Early Diagnosis and Targeted Therapy in SLC39A8-Congenital Disorder of Glycosylation: A Case Report From Bulgaria.

VPA targets Mid1 to improve disrupted retrograde axonal transport in hippocampal neurons and alleviate lithium manganate-induced learning and memory dysfunction.

SIRT3 attenuates chronic pain-induced depressive-like behaviors by deacetylating CypD at lysine 166 in central amygdala.

Neuron-specific modulation of SLC30A10 identifies dopaminergic and glutamatergic neurons as targets of manganese-induced motor disease.

Fine and ultrafine particulate matter components and autism spectrum disorder (ASD).

Gut to brain: essential micronutrient and trace element manganese transport, function and toxicity.

Excess Dietary Manganese Impairs Iron Nutrition via Modulating Duodenal Transporters in Weaned Pigs.

Manganese activates the CBASS immunity to protect bacteria from phage infection.

Mutagenesis of OsNRAMP5 Affects Blast Resistance Through Mn Absorption in Rice.

SLC11A2 affects nutritional immunity in the gut epithelium.

Discovery of a Selective Inhibitor of ZIP14 with Therapeutic Potential for Cancer-associated Cachexia.

A homology-based 3D model and structure-function studies reveal key elements for divalent metal ion transporter ZIP8 (SLC39A8) function.

EPR spectroscopy reveals antioxidant manganese defenses in the Lyme disease pathogen Borrelia burgdorferi.

Allosteric modulation of the solute carrier transporter SLC39A8 potentiates manganese and cadmium uptake.

Removal of Toxic Metabolites-Chelation: Manganese Disorders.

SLC39A14 is Required for Iron Loading of the Anterior Pituitary of Mice with Genetic Iron Overload.

Pulmonary Surfactant Protein-Hitchhiking Inhalable Vaccines Augment Mucosal and Systemic Antiviral Immunity.

Metal Transporter Gene SLC39A8 Polymorphism rs13107325 and Dietary Manganese Intake Are Associated with Measures of Cardiovascular Disease Risk in a UK Biobank Population Cohort.

Delayed emergence of parkinson's disease after reversible manganese-induced parkinsonism: a case report.

Epigenetic Regulation of Manganese-Induced Hepatotoxicity Uncovering Histone Demethylation-Associated Gene Networks.

Molecular mechanisms of SLC30A10-mediated manganese transport.

Cerebellar dysfunction in a mouse model of childhood-onset manganese-induced dystonia parkinsonism.

Systematic analysis of naturally occurring missense mutations in human manganese transporters: prediction and structural insights.

Aberrant N-glycosylation may be a therapeutic target in carriers of a common and highly pleiotropic variant in the manganese transporter ZIP8.

The role of redox-active iron, copper, manganese, and redox-inactive zinc in toxicity, oxidative stress, and human diseases.

An iPSC-derived neuronal model reveals manganese's role in neuronal endocytosis, calcium flux and mitochondrial bioenergetics.

Cholinergic dysfunction in occupational manganese exposure.

Nutritional Immunity in Wound Infection: Unveiling the Role of Dietary Elements in Host-Pathogen Interaction.

Impact of Manganese on Neuronal Function: An Exploratory Multi-Omics Study on Ferroalloy Workers in Brescia, Italy.

Beneficial Role of Resveratrol on Oxidative Stress in Women with Polycystic Ovary Syndrome: A Randomized Controlled Trial.

Mitochondria: Key Mediator for Environmental Toxicant-Induced Neurodegeneration.

Exploratory Metabolomic and Lipidomic Profiling in a Manganese-Exposed Parkinsonism-Affected Population in Northern Italy.

Mn-Doped CeO2 Nanozyme-Integrated Mesoporous Interfaces for High-Sensitivity Antifouling Electrochemiluminescence Biosensing.

Functional Cargo in Membrane Vesicles From a Citrus Pathogen.

The effect of TSPO transmembrane transport-mediated paeonol mitochondrial antioxidant on dexamethasone-induced mitochondrial abnormalities, oxidative stress damage, and apoptosis in SV40-MES-13 cells.

Prevalence of Restless Leg Syndrome and Its Association With Iron Deficiency in Patients With Chronic Kidney Disease: A Cross-Sectional Observational Study.

CAD (Cath. a-Differentiated) Cells Produce Dopamine along with Dopamine-Synthesizing Enzymes.

Sensitive detection of dengue serotype-4 on lignin-derived graphene nanofibre and manganese oxide composite by DNA-sensing.

Manganese Intoxication Induced by Total Parenteral Nutrition in the Intensive Care Unit: A Case Report.

Manganese-Induced Parkinsonism: A Review of Etiologies and Treatments.

Impact of Manganese on Neuronal Function: An Exploratory MultiOmic Study on Ferroalloy Workers in Brescia, Italy.

Magnetic Frameworks and Non-Magnetic Dopants: A Novel Strategy for Enhancing Thermoelectric Efficiency in Manganese Telluride - Mechanistic Insights into Charge Carrier Dynamics and Phonon Transport.

Cadmium exposure and its role in joint disease: A brief review of experimental and population-based evidence.

Consensus of Expert Opinion for the Diagnosis and Management of Hypermanganesaemia With Dystonia 1 and 2.

Manganese Neurotoxicity: A Comprehensive Review of Pathophysiology and Inherited and Acquired Disorders.

Acid-resistant chemotactic DNA micromotors for probiotic delivery in inflammatory bowel disease.

Canagliflozin potentially promotes renal protection against glycerol-induced acute kidney injury by activating the AMPK/SIRT1/FOXO-3a/PGC-1α and Nrf2/HO-1 pathways.

Streptococcus suis manganese transporter mutant as a live attenuated vaccine: Safety, efficacy, and virulence reversion mechanisms.

ROS-responsive MnO2 mesoporous hydrogel to modulate liver-muscle crosstalk and mitigate NAFLD-associated sarcopenia via exosomal miR-582-5p delivery.

Intracellular Mn mobility and differential response to H2O2 accumulation explain the susceptibility of litchi cultivars to dark pericarp disease.

SloR-SRE binding to the S. mutans mntH promoter is cooperative.

Calprotectin elicits aberrant iron starvation responses in Pseudomonas aeruginosa under anaerobic conditions.

Proximal tubular deletion of superoxide dismutase-2 reveals disparate effects on kidney function in diabetes.

Hypermagnesemia with Dystonia Type 2: Case Report of a New SLC30A10 Variant.

ZntR is a critical regulator for zinc homeostasis and involved in pathogenicity in Riemerella anatipestifer.

Electron Transfer-Driven Nanozymes Boost Biosensor Sensitivity via a Synergistic Signal Amplification Strategy.

ATP-Exhausted Strategy Induced Anti-Tumor Low-Temperature Photothermal Therapy Based on Rare Earth Nanocrystals Modified Hollow Porous MnOx Nanozyme with TME-Activated NIR-II Imaging.

Studies of Slc30a10 Deficiency in Mice Reveal That Intestinal Iron Transporters Dmt1 and Ferroportin Transport Manganese.

Protection of Mice Vaccinated with a New B Cell and T Cell Epitopes Cocktail from Staphylococcus aureus Challenge in Skin Infection Model.

Identification of key chromium resistance genes in Cellulomonas using transcriptomics.

Computational and experimental mapping of the allosteric network of two manganese ABC transporters.

Human genetic variants in SLC39A8 impact uptake and steady-state metal levels within the cell.

Sensitivity-enhanced self-powered biosensing platform for detection of sugarcane smut using Mn-doped ZIF-67, RCA-DNA nano-grid array and capacitor.

Biotin mitigates the development of manganese-induced, Parkinson's disease-related neurotoxicity in Drosophila and human neurons.

SLC10A7 regulates O-GalNAc glycosylation and Ca2+ homeostasis in the secretory pathway: insights into SLC10A7-CDG.

Manganese is a potent inducer of lysosomal activity that inhibits de novo HBV infection.

Silicon regulation of manganese homeostasis in plants: mechanisms and future prospective.

The Role of Trace Elements in COPD: Pathogenetic Mechanisms and Therapeutic Potential of Zinc, Iron, Magnesium, Selenium, Manganese, Copper, and Calcium.

Manganese Exposure Enhances the Release of Misfolded α-Synuclein via Exosomes by Impairing Endosomal Trafficking and Protein Degradation Mechanisms.

Targeting ROS in osteoclasts within the OA environment: A novel therapeutic strategy for osteoarthritis management.

Manganese: From Soil to Human Health-A Comprehensive Overview of Its Biological and Environmental Significance.

MATE transporter OsMATE2 mediates root growth, grain size and weight by interacting with Mn-SOD and PABP in rice.

Expression of Manganese Transporters ZIP8, ZIP14, and ZnT10 in Brain Barrier Tissues.

ZIP8 A391T Crohn's Disease-Linked Risk Variant Induces Colonic Metal Ion Dyshomeostasis, Microbiome Compositional Shifts, and Inflammation.

Pumping the Breaks on Acantholytic Skin Disorders: Targeting Calcium Pumps, Desmosomes, and Downstream Signaling in Darier, Hailey-Hailey, and Grover Disease.

Association of medullary reticular formation ventral part with spasticity in mice suffering from photothrombotic stroke.

Protection of cultured vascular endothelial cells against cadmium cytotoxicity by simultaneous treatment or pretreatment with manganese.

Manganese transporter SLC30A10 and iron transporters SLC40A1 and SLC11A2 impact dietary manganese absorption.

In vitro reconstitution of transition metal transporters.

Aberrant N-glycosylation is a therapeutic target in carriers of a common and highly pleiotropic mutation in the manganese transporter ZIP8.

Insights into molecular and cellular functions of the Golgi calcium/manganese-proton antiporter TMEM165.

Urine manganese, cadmium, lead, arsenic, and selenium among autism spectrum disorder children in Kuala Lumpur.

Elevated thyroid manganese reduces thyroid iodine to induce hypothyroidism in mice, but not rats, lacking SLC30A10 transporter.

The manganese transporter SLC39A8 links alkaline ceramidase 1 to inflammatory bowel disease.

Reduced Mn uptake of pleiotropic ZIP8 SNP is caused by its loss of Mn-responsive accumulation on the cell-surface.

Identification and characterization of zinc importers in Corynebacterium diphtheriae.

Manganese overexposure results in ferroptosis through the HIF-1α/p53/SLC7A11 pathway in ICR mouse brain and PC12 cells.

Does SLC39A8 Ala391Thr Confer Risk of Chronic Liver Disease?

Trace Elements in Alzheimer's Disease and Dementia: The Current State of Knowledge.

Hepatic HIF2 is a key determinant of manganese excess and polycythemia in SLC30A10 deficiency.

Prevalence rates of neurodegenerative diseases versus human exposures to heavy metals across the United States.

Optimizing nutrient transporters to enhance disease resistance in rice.

Ion Channels and Metal Ions in Parkinson's Disease: Historical Perspective to the Current Scenario.

Diagnosis of manganism and manganese neurotoxicity: A workshop report.

AAV-mediated hepatic expression of SLC30A10 and the Thr95Ile variant attenuates manganese excess and other phenotypes in Slc30a10-deficient mice.

Crohn's Disease-Associated Pathogenic Mutation in the Manganese Transporter ZIP8 Shifts the Ileal and Rectal Mucosal Microbiota Implicating Aberrant Bile Acid Metabolism.

Loss of SLC30A10 manganese transporter alters expression of neurotransmission genes and activates hypoxia-inducible factor signaling in mice.

ATP13A2 (PARK9) and basal ganglia function.

Manganese disrupts the maturation and degradation of axonal autophagosome leading to hippocampal synaptic toxicity in mice via the activation of LRRK2 on phosphorylation of Rab10.

Ferroptosis at the crossroads of manganese-induced neurotoxicity: A retrospective study.

The antioxidant and anti-inflammatory activities of avasopasem manganese in age-associated, cisplatin-induced renal injury.

Spatial distribution of trace metals and associated transport proteins during bacterial infection.

Biotin rescues manganese-induced Parkinson's disease phenotypes and neurotoxicity.

Filifactor alocis enhances survival of Porphyromonas gingivalis W83 in response to H2 O2 -induced stress.

Efficacy of oral manganese and D-galactose therapy in a patient bearing a novel TMEM165 variant.

Upregulated FOXM1 stimulates chondrocyte senescence in Acot12-/-Nudt7-/- double knockout mice.

Manganese regulation of COPII condensation controls circulating lipid homeostasis.

Manganese therapy for dyslipidemia and plaque reversal in murine models.

Blood-cerebrospinal fluid barrier permeability of metals/metalloids and its determinants in pediatric patients.

Dynamic elementomics of single-cell ICP-MS-derived signals in normal and calcium pump PMCA4-deficient mouse epididymal sperm during capacitation.

In vitro studies of manganese transport and homeostasis.

Impact of manganese accumulation on Na,K-ATPase expression and function in the cerebellum and striatum of C57Bl/6 mice.

Developmental Manganese Exposure Causes Lasting Attention Deficits Accompanied by Dysregulation of mTOR Signaling and Catecholaminergic Gene Expression in Brain Prefrontal Cortex.

Hepatic and intestinal manganese excretion are both required to regulate brain manganese during elevated manganese exposure.

Dietary Trace Elements and the Pathogenesis of Neurodegenerative Diseases.

New insights into the pathogenicity of TMEM165 variants using structural modeling based on AlphaFold 2 predictions.

Impact of an SLC30A8 loss-of-function variant on the pancreatic distribution of zinc and manganese: laser ablation-ICP-MS and positron emission tomography studies in mice.

The impact of nutritional immunity on Group B streptococcal pathogenesis during wound infection.

Photoelectrochemical detection of superoxide anions released from mitochondria in HepG2 cells based on the synergistic effect of MnO2@Co3O4 core-shell p-n heterojunction.

Functional Characterization of FeoAB in Iron Acquisition and Pathogenicity in Riemerella anatipestifer.

Essential Trace Elements in Patients with Dyslipidemia: A Meta-analysis.

Manganese (II) Complex of 1,4,7-Triazacyclononane-1,4,7-Triacetic Acid (NOTA) as a Hepatobiliary MRI Contrast Agent.

Insights into the regulation of cellular Mn2+ homeostasis via TMEM165.

Iron Limitation Restores Autophagy and Increases Lifespan in the Yeast Model of Niemann-Pick Type C1.

Copper Efflux System Required in Murine Lung Infection by Haemophilus influenzae Composed of a Canonical ATPase Gene and Tandem Chaperone Gene Copies.

SLC30A10 manganese transporter in the brain protects against deficits in motor function and dopaminergic neurotransmission under physiological conditions.

Influence of Environmental Exposure to Steel Waste on Endocrine Dysregulation and PER3 Gene Polymorphisms.

Linagliptin exacerbates heart failure due to energy deficiency via downregulation of glucose utilization and absorption in a mouse model.

Comparative analysis of the functional properties of human and mouse ferroportin.

Current insights into the microbial degradation of nicosulfuron: Strains, metabolic pathways, and molecular mechanisms.

Healthy dietary patterns are associated with the gut microbiome in the Hispanic Community Health Study/Study of Latinos.

Cryo-EM structures of human SPCA1a reveal the mechanism of Ca2+/Mn2+ transport into the Golgi apparatus.

Hypoxia-inducible factor 2 is a key determinant of manganese excess and polycythemia in SLC30A10 deficiency.

Manganese Efflux Achieved by MetA and MetB Affects Oxidative Stress Resistance and Iron Homeostasis in Riemerella anatipestifer.

Combined chronic copper exposure and aging lead to neurotoxicity in vivo.

Hypermanganesaemia with dystonia polycythemia and cirrhosis.

Biomineralized Nanoscavenger Abrogates Proinflammatory Macrophage Polarization and Induces Neutrophil Clearance through Reverse Migration during Gouty Arthritis.

Prenatal exposure to tailpipe and non-tailpipe tracers of particulate matter pollution and autism spectrum disorders.

Hormetic activation of nano-sized rare earth element terbium on growth, PSII photochemistry, antioxidant status and phytohormone regulation in Lemnaminor.

Generation of the Chemical and Social Stressors Integration Technique (CASS-IT) to identify areas of holistic public health concern: An application to North Carolina.

Manganese efflux transporter SLC30A10 missense polymorphism T95I associated with liver injury retains manganese efflux activity.

Hereditary Disorders of Manganese Metabolism: Pathophysiology of Childhood-Onset Dystonia-Parkinsonism in SLC39A14 Mutation Carriers and Genetic Animal Models.

Reprisal of Schima superba to Mn stress and exploration of its defense mechanism through transcriptomic analysis.

Caenorhabditis elegans as a Model to Study Manganese-Induced Neurotoxicity.

Foliar application of three dithiocarbamates inhibits the absorption and accumulation of Cd in wheat.

A hypoxia-driven occurrence of chronic kidney disease and osteoporosis in COPD individuals: New insights into environmental cadmium exposure.

Clinical Profile and Treatment Outcomes of Hypermanganesemia with Dystonia 1 and 2 among 27 Indian Children.

Manganese and related neurotoxic pathways: A potential therapeutic target in neurodegenerative diseases.

Redox stress and metal dys-homeostasis appear as hallmarks of early prion disease pathogenesis in mice.

Enhancement of astrocytic gap junctions Connexin43 coupling can improve long-term isoflurane anesthesia-mediated brain network abnormalities and cognitive impairment.

Pathophysiological studies of aging Slc39a14 knockout mice to assess the progression of manganese-induced dystonia-parkinsonism.

Endosomal recycling defects link Huntington's disease with McLeod syndrome.

Impaired XK recycling for importing manganese underlies striatal vulnerability in Huntington's disease.

Metal Ion Periplasmic-Binding Protein YfeA of Glaesserella parasuis Induces the Secretion of Pro-Inflammatory Cytokines of Macrophages via MAPK and NF-κB Signaling through TLR2 and TLR4.

The schizophrenia-associated missense variant rs13107325 regulates dendritic spine density.

Multivalent Gd-DOTA Decorated Oligopeptide as Sensitive MRI Molecular Probes for In Vivo Imaging of Brain Connectivity.

Empagliflozin improves cardiac mitochondrial function and survival through energy regulation in a murine model of heart failure.

Chronic Fluoxetine Treatment of Socially Isolated Rats Modulates Prefrontal Cortex Proteome.

Interaction between manganese and SLC6A3 genetic polymorphisms in relation to dyslexia.

Lone-Pair-Like Interaction and Bonding Inhomogeneity Induce Ultralow Lattice Thermal Conductivity in Filled β-Manganese-Type Phases.

The mitochondrial RNA granule modulates manganese-dependent cell toxicity.

Metal Homeostasis in Pathogenic Streptococci.

Quantitative Trait Locus Mapping of Marsh Spot Disease Resistance in Cranberry Common Bean (Phaseolus vulgaris L.).

Divalent Metal Uptake and the Role of ZIP8 in Host Defense Against Pathogens.

Axonal Transport Impairment and its Relationship with Diffusion Tensor Imaging Metrics of a Murine Model of p301L Tau Induced Tauopathy.

The Combined Inactivation of Intestinal and Hepatic ZIP14 Exacerbates Manganese Overload in Mice.

Prime Real Estate: Metals, Cofactors and MICOS.

Mitochondrial Cytochrome c Oxidase Defects Alter Cellular Homeostasis of Transition Metals.

Genomic Analyses Identify Manganese Homeostasis as a Driver of Group B Streptococcal Vaginal Colonization.

Deletion of RE1-silencing transcription factor in striatal astrocytes exacerbates manganese-induced neurotoxicity in mice.

Effects of individual amino acid mutations of zinc transporter ZIP8 on manganese- and cadmium-transporting activity.

Involvement of a putative ATP-Binding Cassette (ABC) Involved in manganese transport in virulence of Listeria monocytogenes.

Global transcriptomic analysis of ethanol tolerance response in Salmonella Enteritidis.

Manganese-enhanced magnetic resonance imaging method detects age-related impairments in axonal transport in mice and attenuation of the impairments by a microtubule-stabilizing compound.

Antioxidant Capacity Is Decreased in Wilson's Disease and Correlates to Liver Function.

Loss of slc39a14 causes simultaneous manganese hypersensitivity and deficiency in zebrafish.

Integration of iron-manganese layered double hydroxide/tungsten carbide composite: An electrochemical tool for diphenylamine H•+ analysis in environmental samples.

A rare genetic variant in the manganese transporter SLC30A10 and elevated liver enzymes in the general population.

MnTE-2-PyP protects fibroblast mitochondria from hyperglycemia and radiation exposure.

Effect of Chelation Therapy on a Korean Patient With Brain Manganese Deposition Resulting From a Compound Heterozygous Mutation in the SLC39A14 Gene.

Longitudinal manganese-enhanced magnetic resonance imaging of neural projections and activity.

Neurotoxicity and gene expression alterations in zebrafish larvae in response to manganese exposure.

TdfH selectively binds metal-loaded tetrameric calprotectin for zinc import.

On the Interplay Between Oxygen Vacancies and Small Polarons in Manganese Iron Spinel Oxides.

Golgi Metal Ion Homeostasis in Human Health and Diseases.

"Cock-walk" gait and "horseshoe moustache" sign on MRI in inherited hypermanganesemia.

Adrenomedullin ameliorates palmitic acid-induced insulin resistance through PI3K/Akt pathway in adipocytes.

Systematic and state-of the science review of the role of environmental factors in Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig's Disease.

Manganese transport in mammals by zinc transporter family proteins, ZNT and ZIP.

The association of bone and blood manganese with motor function in Chinese workers.

Alteration of the gut microbiota in rhesus monkey with spontaneous osteoarthritis.

Manganese phosphorylates Yin Yang 1 at serine residues to repress EAAT2 in human H4 astrocytes.

Role of excretion in manganese homeostasis and neurotoxicity: a historical perspective.

The Impact of ZIP8 Disease-Associated Variants G38R, C113S, G204C, and S335T on Selenium and Cadmium Accumulations: The First Characterization.

Astrocytic transcription factor REST upregulates glutamate transporter EAAT2, protecting dopaminergic neurons from manganese-induced excitotoxicity.

Chronic Intestinal Inflammation Suppresses Brain Activity by Inducing Neuroinflammation in Mice.

Alcohol exposure increases manganese accumulation in the brain and exacerbates manganese-induced neurotoxicity in mice.

Trace metals and animal health: Interplay of the gut microbiota with iron, manganese, zinc, and copper.

Titratable transmembrane residues and a hydrophobic plug are essential for manganese import via the Bacillus anthracis ABC transporter MntBC-A.

Revealing the role of Plant Growth Promoting Rhizobacteria in suppressive soils against Fusarium oxysporum f.sp. cubense based on metagenomic analysis.