in clinical and sub-clinical scrub typhus infection.

Human immunology
2019

Clinical characteristics and effective treatments of scrub typhus-associated hemophagocytic lymphohistiocytosis in children.

Journal of advanced research
2019

Inflammatory arthritis: a unique presentation of human anaplasmosis.

Clinical rheumatology
2018

Ocular manifestations of Rickettsia conorii in South India.

Indian journal of ophthalmology
2018

Acute multifocal retinitis: a retrospective review of 35 cases.

Journal of ophthalmic inflammation and infection
2018

Genome Sequences of Rhinovirus Genotype C56 Detected in Three Patients with Acute Respiratory Illness, California, 2016 to 2017.

Microbiology resource announcements
2019

Vector Tick Transmission Model of Spotted Fever Rickettsiosis.

The American journal of pathology
2018

Scrub Typhus: No Longer Restricted to the Tsutsugamushi Triangle.

Tropical medicine and infectious disease
2019

Mediterranean spotted fever rickettsiosis in Italy, 2001-2015: Spatio-temporal distribution based on hospitalization records.

Ticks and tick-borne diseases
2018

Scrub Typhus: Seven-Year Experience and Literature Review.

Journal of acute medicine
2018

Human parasitism and toxicosis by Ornithodoros rietcorreai (Acari: Argasidae) in an urban area of Northeastern Brazil.

Ticks and tick-borne diseases
2018

A 2015 outbreak of flea-borne rickettsiosis in San Gabriel Valley, Los Angeles County, California.

PLoS neglected tropical diseases
2018

Genetic diversity of Orientia tsutsugamushi strains circulating in Northeast India.

Transactions of the Royal Society of Tropical Medicine and Hygiene
2018

Detection and molecular characterisation of Ehrlichia canis in naturally infected dogs in South West Nigeria.

Acta veterinaria Hungarica
2018

Rickettsial Illnesses as Important Causes of Febrile Illness in Chittagong, Bangladesh.

Emerging infectious diseases
2018

Under-diagnosis of rickettsial disease in clinical practice: A systematic review.

Travel medicine and infectious disease
2018

Whole-Genome Sequence of Human Rhinovirus C47, Isolated from an Adult Respiratory Illness Outbreak in Butte County, California, 2017.

Genome announcements
2018

Confirming Rickettsia rickettsii as the etiological agent of lethal spotted fever group rickettsiosis in human patients from Espírito Santo state, Brazil.

Ticks and tick-borne diseases
2017

Canine Monocytic Ehrlichiosis among working dogs of organised kennels in India: A comprehensive analyses of clinico-pathology, serological and molecular epidemiological approach.

Preventive veterinary medicine
2018

A Severe Case of Murine Typhus Presenting With Anemia and Severe Thrombocytopenia.

Journal of pediatric hematology/oncology
2017

Kikuchi-Fujimoto disease: an unusual presentation of meningitis in a returning traveller.

BMJ case reports
2017

Spatio-temporal variations and genetic diversity of Anaplasma spp. in cattle from the North of Tunisia.

Veterinary microbiology
2017

Complete Genome Sequences of Mumps and Measles Virus Isolates from Three States in the United States.

Genome announcements
2017

Evaluation of a Spotted Fever Group Rickettsia Public Health Surveillance System in Tennessee.

The American journal of tropical medicine and hygiene
2017

Acute-phase diagnosis of murine and scrub typhus in Belgian travelers by polymerase chain reaction: a case report.

BMC infectious diseases
2017

Subacute Sclerosing Panencephalitis: The Devastating Measles Complication That Might Be More Common Than Previously Estimated.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
2016

[Late diagnosis of fatal invasive rickettsial disease in the Intensive Care Unit].

The Pan African medical journal
2017

Predictive Factors for Fatal Tick-Borne Spotted Fever in Brazil.

Zoonoses and public health
2017

Rickettsia felis Infection in Febrile Children, Ghana.

The American journal of tropical medicine and hygiene
2017

Molecular detection of Rickettsia species in ticks collected from the southwestern provinces of the Republic of Korea.

Parasites &amp; vectors
2017

Progress towards Rapid Detection of Measles Vaccine Strains: a Tool To Inform Public Health Interventions.

Journal of clinical microbiology
2016

Prevalence of Rickettsia spp. in Ticks and Serological and Clinical Outcomes in Tick-Bitten Individuals in Sweden and on the Åland Islands.

PloS one
2016

An update on the epidemiological situation of spotted fever in Brazil.

The journal of venomous animals and toxins including tropical diseases
2016

Scrub typhus and spotted fever among hospitalised children in South India: Clinical profile and serological epidemiology.

Indian journal of medical microbiology
2016

Rickettsial Disease in the Peruvian Amazon Basin.

PLoS neglected tropical diseases

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Doenças relacionadas

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Acute febrile illness surveillance using TaqMan Array Cards in two urban health facilities, Monrovia, Liberia, December 2018-March 2020.
    PLoS neglected tropical diseases· 2026· PMID 41662363mais citado
  2. Targeted mutagenesis in Ehrlichia canis deleting the phage head-to-tail connector protein gene and its assessment as a vaccine candidate preventing canine ehrlichiosis.
    Vaccine· 2026· PMID 41844092mais citado
  3. Metagenomic sequencing identifies potential respiratory pathogens in PCR-negative subset of surveillance samples.
    Scientific reports· 2026· PMID 41698961mais citado
  4. Epidemiological and clinical profiles of ocular involvement in rickettsiosis in southern Tunisia.
    Journal francais d'ophtalmologie· 2026· PMID 41443005mais citado
  5. Pneumonia with no eschar: an atypical presentation of rickettsial disease.
    BMJ case reports· 2025· PMID 41338894mais citado
  6. Subclinical Cardiac Disturbances After Rickettsia spp. Infection in an Endemic Region of Mexico.
    Trop Med Infect Dis· 2026· PMID 41893401recente
  7. Geographic shift of Japanese spotted fever and diagnostic overshadowing by COVID-19 testing: A genetically confirmed northernmost case.
    IDCases· 2025· PMID 41473481recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:102021(Orphanet)
  2. MONDO:0006956(MONDO)
  3. GARD:19827(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Artigo Wikipedia(Wikipedia)
  6. Q646664(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

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