É uma doença inflamatória rara dos grandes vasos sanguíneos, que afeta principalmente a artéria aorta e seus principais ramos, mas também outros grandes vasos, causando estreitamento, bloqueio ou aneurisma.
Introdução
O que você precisa saber de cara
É uma doença inflamatória rara dos grandes vasos sanguíneos, que afeta principalmente a artéria aorta e seus principais ramos, mas também outros grandes vasos, causando estreitamento, bloqueio ou aneurisma.
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
1/2k
Encontrou um erro ou informação desatualizada? Sugira uma correção →
Entender a doença
Do básico ao detalhe, leia no seu ritmo
Preparando trilha educativa...
Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Partes do corpo afetadas
+ 30 sintomas em outras categorias
Características mais comuns
Os sintomas variam de pessoa para pessoa. Abaixo estão as 54 características clínicas mais associadas, ordenadas por frequência.
Linha do tempo da pesquisa
Encontrou um erro ou informação desatualizada? Sugira uma correção →
Genética e causas
O que está alterado no DNA e como passa nas famílias
Genes associados
3 genes identificados com associação a esta condição. Padrão de herança: Not applicable.
Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation
CytoplasmNucleus
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates t
Secreted
Immunodeficiency 29
A form of Mendelian susceptibility to mycobacterial disease, a rare condition caused by impairment of interferon-gamma mediated immunity. It is characterized by predisposition to illness caused by moderately virulent mycobacterial species, such as Bacillus Calmette-Guerin (BCG) vaccine, environmental non-tuberculous mycobacteria, and by the more virulent Mycobacterium tuberculosis. Other microorganisms rarely cause severe clinical disease in individuals with susceptibility to mycobacterial infections, with the exception of Salmonella which infects less than 50% of these individuals. Clinical outcome severity depends on the degree of impairment of interferon-gamma mediated immunity. Some patients die of overwhelming mycobacterial disease with lepromatous-like lesions in early childhood, whereas others develop, later in life, disseminated but curable infections with tuberculoid granulomas. IMD29 is characterized by undetectable IL12B secretion from leukocytes. Affected individuals generally present with BCG disease after vaccination in childhood, and at least half also have Salmonella infection. Disease phenotype is relatively mild, and patients have a good prognosis.
Antigen-presenting major histocompatibility complex class I (MHCI) molecule. In complex with B2M/beta 2 microglobulin displays primarily viral and tumor-derived peptides on antigen-presenting cells for recognition by alpha-beta T cell receptor (TCR) on HLA-B-restricted CD8-positive T cells, guiding antigen-specific T cell immune response to eliminate infected or transformed cells (PubMed:23209413, PubMed:25808313, PubMed:29531227, PubMed:9620674). May also present self-peptides derived from the
Cell membraneEndoplasmic reticulum membrane
Stevens-Johnson syndrome
A rare blistering mucocutaneous disease that share clinical and histopathologic features with toxic epidermal necrolysis. Both disorders are characterized by high fever, malaise, and a rapidly developing blistering exanthema of macules and target-like lesions accompanied by mucosal involvement. Stevens-Johnson syndrome is a milder disease characterized by destruction and detachment of the skin epithelium and mucous membranes involving less than 10% of the body surface area. Ocular symptoms include ulcerative conjunctivitis, keratitis, iritis, uveitis and sometimes blindness. It can be caused by a severe adverse reaction to particular types of medication, although Mycoplasma infections may induce some cases.
Variantes genéticas (ClinVar)
62 variantes patogênicas registradas no ClinVar.
Vias biológicas (Reactome)
14 vias biológicas associadas aos genes desta condição.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Arterite de Takayasu
Selecione um estado ou use sua localização para ver resultados.
Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.
Pesquisa ativa
Ensaios clínicos abertos e novidades científicas recentes
Ensaios em destaque
🟢 Recrutando agora
18 pesquisas recrutando participantes. Converse com seu médico sobre a possibilidade de participar.
Outros ensaios clínicos
75 ensaios clínicos encontrados, 27 ativos.
Publicações mais relevantes
Mostrando amostra de 200 publicações de um total de 2.004
Systematic Review and Meta-Analysis for JCS 2026 Guideline on Management of Large-Vessel Vasculitis.
To provide evidence from randomized controlled trials (RCTs) for large-vessel vasculitis (LVV), including Takayasu arteritis (TAK) and giant cell arteritis (GCA), to inform the forthcoming 2026 Japanese Circulation Society (JCS) clinical practice guideline. We drafted 4 and 7 clinical questions for TAK and GCA, respectively. A systematic review (SR) of RCTs was conducted using PubMed, CENTRAL, EMBASE, and the Japan Medical Abstracts Society through March 2024. Assessed with the GRADE approach, the certainty of evidence was very low for the most critical outcomes, low for some outcomes, and moderate for only 1 outcome. Evidence for TAK was limited. Tocilizumab (TCZ) resulted in a numerically lower relapse rate vs. placebo (risk ratio (RR) 0.73, 95% confidence interval (CI) 0.39-1.37) and was similar to adalimumab. No clear difference between mycophenolate mofetil (MMF) and methotrexate (MTX), or between abatacept (ABA) and placebo was observed. In GCA, TCZ reduced relapse (RR 0.29, 95% CI 0.09-0.98) and increased remission (RR 3.56, 95% CI 2.29-5.54) over placebo at 52 weeks. Tumor necrosis factor inhibitor, ABA, and MTX showed no benefit in cranial GCA. Serious adverse events were comparable between treatment groups. Geographic variation and differences in entry criteria were noted. This SR was comprehensive synthesis of evidence from RCTs for LVV therapies to support the 2026 JCS guideline.
Pregnancy complicated by Takayasu arteritis and recurrent pregnancy loss.
A young woman (G4P2L0A1) diagnosed with a case of Takayasu arteritis (Type IV) and a history of recurrent pregnancy loss presented at 7 weeks of gestation with chronic hypertension. She was on immunosuppressive and antihypertensive therapy preconceptionally. At 29 weeks, she developed a hypertensive emergency with stage 2 fetal growth restriction. Despite aggressive management, blood pressure (BP) remained elevated (up to 200/110 mm Hg). A preterm caesarean section was performed at 31 weeks under steroid cover, resulting in the delivery of a 1.45 kg male neonate. Both mother and baby had uneventful recoveries, and the patient achieved the target BP by discharge.
Current and Future Treatments for Takayasu Arteritis: Toward Cardiovascular Risk Modification.
Takayasu arteritis (TAK) is a rare, immune-mediated large-vessel vasculitis that affects predominantly young women and carries a substantial risk of both vascular complications and long-term cardiovascular disease. Although glucocorticoids and conventional immunosuppressive therapies remain the cornerstone of treatment, relapse rates are high, and current strategies fail to adequately mitigate future cardiovascular risk. This review synthesizes evidence on current treatment strategies, unmet clinical needs, and novel approaches, including immunological and vascular-targeted therapies, and argues for a shift in management paradigm toward integrated cardiovascular risk reduction. We discuss advances in understanding the pathogenesis of TAK, highlighting the roles of innate and adaptive immunity in disease progression, and the challenges of early diagnosis and disease monitoring. We critically appraise current treatment paradigms, including glucocorticoids, conventional disease-modifying antirheumatic drugs, and biologics such as tocilizumab and tumor necrosis factor-α inhibitors, and outline emerging therapies targeting novel pathways, including interleukin-17, interleukin-12/23, Janus kinase/signal transducer and activator of transcription, and Notch-1/mammalian target of rapamycin complex signaling. We highlight the increasing recognition of cardiovascular morbidity as a major contributor to mortality in TAK and the need for integrated approaches to risk factor modification. We explore a road map for advancing management of cardiovascular disease in TAK, including comprehensive screening tools that integrate serological and imaging biomarkers to interrogate cardiovascular risk and potential therapeutic cardioprotective strategies such as sodium-glucose cotransporter 2 inhibitors and endothelin receptor antagonists. Despite recent progress, clinical management remains limited by diagnostic uncertainty, heterogeneous treatment approaches, and a paucity of high-quality randomized controlled trials. Future work should focus on interventions that target both immune-mediated vascular injury and cardiovascular disease progression. Achieving long-term disease remission while reducing cardiovascular mortality must become the primary therapeutic goal in TAK.
[Analysis of follow-up and prognosis in pediatric rheumatic diseases associated with pulmonary embolism].
Objective: To explore the clinical characteristics, diagnosis and treatment strategies, and prognosis of pulmonary embolism (PE) complicating childhood rheumatic diseases. Methods: A retrospective case series study was performed on the demographic data, laboratory indicators, imaging features, treatment regimens, and follow-up data of 8 children with rheumatic diseases complicated by PE who were admitted to the Department of Rheumatology and Immunology, Capital Center for Children's Health, Capital Medical University from January 2014 to October 2023. Results: Among the 8 children, there were 4 boys and 4 girls, with an age of 12.0 (7.5, 13.0) years. Among the primary diseases, there were 3 cases of systemic lupus erythematosus, 2 cases of Behçet's disease, 2 cases of Takayasu arteritis, and 1 case of antiphospholipid syndrome. All children developed PE during the active phase of the primary disease. PE was detected at the onset of the primary disease in 3 cases, and the median time from the diagnosis of the primary disease to the development of PE was 10.0 (6.0, 25.0) months in the remaining 5 cases. Fever was present in all 8 children, 4 cases were accompanied by chest tightness, dyspnea, etc., and 2 cases only presented with fever. Laboratory examinations revealed the following results: erythrocyte sedimentation rate was 42.0 (17.0, 78.0) mm/1 h, high-sensitivity C-reactive protein was 12.7 (2.6, 78.7) mg/L, white blood cell count was 9.6 (7.2, 18.7)×109/L; D-dimer was 2.3 (0.9, 6.2) mg/L; and hemoglobin was (109±16) g/L.Imaging examinations revealed that 5 cases had involvement of the bilateral lower pulmonary arteries, 5 cases had peripheral embolism, and 3 cases had central PE. Complications included 3 cases of deep vein thrombosis, 2 cases of intracranial venous sinus thrombosis, and 1 case of mild pulmonary hypertension.In terms of treatment, 7 cases received anticoagulation with heparin followed by warfarin. Immunomodulation was mainly based on glucocorticoids combined with immunosuppressants, and 4 cases were combined with biological agents. The follow-up time of 4.17 (1.75, 7.17) years, the time for complete absorption of PE was 10.5 (6.0, 18.0) months; all 8 children had no target events, with no recurrence or chronic thromboembolic pulmonary hypertension, and the pulmonary artery remodeling was good. Conclusions: PE complicating childhood rheumatic diseases is closely related to the activity of the primary disease. The clinical manifestations are insidious, with fever as the main symptom. Imaging examination is the key to diagnosis.Early adoption of heparin followed by warfarin anticoagulation and glucocorticoids combined with immunosuppressants and (or) biological agents to control the primary disease can achieve a favorable prognosis. 目的： 探讨儿童风湿病并发肺栓塞的临床特征、诊疗策略及预后。 方法： 回顾性病例系列研究，收集2014年1月至2023年10月首都医科大学附属首都儿童医学中心风湿免疫科收治的8例风湿病并发肺栓塞患儿的人口学资料、实验室指标、影像学特征、治疗方案及随访资料。 结果： 8例患儿中，男、女各4例，就诊年龄12.0（7.5，13.0）岁。8例患儿原发病中系统性红斑狼疮3例，白塞病2例、多发性大动脉炎2例、抗磷脂综合征1例。所有患儿均在原发病活动期发生肺栓塞，3例患儿于首次就诊时发现，5例患儿肺栓塞的发病时间距原发病确诊时间为10.0（6.0，25.0）个月。临床表现中发热8例，伴胸闷、呼吸困难4例等，2例患儿仅表现为发热。实验室检查显示8例患儿中红细胞沉降率42.0（17.0，78.0）mm/1 h，高敏C反应蛋白12.7（2.6，78.7）mg/L，白细胞计数9.6（7.2，18.7）×10⁹/L；D二聚体2.3（0.9，6.2）mg/L；血红蛋白（109±16）g/L。影像学检查示8例患儿中双下肺动脉受累5例，周围型栓塞5例，中心型肺栓塞3例；3例患儿合并深静脉血栓，2例伴颅内静脉窦血栓，1例轻度肺动脉高压。治疗方面7例患儿采用肝素序贯华法林抗凝，免疫调节以糖皮质激素联合免疫抑制剂为主，4例联用生物制剂。随访4.17（1.75，7.17）年，所有患儿肺栓塞完全吸收时间为10.5（6.0，18.0）个月，8例患儿经随访，均无目标事件发生，无复发或慢性血栓栓塞性肺动脉高压，肺动脉重构良好。 结论： 儿童风湿病并发肺栓塞与原发病活动密切相关，临床表现隐匿，以发热为主要表现，影像学检查是诊断关键，早期采用肝素序贯华法林抗凝及糖皮质激素联合免疫抑制剂和（或）生物制剂控制原发病可获良好预后。.
JCS 2026 Guideline on Management of Large Vessel Vasculitis.
Publicações recentes
[Pathomorphological features of various etiological forms of aortic aneurysm].
A Silent Vasculitis With a Loud Presentation: Takayasu Arteritis Causing Intracerebral Hemorrhage.
Carotid steal syndrome with recurrent syncope: A novel manifestation of Takayasu arteritis.
Burned out Takayasu arteritis in a young caucasian female: A rare case of aortic regurgitation and aneurysm requiring surgical repair.
Metabolic-Epigenetic Crosstalk in Takayasu Arteritis: The ANK2-MAVS-IL-8 Axis as a Novel Therapeutic Paradigm.
📚 EuropePMC2.243 artigos no totalmostrando 197
Coexistence of Sjögren's disease and Takayasu arteritis in a woman: a case-based review.
Clinical rheumatologyDifferential Vascular Response to Corticosteroid Therapy in Takayasu Arteritis Revealed by Serial FDG-PET Imaging.
European journal of nuclear medicine and molecular imagingJCS 2026 Guideline on Management of Large Vessel Vasculitis.
Circulation journal : official journal of the Japanese Circulation SocietyManagement of Takayasu Arteritis - A 2026 Update.
Current rheumatology reportsTherapeutic effect of tofacitinib combined with leflunomide for refractory Takayasu arteritis: pilot study.
Seminars in arthritis and rheumatismHematopoietic Stem Cell Transplantation in Rheumatic Diseases.
International journal of rheumatic diseasesConstruction and internal cohort verification of clinical-imaging-based nomogram for early diagnosis in Takayasu arteritis.
Frontiers in medicineUnilateral Graves disease with Takayasu arteritis.
JCEM case reportsRisk factors of serious infections in patients with large-vessel vasculitis after the approval of tocilizumab in 2017: a retrospective nested case-control study using the Japanese health insurance database.
Arthritis research & therapyPathogenetic Gut Microbiota in Aortic Diseases: Evidence and Mechanisms Across Aneurysm, Dissection, and Inflammatory Aortopathies.
NutrientsThe rheumatry registry: design and data collection methods.
BMC rheumatologyStent insertion for chronic total occlusion of the common carotid artery in a patient with Takayasu arteritis using an adjunctive retrograde approach via superficial temporal artery puncture: illustrative case.
Journal of neurosurgery. Case lessonsEmbolic Myocardial Infarction from Takayasu Arteritis.
CASE (Philadelphia, Pa.)Utility of contrast-enhanced ultrasound for assessing disease activity in takayasu arteritis with carotid artery involvement: a scoping review.
Frontiers in immunologyCoexistence of Takayasu Arteritis and Intestinal Tuberculosis in a Young Bangladeshi Woman.
Clinical case reportsStroke characteristics in giant cell arteritis and Takayasu arteritis: A multicenter retrospective cohort study of 108 patients.
Seminars in arthritis and rheumatismDefinitions and online reliability assessment of elementary ultrasound lesions in Takayasu arteritis: a study from the OMERACT Ultrasound Working Group.
Seminars in arthritis and rheumatismSystematic Review and Meta-Analysis for JCS 2026 Guideline on Management of Large-Vessel Vasculitis.
Circulation journal : official journal of the Japanese Circulation SocietyDeficiency of transcription factor E4BP4 suppresses neointimal formation after vascular injury.
AtherosclerosisLong-Term Follow-Up in Patients with Large-Vessel Vasculitis Applying Extracranial and Transcranial Duplex Sonography.
Diagnostics (Basel, Switzerland)Takayasu Arteritis Presenting With Cardiac Arrest: An Intravascular Imaging Triggered Diagnosis.
JACC. Case reportsSalvage therapy with JAK inhibitors in refractory Takayasu arteritis: a multicentre experience.
RMD openAutoantibodies and B Cells in Takayasu Arteritis and Giant Cell Arteritis: Comparative Insights into Large-Vessel Vasculitis.
The Tohoku journal of experimental medicineMesenteric Steal Syndrome Caused by Abdominal Aortic Stenosis due to Takayasu Arteritis.
Surgical case reportsBeating the Odds: Successful Emergent Surgery After Acute Aortic Dissection in Takayasu Arteritis.
CureusInternal carotid artery involvement and stroke risk in Takayasu arteritis: a case-control study.
Rheumatology international[Non-infectious neuroretinitis: diagnostic and therapeutic approach in unusual presentations].
MedicinaA rare case of midaortic syndrome: Vascular Behçet's disease or Takayasu arteritis?
Turk gogus kalp damar cerrahisi dergisiMaternal and perinatal outcomes in vasculitis: a 15-year study at a Portuguese tertiary multidisciplinary centre.
Rheumatology advances in practiceIntestinal obstruction associated with middle aortic syndrome: A case report.
The Journal of international medical researchClinical Images: Bilateral common iliac aneurysms in Takayasu arteritis with consequent obstructive uropathy.
Arthritis & rheumatology (Hoboken, N.J.)Exploring the Correlations between Initial Clinical and Radiological Manifestations in Takayasu's Arteritis.
Arquivos brasileiros de cardiologiaReversal of chronic arterial stenosis with biologic therapy including tocilizumab in Takayasu arteritis.
Modern rheumatology case reportsTherapeutic management of inflammatory heart diseases.
Pharmacology & therapeuticsPregnancy complicated by Takayasu arteritis and recurrent pregnancy loss.
BMJ case reportsCurrent and Future Treatments for Takayasu Arteritis: Toward Cardiovascular Risk Modification.
CirculationSubclavian artery stenosis in hemodialysis patients: a case series and review of the literature.
Frontiers in pharmacologyErdheim-Chester disease mimicking IgG4-related disease.
Modern rheumatology case reportsTakayasu Arteritis-Induced Acute Myocardial Infarction: Coronary Imaging- and Physiology-Guided Management.
JACC. Case reportsProximal Right Coronary Artery Stenosis Secondary to Surgical Suture After Aortic Root Replacement.
JACC. Case reportsDistinguishing Takayasu Arteritis and Giant Cell Arteritis Based on Large-Vessel Involvement Patterns.
Yonsei medical journalClaudication and Hypertension From Aortic Occlusion in Takayasu Arteritis: Revascularization With Excimer Laser and Drug-Eluting Stent.
Vascular and endovascular surgeryTakayasu Arteritis in a Middle-aged Woman Following Prolonged Subsequent Fever after COVID-19 Infection: An Early Diagnosis Using Contrast-Enhanced CT.
Internal medicine (Tokyo, Japan)Outcomes of an Intravenous to Subcutaneous Infliximab (CT-P13) Strategy in Takayasu Arteritis: A Proof-of-Concept Prospective Study.
ACR open rheumatologyTakayasu Arteritis Presenting as Stress-Induced Chest Pain.
Mayo Clinic proceedingsAssociation of genetic variants with extravascular complications and cytokine production in Takayasu arteritis: a cross-sectional study.
Rheumatology advances in practiceChest pain in an adolescent revealing a sinus of Valsalva aneurysm secondary to Takayasu arteritis.
Cardiology in the youngSilent inflammation, stormy presentation: bilateral renal artery stenosis secondary to Takayasu arteritis.
The Journal of invasive cardiologyImmunosuppressive Therapy in Takayasu Arteritis: A Tightrope Walk Between Inflammation and Infection.
CureusDiverse Vascular Manifestations of Takayasu Arteritis: Coronary Artery Stenosis and Aneurysmal Dilation in pediatric patients.
Clinical medicine insights. Arthritis and musculoskeletal disordersClinical Implications of Vasculitis Associated with Familial Mediterranean Fever: A Comparative Study in Childhood.
Modern rheumatologyTakayasu Arteritis in a 55-Year-Old Woman With Prior Mycobacterium leprae Infection: A Possible Postinfectious Association.
Clinical case reportsSevere Pediatric Takayasu Arteritis Presenting With Cerebral Ischemia and Supra-Aortic Trunk Occlusion.
CureusPostpartum watershed strokes as initial manifestation of a rare co-occurrence of systemic lupus erythematosus and Takayasu Vasculitis: A case report of neuroimmunologic and literature review.
eNeurologicalSci[Analysis of follow-up and prognosis in pediatric rheumatic diseases associated with pulmonary embolism].
Zhonghua er ke za zhi = Chinese journal of pediatricsCase Report: Takayasu Arteritis During Upadacitinib Therapy for Ulcerative Colitis Successfully Treated by Combination Therapy With Methotrexate.
International journal of rheumatic diseasesA case of Takayasu arteritis with advanced macrovascular lesions due to 6 years from onset to diagnosis.
Pediatrics international : official journal of the Japan Pediatric SocietyIncidence of pulmonary hypertension in patients with Takayasu's arteritis: A transthoracic echocardiographic evaluation.
Reumatologia clinicaCarotid sonographic features in Takayasu's arteritis: A case-control study.
Caspian journal of internal medicineInvolvement of Iliofemoral Arteries in PET/CT Is Associated with Atherosclerotic Risk Factors in Takayasu's Arteritis.
Journal of clinical medicineConcurrent seronegative spondyloarthropathy and Takayasu's arteritis: a case report and literature review.
Diagnostic pathologyImproving outcomes in proximal anastomosis: A challenging case of coronary revascularization in Takayasu arteritis.
JTCVS techniquesClinical and laboratory predictors of diagnostic delay in childhood Takayasu arteritis and PAN: a retrospective cohort study.
Rheumatology (Oxford, England)FAPI PET in the Diagnosis and Management of Inflammatory Diseases: Clinical Value and Future Perspectives.
Clinical nuclear medicine[Annuloaortic Ectasia Induced by Takayasu's Arteritis:Report of a Case].
Kyobu geka. The Japanese journal of thoracic surgeryA Case of Isolated Aortic Regurgitation, Later Diagnosed as Takayasu Arteritis: An Importance of Physical Examinations.
Clinical case reportsMaternal-fetal outcomes and therapeutic strategies in pregnancies complicated by Takayasu arteritis: a comprehensive analysis.
Arthritis research & therapyLarge Vessel Vasculitis: Multimodality Imaging Findings and Technical Principles.
Radiographics : a review publication of the Radiological Society of North America, IncEndovascular repair of infrarenal aortic aneurysm and severe stenosis in Type V Takayasu arteritis: a rare case report and clinical insights.
The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of CardiologyImmunogenicity and safety to SARS-Cov-2 vaccination in patients with systemic vasculitis.
Frontiers in immunologyOpen surgical revascularization after IL-6 blockade for Takayasu arteritis: A case report.
International journal of surgery case reportsHyperinflammatory status associated with COVID-19: clinical features of a pediatric series.
Advances in rheumatology (London, England)Lymphoma risk in autoimmune diseases with multiple medication use: analysis from the LIFE Study.
Blood cancer journalCardioembolic stroke in Takayasu arteritis treated with dual stent retriever via brachial access: A case report.
Radiology case reportsThe Role of Imaging in Monitoring Large Vessel Vasculitis: A Comprehensive Review.
BiomoleculesApplications and challenges of paclitaxel- coated balloons beyond coronary atherosclerotic heart disease.
World journal of clinical casesAdolescent-Onset Takayasu Arteritis with Vertebral Steal Syndrome and Non-bifurcating Carotid Arteries: A Rare Case from Pakistan.
Clinical medicine insights. Case reportsTechnical Tips for Surgical Treatment of Takayasu Arteritis.
Vascular specialist internationalPhysical activity in systemic vasculitis.
European journal of internal medicineThe Role of FDG-PET in the Diagnosis and Monitoring of Large-Vessel Vasculitis.
Current rheumatology reportsPostpartum Hybrid Aortic Aneurysm Repair in the Setting of Takayasu Arteritis.
The Annals of thoracic surgeryA Rare Case of Takayasu Arteritis and Aortic Aneurysm in a Male Patient.
CureusAdvancing the understanding of age-specific phenotypes in childhood-onset takayasu arteritis.
Pediatric researchANK2-MAVS signaling dysfunction triggers mitochondrial stress and enhances IL-8 mediated inflammatory responses in Takayasu arteritis.
Free radical biology & medicineA visual guide for emergency radiologists navigating the complexity of abdominal vasculitis: part 1 - true vasculitis.
Emergency radiology[Expert consensus for the diagnosis and treatment of pediatric Takayasu arteritis (2025)].
Zhonghua er ke za zhi = Chinese journal of pediatricsIntegrated bulk and single-cell transcriptomics identifies shared and specific immune signatures in Takayasu Arteritis.
Arthritis research & therapyTherapeutic plasma exchange in autoimmune diseases: a retrospective study in a tertiary pediatric hospital in Mexico.
Frontiers in pediatricsGenetic susceptibility and validation of angiographic patterns in Takayasu arteritis.
Journal of autoimmunityAdvances in the pathophysiology, diagnosis and treatment of Takayasu arteritis.
Nature reviews. RheumatologySyphilitic Cardiac and Vascular Disease: A Comprehensive Review.
Cardiology in reviewTakayasu arteritis presenting with severe biventricular dysfunction and renal artery stenosis in a pediatric patient: a case report.
Annals of medicine and surgery (2012)Beyond the Pulselessness: A Multifaceted Case of Takayasu Arteritis With Aneurysmal Complications and Extensive Upper Limb Vascular Occlusion in a 40-Year-Old Female.
Clinical case reportsDevelopment of Successive Thrombophlebitis and Takayasu Arteritis Associated With Crohn Disease in a Pediatric Patient: A Case Report.
The Journal of rheumatologyClinical Course After Transcatheter Aortic Valve Replacement for Takayasu Arteritis-Related Aortic Stenosis and Regurgitation.
JACC. Case reportsVasculitis syndromes: large vessel vasculitides and ANCA-associated vasculitides from a neuroradiologist's perspective.
Japanese journal of radiologyIL-1R/IL-6R blockade for null NLRP12 variant-carrying Takayasu arteritis.
Rheumatology (Oxford, England)An alternative catheter to invasive blood pressure monitoring in a patient with Takayasu arteritis undergoing open adrenalectomy: A case report.
MedicineTakayasu retinopathy unveiling underlying Takayasu arteritis: a case report.
BMC ophthalmologyMacaroni Sign in Takayasu Arteritis.
Mediterranean journal of rheumatology[Granuloma faciale and Takayasu arteritis in a child: a case report].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatricsClinical profile and long-term outcomes of pediatric-onset Takayasu's arteritis: data from a mexican national referral center.
Pediatric rheumatology online journalGene variants of glucocorticoid activation pathways and the outcomes of patients with Takayasu arteritis - a retrospective cohort study.
Frontiers in immunologySerum interleukin-1 receptor antagonist levels are a useful marker of disease activity and risk of relapse in large vessel vasculitis.
CytokineExploring the genetic interaction between ERAP1/ERAP2 and HLA-B*52:01 in Takayasu arteritis.
Rheumatology (Oxford, England)[Clinical characteristics and prognosis of childhood-onset Takayasu arteritis involving pulmonary artery].
Zhonghua er ke za zhi = Chinese journal of pediatricsDiagnostic delay and cardiovascular complications in Takayasu arteritis: a case-based review.
Rheumatology internationalTreatment of systemic vasculitis.
Current opinion in rheumatologyPosterior Reversible Encephalopathy Syndrome in a Young Female with Takayasu and Tubercular Arteritis: A Rare Case Report.
Annals of African medicineAn Atypical Presentation of Takayasu Arteritis: Isolated Tinnitus Followed by Ectopic Pregnancy.
CureusLong-term outcomes of aortic valve insufficiency in patients with Takayasu arteritis.
Frontiers in immunologyChildhood-onset Takayasu arteritis: Unique characteristics and outcomes from a Singapore cohort.
Annals of the Academy of Medicine, SingaporeNew avenues in childhood vasculitis.
Pediatric rheumatology online journalPregnancy in Takayasu Arteritis: A Case Report of Successful Pregnancy in a Large Aortic Aneurysm.
Clinical case reportsThe role of 18F-fluorodeoxyglucose positron emission tomography for vascular imaging.
Progress in cardiovascular diseasesA Systematic Review of the Use of Janus Kinase Inhibitors in Large Vessel Vasculitis.
CureusComparison of the 2022 ACR/EULAR classification criteria with the 1990 ACR classification criteria for Takayasu arteritis.
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOGMeta-Analysis of Carotid Contrast-Enhanced Ultrasonography to Assess the Activity of Takayasu Arteritis.
Journal of clinical ultrasound : JCUChildhood-onset Takayasu arteritis: clinical presentation, challenges and disease course.
Pediatric rheumatology online journalSuperior Aortic Recess Mimicking Takayasu Arteritis in a Patient With Adult-Onset Still's Disease.
CureusHigh prevalent early damage independently predicts future mortality in an inception cohort of Takayasu arteritis.
Rheumatology (Oxford, England)Age specific clinical manifestations and vascular involvements in childhood-onset Takayasu arteritis.
Pediatric researchOptic Disc and Retinal Structural Changes in Takayasu Arteritis: Implications for Normotensive Glaucoma.
Ocular immunology and inflammationPrevalence and clinical severity of takayasu arteritis angiographic types: a systematic review with meta-analysis.
Rheumatology internationalProblem analysis based on the international classification of functioning, disability and health (ICF) in patients with Takayasu arteritis.
Respiratory medicinePhenotypic clusters of patients with Takayasu arteritis predict disease activity at presentation, damage and future vascular complications.
Rheumatology (Oxford, England)Diagnostic Accuracy of Clinical Findings for Takayasu Arteritis: A Rapid Review and Meta-Analysis.
International journal of vascular medicineAortitis in Disguise: Cardiomyopathy in a Child With Takayasu Arteritis.
Circulation. Cardiovascular imagingTakayasu Arteritis with Fistulizing Crohn's Disease: A Rare Presentation.
The Journal of the Association of Physicians of IndiaBeyond the Norm: Recognizing Uncommon Presentations of Large Vessel Vasculitis.
The Journal of the Association of Physicians of IndiaIncomplete Susac Syndrome With Recurrent Retinal Occlusions and Vertigo: A Case of Early Immunosuppressive Success.
CureusHybrid Endovascular Repair of Complex Abdominal Aortic Aneurysms in Takayasu Arteritis.
JACC. Case reportsConcomitant Diagnosis and Therapeutic Response of Large-vessel Vasculitis and Hodgkin Lymphoma on 18 F-FDG PET/CT.
Clinical nuclear medicineNavigating complex clinical decisions: kidney transplantation following abdominal aorto-aortic bypass in infantile Takayasu arteritis.
Pediatric nephrology (Berlin, Germany)Comparison of drug retention rates between TNF inhibitors and tocilizumab for Takayasu arteritis: a multicenter retrospective study.
Immunological medicineMacaroni sign and Takayasu arteritis: point-of-care ultrasound utility.
Revista clinica espanolaSecondary amyloidosis as a cause of nephrotic syndrome in Takayasu arteritis.
BMJ case reportsAcute Myocardial Infarction as the First Clinical Presentation of Takayasu Arteritis in a 20-Year-Old Woman.
JACC. Case reportsSevere Diffuse Takayasu Arteritis Manifestation in Childhood.
JACC. Case reportsThe fragility of randomized controlled trials in large vessel vasculitis.
Autoimmunity reviewsA retrospective cohort study of 203 patients with Takayasu arteritis: experience from a Brazilian tertiary center.
Advances in rheumatology (London, England)Novel presentation of Takayasu arteritis in a young girl: severe dystonia, stroke and left ventricular thrombus.
BMJ case reportsPrognostic significance and rationality of regular non-invasive imaging follow-up in Takayasu arteritis: A large multicenter cohort study.
Seminars in arthritis and rheumatismCardiac disease in patients with vasculitis.
Clinical research in cardiology : official journal of the German Cardiac SocietyMycophenolate mofetil plus methotrexate versus cyclophosphamide with sequential azathioprine for treatment of Takayasu arteritis.
Annals of the rheumatic diseasesRenal Artery Involvement in Pediatric-Onset Takayasu Arteritis: Renal Characteristics and Mid-Term Follow-up Outcomes.
Klinische PadiatrieTakayasu Arteritis Following Necrotizing Fasciitis: A Case Report and Brief Review of the Literature.
CureusAcute left heart failure is the initial manifestation of Takayasu arteritis: a case report.
BMC cardiovascular disordersThe use of tumor necrosis factor inhibitors during high-risk pregnancies in antiphospholipid syndrome: a clinical report of a patient with concomitant Takayasu arteritis and case-based review.
ReumatismoEffectiveness of intravenous infliximab versus subcutaneous adalimumab in Takayasu arteritis: a multicentre retrospective study.
Rheumatology (Oxford, England)A rare case of severe bilateral chorioretinal coccidioidomycosis in an immunocompromised pediatric patient with Takayasu Arteritis.
American journal of ophthalmology case reportsHigh ischemic deficit in computed tomography perfusion is a risk factor for cerebral vascular ischemic events in Takayasu arteritis: a prospective observational study.
BMC rheumatologyArteritic Anterior Ischemic Optic Neuropathy in Takayasu Arteritis: An Ominous Systemic Sign?
Journal of ophthalmic & vision researchOptimizing ultrasound evaluation of carotid artery stenosis in Takayasu's Arteritis: a focus on residual inner diameter as a key parameter.
Clinical rheumatologySystematic review and meta-analysis of the importance of pre-pregnancy maternal health on the risk of hypertensive disorders of pregnancy.
Pregnancy hypertensionCognitive impairment and other neuropsychiatric manifestations in patients with primary vasculitis: a systematic review.
Seminars in arthritis and rheumatismStrengthening the Prediction Model for Cardiovascular Events in Takayasu Arteritis: Future Directions and Enhancements.
The Canadian journal of cardiologyTakayasu arteritis masquerading as an isolated sinus of valsalva dissection in a young adult.
Journal of echocardiographyA Rare Case of Takayasu Arteritis Presenting With Syncope and Elevated Inflammatory Markers in an Elderly Male With Learning Disability.
CureusAortic dissection in a patient with Takayasu arteritis accompanied by pericardial effusion and atrioventricular block: A case report.
SAGE open medical case reportsInterventions Related to Takayasu Arteritis, their Clinical and Angiographic Associations, and Prognostic Relevance - A Cohort Study.
Mediterranean journal of rheumatologyA case of concomitant systemic lupus erythematosus and Takayasu arteritis.
Rheumatology advances in practicePredictors of Cardiovascular Events in Patients With Takayasu Arteritis: A Real-World Study.
The Canadian journal of cardiologyAn update on stroke and transient ischemic attack in Takayasu arteritis: A systematic review and meta-analysis.
Joint bone spineNASCI case of the month: "the role of FDG PET-CT in detecting active Takayasu arteritis".
The international journal of cardiovascular imagingNon-Aorto-Ostial Takayasu Arteritis Presenting as Exertional Chest Pain and Syncope Resulting in Coronary Artery Bypass Surgery in a Teenager.
CureusA Well Built Risk Model in Takayasu Arteritis: Strengths Acknowledged, Gaps Remain.
The Canadian journal of cardiologyTakayasu Arteritis on Ultra-Widefield Imaging.
JAMA ophthalmologyDevelopment of Takayasu arteritis during deep molecular response of chronic myeloid leukaemia: a case report and literature review.
Modern rheumatology case reportsTurkish Society for Rheumatology (Turkish Takayasu Arteritis Study Group) recommendations for the diagnosis, follow-up and the treatment of Takayasu's arteritis.
Clinical and experimental rheumatologyChallenging diagnosis of chronic myelomonocytic leukemia (CMML) in a patient with Takayasu arteritis: case report.
Leukemia & lymphomaEchocardiographic evaluation of Takayasu arteritis including speckled tracking echocardiography and aortic stiffness.
Indian heart journalTransseptal Guidewire Stabilization to Facilitate Endograft Delivery During Thoracic Endovascular Aortic Repair of a Giant Tortuous Thoracic Aortic Aneurysm.
JACC. Case reportsValidation and clinical application of 2022 ACR/EULAR criteria for Takayasu arteritis in a large Chinese cohort.
Rheumatology (Oxford, England)Case Report: Can early full-course tocilizumab therapy reverse vascular stenosis in Takayasu arteritis?
Frontiers in immunologySupra-aortic Percutaneous Interventions in Takayasu Arteritis: Time to Liberalise Indications.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular SurgeryBeyond Atherosclerosis: Takayasu Arteritis Presenting as Ischemic Stroke in a Young Patient With Significant Traditional Vascular Risk Factors.
CureusUpper extremity function and strength, assessed with unsupported upper limb exercise test, is impaired in patients with Takayasu arteritis.
Modern rheumatologyTakayasu arteritis with a ruptured intracranial aneurysm in a pediatric patient: illustrative case.
Journal of neurosurgery. Case lessonsImaging features of Takayasu arteritis in a young male.
European heart journal. Imaging methods and practiceAsymptomatic hypertension and bilateral renal artery stenosis in Takayasu arteritis.
ACR open rheumatologyComplete obliteration of abdominal aorta with collateral circulation in Takayasu arteritis.
Clinical rheumatologyComplex Presentation of Takayasu Arteritis in a Young Female: A Diagnostic Dilemma.
JACC. Case reportsWhen the Vessels Whisper: The Power of Multimodality Imaging in Takayasu Arteritis.
JACC. Case reportsEndovascular Therapy for Supra-aortic Artery Stenosis Caused by Takayasu's Arteritis: Long Term Results.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular SurgeryCollateral Rescue, Arterial Burden: Untreated Takayasu Arteritis and its Long-Term Complications.
Mediterranean journal of rheumatologyElevated soluble CD226 in Takayasu arteritis is useful for differentiation from giant cell arteritis, disease activity assessment, and prognosis prediction.
MedicineUnveiling the silent echoes: Multiple sinus of valsalva aneurysms as a rare cardiac imprint of Takayasu arteritis depicted on CT angiography.
Journal of cardiovascular computed tomographyHepatovascular manifestation of Takayasu arteritis presenting as sudden cardiac death.
Journal of forensic and legal medicineA 50-Year Delay in the Diagnosis of Takayasu Arteritis: Clinical Presentation and Therapeutic Insights.
CureusTakayasu's Arteritis with Systemic Lupus Erythematosus: A Case Report.
Clinical Medicine Insights. CardiologyA Systematic Review of Anti-TNF and Anti-IL-6 Treatments for Pediatric Takayasu Arteritis: Addressing a Therapeutic Dilemma.
Paediatric drugsCardiac Insights in Takayasu's Arteritis: Echocardiographic Differences in Active Takayasu Arteritis.
Echocardiography (Mount Kisco, N.Y.)Coronary Ostial Angioplasty for Takayasu Arteritis Using External Iliac Artery Graft: 1-year Follow-up.
Annals of thoracic surgery short reportsCerebral Perfusion Features in Takayasu Arteritis: Insights From pCASL MRI.
International journal of rheumatic diseasesMedian arcuate ligament syndrome (MALS) in a patient with Takayasu Arteritis.
Medicina clinicaMacaroni Sign: Point-of-Care Ultrasound Identification of Takayasu Arteritis.
The American journal of medicineAssociações
Organizações que acompanham esta doença — pra ter apoio e orientação
Ainda não temos associações cadastradas para Arterite de Takayasu.
É de uma associação que acompanha esta doença? Fale com a gente →
Comunidades
Grupos ativos de quem convive com esta doença aqui no Raras
Ainda não existe comunidade no Raras para Arterite de Takayasu
Pacientes, familiares e cuidadores se organizam em comunidades pra compartilhar experiências, fazer perguntas e se apoiar. Você pode ser o primeiro.
Tire suas dúvidas
Perguntas, dicas e experiências compartilhadas aqui na página
Participe da discussão
Faça login para postar dúvidas, compartilhar experiências e interagir com especialistas.
Fazer loginDoenças relacionadas
Doenças com sintomas parecidos — ajudam quem ainda está buscando diagnóstico
Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Systematic Review and Meta-Analysis for JCS 2026 Guideline on Management of Large-Vessel Vasculitis.Circulation journal : official journal of the Japanese Circulation Society· 2026· PMID 41692437mais citado
- Pregnancy complicated by Takayasu arteritis and recurrent pregnancy loss.
- Current and Future Treatments for Takayasu Arteritis: Toward Cardiovascular Risk Modification.
- [Analysis of follow-up and prognosis in pediatric rheumatic diseases associated with pulmonary embolism].
- JCS 2026 Guideline on Management of Large Vessel Vasculitis.Circulation journal : official journal of the Japanese Circulation Society· 2026· PMID 41866178mais citado
- [Pathomorphological features of various etiological forms of aortic aneurysm].
- A Silent Vasculitis With a Loud Presentation: Takayasu Arteritis Causing Intracerebral Hemorrhage.
- Carotid steal syndrome with recurrent syncope: A novel manifestation of Takayasu arteritis.
- Burned out Takayasu arteritis in a young caucasian female: A rare case of aortic regurgitation and aneurysm requiring surgical repair.
- Metabolic-Epigenetic Crosstalk in Takayasu Arteritis: The ANK2-MAVS-IL-8 Axis as a Novel Therapeutic Paradigm.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:3287(Orphanet)
- OMIM OMIM:207600(OMIM)
- MONDO:0017991(MONDO)
- GARD:7730(GARD (NIH))
- Variantes catalogadas(ClinVar)
- Busca completa no PubMed(PubMed)
- Artigo Wikipedia(Wikipedia)
- Q432462(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
