Bloqueio cardíaco que ocorre antes dos 28 dias de vida.
Introdução
O que você precisa saber de cara
Bloqueio cardíaco que ocorre antes dos 28 dias de vida.
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
1/2k
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Entender a doença
Do básico ao detalhe, leia no seu ritmo
Preparando trilha educativa...
Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Partes do corpo afetadas
+ 19 sintomas em outras categorias
Características mais comuns
Os sintomas variam de pessoa para pessoa. Abaixo estão as 36 características clínicas mais associadas, ordenadas por frequência.
Linha do tempo da pesquisa
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Genética e causas
O que está alterado no DNA e como passa nas famílias
Nenhum gene associado encontrado
Os dados genéticos desta condição ainda estão sendo catalogados.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Bloqueio cardíaco congênito
Centros de Referência SUS
24 centros habilitados pelo SUS para Bloqueio cardíaco congênito
Centros para Bloqueio cardíaco congênito
Detalhes dos centros
Hospital Universitário Prof. Edgard Santos (HUPES)
R. Dr. Augusto Viana, s/n - Canela, Salvador - BA, 40110-060 · CNES 0003808
Serviço de Referência
Hospital Infantil Albert Sabin
R. Tertuliano Sales, 544 - Vila União, Fortaleza - CE, 60410-794 · CNES 2407876
Serviço de Referência
Hospital de Apoio de Brasília (HAB)
AENW 3 Lote A Setor Noroeste - Plano Piloto, Brasília - DF, 70684-831 · CNES 0010456
Serviço de Referência
Hospital Estadual Infantil e Maternidade Alzir Bernardino Alves (HIABA)
Av. Min. Salgado Filho, 918 - Soteco, Vila Velha - ES, 29106-010 · CNES 6631207
Serviço de Referência
Hospital das Clínicas da UFG
Rua 235 QD. 68 Lote Área, Nº 285, s/nº - Setor Leste Universitário, Goiânia - GO, 74605-050 · CNES 2338424
Serviço de Referência
Hospital Universitário da UFJF
R. Catulo Breviglieri, Bairro - s/n - Santa Catarina, Juiz de Fora - MG, 36036-110 · CNES 2297442
Atenção Especializada
Hospital das Clínicas da UFMG
Av. Prof. Alfredo Balena, 110 - Santa Efigênia, Belo Horizonte - MG, 30130-100 · CNES 2280167
Serviço de Referência
Hospital Universitário Julio Müller (HUJM)
R. Luis Philippe Pereira Leite, s/n - Alvorada, Cuiabá - MT, 78048-902 · CNES 2726092
Atenção Especializada
Hospital Universitário João de Barros Barreto
R. dos Mundurucus, 4487 - Guamá, Belém - PA, 66073-000 · CNES 2337878
Serviço de Referência
Hospital Universitário Lauro Wanderley (HULW)
R. Tabeliao Estanislau Eloy, 585 - Castelo Branco, João Pessoa - PB, 58050-585 · CNES 0002470
Atenção Especializada
Instituto de Medicina Integral Prof. Fernando Figueira (IMIP)
R. dos Coelhos, 300 - Boa Vista, Recife - PE, 50070-902 · CNES 0000647
Serviço de Referência
Hospital Pequeno Príncipe
R. Des. Motta, 1070 - Água Verde, Curitiba - PR, 80250-060 · CNES 3143805
Serviço de Referência
Hospital Universitário Regional de Maringá (HUM)
Av. Mandacaru, 1590 - Parque das Laranjeiras, Maringá - PR, 87083-240 · CNES 2216108
Atenção Especializada
Hospital de Clínicas da UFPR
R. Gen. Carneiro, 181 - Alto da Glória, Curitiba - PR, 80060-900 · CNES 2364980
Serviço de Referência
Hospital Universitário Pedro Ernesto (HUPE-UERJ)
Blvd. 28 de Setembro, 77 - Vila Isabel, Rio de Janeiro - RJ, 20551-030 · CNES 2280221
Serviço de Referência
Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira (IFF/Fiocruz)
Av. Rui Barbosa, 716 - Flamengo, Rio de Janeiro - RJ, 22250-020 · CNES 2269988
Serviço de Referência
Hospital São Lucas da PUCRS
Av. Ipiranga, 6690 - Jardim Botânico, Porto Alegre - RS, 90610-000 · CNES 2232928
Serviço de Referência
Hospital de Clínicas de Porto Alegre (HCPA)
Rua Ramiro Barcelos, 2350 Bloco A - Av. Protásio Alves, 211 - Bloco B e C - Santa Cecília, Porto Alegre - RS, 90035-903 · CNES 2237601
Serviço de Referência
Hospital Universitário da UFSC (HU-UFSC)
R. Profa. Maria Flora Pausewang - Trindade, Florianópolis - SC, 88036-800 · CNES 2560356
Serviço de Referência
Hospital das Clínicas da FMUSP
R. Dr. Ovídio Pires de Campos, 225 - Cerqueira César, São Paulo - SP, 05403-010 · CNES 2077485
Serviço de Referência
Hospital de Base de São José do Rio Preto
Av. Brg. Faria Lima, 5544 - Vila Sao Jose, São José do Rio Preto - SP, 15090-000 · CNES 2079798
Atenção Especializada
Hospital de Clínicas da UNICAMP
R. Vital Brasil, 251 - Cidade Universitária, Campinas - SP, 13083-888 · CNES 2748223
Serviço de Referência
Hospital de Clínicas de Ribeirão Preto (HCRP-USP)
R. Ten. Catão Roxo, 3900 - Vila Monte Alegre, Ribeirão Preto - SP, 14015-010 · CNES 2082187
Serviço de Referência
UNIFESP / Hospital São Paulo
R. Napoleão de Barros, 715 - Vila Clementino, São Paulo - SP, 04024-002 · CNES 2688689
Serviço de Referência
Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.
Pesquisa ativa
Ensaios clínicos abertos e novidades científicas recentes
Ensaios em destaque
Pesquisa e ensaios clínicos
8 ensaios clínicos encontrados.
Publicações mais relevantes
Peripartum Cardiogenic Shock From Effusive-Constrictive Pericarditis Requiring VA-ECMO and Pericardiectomy.
Conduction system pacing in a congenital heart block patient with epicardial left ventricular pacing heart failure.
Role of Hydroxychloroquine in Prevention of Congenital Heart Block in Pregnant Women With Positive Anti-Ro/SSA and/or Anti-La/SSB.
Neonatal lupus, a condition primarily affecting infants born to mothers with anti-Ro/SSA and/or anti-La/SSB antibodies, is linked to congenital heart block (CHB), a potentially life-threatening complication. Hydroxychloroquine (HCQ), an antimalarial with immunomodulatory properties, has been shown to reduce CHB recurrence. This review examines current evidence on HCQ's role in preventing CHB in pregnancies affected by those autoantibodies, focusing on overall, primary and secondary prevention. Evidence supports HCQ in overall and secondary prevention, but data on its effectiveness for primary prevention is lacking. Clinical guidelines, antibody titre thresholds, foetal heart rate monitoring and the need for randomised controlled trials are discussed.
Skin-Limited Neonatal Lupus in an Infant Conceived by In Vitro Fertilization and Surrogate Gestation.
Neonatal lupus erythematosus (NLE) is a rare autoimmune condition caused by the transplacental passage of maternal anti-Ro/SSA and anti-La/SSB antibodies, typically presenting with annular erythema or congenital heart block. We report a 3-month-old infant conceived by in vitro fertilization and carried by a surrogate mother who developed annular erythematous plaques in typical and atypical locations at 1 month of age. Skin biopsy and serologic testing confirmed NLE despite the absence of a known maternal autoimmune history; maternal anti-Ro/SSA and anti-La/SSB positivity was identified retrospectively through the surrogate's obstetrician. The cutaneous findings improved significantly with photoprotection and resolved without systemic involvement.
Systemic Manifestations of Neonatal Lupus in an Infant Born to an Asymptomatic Mother: A Case Report of Anemia and Transaminitis.
BACKGROUND Neonatal lupus erythematosus (NLE) is a rare autoimmune disorder caused by the transplacental transfer of maternal autoantibodies, primarily anti-Ro/SSA and anti-La/SSB. Common clinical manifestations include cutaneous lesions and congenital heart block; however, systemic involvement such as anemia and transaminitis remains infrequently reported, particularly in Southeast Asian populations. Diagnosis is often missed, especially in infants born to asymptomatic mothers. CASE REPORT A 1-month-old full-term female infant born via cesarean section presented with annular erythematous skin lesions since birth, distributed across the face, chest, and extremities. Laboratory tests revealed normocytic normochromic anemia, thrombocytopenia, and elevated aspartate aminotransferase/alanine aminotransferase levels. Although the electrocardiogram was normal, echocardiography showed a secundum-type atrial septal defect and mild tricuspid regurgitation. Skin biopsy revealed histopathological features consistent with cutaneous lupus. Both maternal and infant serology were positive for anti-Ro and anti-La antibodies. A diagnosis of cutaneous NLE with systemic manifestations was established. Prednisone therapy at a dose of 0.5 mg/kg/day was initiated, along with education on how to avoid sun exposure. After 2 months of therapy, the skin lesions had resolved, and laboratory parameters had improved. CONCLUSIONS This case highlights the importance of considering NLE as a differential diagnosis in infants presenting with cutaneous lesions and systemic abnormalities, even when the mother is asymptomatic. Early diagnosis and appropriate treatment can prevent complications and support optimal clinical recovery.
Publicações recentes
The Prevalence of Fetal Complete Heart Block and the Role of Positive Autoantibodies in Pregnant Women with Rheumatologic Diseases.
Maternal and fetal outcomes in pregnancies affected by mixed connective tissue disease.
Prenatal Diagnosis of Immune-Mediated Fetal Complete Heart Block Revealing Maternal Systemic Lupus Erythematosus.
Role of Hydroxychloroquine in Prevention of Congenital Heart Block in Pregnant Women With Positive Anti-Ro/SSA and/or Anti-La/SSB.
Skin-Limited Neonatal Lupus in an Infant Conceived by In Vitro Fertilization and Surrogate Gestation.
📚 EuropePMC430 artigos no totalmostrando 194
Role of Hydroxychloroquine in Prevention of Congenital Heart Block in Pregnant Women With Positive Anti-Ro/SSA and/or Anti-La/SSB.
The Australian & New Zealand journal of obstetrics & gynaecologySkin-Limited Neonatal Lupus in an Infant Conceived by In Vitro Fertilization and Surrogate Gestation.
Pediatric dermatologySystemic Manifestations of Neonatal Lupus in an Infant Born to an Asymptomatic Mother: A Case Report of Anemia and Transaminitis.
The American journal of case reportsAssociation between maternal anti-Ro and anti-La antibody levels and congenital heart block: a 20-year cohort study.
Archives of gynecology and obstetricsPeripartum Cardiogenic Shock From Effusive-Constrictive Pericarditis Requiring VA-ECMO and Pericardiectomy.
Circulation. Heart failureConduction system pacing in a congenital heart block patient with epicardial left ventricular pacing heart failure.
European heart journal. Case reportsFetal echocardiographic surveillance in anti-SSA/Ro-SSB/La-Positive systemic lupus erythematosus pregnancies: risk stratification of congenital heart block.
Rheumatology (Oxford, England)Case Report: A multidisciplinary, protocol-driven pathway from recurrent pregnancy loss to live birth in an anti-Ro/SSA-positive primary Sjögren's syndrome pregnancy with literature review.
Frontiers in immunologyHeart Block in Pregnancy From Parvovirus B19.
JACC. Case reportsPrediction of foetal atrioventricular conduction using maternal disease, treatment and anti-Ro/La autoantibody levels.
Rheumatology (Oxford, England)Atrioventricular block in the newborn period.
HeartRhythm case reportsCase Report: The case of atypical OAPS complicated by positive anti-SSA and anti-SSB antibodies.
Frontiers in immunologyCurrent and future interventions for neonatal lupus: A review of the national library of Medicine's clinical trials database.
LupusHydroxychloroquine After Complete Heart Block Diagnosis and Relationship to Patient Outcomes: A Descriptive Cohort Study.
Prenatal diagnosisMaternal Primary Sjögren's Syndrome Complicated by Irreversible Fetal Third-Degree Congenital Heart Block: A Case Report From Nepal.
Clinical case reportsA Multi-Institutional Case Series of Neonatal Lupus Erythematosus Without Cardiac Involvement From Vietnam.
Case reports in pediatricsHeartbeat of hope: newborn's journey with a pacemaker.
BMJ case reportsAutoimmune antibodies in arrhythmia: a narrative review of potential therapeutic targets to prevent overtreatment.
Cardiovascular diagnosis and therapyHydroxychloroquine in systemic lupus erythematosus, anti-SSA/SSB, and antiphospholipid antibody-positive pregnancies.
American journal of obstetrics and gynecologyFetal and maternal adverse cardiac outcomes in rheumatic diseases: A systematic review.
European journal of obstetrics, gynecology, and reproductive biologyAssessment of fetal left ventricular function in pregnancies with Anti-Ro/SSA or Anti-La/SSB antibodies using velocity vector imaging.
BMC pregnancy and childbirthFlail Tricuspid and Mitral Valve in Neonatal Lupus.
JACC. Case reportsSafety and Feasibility of Implanting Dual-Chamber Permanent Pacemakers in Patients Under 3 kg.
World journal for pediatric & congenital heart surgeryPregnancy Outcomes in Women With Systemic Lupus Erythematosus (SLE): A Matched-Observational Study From India.
International journal of rheumatic diseasesEffects of maternal anti-Ro/La antibodies on fetal atrioventricular conduction evaluated with echocardiography: a state-of-the-art review.
Archives of gynecology and obstetricsCongenital Complete Heart Block Requiring Temporary Pacemaker Placement at Birth: A Case Report.
Seminars in cardiothoracic and vascular anesthesiaPrevention and treatment of autoimmune-mediated congenital heart block: practice provider survey from UK cardiac centres.
Archives of disease in childhood. Fetal and neonatal editionOne step closer to predicting autoimmune congenital heart block?
The Lancet. RheumatologyMaternal autoantibodies to the sodium potassium pump α1 subunit AT1A1 and fetal autoimmune congenital heart block: a case-control study.
The Lancet. RheumatologyNeonatal Lupus Erythematosus With Congenital Heart Block.
Journal of cutaneous medicine and surgeryAdverse Pregnancy Outcomes in Sjogren's Disease Compared to Controls: An Interdisciplinary Approach with Maternal-Fetal Medicine.
AJP reportsClinical characteristics of neonatal lupus erythematosus complicated by congenital heart block: a multi-center retrospective study in East China.
Scientific reportsNeonatal lupus erythematosus presenting with congenital heart block: clinical characteristics and follow-up.
Clinical rheumatologyA 1-year review of anti-Ro/La autoantibody testing in an obstetric population.
Irish journal of medical scienceWhen should a neonatologist consult a rheumatologist?
European journal of pediatricsNeonatal lupus erythematosus: an acquired autoimmune disease to be taken seriously.
Annals of medicineImmune and non-immune congenital heart block: a tale of two very different entities.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of CardiologyDual- vs Single-Chamber Ventricular Pacing in Isolated Congenital Complete Atrioventricular Block in Infancy.
JACC. Clinical electrophysiologyTreatment options for preventing autoimmune-mediated congenital heart block: a systematic review.
Archives of disease in childhoodSpontaneous conversion of fetal heart block to sinus rhythm post externalized pacemaker placement in an undiagnosed mother with lupus antibodies.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal ObstetriciansMaternal autoimmune systemic connective tissue disease and vasculitis and electrocardiographic findings in the offspring.
Journal of autoimmunityMyocardial perfusion imaging in a case of cardiac strangulation: A novel approach to detect pacemaker-induced ischemia.
Annals of pediatric cardiologyConstrictive pericarditis following epicardial pacemaker implant: a diagnostic dilemma.
Cardiology in the youngDual Chamber Aveir Retrievable Leadless Pacemaker Implant via the Right Internal Jugular Vein in a 13-Year-Old With Congenital Complete Heart Block.
Pacing and clinical electrophysiology : PACENeonatal lupus erythematosus: 24 years of experience from a tertiary centre at Chandigarh, North India.
LupusSubxiphoid Insertion of a Pediatric Implantable Pulse Generator in a Neonate With Congenital Complete Heart Block.
World journal for pediatric & congenital heart surgeryNeonatal lupus erythematosus successfully treated by exchange transfusion: a case report and literature review.
Frontiers in pediatricsImpact of early detection and steroid treatment on fetal ventricular heart rate and pacemaker implantation in anti-Ro/SSA positive congenital heart block.
Acta obstetricia et gynecologica Scandinavica"An update on the approach to treatment of Sjogren's Disease in pregnancy".
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal ObstetriciansFetal and Maternal Outcomes in a Cohort of Patients With Primary Sjogren's Syndrome: An Observational Study.
CureusReview of Systemic Lupus Erythematous-Reply.
JAMAReview of Systemic Lupus Erythematous.
JAMADual challenge inside the womb: a case report of concomitant fetal atrio-ventricular block associated with maternal anti-SSA antibodies and fetal tachyarrhythmia diagnosed as Wolff-Parkinson-White syndrome after birth.
Frontiers in immunologySjogren's Antibodies and Neonatal Lupus: A Scoping Review.
CureusDysregulation of immune checkpoint molecules as a characteristic of autoimmune congenital heart block.
Annals of the rheumatic diseasesComplete Congenital Heart Block in the Offspring of an Asymptomatic Woman with Isolated High Titer Anti-Ro Antibody.
Acta medica PhilippinaCongenital Complete Heart Block-To Stimulate (When?) or Not to Stimulate?
Healthcare (Basel, Switzerland)Complex Presentation of Congenital Heart Block and Coexisting Congenital Heart Disease in a One-Year-Old Girl: A Case Report.
CureusMolecular Mechanisms of Fetal and Neonatal Lupus: A Narrative Review of an Autoimmune Disease Transferal across the Placenta.
International journal of molecular sciencesComparing pregnancy outcomes in patients with Systemic Lupus Erythematosus (SLE) and Undifferentiated Connective Tissue Disease (UCTD): a descriptive cohort study.
Revista clinica espanolaManagement of pregnancy in autoimmune rheumatic diseases: maternal disease course, gestational and neonatal outcomes and use of medications in the prospectiveItalian P-RHEUM.it study.
RMD openIsolated non-immune-mediated second-degree atrioventricular block in the fetus: natural history and predictive factors for spontaneous recovery.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and GynecologyHome monitoring of fetal heart rhythm: Lived experiences of women with anti-SSA/Ro52 autoantibodies and their co-parents.
LupusSubclinical maternal autoimmune disease leading to congenital high degree atrioventricular block: Case report and review of the literature.
Cardiovascular pathology : the official journal of the Society for Cardiovascular PathologyPrevalence of neonatal lupus in a small group of antibody-carrying mothers and frequency of complete atrioventricular block.
Archivos de cardiologia de MexicoLate-Onset Dilated Cardiomyopathy in Auto Immune-Mediated Complete Congenital Heart Block: A Case Report.
CureusCritical congenital heart disease: contemporary prenatal screening performance and outcomes in a multi-centre perinatology service.
BMC pregnancy and childbirthNewborns with congenital complete heart block: Advice for perinatal care providers.
Tropical doctorA novel miniaturized adult pacemaker system for small neonates with congenital heart block.
JTCVS techniquesAutoimmune congenital heart block: a case report and review of the literature related to pathogenesis and pregnancy management.
Arthritis research & therapy[Clinical characteristics of fetal cardiac disease in patients with anti-SSA antibody positive].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciencesPregnancy and Inflammatory Rheumatological Diseases: A Single-Center Retrospective Cohort Study.
CureusExperience of treating congenital complete atrioventricular block with epicardial pacemaker in infants and young children: a retrospective study.
BMC cardiovascular disordersLongitudinal echocardiographic parameters before and after pacemaker placement in congenital complete heart block.
Heart rhythmExpert Perspective on a Clinical Challenge: Lupus and Pregnancy.
Arthritis & rheumatology (Hoboken, N.J.)Reverse complete heart block using transcutaneous pacing and repeated plasmapheresis in a neonate with lupus: a case report.
Pediatric rheumatology online journalPerivascular Basal Echogenicity in the Fetal Heart: An Unconventional Marker of Maternal Autoimmune Antibodies.
Pediatric cardiologyEpicardial pacing lead implantation for congenital complete atrioventricular block immediately after birth: a case report.
Journal of medical case reportsCongenital Heart Block and Its Association With Anti-Ro and Anti-La Antibodies in Pregnancy: A Case Report of a Rare Entity and a Review of the Current Evidence.
CureusPregnancy Outcomes in Patients with Primary Sjögren's Syndrome Undergoing Assisted Reproductive Therapy: A Multi-center Retrospective Study.
Rheumatology and therapyNeonatal lupus erythematosus manifested as a complete heart block: A case report.
Clinical case reportsThe role of cardiac anaesthesiologists in placing a temporary transvenous endocardial lead in the operation room during pulse generator replacement in a child with congenital complete heart block.
Annals of cardiac anaesthesiaReversible complete atrioventricular block in a neonate with maternal anti-Sjögren's syndrome-associated antibody: atypical phenotype of autoimmune congenital heart block.
Cardiology in the youngPercutaneous extraction of a protruding atrial pacing lead in an 8-year-old child.
Journal of cardiology casesPlacement of permanent pacemaker in a low-birth-weight infant with congenital heart block: a case report.
JPMA. The Journal of the Pakistan Medical AssociationCase report: Challenges and implications of conduction system pacing in pediatrics: Case series.
Frontiers in pediatricsAutoimmune Congenital Complete Heart Block: How Late Can It Occur?
AJP reportsEmergency pacing via the umbilical vein of a neonate with congenital complete atrioventricular block: a report of two cases.
Cardiology in the youngContribution of S100A4-expressing fibroblasts to anti-SSA/Ro-associated atrioventricular nodal calcification and soluble S100A4 as a biomarker of clinical severity.
Frontiers in immunologyIdentifying Congenital Heart Block in Primary Care.
Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & PractitionersMaternal and infant outcomes of pregnancy associated with anti-SSA/RO antibodies: a systematic review and meta-analysis.
Pediatric rheumatology online journalPediatric Epicardial Devices: Early and Midterm Outcomes.
World journal for pediatric & congenital heart surgeryNeonatal lupus erythematosus - prevention is better than cure.
Postepy dermatologii i alergologiiVentricular Functional Analysis in Congenital Complete Heart Block Using Speckle Tracking: Left Ventricular Epicardial Compared to Right Ventricular Septal Pacing.
Pediatric cardiologySuccessful Pregnancy with SLE-associated Antiphospholipid Syndrome: A Case Report.
Mymensingh medical journal : MMJA Case of Neonatal Lupus Presenting with Myocardial Dysfunction in the Absence of Congenital Heart Block (CHB): Clinical Management and Brief Literature Review of Neonatal Cardiac Lupus.
Pediatric cardiologySjögren's syndrome and pregnancy: a Portuguese case-control study.
ReumatologiaAnti-SSA/Ro positivity and congenital heart block: obstetric and foetal outcome in a cohort of anti-SSA/Ro positive pregnant patients with and without autoimmune diseases.
Clinical and experimental rheumatologyNeonatal Lupus presenting with neonatal hemochromatosis-like liver disease that responded to steroids: a case report.
BMC pediatricsmiR Profile of Chronic Right Ventricular Pacing: a Pilot Study in Children with Congenital Complete Atrioventricular Block.
Journal of cardiovascular translational researchFetal Arrhythmia Diagnosis and Pharmacologic Management.
Journal of clinical pharmacologyFavourable outcome of a severe bradyarrhythmia in a neonate: a case report.
Cardiology in the youngShort and long-term outcomes of children with autoimmune congenital heart block treated with a combined maternal-neonatal therapy. A comparison study.
Journal of perinatology : official journal of the California Perinatal AssociationConduction System Pacing in Pediatrics and Congenital Heart Disease, a Single Center Series of 24 Patients.
Pediatric cardiologyHealth Outcomes of 215 Mothers of Children With Autoimmune Congenital Heart Block: Analysis of the French Neonatal Lupus Syndrome Registry.
The Journal of rheumatologyPregnancy outcomes of a joint obstetric and rheumatology clinic in a tertiary centre: a 2-year retrospective study of 98 pregnancies.
Rheumatology advances in practiceAuxilin is a novel susceptibility gene for congenital heart block which directly impacts fetal heart function.
Annals of the rheumatic diseasesHistological finding of maternal antibody-associated congenital heart block accompanied by large atrial septal defect and severe cardiac dysfunction.
Cardiology in the youngSuccess with caution: Forty years of congenital complete atrioventricular block.
Heart rhythmTransvenous laser lead extraction in patients with congenital complete heart block.
Heart rhythmHis Bundle pacing for congenital complete AV block: An attempt to fix a broken heart?
Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, IncIncidence of morbidity and mortality in a cohort of congenital complete heart block patients followed over 40 years.
Heart rhythmAnti-Ro52 Autoantibody Is Common in Systemic Autoimmune Rheumatic Diseases and Correlating with Worse Outcome when Associated with interstitial lung disease in Systemic Sclerosis and Autoimmune Myositis.
Clinical reviews in allergy & immunologyNAFTNet retrospective report on the treatment of anti-Ro/SSA mediated fetal heart block with dexamethasone.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal ObstetriciansPrenatal predisposing factors associated with neonatal lupus erythematosus.
Lupus[Detection and prevention of maternal autoantibody-related congenital heart block].
Zhonghua xin xue guan bing za zhiSystemic erythematosus lupus and pregnancy outcomes in a Colombian cohort.
LupusComplete heart block in neonatal lupus: a forgotten cause of fetal bradycardia.
BMJ case reportsCohort study of congenital complete heart block among preterm neonates: a single-center experience over a 15-year period.
European journal of pediatricsSystemic lupus erythematosus and pregnancy: A retrospective single-center study of 215 pregnancies from Portugal.
LupusFetal Congenital Heart Block Associated With Maternal Primary Systemic Lupus Erythematosus and Sjogren's Syndrome.
CureusThird Trimester Fetal Heart Rates in Antibody-Mediated Complete Heart Block Predict Need for Neonatal Pacemaker Placement.
Pediatric cardiologyClinical utility of fetal echocardiography: an Egyptian center experience.
The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of CardiologyVentricular pacing and myocardial function in patient with congenital heart block.
Journal of cardiovascular electrophysiologyVentricular pacing and myocardial function in patients with congenital heart block: Is it time to consider de novo biventricular pacing?
Journal of cardiovascular electrophysiologyLow prevalence of anti-SSA (anti-Ro) and anti-SSB (anti-La) autoantibodies in female patients with rheumatoid arthritis with a wish to conceive.
RMD openEarly-Onset Cardiomyopathy After Pacemaker Implanted in a Preterm Infant With Congenital Complete Heart Block and Anti-Ro/SSA Antibodies.
Texas Heart Institute journalPrenatal Management Strategy for Immune-Associated Congenital Heart Block in Fetuses.
Frontiers in cardiovascular medicineHis Bundle Pacing in Congenital Complete Heart Block: Making HIStory?
JACC. Clinical electrophysiologyTemporary pacemaker implantation through umbilical vein in a low birth weight neonate with congenital complete heart block.
Cardiology in the youngEthnicity and Neonatal Lupus Erythematosus Manifestations Risk in a Large Multiethnic Cohort.
The Journal of rheumatologySuccessful 2-Stage Pacemaker Implantation for Atrioventricular Block in a Low-Birth-Weight Infant with Congenital Heart Disease: Case Report.
The heart surgery forumCase series of late lead dislodgement of Medtronic SelectSecure 3830 pacing leads in growing paediatric patients.
European heart journal. Case reportsSuccessful perinatal management and pacemaker stimulation during the first hour of life in a 1.6 kg newborn with autoimmune congenital complete heart block diagnosed prenatally.
Ginekologia polskaFirst trimester combined screening test for aneuploidies in anti-Ro carriers pregnant women.
Clinical rheumatologyHome fetal heart rate monitoring in anti Ro/SSA positive pregnancies: Literature review and case report.
European journal of obstetrics, gynecology, and reproductive biologyBosentan-induced immune hemolytic anemia in 17 years old man. A case report.
Daru : journal of Faculty of Pharmacy, Tehran University of Medical SciencesNeonatal lupus erythematosus - practical guidelines.
Journal of perinatal medicineMaternal and Fetal Outcomes in Systemic Lupus Erythematosus Pregnancies.
Annals of the Academy of Medicine, SingaporeAutoimmune Congenital Heart Block: A Review of Biomarkers and Management of Pregnancy.
Frontiers in pediatricsPermanent His Bundle Pacing in Patients With Congenital Complete Heart Block: A Multicenter Experience.
JACC. Clinical electrophysiologyLongitudinal Analysis of Fetal Ventricular Rate for Risk Stratification in Immune Congenital Heart Block.
Fetal diagnosis and therapyFalse Asystole Alarms Post-Temporary Pacemaker Placement Due to Pseudo-fusion.
Pediatric cardiologyLong-term physical and neurodevelopmental outcomes after antenatal betamethasone administration for congenital heart block prevention.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal ObstetriciansPulmonary hypertension associated with congenital heart block and neonatal lupus syndrome: A series of four cases.
LupusInterferons and innate immune activation in autoimmune congenital heart block.
Scandinavian journal of immunologyElective Inguinal Hernia Surgery in the Setting of Unfollowed Congenital Complete Heart Block With No Postponement.
CureusUmbilical and Middle Cerebral Artery Doppler Measurements in Fetuses With Congenital Heart Block.
Journal of the American Society of Echocardiography : official publication of the American Society of EchocardiographyClinical Features, Autoantibodies, and Outcome of Neonatal Lupus Erythematosus.
Fetal and pediatric pathologyA novel technique for extraction of a leadless pacemaker that embolized to the pulmonary artery in a young patient: A case report.
HeartRhythm case reportsAutoimmune congenital heart block and primary Sjögren's syndrome: characterisation and outcomes of 49 cases.
Clinical and experimental rheumatologyNatural killer cells and type II interferon in Ro/SSA and La/SSB autoantibody-exposed newborns at risk of congenital heart block.
Annals of the rheumatic diseasesMortality in congenital heart block - Authors' reply.
The Lancet. RheumatologyMortality in congenital heart block.
The Lancet. RheumatologyPrimary Sjögren's syndrome in South Australia.
Clinical and experimental rheumatologyElectrocardiographic QT Intervals in Infants Exposed to Hydroxychloroquine Throughout Gestation.
Circulation. Arrhythmia and electrophysiologyDiagnosis and Management of Fetal Autoimmune Atrioventricular Block.
International journal of women's healthThe importance of lead management in the young paced patient. The case of a 22-year-old female with congenital complete heart block.
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheoreseCongenital complete heart block in the setting of severe pre-eclampsia requiring urgent cesarean section.
International journal of obstetric anesthesiaCongenital Heart Block in Subsequent Pregnancies of SSA/Ro-Positive Mothers: Cutting Recurrence in Half.
Journal of the American College of CardiologyHydroxychloroquine to Prevent Recurrent Congenital Heart Block in Fetuses of Anti-SSA/Ro-Positive Mothers.
Journal of the American College of CardiologyA Broader Perspective on Anti-Ro Antibodies and Their Fetal Consequences-A Case Report and Literature Review.
Diagnostics (Basel, Switzerland)Treatment and follow-up of fetuses that developed congenital heart block due to autoantibody in two cases.
The Journal of international medical researchFluorinated steroids are not superior to any treatment to ameliorate the outcome of autoimmune mediated congenital heart block: a systematic review of the literature and meta-analysis.
Clinical and experimental rheumatologyA missense mutation of ErbB2 produces a novel mouse model of stillbirth associated with a cardiac abnormality but lacking abnormalities of placental structure.
PloS oneCommentary: First Report of the Italian Registry on Immune-Mediated Congenital Heart Block (Lu.Ne Registry).
Frontiers in cardiovascular medicineCongenital Complete Atrioventricular Heart Block in a Pregnant Woman with Sjögren Syndrome: Prenatal Care Follow-Up and the Challenge of Intrauterine Treatment.
Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e ObstetriciaLeft ventricular (LV) pacing in newborns and infants: Echo assessment of LV systolic function and synchrony at 5-year follow-up.
Pacing and clinical electrophysiology : PACESurveillance of congenital heart block in highly specialised care - Authors' reply.
The Lancet. RheumatologySurveillance of congenital heart block in highly specialised care.
The Lancet. RheumatologyPermanent left bundle branch pacing: What is the mechanism of divergent responses during programmed stimulation?
Journal of cardiovascular electrophysiologyUmbilical artery catheter, aortic dissection, carotid cannulation, and pseudoaneurysm in a neonate: A tale of propagating pathology.
Annals of pediatric cardiologyType I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero.
RMD openA multicentre study of 244 pregnancies in undifferentiated connective tissue disease: maternal/fetal outcomes and disease evolution.
Rheumatology (Oxford, England)Geoepidemiology and clinical characteristics of neonatal lupus erythematosus: a systematic literature review of individual patients’ data.
Turkish journal of medical sciencesArrhythmia and/or Cardiomyopathy Related to Maternal Autoantibodies: Descriptive Analysis of a Series of 16 Cases From a Single Center.
Frontiers in pediatricsPregnancy control in patients with systemic lupus erythematosus/antiphospholipid syndrome. Part 2: Pregnancy follow-up.
Reumatologia clinicaLong-term Follow-up of Epicardial Pacing and Left Ventricular Dysfunction in Children With Congenital Heart Block.
The Annals of thoracic surgeryAutoimmune-mediated congenital heart block.
Best practice & research. Clinical obstetrics & gynaecologyPregnancy and Systemic Lupus Erythematosus.
Best practice & research. Clinical obstetrics & gynaecologyRoutine repeated echocardiographic monitoring of fetuses exposed to maternal anti-SSA antibodies: time to question the dogma.
The Lancet. RheumatologyCell atlas of the foetal human heart and implications for autoimmune-mediated congenital heart block.
Cardiovascular researchTherapeutic apheresis during pregnancy: A single center experience.
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for HaemapheresisUse of antenatal fluorinated corticosteroids in management of congenital heart block: Systematic review and meta-analysis.
European journal of obstetrics & gynecology and reproductive biology: X[Cardiac Strangulation Induced by Epicardial Pacemaker Leads Causing Heart Failure;Report of a Case].
Kyobu geka. The Japanese journal of thoracic surgeryMinimally invasive technique of placing a dual chamber permanent pacemaker in children.
JPMA. The Journal of the Pakistan Medical AssociationAetiologies and temporal trends of atrioventricular block in young patients: a 20-year nationwide study.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of CardiologyCesarean delivery in congenital heart block and need of temporary pacing: A case report.
Saudi journal of anaesthesiaKeeping upbeat to prevent the heartbreak of anti-Ro/SSA pregnancy.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and GynecologyEffects of maternal medication on long-term outcome in congenital heart block remain to be established. Response to: 'Comorbidity and long-term outcome in patients with congenital heart block and their siblings exposed to Ro/SSA autoantibodies in utero' by Satis et al.
Annals of the rheumatic diseasesCongenital heart block: Pace earlier (Childhood) than later (Adulthood).
Trends in cardiovascular medicineUnconventional 2:1 Ventricular Pacing in a Neonate with Congenital Heart Block and Biventricular Noncompaction.
Texas Heart Institute journalComorbidity and long-term outcome in patients with congenital heart block and their siblings exposed to Ro/SSA autoantibodies in utero.
Annals of the rheumatic diseasesPregnancy outcomes in mixed connective tissue disease: a multicentre study.
Rheumatology (Oxford, England)Associações
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Peripartum Cardiogenic Shock From Effusive-Constrictive Pericarditis Requiring VA-ECMO and Pericardiectomy.
- Conduction system pacing in a congenital heart block patient with epicardial left ventricular pacing heart failure.
- Role of Hydroxychloroquine in Prevention of Congenital Heart Block in Pregnant Women With Positive Anti-Ro/SSA and/or Anti-La/SSB.The Australian & New Zealand journal of obstetrics & gynaecology· 2026· PMID 41879307mais citado
- Skin-Limited Neonatal Lupus in an Infant Conceived by In Vitro Fertilization and Surrogate Gestation.
- Systemic Manifestations of Neonatal Lupus in an Infant Born to an Asymptomatic Mother: A Case Report of Anemia and Transaminitis.
- The Prevalence of Fetal Complete Heart Block and the Role of Positive Autoantibodies in Pregnant Women with Rheumatologic Diseases.
- Maternal and fetal outcomes in pregnancies affected by mixed connective tissue disease.
- Prenatal Diagnosis of Immune-Mediated Fetal Complete Heart Block Revealing Maternal Systemic Lupus Erythematosus.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:60041(Orphanet)
- OMIM OMIM:234700(OMIM)
- MONDO:0009326(MONDO)
- GARD:6164(GARD (NIH))
- Busca completa no PubMed(PubMed)
- Q18558252(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
