Raras
Buscar doenças, sintomas, genes...
Chikungunya
ORPHA:324625CID-10 · A92.0CID-11 · 1D40DOENÇA RARA

Infecção causada pelo vírus Chikungunya, transmitido por mosquitos; é caracterizada por febre e artralgia grave.

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Introdução

O que você precisa saber de cara

📋

Infecção causada pelo vírus Chikungunya, transmitido por mosquitos; é caracterizada por febre e artralgia grave.

Pesquisas ativas
21 ensaios
92 total registrados no ClinicalTrials.gov
Publicações científicas
9.079 artigos
Último publicado: 2026 Apr 15

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
Unknown
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
0.0
Worldwide
Início
All ages
🏥
SUS: Sem cobertura SUSScore: 0%
CID-10: A92.0
Você se identifica com essa condição?
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Entender a doença

Do básico ao detalhe, leia no seu ritmo

Preparando trilha educativa...

Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🧬
Pele e cabelo
6 sintomas
🩸
Sangue
5 sintomas
🦴
Ossos e articulações
5 sintomas
🧠
Neurológico
4 sintomas
🫃
Digestivo
2 sintomas
👁️
Olhos
2 sintomas

+ 24 sintomas em outras categorias

Características mais comuns

90%prev.
Febre
Muito frequente (99-80%)
90%prev.
Artralgia
Muito frequente (99-80%)
90%prev.
Fadiga
Muito frequente (99-80%)
55%prev.
Artrite
Frequente (79-30%)
55%prev.
Motivação diminuída
Frequente (79-30%)
55%prev.
Erupção cutânea
Frequente (79-30%)
51sintomas
Muito frequente (3)
Frequente (15)
Ocasional (24)
Muito raro (9)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 51 características clínicas mais associadas, ordenadas por frequência.

FebreFever
Muito frequente (99-80%)90%
ArtralgiaArthralgia
Muito frequente (99-80%)90%
FadigaFatigue
Muito frequente (99-80%)90%
ArtriteArthritis
Frequente (79-30%)55%
Motivação diminuídaDiminished motivation
Frequente (79-30%)55%

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico9.079PubMed
Últimos 10 anos200publicações
Pico2026174 papers
Linha do tempo
2026Hoje · 2026🧪 2006Primeiro ensaio clínico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
Aprovado1
3Fase 35
1Fase 11
·Pré-clínico13
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 20 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Chikungunya

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

🟢 Recrutando agora

9 pesquisas recrutando participantes. Converse com seu médico sobre a possibilidade de participar.

Outros ensaios clínicos

92 ensaios clínicos encontrados, 21 ativos.

Distribuição por fase
Ver todos no ClinicalTrials.gov
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Publicações mais relevantes

Timeline de publicações
7.181 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 7.181

#1

In-utero exposure to chikungunya and child morbimortality: a population-based study using linked routine data.

Nature communications2026 Mar 21

Este estudo com crianças brasileiras revela que a exposição à Chikungunya durante a gravidez aumenta significativamente o risco de hospitalização nos primeiros três anos de vida, com 37 internações extras a cada 1000 crianças expostas. Médicos e futuros pais devem estar cientes de que o risco é especialmente alto se a exposição ocorrer próximo ao parto (quase dobrando a chance), e embora não tenha havido um aumento expressivo no risco de morte, é crucial um acompanhamento atento da saúde dessas crianças.

🇧🇷 traduzido
#2

A disease-agnostic approach to ensemble learning for infectious disease forecasting.

Nature communications2026 Mar 20

Um novo método de previsão, chamado epiFFORMA, foi desenvolvido para prever surtos de doenças infecciosas como a Chikungunya de forma mais precisa. A grande inovação é que ele não depende de um histórico de dados extenso de uma doença específica, sendo ideal para antecipar surtos de doenças emergentes ou com pouca informação. Isso permite que médicos e autoridades de saúde pública planejem intervenções mais rápidas e eficazes, como campanhas de vacinação ou controle de vetores, protegendo melhor os pacientes e reduzindo a morbidade e mortalidade.

🇧🇷 traduzido
#3

Characterization of arbovirus infections in patients within Haiti by screening discarded malaria rapid diagnostic test cassettes.

PLoS neglected tropical diseases2026 Mar

Em meio à instabilidade no Haiti, este estudo utilizou uma abordagem inovadora, analisando testes rápidos de malária descartados para monitorar arbovírus. A principal descoberta, crucial para médicos e pacientes, foi a detecção **exclusiva do vírus Dengue tipo 3 (DENV-3)** entre 2021 e 2023, principalmente em 2023, alertando para a prevalência desta doença na região. É importante notar que **não foram encontrados casos de Chikungunya** ou de Oropouche, apesar da busca por esses vírus, demonstrando a utilidade da metodologia para vigilância de ameaças virais em contextos desafiadores.

🇧🇷 traduzido
#4

The SMARCA4-TMEM47 axis plays an essential role in chikungunya virus RNA replication.

Proceedings of the National Academy of Sciences of the United States of America2026 Mar 24

Este estudo revelou um mecanismo crucial para a replicação do vírus Chikungunya no corpo, envolvendo as proteínas SMARCA4 e TMEM47. Os pesquisadores descobriram que, ao interferir com essa via, a replicação viral é significativamente reduzida, diminuindo a carga viral e os danos causados pela doença. Isso indica que a interação entre SMARCA4 e TMEM47 representa um alvo promissor para o desenvolvimento de novos medicamentos eficazes contra a Chikungunya.

🇧🇷 traduzido
#5

Noise and neglect: Social-media signals expose attention gaps for dengue, chikungunya, lymphatic filariasis and kala-azar in India's vector-borne NTDs.

PLoS neglected tropical diseases2026 Mar

Este estudo sobre a discussão online de dengue, chikungunya, filariose e calazar na Índia revela que a atenção digital nem sempre corresponde à real carga epidemiológica dessas doenças. Enquanto a dengue gera muita discussão e a filariose tem atenção desproporcional online, o calazar, uma doença grave, é quase ignorado digitalmente, apesar dos temas de prevenção e tratamento serem relevantes. Para pacientes e médicos, isso aponta para a necessidade urgente de campanhas de saúde pública mais estratégicas e personalizadas, focadas em informações precisas e na prevenção, para preencher lacunas de conhecimento e garantir que mensagens cruciais cheguem à população.

🇧🇷 traduzido

Publicações recentes

Ver todas no PubMed

📚 EuropePMC5.204 artigos no totalmostrando 198

2026

Clinical characteristics and mortality of critically ill patients with chikungunya infection: a multicenter study in Paraguay.

BMC infectious diseases
2026

Phosphorothioate Modification-Regulated One-Pot CRISPR Assay for Arbovirus Detection.

ACS infectious diseases
2026

Molecular detection and epidemiological characterization of dengue and malaria coinfection in the Guiriko region, Burkina Faso.

Acta tropica
2026

In-utero exposure to chikungunya and child morbimortality: a population-based study using linked routine data.

Nature communications
2026

Towards national guidance on dengue and chikungunya vaccination in travellers: Lessons from global recommendations.

Travel medicine and infectious disease
2026

Post-marketing safety evaluation of the live-attenuated chikungunya vaccine (IXCHIQ).

Vaccine
2026

A disease-agnostic approach to ensemble learning for infectious disease forecasting.

Nature communications
2026

Characterization of arbovirus infections in patients within Haiti by screening discarded malaria rapid diagnostic test cassettes.

PLoS neglected tropical diseases
2026

Chikungunya Virus in 2025: Epidemiology, Immunopathogenesis, and Vaccine Development - A Narrative Review.

Infection and drug resistance
2026

Diagnostic and genomic characterization of an imported chikungunya virus case in Ningxia Hui Autonomous Region, China, September 2025.

Infectious medicine
2026

Chronic phase of Chikungunya: understanding the impact of joint pain using data science and artificial intelligence.

Tropical medicine and health
2026

A chikungunya virus-like particle vaccine reduces chikungunya disease in cynomolgus macaques and protection is mediated by antibody transferred from vaccinated humans.

NPJ vaccines
2026

Bridging the gap: ex vivo human skin explants for mechanistic studies of arboviruses.

Current opinion in virology
2026

Differential expression of miRNAs in Vero cells after Mayaro virus infection.

Memorias do Instituto Oswaldo Cruz
2026

The SMARCA4-TMEM47 axis plays an essential role in chikungunya virus RNA replication.

Proceedings of the National Academy of Sciences of the United States of America
2026

Noise and neglect: Social-media signals expose attention gaps for dengue, chikungunya, lymphatic filariasis and kala-azar in India's vector-borne NTDs.

PLoS neglected tropical diseases
2026

Social Mixing Patterns and Chikungunya Reemergence Risk in French Polynesia.

JAMA network open
2026

High burden of autochthonous arboviral infections during the summer season in Verona province, Italy, during 2025.

The Journal of infection
2026

Chikungunya viral load in cerebrospinal fluid and blood is not associated with severity of neurological manifestations in children.

PLoS neglected tropical diseases
2026

Out-of-Pocket Costs of Chikungunya in Travelers: The 2022-2023 Paraguay Outbreak.

Journal of travel medicine
2026

Adverse Pregnancy Outcomes and Prevalence Associated With Arboviral Infections (Zika, Dengue, and Chikungunya): An Umbrella Review of Systematic Reviews and Meta-Analyses.

Reviews in medical virology
2026

Engineering the ADDomer Nanoparticle Vaccine Scaffold for Improved Assembly and Enhanced Stability.

ACS synthetic biology
2026

Seroprevalence and preventive practices of dengue and chikungunya among school children in Bangkok: Gaps in prevention and vaccination strategies.

PLoS neglected tropical diseases
2026

Chikungunya Virus (CHIKV) Pathogenesis: From Acute Fever to Chronic Arthritis-Immune Mechanisms and Therapeutic Implications.

Current topics in medicinal chemistry
2026

A mathematical approach to Chikungunya transmission dynamics incorporating media awareness and optimal control.

Scientific reports
2026

Control and mitigation of dengue and Zika virus transmission in a hospital in Recife, Brazil: a successful experience with an integrated control program against Aedes aegypti.

Parasites &amp; vectors
2026

Severe chikungunya infection in a returned traveler from Sri Lanka to Australia.

Travel medicine and infectious disease
2026

Symptom overlap in chikungunya and dengue: A diagnostic challenge during outbreaks.

Acta tropica
2026

Re-emergence of chikungunya virus in the Caribbean: travel-associated cases imported from Cuba to France, 2025.

Journal of travel medicine
2026

Detection of novel Wolbachia strains in Aedes aegypti populations from a recent arbovirus outbreak region in Pune District, Maharashtra, India (2024).

Frontiers in microbiology
2026

Screening assay to monitor mono-ADP-ribosylhydrolase activity of viral macrodomains in cells.

Communications biology
2026

A Study on Prevalence of Malarial Retinopathy among Malaria Cases and to Determine Its Presence as a Marker of Severe Malaria: Observations from Eastern India.

The Journal of the Association of Physicians of India
2026

Clinical and Laboratory Profile of Patients with Tropical Coinfections Admitted at a Tertiary Care Center in North India.

The Journal of the Association of Physicians of India
2026

Differential Expression of Defensins and Other Innate Immune Effectors by Indian Isolates of Chikungunya Virus.

Journal of medical virology
2026

Spatiotemporal Dynamics and Reemergence of Chikungunya Virus in Bangladesh from 2008 to 2025.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2026

Dose-dependent immune modulation in arboviral coinfections among febrile patients.

Frontiers in cellular and infection microbiology
2026

Cutaneous Manifestations in Chikungunya- A Systematic Review and Meta-analysis.

Journal of vector borne diseases
2026

Chloride complexes [RuII(N-N)(tpy)Cl]+ coordinated to diimine ligand: Kinetic insights into DNA affinity and biological activity.

Journal of inorganic biochemistry
2026

The Role of Non-covalent Interactions in the Molecular Recognition and Attachment of the Chikungunya Virus to the MXRA8 Receptor.

Chembiochem : a European journal of chemical biology
2026

Mitochondrial COI gene based population genetic structure and diversity of Aedes aegypti populations across diverse climatic regions of India.

Acta tropica
2026

Magnetic SERS-based lateral flow immunoassay for ultrasensitive on-site detection of Chikungunya virus in mosquito vectors.

Mikrochimica acta
2026

Glutamine antagonist DON attenuates chikungunya virus-induced myositis by suppressing inflammatory activation in a murine model.

Emerging microbes &amp; infections
2026

Hidden burden of primary Epstein-Barr virus (EBV) infection in pediatric febrile illness (0-12 years) - A retrospective study.

Journal of postgraduate medicine
2025

[Risk of emergence of mosquito-borne arboviral diseases in Morocco: literature review].

Medecine tropicale et sante internationale
2025

[Mosquito-borne diseases in the Republic of Djibouti: a review of the literature].

Medecine tropicale et sante internationale
2026

Chikungunya in Military Health System Beneficiaries, 2020-2024.

MSMR
2026

Arboviral antibody biomarkers and fetomaternal outcomes in pregnant women with and without HIV across Nigeria: A multi-regional cross-sectional study.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2026

[Between the unknown and the emerging: mapping the Oropouche and Mayaro viruses in Brazil].

Cadernos de saude publica
2026

Pathogenesis of chikungunya arthritis: A scoping review.

PLOS global public health
2026

Aedes aegypti Hsp70 has enhanced ATPase and protein protection under oxidative stress.

International journal of biological macromolecules
2026

Artificial light at night as a potential driver of Aedes aegypti establishment in arid cities: insights from Las Vegas.

Journal of medical entomology
2026

Bloodmeal metabarcoding reveals host feeding patterns for Aedes aegypti and Culex quinquefasciatus in Jutiapa, Guatemala and Texas, USA.

Research square
2026

Single-Cell Sequencing Reveals the Immune Characteristics of Secondary Liver Injury Induced Indirectly by CHIKV Infection in Rhesus Macaques.

Viruses
2026

Increased Mortality Rates During the 2025 Chikungunya Epidemic in Réunion Island.

Viruses
2026

Next-Generation HIV-1 Therapeutics in Co-Endemic Settings.

Biomedicines
2026

mRNA-Encoded Antibodies: An Emerging Paradigm in Antiviral Protection.

Biomolecules
2026

Mesenchymal stem cells-derived TGF-β1 promotes polarization of M2 macrophages in mice with acute-on-chronic liver failure via FOSL1/MERTK axis.

Stem cell research &amp; therapy
2026

Comparative Analysis of Next- and Third-Generation Sequencing Platforms for Chikungunya Virus Whole-Genome Sequencing Using a Lineage-Inclusive Primer Set During the 2025 Foshan Outbreak.

Tropical medicine and infectious disease
2026

AI-Assisted Differentiation of Dengue and Chikungunya Using Big, Imbalanced Epidemiological Data.

Tropical medicine and infectious disease
2026

Venezuelan Equine Encephalitis Virus Antagonizes the cGAS-STING Pathway.

Cells
2026

Vertically infected Aedes aegypti excrete infectious arboviruses in saliva.

BMC biology
2026

Cytokine-based rapid process control of live virus production: MCP-1 as a cross-family biomarker in Vero cells.

Journal of virological methods
2026

Development of a nucleotide prodrug of 4'-fluorouridine to improve tolerability.

European journal of medicinal chemistry
2026

Unveiling the Molecular Profile and Antiviral Potential of Costus arabicus L. Against Zika Virus.

Chemistry &amp; biodiversity
2025

Visualized analysis of core themes and emerging frontiers in global chikungunya virus studies.

Frontiers in microbiology
2026

Beyond Chikungunya: Hidden risks of anti-mosquito chemicals.

Eco-Environment &amp; Health
2026

Crossover Evaluation of Two Ambient AI Scribe Tools in the Emergency Department.

Applied clinical informatics
2026

Travel-Related Challenges of Chikungunya Virus and Vaccination Options.

Journal of epidemiology and global health
2026

Resurgent threat in a changing climate: A 20-year bibliometric analysis of global Chikungunya research evolution and pandemic preparedness.

PLoS neglected tropical diseases
2026

Integrated In Silico, In Vivo, and Deep Learning Approaches in the Discovery of Novel Candidate Molecules for Aedes aegypti Control.

Archives of insect biochemistry and physiology
2026

A systematic review and meta-analysis of mosquito arboviral infections detected through xenosurveillance in Africa: A focus on West Nile, Rift Valley fever, and chikungunya virus infections.

Current research in parasitology &amp; vector-borne diseases
2026

Metagenomic surveillance of undiagnosed febrile illness in Nigeria does not reveal the etiological agent for most patients.

bioRxiv : the preprint server for biology
2026

Natural infection of Aedes albopictus with the wAlbB strain and Ae. aegypti with the wPip strain of Wolbachia in Iran.

Scientific reports
2026

Sterile insect technique for suppression of endemic Aedes albopictus in urban Reunion Island: A pilot trial of technical feasibility and entomological impact.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2026

Overview of Chikungunya Virus Pathogenesis, Genome Variation, Epidemiology, and Control.

Virus research
2026

Epstein-Barr Virus-positive Diffuse Large B-cell Lymphoma Presenting as Pyrexia of Unknown Origin Complicated by Paraneoplastic Neurological Syndrome.

Annals of African medicine
2026

Entomological investigation of the 2023 chikungunya outbreak in Pouytenga, Burkina Faso, highlights the virus circulation in Aedes aegypti.

Current research in parasitology &amp; vector-borne diseases
2026

(Sero)prevalence of (re)emerging major arbovirus infections in Africa: a systematic review and meta-analysis protocol.

Systematic reviews
2026

Tolerance to persistent cell-fusing agent virus infection in Aedes aegypti mosquitoes correlates with maintenance of lipid reserves.

BMC biology
2026

Application of CRISPR-Cas12a/Cas13a dual enzyme cleavage technology in the differential diagnosis of Chikungunya virus and Dengue virus.

Journal of biological engineering
2026

Investigation of chikungunya arbovirus in cities of Bushehr province: An ELISA-based cross-sectional study.

Virus research
2026

Novel therapeutic topical gel approach for chronic inflammation and pain management in osteo- and viral-arthritis.

Biomedicine &amp; pharmacotherapy = Biomedecine &amp; pharmacotherapie
2026

Co-circulation of Plasmodium vivax and Arboviruses in the Brazil-French Guiana Border.

Revista da Sociedade Brasileira de Medicina Tropical
2026

Clinical Features and Factors Associated with Disease Severity in Acute Chikungunya Fever: A Retrospective Analysis.

Infection and drug resistance
2026

Chikungunya clinical management guidance: insights from a health system stakeholder study in Indonesia.

BMJ global health
2025

An integrated surveillance in Zhejiang Province: ecological and pathogen survey of vectors and reservoir hosts in 2024.

Frontiers in veterinary science
2026

Socioeconomic and household water management determinants of malaria and other vector-borne disease prevention in Urban Gujarat, India.

Malaria journal
2026

Temperature-sensitive incubation, transmissibility and risk of Aedes albopictus-borne chikungunya virus in Europe.

Journal of the Royal Society, Interface
2026

AGPAT1 is a novel Chikungunya virus receptor on human cells.

Journal of virology
2026

Reverse vaccinology-based design of a universal multiepitope vaccine against chikungunya virus: Phylogenetic and immunoinformatics approaches.

Scientific reports
2026

Chikungunya virus-induced persistent allodynia is accompanied by joint microenvironmental changes and involves cartilage degradation and TRPA1 activation.

British journal of pharmacology
2026

Temephos susceptibility status in Aedes aegypti populations from western, central, and eastern regions of Cuba.

Parasites &amp; vectors
2026

Water physicochemical parameters linked to mosquito diversity and arbovirus infection in Mexico City.

Acta tropica
2026

Natural Alkaloids as Antiviral Agents Against RNA Viruses: A Comprehensive and Mechanistic Review.

Molecules (Basel, Switzerland)
2026

Trans-stadial midgut development in Aedes aegypti L. (Diptera: Culicidae) is long-term impaired by sublethal concentrations of Schinus terebinthifolia Raddi (Anacardiaceae) leaf preparations.

Experimental parasitology
2026

New progress in the global expansion and prevention of chikungunya fever.

Acta tropica
2026

Global and regional burden of chikungunya from 2004 to 2024: a worldwide observational study.

Journal of global health
2026

Reported circulation of Zika and re-circulation of Chikungunya in Dengue-endemic Dhaka, Bangladesh in 2024.

PloS one
2026

Chikungunya outbreak in eastern Senegal, 2023.

BMC infectious diseases
2026

Distribution of Aedes aegypti and Aedes albopictus, and the current situation of dengue fever and chikungunya in Iran and neighboring countries: a review study.

PLoS neglected tropical diseases
2026

Phytol from Sphaeranthus indicus: A Natural Insecticide Against Aedes aegypti and Culex quinquefasciatus.

Acta parasitologica
2026

Entomovirological Surveillance in Aedes (Stegomyia) aegypti Linnaeus, 1762 and Aedes (Stegomyia) albopictus Skuse, 1894 (Diptera, Culicidae) in new housing areas in eastern Maranhão, Brazil.

Brazilian journal of biology = Revista brasleira de biologia
2026

Investigation of a clinical trial drug VV261 as a potent antiviral candidate against Chikungunya virus.

Signal transduction and targeted therapy
2026

Mayaro Virus Infections in European Field Researchers in the Remote Amazon Rainforest, French Guiana, 2024.

The American journal of tropical medicine and hygiene
2026

Changing trends of vector-borne diseases after the COVID-19 pandemic in India.

Journal of infection in developing countries
2026

Emerging local chikungunya virus transmission in a major urban area in Southern China: characteristics of clinical manifestations, viral evolution and climatic influences.

National science review
2026

Clinical epidemiology and viral genomics insights from a Chikungunya fever outbreak in South China, 2025.

Frontiers in cellular and infection microbiology
2026

A brief review of chikungunya fever: From molecular virology to countermeasures.

Infectious medicine
2026

Chikungunya fever: a re-emerging mosquito-borne threat demanding proactive prevention strategies in Asia.

Frontiers in public health
2026

Arbovirus Outbreak Reveals Co-Infection of Dengue and Chikungunya Viruses at Zona da Mata Region in Minas Gerais, Brazil, During 2024.

Tropical medicine &amp; international health : TM &amp; IH
2026

Harnessing insect-derived oils for enhanced efficacy of plant-based repellents against disease-transmitting mosquitoes.

Scientific reports
2026

Technical validation and implementation of a multiplex real-time PCR for differential diagnostic detection of Zika virus, yellow fever virus, dengue virus and chikungunya virus (ZYDC-PCR).

BMC infectious diseases
2026

Live-attenuated chikungunya vaccine in children: a randomized phase 2 trial.

Nature medicine
2026

Chikungunya seroprevalence in the Horn of Africa: A systematic review and meta-analysis.

Medicine
2026

CRISPR-Cas13a-Powered Electrochemical Biosensor for Label-Free Detection of Chikungunya Virus RNA Using a Ceria-Modified Screen-Printed Carbon Electrode.

ACS sensors
2026

Molecular detection of insecticide resistance markers in Aedes aegypti (Diptera: Culicidae) populations from Haiti.

Journal of medical entomology
2025

Review of selected mosquito-borne diseases: arboviruses (dengue, chikungunya, Zika, West Nile, Japanese encephalitis, yellow fever) and parasitic diseases (malaria, lymphatic Filariasis).

Frontiers in public health
2026

Global epidemiology and evolutionary dynamics of arboviruses: A systematic review of surveillance, control strategies, and emerging threats.

Dialogues in health
2025

Prioritizing climate-sensitive zoonotic diseases in Bangladesh: integrating climate hazards, pathogen transmissibility and potential health outcomes.

The journal of climate change and health
2026

Cutaneous Chikungunya in a Nonfebrile Traveler to Madagascar.

The American journal of tropical medicine and hygiene
2026

Development and validation of a sample-to-result real time multiplex RT-PCR test for human African trypanosomiasis and arboviral febrile illnesses in the Democratic Republic of the Congo.

BMC infectious diseases
2026

Bioengineered chimeric VLPs targeting chikungunya virus and SARS-CoV-2 show high immunogenicity in mice.

Biochemical and biophysical research communications
2026

Side effects dim hopes for first chikungunya vaccine.

Science (New York, N.Y.)
2026

Decoding the Human Kinases of Chikungunya Viral Proteins.

Vector borne and zoonotic diseases (Larchmont, N.Y.)
2025

Chikungunya outbreak in Guangdong Province, China, 2025.

Infectious medicine
2026

Aedes albopictus CYP6Z8 metabolizes multiple AChE-inhibiting insecticides.

Pesticide biochemistry and physiology
2026

The effect of stage-specific heatwaves on Aedes albopictus (Diptera: Culicidae) survival and development.

Journal of medical entomology
2026

Optimizing health care delivery by adapting diagnostics in a low-resource setting: The case of San Miguel Hospital, Sucumbíos, Ecuador.

New microbes and new infections
2025

The impact of variations in the chikungunya genome on the clinical manifestations and transmission of the disease.

Journal of family medicine and primary care
2026

A Systematic Review and Meta-Analysis of Global DENV, CHIKV, and ZIKV Co-Infection.

Reviews in medical virology
2026

Chikungunya virus E1 fusion loop-membrane interaction: Conserved residues and shallow insertion.

Biophysical journal
2026

Entomo-virological investigation in urban forest fragments and intradomiciles during a dengue outbreak in Salinas, MG, Brazil.

Memorias do Instituto Oswaldo Cruz
2026

Travel Health Risks in Adults Over 60 Years of Age: Insights from the +Redivi Network in Spain.

Journal of travel medicine
2026

Strengthening Arboviral Epidemic Response Through Entomological Surveillance: Insights from Bobo-Dioulasso, Burkina Faso.

Current issues in molecular biology
2026

Kinetic Traps in RNA Folding: Targeted Design of Frameshifting Element Mutants by Thermodynamic and Kinetic Analysis of the Chikungunya Virus.

The journal of physical chemistry. B
2025

Knowledge, attitudes, and practices regarding chikungunya fever among healthcare workers: a cross-sectional study in Sichuan Province, China.

Frontiers in public health
2026

Intrahost population dynamics of chikungunya virus in humans and naturally infected Aedes mosquitoes reveal transmission-driven diversity.

Virus evolution
2026

Thermal stress responses on developmental time, survival, and wing morphometrics in desert and coastal strains of Aedes aegypti (Diptera: Culicidae) from India.

Acta tropica
2026

Human autoantibodies against type I interferons in severe viral disease.

Current opinion in virology
2026

The ability of alphavirus replicases to synthesize non-viral type I interferon-inducing RNAs correlates with viral RNA synthesis and has a diverse impact on virus replication and pathogenicity.

Journal of virology
2026

Factors associated with hospitalization and deaths of chikungunya patients in Brazil from 2017 to 2023.

Transactions of the Royal Society of Tropical Medicine and Hygiene
2026

Chikungunya in 2025: Comprehensive Insights into Virology, Diagnostics, Vaccines, and Antiviral Therapies.

Viruses
2025

Preparing for the Next Potential Pandemic-Chikungunya, Dengue, Zika and Other Viruses.

Viruses
2026

Temporal and Geographical Patterns of Pacific Arboviral Vectors on Ebeye, Republic of the Marshall Islands: Insights from a Longitudinal Entomological Study.

Pathogens (Basel, Switzerland)
2025

Seroprevalence of Dengue, Chikungunya, and Zika Viruses Among Febrile Patients in Dhaka, Bangladesh: A Hospital-Based Cross-Sectional Study.

Pathogens (Basel, Switzerland)
2026

Triple-Olfactory Mechanism Synergy: Development of a Long-Lasting DEET-Botanical Composite Repellent Against Aedes albopictus.

Insects
2026

Phylogeographic Insights into Aedes albopictus in Korea: Integrating COX1, ND5, and CYTB Analyses.

Insects
2025

Leveraging Climate Data Through Intelligent Systems for the Prediction of Arbovirus Transmission by Aedes aegypti.

International journal of environmental research and public health
2026

Proof-of-Concept Machine Learning Framework for Arboviral Disease Classification Using Literature-Derived Synthetic Data: Methodological Development Preceding Clinical Validation.

Healthcare (Basel, Switzerland)
2026

Occupational Infection Prevention Among Nurses and Laboratory Technicians Amidst Multiple Health Emergencies in Outbreak-Prone Country, D.R. Congo.

Tropical medicine and infectious disease
2026

Cutaneous Manifestations of Emerging Arbovirus Infections Including West Nile, Dengue, Zika, Chikungunya, Usutu, and Toscana Viruses: A Clinical Overview for Dermatologists.

American journal of clinical dermatology
2026

A broadly applicable split-luciferase biosensor approach for rapid antibody detection in emerging infectious diseases.

Applied microbiology and biotechnology
2026

In silico evaluation of bioactive compounds from the sea urchin Temnopleurus toreumaticus: Potential multifunctional agents against mosquito vectors and tropical pathogens.

PloS one
2026

Silymarin Attenuates Arthritis and Myositis in a Murine Model of Acute Infection by Chikungunya and Mayaro Viruses.

ACS infectious diseases
2025

Gut microbe-derived short-chain fatty acids regulate joint inflammation and activation of infiltrating and resident myeloid cells after alphavirus infection.

bioRxiv : the preprint server for biology
2026

Dry Eye Disease After Ocular or Systemic Infection: A Systematic Review.

Eye &amp; contact lens
2026

Discovery of BPR2-D2 compound in inhibiting Chikungunya viral RNA synthesis by replicon systems.

Biomedical journal
2026

Type I IFN autoantibodies underlie chikungunya live-attenuated vaccine encephalitis.

Proceedings of the National Academy of Sciences of the United States of America
2026

Development of a PCB-based electrochemical aptasensor for Chikungunya virus protein detection.

The Analyst
2026

Distinguishing Leptospirosis from Other Causes of Acute Encephalitis Syndrome: Clinical Insights.

Annals of African medicine
2025

Hyperferritinemia Drives Risk: Unravelling the Association Between Ferritin Levels and Multi-Organ Dysfunction in Acute Febrile Illness: An Emergency Medicine Perspective.

Cureus
2025

Predicting the ecological niches of Aedes aegypti s.l. using maximum entropy in Kenya.

Frontiers in tropical diseases
2026

Vaccination against chikungunya - a systematic review on the immunogenicity, tolerability, and safety of the live-attenuated vaccine (LAV) Ixchiq and the virus like particle (VLP) vaccine Vimkunya.

Vaccine
2026

Adjuvant-free biopolymer particles mimicking the Chikungunya virus surface induce protective immunity.

Biomaterials
2026

From pandemic influenza to novel coronaviruses: emerging infectious diseases of the 21st century.

Diagnostic microbiology and infectious disease
2026

Epidemiological and digital syndromic surveillance data on dengue, chikungunya, and SARI in Brazil.

Scientific data
2025

A Point-of-Care Platform for Simultaneous Triplex PCR Detection of Chikungunya, Dengue, and Zika Virus Infections.

Journal of visualized experiments : JoVE
2026

Development of a high-performance synthetic promoter for plant-based bioproduction.

Planta
2025

Surge of Chikungunya Cases in Central India, Post-COVID-19 Pandemic.

Infectious diseases &amp; clinical microbiology
2025

Phenol and chromone compounds for in silico inhibition of nsP2 and nsP3 of Chikungunya virus.

Pharmaceutical science advances
2026

Temporal cytokine profiling of acute dengue, Zika, Chikungunya, and Mayaro virus infections in Northern Peru.

BMC infectious diseases
2026

Unravelling the epidemiological and dispersal dynamics of the 2024-2025 chikungunya virus outbreak on Réunion island.

medRxiv : the preprint server for health sciences
2025

Advances and perspectives for animal models of chikungunya virus infection.

Biosafety and health
2025

Chikungunya virus: Current situation and future challenges.

Biosafety and health
2026

Surveillance-based insights into mosquito-borne disease trends: Implications for public health in Poland and Europe (2018-2024).

Travel medicine and infectious disease
2026

Impact of mutations affecting 4'-fluorouridine susceptibility on fitness and treatment outcomes for Venezuelan equine encephalitis virus.

Journal of virology
2026

Chikungunya: global epidemiology, clinical spectrum, and vector control-lessons for China from the 2025 Guangdong outbreak.

Archives of toxicology
2026

Systematic review of Aedes aegypti control trials suggests publication bias related to author disclosure of conflicts of interest.

PLoS neglected tropical diseases
2026

Modulating Chikungunya and Mayaro virus-induced disease severity in mice using low concentrations of anti-IFNAR1 antibodies.

Emerging microbes &amp; infections
2026

Symptomatic chikungunya and chronic post-infection arthralgia in a highly endemic setting in Northeastern Brazil, 2018-2019: Clinical characteristics, prevalence and associated factors.

PloS one
2026

Defining Viro-Osteopathology: Unresolved Mechanistic Questions in the Pathogenesis of RNA Virus-Associated Bone Disorders.

Reviews in medical virology
2026

Entomological surveillance in active dengue transmission areas of Santo Domingo de los Tsáchilas - Ecuador: Epidemiological importance of Aedes aegypti and the recent establishment of Aedes albopictus.

Acta tropica
2026

Public responses to risk communication during the 2025 Chikungunya outbreak in China: Implications for future epidemic preparedness.

Preventive medicine
2026

Molecular diagnosis of arboviruses (dengue, Chikungunya, yellow fever, Rift Valley fever, Mayaro, West Nile, and Zika viruses) in non-malaria acute febrile illnesses in Kenya's Garissa County, July 2023, and Mombasa County, July 2024.

BMC infectious diseases
2026

Age- and comorbidity-stratified clinical profiles of hospitalized chikungunya patients, China, 2025.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2026

Arboviruses circulation in Guinea: Overview and perspectives for public health.

PLoS neglected tropical diseases
2025

Seminal Fluid Adipokinetic Hormone Increases Insemination Refractoriness in Female Aedes aegypti.

bioRxiv : the preprint server for biology
2026

Emerging viroporins, RBP dynamics, and skeletal remodeling: Targeting liquid-liquid phase separation for dual antiviral and bone-protective therapies.

Molecular aspects of medicine
2026

MicroRNAs profiling in malaria and arbovirus coinfection: A systematic review protocol.

PloS one
2026

Seroprevalence of chikungunya virus infection in East Delhi over a decade: A retrospective study.

Tropical doctor
2026

Zika Virus Outbreak - Bangladesh, September-December 2024.

MMWR. Morbidity and mortality weekly report
2026

Modeling and control of Chikungunya with chronic infection.

Infectious Disease Modelling
2025

Insecticide resistance dynamics in Aedes mosquitoes in Ghana.

GigaByte (Hong Kong, China)
2025

In Silico Characterization of Conserved Epitopes in Alphavirus E2 Proteins: A Promising Approach for Pan-vaccine Design.

ACS omega
2025

Vimkunya - Hope Against Chikungunya: Science, Safety, and Access.

WMJ : official publication of the State Medical Society of Wisconsin
2025

Age-specific chikungunya outbreak response immunisation strategies in Brazil: a modelling study.

EClinicalMedicine
2025

Spatial and temporal distribution of Culex and Aedes mosquitoes in Ghana.

GigaByte (Hong Kong, China)
2026

Emergence of Chandipura viral encephalitis in India: a strategic approach to combat a fatal viral epidemic.

Annals of medicine and surgery (2012)
Ver todos os 5.204 no EuropePMC

Associações

Organizações que acompanham esta doença — pra ter apoio e orientação

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Comunidades

Grupos ativos de quem convive com esta doença aqui no Raras

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Doenças relacionadas

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. In-utero exposure to chikungunya and child morbimortality: a population-based study using linked routine data.
    Nature communications· 2026· PMID 41865012mais citado
  2. A disease-agnostic approach to ensemble learning for infectious disease forecasting.
    Nature communications· 2026· PMID 41862508mais citado
  3. Characterization of arbovirus infections in patients within Haiti by screening discarded malaria rapid diagnostic test cassettes.
    PLoS neglected tropical diseases· 2026· PMID 41860982mais citado
  4. The SMARCA4-TMEM47 axis plays an essential role in chikungunya virus RNA replication.
    Proceedings of the National Academy of Sciences of the United States of America· 2026· PMID 41849385mais citado
  5. Noise and neglect: Social-media signals expose attention gaps for dengue, chikungunya, lymphatic filariasis and kala-azar in India's vector-borne NTDs.
    PLoS neglected tropical diseases· 2026· PMID 41849302mais citado
  6. Chikungunya vaccine.
    Dis Mon· 2026· PMID 41991419recente
  7. A targeted amplicon sequencing panel for cost-effective high-throughput genotyping of Aedes aegypti.
    Parasit Vectors· 2026· PMID 41987308recente
  8. Dengue Incidence, Seroprevalence, and Expansion Factors from Active Surveillance, Brazil, 2016-2021.
    Emerg Infect Dis· 2026· PMID 41986958recente
  9. Evaluation of Effectiveness of Autocidal Gravid Ovitraps for Preventing Zika Virus Infection, Puerto Rico, USA.
    Emerg Infect Dis· 2026· PMID 41986937recente
  10. Investigating antibody cross-reactivity and transmission dynamics of alphaviruses and flaviviruses using a multiplex serological assay.
    Nat Commun· 2026· PMID 41986360recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:324625(Orphanet)
  2. MONDO:0017941(MONDO)
  3. GARD:6038(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Artigo Wikipedia(Wikipedia)
  6. Q243257(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Chikungunya
Compêndio · Raras BR

Chikungunya

ORPHA:324625 · MONDO:0017941
Prevalência
Unknown
Herança
Not applicable
CID-10
A92.0 · Febre de Chikungunya
CID-11
Ensaios
21 ativos
Início
All ages
Prevalência
0.0 (Worldwide)
MedGen
UMLS
C0008055
EuropePMC
Wikidata
Wikipedia
Papers 10a
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