Paralisia do nervo que move o olho.
Introdução
O que você precisa saber de cara
Paralisia do nervo que move o olho.
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Entender a doença
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Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Partes do corpo afetadas
+ 121 sintomas em outras categorias
Características mais comuns
Os sintomas variam de pessoa para pessoa. Abaixo estão as 247 características clínicas mais associadas, ordenadas por frequência.
Linha do tempo da pesquisa
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Genética e causas
O que está alterado no DNA e como passa nas famílias
Genes associados
6 genes identificados com associação a esta condição.
Acts as a transcriptional activator or repressor (PubMed:27181683). Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, osteoclast, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G
Nucleus
Multicentric carpotarsal osteolysis syndrome
A rare skeletal disorder, usually presenting in early childhood with a clinical picture mimicking juvenile rheumatoid arthritis. Progressive destruction of the carpal and tarsal bone usually occurs and other bones may also be involved. Chronic renal failure is a frequent component of the syndrome. Intellectual disability and minor facial anomalies have been noted in some patients.
Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells
CytoplasmNucleus
Duane-radial ray syndrome
Disorder characterized by the association of forearm malformations with Duane retraction syndrome.
Catalytic subunit of the DNA polymerase zeta complex, an error-prone polymerase specialized in translesion DNA synthesis (TLS). Lacks an intrinsic 3'-5' exonuclease activity and thus has no proofreading function
Nucleus
Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature (By similarity). Mediates anti-angiogenic signaling in respons
Cell membraneCell projection, lamellipodium membrane
Congenital heart defects, multiple types, 9
An autosomal recessive disorder characterized by congenital developmental abnormalities involving structures of the heart. CHTD9 features include common arterial trunk, tetralogy of Fallot, interrupted aortic arch, right aortic arch, ventricular hypoplasia, and hypoplastic left heart, as well as other vascular and valvular anomalies.
GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance
Duane retraction syndrome 2
A form of Duane retraction syndrome, a congenital eye movement disorder characterized by a failure of cranial nerve VI (the abducens nerve) to develop normally, resulting in restriction or absence of abduction, adduction or both, narrowing of the palpebral fissure, and retraction of the globe on attempted adduction. Undiagnosed in children, it can lead to amblyopia, a permanent uncorrectable loss of vision.
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity (PubMed:21985311). The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both (PubMed:21985311, PubMed:32961270). Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isofo
Cytoplasm, cytosolCell membraneCytoplasm, cytoskeletonCell projection, axonCell projection, dendriteSecreted
Variantes genéticas (ClinVar)
528 variantes patogênicas registradas no ClinVar.
Vias biológicas (Reactome)
15 vias biológicas associadas aos genes desta condição.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Paralisia oculomotora
Selecione um estado ou use sua localização para ver resultados.
Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.
Pesquisa ativa
Ensaios clínicos abertos e novidades científicas recentes
Pesquisa e ensaios clínicos
Nenhum ensaio clínico registrado para esta condição.
Publicações mais relevantes
Pediatric Cranial Nerve Palsies.
Cranial nerve palsies in children offer unique challenges distinct from those in adults, and typically arise from congenital, traumatic, neoplastic, or postinfectious inflammatory disease. With rare reports of diplopia, diagnosis depends on indirect signs such as abnormal head posture, strabismus, or abnormal gaze. The oculomotor (III), trochlear (IV), and abducens (VI) nerves follow sometimes long, intricate courses from the brainstem to the target muscle(s) within the orbit. Accurate diagnosis requires integrating anatomic understanding with subtle clinical presentations and imaging findings, and management must emphasize limitations of congenital disease while relying on neural plasticity and adaptive behaviors. Advances in neuroimaging, molecular genetics, and surgical techniques have greatly improved time to diagnosis and treatment outcomes.
Update on Congenital Cranial Dysinnervation Disorders (CCDDs).
Congenital cranial dysinnervation disorders (CCDDs) are a group of rare, nonprogressive conditions characterized by abnormal development of the cranial motor nerves and variable ocular motility deficits, ptosis, incomitant strabismus, and facial palsy. Advances in genetics and neuroimaging have revealed that these disorders result from defects in neuronal differentiation or axon guidance of the cranial motor neurons. Duane retraction syndrome, the most common CCDD, results from the absence of the abducens nerve and innervation of the lateral rectus by oculomotor nerve axons; causative genes include CHN1, MAFB, HOXA1, SALL4, and EBF3, although most cases do not have a genetic diagnosis. Congenital fibrosis of the extraocular muscles (CFEOM), results from variants in KIF21A, PHOX2A, TUBB3, or other tubulin genes, and affects the oculomotor and trochlear nerves. Horizontal gaze palsy with progressive scoliosis (HGPPS), caused by ROBO3 loss of function, arises from failure of axonal midline crossing in the brainstem. Moebius syndrome, defined by abducens and facial nerve palsies, has no identified genetic cause and may result from non-Mendelian causes. Additional CCDDs with atypical or syndromic presentations are linked to COL25A1, ECEL1, and ACKR3, although many do not have a genetic explanation. The expanding list of CCDD-associated genes highlights shared developmental pathways, including neuronal differentiation, axon guidance, and microtubule dynamics. Improved genetic diagnosis informs prognosis and multidisciplinary management. This review synthesizes current understanding of CCDDs, emphasizing the shift from phenotypic classification to molecular subtyping, and underscores the importance of ongoing research to resolve genetically unsolved cases and refine diagnostic and therapeutic strategies.
Selective Nasal Anterior Superior Oblique Tenectomy for the Treatment of Superior Oblique Myokymia.
Superior oblique myokymia is a rare condition characterized by spontaneous episodes of high frequency, low amplitude, usually unilateral torsional oscillopsia. Surgical treatment is indicated when medical therapy fails to improve symptoms. The traditional surgical recommendation is an ipsilateral full-tendon superior oblique tenectomy to remove all attachments of the superior oblique tendon to the sclera. This approach will likely result in a secondary superior oblique palsy, requiring simultaneous weakening of the ipsilateral inferior oblique muscle. We report a patient presenting with diplopia and oscillopsia in the setting of superior oblique paresis and myokymia with persistent symptoms after initial superior oblique tuck. An alternative surgical approach consisting of superior oblique anterior one-third nasal tenectomy and contralateral inferior rectus recession resulted in marked improvement of oscillopsia associated with superior oblique myokymia while minimizing the risk of inducing downgaze diplopia often observed with superior oblique tenectomy.
Cranial nerve neuropathies: a rare manifestation of cat scratch disease.
Cranial nerve neuropathies represent a rare manifestation of cat scratch disease (CSD). Only a few case reports have been published, and the full clinical spectrum remains poorly characterized. We aimed to describe the clinical presentation, diagnostic approach, and prognosis of cat scratch disease (CSD)-associated cranial nerve neuropathies, a manifestation that is poorly characterized. Using data from a national CSD surveillance study, we identified patients with CSD-associated cranial neuropathies confirmed by serology and/or PCR for Bartonella henselae. Clinical, epidemiological, and imaging data were analyzed. Follow-up was conducted. Seven immunocompetent patients with cranial nerve neuropathies were identified among approximately 4100 CSD patients diagnosed over a 28-year period (1997–2025). Affected cranial nerves included the facial (n = 3), abducens (n = 2), oculomotor (n = 1), and glossopharyngeal (n = 1) nerves, the latter two not previously reported in patients with CSD. All patients reported cat exposure. Neuropathies were accompanied by other CSD-related features, including fever (71%), lymphadenitis (57%), neuroretinitis (43%), and encephalitis (14%). Three patients received antibiotic therapy and five were treated with systemic corticosteroids. Six patients fully recovered within a median of 4 weeks; one patient showed marked improvement after 3 months and was subsequently lost to follow-up. CSD-associated cranial neuropathies are rare and possibly underdiagnosed. Diagnostic clues include cat contact and concurrent CSD features such as fever, lymphadenopathy, or neuroretinitis. These findings are hardly observed in idiopathic cranial nerve palsies such as Bell’s palsy, for which guidelines recommend against routine serologic evaluation. Although outcomes are generally favorable, optimal treatment remains undefined. We suggest testing for B. henselae infection in patients with cranial neuropathies when CSD is suspected. Increased clinical awareness is warranted to facilitate timely diagnosis and management.
Ocular Myasthenia Gravis following strabismus surgery and presenting as refractory strabismus.
Ocular myasthenia gravis is a protean disorder and can present with myriad disorders of ocular motility. The diagnosis may not be obvious at presentation and strabismus surgery has occasionally been performed with unexpected outcomes. Strabismus surgery can be performed on patients with ocular myasthenia gravis who have stable ocular deviations, although outcomes may vary. We report two patients who were operated for strabismus and were diagnosed as ocular myasthenia gravis later, when classic signs appeared. The first patient underwent right medial rectus recession and left lateral rectus plication for a left sixth nerve palsy surgery. He developed recurrent strabismus and ptosis 3 months after surgery and was diagnosed as ocular myasthenia gravis on the basis of positive ice test, fatigue test and repetitive nerve stimulation test. He was started on a tapering regime of oral steroids and pyridostigmine. This reduced the deviations to a level correctable by prisms eventually becoming orthophoric in primary position. The second patient had a severe undercorrection of strabismus after large recess resect procedure on the right eye for large angle exotropia. Five months after surgery, he presented with right eye ptosis and a recurrence of strabismus. He tested positive for anti-acetylcholine receptor antibodies. The ptosis improved with oral steroids and pyridostigmine and he eventually went into a natural remission. The ocular deviation, however, remained unchanged. The emergence of ocular myasthenia in patients undergoing strabismus surgery is a rare occurrence but should be suspected in patients with unexpected outcomes after strabismus surgery.
Publicações recentes
Update on Congenital Cranial Dysinnervation Disorders (CCDDs).
Rare oculomotor nerve palsy after interventional treatment of anterior communicating artery aneurysm: A case report.
Isolated oculomotor nerve palsy following mild traumatic brain injury: diagnostic challenges and insights from High-Resolution MRI.
The p.Ile202Thr Substitution in TUBB2B Can Be Associated with Syndromic Presentation of Congenital Fibrosis of the Extraocular Muscles.
Oculomotor nerve palsy from unruptured cavernous internal carotid artery aneurysms: a case series and report of an anatomical variant.
📚 EuropePMCmostrando 199
Pediatric Cranial Nerve Palsies.
International ophthalmology clinicsUpdate on Congenital Cranial Dysinnervation Disorders (CCDDs).
International ophthalmology clinicsSelective Nasal Anterior Superior Oblique Tenectomy for the Treatment of Superior Oblique Myokymia.
Journal of binocular vision and ocular motilityCranial nerve neuropathies: a rare manifestation of cat scratch disease.
BMC infectious diseasesA Ruptured Tri-Lobulated ICA-PCom Aneurysm Presenting with Preserved Neurological Function: Case Report and Clinical-Anatomical Analysis.
Diagnostics (Basel, Switzerland)Ophthalmoplegia and vision loss in extrapulmonary tuberculosis with bilateral cavernous sinus involvement.
IDCasesIncidence, Clinician Misdiagnosis Rate, Radiologist Missed Diagnosis Rate, and Lesion Distribution of Isolated Medial Longitudinal Fasciculus Infarction: A Retrospective Study.
International journal of general medicineThe Hidden Cavernous Mystery Behind a Headache: A Case Report of Tolosa-Hunt Syndrome.
CureusA Rare Presentation of Guillain-Barré Syndrome: A Case Report and Literature Review.
CureusRare oculomotor nerve palsy after interventional treatment of anterior communicating artery aneurysm: A case report.
MedicineIsolated oculomotor nerve palsy following mild traumatic brain injury: diagnostic challenges and insights from High-Resolution MRI.
Emergency radiologyThe p.Ile202Thr Substitution in TUBB2B Can Be Associated with Syndromic Presentation of Congenital Fibrosis of the Extraocular Muscles.
GenesStrabismus fixus convergens secondary to protracted hydrocephalus.
BMJ case reportsOculomotor nerve palsy from unruptured cavernous internal carotid artery aneurysms: a case series and report of an anatomical variant.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of AustralasiaNeurosarcoidosis With Cranial Nerve Polyneuropathy: A Case Report Highlighting the Potential Role of Serial Systemic Immune-Inflammatory Indices (SSIIi).
CureusOcular Myasthenia Gravis following strabismus surgery and presenting as refractory strabismus.
StrabismusPeriocular Management of Pediatric Facial Nerve Palsy.
American journal of ophthalmologyTransformative Dental Care in Pediatric Moebius Syndrome: Bridging Oral Health and Systemic Management During Prolonged Hospitalization.
Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric DentistryIsolated congenital third nerve ophthalmoplegia due to potential neurovascular conflict of the posterior cerebral artery.
BMJ case reportsFacial reanimation in Moebius syndrome - 25-Year experience in treating bilateral facial paralysis.
Journal of plastic, reconstructive & aesthetic surgery : JPRASOcular neurolymphomatosis: a case report and systematic review of ocular cranial nerve neurolymphomatosis.
Orbit (Amsterdam, Netherlands)The Etiology of Moebius Syndrome-Making the Case for Animal Models.
International journal of molecular sciencesBotulinum Toxin Injection in Acute Sixth Nerve Palsy in a 1-Year-Old Child: Case Report, Management Strategy, and Review of Literature.
Romanian journal of ophthalmologySepto-optic dysplasia and gastroschisis: trends in birth prevalence and association with maternal age.
European journal of pediatricsBiological pathways leading to septo-optic dysplasia: a review.
Orphanet journal of rare diseasesRare Case with Pathogenic Variant in DHX16 Gene Causing Neuromuscular Disease and Oculomotor Anomalies.
International journal of molecular sciencesHorizontal gaze palsy with ipsilateral esotropia with substituted convergence in a child with medulloblastoma.
StrabismusThird nerve palsy as first presenting symptom of Guillain-Barre Syndrome spectrum clinical variant.
American journal of ophthalmology case reportsOcular ischaemic syndrome due to giant cell arteritis.
BMJ case reportsA Rare Guillain-Barré Syndrome Variant with Multi-Ganglioside Reactivity: A Case of Severe Cranial Nerve Involvement.
Revista de neurologiaPediatric isolated oculomotor nerve palsy induced by peduncular atypical teratoid/rhabdoid tumor: case report and literature review.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and StrabismusInverse Duane's retraction syndrome: rare presentation of orbital myocysticercosis.
StrabismusBiallelic NDUFA13 variants lead to a neurodevelopmental phenotype with gradual neurological impairment.
Brain communicationsIsolated oculomotor nerve palsy due to mesencephalic infarction diagnosed by ZOOM DWI.
BMC neurologyFeatures of myositis and myasthenia gravis in patients treated with immune checkpoint inhibitors: a multicentric, retrospective cohort study.
The Lancet regional health. EuropeSleep health of adults and children with Moebius syndrome.
Research in developmental disabilitiesMoebius syndrome and hypopituitarism: a case of multiple pituitary hormone deficiency and revision of the literature.
Journal of pediatric endocrinology & metabolism : JPEMTolosa-Hunt syndrome in children and adolescents: A systematic review.
HeadacheContralateral oculomotor nerve palsy associated with PHACES syndrome.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and StrabismusSuccessful outcome in synergistic divergence after unilateral lateral rectus recession and medial rectus resection.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and StrabismusManagement of Herpes Zoster Ophthalmicus with Optic Neuritis and Cavernous Sinus Involvement: A Case Report.
Ocular immunology and inflammationPupil sparing oculomotor nerve palsy with concomitant Horner syndrome as a presentation of mantle cell lymphoma relapse.
BMJ case reportsGalloway-Mowat syndrome with retinal involvement associated with a novel WDR73 variant: case report and review of the literature.
Ophthalmic geneticsOrbital Myositis after Herpes Zoster Ophthalmicus: A Case Report and a Narrative Review of the Literature.
Pathogens (Basel, Switzerland)Recurrent VI cranial nerve paralysis secondary to idiopathic cavernous sinus pachymeningitis: a case report.
Archivos de la Sociedad Espanola de OftalmologiaClinical, laboratory and neuroimaging profile of patient's cohort with septo-optic dysplasia treated at a pediatric university hospital.
Jornal de pediatriaClinical profile and outcomes in Tolosa-Hunt Syndrome; a systematic review.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of AustralasiaRare Case of Post-Traumatic Abducens-Oculomotor Nerve Synkinesis Exhibiting Unusual Ocular Motility.
The American journal of case reportsA rare case of isolated medial rectus palsy in a young female.
Medical journal, Armed Forces IndiaComplete Third Nerve Palsy: A Rare Occurrence in Fulminant IIH Case Report.
The NeurohospitalistParesis of the Oculomotor Nerve due to Neurovascular Conflict with Superior Cerebellar Artery.
Journal of neurological surgery. Part A, Central European neurosurgeryThrough their eyes: Navigating life with limited eyelid closure in patients with Moebius syndrome.
Journal of plastic, reconstructive & aesthetic surgery : JPRASMicrovascular Decompression for Oculomotor Nerve Palsy Due to Nonaneurysmal Neurovaslur Conflict: 5 Cases Report and Literature Review.
World neurosurgeryExploring the Impact of Genetics in a Large Cohort of Moebius Patients by Trio Whole Exome Sequencing.
GenesExploring Treatments for a Rare Guillain-Barré Variant: A Case Report of Miller-Fisher Syndrome.
CureusDuane syndrome associated with Rubinstein-Taybi syndrome type II.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and StrabismusA Rare Case of Adult-Onset Bilateral Nonspecific Orbital Inflammation (NSOI) With Concomitant Unilateral Third Cranial Nerve Palsy.
CureusClinical and genetic characteristics of Chinese patients with congenital fibrosis of the extraocular muscles.
Orphanet journal of rare diseasesIsolated unilateral ptosis as a complication of sinusitis: A case report and literature review.
Clinical case reportsExpanding the genetics and phenotypes of ocular congenital cranial dysinnervation disorders.
Genetics in medicine : official journal of the American College of Medical GeneticsHorizontal gaze palsy with progressive scoliosis: Further expanding the ROBO3 spectrum.
Annals of clinical and translational neurologyDuane syndrome in association with congenital disorder of glycosylation type Ig (ALG12-CDG).
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and StrabismusTemporal arteritis presenting as third nerve palsy - a case report and review of literature.
Rheumatology internationalClinical features and surgical management of traumatic acquired isolated superior rectus palsy.
European journal of ophthalmologyJoubert syndrome presenting bilateral peroneal neuropathies: A case report.
MedicineManagement of an older Marshall-Smith syndrome patient: a review of literature of MSS and craniosynostosis.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryTwo cases of Duane retraction syndrome with abnormal orbital structures.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and StrabismusRight-sided Herpes Zoster Ophthalmicus Complicated by Bilateral Third, Fourth, and Sixth Cranial Nerve Palsies and Syndrome of Inappropriate Antidiuretic Hormone Secretion.
Internal medicine (Tokyo, Japan)Successful surgical treatment of oculomotor palsy due to schwannoma of the cavernous sinus in a 7-year-old girl: a case report.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryIsolated Inferior Division Oculomotor Nerve Palsy as the First Manifestation of Human Immunodeficiency Virus and Syphilis Co-Infection: A Rare Case Report.
Neuro-ophthalmology (Aeolus Press)Oral findings and comprehensive dental management of Moebius syndrome: a systematic review.
BMC oral healthPhysiopathologic Bases of Moebius Syndrome: Combining Genetic, Vascular, and Teratogenic Theories.
Pediatric neurologyOculomotor nerve cavernous malformation: case report and operative video.
Acta neurochirurgicaMedial strabismus (esotropia) at rest associated with contralateral paramedian thalamic ischemic infarction in 2 dogs.
Journal of veterinary internal medicineDecision-Making in Clival Mass Lesions: Risk Factors for Malignant Disease and an Illustrative Case Example.
Journal of neurological surgery reportsOrbital Fibrotic Band as Cause of Monocular Elevation Deficiency.
Ophthalmic plastic and reconstructive surgeryRecurrence and long-term outcomes of Tolosa-Hunt syndrome.
Journal of neurologyTwo novel CHN1 variants identified in Duane retraction syndrome pedigrees disrupt development of ocular motor nerves in zebrafish.
Journal of human geneticsIsolated unilateral oculomotor palsy caused by pure midbrain infarction: a case report.
The International journal of neuroscienceTemporal lobe uncal herniation with contralateral superior cerebellar artery infarct.
Journal of forensic sciencesMoebius syndrome and gastroschisis-The second case of a rare association.
American journal of medical genetics. Part ARoss syndrome with chronic cough and RF positivity: a case report.
Acta neurologica TaiwanicaOptic nerve abnormalities in female-restricted Wieacker-Wolff syndrome by a novel variant in the ZC4H2 gene.
Ophthalmic geneticsNeurodevelopmental impairments in children with septo-optic dysplasia spectrum conditions: a systematic review.
Molecular autism[Clinical features and genetic analysis of a patient with type 2 neurofibromatosis manifested as oculomotor nerve palsy].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical geneticsA Novel De novo Heterozygous Mutation in the SON Gene Associated with Septo-optic Dysplasia: A New Phenotype.
NeuropediatricsA rare cause of intellectual disability: Novel mutations of NFIX gene in two patients with clinical features of Marshall-Smith syndrome and Malan syndrome.
International journal of developmental neuroscience : the official journal of the International Society for Developmental NeurosciencePostoperative Third Nerve Palsy after Endoscopic Endonasal Transsphenoidal Surgery for Pituitary Adenoma: Elucidating its Mechanism.
Neurology IndiaThe challenging management of Moebius syndrome using orthodontic camouflage: A case report.
Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric DentistryBilateral Oculomotor Ocular Neuromyotonia-A Rare Case Due to Nasopharyngeal Carcinoma Radiotherapy.
Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology SocietyClinical Features of Pituitary or Parasellar Tumor Onset with Cranial Nerve Palsy: Surgical Intervention Considerations.
World neurosurgeryRole of Fetal Magnetic Resonance Imaging in Differentiating Isolated Septal Agenesis from Septo-Optic Dysplasia: Case Study and Review.
Fetal diagnosis and therapyIs Guillain-Barre syndrome following chickenpox a parainfectious disease? A case report and literature review.
BMC neurologyAnti-Ri paraneoplastic neurological syndrome presenting with bilateral cranial nerve VI palsy and jaw dystonia-a distinctive syndrome within the anti-Ri spectrum? : Case report and literature review.
Wiener medizinische Wochenschrift (1946)Orbital leiomyoma presenting as inverse globe retraction syndrome: a unique presentation of a rare disease.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and StrabismusSurgical approach for traumatic chiasmal syndrome and complete third nerve palsy following severe head trauma.
BMJ case reportsElectrophysiology of ataxia-telangiectasia-like disorder 1.
Sudanese journal of paediatricsPoland-Möbius syndrome: a case report implicating a novel mutation of the PLXND1 gene and literature review.
BMC pediatricsClaude Syndrome in Childhood Associated with Probable Neuro-Behcet Disease.
NeuropediatricsBenedikt syndrome in a 74-year-old hypertensive woman: A case report.
Clinical case reportsA rare cause of pediatric oculomotor nerve palsy: neurobrucellosis.
HeliyonClinical and genetic characteristics of Chinese patients with congenital cranial dysinnervation disorders.
Orphanet journal of rare diseasesSupernumerary Extraocular Muscle: A Rare Cause of Atypical Restrictive Strabismus.
Medicina (Kaunas, Lithuania)Wildervanck syndrome: clinical case report.
Archivos argentinos de pediatriaEchoencephalography of Möbius sequence: A congenital cranial dysinnervation disorder with brainstem calcifications.
Journal of neuroimaging : official journal of the American Society of NeuroimagingAlternating adduction hypertropia as a rare presentation of midbrain hemorrhage.
Journal of neurologyDifficult intubation and postoperative aspiration pneumonia associated with Moebius syndrome: a case report.
BMC anesthesiologyDelineating septo-optic dysplasia.
Birth defects researchOculomotor nerve palsy in neurofibromatosis type 2.
Radiology case reportsCD20-positive subcutaneous panniculitis-like T-cell lymphoma presenting as polycranial neuropathy: A CARE-compliant case report and literature review.
MedicineAnti-disialosyl-immunoglobulin M chronic autoimmune neuropathies: a nationwide multicenter retrospective study.
European journal of neurologyA Case Report on a Unique Explanation for Headache With Ophthalmoplegia: The Tolosa-Hunt Syndrome.
CureusRecurrent Painful Ophthalmoplegic Neuropathy with Unilateral Oculomotor and Trochlear Nerve Palsy in an 8-year-old Girl.
Journal of binocular vision and ocular motility[Septo optic dysplasia plus: about a case].
The Pan African medical journalRecurrent Painful Ophthalmoplegic Neuropathy in an Adult Patient: A Case Report With Literature Review.
CureusBilateral enlargement of all extraocular muscles: a presenting ophthalmic sign of hematologic malignancy.
Orbit (Amsterdam, Netherlands)Abduction Deficit Mimicking Sixth Nerve Palsy due to Metastasis in Systemic Malignancy: Rare Case Report.
Middle East African journal of ophthalmology[A case of Coexistent Persistent Trigeminal and Hypoglossal Arteries Manifested with Neurovascular Compression Syndrome by Hypertension].
Brain and nerve = Shinkei kenkyu no shinpo[Claude syndrome: Incomplete third cranial nerve palsy and contralateral ataxia].
Medicina[Ophthalmic complications of endoscopic sinus surgery].
Vestnik oftalmologiiSurgical Management of Pre-Chiasmatic Intraorbital Optic Nerve Gliomas in Children after Loss of Visual Function-Resection from Bulbus to Chiasm.
Children (Basel, Switzerland)Incomplete Third Nerve Palsy Due to a Carotid-Cavernous Fistula.
The neurologistHypopituitarism and cranial nerve involvement mimicking Tolosa-Hunt syndrome as the initially presenting feature of diffuse large B-cell lymphoma: a case report.
BMC endocrine disordersPost-traumatic Oculomotor Nerve Palsy due to Intraneural Hemorrhage: A Case Report.
Neurology IndiaHorizontal Gaze Palsy and Progressive Scoliosis in Dizygotic Twins.
Journal of binocular vision and ocular motilityPost-COVID simultaneous onset of Graves' disease and ocular myasthenia gravis in a patient with a complex ocular motility impairment.
European journal of ophthalmologyA long-term survival case with proton beam therapy for advanced sphenoid sinus cancer with hypopituitarism.
International cancer conference journalA Case of Invasive Sphenoid Sinus Aspergillosis Presenting as Oculomotor Nerve Palsy in a Healthy Patient.
NMC case report journalSepto-optic dysplasia: Ophthalmological abnormalities in a series of 5 cases.
Archivos de la Sociedad Espanola de OftalmologiaFebrile episode unmasking neuropsychiatric systemic lupus erythematosus with lytic lesions caused by secondary autoimmune myelofibrosis: Case report.
MedicineBevacizumab-induced isolated oculomotor nerve palsy in glioblastoma multiforme.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy PractitionersImmunoglobulin G4-related disease of the cavernous sinus with orbit invasion - A case report.
Surgical neurology internationalOculomotor nerve schwannoma: case series and literature review.
Survey of ophthalmologyFlow diversion for internal carotid artery aneurysms with compressive neuro-ophthalmologic symptoms: clinical and anatomical results in an international multicenter study.
Journal of neurointerventional surgeryA severe case of Bosch-Boonstra-Schaaf optic atrophy syndrome with a novel description of coloboma and septo-optic dysplasia, owing to a start codon variant in the NR2F1 gene.
American journal of medical genetics. Part ARecurrent painful ophthalmoplegic neuropathy: a cause for recurrent third nerve palsy in a child.
BMJ case reportsRare presentation of sarcoidosis with optic neuropathy and third nerve palsy.
BMJ case reportsBilateral carotid cavernous fistula after trauma: a case report and literature review.
Chinese neurosurgical journalSplenogonadal fusion associated with Moebius and Poland syndromes: first case reported.
Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica[Paraneoplastic ophthalmopathies].
Journal francais d'ophtalmologieNeuromyelitis optica with brain stem involvement in a middle-aged Ethiopian woman: a case report and review of literature.
Journal of medical case reportsLarge sphenoid mucocele presenting with cranial neuropathies in a 10-year-old boy: case report and literature review.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryHerpes Simplex Virus-2 Meningoencephalitis With Abducens Nerve Palsy With Literature Review.
CureusDelayed oculomotor nerve palsy associated with a ruptured anterior communicating aneurysm: Case report.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of AustralasiaInverse Marcus Gunn jaw winking phenomenon: a rare inhibitory synkinesis.
Orbit (Amsterdam, Netherlands)Septo-Optic Dysplasia with Cerebellar Hemiagenesis: A Rare Congenital Malformation.
Neurology IndiaIsolated oculomotor nerve palsy secondary to acute sinusitis.
The journal of the Royal College of Physicians of EdinburghTransient oculomotor paralysis after cerebral angiography: A case report.
MedicineOcular neuromyotonia caused by a recurrent sphenoidal ridge meningioma.
Surgical neurology internationalVaried presentations of congenital ocular synkinesis: do they all fit congenital cranial dysinnervation disorder spectrum?
Arquivos brasileiros de oftalmologiaDisorders of the Fourth Cranial Nerve.
Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology SocietyThe phenotypic spectrum associated with OTX2 mutations in humans.
European journal of endocrinologyA 7-year old female with arthrogryposis multiplex congenita, Duane retraction syndrome, and Marcus Gunn phenomenon due to a ZC4H2 gene mutation: a clinical presentation of the Wieacker-Wolff syndrome.
Ophthalmic geneticsOculomotor Paresis with Cyclic Spasms in Chinese Populations: A Review of the Chinese Literature and a Case Report.
Pediatric neurosurgeryCompressive optic neuropathy (CON) in Graves' disease caused by hypertrophy of levator and superior rectus muscles: A case report.
MedicineThe epidemiology of Moebius syndrome in Italy.
Orphanet journal of rare diseasesIsolated third cranial nerve palsy as the first presentation of multiple myeloma.
BMJ case reportsA rare case of orbital myositis.
Journal of Ayub Medical College, Abbottabad : JAMCEarly Recurrence of an Infantile Endodermal Oculomotor Nerve Cyst following Surgical Fenestration: A Case Report.
Pediatric neurosurgeryPostpartum Recovery From Meningioma-Related Oculomotor Palsy.
Obstetrics and gynecologyPseudo-Duane retraction syndrome after orbital myositis.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and StrabismusVariant types of Duane retraction syndrome: synergistic divergences and convergences.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and StrabismusAdie-Holmes syndrome associated with COVID-19 infection: A case report.
Indian journal of ophthalmologyMasquerading Guillain-Barré syndrome: uncommon, in-hospital presentation of Miller-Fisher syndrome shadowed by secondary diseases.
BMJ case reportsTolosa-Hunt Syndrome Misdiagnosed as Surgical Complication After Frontal Balloon Sinuplasty.
The Journal of craniofacial surgeryA rare association of type 2 Duanes retraction syndrome with arthrogryposis multiplex congenita.
StrabismusDevelopmental delay with hypotrophy associated with homozygous functionally relevant REV3L variant.
Journal of molecular medicine (Berlin, Germany)Acute Complete Oculomotor Nerve Palsy in a Young Male Due to a Skull Base Myofibroma.
Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology SocietySinus Arrest and Bradycardia Induced by Carotid Baroreceptor Reflex Activation during Rotational Angiography: A Case Report.
Journal of neuroendovascular therapyIsolated contralateral abducens palsy in direct carotid-cavernous fistula.
BMJ case reportsA Rare Case of Oculomotor Nerve Palsy after Endovascular Treatment in a Patient with Internal Carotid Artery Dissection.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke AssociationA Presentation of Pediatric Sjögren's Syndrome with Abducens Nerve Palsy.
NeuropediatricsKIF21A pathogenic variants cause congenital fibrosis of extraocular muscles type 3.
Ophthalmic geneticsIsolated Oculomotor Nerve Palsy - A Rare Initial Manifestation of Tuberculous Meningitis.
The Journal of the Association of Physicians of IndiaNasopharyngeal B-cell lymphoma with pan-hypopituitarism and oculomotor nerve palsy: a case report and review of the literature.
BMC endocrine disordersA novel homozygous frameshift mutation in the DCC gene in a Pakistani family with autosomal recessive horizontal gaze palsy with progressive scoliosis-2 with impaired intellectual development.
American journal of medical genetics. Part AGlioblastoma multiforme with oculomotor nerve involvement: case report and literature review.
British journal of neurosurgeryOcular neuromyotonia of the right third cranial nerve.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and StrabismusThird Cranial Nerve Palsy Presenting with Unilateral Diplopia and Strabismus in a 24-Year-Old Woman with COVID-19.
The American journal of case reportsAnkyloglossia Superior Syndrome With Complex Craniofacial Anomalies: Case Report and Literature Review.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationSkull Base Metastasis of Breast Cancer With Oculomotor and Trochlear Nerve Palsy.
Ear, nose, & throat journalDevelopment, behaviour and sensory processing in Marshall-Smith syndrome and Malan syndrome: phenotype comparison in two related syndromes.
Journal of intellectual disability research : JIDRReview of the MRI brain findings of septo-optic dysplasia.
Clinical radiologyA Rare Intracranial Collision Tumor of Meningioma and Metastatic Uterine Adenocarcinoma: Case Report and Literature Review.
World neurosurgeryPosterior communicating artery infundibulum with oculomotor nerve palsy treated with microvascular decompression: a case report and 2-dimensional technical operative video.
British journal of neurosurgeryDifferential Diagnosis of Acquired Esotropia in the Elderly.
Klinische Monatsblatter fur AugenheilkundeA Case of Meningioma Originating from the Oculomotor Nerve.
World neurosurgeryFatal high-grade skull osteosarcoma 30 years following radiotherapy for Cushing's disease.
Endocrinology, diabetes & metabolism case reportsA Case of Recurrent Painful Ophthalmoplegic Neuropathy Successfully Treated with Beta-blocker Eye Drop Instillation.
Neuro-ophthalmology (Aeolus Press)Plus-minus lid syndrome with ataxia and severe apathy-A rare manifestation of midbrain infarct.
Journal of postgraduate medicineTonic pupil caused by adenoid cystic carcinoma versus postradiation changes to the ciliary ganglion.
BMJ case reportsSixth cranial nerve palsy secondary to compression by dolichoectatic vertebrobasilar artery.
BMJ case reportsFronto-orbital advancement in a patient with Marshall-Smith syndrome: a case report and review of the literature.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryMutation in ROBO3 Gene in Patients with Horizontal Gaze Palsy with Progressive Scoliosis Syndrome: A Systematic Review.
International journal of environmental research and public healthTUBB3 E410K syndrome: Case report and review of the clinical spectrum of TUBB3 mutations.
American journal of medical genetics. Part ASepto-optic dysplasia with fovea plana: A case report.
European journal of ophthalmologyThe oculomotor neurovascular conflict: Literature review and proposal of management.
Clinical neurology and neurosurgeryThe rare phenomenon of Marcus-Gunn jaw winking without ptosis: Report of 14 cases and review of the literature.
Indian journal of ophthalmologyIsolated Oculomotor Nerve Palsy in Takayasu Arteritis-A Rare Complication.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseasesAssociações
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Pediatric Cranial Nerve Palsies.
- Update on Congenital Cranial Dysinnervation Disorders (CCDDs).
- Selective Nasal Anterior Superior Oblique Tenectomy for the Treatment of Superior Oblique Myokymia.
- Cranial nerve neuropathies: a rare manifestation of cat scratch disease.
- Ocular Myasthenia Gravis following strabismus surgery and presenting as refractory strabismus.
- Rare oculomotor nerve palsy after interventional treatment of anterior communicating artery aneurysm: A case report.
- Isolated oculomotor nerve palsy following mild traumatic brain injury: diagnostic challenges and insights from High-Resolution MRI.
- The p.Ile202Thr Substitution in TUBB2B Can Be Associated with Syndromic Presentation of Congenital Fibrosis of the Extraocular Muscles.
- Oculomotor nerve palsy from unruptured cavernous internal carotid artery aneurysms: a case series and report of an anatomical variant.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:98685(Orphanet)
- MONDO:0001309(MONDO)
- GARD:19544(GARD (NIH))
- Variantes catalogadas(ClinVar)
- Busca completa no PubMed(PubMed)
- Artigo Wikipedia(Wikipedia)
- Q1723331(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
