Raras
Buscar doenças, sintomas, genes...
Peste
ORPHA:707CID-10 · A20.0CID-11 · 1B93DOENÇA RARA

A peste é uma infecção bacteriana grave causada pela bactéria Yersinia pestis.

Mantido por Agente Raras·Colaborar como especialista →

Introdução

O que você precisa saber de cara

📋

A peste é uma infecção bacteriana grave causada pela bactéria Yersinia pestis.

Pesquisas ativas
3 ensaios
26 total registrados no ClinicalTrials.gov
Publicações científicas
11.167 artigos
Último publicado: 2026 Apr 8

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
Unknown
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
0.0
Worldwide
Casos conhecidos
2
pacientes catalogados
Início
All ages
🏥
SUS: Sem cobertura SUSScore: 0%
CID-10: A20.0
Você se identifica com essa condição?
O Raras está aqui pra te apoiar — com ou sem diagnóstico

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Entender a doença

Do básico ao detalhe, leia no seu ritmo

Preparando trilha educativa...

Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🫃
Digestivo
7 sintomas
🧬
Pele e cabelo
5 sintomas
❤️
Coração
3 sintomas
🩸
Sangue
3 sintomas
👁️
Olhos
2 sintomas
🫁
Pulmão
2 sintomas

+ 27 sintomas em outras categorias

Características mais comuns

90%prev.
Fadiga
Muito frequente (99-80%)
90%prev.
Linfadenite
Muito frequente (99-80%)
90%prev.
Febre
Muito frequente (99-80%)
55%prev.
Esplenomegalia
Frequente (79-30%)
55%prev.
Taquicardia
Frequente (79-30%)
55%prev.
Hepatomegalia
Frequente (79-30%)
55sintomas
Muito frequente (3)
Frequente (17)
Ocasional (29)
Muito raro (6)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 55 características clínicas mais associadas, ordenadas por frequência.

FadigaFatigue
Muito frequente (99-80%)90%
LinfadeniteLymphadenitis
Muito frequente (99-80%)90%
FebreFever
Muito frequente (99-80%)90%
EsplenomegaliaSplenomegaly
Frequente (79-30%)55%
TaquicardiaTachycardia
Frequente (79-30%)55%

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico11.167PubMed
Últimos 10 anos200publicações
Pico2025131 papers
Linha do tempo
2026Hoje · 2026🧪 2003Primeiro ensaio clínico📈 2025Ano de pico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
3Fase 32
2Fase 26
1Fase 14
·Pré-clínico2
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 14 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Peste

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

🟢 Recrutando agora

2 pesquisas recrutando participantes. Converse com seu médico sobre a possibilidade de participar.

Outros ensaios clínicos

26 ensaios clínicos encontrados, 3 ativos.

Distribuição por fase
Ver todos no ClinicalTrials.gov
🧪 Está conduzindo uma pesquisa?
Divulgue para pacientes e familiares que acompanham esta doença.
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Publicações mais relevantes

Timeline de publicações
3.167 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 3.167

#1

ERAD inhibitor Eeyarestatin I (EerI) suppresses duck plague virus by restoring STING-mediated antiviral immunity.

Poultry science2026 Mar 17

Este estudo identificou Eeyarestatin I (EerI) como um promissor candidato a medicamento antiviral contra o vírus da peste dos patos (DPV), uma doença altamente contagiosa em aves. O EerI demonstrou suprimir a replicação viral em células *in vitro* ao restaurar a imunidade antiviral mediada por STING, que o vírus DPV tenta desativar. Esta descoberta oferece uma nova abordagem terapêutica potencial para combater a peste dos patos, onde as vacinas atuais não oferecem proteção completa, embora mais pesquisas sejam necessárias para sua aplicação clínica.

🇧🇷 traduzido
#2

Downregulation of the host ribonucleotide reductase subunit M2 via the Wnt/β-catenin pathway is a novel mechanism for duck plague virus replication and a potential antiviral target.

Poultry science2026 Mar 05

O vírus da peste do pato (DPV), uma ameaça significativa para a indústria de aves aquáticas, promove sua replicação ao degradar uma enzima hospedeira essencial para a síntese de DNA, a RRM2. Isso ocorre através da ativação da via de sinalização Wnt/β-catenina, que leva à degradação da RRM2 – uma enzima que normalmente restringe a replicação viral. Essa compreensão aprofunda o conhecimento da patogênese do DPV e identifica o eixo Wnt/β-catenina-RRM2 como um alvo promissor para o desenvolvimento de novas intervenções antivirais para proteger as aves.

🇧🇷 traduzido
#3

Integrating microclimate to understand vector development and disease patterns: challenges and lessons from plague in Madagascar's Central Highlands.

Proceedings. Biological sciences2026 Mar 18

A peste em Madagascar é uma doença grave com padrões sazonais, cuja transmissão por pulgas vetoras é influenciada por um complexo sistema ecológico e climático. Este estudo investigou como o microclima afeta o desenvolvimento das pulgas e, embora tenha observado inicialmente uma possível ligação com os casos de peste, essa associação direta não se confirmou completamente após validações. Isso indica que a relação entre o clima, os vetores e a ocorrência de surtos é mais complexa do que o previsto e exige mais pesquisas, especialmente sobre o microclima nos abrigos dos vetores, para que pacientes e médicos possam ter melhores ferramentas de previsão e controle da doença.

🇧🇷 traduzido
#4

A prospective cohort study to describe the morphology of buboes in patients with bubonic plague using ultrasound imaging.

PLoS neglected tropical diseases2026 Mar

Este estudo inovador, usando ultrassom em pacientes com peste bubônica, revelou que o tamanho e a morfologia dos bubões (gânglios linfáticos inchados) geralmente não se alteram significativamente ao longo do tempo, mesmo com a melhora clínica do paciente. Isso indica que, para médicos e pacientes, a aparência do bubão não é um bom indicador da eficácia do tratamento ou da recuperação, e que instrumentos como paquímetros digitais são imprecisos para sua medição.

🇧🇷 traduzido
#5

POU2F1 Promotes Chemoresistance in Colorectal Cancer Cells via Attenuates the MDR2 Degradation Mediated by PPP1R11 Lactylation.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)2026 Mar 07

Este estudo identifica a proteína POU2F1 como um fator chave na resistência à quimioterapia em células de câncer colorretal. Quando super expressa, POU2F1 diminui a degradação da proteína MDR2, que é responsável por expelir os medicamentos quimioterápicos, tornando os tratamentos menos eficazes. Compreender como POU2F1 regula essa resistência através de um processo chamado lactilação pode abrir caminho para o desenvolvimento de novas estratégias que restaurem a sensibilidade dos tumores à quimioterapia, melhorando as chances de sucesso do tratamento.

🇧🇷 traduzido

Publicações recentes

Ver todas no PubMed

📚 EuropePMC7.167 artigos no totalmostrando 199

2026

Molecular Investigation of Borrelia spp. in Small Ruminants and Collected Hard Ticks from Them in Kurdistan Province, Western Iran.

Vector borne and zoonotic diseases (Larchmont, N.Y.)
2026

Development and evaluation of an assay for the detection of tick-borne encephalitis virus RNA via real-time PCR with reverse transcription.

Parasites &amp; vectors
2026

ERAD inhibitor Eeyarestatin I (EerI) suppresses duck plague virus by restoring STING-mediated antiviral immunity.

Poultry science
2026

Molecular identification and phylogenetic analysis of marmots in the Xinjiang's Altai Mountains, a newly discovered plague focus of China.

Biochemistry and biophysics reports
2026

Downregulation of the host ribonucleotide reductase subunit M2 via the Wnt/β-catenin pathway is a novel mechanism for duck plague virus replication and a potential antiviral target.

Poultry science
2026

Integrating microclimate to understand vector development and disease patterns: challenges and lessons from plague in Madagascar's Central Highlands.

Proceedings. Biological sciences
2026

A prospective cohort study to describe the morphology of buboes in patients with bubonic plague using ultrasound imaging.

PLoS neglected tropical diseases
2026

An Epidemiological Study among Substance Abusers Visiting the Outpatient Opioid Assisted Treatment (OOAT) Centre Clinics in District Patiala.

Indian journal of community medicine : official publication of Indian Association of Preventive &amp; Social Medicine
2026

Microfluidic electroporation for drug and gene delivery: Driving innovation from single-cell precision to high-throughput preclinical and therapeutic platforms.

Advanced drug delivery reviews
2026

Emergence, global dispersal, and local adaptations of Yersinia pestis, the agent of plague.

Applied and environmental microbiology
2026

The Professional Plague of Incivility: A Christian Nursing Response.

Journal of Christian nursing : a quarterly publication of Nurses Christian Fellowship
2026

Comparative Genomics and Metabolomics of Domesticated, Pladienolide-Producing Streptomyces Bacteria.

Journal of natural products
2026

A Simplified Protocol for Protecting Palatal Soft Tissue Donor Sites Using an Oral Mucoadhesive Bandage.

Journal of visualized experiments : JoVE
2025

The WHO Guidance on Clinical Ethics: Some concerns from the Indian context.

Indian journal of medical ethics
2026

Application of Long-Read Sequencing for Genotyping, Epigenetic Profiling and Surveillance of Yersinia pestis Isolates from Natural Foci and Disease Outbreaks in Central Asia.

Vector borne and zoonotic diseases (Larchmont, N.Y.)
2026

POU2F1 Promotes Chemoresistance in Colorectal Cancer Cells via Attenuates the MDR2 Degradation Mediated by PPP1R11 Lactylation.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
2026

Study on the differentiated impact of climate change on plague epidemics in Northern and Southern China, 1912-1949.

PLoS neglected tropical diseases
2026

Spatial characteristics and driving factors of human brucellosis and plague infections in the Meriones unguiculatus plague focus in China.

One health (Amsterdam, Netherlands)
2026

Rapid and sensitive detection of feline herpesvirus-1 using fluorescent microspheres as labels for immunochromatographic test strips.

Veterinary research communications
2026

Plasma albumin contributes to early Yersinia pestis survival at the onset of flea infection.

PLoS pathogens
2026

The Evolution of Modeling Approaches: From Statistical Models to Deep Learning for Locust and Grasshopper Forecasting.

Insects
2026

A RPA-CRISPR/Cas12a-Powered Catalytic Hairpin Assembly Fluorescence Biosensor for Duck Plague Virus Virulent Strain Detection.

Biosensors
2026

An Adenoviral Vectored Vaccine Protects Mice Against Aerosol Challenge with Yersinia pestis.

Molecular therapy : the journal of the American Society of Gene Therapy
2026

[Attenuation of Yersinia pestis virulence by gene depletion at the end of each historical plague pandemic].

Medecine sciences : M/S
2026

Pulmonary delivery of a humanized heavy-chain antibody LcrV-X19-R1 confers complete protection against fatal pneumonic plague in mice.

International journal of biological macromolecules
2025

Convergent gut microbiome adaptation and pervasive antibiotic resistome in Qinghai-Tibet Plateau passerines.

Frontiers in microbiology
2026

Xenopsylla buxtoni fleas as a dominant species harboring multiple infections of Wolbachia lineages in the ancient plague epicenters of Iran.

PLoS neglected tropical diseases
2026

Psychosocial impacts of a mouse plague and ongoing psychological stress.

Scientific reports
2026

Magnetic nanozyme-based dual-mode biosensor for highly sensitive detection of Yersinia pestis gene via hybridization chain reaction amplification.

Mikrochimica acta
2026

Climate change impacts on the global potential distribution of the human flea, Pulex irritans, and the global health risks.

Scientific reports
2026

What's in a name? Metabolite identification: challenges and pitfalls in untargeted metabolomics.

Metabolomics : Official journal of the Metabolomic Society
2026

Cloning, expression, purification and serodiagnosis evaluation of three Francisella tularensis proteins.

Diagnostic microbiology and infectious disease
2026

Updates on niosomes in interfering nucleic acid delivery for cancer treatment: A comprehensive review and future perspectives.

Medical oncology (Northwood, London, England)
2026

High Temperature Ni-Diffusion Plaguing Ionic Conductivity of Solid Oxide Cell.

Small (Weinheim an der Bergstrasse, Germany)
2026

Molecular detection of Coxiella burnetii in vaginal and rectal swab samples of small ruminants from Kermanshah Province, western Iran.

BMC veterinary research
2026

Brefeldin A inhibits duck plague virus replication by impairing virion envelopment.

Poultry science
2025

Virulence Reduction in Yersinia pestis by Combining Delayed Attenuation with Plasmid Curing.

Biomolecules
2025

High Mortality in the Male Breast Cancer Community: A Report on Its Drivers and a Demand for Change in Healthcare Policy.

Cureus
2026

A rapid on-site diagnostic method for goose parvovirus disease based on recombinase polymerase amplification and CRISPR/AsCas12a.

International journal of biological macromolecules
2026

Inhalable DNA nano-adjuvant elicits robust lung-resident memory immunity against pneumonic plague.

Biomaterials
2026

Barriers to accessing high-quality cancer medicines in Cameroon. A qualitative study of the views and practices of regulators and frontline healthcare providers.

PLOS global public health
2026

B-cell epitope prediction in the age of machine learning: advancements and challenges.

Journal of translational medicine
2025

Imperial Careering: India and the Women's Medical Movement, 1896-1920.

Social history of medicine : the journal of the Society for the Social History of Medicine
2025

Preventing Epidemics at the Borders: The Public Health Policy of the Greek State (1821-1909).

Social history of medicine : the journal of the Society for the Social History of Medicine
2026

Who the Plague Chose: Exploring Intersecting Social Risk in Black Death Mortality.

American journal of biological anthropology
2026

Structural and Biophysical Characterization of the Yersinia Type Three Secretion System ATPase YscN.

Proteins
2025

Combating the Plague of Health Misinformation in Memes: Exploring the Influence of Transmission and Ritual Vaccine Messaging Using the Six-Segment Message Strategy Wheel.

Journal of health communication
2026

Identifying the potential anti-lung cancer targets of Baicalein using a network pharmacology approach.

Scientific reports
2026

Commentary on Seersholm Et al.: Yersinia pestis Infection Is Not Synonymous With Deadly Plague in Neolithic Scandinavia.

American journal of biological anthropology
2026

Composite B-spline regularized delta functions for the immersed boundary method: Divergence-free interpolation and gradient-preserving force spreading.

Journal of computational physics
2026

Study on the Effect and Mechanism of Lomatogonium rotatum (L.) Fries ex Nym Extract on NAFLD Through Metabolomics.

Biomedical chromatography : BMC
2026

Intranasal unadjuvanted LcrV boosts parental Yersinia OMV primed lung immunity against pneumonic plague in mice.

Nature communications
2025

Genomic Diversity of Toxigenic Strains of Vibrio cholerae O1 Biovar El Tor Isolated During Three Waves of the 7th Cholera Pandemic.

Doklady. Biochemistry and biophysics
2026

Pulex irritans: Historic repellents, insecticides, and flea traps from the 16th to the 19th century.

Clinics in dermatology
2026

Short-time thermal inactivation of surrogates of the public transport microbiome with a low-cost thermoresistometer.

Scientific reports
2025

Unmasking the dilemma: Public health, safety, and the challenges of anonymity in emergency management and homeland security.

Journal of emergency management (Weston, Mass.)
2026

What the landscape can tell: An integrative stratigraphic prospection approach to localize a Black Death mass grave in Erfurt/Central Germany.

PloS one
2025

A Study of the Microdynamics of Early-Childhood Learning.

The journal of political economy
2025

Systematic analysis of spontaneous tandem genome amplification events in Yersinia pestis.

PloS one
2025

Enhanced YOLOv8n-Based Three-Module Lightweight Helmet Detection System.

Sensors (Basel, Switzerland)
2025

Molecular Tracing and Comparative Genomics Analysis of Yersinia pestis Strains Isolated from Wild Rodents in Yunnan Province in 2022.

Pathogens (Basel, Switzerland)
2025

A Novel, Broad-Spectrum, Virulent Bacteriophage Targeting Yersinia pestis Isolated from the Soil of Wild Rodent Nests in Yunnan Province, China.

Pathogens (Basel, Switzerland)
2025

Environmental changes and risk of plague epidemics in Indonesia.

PLoS neglected tropical diseases
2026

Characterizing a newly identified avian herpesvirus-specific gene SORF3 in DPV and its roles in potential pathogenicity.

Journal of virology
2026

Exploring the Role of Long Noncoding RNAs in Breast Cancer Progression: A Comprehensive Study on Biomarkers and Therapeutic Approaches.

Cancer medicine
2026

A targeted mutation in ICP8 attenuates duck plague virus by disrupting replication and proposes a vaccine strategy.

Poultry science
2026

The views of Danylo Samoylovich (1744-1805) on the prevention, course and treatment of the plague.

Studies in history and philosophy of science
2026

Yersinia pestis plasminogen activator protease is regulated by the PhoP/PhoQ two-component system.

Journal of bacteriology
2025

Transforming One Health in India: National Multisectoral Mixed Method Study on Prioritization of Zoonotic Diseases.

JMIR public health and surveillance
2025

Farmers' preferences for Peste des petits ruminants disease vaccine delivery attributes in Uganda.

Frontiers in veterinary science
2025

Next-generation vaccines against bacterial pathogens: mRNA and beyond.

Frontiers in immunology
2025

Yersinia pestis transmission risk associated with Himalayan marmots (Marmota himalayana) of the Qinghai-Tibet plateau.

One health (Amsterdam, Netherlands)
2025

Impact of virulence factors overexpression on Listeria monocytogenes F2365 epidemic strain fitness and the limitations of surrogate species in UHT and raw milk.

NPJ science of food
2026

SUPER: Upcycling Genetic Parts for Precise Gene Expression Control, Leakage Minimization, and Genetic Circuit Stability.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
2026

Opening Pandora's box: First insights into the genetic diversity of Aphanomyces astaci in Switzerland.

Journal of invertebrate pathology
2026

Dynamic interfacial anchoring in core-shell MoS2-coated Sn anodes enables ultrastable lithium storage.

Journal of colloid and interface science
2026

Performance of diagnostic procedures for bubonic plague in endemic settings in Madagascar: a prospective test accuracy sub-study within the IMASOY trial.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
2025

Infectome analysis of small mammals in Southern China reveals pathogen ecology and emerging risks.

Nature communications
2026

Regulatory role for tumor suppressor REST on estrogen receptor (ESR1) expression and leiomyoma pathophysiology.

The Journal of biological chemistry
2025

Knowledge, attitude and practices among Healthcare Workers towards Pulmonary Plague Infection following an outbreak in Madagascar, 2017: A pilot study.

PloS one
2025

Influence of human intervention on rodent population dynamics in Southwest China.

One health (Amsterdam, Netherlands)
2026

Differential sampling for genetic analyses of Treponema pallidum and for radiocarbon dating in archaeological bone.

International journal of paleopathology
2025

Robust DNN-based Decoder Model with an Embedded State-Space Model Layer.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
2026

Integrating Ensemble NSGA-II for Multi-Objective Process Optimization: Refolding of Proinsulin as a Case Study.

Biotechnology and bioengineering
2026

Informing a Program to Increase Lifejacket Use with Pacific Northwest Fishermen.

Journal of agromedicine
2025

Development of Montanide-based inactivated vaccine against duck plague virus in Bangladesh.

Journal of advanced veterinary and animal research
2025

Species Composition, Diversity, Abundance, and Phylogeny of Fleas of Small Mammals in Selected Plague-Endemic and Nonendemic Areas of Tanzania.

Journal of parasitology research
2025

Bacteriological research and 'puerperal' fever: female health and childbirth in late colonial India.

Medical history
2026

Methanol extract of Artemisia argyi against influenza a virus via inhibition of PI3K-AKT pathway activation.

Journal of ethnopharmacology
2026

Development of a rapid and sensitive one-pot recombinase polymerase amplification assay for the simultaneous detection of Bacillus anthracis and Yersinia pestis with naked eye result read-out.

International journal of biological macromolecules
2025

Seasonality affects key physiological pathways in Pontastacus leptodactylus during an Aphanomyces astaci epidemic outbreak.

Scientific reports
2025

Interaction of Bacteria and Fleas, Focusing on the Plague Bacterium-A Review.

Microorganisms
2025

Evaluating the early diversification of Yersinia pestis and its phylogeographic expansion over 96 years of evolution in Madagascar.

Communications biology
2025

New fluorescently labeled isothiocyanate derivatives as a potential cancer theranostic tool.

Scientific reports
2025

Spread of the plague in Venice, 1630-1631: epidemic entropy in a "natural experiment".

medRxiv : the preprint server for health sciences
2025

Development of a cost-effective LAMP method for screening and monitoring enteropathogenic Yersinia in environmental matrices.

Science in One Health
2025

Tikhon Efimovich Boldyrev (1900-1984): A Soviet epidemiologist's contributions to public health in 1950s China.

Journal of medical biography
2025

Spatial and temporal characterisation of genetic and phenotypic properties of Yersinia pestis in Kazakhstan's natural plague foci.

Environmental analysis, health and toxicology
2025

Fulminant Yersinia Pestis Infection in a Known HIV-Positive Patient: A Case Report of Identification in Nigeria 2024.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
2025

Metagenomics research on the gut microbiota of the Marmota himalayana of the Sanjiangyuan National Nature Reserve in Qinghai Province, China.

Biosafety and health
2025

Improved interpretability in LFADS models using a learned, context-dependent per-trial bias.

bioRxiv : the preprint server for biology
2025

Evidence of populational Burkholderia pseudomallei exposure in Madagascar.

PLoS neglected tropical diseases
2025

The Plague Doctor's Parody: Ridiculing François Chicoyneau during the Great Plague of Marseille, 1720-1722.

Journal of the history of medicine and allied sciences
2025

First assessment of plague in terrestrial small mammals and fleas from Makira Natural Park and surroundings, North-eastern Madagascar.

PLoS neglected tropical diseases
2025

Polydopamine coating for anchoring icariin-regulated CF/PEEK with enhanced cytocompatibility and osteogenic activity.

Journal of materials chemistry. B
2025

Mitogenomic architecture and phylogenetic placement of Ctenophthalmus yunnanus and Frontopsylla diqingensis: insights from comparative genomics.

Frontiers in veterinary science
2025

Mereological Anti-Conservatism.

Acta analytica : philosophy and psychology
2026

Elucidation of Proteoforms of Chinese Hamster Ovary (CHO) Phospholipase B-Like 2 (PLBL2) Captured From a Monoclonal Antibody.

Biotechnology and bioengineering
2025

Revolutionizing patient recruitment experience in trials using the design-thinking framework.

Perspectives in clinical research
2026

The Neuropsychiatric Disturbances of Delirium: A Review of Syndromes and Their Treatment.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
2025

A Proteomic View on Persistence of Yersinia pestis in Tap Water Microcosm.

Current microbiology
2025

Restriction of the main lineages of Mycobacterium africanum to West Africa: Insights from host-pathogen interaction studies.

Tuberculosis (Edinburgh, Scotland)
2026

Crayfish plague and microsporidiosis occurrence in wild populations of the white-clawed crayfish Austropotamobius pallipes complex in Trentino (North-East Italy).

Journal of invertebrate pathology
2025

DPV UL46 activates EGFR-PI3K-AKT pathway to antagonize innate immunity by interfering with cGAS-STING-TBK-IRF7 Signalsome formation.

International journal of biological macromolecules
2025

Plagued by the Past, Pressed by the Present: A One Health Perspective on Yersinia pestis.

Biomedicines
2025

Duck Plague Virus Full-Length UL15 Protein Is a Multifunctional Enzyme Which Not Only Possesses Nuclease Activity but Also Exerts ATPase and DNA-Binding Activity.

Veterinary sciences
2025

[The results of the detection of specific IgG antibodies to Ebola virus (Filoviridae: Orthoebolavirus) in residents of the Republic of Guinea after the end of the epidemic].

Voprosy virusologii
2026

Comparative study of Bayesian and frequentist methods for epidemic forecasting: Insights from simulated and historical data.

Statistical methods in medical research
2025

The long and intimate association between humans and parasites through time.

Parasitology
2025

[Insights from plague control from a "One Health" perspective: Wu Lien-teh and the centennial legacy of public health in China].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]
2025

Genotyping of Coxiella burnetii isolates in Iran using Multiple-locus variable-number tandem repeat analysis (MLVA).

BMC microbiology
2025

Morphological variations of the femoral head-neck junction in historical skeletal material.

PeerJ
2025

BayesianFitForecast: a user-friendly R toolbox for parameter estimation and forecasting with ordinary differential equations.

BMC medical informatics and decision making
2025

Decolonizing pain and health-related research to advance research and optimize health.

Pain
2025

An update on osteoporosis management and fracture prevention strategies.

JAAPA : official journal of the American Academy of Physician Assistants
2025

An Historical and Epidemiological Analysis of Pontifical Mortality: Patterns, Causes and Narratives across the Centuries.

Journal of religion and health
2025

Febrile encephalopathy following a tick bite: A case report of Rickettsia conorii infection from Northeast Iran.

New microbes and new infections
2025

Pioneering discovery: US3-phosphorylated sites on VP22 orchestrate duck plague virus release and pathogenicity.

Poultry science
2025

Strategic drive toward bi-linker MOFs: an efficient electrocatalyst for hydrogen and oxygen evolution reactions.

RSC advances
2025

BF2-Postmodified Cobalt-Porphyrin Covalent Organic Framework for High-Performance Specific Detection of NH3.

ACS sensors
2025

[EXPERIENCE IN ELIMINATING PLAGUE OUTBREAKS IN JAPAN AND RUSSIA IN THE EARLY XX CENTURY].

Problemy sotsial'noi gigieny, zdravookhraneniia i istorii meditsiny
2025

Evidence of Coxiella burnetii infection among pregnant and aborted women: A systematic review and meta-analysis.

New microbes and new infections
2025

Epidemics on glass paintings.

Clinics in dermatology
2025

Ni-Zn Dual-Atom Sites Enable Synergistic Parallel Pathways for Efficient Photosynthesis of H2O2 with Long-Term Stability.

Journal of the American Chemical Society
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A South African Scenario: Structure and Function of Peptides of the Adipokinetic Hormone Family of the Brown Locust, Locustana pardalina, and the Putative Role of These Peptides in Plague Management.

Archives of insect biochemistry and physiology
2025

Comparative genomic analysis of duck plague virus reveals evolutionary divergence between vaccine and contemporary field isolates in Thailand.

Poultry science
2025

More continuity than change following the Black Death epidemic in medieval Cambridge.

Scientific reports
2025

Silent Carriers: The Role of Rodents in the Emergence of Zoonotic Bacterial Threats.

Pathogens (Basel, Switzerland)
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Rodent-Borne Parasites and Human Disease: A Growing Public Health Concern.

Animals : an open access journal from MDPI
2025

Differentiation smelling footprints of the Chagas disease vector using an electronic nose based on artificial intelligence algorithms.

Anais da Academia Brasileira de Ciencias
2025

The UL24 gene affects duck plague virus replication, and its deletion attenuates virulence, enabling use as a vaccine.

Poultry science
2025

Lipid A mimetic BECC438 potentiates durable and balanced antibody responses in an ovalbumin murine model of vaccination.

ImmunoHorizons
2025

[Wu Lien-Teh and reports of the Second Plague in the Northeast in YuanDong Bao and Bingjiang ShiBao].

Zhonghua yi shi za zhi (Beijing, China : 1980)
2025

Translating Biomarker Discovery: From Bench to Bedside in Dry Eye Disease.

International journal of molecular sciences
2025

Whole genome sequencing of Yersinia pestis isolates from Central Asian natural plague foci revealed the role of adaptation to different hosts and environmental conditions in shaping specific genotypes.

PLoS neglected tropical diseases
2025

Effective treatment of advanced Oropouche virus, Rift Valley fever virus, and Dabie bandavirus infections with 4'-fluorouridine.

mBio
2025

Duck plague virus UL13 hijacks an RNA-binding protein, interferon induced protein with tetratricopeptide repeats 5, to promote replication.

International journal of biological macromolecules
2025

Discovery of Novel Hydroxyproline-Containing Microcystins in Western Lake Erie Cyanobacterial Bloom Samples.

ACS ES&amp;T water
2025

Development of duplex crystal digital PCR (dPCR) assay for detection and differentiation of NDRV and MDRV.

Veterinary and animal science
2025

Harnessing community-based one health interventions implementation beyond Mpox outbreak management in Africa: insights and benefits.

Infectious diseases of poverty
2025

DPV UL38 stabilizes MFN2 to subvert MAVS-mediated antiviral immunity in ducks.

Veterinary microbiology
2025

TNF signaling maintains local restriction of bacterial founder populations in intestinal and systemic sites during oral Yersinia infection.

mBio
2025

Duck plague virus ICP27 protein suppresses IFN-β production by dual targeting of DNA- and RNA-sensing pathways.

Veterinary microbiology
2025

The duck plague virus UL7 protein mediates RIG-I degradation to block host antiviral responses and promote viral pathogenesis.

Poultry science
2025

Alternatives to antibiotics for sustainable livestock production in the context of the One Health approach: tackling a common foe.

Frontiers in veterinary science
2025

Diagnosing plague in 17th century camelids from Romania along historical Silk Routes.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
2025

Reducing the threats of rodent-borne zoonoses requires an understanding and leveraging of three key pillars: disease ecology, synanthropy, and rodentation.

The Lancet. Planetary health
2025

Genetic Evidence of Yersinia pestis from the First Pandemic.

Genes
2025

Establishing a laboratory colony of the human flea, Pulex irritans: methods for collecting, rearing, and feeding.

Parasites &amp; vectors
2025

Ancient Origins and Global Diversity of Plague: Genomic Evidence for Deep Eurasian Reservoirs and Recurrent Emergence.

Pathogens (Basel, Switzerland)
2025

Effects of Diethylstilbestrol on Uterus Structure and Immunological Function in Mice During Early Pregnancy.

Toxics
2026

Chronic Aphanomyces astaci infection in wild white-clawed crayfish: risks and implications for breeding programs.

Journal of invertebrate pathology
2025

Deciphering pUL10's mastery in duck plague virus virulence: dual coordination of host immunity and viral replication.

Poultry science
2025

Notified Vector-Borne Diseases - China, 2005-2024.

China CDC weekly
2025

Prevalence of Acute Q Fever Among High-Risk Patients With Fever and Pneumonia Symptoms in Western Iran.

Journal of tropical medicine
2025

Characterisation of the noble crayfish immune response to oomycete-derived immunostimulants.

Fish &amp; shellfish immunology
2025

Periplasmic Binding Protein YiuA Enables Yersinia pestis to Scavenge Fe(III)-Catechol Siderophores.

ACS infectious diseases
2025

Pathogenic mechanisms and molecular features of a novel UL2 gene-deficient duck enteritis virus endemic to China.

Virulence
2025

The Voxelwise Encoding Model framework: A tutorial introduction to fitting encoding models to fMRI data.

Imaging neuroscience (Cambridge, Mass.)
2025

Tailoring light to create invariant modal spectra through complex channels.

Optics express
2025

Bronze Age Yersinia pestis genome from sheep sheds light on hosts and evolution of a prehistoric plague lineage.

Cell
2025

Meta-transcriptomics characterization of individual Marmota sibirica reveals a wide spectrum of viral and bacterial pathogens in Inner Mongolia of China.

Microbiology spectrum
2025

Yersinia pestis BipA is a novel regulator of pesticin and a type 6 secretion system.

Infection and immunity
2025

Coxiella burnetii: Emerging threats, molecular insights, and advances in diagnosis and control measures.

Journal of microbiological methods
2025

Yersinia Is Not Just the Plague: A Case Report of Yersiniosis Caused by Yersinia enterocolitica.

Cureus
2025

Incidence, molecular characterisation and epidemiology of Oriental rat flea, Xenopsylla cheopis (Rothschild, 1903) in synanthropic rodent hosts.

Journal of vector borne diseases
2025

Ciprofloxacin versus Aminoglycoside-Ciprofloxacin for Bubonic Plague.

The New England journal of medicine
2026

Analysis of the Effects of Hydrometeorological Conditions on Flea Indices of Two Rodent Species in Inner Mongolia.

Integrative zoology
2025

Influence of natural and anthropogenic drivers on plague risk in Southwest China: A multicenter cross-sectional study.

One health (Amsterdam, Netherlands)
2025

Insights into Yersinia pestis evolution through rearrangement analysis of 242 complete genomes.

Nature genetics
2025

Anticholinergic Burden in Serious Mental Illness: Is This a Plague Hiding in Plain Sight?

The American journal of psychiatry
2025

Our Future Health: consent, clinical risk, and industry issues plague the UK's biggest ever health research programme.

BMJ (Clinical research ed.)
2025

The quantification of surgical flow disruptions secondary to fogging and biofouling of endoscopic lens during endoscopic skull base surgeries.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
2025

Antibiotic Susceptibility Screening and Search for Resistance Genes in Yersinia pestis Clinical Isolates from Plague Outbreaks in Natural Foci of Kazakhstan (1926-2003).

Microbial drug resistance (Larchmont, N.Y.)
2025

Selective mortality during famine and plague events in medieval London.

Scientific reports
2025

Total Synthesis of Feglymycin Using Umpolung Amide Synthesis.

Angewandte Chemie (International ed. in English)
2025

Molecular profiling of the Australian plague locust pathobiome reveals a microbial driver of population suppression.

Journal of invertebrate pathology
2025

Potential Compounds as Inhibitors of Staphylococcal Virulence Factors Involved in the Development of Thrombosis.

Toxins
2025

Development and evaluation of a triplex real-time PCR assay for enhanced plague diagnostics in Madagascar.

PLoS neglected tropical diseases
2025

An ELISA-like sensitive and visual detection system targeting Yersinia pestis based on CRISPR/Cas12a and DNAzyme.

Journal of clinical microbiology
2025

Quantification of Small Molecule Partitioning in a Biomolecular Condensate with 2D Nuclear Magnetic Resonance Spectroscopy.

Chembiochem : a European journal of chemical biology
2025

Discovery of Yersinia LcrV as a novel biased agonist of formyl peptide receptor 1 to bi-directionally modulate intracellular kinases in triple-negative breast cancer.

Acta pharmaceutica Sinica. B
2025

Overcoming a false-positive mechanism in RapidFire MRM-based high throughput screening.

SLAS discovery : advancing life sciences R &amp; D
2025

A Heavy Issue: Changes in Body Size in London Before, During and After the Black Death.

American journal of biological anthropology
2025

Infectious disease outbreaks drive political mistrust.

Proceedings of the National Academy of Sciences of the United States of America
2025

Notes from the Field: Early-Season Human Plague Transmitted from an Infected Cat - Oregon, January 2024.

MMWR. Morbidity and mortality weekly report
2025

Cervicovagopathy: ligamentous cervical instability and dysstructure as a potential etiology for vagus nerve dysfunction in the cause of human symptoms and diseases.

Frontiers in neurology
2025

[The prevention and treatment of epidemic diseases in Weisheng Bao].

Zhonghua yi shi za zhi (Beijing, China : 1980)
2025

The Plague of Provence (1720-2) and debates in Britain on the cross-species transmission of disease.

Medical history
Ver todos os 7.167 no EuropePMC

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Doenças relacionadas

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. ERAD inhibitor Eeyarestatin I (EerI) suppresses duck plague virus by restoring STING-mediated antiviral immunity.
    Poultry science· 2026· PMID 41865653mais citado
  2. Downregulation of the host ribonucleotide reductase subunit M2 via the Wnt/&#x3b2;-catenin pathway is a novel mechanism for duck plague virus replication and a potential antiviral target.
    Poultry science· 2026· PMID 41850058mais citado
  3. Integrating microclimate to understand vector development and disease patterns: challenges and lessons from plague in Madagascar's Central Highlands.
    Proceedings. Biological sciences· 2026· PMID 41849189mais citado
  4. A prospective cohort study to describe the morphology of buboes in patients with bubonic plague using ultrasound imaging.
    PLoS neglected tropical diseases· 2026· PMID 41838707mais citado
  5. POU2F1 Promotes Chemoresistance in Colorectal Cancer Cells via Attenuates the MDR2 Degradation Mediated by PPP1R11 Lactylation.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany)· 2026· PMID 41793212mais citado
  6. Temporal shifts in polygenic traits track major epidemics in Western Eurasia.
    bioRxiv· 2026· PMID 41993326recente
  7. An evolutionary perspective on the nucleocytoplasmic shuttling mechanism of duck plague virus UL54 protein.
    Yi Chuan· 2026· PMID 41992888recente
  8. Graves reveal plague's inequitable toll.
    Nature· 2026· PMID 41992018recente
  9. The plague of 1720 and migration in Martigues (France) in the 17th and 18th centuries.
    PLoS One· 2026· PMID 41990020recente
  10. Ecologic Investigative Strategies to Determine Human Plague Exposure Sites, United States, 1991-2018.
    Emerg Infect Dis· 2026· PMID 41986255recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:707(Orphanet)
  2. MONDO:0019095(MONDO)
  3. GARD:18702(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Artigo Wikipedia(Wikipedia)
  6. Q133780(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Peste
Compêndio · Raras BR

Peste

ORPHA:707 · MONDO:0019095
Prevalência
Unknown
Casos
2 casos conhecidos
CID-10
A20.0 · Peste bubônica
CID-11
Ensaios
3 ativos
Início
All ages
Prevalência
0.0 (Worldwide)
MedGen
UMLS
C0032064
Repurposing
2 candidatos
levofloxacinbacterial DNA gyrase inhibitor
tetracyclinebacterial 30S ribosomal subunit inhibitor
EuropePMC
Wikidata
Wikipedia
Papers 10a
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