Pênfigo vulgar

Autoimmune Blistering Diseases Study

NCT02753777

Periodontal Status and Disease Severity in Pemphigus Vulgaris Patients

NCT07384221

A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV)

Fase II

NCT04422912

Open-label Single-Center Study to Evaluate the Safety and Efficacy of Combining Rituximab and AB-101 in B-cell Associated Autoimmune Diseases.

NCT06581562

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

NCT05635266

NCT02753777 · Autoimmune Blistering Diseases StudyRecrutando

🟢 Recrutando agora

5 pesquisas recrutando participantes. Converse com seu médico sobre a possibilidade de participar.

NCT07384221 · Periodontal Status and Disease Severity in Pemphigus Vulgari…Recrutando

NCT04422912 · A Phase 1/2, Open-label, Safety and Dosing Study of Autologo…Recrutando

PHASE1, PHASE2

NCT06581562 · Open-label Single-Center Study to Evaluate the Safety and Ef…Recrutando

PHASE1

NCT05635266 · Tissue Repository Providing Annotated Biospecimens for Appro…Recrutando

Outros ensaios clínicos

45 ensaios clínicos encontrados, 8 ativos.

Distribuição por fase

NCT06971172 · Low-level Laser Therapy on Oral Pemphigus Vulgaris Patients.Em breve

NA

NCT06863454 · Trichoscopy as a Monitoring Tool for Activity and Remission …Em breve

NCT06663943 · A Randomized Study on Pemphigus Treatment With Humanized CD3…Em breve

PHASE1, PHASE2

NCT07461103 · Effect of Topical Insulin on Healing Rate of Pemphigus Lesio…Concluído

PHASE2

NCT07428915 · Evaluating Legit.Health Plus Support for Improving Diagnosis…Concluído

NCT05000216 · COVID-19 Booster Vaccine in Autoimmune Disease Non-Responder…Encerrado

PHASE2

NCT04598477 · A Study to Assess the Long-term Safety and Efficacy of a Sub…Encerrado

PHASE3

NCT06846255 · Comparing DCP and DAP for Pemphigus VulgarisConcluído

PHASE4

NCT06654817 · Efficacy and Safety Evaluation of Anti-CD20 Monoclonal Antib…Concluído

NCT04598451 · A Study to Assess the Efficacy and Safety of a Subcutaneous …Concluído

PHASE3

NCT03239470 · Polyclonal Regulatory T Cells (PolyTregs) for PemphigusEncerrado

PHASE1

NCT04540133 · Dexamethasone Solution and Dexamethasone in Mucolox™Concluído

PHASE2

NCT06167408 · Identifying Factors Influencing In-Hospital Relapse in Pemph…Concluído

NCT03762265 · A Study of PRN1008 in Patients With PemphigusEncerrado

PHASE3

NCT05338112 · Role of Tzanck Smear in Determining Pemphigus Vulgaris Disea…UNKNOWN

Ver todos no ClinicalTrials.gov

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Publicações mais relevantes

Timeline de publicações

1.841 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 1.841

#1

Iatrogenic Upper Gastrointestinal Bleeding Following Nasogastric Tube Insertion in a Patient with Pemphigus Vulgaris.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2026 Jan 05

Cite this article as: Ketenci YB, .akır A, Yılmaz GA, Avcıoğlu U, Demir.z H, Akca M. Iatrogenic upper gastrointestinal bleeding following nasogastric tube insertion in a patient with pemphigus vulgaris. Turk J Gastroenterol. 2026;37(3):403-405.

#2

Caspase-activation powers anti-Desmoglein 3-induced acantholysis in human epidermis.

Cell death discovery2026 Feb 19

Pemphigus vulgaris (PV) is a life-threatening autoimmune blistering disease caused by circulating autoantibodies against desmoglein (Dsg) 1 and Dsg 3. Whether acantholysis in PV results exclusively from antibody binding to Dsgs or involves additional factors remains controversial. Given that Fas-Ligand (FasL), an activator of apoptotic caspase-8, is increased in the serum and the skin of patients with PV, we investigated the role of caspases in anti-Dsg3-mediated acantholysis using both ex vivo and in vitro models. Our results demonstrated that anti-Dsg3 antibodies induced acantholysis ex vivo in the absence of caspase activation, primarily through the redistribution of Dsg3 to intracellular compartments. FasL-induced caspase activation led to a synergistic amplification of anti-Dsg3-mediated loss of cell adhesion by promoting Dsg3 cleavage. This dual mechanism provides new insights into the disease heterogeneity of PV.

#3

[Value of direct immunofluorescence in the diagnosis of oral mucosal pemphigus vulgaris: A retrospective study based on multi-index combined analysis].

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences2026 Feb 18

To clarify the diagnostic efficacy of various diagnostic methods through multi-index combined analysis, and to explore the core diagnostic value of direct immunofluorescence (DIF) in oral mucosal pemphigus vulgaris (PV). A total of 53 patients with confirmed oral mucosal PV were included, retrospectively. Their data of DIF, histopathology, serum enzyme-linked immunosorbent assay (ELISA) and clinical diagnosis were systematically analyzed, and diagnostic efficacy of each method was evaluated using indicators, such as sensitivity, specificity, and area under curve (AUC) of the receiver operating characteristic (ROC) curve. The results showed that among the 53 patients, middle-aged and elderly females were predominant, the buccal mucosa was the most common involved site, and most patients had a history of blistering. The positive rate of DIF was 96.23%, mainly manifested as a reticular fluorescent deposition between epithelial spinous cells, demonstrating the highest diagnostic value with a sensitivity of 96.23%, specificity of 100.00%, and AUC of 0.981. Histopathology ranked second, with a sensitivity of 94.34%, a specificity of 100.00%, and an AUC value of 0.972. The ELISA test had a sensitivity of 82.61%, a specificity of 82.35%, and an AUC value of 0.825. Although the sensitivity of clinical diagnosis was acceptable, its specificity was relatively low. Additionally, DIF exhibited complementarity with histopathology, ELISA, and clinical diagnosis, and combined testing could improve diagnostic accuracy. DIF is the "gold standard" for the diagnosis of oral mucosal PV. A comprehensive diagnostic workflow of "clinical manifestation-DIF-histopathology-ELISA" is proposed. This integrated diagnostic system not only significantly improves the accuracy of oral mucosal PV diagnosis but also aligns with the core principles of precision medicine, providing a basis for indivi-dualized treatment. 基于多指标联合分析，探讨直接免疫荧光(direct immunofluorescence，DIF)对口腔黏膜寻常型天疱疮(pemphigus vulgaris，PV)的诊断效能。回顾性分析53例确诊口腔黏膜PV的患者，收集患者临床资料及DIF、组织病理学、血清学酶联免疫吸附试验(enzyme-linked immunosorbnent assay，ELISA)检测结果，采用灵敏度、特异度、受试者工作特征(receiver operating characteristic，ROC)曲线的曲线下面积(area under curve，AUC)等指标评估各方法的诊断效能。患者以中老年女性为主，颊黏膜为最常见受累部位，大部分患者伴有起疱史。DIF检测的阳性率为96.23%，主要表现为上皮棘细胞间网状绿色荧光沉积，其诊断价值最高，灵敏度为96.23%，特异度为100.00%，AUC值为0.981；组织病理学次之，灵敏度为94.34%，特异度为100.00%，AUC值为0.972；ELISA检测的灵敏度为82.61%，特异度为82.35%，AUC值为0.825。DIF与组织病理学、ELISA及临床诊断具有互补性，联合检测可提高诊断准确性。 DIF是诊断口腔黏膜PV的核心指标，建议采用“临床表现-DIF-组织病理学-ELISA”综合诊断流程；该综合诊断体系不仅能显著提升口腔黏膜PV诊断的精准度，也契合了精准医疗的核心理念，可为个性化治疗提供依据。

#4

3D organotypic skin models recapitulate autoantibody-driven pemphigus pathomechanisms and targeted therapeutic response.

Science advances2026 Jan 09

Advanced three-dimensional (3D) tissue models that recapitulate autoimmune disease progression can enable mechanistic studies and accelerate the development of targeted therapies with reduced reliance on systemic immunosuppression. Here, we present a dynamic biofabrication strategy combining 3D bioprinting and cell self-organization to create multilayered skin constructs with a stratified epidermis atop a vascularized, fibroblast-remodeled dermis. This platform reconstitutes native skin architecture to model pemphigus vulgaris, an autoantibody-driven blistering disorder. Tightly reassembled keratinocytes form cell-cell adhesions that replicate pathogenic antibody-induced disruption of the epidermal barrier, while embedded vasculature and fibroblasts shape dermal barriers that regulate molecular diffusion. We demonstrate that these tissue barriers define disease phenotypes and therapeutic responses by modulating antibody and drug penetration. As proof of concept, we quantitatively evaluate epidermal growth factor receptor-targeted inhibitors by measuring individual cell-cell junction integrity and applying machine learning-assisted image texture analysis. This organotypic skin model provides a physiomimetic testbed for precise investigation of autoimmune pathogenesis and high-throughput screening of targeted therapeutic agents.

#5

Epithelial Barrier Diseases Among Adult Patients With Seborrheic Dermatitis.

JAMA dermatology2026 Jan 01

The epithelial barrier theory (EBT) proposes that epithelial barrier disruption is implicated in the development of skin, respiratory, gastrointestinal, and ocular diseases (epithelial barrier diseases, or EBDs). There is a need to better understand the relationship between seborrheic dermatitis and EBDs, and we hypothesize that seborrheic dermatitis, characterized by epithelial barrier dysfunction, is associated with increased frequency of other EBDs. To explore the association between seborrheic dermatitis and EBDs. This retrospective cohort study used a large US administrative claims database, which included data collected from multiple health care centers and patient care settings across the US from January 1, 2016, through June 30, 2022. This study consisted of patients aged 18 years and older at enrollment, with at least 1 year of continuous enrollment, and with a minimum of 2 visits on unique days to a medical professional. The mean (SD) patient follow-up time was 3.46 (1.80) years with a total follow-up of more than 70 million person-years. Individuals with missing data for demographic covariates, including age, sex, and division (ie, billing region), were excluded. Data were analyzed from January to September 2025. Diagnosis of seborrheic dermatitis at any point during the observation period. Diagnosis of an EBD at any point during the observation period. Of 20 274 189 patients, 733 776 (3.62%) had seborrheic dermatitis (median [IQR] age, 62.63 [41.53-70.55] years; 54.7% female). Using adjusted models, seborrheic dermatitis was positively associated with atopic dermatitis (odds ratio [OR], 3.21; 95% CI, 3.18-3.24), alopecia areata (OR, 4.02; 95% CI, 3.93-4.11), contact dermatitis (OR, 2.25; 95% CI, 2.23-2.26), psoriasis (OR, 3.26; 95% CI, 3.23-3.29), rosacea (OR, 4.52; 95% CI, 4.49-4.56), hidradenitis suppurativa (OR, 1.63; 95% CI, 1.58-1.68), chronic spontaneous urticaria (OR, 1.35; 95% CI, 1.33-1.37), pemphigus vulgaris (OR, 1.48; 95% CI, 1.31-1.69), bullous pemphigoid (OR, 1.60; 95% CI, 1.51-1.70), rhinosinusitis (OR, 1.24; 95% CI, 1.24-1.25), celiac disease (OR, 1.36; 95% CI, 1.32-1.39), irritable bowel syndrome (OR, 1.32; 95% CI, 1.31-1.33), ocular allergy (OR, 1.39; 95% CI, 1.37-1.41), and dry eye (OR, 1.48; 95% CI, 1.48-1.49) and was negatively associated with chronic obstructive pulmonary disease (OR, 0.72; 95% CI, 0.71-0.72) and pulmonary hypertension (OR, 0.70; 95% CI, 0.69-0.71). These findings support the EBT as a shared driver in the pathogenesis of seborrheic dermatitis and other diverse EBDs and encourage further investigation into the underlying mechanisms of disease pathogenesis.

Publicações recentes

Nature's Bandage: A Memorable Rescue of Severe Pemphigus Vulgaris in a Resource-Limited Setting.

Clin Exp Dermatol2026 Apr 15

Kaposi Sarcoma Associated with Pemphigus Vulgaris in the Setting of Immunosuppressive Therapy: Case Report and Review of Literature.

Case Rep Dermatol2026 Jan-Dec

Critical analysis of pemphigus vulgaris in pregnancy.

Front Immunol2026

Single amino acid substitutions modulate the function of α9α10 nicotinic acetylcholine receptor.

Int J Biol Macromol2026 Apr 9

Lesion visibility and localization as predictors of social appearance anxiety in Pemphigus vulgaris: a case-control study.

Psychol Health Med2026 Apr 10

Ver todas no PubMed

📚 EuropePMC2.989 artigos no totalmostrando 192

European journal of dermatology : EJD

Bullous pemphigoid and Graves' disease developing during prolonged remission of pemphigus vulgaris.

Actas dermo-sifiliograficas

Experience with rituximab in patients with pemphigus vulgaris and hepatitis B.

Clinical, cosmetic and investigational dermatology

A Single-Center Profile of Pemphigus in China: Significant Diagnostic Delay and Evolving Treatment Patterns.

Diagnostic Delay in Desquamative Gingivitis: An Observational Cohort Study.

Oral diseases

Pemphigus Vulgaris With an Elevated Faecal Calprotectin Mimicking Inflammatory Bowel Disease: A Case Report.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology

Iatrogenic Upper Gastrointestinal Bleeding Following Nasogastric Tube Insertion in a Patient with Pemphigus Vulgaris.

International journal of molecular medicine

IL‑37/IL‑1R8 blocks keratinocyte acantholysis via suppressing ADAM17/EGFR.

Clinical and experimental dermatology

Pesticide Exposure as a Risk Factor for Pemphigus Vulgaris: Findings from a Case-Control Study conducted in Liguria, Italy.

Clinical and experimental dermatology

Pemphigus Vegetans: Insights from a systematic review of the literature.

Acta dermatovenerologica Croatica : ADC

What has Better Diagnostic Accuracy in Pemphigus? Direct Immunofluorescence of Plucked Hair, Oral Scrapes or Tzanck Smears!

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

Diagnostic Accuracy of Anti-Desmoglein 1 and 3 Antibodies by Enzyme-Linked Immunosorbent Assay (ELISA) in Pemphigus Vulgaris.

Could vector-derived cadherin mimicry contribute to pemphigus vulgaris? An immunogenetic and in silico study involving HLA-DRB104:02 and 14:01.

Case Report: Pemphigus following COVID-19 mRNA vaccination: two cases achieving long-term remission without relapse.

Autoimmune Bullous Diseases: Therapeutic Update.

Drugs

A case of juvenile pemphigus vulgaris effectively treated with dupilumab.

Dermatology online journal

Corticosteroid-induced central serous chorioretinopathy in a pemphigus vulgaris patient.

Dermatology online journal

Non-surgical treatment options for gingival recession: a dermatologic perspective.

A Specific Signature of Circulating Free Fatty Acid Discriminates Bullous Pemphigoid From Pemphigus Vulgaris and Healthy Controls.

Experimental dermatology

Caspase-activation powers anti-Desmoglein 3-induced acantholysis in human epidermis.

Cell death discovery

Pemphigus Vulgaris Mimicking Behçet's Syndrome With Oral and Vulvar Ulcers: A Case Report.

The Changing Trends in the Incidence and Clinical Presentation of Immunobullous Disorders Before and During the COVID-19 Era in a Tertiary Healthcare Centre in Andhra Pradesh.

Optimizing Local Treatment in Pemphigus and Pemphigoid: Current Evidence and Unmet Needs.

American journal of translational research

Dihydroartemisinin attenuates pemphigus vulgaris by regulating Dsg3 and the TLR9/NF-κB pathway.

Correlation of platelet-related parameters and autoantibodies in patients with autoimmune bullous diseases.

Laboratory medicine

Anti-Desmoglein 3 Avidity Correlates Better With Pemphigus Vulgaris Severity Than Anti-Desmoglein 3 Concentration.

Unmasking: paronychia as the hidden face of pemphigus.

Skin health and disease

Immunity, inflammation and disease

Navigating the Complexities of Pemphigus Vulgaris: A Comprehensive Iranian Study.

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences

[Value of direct immunofluorescence in the diagnosis of oral mucosal pemphigus vulgaris: A retrospective study based on multi-index combined analysis].

European journal of dermatology : EJD

Telitacicept in combination with systemic steroid therapy in a patient with refractory pemphigus vulgaris and tuberculosis: a case report.

Medicina (Kaunas, Lithuania)

An Update on Pemphigus Vulgaris in Pregnancy and Neonates: Management Options and Our Clinical-Laboratory Experience.

The Annals of otology, rhinology, and laryngology

Autoimmune Disorders Affecting the Larynx: Review of Laryngoscopic Findings and Approach to Multidisciplinary Management.

Pemphigus Vulgaris Successfully Treated with Belimumab: A Case Report.

Signalling in pemphigus vulgaris: shedding light on the protein kinase C conundrum.

Pemphigus vegetans successfully treated with systemic corticosteroid and rituximab: a rare case report with 15-month follow-up and literature review.

Journal of cutaneous medicine and surgery

Development of Autoimmune Bullous Disorders in Patients Exposed to Radiation Therapy: A Systematic Review.

Dermatology (Basel, Switzerland)

Clinical Phenotype Transition in Pemphigus May Suggest Undertreatment with Rituximab: Findings from a Retrospective Single-Centre Analysis of Relapsed Patients.

Bullous Diseases in the Perioperative Setting: Anesthetic Considerations.

Pemphigus Revealing Profound Hypothyroidism: A Rare Association.

Vulgar Verruca or Seborrheic Keratosis: A Clinical Challenge in Tattooed Skin.

Pemphigus foliaceus transforming to pemphigus vulgaris: a case report.

Frontiers in medicine

Oral Microbial Dysbiosis and Pathogenic Functional Shifts in Mucosa-Dominant Pemphigus Vulgaris and Low-Risk Mucous Membrane Pemphigoid.

Oral diseases

Mechanistic and systemic perspectives on TWEAK in pemphigus vulgaris.

Anais brasileiros de dermatologia

Comparing the genetic and serum expression of LL-37 Antimicrobial Peptide in pemphigus vulgaris and pemphigus foliaceus patients.

Anais brasileiros de dermatologia

BLyS/APRIL dual inhibition by telitacicept for refractory pemphigus vulgaris combined with hepatocellular cancer.

Esophagitis Dissecans Superficialis Associated With Mucosal Pemphigus vulgaris: A Rare and Underrecognized Clinical Presentation.

3D organotypic skin models recapitulate autoantibody-driven pemphigus pathomechanisms and targeted therapeutic response.

Science advances

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)

Noninvasive Imaging Techniques as Modern Diagnostic Tools in Desquamative Gingivitis: Focus on RCM, OCT, and LC-OCT.

Persistence of anti-Desmoglein 3 Antibodies in Patients with Pemphigus Vulgaris in Clinical Remission is Associated with Restricted Isotype Diversity and Desmoglein 3 Ectodomain Recognition.

American journal of clinical dermatology

Emerging Treatments in Pemphigus: Is Healing an Achievable Goal?

Clinical correlation of anti-desmoglein antibody dynamics in pemphigus treated with rituximab.

Isolated perineal plaque as the initial presentation of pemphigus vulgaris.

Rituximab resistant pemphigus vulgaris successfully treated with obinutuzumab.

Acantholytic Acanthoma Arising in Severely Photodamaged Skin: A Case Report.

Oral surgery, oral medicine, oral pathology and oral radiology

Radiotherapy-induced pemphigus vulgaris: a challenging case of extensive mucocutaneous ulcerations and literature review.

Dermatology (Basel, Switzerland)

Clinical and Immunological Outcomes of Rituximab Therapy in Pemphigus: A Prospective Observational Study.

Cytomorphological Spectrum and Diagnostic Utility of Tzanck Smear Cytology in Vesiculobullous Skin Lesions: A Cross-Sectional Study From a Tertiary Care Center in Eastern Uttar Pradesh, India.

A systematic review of therapeutic and paradoxical roles of tumor necrosis factor α inhibitors in autoimmune blistering diseases.

Inflammopharmacology

Rituximab-Based Management of Autoimmune Blistering Diseases: A Case Series Highlighting Ocular and Systemic Presentations.

A recalcitrant case of pemphigus treated with inebilizumab.

Direct Immunofluorescence in Immunobullous Disorders of Skin With Histopathological Correlation Among Patients Attending a Tertiary Care Center.

Strongyloides stercoralis Hyperinfection in Pemphigus Vulgaris: A Neglected Preventable Fatality.

Acta medica portuguesa

Case reports in dermatology

Pemphigus Vulgaris Mimicking Dyshidrotic Eczema: A Case Report.

Real-world outcomes with rituximab vs. conventional therapy in pemphigus vulgaris: a single-center Romanian cohort.

Frontiers in medicine

Medicina (Kaunas, Lithuania)

Sex-Specific Autoimmune Comorbidity Patterns in Pemphigus Vulgaris and Bullous Pemphigoid: A Bicenter Retrospective Case-Control Study.

Healthcare (Basel, Switzerland)

Patient-Reported Outcomes on Quality of Life in Older Adults with Oral Pemphigus.

The American Journal of dermatopathology

A Rare Case of Pemphigus Vulgaris With Esophageal Involvement: Spontaneous Expulsion of a 50-cm Mucosal Lumenoid Fragment.

Desquamative Gingivitis and the Oral Microbiome: Insights into Immune-Microbial Interactions in Mucosal Inflammation.

Dentistry journal

The Journal of dermatology

Updates in Pathogenesis of Pemphigus Vulgaris.

The Australasian journal of dermatology

Ultralow Dose Rituximab Combined With IVIG Is Safe and Effective in Pemphigus Vulgaris: Single-Center Review of 24 Patients.

[The role of KLF5 in cell adhesion and novel therapeutic approaches for pemphigus vulgaris].

Medecine sciences : M/S

Successful Treatment of Refractory Severe Pemphigus With Telitacicept as Adjunctive Therapy: Two Case Reports.

Role of protein kinase C subtype-specific signalling in regulating adhesion in human keratinocytes and skin in pemphigus.

Association of dietary diversity score and severity of pemphigus vulgaris: a cross-sectional study.

BMC nutrition

Efficient On-Column Removal of Endotoxin from Immunoglobulins Such as AK23.

Current protocols

Tumour necrosis factor-like weak inducer of apoptosis (TWEAK) is associated with inflammation and disease severity in pemphigus.

Epithelial Barrier Diseases Among Adult Patients With Seborrheic Dermatitis.

JAMA dermatology

Stem cell research & therapy

Apremilast improves cardiomyocyte cohesion and arrhythmia in different models for arrhythmogenic cardiomyopathy.

Boom or Bust: Clinical Trials in Pemphigus and Other B-Cell-Mediated Autoimmune Diseases.

A rare case report: retroperitoneal dedifferentiated liposarcoma associated with paraneoplastic pemphigus.

Frontiers in surgery

Apremilast for Oral Mucosal-Predominant Resistant Pemphigus Vulgaris: A Promising Adjunctive Treatment.

Oral diseases

Journal of dermatological science

Bead aggregation assays with desmoglein and desmocollin for the evaluation of disease activity in pemphigus.

Coexistence of Psoriasis and Pemphigus: A Case Report of Pemphigus Vulgaris With a Review of the Literature.

Clinical case reports

The Australasian journal of dermatology

Misleading Hepatitis B Serology Following Intravenous Immunoglobulin Treatment for Pemphigus Vulgaris.

Journal of clinical medicine

Eight Years of Follow-Up of Rituximab in Pemphigus Vulgaris and Foliaceus at a Single Center: Assessing Efficacy and Safety in Light of Several Factors.

The association between aromatic amino acids consumption and the severity of pemphigus vulgaris: a cross-sectional study.

Scientific reports

Ofatumumab for the management of refractory pemphigus vulgaris: A case series.

JAAD international

Journal of inflammation research

Crosstalk Between Keratinocytes and T Cells in Ulcerative Oral Mucosal Diseases: Mechanisms of Epithelial Dysfunction and Therapeutic Perspectives.

Science translational medicine

Conversion of pathogenic T cells into functionally stabilized Treg cells for antigen-specific immunosuppression in pemphigus vulgaris.

Journal of the American Academy of Dermatology

Biologic therapies for dermatologic emergencies: A comprehensive review.

Digestive diseases and sciences

Esophageal Severe Manifestation of Pemphigus Vulgaris.

Natural autoantibodies and their functional therapeutic roles in intravenous immunoglobulin.

Frontiers in aging

Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere

[Pemphigus vulgaris - a case report].

Introducing human 3D skin models as a new serological diagnostic tool for severe autoimmune bullous diseases.

Questionnaire Survey on Enterococcus faecalis-2001 Supplementation in 137 Patients With Oral Diseases at Two Facilities.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology

Pemphigus Vulgaris Scoring Systems: A Scoping Review.

Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995)

Desquamative Gingivitis: Medical and Surgical Management of Oral Lesions.

Taking aim at autoimmunity-Antigen-Fc constructs for mucosal pemphigus hit the mark.

Science immunology

SERPINB5/TGF-β signaling modulates desmoplakin membrane localization and ameliorates pemphigus vulgaris skin blistering.

JCI insight

Journal of the American Academy of Dermatology

Comparing combination and single-agent therapy for the treatment of pemphigus: A retrospective cohort study.

Mucous membrane pemphigoid with ocular involvement in a patient diagnosed previously with mucosal-dominant pemphigus vulgaris: A case report.

Deep Analysis of Desmoglein-3-Reactive CD4+ T Cells in Pemphigus Vulgaris Reveals a Type 17/Type 2 T-Cell Signature.

Minerva dental and oral science

Are the dermatological cut-off values of commercially available ELISAs for BP180-NC16A appropriate when applied for diagnosis of oral mucous membrane pemphigoid?. Results of a preliminary study.

Clinical Insights of Kaposi's Varicelliform Eruption Associated with Underlying Primary Dermatoses- A Case Series from Hadoti Region of Rajasthan.

Indian journal of medical microbiology

Species identification and antifungal susceptibility pattern of oral Candida isolates in pemphigus vulgaris: results from a case-control study.

Herpes Simplex Virus Type-1 Infection as a Trigger for Pemphigus Vulgaris.

Science translational medicine

Antigen-Fc fusion therapy reduces severity of a model of pemphigus vulgaris without systemic immunosuppression.

Clinical, cosmetic and investigational dermatology

Tofacitinib as a Novel Therapeutic Option for Pemphigus Vulgaris: A Case Report and Mechanistic Insights.

NPJ Regenerative medicine

Desmoglein-driven dynamic signaling in pemphigus vulgaris: a systematic review of pathogenic pathways.

Immunoregulatory effects of TPM203 peptide-nanoparticle therapy in pemphigus vulgaris.

Grinspan Syndrome Associated With Pemphigus Vulgaris Induced by COVID-19 Vaccination.

Indian journal of dermatology, venereology and leprology

Longitudinal trends in immunological biomarkers, and predictors of relapse in pemphigus treated with rituximab: A prospective cohort study.

Current opinion in immunology

B cell-targeted therapies in autoimmune skin disease: current advances and challenges.

Mitochondrial-dependent apoptosis and STAT3 activation induced by oxidative stress in pemphigus vulgaris.

Scientific reports

Through the Microscope Lens: Investigating the Mechanisms of Desmosome Disruption in Pemphigus.

Safety, tolerability, pharmacokinetics and pharmacodynamic effects of desmoglein 3 peptide-coupled tolerizing nanoparticles in pemphigus.

Dermatology practical & conceptual

Novel Serum Oxidative Stress Biomarkers in Pemphigus Vulgaris: Clinical Insights and Implications for Pathogenesis.

Dermatology practical & conceptual

Endoscopic Findings of Mucosal Pemphigus Vulgaris: Clinical Correlation and Diagnostic Value.

The effectiveness and safety of ofatumumab for the treatment of pemphigus vulgaris: a cohort study based on a registry database.

Anais brasileiros de dermatologia

Penile erosions: an atypical initial manifestation of pemphigus vulgaris.

Nail Involvement in Pemphigus: A Clinical and Dermoscopic Prospective Study.

Skin appendage disorders

Data-driven image analysis to determine antibody-induced dissociation of cell-cell adhesion and antibody pathogenicity in pemphigus.

PNAS nexus

Desmosomal cadherin tension loss in pemphigus vulgaris mediated by the inhibition of active RhoA at cell-cell adhesions.

iScience

A Single Centre Cross-Sectional Observational Study on Dermatoscopy of Oral Mucosal Disorders and Histopathological Correlation in Tertiary Care Centre from Central India.

Clinical, cosmetic and investigational dermatology

Dupilumab as Immunomodulatory Rescue for Severe Recalcitrant Pemphigus Vulgaris: A Case Report and Literature Review.

A Clinico-Epidemiological Study of Various Autoimmune Vesiculobullous Disorders in a Tertiary Care Center.

Rituximab-induced subcutaneous sarcoidosis in a patient with refractory pemphigus vulgaris.

Therapie

Brown patches and erosions with an erythematous base.

Indian dermatology online journal

Ultra-Low-Dose Rituximab in Pemphigus Vulgaris: How Low is the Lowest?

Indian dermatology online journal

Low Dose Vs Conventional Rituximab Regimen in Pemphigus Vulgaris - A Retrospective Single Centre Comparative Analysis to Assess the Clinical Efficacy and Cost-Effectiveness.

Indian dermatology online journal

Assessment of Efficacy of Adjuvant Topical Rituximab Encapsulated in Nanoparticle Gel in Oral Pemphigus Vulgaris: A Randomized, Double-Blind, Placebo-Controlled, Pilot Study.

A Case Report of Pemphigus Vulgaris Initially Misdiagnosed as Tinea Capitis: Infectious Consequences of Diagnostic Delay in a Patient Treated With Rituximab.

Pulmonary cryptococcosis in the setting of immunosuppression by methylprednisolone monotherapy for oral pemphigus: a case report and literature review.

Frontiers in medicine

Postepy dermatologii i alergologii

Evaluation of total sulfhydryl levels and dietary habits in pemphigus vulgaris.

International journal of molecular sciences

The Role of Microbiota in the Pathogenesis of Bullous Pemphigoid and Pemphigus Vulgaris: Evidence, Controversies, and Perspectives.

Correlation of Antimuscarinic Acetylcholine Receptor Antibody Titers With Pemphigus Disease Activity at Baseline and Following Phase I Pulse Therapy.

Acta stomatologica Croatica

A 10-Year Observational Study on Treatment Approaches in Pemphigus and Pemphigoid.

Role of Desmoglein Autoantibody in the Diagnosis of Pemphigus Vulgaris: A Case Report.

Acta medica Indonesiana

Journal of cancer research and therapeutics

Pemphigus vulgaris following radiotherapy in head and neck cancer: Clinicopathological perspective of a rare cutaneous manifestation after radiotherapy treatment.

The Journal of dermatological treatment

Treatment of pemphigus and other neglected skin conditions with PC111, a human anti-Fas Ligand monoclonal antibody: a potential disease modifier.

Unusual Presentation of Pemphigus Vulgaris as a Solitary Ulcerative Scalp Lesion: A Case Report.

Alterations in chemokine receptor-ligand interactions and costimulatory molecules in DC-NK crosstalk: A novel therapeutic approach for pemphigus vulgaris.

Immunology letters

Nonfatal Strongyloides Stercoralis Hyperinfection Secondary to Pemphigus Vulgaris Immunosuppressant Treatment: Case Report and Brief Literature Review.

Acta medica portuguesa

Rilzabrutinib-induced transition from pemphigus vulgaris to pemphigus foliaceous: a case report and literature review.

Dermatology reports

Pulmonary Inflammatory Myofibroblastic Tumor in a Patient Treated for Pemphigus Vulgaris: A Case Report.

Antibodies (Basel, Switzerland)

Circulating Antibodies Against DSG1 and DSG3 in Patients with Oral Lichen Planus: A Scoping Review.

Mediterranean journal of rheumatology

HLA DRB1* Allele Lupus Erythematosus, Rheumatoid Arthritis, and other Autoimmune Disorders with Skin Involvement.

The role of B cell-activating factor system in autoimmune diseases: mechanisms, disease implications, and therapeutic advances.

A Multimodal Approach to Diagnosis of Immunobullous Diseases: Integrating Clinical, Histopathological, and Immunofluorescence Findings.

Rare Ocular Association With Hailey-Hailey Disease.

Ochsner journal

Treatment of refractory pemphigus vulgaris with efgartigimod.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Pemphigus Vulgaris: A rare cause of esophageal bleeding and stricture.

The Efficacy of Dupilumab in Pemphigus Vulgaris.

JPMA. The Journal of the Pakistan Medical Association

Correlation and assessment of vitamin D deficiency with disease severity in patients suffering from pemphigus vulgaris.

Journal of palliative care

Pioneering Palliative Care in Pemphigus Vulgaris: A Landmark Case Report from Myanmar.

The Journal of allergy and clinical immunology

Antigen-specific immune responses and microbiota interactions in skin: Insights into autoimmune skin diseases and emerging therapeutic strategies.

The Multikinase Inhibitor Midostaurin Mitigates Loss of Intercellular Adhesion and Skin Blistering in Pemphigus Vulgaris.

The Journal of dermatology

Evaluating the Role of Low-Dose Methotrexate in Pemphigus Vulgaris: A Commentary on Recent Findings.

Factors associated with persistent anti-desmoglein positivity after remission in pemphigus vulgaris: a prospective registry-based cohort study.

Juvenile pemphigus vulgaris: A narrative review.

Medicine

Successful treatment of pemphigus vulgaris with obinutuzumab.

Dermatology practical & conceptual

Risk of Osteoporosis Associated with Glucocorticoid Use in Pemphigus Vulgaris: Insights from a Retrospective Cohort Study.

Advances in skin & wound care

Pemphigus Vulgaris: Clinical Aspects and Treatments.

JAK1/2 Inhibitors Alleviate the Damage of Intercellular Adhesion by Reducing Endoplasmic Reticulum Stress-Induced Apoptosis in Pemphigus Vulgaris.

Experimental dermatology

Journal of the American Academy of Dermatology

Efficacy, safety, and B-cell depletion capacity of 3 rituximab dosing regimens in the treatment of moderate-to-severe pemphigus vulgaris and pemphigus foliaceus: A 52-week clinical trial.

High-Sensitivity Cell-Based Plasmonic Biolayer Interferometry with a Two-Tiered Enhancement for Clinical Autoimmunity Surveillance of Pemphigus Vulgaris.

ACS nano

A red nodule in the umbilicus of an older man.

Skin health and disease

Diagnostics (Basel, Switzerland)

Mucoscopic Features of Oral Lichen Planus: A Retrospective Comparative Study with Inflammatory Mimickers.

Management of Oral Mucositis in Pediatric Patients: A Practical Overview of Available Treatment.

Pediatric dermatology

Indian journal of dermatology, venereology and leprology

Correlating pemphigus disease area index (PDAI) severity categories with oral disease severity score (ODSS) in oral mucosal pemphigus - A pilot study.

Pathology, research and practice

The application of direct immunofluorescence in the pathological diagnosis of oral mucosal diseases: Series of 116 cases.

Epac1 contributes to apremilast-mediated rescue of pemphigus autoantibody-induced loss of keratinocyte adhesion.

JCI insight

Elevated Fab glycosylation of autoantibodies maintained during B cell depletion therapy.

Scientific reports

Severe psoriasis vulgaris complicating pemphigus vulgaris: A case report.

Medicine

Revista medica del Instituto Mexicano del Seguro Social

[CAR-T cells in Dermatology: Mechanisms of action and applications in autoimmune diseases].

JAK-STAT pathway, type I/II cytokines, and new potential therapeutic strategy for autoimmune bullous diseases: update on pemphigus vulgaris and bullous pemphigoid.

Direct inhibition precedes p38 mitogen activated protein kinase-mediated uncoupling in desmosomes to reduce desmoglein 3 adhesion by pemphigus autoantibodies.

Endocrine, metabolic & immune disorders drug targets

The Liraglutide-Induced Pemphigus Vulgaris: A First Case Report Highlighting Autoimmune Risks of GLP-1 Receptor Agonists.

The American journal of tropical medicine and hygiene

Risk Factors Associated with Oral Candidiasis in Pemphigus Vulgaris Patients: Results from a Case-Control Study in India.

Genetic variations in the ST18 gene and their association with pemphigus vulgaris in Vietnamese patients: insights from a case series.

Dermatology reports

The American journal of the medical sciences

Association of pemphigus vulgaris with infections in end-stage renal disease patients.

Outcome measurement in pemphigus clinical research: a scoping review on heterogeneity in outcome reporting and definitions.

Archives of dermatological research

Cutaneous epidermal growth factor receptor expression (EGFR) and soluble EGFR levels are elevated in patients with pemphigus vulgaris: a longitudinal study.

Clinical outcomes and prognostic factors of pemphigus vulgaris and pemphigus foliaceus: A 20-year retrospective study.

Chinese medical journal

Journal of dental sciences

A retrospective analysis of oral autoimmune bullous diseases at a Thai oral medicine center.

JID innovations : skin science from molecules to population health

Integration of Longitudinal Clinical, Immunologic, and Environmental Data for Enhanced Disease Monitoring and Management in Pemphigus Vulgaris: A Case Study.

Interleukin (IL)-34 promotes the inflammatory role of IL-1β-producing myeloid cells in pemphigus lesions.

The Journal of the Association of Physicians of India

Rare Presentation of Rituximab-induced Interstitial Lung Disease in a Patient with Pemphigus Vulgaris.

Plasmapheresis for Facilitating Readministration of Rituximab After Paradoxical Exacerbation in Pemphigus Vulgaris: A Case Report.

Clinical case reports

International immunopharmacology

MicroRNAs in patients with pemphigus: A systematic review.

Trichoscopy of Pemphigus Vulgaris and Foliaceus on Black Scalp.

Skin appendage disorders

Rare Coexistence of Pemphigus Vulgaris and Eosinophilic Esophagitis: A Report of Two Cases.

Clinical case reports

Lipid Profile Scores Predict Severity of Pemphigus: A Cross-Sectional Study.

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