Raras
Buscar doenças, sintomas, genes...
Paraplegia espástica hereditária pura ou complexa
Mantido por Agente Raras·Colaborar como especialista →

Introdução

O que você precisa saber de cara

📋

A paraplegia espástica hereditária (PEH) é um grupo de doenças hereditárias cuja principal característica é um distúrbio progressivo da marcha. A doença apresenta rigidez progressiva (espasticidade) e contratura nos membros inferiores. A PEH também é conhecida como paraparesia espástica hereditária, paraplegia espástica familiar, doença do assentamento francês, doença de Strumpell, ou doença de Strumpell-Lorrain. Os sintomas são resultado da disfunção de longos axônios na medula espinhal. As células afetadas são os neurônios motores primários; portanto, a doença é uma doença do neurônio motor superior. A PEH não é uma forma de paralisia cerebral, embora fisicamente possa parecer e se comportar de forma muito semelhante à diplegia espástica.

🏥
SUS: Sem cobertura SUSScore: 0%
Você se identifica com essa condição?
O Raras está aqui pra te apoiar — com ou sem diagnóstico

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Entender a doença

Do básico ao detalhe, leia no seu ritmo

Preparando trilha educativa...

Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1
Últimos 10 anos200publicações
Pico2026196 papers
Linha do tempo
2025Hoje · 2026
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Paraplegia espástica hereditária pura ou complexa

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

Pesquisa e ensaios clínicos

Nenhum ensaio clínico registrado para esta condição.

🧪 Está conduzindo uma pesquisa?
Divulgue para pacientes e familiares que acompanham esta doença.
Divulgar pesquisa →

Publicações mais relevantes

Timeline de publicações
0 papers (10 anos)
#1

Copper-hydroxyl interactions drive water-promoted copper surface oxidation and mobility.

Nature communications2026 Mar 24

Este estudo revelou que a presença de água, especificamente seus grupos hidroxila, acelera significativamente a oxidação do cobre e aumenta a mobilidade de seus átomos na superfície, ao desorganizar a camada de cobre e facilitar a penetração do oxigênio. Para pacientes e médicos, essa descoberta é crucial para o desenvolvimento de implantes e dispositivos médicos que utilizam cobre ou suas ligas. Compreender esse mecanismo permite criar materiais mais resistentes à corrosão em ambientes úmidos do corpo, garantindo maior durabilidade e segurança.

🇧🇷 traduzido
#2

Pre-monsoon aerosol intensification and enhanced atmospheric warming over the South-Eastern Arabian Sea.

Environmental science and pollution research international2026 Mar 23

O título que você forneceu ("Pure or complex hereditary spastic paraplegia") não corresponde ao resumo do artigo científico que você anexou, que é sobre "Pre-monsoon aerosol intensification and enhanced atmospheric warming over the South-Eastern Arabian Sea". Considerando o *conteúdo do artigo que você forneceu* (sobre aerossóis e aquecimento atmosférico), e focando no que *poderia ser indiretamente relevante para saúde pública* (embora o artigo não discuta implicações médicas diretas para pacientes ou médicos clínicos): O artigo descreve uma intensa acumulação de aerossóis (principalmente poeira poluída e fumaça de regiões industriais e de queima de biomassa) no sudeste do Mar Arábico durante a pré-monção. Esses aerossóis, que se elevam na atmosfera, são altamente absorventes e causam um aumento significativo (de 4 a 6 para 8-12 W m⁻²) do forçamento radiativo atmosférico. Isso resulta num aquecimento da baixa atmosfera de cerca de 1-2°K, o que pode modificar a estrutura térmica atmosférica e ter prováveis implicações nas interações aerossol-nuvem-precipitação e nos padrões climáticos regionais da costa oeste da Índia. **Para pacientes e médicos, o que é mais relevante é que este estudo foca em fenômenos atmosféricos e climáticos. Embora a poluição do ar e as mudanças climáticas tenham impactos na saúde humana (doenças respiratórias, cardiovasculares, estresse térmico, etc.), este artigo específico se limita à descrição dos processos físicos atmosféricos e não detalha as consequências diretas para a saúde ou intervenções médicas.**

🇧🇷 traduzido
#3

Impact of cardiometabolic criteria on the pathogenesis of MASLD and diagnostic performance of non-invasive tests.

Journal of gastroenterology2026 Mar 23

Este estudo sobre a Doença Hepática Gordurosa Associada à Disfunção Metabólica (MASLD) revela que pacientes masculinos com hipertensão, ou aqueles com três ou mais critérios cardiometabólicos positivos, enfrentam um risco significativamente maior de desenvolver fibrose hepática avançada ou MASH (esteato-hepatite metabólica) em estágio de risco. Para médicos e pacientes, o teste não invasivo ELF (Enhanced Liver Fibrosis) provou ser uma ferramenta diagnóstica superior para detectar a progressão da fibrose avançada, funcionando bem independentemente dos fatores individuais ou do número de critérios cardiometabólicos do paciente, e superando outros testes como FIB-4 e NFS.

🇧🇷 traduzido
#4

Synthesis of gold nanorod@Pd(Pt)-Cu2O dendritic nanocomposites for plasmon-enhanced photocatalysis.

Journal of colloid and interface science2026 Mar 19

O título do artigo ("Pure or complex hereditary spastic paraplegia") não corresponde ao resumo fornecido, que descreve uma pesquisa em química de materiais. O resumo detalha a síntese de novos nanocompósitos (AuNR@Pd(Pt)-Cu2O) para otimizar a fotocatálise, mostrando que, sob luz, o AuNR@Pt-Cu2O aumentou a eficiência catalítica em mais de 35 vezes para a degradação de substâncias. Esta pesquisa foca em avanços para aplicações energéticas e ambientais, e **não possui relevância direta para pacientes ou médicos** em relação a condições de saúde humana.

🇧🇷 traduzido
#5

Thermo-Transitioning Core-Shell Microgels Combine Cohesive Reinforcement and Noncohesive Reconfigurability to Enable 3D Bioprinting and Stabilize Tissues During Incubation.

ACS biomaterials science & engineering2026 Mar 21

Este artigo descreve um novo sistema de microgéis, feito de um núcleo de PEG e uma camada de PNIPAM, projetado para aprimorar a bioimpressão 3D de tecidos. Ele permite a fabricação de estruturas celulares complexas com alta precisão à temperatura ambiente e, em seguida, oferece estabilidade estrutural e mantém a viabilidade celular durante o cultivo a 37°C. Para pacientes e médicos, essa tecnologia representa um avanço promissor na engenharia de tecidos, podendo acelerar o desenvolvimento de órgãos e tecidos substitutos mais estáveis e funcionais, além de plataformas mais eficazes para pesquisa e testes de medicamentos.

🇧🇷 traduzido

Publicações recentes

📚 EuropePMC2 artigos no totalmostrando 198

2026

Effect of nano-cerium dioxide addition in lubricating oil on particle size distribution of micro/nano-sized particulate matter in diesel engines.

Nanotechnology
2026

Understanding and Managing Ménière's Disease: A Comprehensive Case Report.

Cureus
2026

Primary pure small cell neuroendocrine carcinoma of the endometrium: a case report.

Journal of medical case reports
2026

Nitrogen Doping at the Periphery of a Quadruply-Fused Porphyrin and Its Multi-Step Proton-Coupled Electron Transfer to Form a 34π Aromatic Molecule.

Journal of the American Chemical Society
2026

Labyrinthine Abnormalities on MRI in Untreated Otosclerosis: Prevalence and Clinical Relevance.

The Laryngoscope
2026

Copper-hydroxyl interactions drive water-promoted copper surface oxidation and mobility.

Nature communications
2026

In Situ Electrochemical Construction of CoCu2O Nanoclusters for Efficient Nitrate-to-Ammonia Electroreduction.

ACS nano
2026

Biodegradability and cost comparison of polyhydroxyalkanoates-based composites with industrial waste and by-products under mesophilic anaerobic digestion.

Bioresource technology
2026

Associations between hearing, subjective memory complaints, and dementia risk factors among audiology clients.

International journal of audiology
2026

Sentinel Lymph Node Biopsy for Desmoplastic Melanoma: A Systematic Review and Meta-analysis.

Annals of surgical oncology
2026

Pre-monsoon aerosol intensification and enhanced atmospheric warming over the South-Eastern Arabian Sea.

Environmental science and pollution research international
2026

Hanseniaspora uvarum and Hanseniaspora opuntiae differ in their growth and in the production of volatile organic compounds in wine.

Applied microbiology and biotechnology
2026

Impact of cardiometabolic criteria on the pathogenesis of MASLD and diagnostic performance of non-invasive tests.

Journal of gastroenterology
2026

HipE Study-Hip Embolization for Pain Control in Hip Osteoarthritis and Greater Trochanteric Pain Syndrome: 12 Months Follow-Up.

Cardiovascular and interventional radiology
2026

Cobalt-Doped Biphasic Calcium Phosphate Orchestrates Osteogenesis-Angiogenesis Signals via Hypoxia-Mimetic Signaling.

Journal of biomedical materials research. Part A
2026

CeO2@CuxOS Photocatalyst for Diabetic Wound Healing via Programmable ROS Regulation.

ACS applied materials & interfaces
2026

Smartphone-Based Hearing Testing Versus Clinical Audiometry: A Comparative Study in Ear, Nose, and Throat Practice.

Otolaryngologia polska = The Polish otolaryngology
2026

Fabrication and sensing performance of a highly sensitive room-temperature NO₂ gas sensor based on few-layer Ti₃C₂ MXene/WO₃ nanoparticle composites.

Nanotechnology
2026

Synthesis and Properties of Boron Fluoride Complexes Using 2-(N-Pyridylamino)-1-azaazulene derivatives.

The Journal of organic chemistry
2026

Peripheral Nerve Ultrasound Findings in Leprosy: A Scoping Review of Echogenicity, Cross-Sectional Area, and Vascularization Across 15 Studies.

Clinical, cosmetic and investigational dermatology
2026

The Dual-Faceted Role of Metal-Based Nanomaterials in Hepatic Fibrosis Therapy.

International journal of nanomedicine
2026

Performance Assessment of μTASWako i50, a New Microfluidic Immunoassay System for Hepatocellular Carcinoma Biomarkers AFP, AFP-L3%, and PIVKA-II.

Cureus
2026

Development and biomechanical validation of a whole spine-thorax finite element model for quantitative biomechanical analysis.

PeerJ
2026

Ultra-sensitive IDE-based ammonia sensor fabricated using green synthesized graphene nanoplatelets and a TiO2 based composite.

RSC advances
2026

Luminescent, and thermometric properties of Er3+-activated NaCaGd(WO4)3 phosphor for solid-state lighting and thermal sensing.

RSC advances
2026

Immunomodulatory effects of biodegradable Mg-Cu-Zn alloy in esophageal cancer.

Bioactive materials
2026

Bioabsorbable Magnesium Metal Scaffolds Improve Dermal Wound Healing and Tissue Regeneration.

bioRxiv : the preprint server for biology
2026

Microfibrillated Cellulose Embedded with KCl as a Solid-Dopant Matrix into an Electrolyte-Gated Transistor.

ACS omega
2026

Copper Oxide-Based Schottky Diode Using Poly(3-hexylthiophene) as an Interlayer.

ACS omega
2026

Chelating-Assisted Green Synthesis of TiO2 Nanoparticles from Mangosteen Pericarp for Defect Control and DSSC Performance.

ACS omega
2026

Foreign Body-Associated Eikenella corrodens Aspiration Pneumonia in an Elderly Immunocompetent Adult: A Case Report.

International medical case reports journal
2026

Assessing the Feasibility of Bioscrubbing for Flue Gas Treatment and Sulfur Recovery: A Comparative Study Using Mathematical Modeling, Life Cycle Analysis, and Life Cycle Costing.

ACS environmental Au
2026

Impact of Frequency Reallocation on Cochlear Implant OutcomesRole of frequency reallocation on cochlear implant patient outcomes.

Acta oto-laryngologica
2026

Emerging p-Block Metal-Based Electrocatalysts for Energy Conversion.

Small (Weinheim an der Bergstrasse, Germany)
2026

Prognostic impact of preoperative MRI on core decompression in ARCO stage III osteonecrosis of the femoral head: a retrospective cohort study.

Journal of orthopaedic surgery and research
2026

Synthesis of gold nanorod@Pd(Pt)-Cu2O dendritic nanocomposites for plasmon-enhanced photocatalysis.

Journal of colloid and interface science
2026

Dynamic shifts in crystal methamphetamine and heroin price and purity in metropolitan Melbourne and rural Victoria, Australia, 2009-2020.

The International journal on drug policy
2026

Enhancement of macadamia protein solubility and functionality using combined pH-shift-heat treatment: Role of ionic environment (PBS vs water).

Food chemistry
2026

Overall survival from the open-label phase II trial of palbociclib in patients with advanced well-differentiated/dedifferentiated liposarcoma.

ESMO open
2026

Destruction and removal of nitrogen trifluoride (NF3), sulfur hexafluoride (SF6), and tetrafluoromethane (CF4) via three-stage molten-metal bubble column reactors.

Journal of hazardous materials
2026

Thermo-Transitioning Core-Shell Microgels Combine Cohesive Reinforcement and Noncohesive Reconfigurability to Enable 3D Bioprinting and Stabilize Tissues During Incubation.

ACS biomaterials science & engineering
2026

Cellulosic L-Lactic Acid Production by Engineered Na+-Tolerant Pediococcus acidilactici and Bipolar Membrane Electrodialysis Purification for L-Lactide Synthesis.

Biotechnology and bioengineering
2026

Lessons Learned in Orbitrap MS-Based Isotope Ratio Analysis of Organic Acid Mixtures.

Analytical chemistry
2026

Spatial identification of areas suitable for other effective area-based conservation measures in the European Union.

Conservation biology : the journal of the Society for Conservation Biology
2026

Extended high-frequency audiometry in older adults: hearing thresholds.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
2026

Photothermal solar assisted Madhuca diethyl ether fuel processing for LHR engines with AI-based performance and yield prediction.

Scientific reports
2026

Characterization of wheat bran protein/chitosan composite film: Study on the film-forming ability and bioactivities.

International journal of biological macromolecules
2026

LC-MS/MS analysis of polar pesticides in mango: enantiomers, docking, and retention mechanisms.

Food chemistry
2026

Evaluating ecological concrete cubes with recycled oyster shell aggregates for oyster reef restoration.

Marine environmental research
2026

Power and Limitations of Distributed Quantum State Purification.

Physical review letters
2026

Turbulent Dynamos in a Collapsing Cloud.

Physical review letters
2026

A unified ab initio theory of spin-phonon relaxation and decoherence uncovers fast dephasing in magnetic molecules.

Science advances
2026

Effects of confining pressure and loading direction on the mechanical behavior of schist with high content and aggregation degree of mica.

PloS one
2026

Impact of contralateral sensorineural hearing loss on prognosis in idiopathic sudden sensorineural hearing loss.

PloS one
2026

Fluoride-free synthesis of large-pore ITQ-27 aluminosilicate zeolite with a tunable composition and enhanced methanol-to-propylene performance.

Chemical communications (Cambridge, England)
2026

Mechanically Enhanced, Antibacterial, and Double-Network Hydrogel Flexible Sensors for Sleep Apnea Monitoring.

Small (Weinheim an der Bergstrasse, Germany)
2026

Correlation functions in heterodyne optical fiber dynamic light scattering: A laser velocimetry method for tracking active matter at the nanoscale.

The Journal of chemical physics
2026

Dynamics of plasma anti-Müllerian hormone concentrations before and after ovum pick-up in pure and crossbred Hokkaido native ponies.

Journal of equine science
2026

Fungi associated with seagrass Enhalus acoroides in Puttalam Lagoon, Sri Lanka: Discovery of two new species (Neodevriesia zeylanica and Neooccultibambusa zeylanica (Dothideomycetes)) and taxonomic validation of Halophilomyces (Sordariomycetes).

MycoKeys
2026

Dorsal Hand Reconstruction With Large Superficial Circumflex Iliac Artery Pure Skin Perforator Flap Without High-frequency Doppler Ultrasound.

Plastic and reconstructive surgery. Global open
2026

Ictal fear of death with preserved context dependent speech and postictal amnesia in focal epilepsy.

Frontiers in neurology
2026

Motivations, willingness, and gains: a qualitative study of experiences of helping behaviors among community-dwelling older adults in China using self-construal theory.

Frontiers in public health
2026

Efficacy and safety of transcatheter aortic valve replacement for the treatment of pure severe native aortic valve regurgitation: a single-arm meta-analysis.

Frontiers in medicine
2026

Green RP-HPLC method for the simultaneous determination of octenidine and phenoxyethanol in antiseptic formulations: integration of a lean six sigma approach.

RSC advances
2026

Active Learning-Guided Polymorph Control in Co-Precipitation Synthesis.

Small methods
2026

Upper bound on locally extractable energy from entangled pure state under feedback control.

Physical review. E
2026

Parrondo-like evolutionary advantage from stochastic switching between specialist and generalist strategies in fluctuating environments.

Physical review. E
2026

Modulational instability and charge localization in the Holstein-SSH model of DNA with mass impurities.

Physical review. E
2026

Rayleigh-Taylor instability in size-bidisperse isodense granular flow down an incline.

Physical review. E
2026

Cluster percolation in the three-dimensional ±J random-bond Ising model.

Physical review. E
2026

Two decades (2005 to 2025) of avian influenza research trends, knowledge gaps and distribution of emerging H5N1 2.3.4.4b clade in South Asia.

One health outlook
2026

Multiscale phase nucleation driven by photoinduced polarons in a volume-changing material.

Nature materials
2026

4polar3D single molecule imaging of 3D orientation in dense actin networks using ratiometric polarization splitting.

Nature communications
2026

Validation of Non-Soundproof Tablet Audiometry in Pediatrics: Comparison With Traditional Audiometry.

The Laryngoscope
2026

Decoding enhanced oily wastewater purification and photocatalytic self-cleaning performance of magnetic field-strategized composite membranes with surface-localized CoFe2O4@PDA.

Journal of hazardous materials
2026

Radiocarbon-based direct liquid scintillation counting method to quantify biogenic carbon and fossil-derived synthetic adulterants in commercial essential oils.

Talanta
2026

Synergistic Zn vacancies and Ohmic junction in zinc metal-organic framework derived nanosheet photocatalysts for enhanced CO2 photoreduction.

Journal of colloid and interface science
2026

Computational study of the mass transfer effects in metal-organic framework columns for liquid chromatography.

Journal of chromatography. A
2026

Evaluation of the Quality and Reliability of YouTube Videos as a Source of Information on Portable HBOT in Home Health Care Services Quality and Reliability Analysis of YouTube Videos on Portable HBOT.

Journal of evaluation in clinical practice
2026

From Hearing Patterns to Functional Outcomes: Quantifying Audiometric Profiles for Precision Hearing Care.

Audiology & neuro-otology
2026

Underdetermined Blind Source Separation via Weighted Simplex Shrinkage Regularization and Quantum Deep Image Prior.

IEEE transactions on image processing : a publication of the IEEE Signal Processing Society
2026

Zinc-L-carnosine mouthwash in oral mucositis patients: a single-blind, randomized, controlled trial.

Minerva dental and oral science
2026

Exploration of network-based, machine learning, MD simulations, and MM/GBSA approaches revealed luteolin from Gynura procumbens as key inhibitor of MMP9 in NSCLC.

Naunyn-Schmiedeberg's archives of pharmacology
2026

The Kantian background of Uexküll's notions of time and space.

History and philosophy of the life sciences
2026

Modulating Carrier Transport Properties at the In2O3/ZnCo2O4 Heterojunction Interface for Triethylamine Gas Sensing.

Langmuir : the ACS journal of surfaces and colloids
2026

Neural correlates of pure apathy in multiple sclerosis: An exploratory neuroimaging study.

Journal of neuropsychology
2026

Development of a High-Sensitivity Electrochemical Immunoassay Using a Fully 3D-Printed Electrocatalytic Microelectrode Probe Platform.

Analytical chemistry
2026

A Comprehensive Analysis of Metrological Traceability Tools for Urine Albumin Measurements.

Clinical chemistry
2026

Comparing undesirable behaviours between 'designer' Poodle-cross dogs and their purebred progenitor breeds.

PloS one
2026

MoS2-Based Electrocatalysts Across Major Water-Related Energy Reactions: Advances, Challenges, and Future Prospects.

ChemSusChem
2026

Interlayer Hydrogen-Hydrogen Spacing Regulates the Formation of Molecular Hydrogen in Hydrogen Boride Nanosheets.

ACS nano
2026

Effectiveness of Stapedotomy in Improving Audibility and Quality of Life in Patients with Unilateral Otosclerosis - A Retrospective Study.

International archives of otorhinolaryngology
2026

Efficient persistent afterglow modulation using extended Indolo[2,3-a]carbazoles with six-membered rings in a polymer matrix.

Chemical science
2026

Wildland-urban interface co-combustion of biomass, synthetic polymeric materials, and lithium-ion batteries generates a new class of ultrafine soot-metal-PAH hybrid particles.

Frontiers in public health
2026

Comprehensive evaluation of cardiovascular risk control in a large national cohort: insights from over 1 million participants in a cardiovascular prevention program.

Frontiers in public health
2026

Solvent-Based Separation of PA6 and PET Using Solubility Data from Differential Scanning Calorimetry.

Industrial & engineering chemistry research
2026

Comparative Study between Chonchal Cartilage Tympanoplasty and Temporalis Facia Tympanoplasty by Underlay Technique.

Journal of pharmacy & bioallied sciences
2026

Monday mood decline after weekend ecstasy use: A retrospective analysis of daily diary reports.

Drug and alcohol dependence reports
2026

Construction, validation, and nitrogen nutrition diagnosis of a critical nitrogen concentration model for cotton.

Frontiers in plant science
2026

Thermodynamic Study of Amine-Based Deep Eutectic Solvents with H2O.

Journal of chemical and engineering data
2026

Alkyne Two-Phase Strategy: Rapid Generation of TK-285-Derived PROTACs as BRD4 Degraders.

Journal of medicinal chemistry
2026

Antimicrobial Activity and Metabolomic Profiling of Secondary Metabolites From Endophytic Bacteria Associated With Prunus africana.

Chemistry & biodiversity
2026

AC measurements and magnetic properties of magnesium ferrite and its composites with reduced graphene oxide (rGO) and polypyrrole (PPy).

Scientific reports
2026

The fundamental localization phases in quasiperiodic systems: a unified framework and exact results.

Science bulletin
2025

Effect of adjuvant endocrine therapy on recurrence and contralateral breast cancer in HR-positive DCIS after mastectomy.

Breast (Edinburgh, Scotland)
2026

Evaluation of CAD-CAM methods for fabrication of removable partial denture frameworks from commercially pure titanium.

Journal of prosthodontic research
2026

Histamine Production by Photobacterium spp. in Tuna and Mahi-mahi under Various Storage Temperatures.

Journal of food protection
2026

Microbial conversion of waste-derived short-chain fatty acids into poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV): A review.

International journal of biological macromolecules
2026

Heterogeneous catalysis triggered in the novel copper-palladium spinel oxides through electron delocalization and oxygen vacancies for efficient degradation of organic contaminants.

Journal of environmental management
2026

Interface hyperfine coupling engineering of graphene oxide@MgAl-LDH architectures toward eco-efficient lithium extraction from salt-lake brines.

Journal of colloid and interface science
2026

3D Unconventional Superconductivity in Bulk LaO.

Journal of the American Chemical Society
2026

Evaluation and Surgical Management of Adult Spastic Hip and Knee Deformities.

JBJS reviews
2026

Effect of rhythmic auditory stimulation (RAS)® with and without melody on Parkinson's disease (PD) patients with deep brain stimulation (DBS): A study protocol.

PloS one
2026

Synergistic Regulation of Additive's Steric Hindrance and Amino Group Flexibility Enables All-Bromide Pure Blue Perovskite Light-Emitting Diodes.

Inorganic chemistry
2026

Cocoa flavanol supplementation and prevention of cardiovascular disease: a novel analysis of the COSMOS randomized trial using "win ratio".

European journal of epidemiology
2026

Inference for cause-specific cox model absolute risk in cohort subsampling designs.

Lifetime data analysis
2026

A Map is More Than a Polygon: Contesting Green Infrastructure in Forested Landscapes in Sweden.

Environmental management
2026

Biocatalytic processes in ionic liquids: a green platform for a sustainable future.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
2026

Droplet-like Na/Vacancy Ordering Enables Ultrahigh-Na-Content P2-Type Oxide Cathodes.

Journal of the American Chemical Society
2026

Using Mandatory Sales Reports to Monitor Same-Day Alcohol Delivery Trends in New South Wales.

Drug and alcohol review
2026

Crystals as Rockets: Modulation of the Salient Temperature in Cocrystals by Solvent Mixture Composition.

Angewandte Chemie (International ed. in English)
2026

Realizing High-Performance Vacuum-Deposited Inverted α-FAPbI3 Perovskite Solar Cells through Saturated-Humidity Annealing.

ACS applied materials & interfaces
2026

Threshold Switching Behavior and Underlying Mechanisms in Pure SiO2-Based Selectors.

ACS applied materials & interfaces
2026

A Stable Mesoporous Zeolite with Superlarge 36-Ring Channels.

Journal of the American Chemical Society
2026

Next-generation blue OLED emitters: efficiency, color purity, and the road to BT.2020.

Materials horizons
2026

Antifungal activity of metal-based coatings on polytunnel surfaces.

Journal of applied microbiology
2026

Invasive stratified mucin-producing carcinoma of the cervix: a report of 34 cases of immunohistochemical and clinicopathological findings.

Frontiers in oncology
2026

Coupling laboratory FTIR data with PROCODA kinetic modeling for the radiolysis of frozen formic acid using swift ions.

RSC advances
2026

Effect of oxygenated ferrocene derivatives on soot formation and nanoparticle emissions in n-heptane diffusion flames.

RSC advances
2026

A facile and practical method for the synthesis of trans-(±)-taxifolin and its derivatives via Darzens reaction.

Beilstein journal of organic chemistry
2026

Formation of cyclopentanes and cyclopropanes through alkylation of benzylic anions using ethers, thioethers and alcohols as substrates under Grubbs-Stoltz (Et3SiH/KOtBu) conditions.

Chemical science
2026

Antifluorite-derived Li7MnN4: revisiting the crystal structure and catalysis in ammonia decomposition.

Catalysis science & technology
2026

Low Temperature Oxygen Activation on the NiAg(100) Single-Atom Alloy Surface.

The journal of physical chemistry. C, Nanomaterials and interfaces
2026

Insights into Nonelectroactive C-C Bond Formation on Cu(100) during Electrochemical CO2 Reduction from Multiconfigurational Wavefunction Theory.

The journal of physical chemistry. C, Nanomaterials and interfaces
2026

Evaluating the Sulfo-Phospho-Vanillin Assay for Total Lipid Sample Normalization as Compared to Gravimetric and Protein Sample Normalization Methods for Untargeted Lipidomic LC-MS/MS.

Journal of the American Society for Mass Spectrometry
2026

Organotin(IV) Azo Hydrazonates as Lysosome-Targeted Imaging and Anticancer Agents.

Chemistry, an Asian journal
2026

Optofluidic light-droplet interaction for rapidly assessing the presence of plastic microspheres within aqueous suspensions.

Optics express
2026

Structural color based on a TiO2 semi-ellipsoidal nanostructures metasurface.

Optics express
2026

Clinical characteristics of ground-glass opacities in young patients : a single-center retrospective study.

Journal of cardiothoracic surgery
2026

Thickness-Deformation Collaborative Bandgap Control of Deep-Subwavelength Metallic Kirigami Metasurfaces.

ACS applied materials & interfaces
2026

Personalized 3D-Printed Finger Splints Derived from CT Data Incorporating Multi-Drug Bilayer Nanofiber Delivery Systems.

AAPS PharmSciTech
2026

Distinct metabolic profiles in lung adenocarcinomas presenting as solid or ground-glass opacities.

NPJ precision oncology
2026

Phase-Pure Thiophene-Based Quasi-2D Perovskite Single Crystals via Cosolvent-Controlled Crystallization.

The journal of physical chemistry letters
2026

Differential patterns of central synucleinopathy and catecholaminergic abnormalities in Lewy body diseases and multiple system atrophy.

Parkinsonism & related disorders
2026

Manufacturing Silk Fibroin Hollow Nanoyarns as Fundamental Units for Advanced Medical Textiles.

ACS applied materials & interfaces
2026

Two dimensional layered double hydroxides augment antigen loading and release.

Biomaterials advances
2026

ALS motor phenotypes: a revised 'OPM' classification.

Amyotrophic lateral sclerosis & frontotemporal degeneration
2026

Functional Pectin Film Modified by Chestnut Burr Polyphenols/Cinnamaldehyde Nano Emulsion via Microfluidization for Fruit Preservation.

Langmuir : the ACS journal of surfaces and colloids
2026

3D printing vs. conventional wax patterns: a comparative in vitro study on retention of RPD framework.

Odontology
2026

Low-Temperature CH4 Reforming and Water Splitting with Activated NiO/CeO2 as Oxygen Carrier.

Nano-micro letters
2026

Fungal contamination of commercial drinking water in Lagos, Nigeria.

Infection
2026

Thymic epithelial tumors at the crossroads of immunity, autoimmunity, and immunotherapy.

Cancer immunology, immunotherapy : CII
2026

Pure Endoscopic Suboccipital Supracerebellar Approach for Resection of Pineal Region Lesions.

The Journal of craniofacial surgery
2026

Idiopathic Musical Ear Syndrome in a Young Adult: A Case Report and Therapeutic Response.

American journal of audiology
2026

Association of CT Features with Radiologic Patterns in Interstitial Lung Disease: Multinomial Analysis in CARE-PF.

Radiology
2026

Antisymmetric Mueller generator as the universal origin of geometric phase in classical polarization and quantum two-level systems.

Journal of the Optical Society of America. A, Optics, image science, and vision
2026

Simultaneous measurement of atmospheric temperature and pressure profiles based on the lidar scattering spectrum under low-SNR conditions.

Applied optics
2025

Underwater image restoration via adaptive color balance and multi-purpose oriented contrast enhancement.

Applied optics
2025

Angle-to-retardance converter and a universal polarization-state synthesizer.

Applied optics
2026

DNN-enhanced spatially offset Raman spectroscopy for non-destructive subsurface material characterization.

Applied optics
2026

Optical dispersion and band gap of Silicon-SiO2 quantizing nanolaminates.

Applied optics
2025

Blind deconvolution extraction of Doppler-broadened spectra in LIF spectroscopy under model-free constraints.

Applied optics
2026

Ellipticity and astigmatism compensation in a double-pass AOM setup via the generalized ABCD matrix approach.

Applied optics
2026

High-efficiency generation of Bessel-Gaussian vortex beams using Bessel-phase-embedded fork-shaped holograms.

Applied optics
2026

MOF Ceramic-Like Membrane With High Proton Conduction and Tunable Transparency.

Angewandte Chemie (International ed. in English)
2026

Structural evolution of BaMoO4 upon Zn doping and its influence on electrochemical behavior in hybrid supercapacitors.

Dalton transactions (Cambridge, England : 2003)
2026

Critical comments on ultrasound-guided paravertebral oxygen-ozone injections.

Journal of back and musculoskeletal rehabilitation
2026

Subnanometric Platinum-Germanium Clusters for Efficient Propane Dehydrogenation Catalysis.

Small (Weinheim an der Bergstrasse, Germany)
2026

Mixed Forestation Outperforms Pure Stands in Soil Carbon Sequestration and Stability.

Global change biology
2026

Antioxidant polymer nanoparticles ameliorate cancer cachexia via intestinal ROS scavenging.

Journal of clinical biochemistry and nutrition
2026

Humidity-Induced Tristate Magnetic Switching in a Self-Healing High-Spin Cluster Material.

Journal of the American Chemical Society
2026

Organophosphonate Ligation Approach for the Controlled Assembly of Gigantic Polyoxometalate Clusters.

Journal of the American Chemical Society
2026

Room-Temperature Framework Oxygen Isotope Exchange during Interaction of Water with Hydrophilic Pure-Silica Zeolites Studied Using Nuclear Magnetic resonance Spectroscopy and Neutron Diffraction.

Journal of the American Chemical Society
2026

Eucalyptus lignin production coupled with Cellic ® CTec3 HS enzymatic hydrolysis to monosaccharides.

Applied microbiology and biotechnology
2026

Pathways for sustainable reaction kinetics in Li-CO2 batteries.

Nature communications
2026

Influence of Oxygen Partial Pressure on Sputtered NiOx Film Characteristics and Deep Interface Trap Density in NiOx/β-Ga2O3 Heterojunction Diodes.

ACS applied materials & interfaces
2026

Fabrication of Electroconductive PVDF Membranes: Hierarchical Architectures for Synergistic Biofouling Suppression and Electrochemical Regeneration.

ACS applied materials & interfaces
2026

Phase Diagram of 2D Poly(Ethylene Oxide)-block-Poly(Propylene Oxide)-block-Poly(Ethylene Oxide)─Poly(Dimethylsiloxane) Blends: A Combined Neutron Reflectometry and Sum Frequency Generation Study.

Langmuir : the ACS journal of surfaces and colloids
2026

Long-term farming and cropping systems with contrasting nitrogen forms and input diversity influence soil prokaryotic diversity in the central highlands of Kenya.

PloS one
2026

Swertiamarin fails to induce cytotoxicity in colon cancer cell lines: Evidence against a direct anticancer effect.

PloS one
2026

Thermodynamically Consistent Enthalpies of Adsorption of Mixtures from Classical Density Functional Theory.

The journal of physical chemistry. B
2026

Low Complication Rate Following Contemporary Pure Anteriorization Tibial Tubercle Osteotomy for Patellofemoral Chondral Wear in Patients Aged Less Than 50 Years.

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
2026

Targeting TNBC: core-shell polycationic polyurea dendrimers with inherent anticancer activity.

FEBS open bio
2026

Ice-rubber friction mechanisms across scales.

Soft matter
2026

Thermodynamic discontinuity in evaporating thin solvated nematics.

The Journal of chemical physics
2026

Quantum dynamics of water dissociation on a Cu/Ni(111) bimetallic alloy surface: A nine-dimensional model.

The Journal of chemical physics
2026

Impact of Various Essential Oils or Their Pure Components on the Selected Properties and Microbicidal Potential of Chitosan-Based Coatings.

Langmuir : the ACS journal of surfaces and colloids
2026

Asymmetric Michael Addition of 3-Chlorooxindoles with Vinylidene Bisphosphonates: Synthesis of 3,3-Disubstituted 3-Chlorooxindoles and Spirocyclopropane-Fused Oxindoles.

The Journal of organic chemistry
2026

How Realistic Are Idealized Copper Surfaces? A Machine Learning Study of Rough Copper-Water Interfaces.

ACS materials Au
2026

Zr6O4(OH)4(O2C-t-Bu)12 precursor uncovers how modulators govern supersaturation, nucleation, and growth of UiO-66 nanocrystals.

Chemical science
2026

Resonance Raman and Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS) Analysis of Biological Polyenes in Shells: A Nondestructive Approach for Species and Habitat Identification.

ACS omega
2026

Research on Synergistic Permeability Enhancement Technology of Staged Fracturing Acidification in Low-Permeability Coal Reservoirs.

ACS omega
2026

Mussel-Inspired Strong Adhesive for Sand Fixation Based on Tannic Acid with Analysis of Adhesion Mechanisms.

ACS omega
2026

Sol-Gel Synthesis of SnO2/Zn2-SnO4 Heterostructure for the Photocatalytic Degradation of Malachite Green.

ACS omega
2026

Enhanced Charge Separation and Visible-Light Utilization in La-Doped MIL-100(Fe) for Efficient Cr(VI) Photoreduction.

ACS omega
2026

Antimicrobial and Photocatalytic Properties under Visible Blue LED Light of Silver Phosphate Supported on Biogenic Zeolite from Amazon Natural Source.

ACS omega
2026

Evaluating Claudin-6 and isochromosome 12p in the progression from germ cell neoplasia in situ to primary testicular germ cell tumor and post-chemotherapy teratoma: implications for CLDN6-targeted therapies.

Therapeutic advances in medical oncology
2026

Understanding strain localization in metallic materials: a review of high-resolution digital image correlation and related techniques.

Science and technology of advanced materials

Associações

Organizações que acompanham esta doença — pra ter apoio e orientação

Ainda não temos associações cadastradas para Paraplegia espástica hereditária pura ou complexa.

É de uma associação que acompanha esta doença? Fale com a gente →

Comunidades

Grupos ativos de quem convive com esta doença aqui no Raras

Ainda não existe comunidade no Raras para Paraplegia espástica hereditária pura ou complexa

Pacientes, familiares e cuidadores se organizam em comunidades pra compartilhar experiências, fazer perguntas e se apoiar. Você pode ser o primeiro.

Tire suas dúvidas

Perguntas, dicas e experiências compartilhadas aqui na página

Participe da discussão

Faça login para postar dúvidas, compartilhar experiências e interagir com especialistas.

Fazer login

Doenças relacionadas

Doenças com sintomas parecidos — ajudam quem ainda está buscando diagnóstico

Ainda não achamos doenças com sintomas parecidos o suficiente.

Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Copper-hydroxyl interactions drive water-promoted copper surface oxidation and mobility.
    Nature communications· 2026· PMID 41872192mais citado
  2. Pre-monsoon aerosol intensification and enhanced atmospheric warming over the South-Eastern Arabian Sea.
    Environmental science and pollution research international· 2026· PMID 41870717mais citado
  3. Impact of cardiometabolic criteria on the pathogenesis of MASLD and diagnostic performance of non-invasive tests.
    Journal of gastroenterology· 2026· PMID 41870616mais citado
  4. Synthesis of gold nanorod@Pd(Pt)-Cu2O dendritic nanocomposites for plasmon-enhanced photocatalysis.
    Journal of colloid and interface science· 2026· PMID 41865708mais citado
  5. Thermo-Transitioning Core-Shell Microgels Combine Cohesive Reinforcement and Noncohesive Reconfigurability to Enable 3D Bioprinting and Stabilize Tissues During Incubation.
    ACS biomaterials science & engineering· 2026· PMID 41863836mais citado
  6. Associations between hearing, subjective memory complaints, and dementia risk factors among audiology clients.
    Int J Audiol· 2026· PMID 41871138recente
  7. Sentinel Lymph Node Biopsy for Desmoplastic Melanoma: A Systematic Review and Meta-analysis.
    Ann Surg Oncol· 2026· PMID 41870859recente
  8. Hanseniaspora uvarum and Hanseniaspora opuntiae differ in their growth and in the production of volatile organic compounds in wine.
    Appl Microbiol Biotechnol· 2026· PMID 41870620recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:320335(Orphanet)
  2. MONDO:0017913(MONDO)
  3. GARD:21429(GARD (NIH))
  4. Q55346012(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Paraplegia espástica hereditária pura ou complexa
Compêndio · Raras BR

Paraplegia espástica hereditária pura ou complexa

ORPHA:320335 · MONDO:0017913
MedGen
UMLS
C5679885
EuropePMC
Wikidata
DiscussaoAtiva

Nenhuma novidade ainda. O agente esta monitorando.

0membros
0novidades