Stress-induced OMA1-mediated cleavage of AIFM1 suppresses cell growth by controlling mitochondrial OXPHOS activity.

Disruption of Mitophagy-Related Gene Expression in Gestational Diabetes Mellitus: A Transcriptomic and Machine Learning Approach.

Diverse mitochondrial stresses activate PINK1-PRKN/parkin mitophagy by a unified mechanism.

Mitochondrial Precursor Overaccumulation Stress.

Mitochondrial dysfunction and programmed cell death in Alzheimer's disease: A retrospective bioinformatics study.

Thiamine (Vitamin B1) metabolism in schistosomes.

Amyloid-β and Mitochondrial Membranes: A Missing Link in Alzheimer's Pathogenesis.

LYPLAL1 Rare Loss-of-Function Variants in Humans and Deletion in Human Hepatoma Cells Protect Against MASLD.

The genetic architecture of postoperative delirium after major surgery and its relationship with nonpostoperative neurocognitive conditions: A genome-wide association study.

Amyloid beta 42 disrupts cardiac function in Alzheimer's disease mice via SLC31A1 upregulation-mediated cuproptosis.

Mitofusin MFN2 acts as a molecular sensor preventing protein aggregation and mitophagy, with a protective effect against apoptosis in Charcot-Marie-Tooth type 2A disease.

ALDH2 activation protects against mutant TOMM40-mediated mitochondrial dysfunction and neurodegeneration in Alzheimer's disease.

Identification of Mitophagy-Related Genes With Diagnostic Value in Atherosclerosis Using Bioinformatics Analysis and Experiment Validation.

A dynamic displacement mechanism drives protein import into mitochondria.

ZFT is the major iron and zinc transporter in Toxoplasma gondii.

The association of Alzheimer's disease-related SNPs with mild cognitive impairment susceptibility in the Chinese population.

Immunohistochemical Analysis of Tom20 in Choroid Plexus Epithelial Cells From Elderly Brains With Neurodegenerative Diseases.

TOM70-Mitochondrial Pathway Reduction Mediates DEHP-Induced Neuroinflammation in Mice.

Interplay Between 3D Chromatin Architecture and Gene Regulation at the APOE Locus Contributes to Alzheimer's Disease Risk.

Loss of Sugen Kinase 495 in macrophages alleviates chronic colitis by improving mitochondrial stress.

The Diagnostic Reliability of BIN1 and TOMM40 Genotyping in Assessing Dementia Risk.

Growth Hormone Response in a Child With a Homozygous TOMM7 Mutation: Novel Therapeutic Insights.

Cellular proteostasis during mitochondrial protein import clogging requires the mitochondrial F-box protein 1 and DJ-1 homolog HSP31 in Saccharomyces cerevisiae.

Synuclein and Mitochondrial Dysfunction: Regulating the Protein Import Complex toward PD Treatment?

The fate of pyruvate dictates cell growth by modulating cellular redox potential.

Modulation of adipose inflammation and mitochondrial pathways by a yeast-derived β-1,3/1,6-glucan and vitamin complex: an open-label pilot study of Lalmin® immune pro in older overweight adults.

A direct role for a mitochondrial targeting sequence in signalling stress.

Stress at the gates: Mitochondrial import dysfunctions, response pathways, and therapeutic potential.

Integrated multi-omics and machine learning elucidate the pathogenic role of mitophagy in osteoarthritis and identify novel therapeutic strategies.

N-terminal α-amino SUMOylation promotes phosphorylation-independent cofilin-1 translocation to the mitochondrial matrix and induces apoptosis.

Targeting TOMM40 and TOMM22 to Rescue Statin-Impaired Mitochondrial Function, Dynamics, and Mitophagy in Skeletal Myotubes.

Secondary Mitochondrial Dysfunction in Gaucher Disease Type I, II and III-Review of the Experimental and Clinical Evidence.

The Mitochondrial F-box protein 1 and DJ-1 homolog HSP31 support cellular proteostasis during mitochondrial protein import clogging.

Mitochondrial protein TOMM7 alleviates diabetic kidney disease by regulating mitophagy via intracellular redistribution of phospholipase PLA2G6.

A unified mechanism for mitochondrial damage sensing in PINK1-Parkin-mediated mitophagy.

The dynamic lateral gate of the mitochondrial β-barrel biogenesis machinery is blocked by darobactin A.

Beyond the nucleus: the ATM-CHEK2 axis senses mtROS to orchestrate mitophagy.

Mitochondrial Transfer Rescues Respiration to Support De Novo Pyrimidine Biosynthesis and Tumor Progression.

Baicalin inhibits infectious bronchitis virus replication via MAVS-dependent interferon-β upregulation and mitochondrial function preservation.

PEDV NSP8 inhibits IFN-III production induced by MAVS through downregulation of PEX13.

Leucine inhibits degradation of outer mitochondrial membrane proteins to adapt mitochondrial respiration.

Substrate recognition by the human mitochondrial processing peptidase and its processing of PINK1.

Jiao-tai-wan and its component coptisine attenuate PCOS by regulating mitochondrial cholesterol import through suppression of SIRT1 ubiquitination.

Tuning the Hsp70 chaperone cycle: emerging roles of GrpE-like nucleotide exchange factors in proteostasis and organelle function.

TbTim20 facilitates protein import at a low membrane potential in trypanosomes lacking the mitochondrial genome.

From Biogenesis to Breakdown: How Protein Biogenesis and Quality Control Failures Drive Mitochondrial Disease.

Down-regulation of HSPA9 reduces tyrosine hydroxylase-positive neurons in mouse substantia nigra and induces Parkinson's disease-like motor impairments.

Elevated co-expression of TIMM17A and NMT1 is associated with poor survival in non-small cell lung cancer.

DDHD2 provides a flux of saturated fatty acids for neuronal energy and function.

Tom70 prevents fibrotic activation of aortic valve interstitial cells via EPA-activated Autophagic flux.

Repeat Variants, Biomarkers, and Molecular Signatures in Parkinson's Disease: ATXN2, ATXN3, CACNA1A, PRNP, TBP, C9ORF72, TOMM40, APOE, and POLG-A Swedish Perspective.

Mitochondria-Localized Nestin Protects Mesenchymal Stem Cells from Senescence by Maintaining Cristae Structure and Function.

Toxic Tango in Parkinson's Disease: A dance between αSyn and iron import, export and speciation.

Mtx2 requirement for craniofacial morphogenesis with implications for mandibuloacral dysplasia.

Could R-Ketamine and Wolfram Syndrome Inform Understanding of Depression and Suicidality? A Sigma-1 Receptor-Based Perspective.

TIMM8A-TIMM13 Complex Exerts Oncogenic Functions in Lung Cancer.

Mitochondrial protein import stress augments α-synuclein aggregation and neural damage independent of bioenergetics.

A Pathogenic L2HGDH Variant Impairs Mitochondrial Targeting and Enzyme Function in L-2-Hydroxyglutaric Aciduria: Clinical and Functional Evidence from Two Affected Siblings.

Systemic Neurodegeneration and Brain Aging: Multi-Omics Disintegration, Proteostatic Collapse, and Network Failure Across the CNS.

Jolkinolide B Activates Mitophagy to Exhibit Antipancreatic Cancer Activity and Alleviate Cognitive Deficits in Alzheimer's Disease.

Quality control at the powerhouse: mitochondrial proteostasis dysfunction and disease.

Epigenetic regulation of the respiratory chain by a mitochondrial distress-related redox signal.

Unraveling the power of TOMM40: Driving PHB1-mediated mtDNA release and mitophagy to fuel breast cancer progression.

ROS-dependent localization of glycolytic enzymes to mitochondria.

Genotyping TOMM40'523 poly-T polymorphisms using whole-genome sequencing.

SENP6 Maintains Mitochondrial Homeostasis by Regulating Mitochondrial Protein Import Through deSUMOylation of TOM40.

SLC39A13 Regulates Heart Function via Mitochondrial Iron Homeostasis Maintenance.

AHSA1/Hsp90α Complex Facilitates Microglial Mitophagy by Targeting TOMM70 in Parkinson Disease.

Stressful situations: Molecular insights on mitochondrial quality control pathways.

Organic cation transporter 3 on neuronal mitochondria mediates MPP+-induced mitochondrial dysfunction and neurotoxicity in a TIMM22-dependent manner.

MitoRUSH as a tool to study the efficiency of mitochondrial import in complex I-deficient cells.

SLC25A42-Related Mitochondrial Disorder: New Cases and Literature Review.

TIMM8B promotes oxidative phosphorylation and glycolysis by inhibiting the mtROS/ASK1/JNK signaling pathway in ovarian cancer.

A novel TIMM8A mutation in Mohr-Tranebjaerg syndrome without hearing loss and with basal ganglia iron deposition.

Mitochondrial protein nmd regulates lipophagy and general autophagy during development.

Endothelial soluble epoxide hydrolase links polyunsaturated fatty acid metabolism to oxidative stress and atherosclerosis progression.

Integrative Proteome and Transcriptome Analyses Reveal the Metabolic Disturbance of the Articular Cartilage in Kashin-Beck Disease, an Endemic Arthritis.

Rescue of the First Mitochondrial Membrane Carrier, the mPiC, by TAT-Mediated Protein Replacement Treatment.

Sex-specific loss of mitochondrial membrane integrity in the auditory brainstem of a mouse model of Fragile X Syndrome.

Quality control of un-imported mitochondrial proteins at a glance.

Physical Resilience May Offset Mortality Risks Associated With Genetic Predisposition to Shorter Survival: A Population-based Cohort Study.

Impact of pathogenic mutations on the refolding ability and stability of human mitochondrial Phenylalanyl-tRNA synthetase.

Mitochondrial quality control and stress signaling pathways in the pathophysiology of cardio-renal diseases.

USP30 Aggravating the Malignant Progression of Breast Cancer and Its Resistance to Tamoxifen by Inhibiting the Ubiquitination of TOMM40.

SARS-CoV-2 Membrane Protein Induces MARCHF1/GPX4-Mediated Ferroptosis by Promoting Lipid Accumulation.

Using multiple modalities to confirm diagnosis in patients with suspected peroxisome biogenesis disorders.

Structure of human PINK1 at a mitochondrial TOM-VDAC array.

CHCHD2 rescues the mitochondrial dysfunction in iPSC-derived neurons from patient with Mohr-Tranebjaerg syndrome.

Novel subcellular regulatory mechanisms of protein homeostasis and its implications in amyotrophic lateral sclerosis.

A mitochondrial outer membrane protein TOMM20 maintains protein stability of androgen receptor and regulates AR transcriptional activity in prostate cancer cells.

The role of l-serine and l-threonine in the energy metabolism and nutritional stress response of Trypanosoma cruzi.

Sengers syndrome caused by biallelic TIMM29 variants and RNAi silencing in Drosophila orthologue recapitulates the human phenotype.

A long-lived pool of PINK1 imparts a molecular memory of depolarization-induced activity.

Structural insights into human PNPase in health and disease.

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis.

Mitofusin 2 displays fusion-independent roles in proteostasis surveillance.

Development and validation of a sensitive sandwich ELISA against human PINK1.

MIA40 circumvents the folding constraints imposed by TRIAP1 function.

Modelling Peroxisomal Disorders in Zebrafish.

Novel c.221+1dup pathogenic variant in AGK gene linked to Sengers syndrome.

TREM1 interferes with macrophage mitophagy via the E2F1-mediated TOMM40 transcription axis in rheumatoid arthritis.

Regulation of Mutant Huntingtin Mitochondrial Toxicity by Phosphomimetic Mutations within Its N-Terminal Region.

Mitochondrial YME1L1 governs unoccupied protein translocase channels.

Thirty years of StAR gazing. Expanding the universe of the steroidogenic acute regulatory protein.

Hotspots for Disease-Causing Mutations in the Mitochondrial TIM23 Import Complex.

Aberrant activation of adenine nucleotide translocase 3 promotes progression and chemoresistance in multiple myeloma dependent on PINK1 transport.

Association of APOE alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease neuroimaging markers.

Mitochondrial quality control: the real dawn of intervertebral disc degeneration?

Subcellular NAD+ pools are interconnected and buffered by mitochondrial NAD.

Mitochondria-targeted oligomeric α-synuclein induces TOM40 degradation and mitochondrial dysfunction in Parkinson's disease and parkinsonism-dementia of Guam.

Biochemical and neurophysiological effects of deficiency of the mitochondrial import protein TIMM50.

GRIM-19-mediated induction of mitochondrial STAT3 alleviates systemic sclerosis by inhibiting fibrosis and Th2/Th17 cells.

Shared Genetic Links Between Nonalcoholic Fatty Liver Disease and Coronary Artery Disease.

Homozygous variant in translocase of outer mitochondrial membrane 7 leads to metabolic reprogramming and microcephalic osteodysplastic dwarfism with moyamoya disease.

Heterozygous de novo variants in HSPD1 cause hypomyelinating leukodystrophy through impaired HSP60 oligomerisation.

Analysis of mitochondrial biogenesis regulation by oxidative stress.

Analysis of targeting signals for mitochondrial intermembrane space import.

Monitoring mitochondrial precursor processing and presequence peptide degradation.

Transgelin 2 guards T cell lipid metabolism and antitumour function.

Association of common and rare variants with Alzheimer's disease in more than 13,000 diverse individuals with whole-genome sequencing from the Alzheimer's Disease Sequencing Project.

Distinct roles for the domains of the mitochondrial aspartate/glutamate carrier citrin in organellar localization and substrate transport.

Identification of Haemoproteus infection in an imported grey crowned crane (Balearica regulorum) in China.

The role of PINK1-Parkin in mitochondrial quality control.

QSOX2 Deficiency-induced short stature, gastrointestinal dysmotility and immune dysfunction.

Bi-Allelic Splicing Variant, c.153-2A > C in TOMM7 Is Associated With Leigh Syndrome.

Translation stalling induced mitochondrial entrapment of ribosomal quality control related proteins offers cancer cell vulnerability.

Quantitative proteomics of patient fibroblasts reveal biomarkers and diagnostic signatures of mitochondrial disease.

Role of TOMM34 on NF-κB activation-related hyperinflammation in severely ill patients with COVID-19 and influenza.

Investigation in yeast of novel variants in mitochondrial aminoacyl-tRNA synthetases WARS2, NARS2, and RARS2 genes associated with mitochondrial diseases.

Nucleoporin 153 deficiency in adult neural stem cells defines a pathological protein-network signature and defective neurogenesis in a mouse model of AD.

Amyotrophic Lateral Sclerosis and swim training affect copper metabolism in skeletal muscle in a mouse model of disease.

Identification of Autophagy-Related Biomarkers and Diagnostic Model in Alzheimer's Disease.

Unfolded proteins in the mitochondria activate HRI and inhibit mitochondrial protein translation.

Mitochondrial-derived compartments remove surplus proteins from the outer mitochondrial membrane.

Omnibus proteome-wide association study identifies 43 risk genes for Alzheimer disease dementia.

Translocase of Outer Mitochondrial Membrane 40, as a Promising Biomarker for the Diagnosis of Polycystic Ovary Syndrome and Pan-Cancer.

Spautin-1 promotes PINK1-PRKN-dependent mitophagy and improves associative learning capability in an alzheimer disease animal model.

Human fascioliasis emergence in southern Asia: Complete nuclear rDNA spacer and mtDNA gene sequences prove Indian patient infection related to fluke hybridization in northeastern India and Bangladesh.

Metabolic gene function discovery platform GeneMAP identifies SLC25A48 as necessary for mitochondrial choline import.

Asymmetric apical domain states of mitochondrial Hsp60 coordinate substrate engagement and chaperonin assembly.

N-Myristoytransferase Inhibition Causes Mitochondrial Iron Overload and Parthanatos in TIM17A-Dependent Aggressive Lung Carcinoma.

Low-Iron Diet-Induced Fatty Liver Development Is Microbiota Dependent and Exacerbated by Loss of the Mitochondrial Iron Importer Mitoferrin2.

Clinical spectrum of human STAR variants and their genotype-phenotype correlation.

Enhancing mitochondrial proteolysis alleviates alpha-synuclein-mediated cellular toxicity.

Activation of the integrated stress response in human hair follicles.

Mitochondrial membrane synthesis, remodelling and cellular trafficking.

Molecular pathways in mitochondrial disorders due to a defective mitochondrial protein synthesis.

Mitochondrial endogenous substance transport-inspired nanomaterials for mitochondria-targeted gene delivery.

Mechanism of human PINK1 activation at the TOM complex in a reconstituted system.

Redox regulation of UPR signalling and mitochondrial ER contact sites.

Reduced Protein Import via TIM23 SORT Drives Disease Pathology in TIMM50-Associated Mitochondrial Disease.

Targeting KPNB1 with genkwadaphnin suppresses gastric cancer progression through the Nur77-mediated signaling pathway.

SLC7A11-mediated cystine import protects against NDUFS7 deficiency-induced cell death in HEK293T cells.

Cystine/glutamate antiporter xCT controls skeletal muscle glutathione redox, bioenergetics and differentiation.

Long-read sequencing for 29 immune cell subsets reveals disease-linked isoforms.

TOM5 regulates the mitochondrial membrane potential of alveolar epithelial cells in organizing pneumonia.

Molecular Characterization and Inhibition of a Novel Stress-Induced Mitochondrial Protecting Role for Misfolded TrkAIII in Human SH-SY5Y Neuroblastoma Cells.

Export of heme by the feline leukemia virus C receptor regulates mitochondrial biogenesis and redox balance in the hematophagous insect Rhodnius prolixus.

Mitochondrial Chaperone Code: Just warming up.

Defective ferritinophagy and imbalanced iron metabolism in PBDE-47-triggered neuronal ferroptosis and salvage by Canolol.

Mitochondrial dynamics: updates and perspectives.

[Genetic basis of postoperative cognitive dysfunction].

A new type of blood-brain barrier aminoacidopathy underlies metabolic microcephaly associated with SLC1A4 mutations.

Mitochondrial phosphate-carrier deficiency mimicking infantile-onset Pompe disease.

Intermembrane space-localized TbTim15 is an essential subunit of the single mitochondrial inner membrane protein translocase of trypanosomes.

Allopregnanolone and its antagonist modulate neuroinflammation and neurological impairment.

Mitochondrial import stress and PINK1-mediated mitophagy: the role of the PINK1-TOMM-TIMM23 supercomplex.

Exploring Genetic Associations of 3 Types of Risk Factors With Ischemic Stroke: An Integrated Bioinformatics Study.

On the effect heterogeneity of established disease susceptibility loci for Alzheimer's disease across different genetic ancestries.

Cytosolic retention of HtrA2 during mitochondrial protein import stress triggers the DELE1-HRI pathway.

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis.

Localization of RNAs to the mitochondria-mechanisms and functions.

Identification of a novel MT-ND3 variant and restoring mitochondrial function by allotopic expression of MT-ND3 gene.

Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress.

SLC25A51 decouples the mitochondrial NAD+/NADH ratio to control proliferation of AML cells.

Rescue of mitochondrial import failure by intercellular organellar transfer.

TIM22 and TIM29 inhibit HBV replication by up-regulating SRSF1 expression.

New insights into the role of mitochondrial metabolic dysregulation and immune infiltration in septic cardiomyopathy by integrated bioinformatics analysis and experimental validation.

The Role of Chorein Deficiency in Late Spermatogenesis.

Reprimo (RPRM) mediates neuronal ferroptosis via CREB-Nrf2/SCD1 pathways in radiation-induced brain injury.

PMPCA-Related Encephalopathy: Novel Variants, Phenotype Extension, and Mitochondrial Morphology.

TOMM40 Correlates with Cholesterol and is Predictive of a Favorable Prognosis in Endometrial Carcinoma.

APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease.

Distinct structural motifs are necessary for targeting and import of Tim17 in Trypanosoma brucei mitochondrion.

CRISPR/Cas9-mediated base editors and their prospects for mitochondrial genome engineering.

Amyotrophic lateral sclerosis associated disturbance of iron metabolism is blunted by swim training-role of AKT signaling pathway.

Transgelin 2 guards T cell lipid metabolic programming and anti-tumor function.

Neuroprotective Mushrooms.

AGO2 Protects Against Diabetic Cardiomyopathy by Activating Mitochondrial Gene Translation.

One advantageous reflection of iron metabolism in context of normal physiology and pathological phases.

Mfsd7b facilitates choline transport and missense mutations affect choline transport function.

Classifying Alzheimer's disease and normal subjects using machine learning techniques and genetic-environmental features.

NADH improves AIF dimerization and inhibits apoptosis in iPSCs-derived neurons from patients with auditory neuropathy spectrum disorder.

Decoding mitochondrial-nuclear (epi)genome interactions: the emerging role of ncRNAs.

Interactions of amyloidogenic proteins with mitochondrial protein import machinery in aging-related neurodegenerative diseases.

Mechanisms of stress management in mitochondrial protein import.

LPGAT1 controls MEGDEL syndrome by coupling phosphatidylglycerol remodeling with mitochondrial transport.

Mitochondrial Translocase TOMM22 Is Overexpressed in Pancreatic Cancer and Promotes Aggressive Growth by Modulating Mitochondrial Protein Import and Function.

Genotypic Effects of the TOMM40'523 Variant and APOE on Longitudinal Cognitive Change over 4 Years: The TOMMORROW Study.