Distonia oromandibular

Brain Networks in Dystonia

NCT03042962

RECRUTANDO

A Comparative Study of GPI's DBS and Pallidotomy in the Treatment of Meige Syndrome

NCT04618887

DESCONHECIDO

Dystonia Coalition Projects

NCT04156022

DESCONHECIDO

Deep Brain Stimulation in Patients With Dystonia

NCT00773604

CONCLUÍDO

Efficacy of Levetiracetam in Oromandibular and Cranial Dystonia

NCT02199509

CONCLUÍDO

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7 ensaios clínicos encontrados, 1 ativos.

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NCT04618887 · A Comparative Study of GPI's DBS and Pallidotomy in the Trea…UNKNOWN

NCT04156022 · Dystonia Coalition ProjectsEncerrado

NCT00773604 · Deep Brain Stimulation in Patients With DystoniaConcluído

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NCT02199509 · Efficacy of Levetiracetam in Oromandibular and Cranial Dysto…Concluído

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Publicações mais relevantes

Timeline de publicações

230 papers (10 anos)

#1

Association of low-frequency oscillations with target selection between the subthalamic nucleus and globus pallidus internus in blepharospasm-oromandibular dystonia.

Journal of neurology2026 Mar 13

Stimulation of the subthalamic nucleus (STN) and globus pallidus internus (GPi) is an effective target for treating blepharospasm-oromandibular dystonia, but the individual optimal remains unclear. Thirteen patients with blepharospasm-oromandibular dystonia were enrolled. Bilateral STN and GPi electrodes were implanted and externalized, and the signal of the two targets was recorded simultaneously. The power spectrum and burst characteristics were analyzed to see how they were related to symptom severity. The 1 year follow-up revealed an overall improvement rate of 76.21% ± 12.51%. Those with GPi as final targets showed higher band power and longer average burst duration in the 5.5-12 Hz band in the GPi compared to the STN (P < 0.05). Conversely, those with STN as final targets showed higher band power and longer average burst duration in the 6-10 Hz band in the STN compared to the GPi (P < 0.05). Exclusion of shorter low-frequency bursts led to higher correlation coefficients with BFMDRS-M scores in both the STN and GPi groups (P < 0.01). Our study suggests that low-frequency oscillatory features may be associated with therapeutic target selection for DBS in blepharospasm-oromandibular dystonia. These findings may help inform target selection strategies and warrant prospective validation for their value in supporting long-term clinical outcomes.

#2

Analysis of risk factors for Meige syndrome and construction and validation of a clinical prediction nomogram model.

Frontiers in neurology2026

Meige syndrome (MS) is a craniocervical dystonia characterized by blepharospasm and oromandibular dystonia. Its etiology remains unclear, and clinical diagnosis is often delayed. Currently, there is a lack of effective risk prediction tools, making early intervention challenging. To systematically analyze the risk factors for MS and develop and validate a clinical prediction nomogram model based on clinical indicators to facilitate early risk assessment. A retrospective case-control study was conducted, enrolling 450 confirmed MS patients and 450 controls from the Third People's Hospital of Henan Province between January 2021 and December 2023. Univariate and multivariate logistic regression analyses were performed to identify independent risk factors, and a nomogram prediction model was constructed based on regression coefficients. The model's discriminative ability, calibration, and clinical utility were evaluated using receiver operating characteristic curves, calibration curves, and decision curve analysis (DCA). Multivariate analysis revealed that a history of thyroid disease (OR = 12.797), psychiatric disorders (OR = 6.892), and head/face surgery (OR = 3.466) were independent risk factors for MS, while female sex (OR = 1.87) and cerebrovascular disease (OR = 1.999) were moderate-risk factors. Notably, smoking (OR = 0.411), alcohol consumption (OR = 0.396), and diabetes (OR = 0.534) showed protective associations. The constructed nomogram model demonstrated strong predictive performance in both the training and validation sets (AUC = 0.789 and 0.800, respectively). Calibration curves indicated high consistency between predicted and observed probabilities, and DCA confirmed its clinical applicability. We developed and validated a clinical prediction nomogram for MS incorporating eight independent predictors: history of thyroid disorders, psychiatric disorders, head/face surgery, female sex, cerebrovascular disease, as well as protective factors including smoking, alcohol consumption, and diabetes. The model provides a quantifiable tool for early risk stratification and targeted intervention in clinical practice. However, further optimization and validation through multicenter prospective studies are warranted.

#3

Case Report: Effective management of a Meige syndrome patient with subthalamic stimulation-induced dyskinesia through timed stimulation programming of different contacts.

Frontiers in human neuroscience2026

Meige syndrome is a rare adult-onset segmental dystonia characterized by blepharospasms and oromandibular dystonia. Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an established treatment, but it can lead to stimulation-induced dyskinesia (SID) in some patients. Refractory SID in Meige syndrome after STN-DBS is clinically challenging. We report a case of a Meige syndrome patient who developed refractory SID following STN-DBS and was successfully managed using a novel timed-stimulation programming strategy employing different contacts. A 47-year-old female with a two-year history of Meige syndrome developed refractory SID after the treatment of STN-DBS. Various programming strategies were attempted, including monopolar stimulation, interleaved stimulation, bipolar stimulation et al., but none achieved a balance between symptom control and SID. A novel approach involving timed alternation between ventral contacts (contacts 3 and 7) and dorsal contacts (contacts 4 and 8) was implemented. The stimulation was gradually programmed, the duration of ventral stimulation was increased while decreasing dorsal stimulation. Eventually, the patient achieved significant symptom improvement without SID. The reconstruction of the volume of tissue activated (VTA) revealed that this stimulation strategy likely modulates the neural circuits of pallidothalamic fibers (PTF) to suppress SID. This case demonstrates that this noval timed stimulation programming can effectively manage refractory SID in Meige syndrome patients, offering a viable alternative when conventional methods fail. The findings suggest that PTF stimulation plays a key role in SID suppression, and this strategy warrants further investigation in larger cohorts.

#4

Targeted Myofascial Release in Oromandibular Dystonia: A Case Report on Non-Invasive Tremor Reduction and Functional Recovery.

NeuroRehabilitation2026 Mar

IntroductionOromandibular dystonia (OMD) is a rare, disabling movement disorder causing involuntary jaw and neck tremors. Traditional treatments, such as botulinum toxin (BTX) injections, can have side effects or limited efficacy. This case report aims to explore the effects of a non-invasive, multimodal intervention, including targeted myofascial release (MFR), on tremor severity, balance, gait, and functional independence in a patient with OMD.Case PresentationThe patient, a 65-year-old female, presented with severe jaw tremors, impaired balance, and functional limitations in daily activities. Her symptoms were assessed pre-intervention using standardized tools, including the Berg Balance Scale (BBS), Tinetti Assessment Tool (TAT), Tremor Rating Grid (TRG), Gait Assessment Instrument (GAIT), Bristol Activities of Daily Living Scale (BADLS), Barthel Index (BI), and Katz Index (KI).InterventionThe patient underwent 12 sessions over 4 weeks of targeted MFR, combined with core stabilization, jaw exercises, and sensory stimulation. Treatment progressed in three phases: tone control and trunk preparation, direct neck and jaw MFR, and functional stabilization with jaw resistance and speech exercises.OutcomesThe intervention led to substantial improvements in tremor severity (TRG: 16→5), balance (BBS: 4→27), gait (GAIT: 6→23), and functional independence (BADLS: 21→11; Barthel: 30→70; Katz: 3→6).ConclusionThis case demonstrates that targeted MFR is a safe, non-invasive intervention that can substantially improve tremor, balance, gait, and functional independence in OMD. These findings highlight the novelty and clinical relevance of the approach and support the need for larger controlled studies.

#5

DYT-AOPEP: A case series from India expanding the clinical and genetic spectrum.

Parkinsonism & related disorders2026 Feb 10

DYT-AOPEP (Aminopeptidase O) or DYT31 is a rare, newly discovered genetic cause of autosomal recessive monogenic adult-onset isolated dystonia. We describe three Indian patients with likely pathogenic variants in the AOPEP gene, expanding the clinicogenetic spectrum DYT-AOPEP. First proband presented with adult-onset generalised isolated dystonia, which was medically refractory, but responded to GPi-DBS. He harboured a homozygous splice site variant (NM_001193329.3:c.1916+1G > C). The second proband had adult-onset isolated generalised dystonia without any family history, which started in her lower limb. She carried a homozygous stop-gain variant [NM_001193329.3:c.617dup; (p.Tyr206∗)]. The third proband had oromandibular dystonia progressing to generalised dystonia with a homozygous missense stop-gain variant [NM_001193329.3:c.895C > T; (p.Arg299∗)]in the AOPEP gene. A total of eighteen patients have been described in the literature so far with variable age of onset, isolated limb-onset dystonia, or cervical dystonia, most characteristically retrocollis and is sometimes associated with parkinsonism. Some patients develop mixed hyperkinetic movement disorders. Pallidal deep-brain stimulation is a good therapeutic option in medically refractory cases. AOPEP is a recently identified gene within the expanding spectrum of dystonia-associated genes. An increasing number of patients with pathogenic variants have been reported in recent studies, supporting its consideration for inclusion in dystonia gene panels and broader population-based screening. Benign essential blepharospasm (BEB) is a persistent focal cranial dystonia characterized by involuntary, repeated, and frequently debilitating spasms of the orbicularis oculi muscles. Blepharospasm is a disease characterized by an increased rate of bilateral eyelid closure, mainly due to involuntary contraction of the orbicularis oculi muscles (see Image. Typical Blepharospasm). The disorder typically begins with excessive blinking, ocular discomfort, or sporadic eyelid fluttering, and may progress to persistent, powerful spasms that obstruct vision. Once regarded as a purely motor disorder, recent research indicates that BEB represents a multifaceted malfunction within central sensorimotor networks, encompassing the basal ganglia, cerebellum, thalamus, and cortical inhibitory pathways. These anomalies diminish the capacity to inhibit reflexive blinking and enhance motor reactions to sensory stimuli. Over time, the natural history typically demonstrates progressive symptom exacerbation, with several people eventually experiencing functional blindness—characterized by an inability to maintain sufficient eyelid elevation for visual tasks. Contemporary cohort studies validate the progressive and debilitating characteristics of BEB, evidencing significant declines in quality of life and social engagement. Extensive epidemiological data underscore BEB as a chronic neurological condition with considerable individual and social impact. Blepharospasm is a type of dystonia, a movement disorder characterized by sustained or intermittent muscle contractions that lead to abnormal, repetitive movements or postures, often patterned and sometimes twisting or tremulous. In most dystonias, voluntary action typically leads to exacerbation of dystonia due to overactivation of muscles. Dystonia can potentially affect any part of the body and can present at a wide range of ages. This disorder can be classified according to its distribution across the body: Focal dystonia refers to dystonia that affects only 1 isolated region of the body. Segmental dystonia refers to dystonia that affects 2 or more contiguous regions of the body. Multifocal dystonia refers to dystonia affecting 2 or more noncontiguous regions. Hemidystonia refers to a form of dystonia that affects half of the body. Generalized dystonia refers to dystonia affecting the trunk and 3 other sites. Dystonia can have a static or progressive course. Furthermore, the variability of symptoms can be classified according to how often they occur: Persistent dystonia refers to dystonia that remains at the same level throughout the day. Action-specific dystonia refers to dystonia that occurs only when performing a specific activity. Diurnal fluctuation refers to dystonia that varies throughout the day, with circadian variation in severity. Paroxysmal dystonia refers to sudden episodes of dystonia typically induced by a trigger. Examples of focal dystonia include blepharospasm, oromandibular dystonia, writer's cramp, spasmodic dysphonia, and torticollis. Blepharospasm is a focal dystonia characterized by simultaneous contraction of agonist and antagonist muscles, resulting in involuntary eyelid closure; the first report of patients with blepharospasm was a description of 10 patients by Henri Meige in 1910. The patients reported in this study had involuntary eyelid closure associated with jaw muscle contraction. In his paper, Meige named this phenomenon Convulsions de la Face ("convulsions of the face"). BEB originates from the dysregulated function of the orbicularis oculi muscle, which is innervated by the facial nerve and modulated by brainstem and basal ganglia circuits. Pathological excitability in these circuits leads to heightened blinking responses to trivial stimuli, such as bright light, dryness, or emotional stress. Neurophysiological investigations indicate increased blink reflex sensitivity and diminished inhibitory control, suggesting that BEB disrupts normal sensorimotor gating. Furthermore, ocular surface disorders significantly contribute to symptom exacerbation. Dry eye disease is prevalent in BEB, and elevated blink frequency appears to be both a catalyst and a result of tear-film instability. Research indicates that tear hyperosmolarity, elevated levels of inflammatory cytokines, and mechanical irritation of the ocular surface may exacerbate dystonic contractions, thereby creating a positive feedback loop between sensory irritation and motor dysfunction. Alterations in the ocular surface constitute an additional aspect of the normal progression of BEB. Excessive blinking intensity and frequency lead to tear-film instability, lid wiper epitheliopathy, meibomian gland strain, and epithelial microtrauma. Research investigating the ocular surface pre- and post-botulinum toxin injections demonstrates persistent anomalies, such as diminished tear breakup time, heightened corneal staining, and mechanical damage in the lid wiper area, which frequently ameliorate following the regulation of spasms. Long-term observational data indicate that BEB is linked to significant psychological effects, including anxiety, depression, and sleep disturbances, all of which correlate with heightened dystonic severity. These non-motor manifestations further underscore the multimodal nature of BEB and its significant impact on patient well-being.

Publicações recentes

Reviving Hope: Overcoming Deep Brain Stimulation Failure With Partial Cranial Nerve Radiofrequency Ablation in Primary Meige Syndrome.

Brain Behav2026 Apr

Shared and Specific Patterns of Brain Functional Network Abnormalities in Patients With Idiopathic Dystonia and Across Subtypes.

CNS Neurosci Ther2026 Apr

A plastic surgery approach to Meige syndrome: Botulinum toxin for rebalancing facial dystonia and aesthetics - A case report.

JPRAS Open2026 May

Chorea-acanthocytosis masquerading as a progressive seizure disorder with apparent early immunotherapy responsiveness.

BMJ Neurol Open2026

Association of low-frequency oscillations with target selection between the subthalamic nucleus and globus pallidus internus in blepharospasm-oromandibular dystonia.

J Neurol2026 Mar 13

Ver todas no PubMed

📚 EuropePMC188 artigos no totalmostrando 198

Association of low-frequency oscillations with target selection between the subthalamic nucleus and globus pallidus internus in blepharospasm-oromandibular dystonia.

Targeted Myofascial Release in Oromandibular Dystonia: A Case Report on Non-Invasive Tremor Reduction and Functional Recovery.

NeuroRehabilitation

Analysis of risk factors for Meige syndrome and construction and validation of a clinical prediction nomogram model.

DYT-AOPEP: A case series from India expanding the clinical and genetic spectrum.

Real-World Retrospective Safety Analysis of OnabotulinumtoxinA for the Treatment of Patients with Chronic Migraine and Concomitant Therapeutic Indications.

Pain and therapy

Case reports in neurological medicine

Botulinum Toxin A in Poststroke Oromandibular Dystonia: Case Reports.

Frontiers in human neuroscience

Case Report: Effective management of a Meige syndrome patient with subthalamic stimulation-induced dyskinesia through timed stimulation programming of different contacts.

Globus pallidus internus versus subthalamic nucleus deep brain stimulation for Meige syndrome: a retrospective study on short- and long-term efficacy.

Journal of neurosurgery

Treatment of Blepharospasm with Methylphenidate: A Telemedicine Study.

Oromandibular Dystonia as the First Reported Presentation of SCA43 Due to MME c.94_95dup (p.Val33Argfs*10).

Neurology

Journal of the American Dental Association (1939)

Multiple system atrophy presenting as oromandibular dystonia and bruxism.

Peripherally Induced Oromandibular Dystonia Following Orthognathic Surgery.

The Effective Way of Botulinum Toxin Injection to Reduce Bite Force: Preliminary Study.

Real-world pharmacovigilance of risperidone: Analysis based on FAERS reports from physicians and pharmacists.

PloS one

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery

[Meige syndrome with dyspnea as main manifestation: a report of one case and literature review].

Lost in Cognition: Paraneoplastic Rhombencephalitis With Anti-Ri/Antineuronal Nuclear Antibody Type 2 (ANNA-2) Antibodies Presenting as Rapid-Onset Cognitive Decline and Ophthalmoplegia-Ataxia With Reversible Brainstem Lesion.

Annals of Indian Academy of Neurology

Environmental Risk Factors in Isolated Dystonia: A Systematic Scoping Review.

Surgical neurology international

Deep brain stimulation for Meige syndrome.

Chewing Dystonia and Sensory Modulation: An Exploratory Study of Intraoral Lidocaine Effects.

Rare PANK2 variants and pantothenate-kinase-associated neurodegeneration in the Dominican Republic.

Brain communications

Tremor and other hyperkinetic movements (New York, N.Y.)

Oromandibular Dystonia and Dysphagia in Hyperglycemic Brainstem Dysfunction.

Toxicon : official journal of the International Society on Toxinology

Botulinum toxin treatment of lingual dystonia, oromandibular dystonia and bruxism-A review and update.

Comparative study of brain activity and functional connectivity in blepharospasm and blepharospasm-oromandibular dystonia.

Clinico-genetic profile of case series of six Tamilian chorea-acanthocytosis families with VPS13A mutations from South India.

The Journal of craniofacial surgery

Unraveling a Decade of Misdiagnosis and Suffering: A Pioneering Diagnostic and Therapeutic Breakthrough in Resolving Chronic Oromandibular Dystonia After Years of Failed Multidisciplinary Approaches.

Asian journal of psychiatry

Accelerated continuous theta burst stimulation of supplementary motor area in management of oromandibular dystonia: A case study.

The Journal of international medical research

Isolated neurological symptoms of Wilson's disease manifesting as focal epileptic seizures without hepatic involvement: Insights from a case report.

Anti-Ri Associated Paraneoplastic Cervical Dystonia and Laryngospasm in a Patient with Nasopharyngeal Carcinoma.

Noro psikiyatri arsivi

Patient Burden in Dystonia Diagnosis and Botulinum Toxin Treatment: A Nationwide Survey in Turkey.

Brain and behavior

Epilepsy & behavior reports

Myoclonic status epilepticus with dystonia-like symptoms in patients with dementia: Report of two cases.

Association between functional alterations and specific transcriptional expression patterns in craniocervical dystonia.

The World's Oldest Description of Oromandibular Dystonia.

Treatment with OnabotulinumtoxinA for Oromandibular Dystonia: A Systematic Review and Meta-Analysis.

Journal of neural transmission (Vienna, Austria : 1996)

Optimal botulinum toxin therapy of dystonia in Germany: what would it cost?

Journal of neural transmission (Vienna, Austria : 1996)

Spasmodic dysphonia: the need for a combined neurological and phoniatric approach.

Tremor and other hyperkinetic movements (New York, N.Y.)

Risk of Spreading in Adult-onset Dystonia.

The British journal of oral & maxillofacial surgery

Efficacy of the Hegab temporomandibular joint splint in treating patients diagnosed with dystonia with or without systemic involvement: A report of 14 cases.

Acupuncture for Meige syndrome: A case report.

Explore (New York, N.Y.)

Dental and medical problems

Movement disorders of the stomatognathic system: A blind spot between dentistry and medicine.

Oral and maxillofacial surgery

Peripherally induced movement disorders in the stomatognathic system after oral surgical or dental procedures.

Iranian journal of child neurology

Levofloxacin-Induced Oromandibular Dystonia in a 9-Year-Old Patient.

A Presentation of Meige Syndrome With Associated Upper Motor Neuron Symptoms.

Clinical medicine insights. Case reports

Surgical Myectomy and Myotomy for Refractory Blepharospasm in Meige Syndrome Patients: A Case Report.

Surgical neurology international

Concurrent glossopharyngeal neuralgia and oromandibular dystonia resolved after microvascular decompression of the trigeminal and glossopharyngeal nerve: A rare presentation.

Arquivos de neuro-psiquiatria

Effects of onabotulinum toxin type A injections in patients with Meige's syndrome.

Progressive thalamic nuclear atrophy in blepharospasm and blepharospasm-oromandibular dystonia.

Brain communications

International journal of molecular sciences

Genetic Update and Treatment for Dystonia.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Oromandibular dystonia: from onset to spread a multicenter italian study.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

A Novel Homozygous Variant in the MCOLN1 Gene Associated With Severe Oromandibular Dystonia and Parkinsonism.

Journal of the Korean Association of Oral and Maxillofacial Surgeons

Ultrasound-guided intraoral botulinum toxin injection into the lateral pterygoid muscle for chronic temporomandibular joint dislocation.

Oromandibular Dystonia After Low-Dose Olanzapine Treatment in a Patient With Marchiafava-Bignami Disease With Demyelinating Lesions in the Corpus Callosum: A Case Report.

Intermediate Syndrome Presenting as Extrapyramidal Oromandibular Dystonia Due to Organophosphorus Inhalation: A Rare Case Report.

Tremor and other hyperkinetic movements (New York, N.Y.)

New-Onset Focal Task Specific Oromandibular Dystonia in Association with Quran Recitation: A Case Series.

Task-Specific Lingual Dystonia During Japanese Religious Services.

Dystonia (Lausanne, Switzerland)

Case report: Lingual dystonia symptoms treated with botulinum toxin in patients with THAP1 mutation.

Levodopa-Induced Jaw and Facial Dystonia in a Case of Progressive Supranuclear Palsy with Blepharospasm.

Oromandibular Dystonia as a Side Effect of Methotrexate.

Task-specific oromandibular dystonia secondary to chewing Khat (Catha edulis)- A series of 35 cases.

Journal of pediatric rehabilitation medicine

Treatment of oromandibular dystonia with botulinum toxin A improves apnea in a teenager with quadriplegic cerebral palsy: A case report.

Phenotypic Variability in Acquired and Idiopathic Dystonia.

[Efficacy of CT-guided partial radiofrequency ablation of bilateral responsible cranial nerves in the treatment of Meige syndrome].

Zhonghua yi xue za zhi

Multiple system atrophy associated with Meige syndrome: A rare case report.

Radiology case reports

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

Abnormalities in the face primary motor cortex in oromandibular dystonia.

Emergency medicine international

Clinical Presentation and Management of Acute Dystonia from Drug Abuse or Misuse in Adolescents and Young Adults: A Retrospective Cohort Study in Bangkok, Thailand.

Robot-assisted bilateral deep brain electrode implantation to treat isolated oromandibular dystonia.

Asian journal of surgery

Tremor and other hyperkinetic movements (New York, N.Y.)

Oromandibular Dystonia: Clinical and Demographic Data from Eight-Two Patients.

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology

[The efficacy and safety of nerve loop blocking in the treatment of blepharospasm in Meige syndrome].

A KMT2B Frameshift Variant Causing Focal Dystonia Restricted to the Oromandibular Region After Long-Term Follow-up.

Neurophysiological Basis of Deep Brain Stimulation and Botulinum Neurotoxin Injection for Treating Oromandibular Dystonia.

Internal medicine (Tokyo, Japan)

Lower Cranial Dystonia with Inflated Cheeks: A Case of Dystonic Respiratory Failure.

Tardive Oromandibular Dystonia Induced by Trazodone: A Clinical Case and Management from the Perspective of the Dental Specialist.

Botulinum Toxin, a Drug with Potential Interest for Dentists-An Introduction.

Effects of Botulinum Toxin Therapy on Health-Related Quality of Life Evaluated by the Oromandibular Dystonia Rating Scale.

Frontiers in neuroscience

CT-guided radiofrequency ablation of the extracranial cranial nerve for the treatment of Meige's syndrome.

Dystonia (Lausanne, Switzerland)

Clinical Features and Evolution of Blepharospasm: A Multicenter International Cohort and Systematic Literature Review.

The Prevalence of Idiopathic or Inherited Isolated Dystonia: A Systematic Review and Meta-Analysis.

Mental health and quality of life in patients with craniofacial movement disorders: A cross-sectional study.

Clinical parkinsonism & related disorders

Patient selection and injection techniques for botulinum neurotoxin in oromandibular dystonia.

The epidemiology of dystonia: the Hannover epidemiology study.

Movement disorders of the mouth: a review of the common phenomenologies.

Outcome of pallidal deep brain stimulation for treating isolated orofacial dystonia.

Acta neurochirurgica

Pallidus Stimulation for Chorea-Acanthocytosis: A Systematic Review and Meta-Analysis of Individual Data.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Botulinum toxin injections in jaw-opening dystonia. The lateral pterygoid - maxillary artery problem.

Neuro-ophthalmology (Aeolus Press)

Atypical Blepharospasm with Oromandibular Dystonia Associated with Cerebral Amyloid Angiopathy.

Drug-Induced Oromandibular Dystonia Presenting as Chronic Temporomandibular Joint Dislocation: A Rare Case Report.

Botulinum Toxin Therapy for Oromandibular Dystonia and Other Movement Disorders in the Stomatognathic System.

Annals of Indian Academy of Neurology

Oromandibular Dystonia - A Systematic Review.

Ultrasound-Guided OnabotulinumtoxinA Injections to Treat Oromandibular Dystonia in Cerebral Palsy.

Time to onset and duration of botulinum toxin efficacy in movement disorders.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Genetic screening in patients of Meige syndrome and blepharospasm.

Journal of medical case reports

Changes in pallidal neural activity following long-term symptom improvement from botulinum toxin treatment in DYT6 dystonia: a case report.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

Pathophysiological mechanisms of oromandibular dystonia.

Journal of the American Dental Association (1939)

Oromandibular dystonia and temporomandibular disorders.

Chemodenervation for Oromandibular Dystonia Utilizing Botulinum Toxins.

Clinical neurology and neurosurgery

Anti-N-methyl-D-aspartate receptor encephalitis: An observational and comparative study in Mexican children and adults.

Surgical neurology international

Oro-mandibular dystonia in pediatric moyamoya disease: Two cases report.

Oromandibular Dystonia: A Clinical Examination of 2,020 Cases.

Effects of Botulinum Toxin Type A on Pain among Trigeminal Neuralgia, Myofascial Temporomandibular Disorders, and Oromandibular Dystonia.

Psychiatry and clinical psychopharmacology

Oromandibular Dystonia Treatment With Aripiprazole in an Adolescent Patient 2-Year Follow-Up: A Case Report.

Clinical neurology and neurosurgery

Dose conversion ratio, comparative efficacy, and adverse events after switching from onabotulinum toxin A to abobotulinum toxin A for neurological conditions.

Cranio : the journal of craniomandibular practice

Surface electromyography for evaluating patients with oromandibular dystonia.

Annals of Indian Academy of Neurology

Sleep and other Non-motor Symptoms in Patients with Idiopathic Oromandibular Dystonia and Meige Syndrome: A Questionnaire-based Study.

The Spectrum of Movement Disorders in Neuroacanthocytosis Syndromes: A Video Series.

Sertraline Induced Oromandibular Dystonia and Galactorrhea: A Case Report.

Psychiatria Danubina

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

A Novel COVID Era-Related Oromandibular Dyskinesia: Surgical Mask-Induced Dyskinesia?

Neurological research and practice

Sensory trick effect in craniofacial dystonia as one of the possible impacts of wearing face masks during the COVID-19 pandemic.

Medicina oral, patologia oral y cirugia bucal

Oral health and oral health-related quality of life in patients with oral dystonia indicates their need for dental special care.

Contemporary clinical dentistry

Chorea-acanthocytosis: A Case Report with Review of Oral Manifestations.

Clinical oral investigations

Prevalence and incidence of oromandibular dystonia: an oral and maxillofacial surgery service-based study.

Blepharospasm, Oromandibular Dystonia, and Meige Syndrome: Clinical and Genetic Update.

Journal of translational internal medicine

Experiences on The Administration of Botulinum Toxin in Movement Disorders.

Journal of oral rehabilitation

Temporomandibular disorder-related characteristics and treatment outcomes in Oromandibular Dystonia patients in two different clinical settings: A cross-sectional study.

Case Report: Neuronal Intranuclear Inclusion Disease With Oromandibular Dystonia Onset.

Munchausen syndrome: report of a case and implications for dentists.

General dentistry

American journal of speech-language pathology

Exploring the Psychosocial Impact of Botulinum Toxin Type A Injections for Individuals With Oromandibular Dystonia: A Qualitative Study of Patients' Experiences.

Fortschritte der Neurologie-Psychiatrie

[Therapeutic strategies for oromandibular dystonia].

Expanding the clinical spectrum of adult-onset neuronal intranuclear inclusion disease.

Acta neurologica Belgica

Case Report: Isolated Lingual Dystonia.

F1000Research

Journal of voice : official journal of the Voice Foundation

Progressive Decline in Voice and Voice-Related Quality of Life in X-Linked Dystonia Parkinsonism.

Neuro-degenerative diseases

The Expanding Phenotypic Spectrums Associated with ATP1A3 Mutation in a Family with Rapid-Onset Dystonia Parkinsonism.

Neuromodulation for Restoration of Urinary and Bowel Control.

Microsurgery and Neuromodulation for Facial Spasms.

Refractory dry eye disease associated with Meige's syndrome induced by long-term use of an atypical antipsychotic.

BMC ophthalmology

Development and Validation of a Disease-Specific Oromandibular Dystonia Rating Scale (OMDRS).

A Case of Meige Syndrome Treated With Baclofen.

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova

[Dementia with Lewy bodies in a patient with oromandibular dystonia].

American journal of physical medicine & rehabilitation

Jaw Pain and Oromandibular Dysfunction After a Complex Hospital Course: A Clinical Vignette.

Cervical dystonia: factors deteriorating patient satisfaction of long-term treatment with botulinum toxin.

Neurological research

Movement disorders in children with congenital Zika virus syndrome.

Brain & development

[ADCY5-associated dyskinesia in young children: a case report of a family and an updated review].

Revista de neurologia

Orofacial dystonia and asssociated bulbar symptoms in multiple system atrophy: A blinded video analysis.

Oral appliances in the treatment of oromandibular dystonia: a systematic review.

Acta neurologica Belgica

Oral surgery, oral medicine, oral pathology and oral radiology

Prevalence and clinical characteristics of patients with oromandibular dystonia seen in the orofacial pain clinic: a retrospective study.

Treatment of Blepharospasm and Oromandibular Dystonia with Botulinum Toxins.

Medical and Surgical Treatments for Dystonia.

Neurologic clinics

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Obstructive sleep apnea due to oromandibular dystonia and treated with botulinum toxin.

The British journal of oral & maxillofacial surgery

Oromandibular dystonia: a diagnosis not to miss.

Journal of oral rehabilitation

Distribution of temporomandibular disorders among sleep bruxers and non-bruxers-A polysomnographic study.

CNS neuroscience & therapeutics

Natural history and genotype-phenotype correlation of pantothenate kinase-associated neurodegeneration.

COL6A3 mutation associated early-onset isolated dystonia (DYT)-27: Report of a new case and review of published literature.

Brain & development

Sensory Tricks in Pantothenate Kinase-Associated Neurodegeneration: Video-Analysis of 43 Patients.

Neuropsychopharmacology reports

Therapy-refractory schizophrenia in a patient who previously suffered from Meige's syndrome.

Refractory Open Jaw Oromandibular Tardive Dystonia with a Sensory Trick, Treated with Botulinum Toxin: A Case Report.

American journal of speech-language pathology

The Consequences of Oromandibular Dystonia on Communicative Participation: A Qualitative Study of the Insider's Experiences.

Deep brain stimulation for Meige syndrome: a meta-analysis with individual patient data.

Case reports in psychiatry

Criminal Behaviour Associated with a Novel Mutation in the VPS13A-Gene Causing Chorea-Acanthocytosis.

Prominent Oromandibular Dystonia as Levodopa-induced Dyskinesia in Idiopathic Parkinson's Disease.

Tongue base retraction and airway obstruction in drug-induced oromandibular dystonia.

Neurology

Journal of neurosciences in rural practice

Isolated Lingual Dystonia as the Manifestation of Acute Extrapyramidal Syndrome Induced by Metoclopramide.

Journal of dentistry for children (Chicago, Ill.)

Oromandibular Dystonia Causing Recurrent Mandibular Open Lock in Two Adolescents Managed with Botulinum Toxin.

Task-Specific Oromandibular Dystonia in a Telemarketer.

Journal of medical case reports

Chorea-ballism as a dominant clinical manifestation in heteroplasmic mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome with A3251G mutation in mitochondrial genome: a case report.

Tremor and other hyperkinetic movements (New York, N.Y.)

Familial Spinocerebellar Ataxia Type 2 Parkinsonism Presenting as Intractable Oromandibular Dystonia.

Mandibular Bone Loss after Masticatory Muscles Intervention with Botulinum Toxin: An Approach from Basic Research to Clinical Findings.

Journal of oral rehabilitation

Oromandibular dystonia, mental distress and oro-facial dysfunction-A follow-up 8-10 years after start of treatment with botulinum toxin.

Botulinum Neurotoxin Therapy for Lingual Dystonia Using an Individualized Injection Method Based on Clinical Features.

Facial grimacing and clinical correlates in spinocerebellar ataxia type 3.

Journal of neural transmission (Vienna, Austria : 1996)

Botulinum neurotoxin a therapy efficacy and safety for oromandibular dystonia: a meta-analysis.

Journal of child and adolescent psychopharmacology

Oromandibular Dystonia Related to Sertraline Treatment in a Child.

Setting the record straight: The nosology of tardive syndromes.

Interdisciplinary recognizing and managing of drug-induced tardive oromandibular dystonia: two case reports.

Clinical case reports

Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry

Dental appliance therapy in pantothenate kinase-associated neurodegeneration: Case report.

Oral surgery, oral medicine, oral pathology and oral radiology

The American Academy of Oral Medicine Clinical Practice Statement: Oromandibular dystonia.

Oromandibular Dystonia: Demographics and Clinical Data from 240 Patients.

Multilingual website and cyberconsultations for oromandibular dystonia.

Neurology international

The International journal of prosthodontics

Oromandibular Dystonia-Related Temporomandibular Joint Osteoarthritis: A Case History Report.

Clinical oral investigations

Oromandibular dystonia screening questionnaire for differential diagnosis.

Journal of oral & facial pain and headache

Computer-Aided Design/Computer-Assisted Manufacture-Derived Needle Guide for Injection of Botulinum Toxin into the Lateral Pterygoid Muscle in Patients with Oromandibular Dystonia.

Botulinum Neurotoxin Injection for the Treatment of Recurrent Temporomandibular Joint Dislocation with and without Neurogenic Muscular Hyperactivity.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Pilot Single-Blind Trial of AbobotulinumtoxinA in Oromandibular Dystonia.

Botulinum toxin in movement disorders.

Toxicon : official journal of the International Society on Toxinology

Systematic review of botulinum toxin treatment for oromandibular dystonia.

The nosology of tardive syndromes.

The Journal of prosthetic dentistry

Multidisciplinary management of a partially edentulous patient with oromandibular dystonia: A clinical report.

Clinical and Phenomenological Characteristics of Patients with Task-Specific Lingual Dystonia: Possible Association with Occupation.

Journal of oncology practice

Capecitabine-Related Neurotoxicity Presenting as Oromandibular Dystonia.

Long-term clinical outcome of bilateral pallidal stimulation for intractable craniocervical dystonia (Meige syndrome). Report of 6 patients.

Journal of prosthodontic research

Sensory trick splint as a multimodal therapy for oromandibular dystonia.

Tremor and other hyperkinetic movements (New York, N.Y.)

Speech-Language Pathology Evaluation and Management of Hyperkinetic Disorders Affecting Speech and Swallowing Function.

Persistent oromandibular dystonia and angioedema secondary to haloperidol.

BMJ case reports

Toxicon : official journal of the International Society on Toxinology

An update on new and unique uses of botulinum toxin in movement disorders.

Exploratory structural assessment in craniocervical dystonia: Global and differential analyses.

PloS one

Case reports in dentistry

Management of Oromandibular Dystonia: A Case Report and Literature Update.

American journal of speech-language pathology

Self-Rated Communication-Related Quality of Life of Individuals With Oromandibular Dystonia Receiving Botulinum Toxin Injections.

Journal of dentistry (Shiraz, Iran)

Etiology, Diagnosis and Management of Oromandibular Dystonia: an Update for Stomatologists.

Seminars in speech and language

Perspectives on the Psychosocial Management of Oromandibular Dystonia.

Botulinum Toxin Therapy for Parkinson's Disease.

Seminars in neurology

Bilateral pallidotomy for Meige syndrome.

Acta neurochirurgica

Cefixime-induced Oromandibular Dystonia in an Adult: A Case Report.

Current drug safety

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

The therapeutic usage of botulinum toxin (Botox) in non-cosmetic head and neck conditions - An evidence based review.

How Many Dystonias? Clinical Evidence.

Meige's syndrome: History, epidemiology, clinical features, pathogenesis and treatment.

How Do I Inject Botulinum Toxin Into the Lateral and Medial Pterygoid Muscles?

Case Report of a Severe Recurrent Tongue Self-Injury in an Infant With Dystonia.

Pediatrics

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery

Surgical intervention for oromandibular dystonia-related limited mouth opening: Long-term follow-up.

Journal of speech, language, and hearing research : JSLHR

Clinical Characteristics of Voice, Speech, and Swallowing Disorders in Oromandibular Dystonia.

Oromandibular Dystonia: A Case Report of the Lateral Pterygoid Muscle Involvement and Treatment with Botulinum Toxin A.

Clinics and practice