Raras
Buscar doenças, sintomas, genes...
Aplasia e agenesia cervical uterina
ORPHA:180145CID-10 · Q51.5CID-11 · LB43.1DOENÇA RARA

Hipófise é uma glândula endócrina com cerca de 1 cm de diâmetro alojada na sela túrcica ou fossa hipofisária do osso esfenoide na base do cérebro. Está localizada abaixo do hipotálamo e posteriormente ao quiasma óptico, sendo ligada ao hipotálamo pela haste pedúnculo hipofisário ou infundíbulo, é envolvida pela dura-máter. A hipófise é considerada uma "glândula mestra", pois secreta hormônios que controlam o funcionamento de outras glândulas, sendo grande parte de suas funções reguladas pelo hipotálamo.

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Introdução

O que você precisa saber de cara

📋

Condição congênita rara caracterizada pela ausência total (agenesia) ou parcial (aplasia) do colo do útero. Pode estar associada a anomalias do útero e vagina, impactando a fertilidade e a função sexual.

🏥
SUS: Cobertura mínimaScore: 15%
CID-10: Q51.5
🇧🇷Dados SUS / DATASUS
PROCEDIMENTOS SIGTAP (5)
0202010503
Cariótipo — bandas G, Q ou Rgenetic_test
0202010600
Pesquisa de microdeleções/microduplicações por FISHlab_test
0202010694
Sequenciamento completo do exoma (WES)rehabilitation
0202010260
Dosagem de alfa-fetoproteína
0301070040
Atendimento em reabilitação — doenças raras
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Sinais e sintomas

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Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa2
Últimos 10 anos200publicações
Pico2025118 papers
Linha do tempo
2024Hoje · 2026🧪 2019Primeiro ensaio clínico📈 2025Ano de pico
Publicações por ano (últimos 10 anos)

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Genética e causas

O que está alterado no DNA e como passa nas famílias

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·Pré-clínico1
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 1 ensaio
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🇧🇷 Atendimento SUS — Aplasia e agenesia cervical uterina

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Publicações mais relevantes

Timeline de publicações
0 papers (10 anos)
#1

Non-invasive host transcriptome and HPV oncogene expression map the molecular landscape of HPV-driven cervical lesions.

PloS one2026

Cervical cancer remains a significant global health burden. Current screening methods are not yet capable of detecting molecular alterations preceding cytological abnormalities. In this study, we performed integrative transcriptomic profiling of 132 HPV-positive cervical Pap Smear specimens (NILM, ASCUS, LSIL, HSIL), combining HPV genotyping, and E6/E7 mRNA quantification to map molecular progression. Our analysis revealed stage-specific signatures: NILM displayed a "stealth infection" profile marked by upregulated protein synthesis and growth signaling (EGFR/ERBB2) alongside immune suppression. ASCUS presented a critical tipping point with introduction of early oncogenic drivers (CCND1, SHH), while LSIL prioritized viral productivity with suppressed antimicrobial defenses (MPO, DEFA1). HSIL was distinct from earlier stages and defined by cell cycle hyperactivation (CDK1, PLK1), replication licensing (MCMs), and epithelial dedifferentiation. Pathway crosstalk analysis demonstrated minimal overlap between HSIL and earlier stages (OC < 0.07), highlighting molecular discontinuity during malignant transformation. Additionally, E6/E7 mRNA Ct levels were significantly associated with lesion severity (X2 = 24.407, df = 9, p = 0.003), indicating higher viral mRNA expression are associated with more severe cytological abnormalities. These findings highlight the transformative potential of transcriptomic profiling in cervical cancer prevention, offering stage-specific biomarkers to refine risk stratification. By integrating transcriptomics profiling with current clinical testing, clinicians can distinguish transient infections from high-risks lesions likely to progress. This combined approach addresses the critical limitations of morphology and DNA-based methods, enabling more precise therapeutic interventions and reducing unnecessary overtreatment, and the risk of undertreatment or dismissal of high-risk cases.

#2

Discovering the abnormalities and functional importance of ferroptosis-related molecules in cervical cancer.

International journal of medical sciences2026

Ferroptosis is an iron-dependent nonapoptotic form of cell death that links iron, lipid, and glutathione levels to a variety of disease-related activities. However, the characteristics of ferroptosis in cervical carcinoma (CC) are poorly understood. We acquired raw data on CC cohorts from The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GEO) database. Key genes were identified using differential gene expression analysis and intersected for further immune infiltration, transcription regulation, gene set variation analysis (GSVA), gene set enrichment analysis (GSEA), and drug sensitivity analysis. We also used immunohistochemical (IHC) staining to confirm the expression of important genes in cervical cancer tissue and their prognostic relevance. Finally, gene silencing and cell coculture experiments were used to verify the biological functional mechanism and its role in the tumor microenvironment (TME). Through bioinformatics analysis, we discovered that GCH1 and H1.2 are key ferroptosis-related molecules in cervical cancer. GCH1 and H1.2 could act as useful prognostic markers in cervical cancer, and in addition to their connection with the tumor microenvironment, the possible transcriptional regulatory network, hallmark pathways and chemotherapy sensitivity were also clarified. IHC of the tissue microarray (TMA) and immunofluorescence spatial distance evaluation revealed that GCH1 was more highly expressed in cervical cancer tissue than in paracarcinoma tissue. For patients with cervical cancer, higher GCH1 expression corresponded to a lower M2 cell proportion and a higher M1/M2 ratio as well as a greater GCH1-M2 distance. Silencing GCH1 in SiHa cells blocked the cell cycle, promoted apoptosis, and inhibited the migration and invasion abilities of the cells, possibly through the inhibition of the phosphorylated PI3K/AKT/mTOR pathway. Coculture of the cells with macrophages revealed that the silencing of GCH1 led to decreased expression of tumor necrosis factor (TNF), a biomarker of M1 macrophages. In this study, we performed a thorough investigation of ferroptosis-related genes and identified the functional complexity of GCH1 during tumorigenesis in cervical cancer.

#3

Infertility in an American Quarter Horse mare with cervical duplication.

Journal of equine veterinary science2026 Mar

Cervical duplication is a disorder of sexual development (DSD) that may be present in the absence of chromosomal aberrations. It is a rare cause of infertility in mares and is attributed to the failure of the Müllerian ducts to fuse properly, leading to the persistence of the median walls along the whole length of the cervix. This case report involves a 13-year-old American Quarter Horse mare with cervical duplication. Prior to this diagnostic, the mare was bred multiple times, but pregnancy was not achieved. The mare presented for a breeding soundness evaluation. During the examination an aberrant cervical conformation was palpated and further investigated. Cytogenetic analysis and a PCR for the Y-linked SRY gene and the X-linked androgen receptor gene was performed. A normal 64,XX, SRY-negative karyotype was determined. Infertility was associated with cervical abnormality, affecting in some degree uterine clearance causing accumulation of fluid seen on ultrasound.

#4

Cytological versus histological results in ASCUS cervical dysplasia - a retrospective study.

Ceska gynekologie2026

The cytological category of atypical squamous cells of undetermined significance describes cellular abnormalities that are more severe than inflammatory changes, but are quantitatively or qualitatively insufficient to be included in the squamous intraepithelial lesion category. This study aims to determine the risk level for the presence of high-grade dysplasia in patients with this cytological abnormality. We retrospectively searched our database for women with cytologically proven atypical squamous cells of undetermined significance lesions between January 2020 and June 2024. A total of 104 patients who had undergone colposcopy-directed biopsies were included in the study. Among the 104 women with confirmed atypical squamous cells of undetermined significance cytological lesions who had undergone biopsies, 56 cases (53.8%) were negative, while 48 cases (46.2%) demonstrated cervical intraepithelial neoplasia. Cervical intraepithelial neoplasia 2+ was present in 23.1% (N = 24) of the cases. Furthermore, among 77 human papillomavirus positive women, the precancerous condition was not histologically confirmed in almost half of the cases (N = 36), while in 16 of the 23 human papillomavirus negative biopsies, the precancerous condition was not confirmed. Human papillomavirus status was unknown in 4 cases. We identified a 23.1% presence of cervical intraepithelial neoplasia 2+ lesions in patients with atypical squamous cells of undetermined significance cytological findings. Our study also suggests a lower specificity, but a better negative predictive value of the human papillomavirus test in detecting cervical intraepithelial neoplasia in these patients.

#5

High-risk HPV and bacterial STIs in a primary screening population in rural Hainan, China: prevalence, co-infection, and association with cervical abnormalities.

Frontiers in public health2026

With the expansion of cervical cancer screening in China, clarifying the epidemiology of high-risk human papillomavirus (HR-HPV) and co-infecting reproductive tract bacterial pathogens in underserved regions is increasingly important. We investigated the prevalence and co-infection patterns of HR-HPV and bacterial pathogens (Chlamydia trachomatis, Ureaplasma urealyticum, Neisseria gonorrhoeae) among rural women in Hainan, and examined their associations with cervical epithelial lesions to inform optimized risk stratification for this population. Within a screening cohort of 8,925 women in Hainan (May-October 2025), we employed a nested case-control design enrolling 869 HR-HPV-positive cases and 473 negative controls, which were randomly selected from HR-HPV-negative women, with age adjustment applied in statistical analyses. Participants underwent genotyping for HR-HPV and bacterial sexually transmitted infections (C. trachomatis, U. urealyticum, N. gonorrhoeae). Cervical abnormalities were assessed via ThinPrep Cytologic Test and subsequent histopathology. HR-HPV infection was associated with older age and lower educational attainment (p < 0.001). Among HR-HPV subtypes, single-type HR-HPV infection predominated (83.08%). U. urealyticum was the most prevalent reproductive tract bacterial pathogen (45.75%) and was more frequently co-detected in HR-HPV-positive women than in controls (p < 0.001). Network analysis further identified U. urealyticum as a central hub, showing strong co-occurrence with HR-HPV52 and HR-HPV58. Clinically, C. trachomatis was independently associated with higher odds of atypical squamous cells of undetermined significance (aOR = 2.82, p = 0.025), whereas U. urealyticum was associated with an increased risk of cervical intraepithelial neoplasia grade 1 (aOR = 1.79, p = 0.040). This study highlights a distinct co-infection ecosystem centered on U. urealyticum in rural women, where C. trachomatis and U. urealyticum drive differentiated risks for early cervical lesions. Consequently, public health strategies should prioritize this underrepresented rural population. Integrating targeted bacterial STIs testing into HPV screening could significantly enhance risk stratification and intervention efficiency in settings with limited resources.

📚 EuropePMCmostrando 200

2026

Non-invasive host transcriptome and HPV oncogene expression map the molecular landscape of HPV-driven cervical lesions.

PloS one
2026

Cytological versus histological results in ASCUS cervical dysplasia - a retrospective study.

Ceska gynekologie
2026

High-risk HPV and bacterial STIs in a primary screening population in rural Hainan, China: prevalence, co-infection, and association with cervical abnormalities.

Frontiers in public health
2026

Unilateral cervical carcinoma in a septate uterus with double cervix: A case report and literature review.

Gynecologic oncology reports
2026

Reproductive outcomes after surgical correction of congenital obstructive genital tract anomalies: A systematic review and quantitative pooled analysis of published data.

European journal of obstetrics, gynecology, and reproductive biology
2026

Microbiome, Human Papillomavirus and Cervical Carcinogenesis.

Current topics in microbiology and immunology
2026

Interval Vaginal Delivery of Term Twins From Bilateral Horns of a Uterus Didelphys: Insight Into Labor Initiation and Progression.

The journal of obstetrics and gynaecology research
2026

Impact of commune level social inequalities on time to diagnosis and follow-up in women with high-grade cervical lesions in Isère, France: Evidence from the French cervical cancer screening program.

Preventive medicine reports
2026

Relationship between Multiple HPV Infections and Cervical Cytology: Single Center Experience.

Chonnam medical journal
2026

Immunohistochemical expression of Ki-67, estrogen receptor, and human epidermal growth factor receptor 2 in p16-positive premalignant and malignant cervical squamous lesions: associations with clinicopathological parameters.

Ewha medical journal
2026

Prostaglandins versus transcervical balloon for induction of labor for fetal growth restriction: study protocol for a randomized, multicenter, open-label, superiority trial (PROBIN).

BMC pregnancy and childbirth
2026

Prevalence, clinical profile, and associated anomalies with women with Mayer-Rokitansky-Küster-Hauser syndrome in a tertiary care center: A cross-sectional study.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
2026

The effect of a cervical testing campaign on incarcerated females- a repeated cross-sectional study in Norwegian prisons.

BMC women's health
2026

Discovering the abnormalities and functional importance of ferroptosis-related molecules in cervical cancer.

International journal of medical sciences
2026

Infertility in an American Quarter Horse mare with cervical duplication.

Journal of equine veterinary science
2026

Lessons Learned From Evaluation of a Human Papillomavirus Screening Pilot in Uzbekistan.

JCO global oncology
2026

Preoperative ultrasound assessment for surgical risk management in patients with a placenta previa and a history of cesarean delivery.

American journal of obstetrics and gynecology
2026

Clinical and Imaging Features of Gastric-Type Endocervical Adenocarcinoma: A Report of 9 Cases with Literature Review.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
2026

Successful pregnancy after reconstructive surgery for a woman with complete cervical and vaginal agenesis - a case report and literature review.

Human fertility (Cambridge, England)
2025

A Rare Case of Müllerian Agenesis With a Giant Tumor Arising From Uterine Remnants.

Case reports in obstetrics and gynecology
2025

Prognostic Value of Post-Cerclage Transvaginal Ultrasound Parameters in Predicting Spontaneous Preterm Birth.

Medicina (Kaunas, Lithuania)
2025

Recognizing an Incarcerated Gravid Uterus When the Cervical Canal Is Absent on Transvaginal Ultrasound.

Cureus
2025

Vaccine-preventable HPV burden and cervical abnormalities in women during 2022-2024 Octobre Rose campaigns in Libreville.

Nature communications
2026

Outcomes of Women Who Underwent Hysterectomy for Persistent Cervical Dysplasia.

Journal of lower genital tract disease
2025

Use of artificial intelligence in the diagnosis of alterations in cervical cytology: A university population-based observational study.

Biomedica : revista del Instituto Nacional de Salud
2025

Obstetric Outcome After Trachelectomy for Cervical Cancer Without Uterine Artery Preservation.

The journal of obstetrics and gynaecology research
2026

Optimising management of women with HPV (not 16/18): Findings from a national HPV screening program.

Gynecologic oncology
2025

Retrospective analysis of cervical screening abnormalities in women with type 3 transformation zone without visible lesions.

PeerJ
2025

Effect of cervical changes on the cesarean scar topography after primary cesarean sections: an observational study.

BMC pregnancy and childbirth
2026

Risk Factors for Reoperation and Subsequent Uterine Preservation in Congenital Cervical Malformation.

Journal of minimally invasive gynecology
2025

Cytology and high-risk human papillomavirus testing to reduce colposcopies in women with postcoital bleeding.

Danish medical journal
2025

Clinicopathologic characteristics and prognostic outcomes of surgically treated neuroendocrine cervical carcinoma: A single institution retrospective analysis.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
2025

High risk HPV among HIV positive women with normal and abnormal cervical cytology in Bahir Dar, north west Ethiopia.

Scientific reports
2026

Triage and care for women with symptoms or diagnosis of pregnancy loss between 14 + 0 and 21 + 6 weeks' gestation.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
2026

Nanotechnology in gynaecological cancers: Biomedical perspectives on lipid-based drug delivery systems for targeted therapy.

International journal of pharmaceutics
2026

Cytomorphologic alterations, histologic correlates, and clinical importance of pap test evaluation in intrauterine device users.

Journal of the American Society of Cytopathology
2026

Controlled trial of cervical cancer screening frequency among human-papillomavirus-vaccinated women.

International journal of cancer
2025

A hybrid vision transformer with ensemble CNN framework for cervical cancer diagnosis.

BMC medical informatics and decision making
2026

The cervical cancer screening program in the North of Portugal: Outcomes after nearly two decades of coexistence with the human papillomavirus vaccine.

International journal of cancer
2025

Spinal Anomalies in MURCS Association: A Rare Case Report and Systematic Review of the Literature.

Congenital anomalies
2025

Extra-Amniotic Bovine Foetus With Aplasia of the Posterior Body: A Case Report.

Reproduction in domestic animals = Zuchthygiene
2025

Evaluation of the efficacy of topical photodynamic therapy against cervical HPV infection.

Photodiagnosis and photodynamic therapy
2025

Predictive Factors for Cervical Intraepithelial Neoplasia in Women with Abnormal Cytology According to Human Papillomavirus Genotype: An Observational Study.

International journal of molecular sciences
2025

Prevalence of cervical cytology abnormalities and its correlation with human papillomavirus infection: a single- institution five-year experience.

Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina
2025

Human papillomavirus prevalence and genotype distribution among 30,147 screened women and 3,362 cervical cancer patients in China: a retrospective study.

Virology journal
2025

MOLECULAR DETECTION OF HIGH RISK HUMAN PAPILLOMA VIRUS SUBTYPES IN CERVICAL SMEARS AMONG SUDANESE WOMEN.

Georgian medical news
2025

Immediate risk and 5-year cumulative risk of high-grade cervical lesions in high-risk HPV-positive patients with minor cytological abnormalities: a retrospective single-center study in China.

BMC cancer
2026

High-risk HPV genotype distribution and prevalence in cervical swabs from Western Turkey.

Diagnostic microbiology and infectious disease
2025

Early-third-trimester uterine rupture in an unscarred primigravida with a didelphic uterus: a case report.

Journal of medical case reports
2026

Human papillomavirus driving cervical cancer: A mathematical model with persistent infection, cancer progression, and spontaneous remission.

Journal of theoretical biology
2025

Barriers to cervical cancer prevention and triage strategies: a study of knowledge, attitudes, and p16/Ki-67 dual-staining utility among high-risk women in Tuoli and Fuyun counties, Xinjiang.

PeerJ
2025

Comparative Cytokine and Histology Studies on HPV and Other Viral Vaccinations: No Pathogenicity of HPV Vaccine Adjuvants.

Cancer science
2025

The consequences of traditional cervical cauterization on cervical integrity and pregnancy: a cross-sectional study.

Scientific reports
2025

Performance Evaluation of the Aptima hrHPV Nucleic Acid Amplification and Papanicolaou Co-Testing in Cervical Cancer Screening: Insights from a Diverse Population-Based Retrospective Study.

The Journal of molecular diagnostics : JMD
2025

CerviNet: A Novel Approach for Cervical Cancer Classification Using Pap-Smear Images.

Journal of computational biology : a journal of computational molecular cell biology
2025

Usage of cervical cerclage in pregnancy with Mullerian anomalies and cervical insufficiency: A case report.

SAGE open medical case reports
2025

Cervical Deciduosis in Early Pregnancy Mimicking Malignancy: A report of two cases.

Sultan Qaboos University medical journal
2025

Beyond the transformation zone: Outcomes in the management of CGIN over five years.

European journal of obstetrics, gynecology, and reproductive biology
2026

Diagnostic Value of Ultrasound in Primary Cervical Ewing's Sarcoma: Two Case Reports and Literature Review.

Journal of clinical ultrasound : JCU
2025

Cervical pessary for preterm-birth prevention among pregnant women with a short cervix: A prospective cohort study.

Taiwanese journal of obstetrics &amp; gynecology
2025

Preterm birth rates and risk factors among women with cervical incompetence undergoing prophylactic cerclage: a systematic review and meta-analysis.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
2025

Cervical cancer risk and high-risk HPV types distribution in Saudi Arabia: Trends from a national laboratory-based study.

Saudi medical journal
2025

Cervical cytology-based screening identifies trichomonas vaginalis as a significant correlate of non-16/18 high-risk human papillomavirus infection in high-altitude tibetan agro-pastoral communities: A cross-sectional study of 62,657 women.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2025

Cervical Cancer Screening Using Papanicolaou Smear and Visual Inspection With Acetic Acid and Their Correlation With Colposcopy.

Cureus
2026

Laparoscopic Management of Cervical Agenesis: A Rare Case Report.

Journal of minimally invasive gynecology
2025

Comparative study of pap smear and polymerase chain reaction tests for human papillomavirus screening in Bahrain.

Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit
2025

High-risk human papillomavirus (hr-HPV) prevalence and abnormal cervical cytology in rural high-altitude communities: a population-based cross-sectional study in the Southern Tibetan Plateau, China (2023-2024).

Virology journal
2025

Cervical screening approach of self-collection, point-of-care HPV testing, and same-day colposcopy among Aboriginal and Torres Strait Islander women in remote Western Australia (the PREVENT Project): an implementation study.

The Lancet. Public health
2025

Development of palmatine chloride-loaded chitosan nanoparticles for enhanced and safe cervical cancer therapy.

International journal of biological macromolecules
2025

The Ex-utero intrapartum treatment procedure: a narrative review.

Frontiers in pediatrics
2025

New histopathological and molecular findings in gynecological cancers.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
2025

The Manchester Procedure as a Uterine-Preserving Alternative for Uterine Prolapse Due to Cervical Elongation: A Short- and Mid-Term Clinical Analysis.

Medicina (Kaunas, Lithuania)
2025

Whole-disease-cycle management in a collaborative care model based on the WeChat platform: A case report.

Medicine
2025

Co-Infection Patterns of Beta, Gamma, and Alpha HPV Types in Cervical and Anal Sites in HIV-Positive Women.

Journal of medical virology
2025

The prevalence and clinical relevance of cervical abnormalities after an amputation of the cervix as part of prolapse surgery: a cross-sectional study.

Archives of gynecology and obstetrics
2025

Accuracy and acceptability of self-sampling HPV testing in cervical cancer screening: a population-based study in rural Yunnan, China.

Scientific reports
2025

Boric Acid Suppresses Cell Survival by Triggering Endoplasmic Reticulum Stress-Induced Autophagy in Cervical Cancers.

Journal of cellular and molecular medicine
2025

Laparoscopic transabdominal cerclage in a patient with a complete septate uterus and duplicated cervices.

Fertility and sterility
2025

Risk assessment in a Chinese cohort of 96 318 females undergoing opportunistic cervical cancer screening.

The oncologist
2025

Attention-Based Whole-Slide Image Compression Achieves Pathologist-Level Prescreening of Multiorgan Routine Histopathology Biopsies.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
2025

Evaluation of Cervical Cancer Screening in Japan: Challenges and Future Directions for Negative Intraepithelial Lesion or Malignancy/High-Risk Human Papillomavirus Positive Case Management.

Current oncology (Toronto, Ont.)
2025

Reproductive disorders in Simmental cattle: Enhancing fertility through a hormonal protocol.

Open veterinary journal
2025

What trans-vaginal ultrasound parameters are better correlated with a shorter labor induction to vaginal delivery interval? A prospective observational cohort study.

The journal of maternal-fetal &amp; neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
2025

Cytomorphological Characteristics of Cervical Scrape from Controlled and Uncontrolled Diabetes Mellitus Patients Attending Tertiary Healthcare, Kenya.

Acta cytologica
2025

Navigating Complexity: Advanced Visualization for Müllerian Anomalies and its Implications for Diagnoses and Surgical Planning.

Journal of pediatric and adolescent gynecology
2025

Comparison and correlations between findings of hysteroscopy and vaginal color Doppler ultrasonography for detection of uterine abnormalities in patients with recurrent implantation failure.

Open medicine (Warsaw, Poland)
2025

EXPERIENCE OF IMPLEMENTING DIGITAL TELEMEDICINE TECHNOLOGIES TO IMPROVE ACCESS TO CERVICAL CANCER SCREENING IN RURAL AREAS OF THE REPUBLIC OF KAZAKHSTAN.

Georgian medical news
2025

Surgical and reproductive outcomes of hysteroscopic metroplasty for complete septate uterus with or without associated cervical anomalies and/or vaginal septa.

European journal of obstetrics, gynecology, and reproductive biology
2025

Endometriosis in patients with female genital tract congenital anomalies: A retrospective cohort study.

Journal of gynecology obstetrics and human reproduction
2025

Assessment of 5 miscarriages with transcervical embryoscopy.

Fertility and sterility
2025

Mayer-Rokitansky-Kuster-Hauser syndrome.

Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia
2025

Implementing 100% quality control in a cervical cytology workflow using whole slide images and artificial intelligence provided by the Techcyte SureView™ System.

Cancer cytopathology
2025

Unilateral Inguinal Swelling in a Young Female: An Unusual Presentation of MURCS.

Journal of human reproductive sciences
2025

Deep learning-based decision support system for cervical cancer identification in liquid-based cytology pap smears.

Technology and health care : official journal of the European Society for Engineering and Medicine
2025

Monocytes and parturition: Linking prolonged labor to immune dysregulation.

Medicine
2025

Human papillomavirus (HPV) infection and liquid-based cytologic tests among cervical screening participants in Shannan City, Tibet, China, during 2021-2022.

BMC infectious diseases
2025

Incidence and risk factors of postpartum urinary retention following cesarean section: a retrospective nationwide inpatient sample database study.

BMC women's health
2025

Prevalence of HPV infection and cervical lesions among women with pelvic organ prolapse and implications for preoperative evaluation.

BMC cancer
2025

Outcomes associated with large loop excision of the cervical transformation zone in women 60-64 years of age: A population-based register study from Denmark.

Acta obstetricia et gynecologica Scandinavica
2025

Antegrade genitography - A new diagnostic modality of obstructive abnormalities in the female reproductive tract.

Journal of pediatric urology
2025

Uterus didelphys bicollis bicolpos-a case report.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
2025

Clinical practice in office hysteroscopy.

Obstetrics &amp; gynecology science
2025

Prevalence and risk factors of high-risk HPV and cervical abnormalities in HIV-positive women in Bali, Indonesia.

BMC infectious diseases
2025

Gynecologic health of women with multiple sclerosis: An overview on the current status and findings of Pap tests in a low-income setting.

PloS one
2025

The role of serum inflammatory markers in determining the severity of cervical lesions.

The journal of obstetrics and gynaecology research
2025

Acute urinary retention in an adolescent female with Herlyn-Werner-Wunderlich syndrome.

Annals of medicine and surgery (2012)
2025

Human Papillomavirus Prevalence and Genotype Distribution Among Women With Cervical Cytological Abnormalities in Urumqi, Xinjiang, China.

Diagnostic cytopathology
2025

Uterine hyperstimulation in cervical ripening with oral misoprostol versus dinoprostone vaginal pessary: A real-life single-center descriptive study.

Journal of gynecology obstetrics and human reproduction
2025

Gracilaria edulis-mediated silver nanoparticles as a targeted strategy for cervical cancer with integrated toxicity evaluation in zebrafish.

Bioorganic chemistry
2025

Characterization of human papillomavirus genotypes infections in patients with cervical lesions and cervical cancer in Urumqi, Xinjiang from 2016 to 2023.

Virology journal
2025

Persistence and clearance rates of human papillomaviruses in a cohort of women treated or not treated for cervical dysplasia in northwest Ethiopia.

Scientific reports
2025

Imaging and Diagnostic Challenges in an 11-Year-Old Girl with Vaginal Agenesis: A Case Report.

The American journal of case reports
2025

Guideline-Concordant Surveillance After Treatment for High-Grade Cervical Dysplasia.

Obstetrics and gynecology
2025

How MRI imaging for an ovarian cyst led to diagnosis of short cervix.

BMC pregnancy and childbirth
2025

Repair of Traumatic Uterine Avulsion of a Gravid Uterus.

Obstetrics and gynecology
2025

Waikato Environment for Knowledge Analysis (WEKA) as a Data Analysis Method Identifying Potential Hematological Parameters for Early Diagnosis of Cervical Cancer.

In vivo (Athens, Greece)
2025

HTLV-1 Infection and Cervicovaginal Susceptibility to High-Risk HPV: Findings from Women Living with HTLV-1 in Salvador, Brazil.

Viruses
2025

Impact of Smoking on Cervical Histopathological Changes in High-Risk HPV-Positive Women: A Matched Case-Control Study.

Medicina (Kaunas, Lithuania)
2025

Aptima HPV E6/E7 mRNA and cytology cross-sectional performance as primary screening tests for detection of high-grade cervical lesions in HIV positive and negative women in South Africa.

Journal of medical screening
2025

Cervical cancer screening: comparative study of human papillomavirus detection between cervical cytology and urine samples.

BMC women's health
2025

"High incidence of abnormal pap smears and low awareness of cervical cancer among women in Rewa, Madhya Pradesh, India: Implications for screening and education".

Cancer epidemiology
2025

Association between conditions affecting the vaginal portion of the cervix or the cranial portion of the vagina and reproductive performance in lactating dairy cows.

Theriogenology
2025

Preconception Counseling in the Setting of Unilateral Cervical Atresia in a Patient with Uterus Bicornuate Bicollis: A Case Report.

Journal of pediatric and adolescent gynecology
2025

Vulvar inspection at the time of cervical cancer screening: European Society of Gynaecological Oncology (ESGO), International Society for the Study of Vulvovaginal Disease (ISSVD), European College for the Study of Vulval Disease (ECSVD), and European Federation for Colposcopy (EFC) consensus statements.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
2025

Targeted removal of a small gestational sac in early pregnancy loss via hysteroscopy: distinguishing the true gestational sac from two pseudogestational sacs and a submucosal fibroid.

Fertility and sterility
2025

Human Papillomavirus Infection and Cytological Atypia in Female Allogeneic Hematopoietic Stem Cell Transplantation Recipients.

Transplantation
2025

Nanoparticle-based colorimetric assays for early and rapid screening of the oncogenic HPV variants 16 and 18.

Clinica chimica acta; international journal of clinical chemistry
2025

Primary versus secondary recurrent pregnancy losses: Clinical findings and live birth rate after comprehensive work-up and personalized management.

Acta obstetricia et gynecologica Scandinavica
2025

Postpartum haemorrhage following vaginal delivery: a comprehensive analysis and development of predictive models for aetiological subgroups in Chinese women.

BMJ open
2025

Prevalence rate of high-grade cytological lesions of the cervix in women aged under 25 years in French Guiana.

European journal of obstetrics, gynecology, and reproductive biology
2025

Study protocol for key interventions to improve the follow-up adherence postcervical precancerous lesion treatment in Ethiopia: a pragmatic randomised controlled trial.

BMJ open
2025

Association of female genital schistosomiasis and human papillomavirus and cervical pre-cancer: a systematic review.

BMC women's health
2025

Comparative efficacy of HPV 16/18 DNA and E6/E7 mRNA testing in detecting high-grade cervical lesions (CIN2+) in women with cervical biopsies.

Diagnostic microbiology and infectious disease
2024

Performance of HPV Self-Sample Collected by a Novel Kit in Comparison with Clinician Collected Sample for Cervical Cancer Screening.

Asian Pacific journal of cancer prevention : APJCP
2025

Image Quantification Analysis of Cytoplasmic Mucin and Interpretation of Mucin Color in Lobular Endocervical Glandular Hyperplasia.

Acta cytologica
2024

Multifaceted Cervical Endometriosis: A Post-Surgical Diagnosis in a Complex Gynecological Case.

The American journal of case reports
2025

The Pivotal role of hysteroscopy in diagnosing subtle uterine lesions in infertile patients: Seeing the unseen can make the difference.

European journal of obstetrics, gynecology, and reproductive biology
2024

Prevalence of HPV infection and anal and cervical cytological abnormalities in transgender people at a referral service in Vitória, Espírito Santo state, Brazil, between 2018 and 2021.

Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil
2024

The performance of JAM3/PAX1 methylation in the diagnosis of high-grade squamous intraepithelial lesions for women with high-risk HPV infection.

BMC cancer
2024

Assessment of a colposcopic scoring system (Swedescore) to reduce the number of cervical biopsies: a protocol for a clinical multicentre non-randomised intervention study in Denmark.

BMJ open
2025

Poor Performance of Applicator Tampon-Based Self-Collection for Liquid-Based Cytology Among Women Attending a Tertiary Hospital in South Africa.

Diagnostic cytopathology
2025

Human papillomavirus genotype-specific prevalence and infection risks: a 10-year population-based study from the United States.

Journal of the National Cancer Institute
2024

Declining Prevalence of Human Papillomavirus Co-Infections Among Young Japanese Women With Cervical Cancer and Its Precursors.

Journal of medical virology
2024

Value of intraoperative post-conisation human papillomavirus testing in predicting residual or recurrence after treatment with a loop electrosurgical excision procedure in women with HR-HPV positive and cervical high-grade squamous intraepithelial lesion.

BMC cancer
2025

Yield of endocervical curettage in detecting cervical intraepithelial neoplasia grade 2 or higher during colposcopy: A prospective, cross-sectional study.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
2024

[Value of laser therapy, photodynamic therapy, and follow-up observation in the management of cervical low-grade squamous intraepithelial lesions: a prospective cohort study].

Zhonghua fu chan ke za zhi
2025

High burden of human papillomavirus and premalignant cervical lesions among women starting HIV treatment in KwaZulu-Natal, South Africa.

Sexually transmitted infections
2024

Cervical intraepithelial neoplasia and cervical cytology in pregnancy.

Journal of pathology and translational medicine
2024

Spectrum of Female Hypospadias: A Case Series.

Cureus
2024

Hematological changes in women with cervical cancer before and after cancer treatment: retrospective cohort study.

Scientific reports
2024

Prediction of high-grade cervical precancerous abnormalities: The role of personal factors, vaginal microflora, sexually transmitted infections, and high-risk human papillomavirus.

PloS one
2025

The role of colposcopy in HPV vaccination era.

Minerva obstetrics and gynecology
2025

Analysis of the sensitivity of high-grade squamous intraepithelial lesion Pap diagnosis and interobserver variability with the Hologic Genius Digital Diagnostics System.

Cancer cytopathology
2025

Retrospective analysis of HPV infection: Cotesting and HPV genotyping in cervical cancer screening within a large academic health care system.

Cancer cytopathology
2024

Malignant peripheral nerve sheath tumor of the cervix in an adolescent with neurofibromatosis type 1: A case report and review of literature.

The journal of obstetrics and gynaecology research
2024

Risk factors for positive cervical cytology during early pregnancy screening and awareness of positive cytological results in Japan: a report from the Pregnant Women Health Initiative.

The Journal of international medical research
2024

Prevalence of cervical dysplastic lesions in cervical smears from Baghdad city: a single centre study.

JPMA. The Journal of the Pakistan Medical Association
2025

Transvaginal sonographic screening of abnormal intra-amniotic structure around internal cervical os at 18-21+6 weeks of gestation.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
2024

Enhancing pap smear image classification: integrating transfer learning and attention mechanisms for improved detection of cervical abnormalities.

Biomedical physics &amp; engineering express
2024

Identification and functional characteristics of CHD1L gene variants implicated in human Müllerian duct anomalies.

Biological research
2024

The Correlation of Hysteroscopy and Histopathology in Evaluating Abnormal Uterine Bleeding: Observations From a Tertiary Care Center.

Cureus
2025

Role of ultrasound in diagnosing gravid uterine incarceration.

Journal of clinical ultrasound : JCU
2025

Traditional vs novel out-of-office method for collecting cytology and HPV DNA - a comparative study.

Ginekologia polska
2024

Cervical cytology in endometrial cancer patients with Lynch syndrome: opportunities for early detection and limitations.

Journal of the American Society of Cytopathology
2024

The association of inflammatory changes of the uterus and chorioamniotic membranes with different types of labor activity anomalies.

Wiadomosci lekarskie (Warsaw, Poland : 1960)
2024

The level of expression of HPV16 early transcripts is not associated with the natural history of cervical lesions.

Journal of medical virology
2024

The Impact of Tamoxifen Usage in Breast Cancer Patients on the Development of Histopathological Lesions in the Cervix Uteri.

Medicina (Kaunas, Lithuania)
2024

Impact of management guidelines for abnormal cervical cytology on colposcopy procedure rates among young women.

Gynecologic oncology
2024

Undiagnosed Uterine Didelphys, Concomitant Right Renal Agenesis, and Left Nephrolithiasis in a Primigravida With Breech Pregnancy: A Case Report.

Cureus
2024

Tubal replacement of cervix for treatment of type II vaginal atresia complicated with cervical dysplasia: a case report.

The Journal of international medical research
2024

Prevalence and genotype distribution of HPV combined with cervical pathological results in women from Sichuan, China: A cross-sectional study based on post-vaccination period 2019 to 2023.

Cancer medicine
2024

A Full-Term Pregnancy in a Patient With Uterus Didelphys.

Cureus
2024

The protective effect of vinpocetine against Estradiol-benzoate induced cervical hyperkeratosis in female rats via modulation of SIRT1/Nrf2, and NLRP3 inflammasome.

Scientific reports
2025

Clinical significance of atypical glandular cells on cytology: 10 years' experience of a colposcopic referral center.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)
2024

Uterus Transplant in Women With Absolute Uterine-Factor Infertility.

JAMA
2024

Potential anatomical determinants of retrograde menstruation: a comprehensive narrative review.

Reproductive biomedicine online
2024

HPV specificity and multiple infections and association with cervical cytology in Chongqing, China: a cross-sectional study.

BMC infectious diseases
2024

Cervicovaginal microbiome, high-risk HPV infection and cervical cancer: Mechanisms and therapeutic potential.

Microbiological research
2024

High risk human papillomavirus prevalence and genotype distribution in Reunion Island.

European journal of obstetrics, gynecology, and reproductive biology
2025

Epigenome-wide differential methylation and differential variability as predictors of high-grade cervical intraepithelial neoplasia (CIN2+).

American journal of epidemiology
2024

Prevalence of sexually transmitted infections and human papillomavirus in cervical samples from incarcerated women in São Paulo, Brazil: a retrospective single-center study.

Frontiers in public health
2024

Association of congenital uterine anomaly with abnormal placental cord insertion and adverse pregnancy complications: a retrospective cohort study.

The journal of maternal-fetal &amp; neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
2025

Comparison between 3D-Enhanced Conventional Pelvic Ultrasound and Magnetic Resonance Imaging in the Evaluation of Obstructive Müllerian Anomalies and Its Concordance with Surgical Diagnosis.

Journal of pediatric and adolescent gynecology
2024

Cisplatin-induced bone marrow failure in an adult patient with Fanconi anemia.

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
2024

Promise and Perils of Primary HPV Testing.

Cancer epidemiology, biomarkers &amp; prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
2024

HPV Extended Genotyping to Triage Abnormal Cervical Cancer Screens-Balancing the Harms and Benefits of an Additional Triage Test before Direct Colposcopy Referral.

Cancer epidemiology, biomarkers &amp; prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
2024

[Trans-YOLOv5: a YOLOv5-based prior transformer network model for automated detection of abnormal cells or clumps in cervical cytology images].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University
2024

Diagnostic cervical excision in patients with HPV positivity, cytological abnormalities- and preoperative cervical stenosis.

BMC women's health
2025

Analysis of Immunological Biomarkers Associated With Rejection After Uterus Transplantation in Human.

Transplantation
2024

Cervical cancer screening by cytology and the burden of epithelial abnormalities in low resource settings: a tertiary-center 42-year study.

BMC women's health
2024

Monitoring mouse papillomavirus-associated cancer development using longitudinal Pap smear screening.

mBio
2024

Developmental and heritable genetic defects induced in mice by municipal landfill leachate.

Chemosphere
2024

Pegylated recombinant human granulocyte colony-stimulating factor for primary prophylaxis of neutropenia in patients with cervical cancer receiving concurrent chemoradiotherapy: a prospective study.

BMC cancer
2024

Management of congenital cervical atresia with vaginal aplasia: A case report and review of the literature.

International journal of surgery case reports
2024

Cervical cancer screening integrated in routine clinical care of women with HIV.

AIDS (London, England)
2024

Application of probiotics in cervical cancer infections to enhance the immune response.

Microbial pathogenesis
2024

The predictive value of serum inflammatory markers for the severity of cervical lesions.

BMC cancer
2024

Cytology-histology correlation of atypical glandular cells on cervical Papanicolaou tests: A study of 628 cases.

Journal of the American Society of Cytopathology
2024

Human papillomavirus infection among adolescents living with HIV: a focus on prevention.

Current opinion in HIV and AIDS
2024

The Swedish Cervical Screening Cohort.

Scientific data

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Non-invasive host transcriptome and HPV oncogene expression map the molecular landscape of HPV-driven cervical lesions.
    PloS one· 2026· PMID 41855211mais citado
  2. Discovering the abnormalities and functional importance of ferroptosis-related molecules in cervical cancer.
    International journal of medical sciences· 2026· PMID 41583517mais citado
  3. Infertility in an American Quarter Horse mare with cervical duplication.
    Journal of equine veterinary science· 2026· PMID 41564982mais citado
  4. Cytological versus histological results in ASCUS cervical dysplasia - a retrospective study.
    Ceska gynekologie· 2026· PMID 41841534mais citado
  5. High-risk HPV and bacterial STIs in a primary screening population in rural Hainan, China: prevalence, co-infection, and association with cervical abnormalities.
    Frontiers in public health· 2026· PMID 41810296mais citado

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:180145(Orphanet)
  2. MONDO:0015845(MONDO)
  3. GARD:20186(GARD (NIH))
  4. Q17001349(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Aplasia e agenesia cervical uterina
Compêndio · Raras BR

Aplasia e agenesia cervical uterina

ORPHA:180145 · MONDO:0015845
CID-10
Q51.5 · Agenesia e aplasia do colo do útero
CID-11
MedGen
UMLS
C5190813
Wikidata
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