A brucelose é uma infecção bacteriana que passa de animais para pessoas. Isso acontece principalmente ao consumir laticínios não pasteurizados (que não foram aquecidos para matar as bactérias) ou pelo contato com produtos de animais contaminados ou com os próprios animais doentes. Os animais mais comumente infectados incluem ovelhas, gado, cabras, porcos e cachorros. A brucelose pode causar uma série de sinais e sintomas, e alguns deles podem durar bastante ou retornar. Os primeiros sintomas podem ser febre, suores, mal-estar geral, falta de apetite, dor de cabeça, cansaço e/ou dores nos músculos, nas juntas e/ou nas costas. Sintomas que podem durar muito tempo ou retornar incluem febre que vai e volta, artrite (inflamação nas juntas), inchaço no testículo e na bolsa escrotal, inchaço do coração (chamado endocardite), problemas no sistema nervoso (em até 5% dos casos), cansaço crônico, depressão e/ou inchaço do fígado ou do baço. Pessoas que trabalham ou vivem em ambientes onde há maior risco de entrar em contato com a bactéria têm um risco maior de contrair a infecção. A brucelose é tratada com antibióticos. A recuperação pode levar de algumas semanas a vários meses, e é comum que os sintomas retornem (recidivas). A morte por brucelose é rara, ocorrendo em no máximo 2% dos casos.
Introdução
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A brucelose é uma infecção bacteriana que passa de animais para pessoas. Isso acontece principalmente ao consumir laticínios não pasteurizados (que não foram aquecidos para matar as bactérias) ou pelo contato com produtos de animais contaminados ou com os próprios animais doentes. Os animais mais comumente infectados incluem ovelhas, gado, cabras, porcos e cachorros. A brucelose pode causar uma série de sinais e sintomas, e alguns deles podem durar bastante ou retornar. Os primeiros sintomas podem ser febre, suores, mal-estar geral, falta de apetite, dor de cabeça, cansaço e/ou dores nos músculos, nas juntas e/ou nas costas. Sintomas que podem durar muito tempo ou retornar incluem febre que vai e volta, artrite (inflamação nas juntas), inchaço no testículo e na bolsa escrotal, inchaço do coração (chamado endocardite), problemas no sistema nervoso (em até 5% dos casos), cansaço crônico, depressão e/ou inchaço do fígado ou do baço. Pessoas que trabalham ou vivem em ambientes onde há maior risco de entrar em contato com a bactéria têm um risco maior de contrair a infecção. A brucelose é tratada com antibióticos. A recuperação pode levar de algumas semanas a vários meses, e é comum que os sintomas retornem (recidivas). A morte por brucelose é rara, ocorrendo em no máximo 2% dos casos.
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
1/2k
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Sinais e sintomas
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Os sintomas variam de pessoa para pessoa. Abaixo estão as 80 características clínicas mais associadas, ordenadas por frequência.
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Brucella abortus and public health risk: Prevalence in milk sold at open markets in Cameroon.
Um estudo nos Camarões confirmou a presença de *Brucella abortus* no leite vendido em mercados abertos, revelando um risco direto e anteriormente não identificado de brucelose para a saúde pública geral. Aproximadamente 1.3% das amostras de leite continham a bactéria viva, impulsionado por práticas de comerciantes que misturam e raramente fervem o leite, resultando na exposição semanal de centenas de pessoas. Este achado é crucial para médicos, que devem considerar a brucelose em casos de febre de origem desconhecida, e para pacientes, que devem obrigatoriamente ferver todo o leite antes do consumo para prevenir a infecção.
🇧🇷 traduzidoHuman brucellosis in pregnancy in western Uganda: High seroprevalence and health risk factors identified in a cross-sectional study.
Este estudo em Uganda revelou uma alta prevalência de brucelose (14%) em gestantes, uma zoonose que pode causar anemia, aborto espontâneo e parto prematuro. Os principais fatores de risco identificados foram o consumo de leite fresco ou carne malpassada, o contato frequente com esterco animal e a criação de gado em casa. Para pacientes e médicos, é crucial integrar o rastreamento de brucelose na rotina pré-natal e promover a pasteurização do leite, o preparo seguro da carne e melhorias na higiene para reduzir infecções maternas e complicações na gravidez.
🇧🇷 traduzidoASAP1 gene InDel variants are associated with enhanced goat resistance against Brucella infection.
Este estudo em cabras identificou que variantes genéticas específicas (P2 e P7) e certos haplótipos do gene ASAP1 estão associadas à resistência ou suscetibilidade à infecção por Brucella. Cabras com os haplótipos resistentes (Hap3 e Hap5) demonstraram maior expressão do gene ASAP1 e uma resposta inflamatória mais acelerada e robusta contra a infecção. Esses achados fornecem uma base teórica para o melhoramento genético de cabras, visando criar populações mais resistentes à brucelose e, consequentemente, reduzir a prevalência da doença em animais e o risco de transmissão para humanos.
🇧🇷 traduzidoSocioeconomic drivers of human Brucellosis in Ningxia, China: A one health and spatiotemporal analysis for targeted intervention.
Este estudo em Ningxia, China, revelou um aumento alarmante de 167 vezes na incidência de brucelose humana entre 2007 e 2022, com focos de alto risco persistentes em 11 condados orientais. Os principais impulsionadores são fatores relacionados à pecuária (rebanhos de ovinos e bovinos), com efeitos de risco que podem se manifestar anos após a exposição, enquanto um maior desenvolvimento econômico regional mostrou associação imediata com menor risco. Para médicos e pacientes, isso sublinha a importância de medidas de saúde pública veterinária focadas em áreas de risco e do aproveitamento do desenvolvimento econômico para fortalecer a prevenção e o controle a longo prazo.
🇧🇷 traduzidoSeroprevalence and Associated Risk Factors of Brucellosis in Backyard Dairy Cattle in the Western Buffer Zone of Chitwan National Park, Nepal.
Este estudo detectou brucelose bovina, uma doença zoonótica com potencial de transmissão para humanos, em 1.6% do gado leiteiro de criação doméstica em uma importante região produtora de leite no Nepal. Para pacientes e médicos, isso significa um risco potencial de infecção para humanos através de produtos lácteos não pasteurizados, sublinhando a necessidade de maior conscientização sobre a doença e sua epidemiologia para proteger a saúde pública.
🇧🇷 traduzidoPublicações recentes
One health perspectives on the epidemiological features and changing incidence of natural focus and vector-borne infectious diseases in China: An observational trend study.
Construction of an RAA-CRISPR detection platform for differentiation of Brucella abortus A19-∆VirB12 vaccine strain from wild-type strains.
Epidemiological characteristics of brucellosis in non-occupational population in Zhejiang Province, China, 2018-2024: epidemic trend and infection analysis.
The clinical Epidemiological Characteristics and Diagnosis/Treatment of Brucellosis infection Patients in Gansu Province: A retrospective study from 2019 to 2022.
Development and validation of a VirB12-based indirect ELISA for differentiating Brucella abortus infection from A19-ΔVirB12 vaccination.
📚 EuropePMC8.835 artigos no totalmostrando 198
Brucella abortus and public health risk: Prevalence in milk sold at open markets in Cameroon.
PLoS neglected tropical diseasesBrucellosis Complicated by Thyroid Abscess and Life-Threatening Hemophagocytic Syndrome: A Case Report.
Infection and drug resistanceHuman brucellosis in pregnancy in western Uganda: High seroprevalence and health risk factors identified in a cross-sectional study.
PLoS neglected tropical diseasesASAP1 gene InDel variants are associated with enhanced goat resistance against Brucella infection.
Animal bioscienceNatural history of latent brucellosis and diagnostic performance of B-SPOT: a 24-month prospective cohort study based on large-scale screening in northern China.
Emerging microbes & infectionsBrucellosis vaccine development: immunological mechanisms, animal models, and future directions.
Archives of microbiologyEstablishment of a rapid Brucella detection method based on MCDA-CRISPR dual signal amplification system for reducing transfusion-transmitted diseases.
Scientific reportsSocioeconomic drivers of human Brucellosis in Ningxia, China: A one health and spatiotemporal analysis for targeted intervention.
PLoS neglected tropical diseasesSocio-economic impact of bovine brucellosis and the need for effective control strategies.
Veterinary research communicationsSeroprevalence and Associated Risk Factors of Brucellosis in Backyard Dairy Cattle in the Western Buffer Zone of Chitwan National Park, Nepal.
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Diagnostic microbiology and infectious diseaseDifferentiating scrub typhus meningitis from brucellar meningitis in children: A single-center retrospective study.
PLoS neglected tropical diseasesSuccessful Conservative Management of Complicated Brucella Endocarditis.
Journal of medical casesClinical and Laboratory Profile of Patients with Tropical Coinfections Admitted at a Tertiary Care Center in North India.
The Journal of the Association of Physicians of IndiaHuman Health Risk Assessment of Informal Slaughter by Small-Scale Farmers in Gauteng Province, South Africa, Focusing on Brucella abortus.
Veterinary medicine internationalHollow viscus perforation secondary to brucellosis: a rare case report.
International journal of surgery case reportsSerological evaluation of brucellosis in nomadic small ruminants in Southeastern Türkiye.
BMC veterinary researchAnalysis of Bacteremic Brucellosis Caused by Brucella melitensis Biovar 3 vs. Non-Bacteremic Cases in an Endemic Region of Türkiye.
Infectious diseases & clinical microbiologyThe ID Screen® Brucella suis Indirect ELISA is a valuable supplement for serological diagnosis of porcine brucellosis.
Schweizer Archiv fur TierheilkundeConjunctival administration of H38ΔwbkF rough vaccine as an effective strategy to protect against Brucella ovis infection while minimizing serological interference.
Veterinary researchBovine brucellosis seropositivity in Mpumalanga Province, South Africa, 2021-2024: Temporal, and spatial trends.
PloS oneFrom tests to truth: A misclassification-aware machine learning framework for estimating brucellosis seroprevalence in wild canids.
PLoS neglected tropical diseasesSpatial characteristics and driving factors of human brucellosis and plague infections in the Meriones unguiculatus plague focus in China.
One health (Amsterdam, Netherlands)A case report of cervical spine epidural abscess caused by brucellosis.
Surgical neurology internationalFrequency and Etiologies of Peripheral Type Cranial Neuropathy in the Neurology Inpatient Clinic.
Noro psikiyatri arsiviOsteoarticular involvement in pediatric brucellosis: A 15-year retrospective study from a tertiary care pediatric hospital.
Journal of tropical pediatricsPrevalent Infectious Causes of Abortion in the Ruminant Population in Iran- A Literature Review.
Archives of Razi InstituteNeurobrucellosis: An Uncommon but Important Cause of Sensorineural Hearing Loss: a case report.
Journal of otologyBrucella Omp25 activates the unfolded protein response to promote intracellular proliferation and inflammation.
The Journal of biological chemistryMeta-analysis of brucellosis and relative risks.
MedicineGenome-wide comparison analysis of Brucella attenuated vaccine strain BA0711 and Brucella wild-type strain M28 and establishment of a duplex qPCR differentiation method.
Veterinary journal (London, England : 1997)A rare complication in humans of a rare disease in Germany: a case of bilateral tubo-ovarian abscesses caused by Brucella melitensis.
InfectionDevelopment and Validation of a Population Assay for the Seroprevalence of Lumpy Skin Disease.
MicroorganismsDiagnostic Value of Mean Platelet Volume and Hematological Inflammatory Ratios in Brucellosis: A Case-Control Study.
Life (Basel, Switzerland)Development and Evaluation of Multiple Droplet Digital PCR Method for Specific Detection and Differentiation of Brucella melitensis and Brucella abortus.
Animals : an open access journal from MDPIFirst report of the isolation, characterization, and genotyping of Brucella abortus biovar 9 in Brazil.
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]Innate Immunity Trained in the Protective Response of Vaccine Candidates Against Intracellular Pathogens.
VaccinesBrucellosis in Kazakhstan: Knowledge, Attitudes, and Practices Among Smallholder Farmers and Veterinary Specialists.
Veterinary sciencesDemyelinating Neurobrucellosis Presenting With Neuropsychiatric Manifestations.
Case reports in medicineSpatiotemporal Early Warning of Human Brucellosis in Hubei Province Using Coupled Ecological-Time Series Models.
Zoonoses and public healthCongenital brucellosis in a preterm infant: A case report from France and literature review.
IDCasesTuft-cell-derived IL-25 regulates intestinal ILC2 in response to Brucella infection.
Frontiers in immunologyMyeloid-derived suppressor cells and their subsets serve as potential biomarkers for the progression of brucellosis.
Frontiers in microbiologyBiological characteristics, human cell interaction mechanisms, and differential clinical outcomes of infection by Brucella melitensis, Brucella abortus, Brucella suis, and Brucella canis.
Archives of microbiologyA multi-source data-based modelling study on brucellosis transmission risk analysis and control strategies in Zhejiang Province, China.
BMC infectious diseasesFirst isolation and molecular confirmation of Brucella canis in dogs from Egypt.
BMC microbiologySpinal brucellosis - A mimicker of spinal tuberculosis: An analysis of 10 patients from a tertiary care center in India.
Journal of craniovertebral junction & spineNeurobrucellosis presenting with concurrent paraplegia and global aphasia in an elderly butcher: A case report and literature review.
IDCasesComprehensive analysis of molecular immunological characteristics and potential biomarkers in brucellosis.
Frontiers in immunologyBlood culture positivity and its clinical determinants among hospitalized male patients with newly diagnosed, laboratory-confirmed brucellosis: a hospital-based retrospective study.
Frontiers in microbiologyPrevalence and risk factors of neglected zoonoses in Ethiopian small ruminants: a focus on Q fever, brucellosis, chlamydiosis, and toxoplasmosis.
One health outlookEvaluation of brucellosis eradication strategies in water buffalo in a key dairy production area of southern Italy.
Frontiers in microbiology"MLVA_5: A reduced marker scheme for phylogeographic analysis of Brucella canis".
Comparative immunology, microbiology and infectious diseasesBrucellar Spondylodiscitis 20 Years Post Infection.
The American journal of tropical medicine and hygieneDevelopment of serologic diagnostic test based on in silico predicted synthetic peptides for Brucella canis in dogs.
PloS oneSensitivity of current laboratory methods for brucellosis diagnosis at endemic foci.
BMC microbiologyInfectious disease burden and surveillance challenges in Jordan and Palestine: a systematic review and meta-analysis.
Frontiers in digital healthKnowledge, attitudes, and practices among livestock owners, traders, and slaughterhouse inspectors in Cameroon reveals marginal understanding of livestock and human brucellosis.
Frontiers in veterinary scienceAssessment of Brucellosis Seropositivity in Patients Diagnosed with Tularemia.
Journal of clinical practice and researchEnhanced immunogenicity of the Brucella A19 ΔbtpB mutant leads to accelerated clearance in the host.
Frontiers in immunologyCorrigendum to "Integrated bioinformatics and machine learning deciphering IL12RB2 and FYN as key immune biomarkers in brucellosis" [Int. Immunopharmacol. 173 (2026) 116268].
International immunopharmacologyPrioritization of zoonotic diseases in Bhutan through a One Health framework.
One health outlookBrucella's Emerging Threat: A Global Systematic Review and Meta-Analysis Revealing Temporal, Geographic and Species-Specific Patterns of Antimicrobial Resistance.
Veterinary medicine internationalAn 18-year retrospective analysis of changing patterns in pediatric brucellosis in Jinan, China.
Scientific reportsDevelopment of a cELISA based on a trivalent nanobody-HRP fusion protein targeting BP26 for brucellosis diagnosis.
TalantaPredictors of Brucella spp. bacteraemia at admission among adults with brucellosis: a two-centre retrospective cohort study in Ningxia, China.
BMC infectious diseasesBrucella-infected macrophage-derived microparticles enhance the host anti-Brucella acquired immune response.
Veterinary microbiologyEvaluation of Humoral and Cellular Immune Responses to the Conjunctival Brucella abortus S19 Vaccine in Türkiye.
Vector borne and zoonotic diseases (Larchmont, N.Y.)Assessing human brucellosis infection rates in high-risk occupational groups.
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Veterinary medicine and scienceEvolution and phylogenetic characteristics of the first Brucella canis strain isolated from a human patient in Yunnan Province, China.
Frontiers in cellular and infection microbiologyThe impact of STING signaling on myeloid cells highlights macrophages as the major player in controlling Brucella abortus.
Frontiers in immunologyThe genome of Phlebotomus chinensis, the primary vector of visceral leishmaniasis in China: insights from chromosome-level assembly and comparative analysis.
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Veterinary immunology and immunopathologyBrucella brain abscess: a rare but serious neurological complication-case report and literature review.
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Journal of bacteriologyPrevalence and spatial distribution characteristics of human brucellosis in Ningxia from 2010 to 2024.
PLoS neglected tropical diseasesMolecular identification of Brucella abortus in secondary hosts of goats and sheep in Magelang, Central Java, Indonesia.
Open veterinary journalThe effect of a community intervention based on protection motivation theory on brucellosis preventive behaviors in rural residents.
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BMC medical imagingDevelopment of One Health-based community surveillance system to study zoonotic diseases: a study protocol.
Frontiers in public healthAn unusual case of neurobrucellosis with intracranial hypertension and bilateral abducens nerve palsy.
BMC infectious diseasesTANK-binding Kinase 1 regulates the intracellular survival of Brucella.
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International immunopharmacologyNeurobrucellosis in an 11-year-old child: A rare case report of brain microabscesses from an endemic region.
The Journal of international medical researchPhylogeny-guided multi-epitope vaccine design targeting conserved and divergent regions of Brucella OMP2, OMP25, and OMP31: an immunoinformatics study.
BMC immunologyBrucella, Coxiella, and Theileria Species DNA in Haemaphysalis qinghaiensis Ticks Collected from Goats and Sheep in Qinghai Province, Northwest China.
Tropical medicine and infectious diseaseBrucellosis Presenting as Cavitary Pneumonia with Multiple Pulmonary Nodules: A Rare Presentation.
Annals of African medicineCervical brucellar spondylitis: Current management strategies and future directions.
Infectious medicineSpatiotemporal dynamics of Brucella immune evasion across infection stages.
Frontiers in immunologyIdentification and Characterization of Outer Membrane Proteins and Membrane Spanning Protein Complexes in Brucella melitensis.
ProteinsDihydroartemisinin-Loaded ZIF-8 Nanoparticles for Antibacterial and Osteogenic Dual Therapy in Brucella-Infected Bone Defects.
ACS applied materials & interfacesTwo Years, Many Clues: Diagnostic Journey and Treatment of Chronic Neurobrucellosis in an Elderly Woman.
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Antimicrobial agents and chemotherapyNeurobrucellosis presenting as acute stroke with brain abscesses: a case report.
American journal of neurodegenerative diseaseBvrR From Brucella abortus Induces Neuroinflammation Through IRE1-Mediated Activation of ATF2 and NF-κB.
MicrobiologyOpenGenomic analysis of Brucella Ovis in Italy reveals high genetic diversity and a novel lineage.
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BMC infectious diseasesBrucella melitensis sacroiliitis as an unusual culprit for fever of unknown origin (FUO).
BMJ case reportsAll spinal infections are not always tuberculosis: A rare case of brucella spondylodiscitis in South India.
Diagnostic microbiology and infectious disease[Pathogenetic and therapeutic approaches to the correction of neurocognitive disorders in patients with chronic brucellosis].
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Research in veterinary scienceComparison of serological tools for reliable diagnosis of brucellosis circulation in the West-African context.
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Journal of medical case reportsPediatric brucellosis with negative serology: Molecular confirmation and implications for epidemiological surveillance in Mexico.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious DiseasesIntraoperative Transmission of Brucellae.
Emerging infectious diseasesBrucella abortus infection exploits ZDHHC3-mediated STAT3 palmitoylation to regulate host responses and promote persistence.
Veterinary researchStrengthening brucellosis prevention and control in Iran: policy priorities informed by stakeholder networks, agenda-setting dynamics, and economic burden evidence.
Tropical medicine and healthStructural Analysis and Inhibitor Modeling of Bacterioferritin From Brucella abortus.
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The Pediatric infectious disease journalUnilateral septic sacroiliitis caused by Brucella Melitensis in the postpartum period: A rare case report.
IDCasesDisruption of purine de novo synthesis pathway impairs membrane homeostasis, intracellular survival, and virulence of Brucella melitensis.
Frontiers in microbiologyDevelopment of Visual and Fluorescence Detection Method of Brucella by RPA-CRISPR/Cas12a Assay.
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyScoping review of brucellosis in Armenia: persistent neglect, significant knowledge gaps, and a necessity for innovative research, surveillance, and control.
Frontiers in veterinary scienceAssessment and Management of the Impact of Bovine Brucellosis on Dairy Herd Performance and Profitability.
Veterinary sciencesUnveiling Equine Abortion Pathogens: A One Health Perspective on Prevalence and Resistance in Northwest China.
Pathogens (Basel, Switzerland)Impact of the "Class B infectious disease Class B management" policy on the number of cases and deaths of notifiable infectious diseases in China during the COVID-19 epidemic: a nationwide interrupted time series study.
BMC public healthComparative genomics of Brucella species reveals key determinants of secondary metabolism, antimicrobial resistance, and virulence.
Scientific reportsDesign of a Prospective Human-Animal Cohort Study to Evaluate the Role of Camels and Other Livestock Species in the Transmission of Brucella spp. to Humans in Kenya.
International journal of environmental research and public healthBrucella melitensis clinical isolate modulates osteoclast differentiation to drive pathological bone destruction in brucellar arthritis.
Frontiers in cellular and infection microbiologyTyphoidal tularemia with pancytopenia and pericarditis in a georgian adolescent.
IDCasesEvaluation of a competitive ELISA for detecting the anti-Brucella antibodies in serum and milk of goats and cattle.
Veterinary research communicationsSuccessful endovascular and open repair for brucellosis-associated multiple pseudoaneurysms.
European heart journalOMP16-targeting monoclonal antibodies H4 and E6 reveal essential linear epitopes for Brucella immunoprotection.
International journal of biological macromoleculesComplete genome assembly and functional characterization of Brucella melitensis strain IMHB1 from a clinical isolate in Inner Mongolia, China.
Frontiers in cellular and infection microbiologyComprehensive comparative analysis of explainable deep learning model for differentiation of brucellar spondylitis and tuberculous spondylitis through MRI sequences.
European journal of medical research[Epidemiological characteristics and spatial clustering of human brucellosis in Hunan Province, 2016-2024].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhiImmunogenicity of a Lipopolysaccharide Brucella melitensis Vaccine in Goats: An Exploratory Study.
VaccinesIntegrated Surveillance for Human and Animal Brucellosis in Kenya: A Predictive Analysis.
Tropical medicine and infectious diseaseBacillary Layer Detachment Associated with Ocular Brucellosis.
Ophthalmology. RetinaA Rare Case of Splenic Infarction Due to Brucellosis.
The new microbiologicaBrucellosis uveitis: A case report and literature review.
MedicineA novel diagnostic model for brucellosis spondylitis using serum PINP and inflammatory factors: a dual-cohort study from Northwest China.
BMC infectious diseasesMechanism of Brucella pathogenesis mediated by outer membrane protein Omp19: Synergistic activation of cytokine storm and dual apoptotic pathways.
Microbial pathogenesisTransforming One Health in India: National Multisectoral Mixed Method Study on Prioritization of Zoonotic Diseases.
JMIR public health and surveillanceCase Report: Peritoneal dialysis-associated peritonitis caused by Brucella.
Frontiers in medicineDevelopment and evaluation of novel Brucella diagnostic antigen protein ST.
BMC infectious diseasesSeroprevalence of brucellosis in humans and livestock in Sub-Saharan Africa: a systematic review and meta-analysis.
Systematic reviewsFirst confirmation of Mycobacterium tuberculosis complex from medieval Ireland by aDNA analysis - palaeopathological and microbial findings.
Tuberculosis (Edinburgh, Scotland)[Evaluation of Gradient-Variant Quantum Dot Fluorescence Technology for Rapid Detection of Brucella].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science editionFirst documented case of equine brucellosis in Libya: a case report.
Journal of equine scienceSpatial and Temporal Distribution of Febrile Illnesses in Uganda: Case Studies of Brucellosis, Malaria and Typhoid Fever (2016-2023).
Journal of tropical medicineClinical and mechanistic insights into Brucella and viral co-infection.
Current opinion in virologyClinical Differences Between Culture-positive and Culture-negative Brucellosis in Childhood: A Single-center Experience.
The Pediatric infectious disease journalBrucellosis complicated by aortitis and thyroiditis: a case report.
BMC infectious diseasesA new member of the novel, non-core Brucella clade: An exotic frog isolate closely related to atypical Brucella isolates from recent human brucellosis cases in Australia.
BMC microbiologyClinical Features and Treatment Differences Among Tuberculous, Brucellosis, and Pyogenic Spondylitis: A Cohort Study.
Infection and drug resistanceEpidemiological baseline of Brucella spp. in South African wildlife.
PLoS neglected tropical diseasesThe European Union One Health 2024 Zoonoses Report.
EFSA journal. European Food Safety AuthorityPreliminary Retrospective Analysis of X-Ray, CT, and MRI Imaging Features of Brucellar Spondylodiscitis Diagnosis.
Journal of inflammation researchEcological study of human brucellosis in Iran from 2000 to 2023 and the limited role of climatic factors.
Scientific reportsThe Brucella type IV secretion system and effector proteins.
microLifeGiant intracranial Brucella abscess after head trauma: a Case Report of neurobrucellosis in an urban elderly male without exposure history.
Frontiers in medicineA case report of hemophagocytic syndrome induced by Brucella melitensis biovar 3.
Frontiers in immunologyEpidemiological analysis of infectious diseases in older people in China from 2014 to 2022: a population-based study.
The Lancet regional health. Western PacificFirst documented case of cutaneous anthrax and brucellosis coinfection in a human in rural northern China: a case report.
BMC infectious diseasesThe synergistic pathogenic mechanism of Brucella melitensis M5-90 effector protein BspC in regulating host cell apoptosis, inflammation and oxidative stress.
Journal of medical microbiologyMachine learning-based prediction model for chronic brucellosis: a multi-feature approach using clinical and laboratory data.
Frontiers in cellular and infection microbiologyAntimicrobial and therapeutic effect of gold Nanoparticle-Aptamer conjugated antimicrobial peptide RW-BP100 in Brucella canis infected mice and RAW 264.7 cells.
Microbial pathogenesisMultiepitope fusion protein-based ELISA for enhanced brucellosis serodiagnosis.
PLoS neglected tropical diseasesBiosecurity practices on small-ruminant farms in five Turkish provinces: a cross-sectional survey with multiple correspondence analysis.
Frontiers in veterinary scienceGlobal research hotspots and trends in brucellosis: a bibliometric and visualization analysis based on CiteSpace and VOSviewer.
Frontiers in medicineMusculoskeletal brucellosis presenting as low back pain and a limp.
QJM : monthly journal of the Association of PhysiciansCamel brucellosis: a narrative review of epidemiology and control strategies.
Veterinary research communicationsCase Report: Next-generation metagenomic sequencing in the diagnosis of Brucella-associated joint infections-a case series analysis and comprehensive literature review.
Frontiers in medicineSingle-cell transcriptomics reveals dynamic reprogramming of testicular immunity in Brucella-infected goat testis.
Zoological researchGeographic distribution and genetic diversity of Brucella melitensis from Yunnan province, China.
BMC microbiologyKnowledge, attitude, and practice regarding brucellosis among confirmed cases.
Scientific reportsExploring community-based reporting of livestock abortions for rift valley fever and brucellosis surveillance in Uganda: a pilot study.
Scientific reportsProtocol for a randomized controlled trial on the impact of a health action process approach model-based mobile health intervention via WeChat on health behaviors of brucellosis patients.
Frontiers in public healthThe economic burden of brucellosis in Western Iran.
Tropical medicine and healthBrucellosis prevention and control in small ruminants using a test and slaughter strategy in the pastoral Afar Region of Ethiopia: A pilot study.
Preventive veterinary medicineUntargeted metabolomics pilot study using UHPLC-Q-Orbitrap to investigate potential metabolic markers of Brucella abortus biovars.
Analytical methods : advancing methods and applicationsAssociações
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Brucella abortus and public health risk: Prevalence in milk sold at open markets in Cameroon.
- Human brucellosis in pregnancy in western Uganda: High seroprevalence and health risk factors identified in a cross-sectional study.
- ASAP1 gene InDel variants are associated with enhanced goat resistance against Brucella infection.
- Socioeconomic drivers of human Brucellosis in Ningxia, China: A one health and spatiotemporal analysis for targeted intervention.
- Seroprevalence and Associated Risk Factors of Brucellosis in Backyard Dairy Cattle in the Western Buffer Zone of Chitwan National Park, Nepal.
- One health perspectives on the epidemiological features and changing incidence of natural focus and vector-borne infectious diseases in China: An observational trend study.
- Construction of an RAA-CRISPR detection platform for differentiation of Brucella abortus A19-∆VirB12 vaccine strain from wild-type strains.
- Epidemiological characteristics of brucellosis in non-occupational population in Zhejiang Province, China, 2018-2024: epidemic trend and infection analysis.
- The clinical Epidemiological Characteristics and Diagnosis/Treatment of Brucellosis infection Patients in Gansu Province: A retrospective study from 2019 to 2022.
- Development and validation of a VirB12-based indirect ELISA for differentiating Brucella abortus infection from A19-ΔVirB12 vaccination.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:1304(Orphanet)
- MONDO:0005683(MONDO)
- GARD:5966(GARD (NIH))
- Busca completa no PubMed(PubMed)
- Artigo Wikipedia(Wikipedia)
- Q156050(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
