Calcifilaxia

Calciphylaxis in Patients With Chronic Kidney Disease - A Study of the Danish Calciphylaxis Research Initiative (DanCaRI)

NCT07511283

Human Amniotic-Derived Mesenchymal Stem Cell Therapy for Calciphylaxis

NCT04592640

Better Evidence and Translation for Calciphylaxis

NCT05018221

A Real-World Registry of Chronic Wounds and Ulcers

NCT02280733

Partners Calciphylaxis Biobank

NCT03032835

NCT07511283 · Calciphylaxis in Patients With Chronic Kidney Disease - A St…Recrutando

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NCT04592640 · Human Amniotic-Derived Mesenchymal Stem Cell Therapy for Cal…Recrutando

EARLY_PHASE1

NCT05018221 · Better Evidence and Translation for CalciphylaxisRecrutando

NCT02280733 · A Real-World Registry of Chronic Wounds and UlcersRecrutando

NCT03032835 · Partners Calciphylaxis BiobankRecrutando

NCT06065852 · National Registry of Rare Kidney DiseasesRecrutando

Outros ensaios clínicos

21 ensaios clínicos encontrados, 7 ativos.

Distribuição por fase

NCT07240649 · Outcomes From Hyperbaric Oxygen (HBO2) Treatment for Emergin…Em breve

PHASE4

NCT02527213 · Double-blind Trial of Sodium Thiosulfate for the Treatment o…Cancelado

NCT06283589 · The SEAPORT 1 Study: Evaluation of the Safety and Tolerabili…Concluído

PHASE1

NCT04195906 · Phase 3 Study of SNF472 for CalciphylaxisConcluído

NCT05633121 · Retrospective Study Evaluating the Contribution of Rheophere…Concluído

NCT02854046 · Calciphylaxis : Population, Risk Factors, Diagnostic Practic…Concluído

NCT01578382 · Pathophysiology of Martorell Hypertensive Ischemic Leg Ulcer…Concluído

NCT03150420 · A Phase 3 Clinical Trial of Intravenous Sodium Thiosulfate i…Encerrado

NCT02278692 · Evaluation of Vitamin K Supplementation for Calcific Uremic …Concluído

NA

NCT02790073 · Phase 2 Study With SNF472 in Calciphylaxis PatientsConcluído

PHASE2

NCT03319914 · Observational Follow-up to ST-001 Calciphylaxis Pain Treatme…Encerrado

NCT03146793 · The Early Administration of Sodium Thiosulfate Should Help t…UNKNOWN

NCT02635373 · European Calciphylaxis Registry NetworkUNKNOWN

NCT01289626 · Efficacy of Lanthanum Carbonate in CalciphylaxisConcluído

PHASE1

Ver todos no ClinicalTrials.gov

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Publicações mais relevantes

Timeline de publicações

874 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 874

#1

Resolution of penile calciphylaxis in a high-risk dialysis patient with medical therapy and wound care.

BMJ case reports2026 Feb 05

Penile calciphylaxis is a rare but life-threatening manifestation of calcific uraemic arteriolopathy, most often seen in patients with end-stage renal disease (ESRD) on dialysis. Its diagnosis is frequently delayed, and its presence carries a poor overall prognosis. Given its rarity, treatment strategies and their efficacy have been understudied and may include observation, medical therapy, radical surgery or hyperbaric oxygen therapy. In this case, we describe a patient with ESRD presenting with a rapidly progressive penile lesion ultimately diagnosed as penile calciphylaxis. Our patient was ineligible for hyperbaric oxygen therapy and declined surgical management. Consequently, unlike many reported cases requiring surgical management nonetheless resulting in poor outcomes, our patient experienced lesional resolution with conservative therapy, specifically intravenous sodium thiosulfate and structured wound care with medical-grade honey, within 9 months after presentation. This case highlights a novel non-surgical approach to a difficult clinical situation and shows the potential efficacy and novelty of non-surgical management in select patients where penile calciphylaxis is diagnosed early in its course.

#2

Lived experiences of patients with calciphylaxis (CALCI-E): a qualitative study.

Journal of nephrology2026 Mar 16

Calciphylaxis is a rare, severe condition, mainly affecting people undergoing dialysis. It occurs when small arterioles within the skin become calcified causing painful skin lesions. There are currently no diagnostic tests or licensed treatments. This qualitative study explored patient experiences to identify opportunities to improve diagnosis and management of this challenging condition. Participants were recruited between October 2023 and December 2024. A sample of 10-20 people was sought. Participants were eligible to take part if they lived in England or Wales and were over 18 years of age, had capacity to consent, and had a current or previous (<3 years) diagnosis of calciphylaxis, or were a caregiver (or relative) of someone with calciphylaxis. Interviews were recorded, transcribed and anonymised, and analysed using inductive, reflexive thematic analysis. Seventeen participants were recruited (14 patients, median age 68 years, 43% male; 3 relatives). Six overarching themes were identified. 1 Diagnostic Delays and Awareness Gaps; symptoms were often dismissed; 2 Pain and Symptom Experience; pain was frequently poorly managed; 3 Treatment and Medication Burden; severe side effects and very limited treatment explanation; 4 Wound Care Variability; often negative experiences and inconsistent practices; 5 Support and Psychological Impact; lack of emotional and practical support; 6 Patient Recommendations; better communication, education, and knowledge sharing. This first in-depth thematic analysis of the experiences of patients who developed calciphylaxis identified key priorities: improved patient/clinician education, better pain and wound management, and enhanced psychosocial and peer support. These findings should inform clinical pathways, educational tools, and support services, with further co-produced research to assess their impact. The study highlights the value of the patients' voices, their willingness to engage, and the need for patient experience measures in calciphylaxis and other rare diseases.

#3

[Challenges of ongoing VKA use in calciphylaxis: The potential of multimodal treatment including rheopheresis, — a case report].

Nephrologie & therapeutique2026 Mar 10

We report two cases of complete remission of uremic calciphylaxis in hemodialysis patients despite continued use of vitamin K antagonists (VKAs). These cases highlight the potential of a multimodal treatment approach including rheopheresis as a promising therapy when VKA discontinuation is not feasible. Both patients presented with severe calciphylaxis while on VKAs for mechanical mitral valve replacement. They received intensive multimodal treatment, including daily hemodialysis, intravenous sodium thiosulfate, calcimimetics, phosphate binders, opioid analgesics, and plastic surgery evaluation. In addition, rheopheresis was initiated twice weekly for four months, during which VKAs were maintained. Rheopheresis frequency was then gradually reduced. Complete wound healing was achieved within seven months. Both patients subsequently underwent parathyroidectomy for tertiary hyperparathyroidism. To our knowledge, these are the first reported cases of full remission of calciphylaxis without VKA discontinuation. A multimodal, multidisciplinary treatment strategy may represent an effective approach for high-risk anticoagulated patients. Nous rapportons deux cas de rémission complète de calciphylaxie urémique chez des patients hémodialysés chroniques, malgré la poursuite d’un traitement par antivitamines K (AVK). Ces cas soulignent l’intérêt d’un traitement multimodal, incluant la rhéophérèse comme thérapie prometteuse lorsque l’arrêt des AVK est impossible. Les deux patients ont présenté une calciphylaxie urémique sévère sous AVK en raison d’une valve mécanique mitrale. Ils ont bénéficié d’un traitement multimodal intensif, incluant une hémodialyse quotidienne, du thiosulfate de sodium intraveineux, des calcimimétiques, des chélateurs du phosphate, des analgésiques opioïdes et une évaluation en chirurgie plastique. Un traitement par rhéophérèse a été initié deux fois par semaine pendant quatre mois, période pendant laquelle les AVK ont été maintenus. La fréquence des séances de rhéophérèse a ensuite été progressivement réduite. La guérison complète des plaies a été obtenue en sept mois. Les deux patients ont ensuite bénéficié d’une parathyroïdectomie devant une hyperparathyroïdie tertiaire. À notre connaissance, il s’agit des premiers cas rapportés de rémission complète de calciphylaxie urémique sans interruption des AVK. Cette stratégie de traitement multimodal et multidisciplinaire pourrait représenter une approche efficace chez les patients anticoagulés à haut risque.

#4

Wound Management and Surgery for Calcific Uremic Arteriolopathy (Calciphylaxis): A Retrospective Observational Cohort Study.

International wound journal2026 Mar

Wound care in calciphylaxis remains poorly defined without evidence-based consensus on timing and technique of surgical intervention. We demonstrate that surgical debridement and subsequent wound closure are safe and effective in calciphylaxis and describe a systematic multidisciplinary approach to intervention. We retrospectively reviewed a cohort of patients with calciphylaxis at our institution. Those who underwent surgical debridement and wound closure were analysed with emphasis on wound healing, progression to amputation and mortality. Sixty-two patients with calciphylaxis underwent surgical debridement. Twenty patients had wound closure by skin grafting, five were excised with primary wound closure, and 37 were debrided and allowed to heal by secondary intention. There were excellent rates of healing in all groups, and no patients demonstrated wound progression or new lesions following operative intervention. Surgical debridement and wound closure are safe and effective in treating wounds related to calciphylaxis.

#5

Postparathyroidectomy calciphylaxis in a patient with primary hyperparathyroidism: a rare complication.

JCEM case reports2026 Mar

Calciphylaxis, a rare and life-threatening condition involving calcification of small to medium-sized arterioles in subcutaneous tissue, leads to ischemia and necrosis. While typically seen in chronic kidney disease (CKD), a small proportion of cases can present without CKD, referred to as nonuremic calciphylaxis (NUC). NUC associated with primary hyperparathyroidism is rare with limited evidence-based management. A 41-year-old woman with no prior medical history presented with cardiac arrest due to severe hypercalcemia of 17.87 mg/dL (4.46 mmol/L) (normal reference range, 8.6-10.3 mg/dL; 2.2-2.6 mmol/L) and markedly elevated parathyroid hormone (PTH) levels. She required intensive care and extracorporeal membrane oxygenation (ECMO). Following stabilization, she underwent emergency parathyroidectomy for a parathyroid adenoma. During her prolonged recovery over 100 days, she developed painful necrotic skin lesions. Histopathology confirmed calciphylaxis. Management was conservative, involving wound care and analgesia, without surgical debridement. Her skin lesions resolved, and she has remained free of recurrence with stable calcium and PTH levels for more than 10 years. NUC following parathyroidectomy for primary hyperparathyroidism is rare. Multifactorial causes could contribute to the pathogenesis of calciphylaxis in our case, involving acute kidney injury, ECMO, and prolonged immobility. Early recognition and multidisciplinary management are crucial given the high mortality rate in calciphylaxis.

Publicações recentes

Lived experiences of patients with calciphylaxis (CALCI-E): a qualitative study.

J Nephrol2026 Mar 16

Hyperbaric oxygen treatment as a therapeutic option for penile calciphylaxis.

Asian J Urol2026 Jan

[Challenges of ongoing VKA use in calciphylaxis: The potential of multimodal treatment including rheopheresis, — a case report].

Nephrol Ther2026 Apr 3

Wound Management and Surgery for Calcific Uremic Arteriolopathy (Calciphylaxis): A Retrospective Observational Cohort Study.

Int Wound J2026 Mar

Postparathyroidectomy calciphylaxis in a patient with primary hyperparathyroidism: a rare complication.

JCEM Case Rep2026 Mar

Ver todas no PubMed

📚 EuropePMC1.355 artigos no totalmostrando 195

Lived experiences of patients with calciphylaxis (CALCI-E): a qualitative study.

Hyperbaric oxygen treatment as a therapeutic option for penile calciphylaxis.

Asian journal of urology

Nephrologie & therapeutique

[Challenges of ongoing VKA use in calciphylaxis: The potential of multimodal treatment including rheopheresis, — a case report].

International wound journal

Wound Management and Surgery for Calcific Uremic Arteriolopathy (Calciphylaxis): A Retrospective Observational Cohort Study.

Postparathyroidectomy calciphylaxis in a patient with primary hyperparathyroidism: a rare complication.

JCEM case reports

An Atypical Presentation of Cutaneous Angiosarcoma: A Diagnostic Challenge in an End-Stage Renal Disease Patient.

The American Journal of dermatopathology

Diffuse Dermal Angiomatosis of the Breast Presenting as Diffuse Erythema Mimicking Inflammatory Breast Carcinoma in a Healthy Pregnant Patient.

Resolution of penile calciphylaxis in a high-risk dialysis patient with medical therapy and wound care.

BMJ case reports

Amputation and reamputation for dry gangrene of both lower extremities in with chronic kidney disease patients with calciphylaxis accompanied by multidrug-resistant bacterial infections: A case report and literature analysis.

Medicine

Ocular Calciphylaxis in a 46-year-old Man on Hemodialysis.

Ophthalmology

International journal of surgery case reports

Benign but bizarre: A case report on idiopathic scrotal calcinosis.

Calciphylaxis in a patient with end-stage renal disease: Multimodality imaging and clinical correlation.

Radiology case reports

Atypical Calciphylaxis Following Parathyroidectomy and Persistent Severe Hypocalcemia in a Hemodialysis Patient: A Case Report.

Case reports in nephrology

Calciphylaxis in the Upper GI Tract in an ESRD Patient: An Atypical Presentation and Review of Literature.

Idiopathic Penile Calcinosis Cutis: A Histopathological Case Report.

Reports (MDPI)

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia

Calcific Uremic Panniculitis: A Rare Form of Calciphylaxis in an Endstage Renal Disease Patient.

Navigating Calciphylaxis in End-Stage Renal Disease: A Case Report Highlighting the Complexities of Pain Control and the Need for Greater Clinical Vigilance.

Critical Limb Ischaemia in a Patient With Subcutaneous Nodules: Clues to a Hidden Systemic Disease.

Journal of multidisciplinary healthcare

The Skin: A Critical Window into Chronic Kidney Disease and a Call for Collaborative Care.

Paradoxical effects of parathyroidectomy and sodium thiosulfate in a hemodialysis patient with calciphylaxis: a case report of persistent metastatic calcification.

Frontiers in medicine

Calciphylaxis diagnosis, management and future directions: a comprehensive update on behalf of the European Renal Association CKD-MBD Working Group.

Clinical kidney journal

Progressive painful skin lesions in a patient with end-stage renal disease.

Multi-site Calciphylaxis With Pulmonary Calcification in a Young Haemodialysis Patient.

American journal of kidney diseases : the official journal of the National Kidney Foundation

Skin Disorders in Kidney Disease: Core Curriculum 2026.

Calciphylaxis Raising Suspicion for Factitious Dermatitis: A Diagnostic Challenge.

A study of three cases of acquired reactive perforating collagenosis mimicking calciphylaxis.

BMC nephrology

Oxford medical case reports

Managing anticoagulation in a patient with Calciphylaxis and mechanical valve: a therapeutic dilemma.

A case of penile calciphylaxis development shortly after initiation of dialysis for graft dysfunction following living donor kidney transplantation: a case report.

BMC nephrology

Case reports in dermatology

A Case Report of Non-Uremic Calciphylaxis Refractory to Treatment Requiring Multidisciplinary Care.

The Journal of clinical investigation

Pharmacological targeting of the IL-17/neutrophil axis attenuates calcific deposits in rat models of calciphylaxis.

The journal of sexual medicine

Systematic review of penile glans necrosis.

Advances in skin & wound care

A Composite Dermal Matrix Comprising Ovine Forestomach Matrix and Hyaluronic Acid in the Treatment of Chronic Wounds Secondary to Calciphylaxis: A Case Series and Literature Review.

Nonuremic penile calciphylaxis treated with pentoxifylline.

Healthcare (Basel, Switzerland)

Surgical Approach in the Treatment of Calciphylaxis: A Case Report.

Italian journal of dermatology and venereology

Rituximab-induced nonuremic calciphylaxis in hairy cell leukemia: a singular case.

Indian journal of nephrology

Penile Calciphylaxis: A Rare and Life-Threatening Condition.

The Journal of surgical research

Elevated Perioperative Morbidity After Parathyroidectomy for Calciphylaxis Patients: A Nationwide Retrospective Observational Study.

Journal of education & teaching in emergency medicine

A Case Report of Calciphylaxis.

Penile Calciphylaxis: Two Clinical Cases and a Literature Review.

Aiming for calciphylaxis prophylaxis.

Translational andrology and urology

Penile calciphylaxis: surgical management in the setting of Fournier's gangrene-a case report and literature review.

bioRxiv : the preprint server for biology

A Novel FNDC1-NAMPT-NAD axis is Implicated in Small and Large-vessel Arterial Disease and Drives Vascular Calcification.

The CALCIPHYX trial and its impact on calciphylaxis treatment: what's next?

Clinical kidney journal

Journal of Brown hospital medicine

Warfarin Induced Non-Uremic Calciphylaxis.

Navigating the patient-provider relationship during severe illness with lessons from a qualitative perspective of calciphylaxis.

Scientific reports

Ten tips on how to deal with calciphylaxis patients.

Clinical kidney journal

Oxford medical case reports

Chronic leg ulcers in a patient with Hyperoxaluria type 1: a rare and challenging diagnosis.

International wound journal

Pathophysiology of Wound Development and Chronicity in Renal Disease: A Narrative Review.

Pain medicine case reports

Buprenorphine for the Management of Intractable Pain in Skin Ulcers Associated With Calcific Uremic Arteriolopathy.

Clinical and experimental dermatology

Intralesional sodium thiosulfate is an effective treatment for nonuraemic calciphylaxis.

Mediterranean journal of rheumatology

Calciphylaxis: A Mimic of Vasculitis.

Calciphylaxis: A Rare Manifestation of a Common Disease.

Part II. Dermatologic Manifestations Associated with Treatment of Patients with Kidney Disease.

Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria

[Translated article] Multicenter retrospective analysis of sodium thiosulfate as treatment for non-uremic calciphylaxis.

Calciphylaxis in End-Stage Renal Disease: A Case of Nonhealing Ulcer and Diagnostic Challenges.

Treatment effects of human amnion-derived mesenchymal stem cells for skin lesions and metastatic pulmonary calcification in calciphylaxis patients - case series and literature review.

World journal of radiology

Calciphylaxis following liver transplantation in a patient with end-stage renal disease: A case report.

Penile Abscess Complicating Chronic Penile Calciphylaxis in a Heart Transplant Recipient and End-Stage Renal Disease Patient.

Calcinosis Cutis With Selective Fibroblast Growth Factor Receptor Inhibitors: A Case Report and Review of Literature.

Calcific uremic arteriolopathy with penile involvement post-kidney transplant.

Urology case reports

Nature reviews. Nephrology

IL-6 signalling contributes to the pathogenesis of uraemic calciphylaxis.

Internal medicine (Tokyo, Japan)

Extensive Visceral Calciphylaxis in a Patient with End-stage Renal Disease: A Postmortem Revelation.

SAGE open medical case reports

Cutaneous cytomegalovirus in mixed serostatus kidney transplant patient.

Journal of cutaneous medicine and surgery

Clinical Features and Treatment Outcomes of Cutaneous Calciphylaxis in Paediatric Patients: A Systematic Review.

Histologic comparison of normal and diseased skin in patients with suspected calciphylaxis.

Outcomes and mortality in calciphylaxis: A multicenter update.

Kidney transplantation and hyperbaric oxygen treatment for calciphylaxis.

Kidney international

The Journal of dermatology

Calciphylaxis Triggered by Acute Kidney Injury and Malignancy: A Successfully Treated Case.

Wounds : a compendium of clinical research and practice

Topical timolol for calciphylaxis: a case report.

Diagnostics (Basel, Switzerland)

Calciphylaxis of the Upper Limbs-A Rare and Serious Disease with Multidisciplinary Treatments-A Case Series and Literature Review.

Calciphylaxis in the Setting of Acute Kidney Injury.

Direct immunofluorescence testing for panniculitis offers negligible diagnostic utility: A retrospective single-center cohort study of 87 specimens.

Case reports in nephrology and dialysis

Acute Visual Loss and Mesenteric Nodules: Two Case Reports of Atypical Presentations of Calciphylaxis.

Pharmaceuticals (Basel, Switzerland)

Hexasodium Fytate (SNF472 or CSL525) Inhibits Ectopic Calcification in Various Pseudoxanthoma Elasticum and Calcinosis Cutis Animal Models.

Science translational medicine

Activation and targetability of TYMP-IL-6-TF signaling in the skin microenvironment in uremic calciphylaxis.

Calciphylaxis Penile Lesion: An Unusual Complication of End-Stage Renal Disease.

International urology and nephrology

Autologous platelet-rich plasma therapy for skin ulceration due to calcific uremic arteriopathy: a case report and review of the literature.

Laboratory investigation; a journal of technical methods and pathology

Multicenter Evaluation of Certainty and Reliability in Calciphylaxis Diagnosis Using a Digital Imaging Platform.

Calcific Uremic Arteriolopathy in Hemodialysis Patients: A Report of Two Cases and Review of the Literature.

Calciphylaxis Following Parathyroidectomy in Chronic Kidney Disease Patients-Case Report and Literature Review.

Biomedicines

Corrigendum for the article Clin Nephrol. 2025; 103: 1-4.

Clinical nephrology

Journal of molecular cell biology

Calciphylaxis: ongoing challenges and treatment opportunities with mesenchymal stem cells.

Kansas journal of medicine

A Case Report of Futibatinib-Induced Calciphylaxis.

The American journal of forensic medicine and pathology

Getting Crunchy With COVID-19: A Unique Case of Catastrophic Multiorgan Calciphylaxis.

Nonbacterial Thrombotic Endocarditis of a Mitral Prosthesis After Warfarin, Enoxaparin, and Apixaban Failure.

JACC. Case reports

Neuro-ophthalmology (Aeolus Press)

Calciphylaxis in a Middle-Aged Asian Patient: An Unusual Cause of Disc Swelling.

A Rare Case of Calciphylaxis: A Case Report.

Biomedicine hub

Journal of the Belgian Society of Radiology

Imaging Features of Calciphylaxis on Conventional Radiography and Computerized Tomography.

Clinical nephrology. Case studies

Non-uremic calciphylaxis: A dermatologic complication in both MASH and alcohol-associated cirrhosis.

Healthcare (Basel, Switzerland)

Successful Management of Calciphylaxis with Sodium Thiosulfate in End-Stage Renal Disease: A Case Report.

Calciphylaxis in the absence of pathological skin lesions.

BMJ case reports

Calciphylaxis: Beating the Odds.

The Journal of dermatology

A case of non-uremic calciphylaxis in a patient with secondary hyperparathyroidism and panhypopituitarism.

AACE clinical case reports

Uremic Leontiasis Ossea due to Resistant Secondary Hyperparathyroidism.

The Veterinary clinics of North America. Equine practice

Myosin Heavy Chain Myopathy and Immune-Mediated Muscle Disorders.

Anais brasileiros de dermatologia

Livedoid vasculopathy, calciphylaxis, and Martorell's hypertensive ulcer: update on ischemic ulcers due to impaired microcirculation of the lower limbs.

Hemodialysis international. International Symposium on Home Hemodialysis

Sodium Thiosulfate Treatment for Calciphylaxis: Is There an Optimal Duration of Therapy?

Advances in skin & wound care

Managing Calciphylaxis: Insights from Real-World Cases at a Tertiary Academic Center.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases

Calciphylaxis in Coexistent Primary and Secondary Hyperparathyroidism.

Risk Factors Associated With the Development of Calciphylaxis in Patients With Chronic Kidney Disease: A Systematic Review.

Pharmaceuticals (Basel, Switzerland)

Sodium Thiosulfate: An Innovative Multi-Target Repurposed Treatment Strategy for Late-Onset Alzheimer's Disease.

Characteristics and prognostic values of abdominal aortic branches calcification in hemodialysis patients.

Calciphylaxis: A Case Report and Review of the Role of Sodium Thiosulphate and Other Treatment Modalities.

Course and treatment of severe osteoporosis complicated by calciphylaxis: a case report.

JBMR plus

Calcific Uremic Arteriolopathy (CUA) Among Malaysian Dialysis Patients: Clinical Characteristics, Treatment, and Outcomes.

Expert opinion on drug safety

Anticoagulant-associated calciphylaxis: analysis of USFDA adverse event report system and clinical feature analysis of reported cases.

Outcomes in an educational skin-model session on point-of-care ultrasound for diagnosing calciphylaxis.

Skin health and disease

Calciphylaxis in a Patient on Hemodialysis: A Case Report.

Annales de dermatologie et de venereologie

Hyperbaric oxygen therapy enables pain reduction and healing in painful chronic wounds, including in calciphylaxis.

The American Journal of dermatopathology

Redefining Calciphylaxis as a Uniquely Bone Forming Subcutaneous C5b-9-Mediated Microvascular Injury Syndrome Associated With Localized Subcutaneous and Systemic Complement Pathway Activation.

Hyperbaric oxygen treatment in addition to conventional multidisciplinary care in patients with calciphylaxis.

Clinical nephrology

Gastrointestinal calciphylaxis: a rare and devastating complication in end-stage kidney disease.

CEN case reports

Wounds : a compendium of clinical research and practice

A case of rapidly progressive unilateral non-nephrogenic hemorrhagic bullous calciphylaxis responding to systemic sodium thiosulfate therapy.

Case reports in ophthalmology

Calciphylaxis Mimicking Giant Cell Arteritis: A Case Report.

Penile Calciphylaxis: A Rare-Case Report of Calcific Uremic Arteriolopathy in a Patient with End-Stage Renal Disease and Severe Vascular Insufficiency.

Indian journal of nephrology

Relapsing Calciphylaxis of the Breast: Glucocorticoids - Friend or Foe?

[Endogenous skin overloads].

Annales de pathologie

Calciphylaxis and metastatic calcification.

Inositol Hexaphosphate in Bone Health and Disease.

Biomolecules

Surgical Management of Penile Calciphylaxis Without Penectomy.

Penile Calciphylaxis Obscured by Phimosis in an End-Stage Renal Disease Patient: A Case Report.

Calciphylaxis in a 30-Year-Old Woman With Alcoholic Cirrhosis: A Case Report.

Hexasodium fytate for the treatment of calciphylaxis: a randomised, double-blind, phase 3, placebo-controlled trial with an open-label extension.

EClinicalMedicine

Advanced Calciphylaxis in a Patient With End-Stage Renal Disease: A Case Report Highlighting Diagnostic and Therapeutic Challenges in Late-Stage Presentation.

Individualizing the lifesaving journey for calciphylaxis: addressing rapidly progressive attacks with multidimensional and AI research for regenerative medicine.

Updated solution for diagnosis and management of calcinosis cutis: A retrospective review.

Medicine

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

Intravenous treatment of calcinosis cutis with sodium thiosulfate - A case series.

Deutsches Arzteblatt international

The Differential Diagnosis of Leg Ulcers.

Clinical journal of the American Society of Nephrology : CJASN

The Relevance of Phytate for the Treatment of Chronic Kidney Disease.

Interactive journal of medical research

Emerging Indications for Hyperbaric Oxygen Treatment: Registry Cohort Study.

A Rare Case of Calcinosis Cutis Presenting to a Tertiary Care Hospital in Rural Maharashtra.

Assessment of diagnostic delay, morbidity, and mortality outcomes in 302 calciphylaxis patients over a 17-year period: A retrospective cohort study.

Nitric oxide : biology and chemistry

Sodium thiosulfate: A donor or carrier signaling molecule for hydrogen sulfide?

Journal of surgical case reports

Non-chronic kidney disease-induced calciphylaxis: a rare case report.

Kidney international reports

Calciphylaxis Episodes in the Australia and New Zealand Dialysis and Transplant Registry.

The Accelerated Onset of Calciphylaxis in a 72-Year-Old Female Hemodialysis Patient.

[Calciphylaxis, risk factors, treatment and outcomes. Retrospective study of 39 patients].

Medicina

The Australasian journal of dermatology

Evaluating the role of bone scan in diagnosing calciphylaxis in practice-A retrospective case series of patients who were clinically managed for calciphylaxis despite resulting negative on initial biopsy.

Journal of palliative medicine

Calciphylaxis and Intractable Pain in a Veteran with Psychological Trauma History.

Nephrologie & therapeutique

[The highlights of dialysis in 2023].

World journal of nuclear medicine

Potential Role of Bone Scintigraphy in the Diagnosis of Calciphylaxis.

Indian journal of dermatology, venereology and leprology

Aluminium in dermatology - Inside story of an innocuous metal.

Current opinion in nephrology and hypertension

New therapeutic perspectives for vascular and valvular calcifications in chronic kidney disease.

Progression of Skin Ulcer Secondary to Calciphylaxis in a Patient With End-Stage Renal Disease (ESRD) on Hemodialysis and the Therapeutic Approach.

Penile Calciphylaxis: A Successfully Treated Case.

Histopathology and radiologic imaging for the confirmation of calciphylaxis in a diverse population: A retrospective cohort study.

SNF472: a novel therapeutic agent for vascular calcification and calciphylaxis.

International journal of dermatology

Successful treatment of non-uremic calciphylaxis with combination therapy with sodium thiosulfate, iloprost, and heparin.

Journal of gastrointestinal oncology

Management and mechanism of calciphylaxis in a patient treated with the FGFR inhibitor pemigatinib-a case report.

Journal of the American Podiatric Medical Association

Nonuremic Calciphylaxis: A Rare and Unexpected Diagnosis of Necrotic Ulcers.

Rare (Amsterdam, Netherlands)

Calciphylaxis in POEMS syndrome: Case report.

A Peculiar Presentation of a Debilitating Condition: Calciphylaxis.

Inflammatory and vaso-occlusive ulcers: Part I - Clinical presentation and diagnosis.

Indian journal of pathology & microbiology

Evaluation of the histopathological spectrum of skin biopsies in patients with chronic kidney disease: A single-center experience.

Prevalence and risk factors for development of recurrent calciphylaxis.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

Occlusive cutaneous vasculopathies as cause of chronic ulcers.

Coexistence of nephrogenic systemic fibrosis and calciphylaxis in a gadolinium-naïve, chronic haemodialysis patient.

BMJ case reports

Clinical characteristics and treatment modalities in uremic and non uremic calciphylaxis - a dermatological single-center experience.

Clinical nephrology. Case studies

Calciphylaxis, beware the ophthalmic mimic: A case series.

Vascular medicine (London, England)

Images in Vascular Medicine: Nonuremic calciphylaxis secondary to occult malignancy.

Journal of investigative medicine high impact case reports

Calciphylaxis in a Patient With Lupus Nephritis and Acute Kidney Injury: A Rare Case Report and Literature Review.

Repeat, Bilateral Femoral Nerve Blocks With Liposomal Bupivacaine for Analgesia in a Patient With Calciphylaxis: A Case Report.

A&A practice

Endocrinology, diabetes & metabolism case reports

Calciphylaxis in a patient with hypoparathyroidism and MEN-1 syndrome.

Calciphylaxis: An Unusual and Silent Usher for an Underlying Carcinoma.

Journal of drugs in dermatology : JDD

Intralesional Sodium Thiosulfate as Adjuvant Therapy in Severe Calciphylaxis.

Calcific Uremic Arteriolopathy in End-Stage Renal Disease: A Rare Life-Threatening Condition.

Role of bone scan in diagnosis of calciphylaxis: A review.

JAAD international

Wounds : a compendium of clinical research and practice

Surgical management of pain or infection secondary to calciphylaxis: a wound center's experience and algorithmic multidisciplinary approach.

International journal of dermatology

Intralesional sodium thiosulfate for the treatment of calciphylaxis: a case report and review of the literature.

Uremic Bilateral Breast Calciphylaxis: A Case Report and Literature Review.

Calciphylaxis: A Rare Complication With a Fatal Outcome in End-Stage Renal Disease.

Black necrosis of the glans penis associated with calciphylaxis: A case report.

Medicine

Scrotal calciphylaxis in a fifty-one-year-old man with end-stage renal disease and prior bacteremia.

Urology case reports

Annals of medicine and surgery (2012)

Calciphylaxis during the course of psoriatic arthritis patient. Is it coincidence? A case report.

Calciphylaxis Secondary to Vitamin D Supplementation.

Sailing between scylla and charybdis-anticoagulation dilemma in a patient with calciphylaxis and mechanical cardiac valve replacement: a case report and literature review.

Early diagnosis strategy of calciphylaxis in dialysis patients.

Risk factors, treatment modalities, and clinical outcomes of penile calciphylaxis: systematic review.

World journal of urology

Indian journal of nephrology

Penile Calciphylaxis - A Rare, Yet Medically Treatable Disease.

Wounds : a compendium of clinical research and practice

Clinical management of nonuremic calcific arteriolopathy: a report of three cases.

Influence of sodium thiosulfate on coronary artery calcification of patients on dialysis: a meta-analysis.

Elastic fiber alterations and calcifications in calcific uremic arteriolopathy.

Scientific reports

Multimodality approach to treat calciphylaxis in end-stage kidney disease patients.

Non-uremic Calciphylaxis With Possible Initial Misdiagnosis as Erythema Multiforme/Toxic Epidermal Necrolysis Successfully Treated as Inpatient.

Penile calciphylaxis, infrequent complication with bad prognosis: a case report.

Urology case reports

Differential diagnosis of stage 2, 3 and 4 pressure injuries of the pelvis and lower extremity: a case series.

Journal of wound care

Distinguishing dystrophic calcification from calciphylaxis.

A Rare Case of Post-parathyroidectomy Calciphylaxis in a Young Patient With End-Stage Renal Disease: A Case Report and Literature Review.

A retrospective review of outcomes after hyperbaric oxygen therapy for the treatment of calciphylaxis.

Medicina (Kaunas, Lithuania)

Sodium Thiosulfate for Calciphylaxis Treatment in Patients on Peritoneal Dialysis: A Systematic Review.

Current protein & peptide science

Phosphate Toxicity and Vascular Calcification in Chronic Kidney Disease: A Closer Look Utilizing Transmission Electron Microscopy.

American journal of nephrology

Nephrogenic Calciphylaxis Arising after Bariatric Surgery: A Case Series.

Cutaneous vascular calcifications in patients with chronic kidney disease and calcific uremic arteriolopathy: a cross-sectional study.

Hinyokika kiyo. Acta urologica Japonica

[A Case of Penile Calciphylaxis in a Hemodialysis Patient].

A case of nonuremic calciphylaxis of the penis responding to sodium thiosulfate therapy.

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