Perturbação de hiperatividade com défice de atenção (PHDA) (português europeu) ou Transtorno do Déficit de Atenção / Hiperatividade (TDAH) (português brasileiro) é um transtorno neurobiológico ligado ao neurodesenvolvimento caracterizado pela desatenção, hiperatividade, desregulação emocional e a impulsividade em graus inconsistentes com o nível de desenvolvimento do indivíduo. Os critérios de diagnóstico requerem que os sintomas se comecem a manifestar antes dos doze anos de idade, que estejam presentes durante mais de seis meses e que causem problemas em pelo menos dois cenários diferentes, como na escola e em casa, por exemplo. Em crianças, a desatenção é muitas vezes a causa de maus resultados escolares.
Introdução
O que você precisa saber de cara
Epilepsia rara caracterizada por convulsões desencadeadas por pensamentos específicos, imagens mentais ou raciocínio complexo. A herança é desconhecida.
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
1/2k
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Entender a doença
Do básico ao detalhe, leia no seu ritmo
Preparando trilha educativa...
Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Linha do tempo da pesquisa
Triagem neonatal (Teste do Pezinho)
A triagem neonatal permite diagnóstico precoce e início imediato do tratamento.
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Genética e causas
O que está alterado no DNA e como passa nas famílias
Nenhum gene associado encontrado
Os dados genéticos desta condição ainda estão sendo catalogados.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Convulsões induzidas pelo pensamento
Selecione um estado ou use sua localização para ver resultados.
Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.
Pesquisa ativa
Ensaios clínicos abertos e novidades científicas recentes
Ensaios em destaque
Pesquisa e ensaios clínicos
0 ensaios clínicos encontrados.
Publicações mais relevantes
International Consensus on the Evaluation and Management of Hypothalamic Hamartomas: Results From a Modified Delphi Survey.
Este consenso internacional sobre hamartomas hipotalâmicos (HH) sublinha a importância das convulsões gelásticas e dacrísticas para o diagnóstico, que deve ser confirmado por uma ressonância magnética cerebral de 3T com protocolo para epilepsia. A avaliação cirúrgica deve ser considerada precocemente, logo após a falha do primeiro medicamento antiepiléptico, com a cirurgia sendo recomendada após o insucesso de dois fármacos, utilizando técnicas diversas como a ablação. O manejo dos HH exige uma abordagem multidisciplinar, incluindo avaliações neuropsicológicas e endocrinológicas pré e pós-operatórias para otimizar os resultados e o bem-estar geral do paciente.
🇧🇷 traduzido[Expert consensus on the diagnosis and treatment of pediatric febrile infection-related epilepsy syndrome (2026)].
A Síndrome de Epilepsia Relacionada à Infecção Febril (FIRES) é uma condição pediátrica grave e rara, caracterizada por crises epilépticas de difícil controle (super-refratárias) que surgem rapidamente após uma infecção febril, evoluindo frequentemente para epilepsia refratária e comprometimento cognitivo. Devido à falta de reconhecimento entre pediatras e à ausência de diretrizes padronizadas, um consenso de especialistas foi desenvolvido com 17 recomendações, visando normatizar o diagnóstico e tratamento clínico desta síndrome. Este consenso é crucial para melhorar a gestão da FIRES, beneficiando pacientes e fornecendo orientação clara aos médicos.
🇧🇷 traduzidoTo see or not to see the vet: A vignette-based study of decision-making by UK dog owners regarding seeking veterinary care for commonly presenting conditions.
Este estudo revelou que, embora tutores de cães no Reino Unido sejam precisos em identificar condições com sinais clínicos externos, eles frequentemente subestimam a urgência de procurar atendimento veterinário (em quase 30% dos casos), especialmente para doenças menos visíveis. Para pacientes (tutores), é crucial estar ciente dessa tendência à subestimação da urgência. Para médicos (veterinários), o estudo sugere que o aprimoramento da acessibilidade a serviços de triagem, telemedicina e o fornecimento de "prescrições de informação" claras podem otimizar o fluxo de trabalho e melhorar o bem-estar canino, apoiando decisões mais adequadas dos tutores.
🇧🇷 traduzidoDefining chronic ambulatory care sensitive conditions in Malaysia: a collaborative consensus study.
Este estudo identificou na Malásia dez condições crônicas, incluindo **convulsões e epilepsia**, onde um acompanhamento ambulatorial eficaz pode prevenir internações hospitalares. Para pacientes, isso significa que uma boa gestão da sua condição fora do hospital é fundamental para evitar complicações que levem à hospitalização. Para médicos, o estudo ressalta que cerca de 8,6% das internações analisadas poderiam ter sido evitadas com a otimização dos cuidados ambulatoriais, destacando a importância de focar na prevenção e no suporte contínuo a estas condições para reduzir o risco de hospitalização.
🇧🇷 traduzidoGlobal, regional, and national burden of chronic respiratory diseases and impact of the COVID-19 pandemic, 1990-2023: a Global Burden of Disease study.
Este estudo global revela que as doenças respiratórias crónicas (como DPOC e asma) causaram 569 milhões de casos e 4,2 milhões de mortes em 2023, apesar de uma diminuição de 25,7% na taxa de mortalidade geral desde 1990. No entanto, doenças como a pulmonar intersticial e sarcoidose aumentaram, especialmente em idosos, com o tabagismo, IMC elevado e exposição à sílica sendo fatores de risco chave. Durante a pandemia de COVID-19, houve um modesto aumento na incidência, mas uma aceleração na queda das taxas de mortalidade, sublinhando a necessidade contínua de atenção médica e prevenção.
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International Consensus on the Evaluation and Management of Hypothalamic Hamartomas: Results From a Modified Delphi Survey.
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The American journal of tropical medicine and hygieneThe concept of "control" in people with epilepsy: A qualitative study.
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Autism : the international journal of research and practiceThe Unconventional Effects of the Ketogenic Diet (KD) in Preclinical Epilepsy.
Epilepsy currentsIdentification of Potential Clusters of Signs and Symptoms to Prioritize Patients' Eligibility for AADCd Screening by 3-OMD Testing: An Italian Delphi Consensus.
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BMC psychiatryFour questions to assess attitudes toward epilepsy, the caveness questions: Analytical study to verify the usefulness of the Japanese version.
HeliyonDirect stimulation of anterior insula and ventromedial prefrontal cortex disrupts economic choices.
Nature communicationsDeveloping feasible person-centred care alternatives to emergency department responses for adults with epilepsy: a discrete choice analysis mixed-methods study.
Health and social care delivery researchTherapeutic approaches targeting seizure networks.
Frontiers in network physiologyExamining change in the mental health of young people with epilepsy following a successful psychological intervention.
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The Lancet. NeurologyThe computational and neural substrates of individual differences in impulsivity under loss framework.
Human brain mappingA shared model-based linguistic space for transmitting our thoughts from brain to brain in natural conversations.
NeuronPatient organization perspective: a research roadmap for Okur-Chung Neurodevelopmental Syndrome.
Therapeutic advances in rare disease"What are your seizures telling you?": A therapeutic tool for functional seizures.
Epilepsy & behavior : E&BEffect of exercise on cluneal nerve entrapment neuropathy: a case report.
Journal of medical case reportsThinking of epilepsy as a symptom.
The Lancet. NeurologyBeta activity in human anterior cingulate cortex mediates reward biases.
Nature communicationsDecision making for health-related research outcomes that alter diagnosis: A model from paediatric brain tumours.
Neuropathology and applied neurobiologyEscaping the Procrustean Bed: A Perspective on Pediatric Stereoelectroencephalography.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic SocietyChronic Treatment with Oxcarbazepine Attenuates Its Anticonvulsant Effect in the Maximal Electroshock Model in Mice.
International journal of molecular sciencesA comparison of patients with epileptic seizures (ES) versus those with psychogenic non-epileptic seizures (PNES) on measures of alexithymia, mood, and anxiety.
Seizure"Your Thoughts are (were) Free!": Brain-Computer-Interfaces, Neurofeedback, Detection of Deception, and the Future of Mind-Reading.
Applied psychophysiology and biofeedbackA transdiagnostic approach to neurodiversity in a representative population sample: The N+ 4 model.
JCPP advancesAssociation of Prenatal Exposure to Antiseizure Medications With Creative and Executive Function at Age 4.5 Years.
NeurologyConsensus Guideline on the Management of Epilepsy in Egypt: A National Delphi Consensus Study.
Epilepsia openHippocampal sharp-wave ripples correlate with periods of naturally occurring self-generated thoughts in humans.
Nature communicationsSequential graph convolutional network and DeepRNN based hybrid framework for epileptic seizure detection from EEG signal.
Digital healthPublic Awareness of Epilepsy and Social Attitude Toward Persons With Epilepsy Among the General Population in Makkah, Saudi Arabia.
CureusThe role of the human hippocampus in decision-making under uncertainty.
Nature human behaviourCurrent challenges in focal epilepsy treatment: An Italian Delphi consensus.
Epilepsy & behavior : E&B[Interpretation of treatment of seizures in the neonate: guidelines and consensus-based recommendations-special report from the ILAE Task Force on Neonatal Seizures(2023)].
Zhonghua er ke za zhi = Chinese journal of pediatricsDeveloping an alternative care pathway for emergency ambulance responses for adults with epilepsy: A Discrete Choice Experiment to understand which configuration service users prefer. Part of the COLLABORATE project.
SeizureGaining consensus on emotional wellbeing themes and preferences for digital intervention type and content to support the mental health of young people with long-term health conditions: A Delphi study.
Health expectations : an international journal of public participation in health care and health policyBerberine and hesperidin prevent the memory consolidation impairment induced by pentylenetetrazole in zebrafish.
Behavioural brain researchBrivaracetam use in clinical practice: a Delphi consensus on its role as first add-on therapy in focal epilepsy and beyond.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical NeurophysiologyA Communication and Decision-Making Framework for Pediatric Precision Medicine.
PediatricsGlobal, regional, and national burden of disorders affecting the nervous system, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
The Lancet. NeurologyConsensus guidelines for the diagnosis and management of succinic semialdehyde dehydrogenase deficiency.
Molecular genetics and metabolismProceedings of the 11th Annual Deep Brain Stimulation Think Tank: pushing the forefront of neuromodulation with functional network mapping, biomarkers for adaptive DBS, bioethical dilemmas, AI-guided neuromodulation, and translational advancements.
Frontiers in human neuroscienceAdvances in epileptic network findings of hypothalamic hamartomas.
Journal of central nervous system diseaseTechnical Tips: The Role of the Charge Neurodiagnostic Technologist.
The Neurodiagnostic journalGrading system for assessing the confidence in the epileptogenic zone reported in published studies: A Delphi consensus study.
EpilepsiaIntracranial electroencephalography reveals effector-independent evidence accumulation dynamics in multiple human brain regions.
Nature human behaviourThe science of uncertainty guides fetal-neonatal neurology principles and practice: diagnostic-prognostic opportunities and challenges.
Frontiers in neurologyCognitive and psychological dysfunction is present after a first seizure, prior to epilepsy diagnosis and treatment at a First Seizure Clinic.
Epilepsia openIntracranial Recordings of the Human Orbitofrontal Cortical Activity during Self-Referential Episodic and Valenced Self-Judgments.
The Journal of neuroscience : the official journal of the Society for NeuroscienceKetogenic Diet: Parental Experiences and Expectations.
Journal of child neurologyGuidelines for Specialized Epilepsy Centers: Executive Summary of the Report of the National Association of Epilepsy Centers Guideline Panel.
NeurologyPhase synchronization during the processing of taxonomic and thematic relations.
Brain and languageCirculating microRNAs from plasma as preclinical biomarkers of epileptogenesis and epilepsy.
Scientific reportsExperience sampling methodology study of anxiety and depression in adolescents with epilepsy: The role of metacognitive beliefs and perseverative thinking.
Epilepsy & behavior : E&BEvaluation and systematic review of guidance documents for status epilepticus.
Epilepsy & behavior : E&BEvaluation of Cognitive Impairment in Refractory Temporal Lobe Epilepsy Patients Concerning Structural Brain Lesions.
Basic and clinical neuroscienceThe brain dynamics of visuospatial perspective-taking captured by intracranial EEG.
NeuroImageVariation in seizure risk increases from antiseizure medication withdrawal among patients with well-controlled epilepsy: A pooled analysis.
Epilepsia openMental health interventions for children and young people with long-term health conditions in Children and Young People's Mental Health Services in England.
Clinical child psychology and psychiatryUsing design thinking to strengthen the community pharmacist's role in epilepsy care.
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Nature communicationsCan knowledgeable experts assess costs and outcomes as if they were ignorant? An experiment within precision medicine evaluation.
International journal of technology assessment in health careEpilepsy Surgery: A Story of Diminishing Returns Over Time? Think Differently and Think Again.
Epilepsy currentsEstimating Patient-Level Uncertainty in Seizure Detection Using Group-Specific Out-of-Distribution Detection Technique.
Sensors (Basel, Switzerland)Interstitial laser ablation for epilepsy: beauty lies in the eye of the beholder.
Journal of neurology, neurosurgery, and psychiatryTheta Oscillations Support Prefrontal-hippocampal Interactions in Sequential Working Memory.
Neuroscience bulletinAssessment of knowledge, attitude and practice (KAP) of parents/caregivers towards epilepsy in children - A cross- sectional observational study.
HeliyonReadability and content gaps in online epilepsy surgery materials as potential health literacy and shared-decision-making barriers.
Epilepsia openImplementation of a 7T Epilepsy Task Force consensus imaging protocol for routine presurgical epilepsy work-up: effect on diagnostic yield and lesion delineation.
Journal of neurologyDefault mode network spatio-temporal electrophysiological signature and causal role in creativity.
bioRxiv : the preprint server for biologyExamination of the level of tolerance of uncertainty and psychological wellness of patients with epilepsy.
Epilepsy & behavior : E&BTreatment of seizures in the neonate: Guidelines and consensus-based recommendations-Special report from the ILAE Task Force on Neonatal Seizures.
EpilepsiaPeri-ictal heart rate changes in patients with epilepsy.
Nigerian journal of clinical practiceA unique association? A narcolepsy type 1 case comorbid with Primary Biliary Cholangitis.
Sleep medicineImpaired cardiac modulation in patients with functional seizures: Results from a face intensity judgment task.
EpilepsiaPractice Standards for the Use of Multimodality Neuromonitoring: A Delphi Consensus Process.
Critical care medicineTreatment of Seizures in the Neonate: Special Report From the ILAE Task Force on Neonatal Seizures, 2022.
Indian pediatricsTiming of Allocentric and Egocentric Spatial Processing in Human Intracranial EEG.
Brain topographyPrecision or narrative medicine? Child neurology needs both!
Archives de pediatrie : organe officiel de la Societe francaise de pediatrieMapping Lesion-Related Epilepsy to a Human Brain Network.
JAMA neurologyAssessment of epilepsy awareness, knowledge, and attitudes among preclinical and clinical medical students in the West Bank of Palestine.
Epilepsy & behavior : E&BEpileptic detection in single and multi-lead EEG signals using persistent homology based on bi-directional weighted visibility graphs.
Chaos (Woodbury, N.Y.)Nationwide Study of Postlegalization Marijuana Use Among Patients With Epilepsy in Canada.
Neurology. Clinical practiceCan the Gut Microbiota Serve as a Guide to the Diagnosis and Treatment of Childhood Epilepsy?
Pediatric neurologyImpact of metacognition on attitudes toward epilepsy in medical students.
Epilepsy & behavior : E&BValproic Acid-Associated Hyperammonemia: A Systematic Review.
Journal of clinical psychopharmacologyApplying systems thinking to unravel the mechanisms underlying orthostatic hypotension related fall risk.
GeroScience[Analysis of clinical features and PAK1 gene variant in a child with epilepsy and global developmental delay].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics[Use of isoflurane as treatment for super-refractory status epilepticus].
Revista de neurologiaDecision-making under ambiguity after frontal lobe resection for epilepsy.
Epilepsy & behavior : E&BPregnancy and Stress: Thinking Beyond Seizure Control in Women With Epilepsy.
NeurologyAnterior temporal lobectomy improved mood status and quality of life in Chinese patients with mesial temporal lobe epilepsy: a single-arm cohort study.
Chinese medical journalThe role of ATP1A3 gene in epilepsy: We need to know more.
Frontiers in cellular neuroscienceRe-Thinking Subjective Wellbeing of Latin-American and Caribbean Men With Epilepsy: Beyond Sexual Dysfunctions Issues.
International journal of public healthLong-Lasting COVID-Associated Brain Fog: A Follow-Up Study.
European neurologyProceedings of the 10th annual deep brain stimulation think tank: Advances in cutting edge technologies, artificial intelligence, neuromodulation, neuroethics, interventional psychiatry, and women in neuromodulation.
Frontiers in human neuroscienceUpdated clinical practice recommendations for managing adults with 22q11.2 deletion syndrome.
Genetics in medicine : official journal of the American College of Medical GeneticsParent perceptions and decision making about treatments for epilepsy: a qualitative evidence synthesis.
BMJ openAssociações
Organizações que acompanham esta doença — pra ter apoio e orientação
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Comunidades
Grupos ativos de quem convive com esta doença aqui no Raras
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- International Consensus on the Evaluation and Management of Hypothalamic Hamartomas: Results From a Modified Delphi Survey.
- [Expert consensus on the diagnosis and treatment of pediatric febrile infection-related epilepsy syndrome (2026)].
- To see or not to see the vet: A vignette-based study of decision-making by UK dog owners regarding seeking veterinary care for commonly presenting conditions.
- Defining chronic ambulatory care sensitive conditions in Malaysia: a collaborative consensus study.
- Global, regional, and national burden of chronic respiratory diseases and impact of the COVID-19 pandemic, 1990-2023: a Global Burden of Disease study.
- Structured debriefing and reflective thinking in speech-language pathology education: A proof-of-concept study.
- National Policies for Improving Micronutrient Intake in School Meals: A Global Cross-Sectional Study.
- Factors Associated with Critical Thinking Disposition in Postgraduate Medical Students: A Cross-sectional Study.
- Integration of patient safety into educational curricula and continuing professional training - comparison of patient safety competency models.
- 3D functional balancing in hip arthroplasty: Why the future of total hip arthroplasty must move beyond 2D thinking.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:166424(Orphanet)
- MONDO:0015647(MONDO)
- Epilepsia(PCDT · Ministério da Saúde)
- GARD:20080(GARD (NIH))
- Busca completa no PubMed(PubMed)
- Q55785622(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
