Raras
Buscar doenças, sintomas, genes...
Neurorretinopatia macular aguda
ORPHA:488239CID-10 · H35.3CID-11 · 9B65.0DOENÇA RARA
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Introdução

O que você precisa saber de cara

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Síndromes de pontos brancos são doenças inflamatórias caracterizadas pela presença de pontos brancos no fundo do olho, a superfície interna do olho. A maioria dos indivíduos afetados pelas síndromes de pontos brancos tem menos de cinquenta anos de idade. Alguns sintomas incluem visão turva e perda de campo visual. Existem muitas teorias para a etiologia das síndromes de pontos brancos, incluindo causas infecciosas, virais, genéticas e autoimunes.

Publicações científicas
347 artigos
Último publicado: 2026 Apr 7

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
<1 / 1 000 000
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
0.0
Worldwide
Casos conhecidos
101
pacientes catalogados
Início
Adolescent
+ adult
🏥
SUS: Sem cobertura SUSScore: 0%
CID-10: H35.3
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Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico347PubMed
Últimos 10 anos200publicações
Pico202342 papers
Linha do tempo
2026Hoje · 2026🧪 2018Primeiro ensaio clínico📈 2023Ano de pico
Publicações por ano (últimos 10 anos)

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Genética e causas

O que está alterado no DNA e como passa nas famílias

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Nenhum gene associado encontrado

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Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

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Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

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·Pré-clínico1
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 1 ensaio
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Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Neurorretinopatia macular aguda

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Selecione um estado ou use sua localização para ver resultados.

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Ensaios clínicos abertos e novidades científicas recentes

Pesquisa e ensaios clínicos

1 ensaios clínicos encontrados.

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Publicações mais relevantes

Timeline de publicações
264 papers (10 anos)
#1

Viral mechanisms, tropism, and clinical relevance regarding the ophthalmic manifestations of SARS-CoV-2 infection.

International journal of ophthalmology2026

To explore the mechanisms underlying ocular infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), we conducted a comprehensive review of current literature, focusing on viral entry pathways, receptor expression in ocular tissues, and associated clinical manifestations. This review encompasses studies published within the last five years with a focus on original research and systematic reviews that provide molecular, histological, or clinical evidence. The findings show that SARS-CoV-2 can infect ocular tissues through multiple receptors beyond angiotensin-converting enzyme 2 (ACE2), including transmembrane serine protease 2 (TMPRSS2), CD147, alanyl aminopeptidase N (ANPEP), dipeptidyl peptidase 4 (DPP4), angiotensin II receptor type 2 (AGTR2), and polymeric immunoglobulin receptor (PIGR), which are expressed in retinal, conjunctival, corneal, limbal, and photoreceptor cells. The virus may also reach ocular structures via neurovascular invasion. Clinically, patients with coronavirus disease 2019 (COVID-19) may present with a broad spectrum of ophthalmic manifestations, including conjunctivitis, hyperreflective lesions in the inner retinal layers, flame-shaped hemorrhages, cotton-wool spots, retinal pallor, hard exudates, and various forms of maculopathy, such as paracentral acute middle maculopathy and acute macular neuroretinopathy (AMN). These signs reflect both direct viral damage and secondary effects of systemic inflammation and microvascular injury. Understanding the molecular and clinical spectrum of ocular involvement is essential for early diagnosis, appropriate ophthalmologic care, and the prevention of long-term visual sequelae in patients affected by COVID-19.

#2

Choroidal vascular changes in eyes with acute macular neuroretinopathy and paracentral acute middle maculopathy: new insights.

BMC ophthalmology2026 Feb 11

To assess choroidal vasculature changes in acute macular neuroretinopathy (AMN) and paracentral acute middle maculopathy (PAMM) during the acute and resolution phases. Retrospective, cross-sectional study. Twenty-eight eyes from 28 patients were analyzed: 8 with AMN and 20 with PAMM. Also, 30 healthy age-matched controls were included. Clinical records and spectral-domain optical coherence tomography (SD-OCT) scans from patients with AMN and PAMM were assessed. Choroidal assessment was performed using an automated algorithm, binarized into stromal choroidal areas (SCA) and luminal choroidal areas (LCA). Choroidal vascularity index (CVI) was calculated as the ratio of LCA to total choroidal area (TCA). Statistical analysis was performed using non-parametric tests. The median age was 54 years (IQR = 32-68.5), and 60.7% were female. AMN eyes showed significantly increased subfoveal choroidal thickness (SFCT), TCA, SCA, and LCA compared to PAMM and controls (p = 0.044, p = 0.007, p = 0.002, p = 0.014 respectively). No differences in CVI were observed between the groups (p = 0.535). These findings remained consistent when comparing AMN with isolated PAMM and PAMM associated with retinal vascular diseases (p < 0.05). SFCT, TCA, SCA, and LCA significantly decreased in AMN eyes (p = 0.045, p = 0.041, p = 0.040, p = 0.038 respectively) after resolution, while no changes were observed in PAMM (p > 0.05). Also, resolved AMN exhibited higher SFCT, TCA, SCA and LCA compared to controls and resolved PAMM eyes (p < 0.05). Increased choroidal thickness is a characteristic feature of AMN, with reduction observed after resolution. On the other hand, no changes were observed in PAMM, suggesting distinct pathophysiological mechanisms between the two conditions.

#3

Acute Macular Neuroretinopathy in Association with Orbital Inflammation and Optic Perineuritis.

Neuro-ophthalmology (Aeolus Press)2026

A 17-year-old girl experienced acute onset of decreased vision with pain on movement in her left eye. Her best-corrected visual acuity was 20/20 in the right eye and 20/100 in the left eye. Pupillary examination revealed a positive relative afferent pupillary defect. Fundus examination showed optic disc hyperemia and retinal folds. A central scotoma was detected on a perimetry test. Fluorescein angiography indicated mild disc leakage in the late phase. Orbital magnetic resonance imaging disclosed enhancement in the soft tissue of the left retrobulbar area and at the sheath of the left optic nerve. Optical coherence tomography (OCT) revealed subretinal fluid at the fovea, disruption of the ellipsoid zone (EZ), a hyper-reflective band at the outer plexiform layer (OPL), and hyper-reflective foci (HRF) in the inner retinal layer. Pulse therapy was administered, followed by oral steroid tapering. One week later, OCT showed almost complete resolution of subretinal fluid, no HRF, partial improvement in the thickening of the OPL, but persistent EZ disruption. One month later, her vision in the left eye improved to 0.6. Here we present a rare case of AMN associated with orbital inflammation and optic perineuritis, mimicking acute optic neuritis. Although the status of myelin oligodendrocyte glycoprotein (MOG) antibodies in our patient remains uncertain, her ophthalmologic manifestations strongly suggest myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). This study highlights the importance of OCT examination, especially macular scanning, for establishing a proper diagnosis.

#4

Acute Macular Outer Retinopathy and Acute Vision Loss Associated With Electrolyte Derangements and Rapid Repletion.

Journal of vitreoretinal diseases2026 Jan 28

Purpose: To describe a unique case of acute macular outer retinopathy presenting immediately after rapid correction of severe hypokalemia and hypomagnesemia, and to explore the potential association between electrolyte repletion and outer retinal injury. Methods: A single clinical case was retrospectively reviewed. Results: A 29-year-old woman presented with acute macular outer retinopathy and vision loss immediately following rapid intravenous electrolyte replacement. Optical coherence tomography revealed disruption of the outer retinal layers, and microperimetry demonstrated a corresponding decrease in retinal sensitivity. The patient was monitored over 5 months without intervention and achieved visual stability with partial improvement of outer retinal structure on imaging. Conclusions: This case highlights a potential relationship between rapid variations in systemic electrolyte concentrations and the development of acute macular outer retinopathy. The findings emphasize the importance of caution during rapid electrolyte repletion and suggest that multimodal retinal imaging may be valuable in monitoring visual symptoms that arise during or after electrolyte correction.

#5

COVID-19-related acute macular neuroretinopathy in China: a retrospective study of 90 cases (152 eyes).

International journal of retina and vitreous2026 Feb 28

Publicações recentes

Ver todas no PubMed

📚 EuropePMC282 artigos no totalmostrando 196

2026

Viral mechanisms, tropism, and clinical relevance regarding the ophthalmic manifestations of SARS-CoV-2 infection.

International journal of ophthalmology
2026

COVID-19-related acute macular neuroretinopathy in China: a retrospective study of 90 cases (152 eyes).

International journal of retina and vitreous
2026

Choroidal vascular changes in eyes with acute macular neuroretinopathy and paracentral acute middle maculopathy: new insights.

BMC ophthalmology
2026

Acute Macular Neuroretinopathy in Association with Orbital Inflammation and Optic Perineuritis.

Neuro-ophthalmology (Aeolus Press)
2026

Acute Macular Outer Retinopathy and Acute Vision Loss Associated With Electrolyte Derangements and Rapid Repletion.

Journal of vitreoretinal diseases
2026

Acute macular neuroretinopathy in the context of autoimmune demyelinating disease of the central nervous system.

Medicina clinica
2025

Clinical efficacy and mechanisms of hyperbaric oxygen therapy in the treatment of rheumatic and immune diseases.

Frontiers in medicine
2025

Influenza-Associated Ocular Complications: A Comprehensive Review of Viral Subtypes, Clinical Presentations, and Vaccination Risks.

Vaccines
2025

Bilateral acute macular neuroretinopathy after Epstein-Barr virus encephalitis.

American journal of ophthalmology case reports
2025

Acute macular neuroretinopathy in COVID-19 patients: Short-term prospective follow-up observation.

Photodiagnosis and photodynamic therapy
2025

Noninfectious Uveitis Syndromes.

Advances in experimental medicine and biology
2025

Acute macular neuroretinopathy after Covid 19 in an eye with a congenital retinal macrovessel - a case report.

American journal of ophthalmology case reports
2025

The characteristics of multimodal fundus imaging in AMN patients following COVID infection.

Scientific reports
2025

Acute Macular Neuroretinopathy Mediated by COVID-19 Infection: Insights into its Clinical Features and Pathogenesis.

Frontiers in bioscience (Landmark edition)
2025

A case of acute macular neuroretinopathy in a pediatric patient with optic neuritis.

American journal of ophthalmology case reports
2025

Paracentral Acute Middle Maculopathy in a Pregnant Woman on Supplemental Hormones for Invitro-Fertilization.

Advanced emergency nursing journal
2025

Atypical presentation of acute macular neuroretinopathy: a case description.

Quantitative imaging in medicine and surgery
2025

Consensus disease definitions for ophthalmic immune-related adverse events of immune checkpoint inhibitors.

Journal for immunotherapy of cancer
2025

Acute macular neuroretinopathy associated with dengue virus infection.

Archivos de la Sociedad Espanola de Oftalmologia
2025

Acute Macular Neuroretinopathy Following COVID-19 Infection: A Case Report.

Cureus
2025

ACUTE MACULAR NEURORETINOPATHY FOLLOWING MODERNA mRNA COVID-19 VACCINATION.

Retinal cases &amp; brief reports
2025

Bilateral acute macular neuroretinopathy following influenza A infection.

IDCases
2025

Atypical COVID-19-Related Acute Macular Neuroretinopathy with Progression Resulting in Severe Vision Loss.

Case reports in ophthalmology
2025

Foveal Cavitations by High-resolution OCT after Acute Macular Neuroretinopathy.

Ophthalmology. Retina
2025

Acute bilateral macular neuroretinopathy in a 12-year-old boy following a flu-like illness: a microperimetric longitudinal follow-up.

Clinical &amp; experimental optometry
2025

Case series on 2 cases of macular damage caused by the novel coronavirus: A case report.

Medicine
2025

Acute macular neuroretinopathy occurrence in a Behçet disease patient: a case report.

Journal of ophthalmic inflammation and infection
2024

Retinal Capillary Ischemia Following Migraine: A Case Report.

Cureus
2025

A case of acute macular neuroretinopathy as atipycal ICANS manifestation after CAR-T cell infusion.

Leukemia &amp; lymphoma
2024

A cross-sectional study of fundus lesion characteristics in patients with acute visual impairment caused by COVID-19 infection.

Scientific reports
2025

Acute macular neuroretinopathy in SARS-CoV-2 infection and the utility of the Spectralis® High Magnification Module HMM®.

Journal francais d'ophtalmologie
2024

Case report: Acute macular neuroretinopathy post-COVID-19 infection.

Optometry and vision science : official publication of the American Academy of Optometry
2023

Acute Macular Neuroretinopathy after COVID-19 Infection: Clinical Characteristics and Associated Factors.

Ophthalmology. Retina
2025

Acute macular neuroretinopathy associated with migraine.

Archivos de la Sociedad Espanola de Oftalmologia
2024

Acute Macular Neuroretinopathy Associated with COVID-19 Pandemic: A Real-world Observation Study.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)
2024

Acute macular neuroretinopathy following COVID-19 infection: Three case reports.

World journal of clinical cases
2024

Manifestations of COVID-19 in the posterior eye segment - Up-to-date.

Oman journal of ophthalmology
2024

Optical coherence tomography characteristics and prognostic predictors of acute macular neuroretinopathy following SARS-CoV-2 infection.

Indian journal of ophthalmology
2024

[Clinical characteristics of acute macular neuroretinopathy in China associated with COVID-19 infection].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology
2024

Type II Acute Macular Neuroretinopathy Secondary to Malaria.

Case reports in ophthalmological medicine
2024

Multicenter and multimodal imaging study reveals rare fundus lesions in patients after SARS-CoV-2 infection.

Scientific reports
2024

Unveiling the metabolic and coagulation disruptions in SARS-CoV-2-associated acute macular neuroretinopathy: A case-control study.

Journal of medical virology
2024

Bilateral acute macular neuroretinopathy associated with COVID-19 infection presenting with central scotoma.

American journal of ophthalmology case reports
2025

The Characteristics of White Dot Syndromes Following SARS-COV-2 Infection: A Systematic Review.

European journal of ophthalmology
2024

Safety analysis of Oseltamivir and Baloxavir Marboxil after market approval: a pharmacovigilance study based on the FDA adverse event reporting system.

BMC infectious diseases
2024

Acute macular neuroretinopathy following Valsalva manoeuvre: an insight into the pathophysiology.

BMJ case reports
2024

The characteristics of white dot syndromes following COVID-19 Vaccines: a systematic review.

International ophthalmology
2025

Acute Macular Neuroretinopathy After COVID-19 Infection in a Patient With Multiple Sclerosis.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
2024

Case report: dengue fever associated acute macular neuroretinopathy.

Frontiers in medicine
2024

A Subtle Case of Type 2 Acute Macular Neuroretinopathy.

Rhode Island medical journal (2013)
2024

Optical coherence tomography angiography suggests choriocapillaris perfusion deficit as etiology of acute macular neuroretinopathy.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
2024

Outer Retinopathies Associated with COVID-19 Infection: Case Reports and Review of Literature.

Case reports in ophthalmological medicine
2024

Purtscher-Like Retinopathy and Acute Macular Neuroretinopathy in a Child with Acute Influenza A.

Retina (Philadelphia, Pa.)
2024

Clinical Spectrum of Ophthalmic Manifestations in Myelin Oligodendrocyte Glycoprotein-Associated Disease (MOGAD): A Comprehensive Case Report.

Ocular immunology and inflammation
2024

Ocular Complications after COVID-19 Vaccination: A Systematic Review.

Medicina (Kaunas, Lithuania)
2024

Acute macular neuroretinopathy and COVID-19 or SARS-CoV-2 infection: case report and literature review.

Frontiers in medicine
2025

COVID-19 as a Potential Risk Factor for Acute Macular Neuroretinopathy.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
2024

Acute macular neuroretinopathy following uncomplicated epiretinal membrane removal.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
2023

Case report: A case of Acute Macular Neuroretinopathy secondary to Influenza A virus during Long COVID.

Frontiers in immunology
2024

The characteristics of acute macular neuroretinopathy following COVID-19 infection.

BMC ophthalmology
2023

Acute Macular Neuroretinopathy after SARS-CoV-2 Infection: An Analysis of Clinical and Multimodal Imaging Characteristics.

Diagnostics (Basel, Switzerland)
2023

Case Report: Acute Macular Neuroretinopathy Which Led to COVID-19 Infection Diagnosis.

Beyoglu eye journal
2023

Long-term follow-up of a young male who developed acute macular neuroretinopathy following COVID-19 vaccination.

Clinical case reports
2023

[Acute macular neuroretinopathy: a case report].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology
2023

Choroidal Circulatory and Vascular Morphological Changes in Acute Macular Neuroretinopathy After Infection With Severe Acute Respiratory Syndrome Coronavirus 2: A Case Report With Literature Review.

In vivo (Athens, Greece)
2024

RETINAL OPTICAL COHERENCE TOMOGRAPHY IMAGING BIOMARKERS: A Review of the Literature.

Retina (Philadelphia, Pa.)
2023

COVID-19 Related Acute Macular Neuroretinopathy (AMN): A Case Series.

International medical case reports journal
2023

Clinical and Diagnostic Findings of Acute Macular Neuroretinopathy and Paracentral Acute Middle Maculopathy in the COVID-19 Era.

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde
2023

An alarming rise in COVID-19-related acute macular neuroretinopathy in China: a cross-sectional multimodal imaging study.

Journal of travel medicine
2023

Optical coherence tomography angular hyperreflectivity as an early sign in acute macular neuroretinopathy.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
2023

Acute macular neuroretinopathy as a manifestation of COVID-19 infection.

Journal francais d'ophtalmologie
2023

Transient Increase in Patient Numbers with "Acute Macular Neuroretinopathy" Post SARS-CoV-2 Infection-Case Series During the First Surge of Infection in December 2022.

Journal of inflammation research
2023

Concomitant paracentral acute middle maculopathy and acute macular neuroretinopathy in eyes post-blunt trauma.

Indian journal of ophthalmology
2023

Photoreceptor Misalignment Contributes to Imaging Features During Acute Macular Neuroretinopathy.

JAMA ophthalmology
2023

Photoreceptor Misalignment Contributes to Imaging Features During Acute Macular Neuroretinopathy-Reply.

JAMA ophthalmology
2023

Acute macular neuroretinopathy following Moderna COVID-19 vaccination.

Journal of ophthalmic inflammation and infection
2023

ACUTE MACULAR NEURORETINOPATHY FOLLOWING SARS-CoV-2 VACCINATION.

Retinal cases &amp; brief reports
2023

A Case of Concurrent Acute Macular Neuroretinopathy and Paracentral Acute Middle Maculopathy Following Pfizer-BioNTech COVID-19 Vaccination.

Turkish journal of ophthalmology
2023

BILATERAL ACUTE MACULAR NEURORETINOPATHY IN ACUTE COVID-19 INFECTION: A CASE STUDY.

Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti
2023

Clinical and multimodal imaging features of acute macular neuroretinopathy lesions following recent SARS-CoV-2 infection.

International journal of ophthalmology
2024

Bilateral Acute Macular Neuroretinopathy (AMN) after COVID-19 and its Clinical Course.

Klinische Monatsblatter fur Augenheilkunde
2023

Coincident Acute Macular Neuroretinopathy and Paracentral Acute Middle Maculopathy in COVID-19.

Turkish journal of ophthalmology
2023

TRAUMA-RELATED ACUTE MACULAR NEURORETINOPATHY. A CASE REPORT.

Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti
2023

Optical coherence tomography angiography features of dengue retinopathy manifesting as acute macular neuroretinopathy, branch vein vasculitis and neurosensory detachment.

Oman journal of ophthalmology
2023

In the Eye of the Cytokine Storm: A Tale of SARS-CoV-2-Induced Acute Macular Neuroretinopathy.

Cureus
2024

HIGH-RESOLUTION IMAGING OF THE OUTER RETINA IN TYPE 2 ACUTE MACULAR NEURORETINOPATHY.

Retinal cases &amp; brief reports
2023

Paracentral Acute Middle Maculopathy As the Presenting Sign of Ischemic Cardiomyopathy.

Cureus
2023

Acute Macular Neuroretinopathy Associated With COVID-19 Infection: Is Double Heterozygous Methylenetetrahydrofolate Reductase (MTHFR) Mutation an Underlying Risk Factor?

Cureus
2023

Acute Macular Neuroretinopathy and Paracentral Acute Middle Maculopathy during SARS-CoV-2 Infection and Vaccination.

Vaccines
2023

Structural Changes in Acute Macular Neuroretinopathy Revealed With Adaptive Optics Optical Coherence Tomography.

JAMA ophthalmology
2023

Case Report: Recurrent Acute Macular Neuroretinopathy-Monitoring Recovery with Multimodal Imaging.

Optometry and vision science : official publication of the American Academy of Optometry
2023

Acute macular neuroretinopathy secondary to central retinal artery occlusion.

American journal of ophthalmology case reports
2023

Retinal vascular occlusions in COVID-19 infection and vaccination: a literature review.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
2023

Acute macular neuroretinopathy and COVID-19 vaccination: Case report and literature review.

Journal francais d'ophtalmologie
2022

Deep Capillary Plexus Features in Acute Macular Neuroretinopathy: Novel Insights Based on the Anatomy of Henle Fiber Layer.

Investigative ophthalmology &amp; visual science
2022

Multimodal Imaging and Macular Hyalocyte Count in a Patient with Acute Macular Neuroretinopathy.

Case reports in ophthalmological medicine
2024

Acute Macular Neuroretinopathy Associated With Idiopathic Intracranial Hypertension.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
2023

Acute Macular Neuroretinopathy and Coronavirus Disease 2019.

Ophthalmology. Retina
2022

Acute macular neuroretinopathy following COVID-19 infection.

The New Zealand medical journal
2023

Acute macular neuroretinopathy in a patient with birdshot chorioretinopathy after intravitreal triamcinolone suspension injection.

European journal of ophthalmology
2022

Acute Macular Neuroretinopathy Following COVID-19 mRNA Vaccination.

Cureus
2022

Acute macular neuroretinopathy associated with intravitreal anti-VEGF injection: A case report.

American journal of ophthalmology case reports
2023

[COVID-19-associated acute macular neuroretinopathy].

Die Ophthalmologie
2024

Acute Macular Neuroretinopathy Associated With Acute Syphilitic Infection Mimicking Optic Neuritis.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
2023

Bilateral Acute Macular Neuroretinopathy after COVID-19 Vaccination and Infection.

Ocular immunology and inflammation
2022

COVID-19 and Acute Macular Neuroretinopathy - An underlying association?

Annals of medicine and surgery (2012)
2022

Acute macular neuroretinopathy after COVID-19 vaccine.

Journal francais d'ophtalmologie
2022

Ischemic retinal events after COVID-19 vaccination.

American journal of ophthalmology case reports
2022

Neuro-Ophthalmological Complications of the COVID-19 Vaccines: A Systematic Review.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
2023

Presumed Post-COVID Infection Retinitis - Clinical and Tomographic Features of Retinitis as a Post-COVID Syndrome.

Ocular immunology and inflammation
2022

Acute macular neuroretinopathy associated to dengue disease.

American journal of ophthalmology case reports
2022

Branch Retinal Artery Occlusions, Paracentral Acute Middle Maculopathy and Acute Macular Neuroretinopathy After COVID-19 Vaccinations.

Clinical ophthalmology (Auckland, N.Z.)
2023

Acute macular neuroretinopathy as the first stage of SARS-CoV-2 infection.

European journal of ophthalmology
2022

A Sudden Rise of Patients with Acute Macular Neuroretinopathy during the COVID-19 Pandemic.

Case reports in ophthalmology
2022

Ocular Complications Following Vaccination for COVID-19: A One-Year Retrospective.

Vaccines
2022

Topographical Relationship Between Acute Macular Neuroretinopathy and Choroidal Watershed Zone or Patchy Choroidal Filling.

Frontiers in medicine
2022

Anti-Programmed Death Ligand-1 Induced Acute Vision Loss in a Patient With Cancer-Associated Retinopathy.

Cureus
2023

Hyperbaric Oxygen Therapy Combined with Immunosuppression for Acute Macular Neuroretinopathy in Systemic Lupus Erythematosus.

Ocular immunology and inflammation
2022

Bilateral acute macular neuroretinopathy in a young woman after the first dose of Oxford-AstraZeneca COVID-19 vaccine.

American journal of ophthalmology case reports
2022

Acute macular neuroretinopathy in dengue virus serotype 1.

American journal of ophthalmology case reports
2022

Two Cases of Acute Macular Neuroretinopathy Associated with the Adenovirus-based COVID-19 Vaccine Vaxzevria (Astrazeneca).

Ocular immunology and inflammation
2022

Bilateral Sequential Acute Macular Neuroretinopathy in an Asian Indian Female with β Thalassemia Trait following (Corona Virus Disease) COVID-19 Vaccination and Probable Recent COVID Infection - Multimodal Imaging Study.

Ocular immunology and inflammation
2021

Differentiation between acute macular neuroretinopathy and paracentral acute middle maculopathy in elderly persons: two case reports.

BMC ophthalmology
2022

[Acute macular neuroretinopathy: En face OCT description, case series].

Journal francais d'ophtalmologie
2021

Uveitis and Other Ocular Complications Following COVID-19 Vaccination.

Journal of clinical medicine
2022

Acute macular neuroretinopathy and COVID-19 vaccination.

Indian journal of ophthalmology
2021

Multimodal imaging of type 2 acute macular neuroretinopathy in a young woman.

Digital journal of ophthalmology : DJO
2023

Tacrolimus Induced Thrombotic Microangiopathy (TMA) Presenting as Acute Macular Neuroretinopathy.

Ocular immunology and inflammation
2021

Retinal Vascular Events after mRNA and Adenoviral-Vectored COVID-19 Vaccines-A Case Series.

Vaccines
2022

Cerebral malaria associated with mixed forms of acute macular neuroretinopathy and paracentral acute middle maculopathy.

Journal francais d'ophtalmologie
2021

Acute macular neuroretinopathy associated with COVID-19 infection.

American journal of ophthalmology case reports
2021

Did the COVID-19 Pandemic Increase the Incidence of Acute Macular Neuroretinopathy?

Journal of clinical medicine
2021

Vitreoretinal abnormalities in corona virus disease 2019 patients: What we know so far.

Taiwan journal of ophthalmology
2021

Acute macular neuroretinopathy as a manifestation of coronavirus disease 2019: A case report.

Clinical case reports
2023

Acute Macular Neuroretinopathy Secondary to Rickettsia typhi Infection.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
2022

ACUTE MACULAR NEURORETINOPATHY AFTER SARS-COV-2 VACCINATION.

Retinal cases &amp; brief reports
2022

ACUTE MACULAR NEURORETINOPATHY AFTER COVID-19 VACCINATION.

Retinal cases &amp; brief reports
2021

Retinal and choroidal manifestations of COVID-19.

Current opinion in ophthalmology
2021

Acute macular neuroretinopathy (AMN) following COVID-19 vaccination.

American journal of ophthalmology case reports
2021

Bilateral paracentral acute middle maculopathy and acute macular neuroretinopathy following COVID-19 vaccination.

Indian journal of ophthalmology
2021

Maculopathy Masquerading as Migraine.

Vision (Basel, Switzerland)
2021

Ocular Adverse Events After COVID-19 Vaccination.

Ocular immunology and inflammation
2021

Acute macular neuroretinopathy following Pfizer-BioNTech COVID-19 vaccination.

American journal of ophthalmology case reports
2021

Association of Ocular Adverse Events With Inactivated COVID-19 Vaccination in Patients in Abu Dhabi.

JAMA ophthalmology
2021

Bilateral Acute Macular Neuroretinopathy After Vaccination Against SARS-CoV-2.

JAMA ophthalmology
2022

Coincident PAMM and AMN and Insights Into a Common Pathophysiology.

American journal of ophthalmology
2021

Acute macular outer retinopathy as a presumed manifestation of COVID-19.

Journal francais d'ophtalmologie
2021

Acute Macular Neuroretinopathy following Coronavirus Disease 2019 Vaccination.

Ocular immunology and inflammation
2022

Acute macular neuroretinopathy following COVID-19 vaccination.

Eye (London, England)
2021

A Patient-Centered Integrative Approach Improves Visual Field Defect: A Case Report.

Global advances in health and medicine
2021

Acute Macular Neuroretinopathy in a Patient with Retinal Vascular Tortuosity.

Case reports in ophthalmology
2021

Acute Macular Neuroretinopathy Related to Alcoholic Hepatitis.

Case reports in ophthalmology
2022

Bilateral acute macular neuroretinopathy following COVID-19 infection.

Acta ophthalmologica
2022

ACUTE MACULAR NEURORETINOPATHY AS THE PRESENTING MANIFESTATION OF COVID-19 INFECTION.

Retinal cases &amp; brief reports
2021

Low Visual Acuity Due to Acute Macular Neuroretinopathy Associated with COVID-19: A Case Report.

The American journal of case reports
2021

Acute macular neuroretinopathy in a 22-year-old woman.

Journal francais d'ophtalmologie
2021

Acute macular neuroretinopathy in a case of chronic lymphocytic leukemia.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
2021

Acute macular neuroretinopathy associated with acute promyelocytic leukemia.

American journal of ophthalmology case reports
2021

Paracentral acute middle maculopathy in patient with atherosclerosis and angioplasty with stents in the coronary artery.

Einstein (Sao Paulo, Brazil)
2021

Association of Acute Macular Neuroretinopathy or Paracentral Acute Middle Maculopathy with Sickle Cell Disease.

Ophthalmology. Retina
2020

Twelve-Year-Old Girl with Acute Macular Neuroretinopathy: A Multimodal Retinal Evaluation.

Case reports in ophthalmology
2021

Acute macular neuroretinopathy in a patient with acute myeloid leukemia and deceased by COVID-19: a case report.

Journal of ophthalmic inflammation and infection
2020

Acute macular neuroretinopathy in a patient with acute coronary syndrome.

BMJ case reports
2022

[Long-term follow-up of a young female patient with bilateral acute macular neuroretinopathy].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
2021

Multimodal Imaging in Acute Macular Neuroretinopathy.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
2020

Covid-19-Associated Retinopathy: A Case Report.

Ocular immunology and inflammation
2021

Ophthalmic manifestations of myelin oligodendrocyte glycoprotein-IgG-associated disorder other than optic neuritis: a systematic review.

The British journal of ophthalmology
2020

Incidence of uveitis and macular edema among patients taking fingolimod 0.5 mg for multiple sclerosis.

Journal of ophthalmic inflammation and infection
2020

Retinal Diseases that Can Masquerade as Neurological Causes of Vision Loss.

Current neurology and neuroscience reports
2020

[Optical coherence tomography angiography in the diagnosis of retinal microangiopathy in atypical hemolytic-uremic syndrome (a case report)].

Vestnik oftalmologii
2020

Concurrent vascular flow defects at the deep capillary plexus and choriocapillaris layers in acute macular neuroretinopathy on multimodal imaging: A case series.

American journal of ophthalmology case reports
2020

Acute Macular Neuroretinopathy Associated With an Oral FLT3 Inhibitor.

JAMA ophthalmology
2020

Differences in the multicolour imaging features between the superficial and deep vascular occlusions.

International ophthalmology
2020

Paracentral Acute Middle Maculopathy.

Turkish journal of ophthalmology
2020

Paracentral acute middle maculopathy and acute macular neuroretinopathy following SARS-CoV-2 infection.

Eye (London, England)
2020

Influenza-Induced Acute Macular Neuroretinopathy With Cerebral Involvement in a Ten-Year-Old Boy.

Ophthalmic surgery, lasers &amp; imaging retina
2021

Multimodal Imaging Characteristics and Functional Test Findings in a Case of Acute Macular Neuroretinopathy Accompanied by Behçet Disease.

Ocular immunology and inflammation
2020

Acute macular neuroretinopathy.

The Medical journal of Australia
2020

Acute Macular Neuroretinopathy in Purtscher Retinopathy.

Turkish journal of ophthalmology
2020

Bilateral Acute Macular Neuroretinopathy in a Young Patient: Imaging and Visual Field during Two-Year-Follow-Up.

Diagnostics (Basel, Switzerland)
2020

Improvement of deep capillary and choroidal blood void in optical coherence tomography angiography in a case of acute macular neuroretinopathy after prednisolone treatment.

Journal of the Formosan Medical Association = Taiwan yi zhi
2020

Hypoperfusion of the deep capillary plexus associated with acute on chronic cocaine use.

American journal of ophthalmology case reports
2020

Acute macular neuroretinopathy with coexistent central retinal vein occlusion as the presenting feature in intraocular tuberculosis.

Journal of ophthalmic inflammation and infection
2020

Clinical and Morphological Characteristics of Anti-Programmed Death Ligand 1-Associated Retinopathy: Expanding the Spectrum of Acute Macular Neuroretinopathy.

Ophthalmology. Retina
2019

C-Shaped Scotoma after Complicated Cesarean Section: A Case of Acute Macular Neuroretinopathy.

Case reports in ophthalmology
2020

Optical Coherence Tomography Angiography Recovery Pattern of Acute Macular Neuroretinopathy.

JAMA ophthalmology
2019

Acute macular neuroretinopathy (AMN) related to energy drink consumption.

BMJ case reports
2019

[White dot syndromes : Principles, diagnostics, and treatment].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
2019

Acute Macular Neuroretinopathy in Behçet Disease.

Ophthalmology. Retina
2021

Acute Macular Neuroretinopathy Associated with Acute Influenza Virus Infection.

Ocular immunology and inflammation
2020

[Acute macular neuroretinopathy in a 13-year-old female patient with focal choroidal excavation and pachychoroid disease].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
2019

Management of Deep Retinal Capillary Ischemia by Electromagnetic Stimulation and Platelet-Rich Plasma: Preliminary Clinical Results.

Advances in therapy
2019

Optical Coherence Tomography Angiography (OCT-A) in a Patient with Occult Retinal Dysfunction.

Case reports in ophthalmological medicine
2019

Microvascular change in acute macular neuroretinopathy by using optical coherence tomography angiography.

Taiwan journal of ophthalmology
2019

Increased thickness and decreased blood flow velocity of the choroid in a patient with acute macular neuroretinopathy.

BMC ophthalmology
2018

High-Dose Sildenafil-associated Acute Macular Neuroretinopathy Variant.

Ophthalmology. Retina
Ver todos os 282 no EuropePMC

Associações

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Comunidades

Grupos ativos de quem convive com esta doença aqui no Raras

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Doenças relacionadas

Doenças com sintomas parecidos — ajudam quem ainda está buscando diagnóstico

Ainda não achamos doenças com sintomas parecidos o suficiente.

Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Viral mechanisms, tropism, and clinical relevance regarding the ophthalmic manifestations of SARS-CoV-2 infection.
    International journal of ophthalmology· 2026· PMID 41767314mais citado
  2. Choroidal vascular changes in eyes with acute macular neuroretinopathy and paracentral acute middle maculopathy: new insights.
    BMC ophthalmology· 2026· PMID 41673823mais citado
  3. Acute Macular Neuroretinopathy in Association with Orbital Inflammation and Optic Perineuritis.
    Neuro-ophthalmology (Aeolus Press)· 2026· PMID 41640497mais citado
  4. Acute Macular Outer Retinopathy and Acute Vision Loss Associated With Electrolyte Derangements and Rapid Repletion.
    Journal of vitreoretinal diseases· 2026· PMID 41626078mais citado
  5. COVID-19-related acute macular neuroretinopathy in China: a retrospective study of 90 cases (152 eyes).
    International journal of retina and vitreous· 2026· PMID 41764537mais citado
  6. Acute Macular Neuroretinopathy in a 27-year-old male patient following impending central retinal vein occlusion.
    Retin Cases Brief Rep· 2026· PMID 41944604recente
  7. Ultra-high-resolution imaging of acute macular neuroretinopathy: a case report.
    Am J Ophthalmol Case Rep· 2026· PMID 41939080recente
  8. Swept-Source OCT Characterization of Dengue Retinopathy: Novel Grading System and Laminar Linear Retinal Hyperreflectivity.
    Photodiagnosis Photodyn Ther· 2026· PMID 41905657recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:488239(Orphanet)
  2. MONDO:0044627(MONDO)
  3. GARD:22000(GARD (NIH))
  4. Busca completa no PubMed(PubMed)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Compêndio · Raras BR

Neurorretinopatia macular aguda

ORPHA:488239 · MONDO:0044627
Prevalência
<1 / 1 000 000
Casos
101 casos conhecidos
CID-10
H35.3 · Degeneração da mácula e do pólo posterior
CID-11
Início
Adolescent, Adult
Prevalência
0.0 (Worldwide)
MedGen
UMLS
C5200735
EuropePMC
Papers 10a
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