Raras
Buscar doenças, sintomas, genes...
Polirradiculoneuropatia inflamatória aguda (aidp)
ORPHA:98916CID-10 · G61.0CID-11 · 8C01.0DOENÇA RARA

É uma inflamação que atinge os nervos e faz parte do conjunto de problemas relacionados à Síndrome de Guillain-Barré (SGB).

Mantido por Agente Raras·Colaborar como especialista →

Introdução

O que você precisa saber de cara

📋

É uma inflamação que atinge os nervos e faz parte do conjunto de problemas relacionados à Síndrome de Guillain-Barré (SGB).

Pesquisas ativas
4 ensaios
89 total registrados no ClinicalTrials.gov
Publicações científicas
278 artigos
Último publicado: 2026 Feb 26

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
1-9 / 100 000
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
3.1
Europe
Início
All ages
🏥
SUS: Cobertura mínimaScore: 15%
CID-10: G61.0
🇧🇷Dados SUS / DATASUS
PROCEDIMENTOS SIGTAP (2)
0202010694
Sequenciamento completo do exoma (WES)genetic_test
0301070040
Atendimento em reabilitação — doenças rarasrehabilitation
Você se identifica com essa condição?
O Raras está aqui pra te apoiar — com ou sem diagnóstico

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Entender a doença

Do básico ao detalhe, leia no seu ritmo

Preparando trilha educativa...

Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🧠
Neurológico
4 sintomas
💪
Músculos
1 sintomas
😀
Face
1 sintomas

+ 7 sintomas em outras categorias

Características mais comuns

100%prev.
Polineuropatia desmielinizante aguda
55%prev.
Febre recorrente
Frequente (79-30%)
55%prev.
Fraqueza muscular distal do membro inferior
Frequente (79-30%)
55%prev.
Disestesia
Frequente (79-30%)
55%prev.
Hiporreflexia
Frequente (79-30%)
55%prev.
Hipotonia generalizada
Frequente (79-30%)
13sintomas
Muito frequente (1)
Frequente (10)
Ocasional (1)
Sem dados (1)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 13 características clínicas mais associadas, ordenadas por frequência.

Polineuropatia desmielinizante agudaAcute demyelinating polyneuropathy
Muito frequente100%
Febre recorrenteRecurrent fever
Frequente (79-30%)55%
Fraqueza muscular distal do membro inferiorDistal lower limb muscle weakness
Frequente (79-30%)55%
DisestesiaDysesthesia
Frequente (79-30%)55%
HiporreflexiaHyporeflexia
Frequente (79-30%)55%

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico278PubMed
Últimos 10 anos153publicações
Pico202123 papers
Linha do tempo
2026Hoje · 2026🧪 1995Primeiro ensaio clínico📈 2021Ano de pico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

Genes associados

1 gene identificado com associação a esta condição. Padrão de herança: Multigenic/multifactorial, Not applicable.

PMP22Peroxisomal membrane protein 2Major susceptibility factor inAltamente restrito
FUNÇÃO

Seems to be involved in pore-forming activity and may contribute to the unspecific permeability of the peroxisomal membrane

LOCALIZAÇÃO

Peroxisome membrane

VIAS BIOLÓGICAS (1)
EGR2 and SOX10-mediated initiation of Schwann cell myelination
EXPRESSÃO TECIDUAL(Ubíquo)
Nervo tibial
3229.9 TPM
Tecido adiposo
421.5 TPM
Cervix Ectocervix
415.8 TPM
Fallopian Tube
379.8 TPM
Cervix Endocervix
354.6 TPM
OUTRAS DOENÇAS (7)
Roussy-Levy syndromeCharcot-Marie-Tooth disease type 3hereditary neuropathy with liability to pressure palsiesCharcot-Marie-Tooth disease type 1E
HGNC:9118UniProt:Q9NR77

Medicamentos aprovados (FDA)

1 medicamento encontrado nos registros da FDA americana.

💊 GALLIUM CITRATE GA-67 (GALLIUM CITRATE GA-67)
Ver no DailyMed/FDA

Variantes genéticas (ClinVar)

292 variantes patogênicas registradas no ClinVar.

🧬 PMP22: GRCh38/hg38 17p12(chr17:14174654-15579519)x1 ()
🧬 PMP22: GRCh38/hg38 17p12(chr17:14170219-15510549)x3 ()
🧬 PMP22: GRCh38/hg38 17p12(chr17:14184601-15581021)x1 ()
🧬 PMP22: GRCh38/hg38 17p12(chr17:14174654-15536883)x3 ()
🧬 PMP22: GRCh38/hg38 17p12(chr17:14191318-15520772)x3 ()
Ver todas no ClinVar

Vias biológicas (Reactome)

2 vias biológicas associadas aos genes desta condição.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
·Pré-clínico4
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 4 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Polirradiculoneuropatia inflamatória aguda (aidp)

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

🟢 Recrutando agora

2 pesquisas recrutando participantes. Converse com seu médico sobre a possibilidade de participar.

Outros ensaios clínicos

89 ensaios clínicos encontrados, 4 ativos.

Distribuição por fase
Ver todos no ClinicalTrials.gov
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Divulgue para pacientes e familiares que acompanham esta doença.
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Publicações mais relevantes

Timeline de publicações
154 papers (10 anos)
#1

Axonal Versus Demyelinating Guillain-Barré Syndrome Subtypes in Critically Ill Children: Clinical and Autonomic Profiles.

Pediatric neurology2026 Feb

Electrophysiological subtypes of Guillain-Barré Syndrome (GBS) vary in pathophysiology and clinical presentation, but comparative data on their intensive care needs in critically ill children remain limited. In this retrospective cohort study, we analyzed 224 children (1 month to 12 years) diagnosed with GBS and admitted to the Pediatric Intensive Care Unit of a tertiary care hospital in North India from January 2010 to December 2022. GBS was subtyped based on nerve conduction studies into acute motor axonal neuropathy (AMAN), acute inflammatory demyelinating polyradiculoneuropathy (AIDP), acute motor-sensory axonal neuropathy (AMSAN), inexcitable, or equivocal patterns. Clinical features, intensive care interventions, and outcomes were compared across subtypes. AMAN was the most common subtype (61.6%), followed by AIDP (20.1%) and AMSAN (8%). A prodromal illness was reported in 47.3% of cases. Mechanical ventilation was required in 54.9%, and tracheostomy in 24.2% of children. AMSAN was associated with a significantly longer duration of symptoms at presentation (P = 0.006). Autonomic instability, particularly hypertension (P = 0.04), was significantly more frequent in the AIDP group. However, Hughes disability scores, respiratory and cranial nerve involvement, and intensive care needs were similar across subtypes. AMAN was the predominant GBS subtype in critically ill children. While AMSAN was associated with delayed presentation and AIDP with greater autonomic dysfunction, overall intensive care needs and short-term outcomes were comparable across subtypes.

#2

Case Report: Complete remission of Guillain-Barré syndrome in neuropsychiatric lupus with telitacicept.

Frontiers in immunology2026

Neuropsychiatric systemic lupus erythematosus (NPSLE) manifesting as Guillain-Barré syndrome (GBS) is exceptionally rare, with only 28 documented cases in medical literature, and current biological therapies show limited efficacy. We report a 34-year-old woman who presented with progressive quadriparesis, bilateral ptosis, and facial palsy developing over one month. Laboratory investigations revealed marked B-cell dysregulation with elevated immunoglobulin G (24.30 g/L, normal 7-16), positive antinuclear antibodies (1:320), anti-double-stranded DNA antibodies (128 IU/ml, normal <20), anti-ribosomal P antibodies (450 AU/ml, normal <20), and hypocomplementemia (C3 1.10 g/L, C4 0.28 g/L). Cerebrospinal fluid analysis showed cytoalbuminologic dissociation (protein 1314 mg/L, cells 1×106/L), and nerve conduction studies confirmed acute inflammatory demyelinating polyradiculoneuropathy. Following inadequate response to intravenous immunoglobulin monotherapy, combination treatment was initiated with methylprednisolone (40mg daily), cyclophosphamide (0.6g biweekly), hydroxychloroquine, and telitacicept (160mg weekly), a novel dual inhibitor of B lymphocyte stimulator and a proliferation-inducing ligand that simultaneously targets B cells and plasma cells. At six-month follow-up, the patient achieved complete neurological recovery with significant laboratory improvements: immunoglobulin G decreased 61.6% to 9.34 g/L, anti-double-stranded DNA antibodies decreased 82.8% to 22 IU/ml, erythrocyte sedimentation rate normalized from 63 to 8 mm/h, and complement levels recovered. Corticosteroids were successfully tapered to 4mg daily without disease flare. This first report of telitacicept use in NPSLE-GBS demonstrates that dual BLyS/APRIL inhibition can achieve complete remission in refractory cases, offering a promising therapeutic approach that warrants further investigation in controlled trials.

#3

Acute Inflammatory Demyelinating Polyradiculoneuropathy-like Associated with Subcutaneous Foslevodopa-Foscarbidopa: First Report.

Movement disorders : official journal of the Movement Disorder Society2026 Feb 26
#4

Polyradiculoneuropathies associated with immune checkpoint inhibitors: are we facing a new nosological entity?

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2025 Dec

Immune checkpoint inhibitors (ICIs) like ipilimumab, nivolumab, and pembrolizumab are increasingly used to treat advanced cancers. While they improve survival, they can cause immune-related adverse events (irAEs), including neurological issues affecting the peripheral nervous system (PNS). Among these, peripheral neuropathies such as acute inflammatory demyelinating polyneuropathy (AIDP) and chronic inflammatory demyelinating polyneuropathy (CIDP) are common. Diagnosing these conditions can be difficult, especially when caused by ICIs, leading to potential misclassification and suboptimal treatment. A 48-year-old woman with melanoma on pembrolizumab developed progressive weakness, sensory disturbances, and areflexia after two cycles of treatment. Neurological evaluation suggested AIDP, and she was treated with intravenous immunoglobulin (IVIg), which led to initial improvement. However, 60 days later, she relapsed with widespread weakness, and her condition was reclassified as acute-onset CIDP (A-CIDP). This case illustrates the challenge of distinguishing ICI-related AIDP from A-CIDP and the importance of accurate, early diagnosis and treatment. A review of the Literature found 51 AIDP and 10 CIDP cases related to ICIs. Symptoms commonly included weakness, paresthesia, and gait instability, with electromyography and nerve conduction studies often showing demyelinating patterns. Most patients were treated with steroids or IVIg, with significant recovery, though some AIDP cases relapsed or progressed, resembling A-CIDP. This highlights the risk of misdiagnosis in patients with ICI-related AIDP/CIDP. This case underscores the complexities of diagnosing ICI-related neuropathies, especially A-CIDP. Early cessation of ICI therapy and prompt immunosuppressive treatment are essential to prevent long-term disability.

#5

Plasma periaxin is a biomarker of peripheral nerve demyelination.

Brain : a journal of neurology2025 Dec 04

Assessing disease progression and informing clinical trials in peripheral neuropathy would benefit from objective and responsive fluid biomarkers closely linked to disease biology. This is particularly important in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and Guillain-Barré syndrome (GBS), the most common inflammatory neuropathies, where reliable biomarkers of peripheral demyelination would help identify, and potentially measure, active disease and responses to treatment. We postulated that periaxin, a protein exclusively expressed by myelinating Schwann cells, could serve as a fluid biomarker of demyelinating peripheral neuropathy. We developed a single molecule array (Simoa)-based immunoassay to measure plasma periaxin in patients with CIDP (n = 45, including longitudinal samples across a discovery cohort and a validation cohort, for a total of 77 time points), GBS (n = 30, 66 time points), Charcot-Marie-Tooth disease (CMT, n = 20), CNS disease controls with multiple sclerosis (n = 30) and healthy controls (n = 30). We also evaluated whether periaxin is released in myelinating co-cultures following immune-mediated demyelination and axonal damage, comparing results with uninjured cultures. Plasma periaxin effectively distinguishes peripheral from CNS diseases, with significantly elevated levels in CIDP, GBS and CMT, but not in CNS disease or healthy controls (all P < 0.01). In CIDP, periaxin discriminates patients with active disease from those with inactive disease (P < 0.0001), and plasma levels decrease following treatment with intravenous immunoglobulin (IVIg). Elevated periaxin strongly predicts clinical worsening at 1 year [sensitivity 99%, specificity 72%, area under the curve (AUC) 0.86 (95% confidence interval, CI: 0.67-1)]. In GBS, peak levels of plasma periaxin and the ratio of periaxin to axonal biomarkers [neurofilament light chain (NfL) and peripherin] discriminate most cases of acute inflammatory demyelinating polyradiculoneuropathy (AIDP) from acute motor axonal neuropathy (AMAN), as classified by electrophysiology (sensitivity 100%, specificity 86%, AUC = 0.94, 95% CI: 0.81-1). Serial measurements showed that plasma periaxin levels peak 2 to 3 weeks after GBS symptom onset, followed by a gradual decline in the weeks thereafter. In vitro, periaxin is higher following immune-mediated demyelination compared with axonal damage and control conditions. Plasma periaxin is a biomarker of peripheral nerve demyelination. Combined with axonal fluid biomarkers and existing clinical scales, periaxin has the potential to improve the clinical management of peripheral neuropathies, accelerating advances in care and experimental research.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC41 artigos no totalmostrando 151

2026

Acute Inflammatory Demyelinating Polyradiculoneuropathy-like Associated with Subcutaneous Foslevodopa-Foscarbidopa: First Report.

Movement disorders : official journal of the Movement Disorder Society
2026

Case Report: Complete remission of Guillain-Barré syndrome in neuropsychiatric lupus with telitacicept.

Frontiers in immunology
2025

Early Sensory-Predominant Guillain-Barré Syndrome With Normal Cerebrospinal Fluid and MRI Findings: A Diagnostic Challenge.

Cureus
2025

Systemic Lupus Erythematosus With Acute Inflammatory Demyelinating Polyneuropathy in Pregnancy: A Rare Multisystem Presentation.

Cureus
2026

Axonal Versus Demyelinating Guillain-Barré Syndrome Subtypes in Critically Ill Children: Clinical and Autonomic Profiles.

Pediatric neurology
2025

Bilateral Medial Medulla Infarct Mimicking a Neuromuscular Emergency.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
2025

Clinical Spectrum and Prognostic Predictors of Guillain-Barré Syndrome: A Prospective Observational Study From South India.

Cureus
2025

An Uncommon Presentation of Guillain-Barré Syndrome in a Young Postpartum Woman.

Cureus
2025

Guillain-Barré Syndrome as the Initial Clinical Manifestation of Hodgkin's Lymphoma.

European journal of case reports in internal medicine
2025

Peripheral nerve-targeting and pain-promoting transcriptomic signatures in early Guillain-Barré syndrome.

bioRxiv : the preprint server for biology
2025

Polyradiculoneuropathies associated with immune checkpoint inhibitors: are we facing a new nosological entity?

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2025

Plasma periaxin is a biomarker of peripheral nerve demyelination.

Brain : a journal of neurology
2025

Evaluation and Comparison of Treatment Response and In-Hospital Prognosis of COVID-19-Related Guillain-Barre Syndrome with Non-COVID-19 Patients.

Medical journal of the Islamic Republic of Iran
2025

Guillain-Barré Syndrome Induced by Mycoplasma Pneumoniae: A Non-classical Presentation.

Cureus
2025

Altered Cellular Pathways in the Blood of Patients With Guillain-Barre Syndrome.

Journal of the peripheral nervous system : JPNS
2025

Onset of Guillain Barré Syndrome in a Pregnant Woman: A Report of a Rare Occurrence.

Cureus
2025

Predictors of the Short-Term Outcomes of Guillain-Barré Syndrome: Exploring Electrodiagnostic and Clinical Features.

Brain and behavior
2025

An Uncommon Presentation of Guillain-Barré Syndrome With Lhermitte Sign.

Cureus
2024

The Initial Clinical and Electrophysiological Characteristics of Different Subtypes of Guillain-Barré Syndrome Diagnosed Based on Serial Electrophysiological Examinations.

Brain and behavior
2024

Temporal Pattern of Individual Neurological Function Recovery in Guillain-Barré Syndrome.

Journal of clinical medicine
2024

Guillain-Barrè Syndrome-Retrospective Analysis of Data from a Cohort of Patients Referred to a Tertiary Care Pediatric Neuromuscular Center from 2000 to 2017: Electrophysiological Findings, Outcomes, and a Brief Literature Review.

Medicina (Kaunas, Lithuania)
2024

Complex Neurological Sequelae: Axonal Guillain-Barré Syndrome Post COVID-19 in a Young Patient.

Cureus
2024

Unraveling the neurological intricacies: a rare case of Guillain-Barre syndrome in dengue fever.

Oxford medical case reports
2024

Expanding our understanding of Guillain-Barré syndrome: Recent advances and clinical implications.

European journal of immunology
2024

Management of Severe Pain in a Case of Sensory Guillain-Barre Syndrome.

Cureus
2024

Multiple cerebral infarctions after intravenous immunoglobulin for Guillain-Barré syndrome: two case reports and review of the literature.

Frontiers in immunology
2024

Animal models of immune-mediated demyelinating polyneuropathies.

Autoimmunity
2024

Guillain-Barré syndrome: History, pathogenesis, treatment, and future directions.

European journal of neurology
2024

The sural-sparing pattern in clinical variants and electrophysiological subtypes of Guillain-Barré syndrome.

Arquivos de neuro-psiquiatria
2024

Rehabilitation of a 51-Year-Old Patient With Miller Fisher Syndrome: A Case Report.

Cureus
2024

Guillain-Barre syndrome of acute motor axonal neuropathy (AMAN) type associated with herpes zoster: a case report.

BMC neurology
2024

Guillain-Barré syndrome after COVID-19 vaccination: A systematic review and analysis of case reports.

Clinical neurology and neurosurgery
2023

Aggressive Acquired Demyelinating Neuropathy Caused by NF-155: Initially Treatment-Resistant.

Journal of clinical neuromuscular disease
2023

Guillain-Barré Syndrome Associated with SARS-CoV-2 in Two Pediatric Patients.

Sultan Qaboos University medical journal
2023

Incidence of Guillain-Barré syndrome in the world between 1985 and 2020: A systematic review.

Global epidemiology
2023

Plasmapheresis Versus Intravenous Immunoglobulin in Patients With Autoimmune Neuromuscular and Neuro-immunological Conditions.

Journal of clinical neuromuscular disease
2023

Acute/chronic inflammatory polyradiculoneuropathy.

Handbook of clinical neurology
2023

Clinical characteristics and management outcomes of Guillain-Barré syndrome: eight-year experience at a tertiary center in jordan - a retrospective cohort study.

Annals of medicine and surgery (2012)
2023

Sympathetic skin response (SSR) in pediatric Guillain-Barré syndrome.

Frontiers in neurology
2024

Pathology explains various mechanisms of auto-immune inflammatory peripheral neuropathies.

Brain pathology (Zurich, Switzerland)
2023

Principles of Therapeutic Apheresis in Neurological Disease.

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie
2022

Leptomeningeal carcinomatosis presenting with acute motor axonal neuropathy.

Indian journal of cancer
2023

Changes in electrophysiological findings suggestive of demyelination following Guillain-Barré syndrome: A retrospective study.

Muscle &amp; nerve
2023

Guillain-Barré syndrome after COVID-19 vaccines: A Tunisian case series.

British journal of clinical pharmacology
2022

Spectrum of Neurological Complications Following COVID-19 Vaccination in India.

Journal of clinical neurology (Seoul, Korea)
2022

Prognostic Significance of Serial Nerve Conduction in GB Syndrome.

Neurology India
2022

Elevated monocyte to high-density lipoprotein cholesterol ratio correlates with clinical severity in acute inflammatory demyelinating polyradiculoneuropathy patients.

Frontiers in neurology
2022

[Guillain-Barré syndrome and other autoimmune neurophaties: current therapy].

Medicina
2022

Assessment of neurological sequelae and new-onset symptoms in the long-term follow-up of paediatric Guillain-Barre syndrome: A longitudinal study from India.

Journal of paediatrics and child health
2022

Pembrolizumab-Induced Myocarditis and Delayed Acute Inflammatory Demyelinating Polyradiculoneuropathy.

Cureus
2022

A case of Guillain-Barre syndrome after the second dose of AstraZeneca COVID-19 vaccination.

Turkish journal of physical medicine and rehabilitation
2022

Outcome of Guillain-Barré syndrome following intravenous immunoglobulin compared to natural course.

European journal of neurology
2022

COVID-19 vaccine-related Guillain-Barré syndrome in the Liguria region of Italy: A multicenter case series.

Journal of the neurological sciences
2021

Guillain-Barré syndrome in patients with SARS-CoV-2 infection. Report of three cases.

Revista medica de Chile
2022

Neurologic Sequela of COVID-19: Guillain-Barré Syndrome Following Johnson & Johnson COVID-19 Vaccination.

Cureus
2022

Post-COVID-19 Longitudinally Extensive Transverse Myelitis with Myelin Oligodendrocyte Glycoprotein Antibodies.

Case reports in neurological medicine
2022

Serum thyroid-stimulating hormone is an independent risk factor of recurrent Guillain-Barré syndrome.

Muscle &amp; nerve
2022

COVID-19 Infection and Guillain-Barre Syndrome: A Case Series.

Cureus
2022

Late-Onset Guillain-Barré Syndrome and Right Facial Nerve Palsy after COVID-19 Infection.

Case reports in neurology
2021

COVID-19-Induced Guillain-Barré Syndrome.

Cureus
2022

Immunoadsorption and plasma exchange-Efficient treatment options for neurological autoimmune diseases.

Journal of clinical apheresis
2022

Guillain-Barré syndrome following the first dose of Pfizer-BioNTech COVID-19 vaccine: case report and review of reported cases.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2021

Covid-19 associated Guillain-Barré syndrome: A series of a relatively uncommon neurological complication.

Diabetes &amp; metabolic syndrome
2021

Guillain-Barre syndrome during COVID-19 pandemic: experience from a referral healthcare center in Mexico.

Revista de neurologia
2021

Acute Inflammatory Demyelinating Polyneuropathy With Bowel and Bladder Incontinence Following COVID-19 Infection.

Cureus
2021

Bilateral Facial Palsy and Hyperreflexia as the Main Clinical Presentation in Guillain-Barré Syndrome.

The American journal of case reports
2021

Relationship between cerebrospinal fluid protein level and electrophysiologic abnormalities in the acute inflammatory demyelinating polyradiculoneuropathy variant of Guillain-Barré syndrome.

German medical science : GMS e-journal
2021

Incidence and clinical characteristics of Guillain-Barré syndrome in Osona (Barcelona, Spain), 2003-2016.

Neurologia
2021

Development of Acute Inflammatory Demyelinating Polyneuropathy 11 Days after Spinal Surgery: A Case Report and Literature Review.

Case reports in medicine
2021

Epidemiological and clinical aspects of Guillain-Barré syndrome and its variants.

Arquivos de neuro-psiquiatria
2021

Clinical features and outcome of Guillain-Barre syndrome in Saudi Arabia: a multicenter, retrospective study.

BMC neurology
2021

Case Report: Guillain-Barré Syndrome Associated With COVID-19.

Frontiers in neurology
2022

Therapeutic plasma exchange in neurological diseases: Eleven years experience at a tertiary care center in Turkey.

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy
2021

Guillain-Barré Syndrome With a Peculiar Course: A Case Report.

Cureus
2021

Electrophysiological characteristics of patients with nitrous oxide abuse.

Neurological research
2021

Functional Impairments and Rehabilitation Outcomes of Patients With Immunotherapy-Induced Acute Inflammatory Demyelinating Polyradiculoneuropathy, Myasthenia Gravis, and Myositis.

American journal of physical medicine &amp; rehabilitation
2021

Clinical and Electrophysiological Outcome Measures of Patients With Post-Infectious Neurological Syndromes Related to COVID-19 Treated With Intensive Neurorehabilitation.

Frontiers in neurology
2021

Electrophysiological features of acute inflammatory demyelinating polyneuropathy associated with SARS-CoV-2 infection.

Neurophysiologie clinique = Clinical neurophysiology
2021

Immune-mediated neuromuscular complications of graft-versus-host disease.

Muscle &amp; nerve
2021

Creutzfeldt-Jakob Disease May Present Early With Unusual Bulbar Predominance.

The neurologist
2020

Frequency of Autonomic Dysfunction in Patients of Guillain Barre Syndrome in a Tertiary Care Hospital.

Cureus
2021

Late onset of Guillain-Barré syndrome following SARS-CoV-2 infection: part of 'long COVID-19 syndrome'?

BMJ case reports
2021

Guillain Barré Syndrome and its variants as a manifestation of COVID-19: A systematic review of case reports and case series.

Journal of the neurological sciences
2021

CSF sphingomyelin: a new biomarker of demyelination in the diagnosis and management of CIDP and GBS.

Journal of neurology, neurosurgery, and psychiatry
2020

Acute inflammatory demyelinating polyradiculoneuropathy following deep brain stimulator lead placement - Case report and review of the literature.

Clinical neurology and neurosurgery
2020

COVID-19: A Review for the Pediatric Neurologist.

Journal of child neurology
2021

Is Guillain-Barrè syndrome triggered by SARS-CoV-2? Case report and literature review.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2020

Clinical Characteristics and Electrodiagnostic Features of Guillain-Barré Syndrome Among the Pediatric Population.

Journal of child neurology
2019

Clinical, electrophysiological findings and evaluation of prognosis of patients with Guillain-Barré syndrome.

The Turkish journal of pediatrics
2019

Recurrent Guillain-Barré Syndrome - Case Series.

Neurology India
2020

Guillain-Barré syndrome: clinical features, treatment choices and outcomes in an Australian cohort.

Internal medicine journal
2019

Prognostic factors for the sequelae and severity of Guillain-Barré syndrome in children.

Muscle &amp; nerve
2019

Clinical and electrophysiological characteristics of Guillain-Barré syndrome in Colombia.

Journal of the peripheral nervous system : JPNS
2020

Dysautonomia in Guillain-Barré Syndrome: Prevalence, Clinical Spectrum, and Outcomes.

Neurocritical care
2019

Nivolumab and Ipilimumab-induced Acute Inflammatory Demyelinating Polyradiculoneuropathy: A Case Report.

Journal of immunotherapy (Hagerstown, Md. : 1997)
2019

Coincidence of Guillain-Barré syndrome presenting with Landry's acute flaccid paralysis and transverse myelitis.

Reumatologia
2019

Postoperative Guillain-Barré Syndrome, a Neurologic Complication that Must Not Be Overlooked: A Literature Review.

World neurosurgery
2019

Therapeutic apheresis in neurological, nephrological and gastrointestinal diseases.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
2019

Role of IV Immunoglobulin in Indian Children With Guillain-Barré Syndrome.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
2019

Dry Beriberi Due to Thiamine Deficiency Associated with Peripheral Neuropathy and Wernicke's Encephalopathy Mimicking Guillain-Barré syndrome: A Case Report and Review of the Literature.

The American journal of case reports
2019

Guillain-Barré syndrome as a complication of hypertensive basal ganglia haemorrhage.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
2019

Atypical Clinical Presentations of Pediatric Acute Immune-Mediated Polyneuropathy.

Journal of child neurology
2018

The effects of vasoactive intestinal peptide in the rat model of experimental autoimmune neuritis and the implications for treatment of acute inflammatory demyelinating polyradiculoneuropathy or Guillain-Barré syndrome.

Drug design, development and therapy
2019

Systematic review of factors associated with the development of Guillain-Barré syndrome 2007-2017: what has changed?

Tropical medicine &amp; international health : TM &amp; IH
2019

Increased incidence of axonal Guillain-Barré syndrome in La Spezia area of Italy: A 13-year follow-up study.

Journal of the peripheral nervous system : JPNS
2018

The electrodiagnosis of Guillain-Barré syndrome subtypes: Where do we stand?

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
2018

Antibodies to Zika virus, Campylobacter jejuni and gangliosides in Guillain-Barre syndrome: A prospective single-center study from southern India.

Neurology India
2018

Epidemiology and Clinical Features of Guillain-Barre Syndrome in Isfahan, Iran.

Advanced biomedical research
2018

Motor Nerve Conduction Block Predicting Outcome of Guillain-Barre Syndrome.

Frontiers in neurology
2018

Clinical Significance of A Waves in Acute Inflammatory Demyelinating Polyradiculoneuropathy.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society
2019

Peripheral nervous system involvement in systemic lupus erythematosus: a review of the evidence.

Clinical and experimental rheumatology
2018

Patient with Guillain-Barré Syndrome with Posterior Spinal Root Involvement: A Case Report.

Sisli Etfal Hastanesi tip bulteni
2018

Guillain-BarrÉ syndrome subtype diagnosis: A prospective multicentric European study.

Muscle &amp; nerve
2018

Clinical and nerve conduction features in Guillain-Barré syndrome associated with Zika virus infection in Cúcuta, Colombia.

European journal of neurology
2017

Outcome of Guillain-Barré Syndrome in Tertiary Care Centers in Thailand.

Journal of clinical neuromuscular disease
2017

Early electrophysiological findings in acute inflammatory demyelinating polyradiculoneuropathy variant of Guillain-Barre syndrome in the Pakistani population - a comparison with global data.

Journal of the peripheral nervous system : JPNS
2018

Prospective comparison of acute motor axonal neuropathy and acute inflammatory demyelinating polyradiculoneuropathy in 140 children with Guillain-Barré syndrome in India.

Muscle &amp; nerve
2017

Worsening Guillain-Barré syndrome: harbinger of IRIS in HIV?

BMJ case reports
2018

[Lower urinary tract dysfunction in Guillain-Barre syndrome].

Der Urologe. Ausg. A
2018

Acute Inflammatory Demyelinating Polyradiculoneuropathy Secondary to Ifosfamide.

American journal of therapeutics
2017

Hepatitis E virus and neurological disorders.

Practical neurology
2017

Three cases of acute distal demyelinating neuropathy with recovery.

Clinical case reports
2017

Optimizing the electrodiagnostic accuracy in Guillain-Barré syndrome subtypes: Criteria sets and sparse linear discriminant analysis.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
2017

Analysis of serum interleukin-27 and interleukin-35 concentrations in patients with Guillain-Barré syndrome.

Clinica chimica acta; international journal of clinical chemistry
2016

Outcome of Guillain - Barré Syndrome in Children: A prospective cohort study in a tertiary hospital in Upper Egypt.

Electronic physician
2017

Prevalence of autonomic dysfunction in hospitalized patients with Guillain-Barré syndrome.

Muscle &amp; nerve
2017

Differentiating Familial Neuropathies from Guillain-Barré Syndrome.

Pediatric clinics of North America
2016

Co-Cccurrence of Guillain-Barre Syndrome and Primary Sjögren Syndrome in an Elderly Woman.

Acta neurologica Taiwanica
2016

The pathogenic relevance of αM-integrin in Guillain-Barré syndrome.

Acta neuropathologica
2016

Analysis of the albumin level, neutrophil-lymphocyte ratio, and platelet-lymphocyte ratio in Guillain-Barré syndrome.

Arquivos de neuro-psiquiatria
2016

Pediatric Miller Fisher Syndrome Complicating an Epstein-Barr Virus Infection.

Pediatric neurology
2016

Nivolumab-induced chronic inflammatory demyelinating polyradiculoneuropathy mimicking rapid-onset Guillain-Barré syndrome: a case report.

Japanese journal of clinical oncology
2016

Prognosis of Guillain-Barré Syndrome in Children.

Iranian journal of child neurology
2016

Acute inflammatory demyelinating polyradiculoneuropathy in a newborn infant.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
2016

Acute Motor Axonal Neuropathy (Aman) With Motor Conduction Blocks In Childhood; Case Report.

Iranian journal of child neurology
2016

Supernumerary phantom limbs in ICU patients with acute inflammatory demyelinating polyneuropathy.

Neurology
2016

Acute Bilateral Phrenic Neuropathy: from Diabetes Mellitus to Focal Guillain-Barré Syndrome.

Maedica
2016

A comparison between plasmapheresis and intravenous immunoglobulin in children with Guillain-Barré syndrome in Upper Egypt.

Therapeutic advances in neurological disorders
2016

Alternating ptosis associated with asialo-GM1 and GD1b antibodies.

The International journal of neuroscience
2015

[Facial diplegia as unusual variant of Guillain-Barré syndrome: first case reported in Venezuela].

Investigacion clinica
2015

[Pathology of the Peripheral Nervous System in Guillain-Barré Syndrome].

Brain and nerve = Shinkei kenkyu no shinpo
2016

Sural sparing in Guillain-Barré syndrome subtypes: a reappraisal with historical and recent definitions.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
2015

Guillain-Barré syndrome: clinical profile and management.

German medical science : GMS e-journal
2015

Inflammatory neuropathies: pathology, molecular markers and targets for specific therapeutic intervention.

Acta neuropathologica
2015

Pupils in Acute Inflammatory Demyelinating Polyradiculoneuropathy Different From Adies Pupils.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
2015

Severe acute inflammatory demyelinating polyradiculoneuropathy with persistent weakness associated with tumor-like nerve root enlargement.

Journal of clinical neuromuscular disease
2015

Acute Onset of Guillain-Barré Syndrome After Elective Spinal Surgery.

World neurosurgery
2015

Peripheral neuropathies due to systemic lupus erythematosus in China.

Medicine
2015

Guillain-Barré syndrome (demyelinating) six weeks after bariatric surgery: A case report and literature review.

Obesity research &amp; clinical practice
2015

Pediatric Guillain-Barré syndrome: Indicators for a severe course.

Annals of Indian Academy of Neurology
2015

Guillain-barré syndrome: a clinical study of twenty children.

Journal of clinical and diagnostic research : JCDR

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Comunidades

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Doenças relacionadas

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Axonal Versus Demyelinating Guillain-Barr&#xe9; Syndrome Subtypes in Critically Ill Children: Clinical and Autonomic Profiles.
    Pediatric neurology· 2026· PMID 41389764mais citado
  2. Case Report: Complete remission of Guillain-Barr&#xe9; syndrome in neuropsychiatric lupus with telitacicept.
    Frontiers in immunology· 2026· PMID 41659868mais citado
  3. Acute Inflammatory Demyelinating Polyradiculoneuropathy-like Associated with Subcutaneous Foslevodopa-Foscarbidopa: First Report.
    Movement disorders : official journal of the Movement Disorder Society· 2026· PMID 41748281mais citado
  4. Polyradiculoneuropathies associated with immune checkpoint inhibitors: are we facing a new nosological entity?
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology· 2025· PMID 41021157mais citado
  5. Plasma periaxin is a biomarker of peripheral nerve demyelination.
    Brain : a journal of neurology· 2025· PMID 40581376mais citado
  6. Early Sensory-Predominant Guillain-Barré Syndrome With Normal Cerebrospinal Fluid and MRI Findings: A Diagnostic Challenge.
    Cureus· 2025· PMID 41503320recente
  7. Systemic Lupus Erythematosus With Acute Inflammatory Demyelinating Polyneuropathy in Pregnancy: A Rare Multisystem Presentation.
    Cureus· 2025· PMID 41450410recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:98916(Orphanet)
  2. MONDO:0020347(MONDO)
  3. GARD:16873(GARD (NIH))
  4. Variantes catalogadas(ClinVar)
  5. Busca completa no PubMed(PubMed)
  6. Q55346105(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Polirradiculoneuropatia inflamatória aguda (aidp)
Compêndio · Raras BR

Polirradiculoneuropatia inflamatória aguda (aidp)

ORPHA:98916 · MONDO:0020347
Prevalência
1-9 / 100 000
Herança
Multigenic/multifactorial, Not applicable
CID-10
G61.0 · Síndrome de Guillain-Barré
CID-11
Ensaios
4 ativos
Início
All ages
Prevalência
3.1 (Europe)
MedGen
UMLS
C1963929
EuropePMC
Wikidata
Papers 10a
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