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Ganglioglioma
ORPHA:251949CID-10 · D33.0CID-11 · 2A00.21DOENÇA RARA

O glioma angiocêntrico (GA) refere-se a um tumor neuroepitelial raro em que as células malignas superficiais do cérebro envolvem os vasos cerebrais; é mais comummente encontrado em crianças e adultos jovens. Inicialmente identificado em 2005 pelo Dr. Ming-Tseh Wang e a sua equipa da Universidade do Texas em Austin, o GA foi classificado como um tumor de Grau I na Classificação de Tumores do Sistema Nervoso Central da OMS de 2007 devido ao seu comportamento clínico benigno, baixo índice de proliferação e propriedades curativas. O GA afeta principalmente crianças e adultos jovens com uma idade média de diagnóstico inicial de 16 anos. Mais de 85% dos pacientes com GA sofrem de crises convulsivas intratáveis desde a infância, especialmente epilepsia parcial.

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Introdução

O que você precisa saber de cara

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Tumor cerebral raro composto por células neuronais e gliais. Geralmente benigno, pode causar convulsões, dores de cabeça e déficits neurológicos. O tratamento varia de observação a cirurgia, dependendo do tamanho e localização.

Pesquisas ativas
6 ensaios
15 total registrados no ClinicalTrials.gov
Publicações científicas
1.407 artigos
Último publicado: 2026 May
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SUS: Sem cobertura SUSScore: 0%
CID-10: D33.0
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Total histórico1.407PubMed
Últimos 10 anos200publicações
Pico202460 papers
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2026Hoje · 2026🧪 1996Primeiro ensaio clínico📈 2024Ano de pico
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Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

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15 ensaios clínicos encontrados, 6 ativos.

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Publicações mais relevantes

Timeline de publicações
608 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 608

#1

Use of tumor treating fields for a malignant brain tumor in a pregnant woman: Case report.

Brain & spine2026

Brain tumors diagnosed during pregnancy are exceptionally rare, and their clinical progression is not yet fully understood. Managing intracranial tumors during pregnancy necessitates a specialized approach, balancing neuro-oncological considerations with obstetric concerns to evaluate therapeutic options effectively.Tumor Treating Fields (TTF) therapy is a non-invasive, regionally-applied, anti-cancer treatment modality approved for adults with newly diagnosed and recurrent glioblastoma. To date, there is no data on the safety and efficacy of TTF therapy in pregnant patients harbouring malignant brain tumors. To describe a case of TTF-use during pregnancy and provide a first insight into its feasibility. We describe the first reported case of a pregnant women treated with TTF. Medical records and imaging data were analysed. Relevant literature concerning the management of malignant brain tumors in pregnancy was reviewed. The patient diagnosed with a posterior fossa high-grade anaplastic ganglioglioma (CNS WHO grade 3-4) received surgical resection followed by radiotherapy with fetal shielding combined with TTF therapy during pregnancy. Since TTF therapy represents a topical treatment without systemic application, we suggest it as a feasible option for pregnant patients diagnosed with malignant brain tumors.

#2

SpikeSpector software for MultiElectrode Arrays: Field potential analysis and spatial integration of electrophysiological and histological data.

Journal of neuroscience methods2026 Jan

The analysis of extracellular recordings from MultiElectrode Arrays (MEAs) is central to understanding the spatio-temporal dynamics of neuronal network activity in both physiological and pathological conditions. The detection of local field potential (LFP) events (of variable amplitude and shape, embedded in noisy, overlapping signals) remains particularly challenging when relying solely on visual detection or on automated tools. We developed SpikeSpector, a standalone, Python-based graphical user interface (GUI) that enables comprehensive LFP detection, precise manual curation, spatial mapping, and multimodal integration with immunohistochemical markers. SpikeSpector tools are described using MEA data recorded from a mouse brain slice harboring a ganglioglioma tumor. SpikeSpector enables users to refine automatically detected events through interfaces, improving the reliability of field potential identification in complex datasets. The platform offers visualization of voltage traces aligned to MEA layouts, customizable spike sorting and deletion tools, and quantification of waveform metrics such as amplitude, slope, and half-width. In addition, SpikeSpector introduces novel modules for correlating spike metrics with histological staining intensities, offering a powerful framework to spatially relate electrophysiological patterns to tissue architecture. Most existing tools for MEA analysis are limited by licensing costs, dependence on proprietary environments, and lack of integration with histological data, crucial for studies on brain diseases. Overall, SpikeSpector represents a flexible and accessible solution for bridging electrophysiological data with histological insights, enabling a more accurate and context-rich analysis of neural dynamics.

#3

A 6-year-old boy with left temporal lobe mass.

Brain pathology (Zurich, Switzerland)2026 Feb 11
#4

Multinodular and vacuolating neuronal tumor: molecular genetics and DNA methylation analysis of 12 cases.

The Journal of pathology2026 Mar 25

Multinodular and vacuolating neuronal tumor (MVNT) was recognized as a distinct neuronal tumor entity in the revision of the 2021 World Health Organization (WHO) Classification of Tumors of the CNS. In this study, we retrospectively analyzed 12 surgical cases, two of which exhibited ganglioglioma (GG)-like components. The cohort consisted of eight male and four female patients, with a median age of 31 years (age range: 18-53 years). Seizures were the most common clinical presentation, followed by headache and dizziness. Three patients were incidentally identified during physical examination. Ten tumors were located in the cerebral hemisphere, and the remaining two were found in the cerebellum and thalamus, respectively. Histopathological examination revealed clusters of neuroepithelial cells with large amphophilic vacuolated cytoplasm and eccentrically placed round nuclei containing prominent nucleoli. Immunohistochemically, these vacuolated cells were positive for OLIG2, MAP2, SYN and SOX10, and negative for GFAP and NEUN. DNA sequencing analysis identified no mutations in IDH1, IDH2, BRAF V600E, TERT promoter, or EGFR genes. Among the cohort, three cases harbored FGFR2 mutations, and FGFR2::INA gene fusion was detected in both MVNT and GG-like components. Two cases carried BRAF mutation, and one case exhibited MAP2K1 mutation. A novel BCAN::NTRK1 (exon 12-exon 9) gene fusion was identified in one case. DNA methylation profiling of eight cases revealed that none matched with a known CNS tumor type. Six cases formed a separate methylation cluster, suggesting a potential novel molecular subtype, while the remaining two cases exhibited transcriptional similarities to supratentorial pilocytic astrocytoma and rosette-forming glioneuronal tumor (RGNT), respectively. Postoperatively, all patients remained seizure free with no evidence of tumor progression. Only one patient died 16 months after surgery due to an unrelated traffic accident. © 2026 The Pathological Society of Great Britain and Ireland.

#5

Endoscopic management of cranial screw migration to cerebral aqueduct causing hydrocephalus.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2026 Mar 13

Intracranial migration of cranial fixation hardware is a rare complication of neurosurgical procedures, and migration into the ventricular system is exceedingly uncommon. When such migration leads to obstruction of cerebrospinal fluid (CSF) pathways, it can result in acute hydrocephalus requiring urgent intervention. A 10-year-old girl with a history of left frontotemporal ganglioglioma underwent synthetic Medpor cranioplasty for radiation necrosis-associated calvarial erosion. Intraoperatively, a fixation screw inadvertently plunged through a bone defect into an area of encephalomalacia. Postoperative imaging revealed the screw within the antrum of the left lateral ventricle. The patient remained asymptomatic and was discharged with close monitoring. At 3-week follow-up, she developed progressive headaches and fatigue. Neuroimaging demonstrated migration of the screw into the cerebral aqueduct, with resulting obstructive hydrocephalus. She underwent endoscopic third ventriculostomy and successful endoscopic removal of the screw, with full clinical recovery. This case illustrates a rare but serious complication of cranioplasty: delayed migration of a cranial screw into the ventricular system causing aqueduct obstruction. Endoscopic management allowed for both CSF diversion and removal of the foreign body and was associated with an excellent clinical outcome.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC711 artigos no totalmostrando 195

2026

Multinodular and vacuolating neuronal tumor: molecular genetics and DNA methylation analysis of 12 cases.

The Journal of pathology
2026

Endoscopic management of cranial screw migration to cerebral aqueduct causing hydrocephalus.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
2026

Molecular features in gangliogliomas: a systematic review.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
2026

Use of tumor treating fields for a malignant brain tumor in a pregnant woman: Case report.

Brain & spine
2026

Surgical outcomes and prognostic factors in epilepsy associated with low-grade brain tumors: a systematic review.

Neurosurgical review
2026

Awake Craniotomy in Pediatric Neurosurgery: A Case Report on a 12-Year-Old With Recurrent Ganglioglioma.

Cureus
2026

A 6-year-old boy with left temporal lobe mass.

Brain pathology (Zurich, Switzerland)
2026

Stereotactic radiosurgery for residual rosette-forming glioneuronal tumor: a case report and literature review.

Acta neurochirurgica
2026

Ganglioglioma in the spinal cord of a steer.

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
2026

Pediatric low-grade epilepsy-associated tumors (LEATS): neuroimaging review and genetics update.

Pediatric radiology
2026

Ganglioglioma mimicking a vestibular schwannoma: A rare entity of the cerebellopontine angle.

Neurocirugia
2026

Desmoplastic infantile ganglioglioma/astrocytoma: Expanding the molecular and morphological spectrum with a novel BRAF fusion.

Neuro-oncology advances
2026

An aggressive and recurrent pediatric ganglioglioma with unusual genotype: A rare case report.

Indian journal of pathology & microbiology
2026

The "long-tongue" sign: a new perspective on magnetic resonance imaging images of medullary ganglioglioma.

Quantitative imaging in medicine and surgery
2026

Nationwide registry-linked retrospective cohort study of Ganglioglioma in children and adults: Long-term follow-up of anti-seizure medication and mortality.

Seizure
2026

A Clinicoradiological Series of 39 Gangliogliomas: Insights into Surgical Outcomes and Prognostic Factors.

Neurosurgery practice
2026

Bone flap osteomyelitis following craniotomy in children: A 20-year audit.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
2026

[Polymorphous low-grade neuroepithelial tumor of the young: a molecular pathological study].

Zhonghua bing li xue za zhi = Chinese journal of pathology
2025

H3K27M- and BRAF V600E-Altered gliomas and glioneuronal tumors-clinico-pathologic and radiologic perspective in a cohort treated with targeted therapy.

Neuro-oncology advances
2025

Dabrafenib in pediatric patients with BRAF V600 mutation-positive high-grade glioma: Results from a phase 1/2a single-arm study.

Neuro-oncology practice
2025

The contribution of methylation profiling in neuropathological diagnosis of central nervous system tumors in children, adolescent and young adults.

Pathologica
2025

Suprasellar desmoplastic infantile astrocytoma and ganglioglioma: an institutional series report and a clinical summary of this rare tumor.

Frontiers in oncology
2025

Polymorphous low-grade neuroepithelial tumor of the young: case report and literature review.

International journal of clinical and experimental pathology
2025

Failure of GLP-1 Agonist Therapy to Improve Weight in a 3-Year-Old Patient With Tumor-Related Obesity.

Case reports in pediatrics
2025

The analysis of TOP2A as a potential target for predicting the prognosis of brain glioma in the TCGA database and in single-center study.

Discover oncology
2025

A Rare Case of Intramedullary Spinal Cord Ganglioglioma with Scoliosis.

Journal of orthopaedic case reports
2025

Infant-Type Hemispheric Gliomas: A Review of Clinical, Radiologic, Histopathologic, and Molecular Features.

Journal of the National Comprehensive Cancer Network : JNCCN
2026

A Child with Epileptic Seizure: A Case of Significantly Enhanced MVNT.

Clinical neuroradiology
2026

SpikeSpector software for MultiElectrode Arrays: Field potential analysis and spatial integration of electrophysiological and histological data.

Journal of neuroscience methods
2025

Radiological diagnosis of calcified intra- and extra-ventricular ganglioglioma involving the lateral ventricle: A case-based review of a challenging and uncommon presentation.

Radiology case reports
2025

Desmoplastic infantile ganglioglioma and astrocytoma: A narrative review of the literature.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
2025

A comprehensive overview on gangliogliomas: experiences of a Brazilian cohort and review on the main topics.

Neurosurgical review
2025

Single-nucleus RNA sequencing: immature excitatory neurons and transformed glia build human BRAFV600E-negative gangliogliomas.

Brain communications
2025

From Tachycardia to Brain Tumor: An Unusual Evolution of Epilepsy.

Cureus
2025

A case of neurofibromatosis type 1 with neurofibromatosis type 1-related and neurofibromatosis type 1-unrelated tumors: a case report.

Journal of medical case reports
2026

An Emerging Pediatric CNS Tumor: Imaging Evaluation of H3K27M and BRAF V600E Comutated Midline Tumors.

AJNR. American journal of neuroradiology
2025

Cerebellar ganglioglioma mimicking the radiographic appearance of Lhermitte-Duclos disease: A case report and review of literature.

Radiology case reports
2025

Intracranial low-grade tumors with ALK rearrangement: diverse tumor types with shared molecular alterations.

Human pathology
2025

Brain tumours as an unrecognized etiology of infantile epileptic spasms syndrome (IESS): The role of resective epilepsy surgery.

Epilepsy & behavior reports
2026

Interhemispheric Transcallosal Transchoroidal Resection of a Third Ventricular Ganglioglioma: 2-Dimensional Operative Video.

Operative neurosurgery (Hagerstown, Md.)
2025

Multi-pronged analysis of pediatric low-grade glioma and ganglioglioma reveals a unique tumor microenvironment associated with BRAF alterations.

Brain pathology (Zurich, Switzerland)
2025

Identifying Tumefactive Demyelination on Synthetic MRI Myelin Maps.

Case reports in radiology
2025

Papillary Glioneuronal Tumor Located in the Subcortical White Matter With a Purely Solid Pattern: A Case Report.

Cureus
2025

VOPP1::EGFR fusion is associated with NFκB pathway activation in a glioneural tumor with histological features of ganglioglioma.

Acta neuropathologica communications
2025

Chordoid glioma of right lateral ventricle in young male: a case report.

Annals of medicine and surgery (2012)
2025

Unraveling BRAF alterations: molecular insights to circumvent therapeutic resistance across cancer types.

Cancer drug resistance (Alhambra, Calif.)
2025

BRAF V600E Mutation in Ganglioglioma: Impact on Epileptogenicity and Implications for Surgical Strategy.

European journal of neurology
2025

Case Report: Unresectable recurrent nasopharyngeal cancer treated with immuno oncology.

Frontiers in oncology
2025

Bilateral V600-E Mutant Ganglioglioma of the Optic Nerve and Entire Optic Pathway: Case Report and Literature Review.

Ophthalmic plastic and reconstructive surgery
2025

The Mickey Mouse's hand sign in brain MRI points out multinodular and vacuolating neuronal tumors in mesial temporal lobe structures.

Journal of neuro-oncology
2025

Malignant transformation of cervical ganglioglioma to glioblastoma in a pediatric patient: illustrative case.

Journal of neurosurgery. Case lessons
2025

Ganglioglioma in mature cystic teratoma of the ovary: Case report and review of the literature.

Gynecologic oncology reports
2025

Dorsally exophytic brain stem ganglioglioma extending to the foramen of Luschka: a case report.

Journal of medical case reports
2025

Progression and diagnostic challenges of desmoplastic infantile ganglioglioma in a non-infant: a case report with 5-year follow-up.

Frontiers in oncology
2025

Pharmacologic Management of Obesity in Neuro-Oncology: A Case Report.

Case reports in oncology
2024

Insights into epileptic aphasia: Intracranial recordings in a child with a left insular ganglioglioma.

Epilepsy & behavior reports
2025

Pediatric cerebral ganglioglioma epilepsy surgery: enhancing seizure outcomes through optimized resection applying high-field intraoperative magnetic resonance imaging.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
2025

Staged and combined resection of a posterior fossa ganglioglioma.

Surgical neurology international
2025

The Diagnostic Yield of Panel Versus Exome Sequencing to Identify Hereditary Cancer Disorders in Pediatric Cancer.

Journal of pediatric hematology/oncology
2025

Augmented reality (AR) in microsurgical multimodal image guided focal pediatric epilepsy surgery: Results of a retrospective feasibility study.

Brain & spine
2025

Clinical outcomes of adults with intracranial grade 1 and 2 ganglioglioma.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
2024

Three Years of Progression-free after Biopsy of BRAF V600E-negative Ganglioglioma in the Adult Brainstem: A Case Report and the Literature Review.

NMC case report journal
2024

BRAF inhibitor monotherapy in BRAFV600E-mutated pediatric low-grade glioma: a single center's experience.

Frontiers in oncology
2025

Neuropathology of focal epilepsy: the promise of artificial intelligence and digital Neuropathology 3.0.

Pathology
2025

Increased SOX10, p16, and Cyclin D1 Immunoreactivity Differentiates MAP Kinase-activated Low-grade Gliomas From Piloid Gliosis.

The American journal of surgical pathology
2024

Childhood desmoplastic ganglioglioma in an infant, radiological aspects to know.

Anales de pediatria
2024

The Imaging Appearance of EWSR1::PATZ1 Gene Fusion Central Nervous System Tumors.

Journal of the Belgian Society of Radiology
2024

Thalamic Ganglioglioma Treated With Radical Radiotherapy: A Rare Location and an Exclusive Form of Treatment.

Cureus
2024

[Ganglioglioma with an atypical histopathological phenotype or a new entity of the LEAT group?].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
2024

Child Neurology: Simple Motor Tics Associated With Thalamic Ganglioglioma.

Neurology
2025

Dysgraphia Following the Resection of a Left Parietal Glioma.

Acta neurochirurgica. Supplement
2024

Phenotypic and epigenetic heterogeneity in FGFR2-fused glial and glioneuronal tumours.

Neuropathology and applied neurobiology
2025

Uncommon occipital ganglioglioma in a child: The critical role of MRI in diagnosis and management.

Radiology case reports
2024

Anatomy-guided resections for paralimbic tumors in the temporo-insular region: combining tumor and epilepsy surgery concepts.

Frontiers in neurology
2024

Ganglioglioma with MAP2K1 Mutation and CDKN2A/B Homozygous Deletion: A Case Report.

British journal of hospital medicine (London, England : 2005)
2024

Infantile desmoplastic ganglioglioma with FCD: A case report.

Asian journal of surgery
2024

Surgical treatment of long-term epilepsy-associated tumors guided by stereoelectroencephalography.

European journal of medical research
2024

Epilepsy in LEAT and other brain tumors: A focused review.

Epilepsy & behavior : E&B
2024

WONOEP appraisal: The role of glial cells in focal malformations associated with early onset epilepsies.

Epilepsia
2024

A ganglioglioma versus a schwannoma: Which is in the sacral spine?

International journal of surgery case reports
2024

Seizure outcome in surgically treated pediatric gangliogliomas and dysembryoplastic neuroepitheliomas according to imaging and resection strategies.

Seizure
2025

Contralateral transcallosal transfalcine approach for bilateral intra-extraventricular anaplastic ganglioglioma via 'the trans-tumoral route': a technical case instruction.

British journal of neurosurgery
2024

The Role of Radiotherapy, Chemotherapy, and Targeted Therapies in Adult Intramedullary Spinal Cord Tumors.

Cancers
2024

Mesial temporal lobe epilepsy and hippocampal sclerosis associated with BRAFV600E mutant neurons in the Cornu Ammonis: an uncertain pathogenesis and a diagnostic challenge.

Free neuropathology
2024

Intra-axial Cortical-Based Tumour Presented as Homonymous Hemianopia in a Young Patient: A Diagnostic Dilemma.

Cureus
2024

Clinical presentation and magnetic resonance imaging findings of a spinal cord ganglioglioma in a 7.5-year-old, male, neutered German shepherd dog.

Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
2024

Focal cortical dysplasia type IIIb associated with a KRAS-mutant ganglioglioma.

Cancer genetics
2024

Desmoplastic infantile astrocytoma/ ganglioglioma in a pediatric onset multiple sclerosis patient: A case report.

Clinical case reports
2024

Genotype-relevant neuroimaging features in low-grade epilepsy-associated tumors.

Frontiers in neurology
2024

Fast Metabolic Glycan Labeling for Click-Labeling and Imaging of Sialoglycans in Living Acute Brain Slices from Mice and Human Patients.

Journal of the American Chemical Society
2024

Diffuse leptomeningeal glioneuronal tumor with distinct neuronal and glial components but identical diagnostic molecular and genetic features.

Neuropathology : official journal of the Japanese Society of Neuropathology
2024

NTRK-fused central nervous system tumours: clinicopathological and genetic insights and response to TRK inhibitors.

Acta neuropathologica communications
2023

Pediatric autoimmune retinopathy and optic neuropathy: a case report and a review of the literature.

Frontiers in ophthalmology
2024

Unraveling morphology, methylation profiling, and diagnostic challenges in BRAF-Mutant pediatric glial and glioneuronal tumors.

Neurosciences (Riyadh, Saudi Arabia)
2024

Imaging of pediatric glioneuronal and neuronal tumors.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
2024

Publisher Correction: Ganglioglioma deep transcriptomics reveals primitive neuroectoderm neural precursor‑like population.

Acta neuropathologica communications
2024

Long-term seizure outcome after epilepsy surgery of neuroglial tumors.

Frontiers in neurology
2024

[Clinicopathological characteristics of gangliogliomas with anaplastic morphology].

Zhonghua bing li xue za zhi = Chinese journal of pathology
2024

Low-grade glioma of the temporal lobe and tumor-related epilepsy in children.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
2024

Desmoplastic non-infantile ganglioglioma mimicking diffuse leptomeningeal glioneuronal tumor: precision diagnostics and therapeutic implications.

Acta oncologica (Stockholm, Sweden)
2024

CDC42BPA::BRAF represents a novel fusion in desmoplastic infantile ganglioglioma/desmoplastic infantile astrocytoma.

Neuro-oncology advances
2024

Incidence and survival characteristics of pediatric ganglioglioma from 2004 to 2018, with focus on infratentorial sites.

Neuro-oncology practice
2024

Diffuse Gliomas with FGFR3::TACC3 Fusion: Morphological and Molecular Features and Classification Challenges.

Cancers
2024

Ganglioglioma with anaplastic/high-grade transformation: Histopathologic, molecular, and epigenetic characterization of 3 cases.

Journal of neuropathology and experimental neurology
2024

Imaging manifestations of papillary glioneuronal tumors.

Neurosurgical review
2024

Multi-pronged analysis of pediatric low-grade glioma reveals a unique tumor microenvironment associated with BRAF alterations.

bioRxiv : the preprint server for biology
2024

Infratentorial Relapsing Neuroglial Tumors in Adults: Management and Unsolved Issues-A Systematic Review.

Brain sciences
2024

Neuropathology and epilepsy surgery - 2024 update.

Free neuropathology
2024

Clinical characteristics and surgical outcomes of low-grade epilepsy-associated brain tumors.

Therapeutic advances in neurological disorders
2024

Preoperative 11 C-Methionine PET-MRI in Pediatric Infratentorial Tumors.

Clinical nuclear medicine
2024

Extremely slow-growing cerebellar ganglioglioma in an elderly patient.

Surgical neurology international
2024

Natural history and neuro-oncological approach in spinal gangliogliomas: a systematic review.

Neurosurgical review
2024

Middle temporal gyrus approach to mesial temporal lobe tumours in children.

Neurologia i neurochirurgia polska
2024

Cerebellar anaplastic ganglioglioma in a septuagenarian.

Radiology case reports
2024

Experience in treating children with ocular dyskinesia and hemifacial spasm secondary to pontine tumours adjacent to the fourth ventricle and systematic review.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
2024

Germline BRCA2 pathogenic variants in pediatric ganglioglioma: Case report and review of the literature.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
2023

Long-term epilepsy associated-tumors (LEATs): what is new?

Arquivos de neuro-psiquiatria
2024

Leat-associated seizures the possible role of EAAT2, pyruvate carboxylase and glutamine synthetase.

Epilepsy research
2023

A new subtype of diffuse midline glioma, H3 K27 and BRAF/FGFR1 co-altered: a clinico-radiological and histomolecular characterisation.

Acta neuropathologica
2024

Is intraoperative electrocorticography (ECoG) for long-term epilepsy-associated tumors (LEATs) more useful in children?-A Randomized Controlled Trial.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
2024

Ganglioglioma cells potentiate neuronal network synchronicity and elicit burst discharges via released factors.

Neurobiology of disease
2023

Adult cerebral high-grade glioneuronal tumor with perivascular or pseudopapillary growth co-existing with low-grade tumor: a case report.

International journal of clinical and experimental pathology
2023

Long term activity of vemurafenib in cancers with BRAF mutations: the ACSE basket study for advanced cancers other than BRAFV600-mutated melanoma.

ESMO open
2024

Metameric pruritus as the sole manifestation of an intramedullary tumor in a toddler.

Pediatric dermatology
2023

High-Grade Temporal Ganglioglioma in an Older Adult Woman.

Cureus
2023

Epilepsy Outcome and Pathology Analysis for Ganglioglioma: A Series of 51 Pediatric Patients.

Pediatric neurology
2024

An imaging review of the hippocampus and its common pathologies.

Journal of neuroimaging : official journal of the American Society of Neuroimaging
2023

Successful epilepsy surgery in two cases with multiple sclerosis.

Epileptic disorders : international epilepsy journal with videotape
2023

'Déjà Vu', a Mind Trick or a Warning Sign? A Case Report.

Acta medica portuguesa
2024

Nomograms Based on MRI Radiomics for Differential Diagnosis and Predicting BRAFV600E Expression in Pleomorphic Xanthoastrocytoma and Ganglioglioma.

Academic radiology
2023

Epileptic versus neuro-oncological focus of management in pediatric patients with concurrent primary brain lesion and seizures: a systematic review.

Journal of neurosurgery. Pediatrics
2023

MRI Findings of Desmoplastic Infantile Ganglioglioma: A Case Report and Analysis.

Cureus
2023

Surgical treatment of epilepsy - Initial experience from a comprehensive epilepsy program in coastal South India.

Journal of neurosciences in rural practice
2023

Comparison of Imaging Characteristics of Gangliogliomas between Child/Adolescent Group and Adult Group.

Current medical imaging
2023

Intraoperative visual evoked potential recording in occipital tumor surgery.

Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko
2024

Neuropil-like islands are a possible pathogenetic link between glioblastoma and gangliocytoma/ganglioglioma in a case of synchronous bilateral brain tumors.

Neuropathology : official journal of the Japanese Society of Neuropathology
2023

Unusual Locations of Gangliogliomas: Intraventricular and Posterior Fossa.

Turkish neurosurgery
2023

Robot-assisted transcerebellar stereotactic approach to the posterior fossa in pediatric patients: a technical note.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
2023

Long-term outcomes of symptomatic optic pathway glioma: 32-year experience at a single Western Australian tertiary pediatric oncology center.

Frontiers in oncology
2023

Vestibular seizures and spontaneous downbeat nystagmus of ganglioglioma origin: a case report.

BMC neurology
2023

Freiburg Neuropathology Case Conference : Recurrent Speech Arrest, Neologistic Jargon Aphasia, and Impaired Memory Function in a 39-year-old Patient.

Clinical neuroradiology
2023

A rare tumor in the sellar region: ganglioglioma, a case report and a general overview.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
2024

Papilledema as the Presenting Sign of Pineal Ganglioglioma.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
2024

MRI characteristics predict BRAF V600E status in gangliogliomas and pleomorphic xanthoastrocytomas and provide survival prognostication.

Acta radiologica (Stockholm, Sweden : 1987)
2023

Recurrent TRAK1::RAF1 Fusions in pediatric low-grade gliomas.

Brain pathology (Zurich, Switzerland)
2023

Laughter isn't always the best medicine, sometimes it's one of the symptoms.

Epilepsy & behavior reports
2023

A comprehensive analysis of infantile central nervous system tumors to improve distinctive criteria for infant-type hemispheric glioma versus desmoplastic infantile ganglioglioma/astrocytoma.

Brain pathology (Zurich, Switzerland)
2023

A unique case of intracranial collision tumor composed of ganglioglioma WHO gr I and supratentorial ependymoma WHO gr III: case-based literature review.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
2023

Laser interstitial thermal therapy (LITT) for pediatric patients affected by intracranial tumors.

Frontiers in neurology
2023

Intraventricular ganglioglioma: a rare case report.

Journal of surgical case reports
2023

Intraparenchymal Schwannoma of Temporal Lobe: A Case Report and Review of the Literature.

Asian journal of neurosurgery
2023

[Surgical Pathological Features of Epileptogenic Brain Lesions: Cortical Dysplasia and Tumors].

Brain and nerve = Shinkei kenkyu no shinpo
2023

Ganglioglioma arising in an ovarian teratoma.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
2023

Ganglioglioma with adverse clinical outcome and atypical histopathological features were defined by alterations in PTPN11/KRAS/NF1 and other RAS-/MAP-Kinase pathway genes.

Acta neuropathologica
2023

Ganglioglioma deep transcriptomics reveals primitive neuroectoderm neural precursor-like population.

Acta neuropathologica communications
2023

Stereo-electroencephalography (SEEG)-Guided Surgery in Epilepsy With Cingulate Gyrus Involvement: Electrode Implantation Strategies and Postoperative Seizure Outcome.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society
2023

Rapid symptomatic improvement in two patients with ganglioglioma after restarting BRAF inhibitor therapy.

Pediatric blood & cancer
2023

The clinicopathological features of ganglioglioma with CD34 expression and BRAF mutation in patients with epilepsy.

Frontiers in molecular neuroscience
2023

Primary spinal intramedullary anaplastic ganglioglioma in a pediatric patient.

Surgical neurology international
2023

DNA methylation-based classification of glioneuronal tumours synergises with histology and radiology to refine accurate molecular stratification.

Neuropathology and applied neurobiology
2023

Clinical, histological, and molecular features of gliomas in adults with neurofibromatosis type 1.

Neuro-oncology
2023

Value of quantitative apparent diffusion coefficients in differentiating low-grade gliomas from mixed neuronal-glial tumors.

World neurosurgery: X
2023

Genomic and epigenomic re-categorization of congenital glioblastoma and desmoplastic infantile ganglioglioma.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
2022

Low-grade epilepsy-associated neuroepithelial tumors: Tumor spectrum and diagnosis based on genetic alterations.

Frontiers in neuroscience
2022

Implications of BRAF V600E mutation in gliomas: Molecular considerations, prognostic value and treatment evolution.

Frontiers in oncology
2023

Clinico-pathological and epigenetic heterogeneity of diffuse gliomas with FGFR3::TACC3 fusion.

Acta neuropathologica communications
2022

Case report: BRAF-inhibitor therapy in BRAF-mutated primary CNS tumours including one case of BRAF-mutated Rosai-Dorfman disease.

Frontiers in medicine
2022

Oligodendroglioma with ganglioglioma-like maturation: the histopathological diagnostic challenge of a brain neoplasm with aberrant neuronal component - A case report and review of the literature.

Surgical neurology international
2022

Posterior Fossa Intra-Axial Lesion: There Are Pathologies Beyond Metastases.

Asian journal of neurosurgery
2022

Upfront BRAF/MEK inhibitors for treatment of high-grade glioma: A case report and review of the literature.

Neuro-oncology advances
2023

Pearls & Oy-sters: Salt and Pepper Sign, PLNTY for Drug-Resistant Epilepsy.

Neurology
2022

Pediatric Low-Grade Glioma Surgery with Sodium Fluorescein: Efficient Localization for Removal and Association with Intraoperative Pathological Sampling.

Diagnostics (Basel, Switzerland)
2022

Suprasellar Ganglioglioma Arising from the Third Ventricle Floor: A Case Report and Review of the Literature.

Tomography (Ann Arbor, Mich.)
2023

Neurochemical Profile of BRAFV600E/AktT308D/S473D Mouse Gangliogliomas Reveals Impaired GABAergic System Inhibition.

Developmental neuroscience
2022

Rare clinical manifestation of multiple endocrine neoplasia type 1.

Neuro endocrinology letters
2022

A Patient With Epilepsy, Ganglioglioma, and Oligodendroglioma With Anaplastic Foci in the Same Left Frontoparietal Lesion: A Case Report.

Cureus
2022

Improved psychotic symptoms following resection of amygdalar low-grade glioma: illustrative case.

Journal of neurosurgery. Case lessons
2022

A Rapid and Malignant Recurrence of Ganglioglioma Attribute to Neuronal Differentiation.

Neurology India
2022

High-grade desmoplastic infantile astrocytoma in a 1-year-old child with Down's syndrome: a case report.

Journal of medical case reports
2022

[The introduction of glioneuronal and neuronal tumors in 2021 WHO classification of tumors of the central nervous system (5th edition)].

Zhonghua bing li xue za zhi = Chinese journal of pathology
2022

Classification of Pediatric Gangliogliomas Based on the Histological Infiltration.

Current oncology (Toronto, Ont.)
2022

GABAA receptor function is enhanced by Interleukin-10 in human epileptogenic gangliogliomas and its effect is counteracted by Interleukin-1β.

Scientific reports
2022

First Case of a Cerebrocortical Ganglioglioma in a Dog.

Veterinary sciences
2022

Prevalence of seizures in brain tumor: A meta-analysis.

Epilepsy research
2022

Early Epilepsy Surgery in Benign Cerebral Tumors: Avoid Your 'Low-Grade' Becoming a 'Long-Term' Epilepsy-Associated Tumor.

Journal of clinical medicine
2022

NTRK3 gene fusion in an adult ganglioglioma: illustrative case.

Journal of neurosurgery. Case lessons
2022

Teratoma With Malignant Ectomesenchymoma in the Pineal Region: A Case Report.

Cureus
2022

Seizure outcomes and prognostic factors in patients with gangliogliomas associated with epilepsy.

Frontiers in surgery
2022

MR Imaging Characteristics and ADC Histogram Metrics for Differentiating Molecular Subgroups of Pediatric Low-Grade Gliomas.

AJNR. American journal of neuroradiology
2022

Anaplastic ganglioglioma-A diagnosis comprising several distinct tumour types.

Neuropathology and applied neurobiology
2022

Gliosarcoma With Glioneuronal and Rhabdomyosarcoma Components.

Cureus
2022

Treatment Limitations for Pediatric Diffuse Intrinsic Pontine Gliomas in a Middle-Income Country.

Journal of neurosciences in rural practice
2022

EANO - EURACAN - SNO Guidelines on circumscribed astrocytic gliomas, glioneuronal, and neuronal tumors.

Neuro-oncology
2022

An Endoscopic Transcortical-Transventricular Approach to Septum Pellucidum Ganglioglioma.

Neurology India
2022

Pineal region ganglioglioma: A neoplasm with a bimodal age distribution.

Surgical neurology international
Ver todos os 711 no EuropePMC

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Doenças relacionadas

Doenças com sintomas parecidos — ajudam quem ainda está buscando diagnóstico

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Use of tumor treating fields for a malignant brain tumor in a pregnant woman: Case report.
    Brain & spine· 2026· PMID 41716879mais citado
  2. SpikeSpector software for MultiElectrode Arrays: Field potential analysis and spatial integration of electrophysiological and histological data.
    Journal of neuroscience methods· 2026· PMID 41176242mais citado
  3. A 6-year-old boy with left temporal lobe mass.
    Brain pathology (Zurich, Switzerland)· 2026· PMID 41674003mais citado
  4. Multinodular and vacuolating neuronal tumor: molecular genetics and DNA methylation analysis of 12 cases.
    The Journal of pathology· 2026· PMID 41879092mais citado
  5. Endoscopic management of cranial screw migration to cerebral aqueduct causing hydrocephalus.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery· 2026· PMID 41824091mais citado
  6. Low-grade Epilepsy-associated Tumors and Other Acquired Causes of Epilepsy: MR Imaging.
    Neuroimaging Clin N Am· 2026· PMID 41932777recente
  7. [Biopsy in the treatment of children with diffuse brainstem tumors].
    Zh Vopr Neirokhir Im N N Burdenko· 2026· PMID 41930425recente
  8. Molecular features in gangliogliomas: a systematic review.
    Childs Nerv Syst· 2026· PMID 41721014recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:251949(Orphanet)
  2. MONDO:0016733(MONDO)
  3. GARD:2430(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Q460556(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Ganglioglioma
Compêndio · Raras BR

Ganglioglioma

ORPHA:251949 · MONDO:0016733
CID-10
D33.0 · Neoplasia benigna do encéfalo, supratentorial
CID-11
Ensaios
6 ativos
MedGen
UMLS
C0206716
Repurposing
1 candidato
5-aminolevulinic-acidoxidizing agent
EuropePMC
Wikidata
Papers 10a
DiscussaoAtiva

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