Raras
Buscar doenças, sintomas, genes...
Doença enxerto versus hospedeiro, crônica
ORPHA:99921CID-10 · T86.0CID-11 · 4B24.1DOENÇA RARA

A Doença do Enxerto Contra o Hospedeiro Crônica (DECH) é uma complicação que pode acontecer depois de um transplante de células-tronco ou de medula óssea. Nela, as células do doador, que foram recém-transplantadas, atacam o corpo de quem recebeu o transplante. Os sintomas podem incluir erupções na pele (como manchas ou vermelhidão), feridas na boca, olhos secos, inflamação no fígado, formação de cicatrizes na pele e nas articulações, e danos aos pulmões. A causa exata da DECH crônica não é conhecida. Provavelmente, ela resulta de uma interação complexa entre as células do doador e as de quem recebeu o transplante, que é mediada pelo sistema de defesa do corpo (sistema imunológico). A DECH crônica é tratada com prednisona ou outros medicamentos anti-inflamatórios ou imunossupressores (que diminuem a ação do sistema de defesa do corpo) semelhantes.

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Introdução

O que você precisa saber de cara

📋

A Doença do Enxerto Contra o Hospedeiro Crônica (DECH) é uma complicação que pode acontecer depois de um transplante de células-tronco ou de medula óssea. Nela, as células do doador, que foram recém-transplantadas, atacam o corpo de quem recebeu o transplante. Os sintomas podem incluir erupções na pele (como manchas ou vermelhidão), feridas na boca, olhos secos, inflamação no fígado, formação de cicatrizes na pele e nas articulações, e danos aos pulmões. A causa exata da DECH crônica não é conhecida. Provavelmente, ela resulta de uma interação complexa entre as células do doador e as de quem recebeu o transplante, que é mediada pelo sistema de defesa do corpo (sistema imunológico). A DECH crônica é tratada com prednisona ou outros medicamentos anti-inflamatórios ou imunossupressores (que diminuem a ação do sistema de defesa do corpo) semelhantes.

Publicações científicas
5.485 artigos
Último publicado: 2026 Mar 14
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SUS: Sem cobertura SUSScore: 0%
CID-10: T86.0
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Entender a doença

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Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🫃
Digestivo
10 sintomas
🫁
Pulmão
7 sintomas
🧬
Pele e cabelo
6 sintomas
💪
Músculos
4 sintomas
👁️
Olhos
3 sintomas
📏
Crescimento
2 sintomas

+ 16 sintomas em outras categorias

Características mais comuns

90%prev.
Cicatrização de feridas pobre
Muito frequente (99-80%)
90%prev.
Pele espessada
Muito frequente (99-80%)
90%prev.
Erupção papular eritematosa generalizada intermitente
Muito frequente (99-80%)
55%prev.
Bronquiectasia
Frequente (79-30%)
55%prev.
Erosões corneanas recorrentes
Frequente (79-30%)
55%prev.
Ceratoconjuntivite seca
Frequente (79-30%)
53sintomas
Muito frequente (3)
Frequente (13)
Ocasional (37)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 53 características clínicas mais associadas, ordenadas por frequência.

Cicatrização de feridas pobrePoor wound healing
Muito frequente (99-80%)90%
Pele espessadaThickened skin
Muito frequente (99-80%)90%
Erupção papular eritematosa generalizada intermitenteIntermittent generalized erythematous papular rash
Muito frequente (99-80%)90%
BronquiectasiaBronchiectasis
Frequente (79-30%)55%
Erosões corneanas recorrentesRecurrent corneal erosions
Frequente (79-30%)55%

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico5.485PubMed
Últimos 10 anos200publicações
Pico2026106 papers
Linha do tempo
2026Hoje · 2026🧪 1931Primeiro ensaio clínico
Publicações por ano (últimos 10 anos)

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Genética e causas

O que está alterado no DNA e como passa nas famílias

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Nenhum gene associado encontrado

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Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

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Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

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Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Doença enxerto versus hospedeiro, crônica

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Ensaios clínicos abertos e novidades científicas recentes

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Publicações mais relevantes

Timeline de publicações
2.707 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 2.707

#1

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia.

Pediatric blood & cancer2026 Mar 19

A second allogeneic (allo-)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant-related toxicity in highly pretreated patients. This retrospective multicenter study analyzed 75 pediatric patients enrolled in the PRSZT registry who underwent HSCT2 between 2011 and 2020. Indications for HSCT2 were relapse in 55 patients (73%) and graft failure in 16 patients (21%). In 4 patients (6%), the indication could not be clearly determined due to incomplete documentation. At 2 and 5 years, overall survival (OS) was 48% and 40%, while relapse-free survival (RFS) was 35.2% and 29.9%. Relapse was the leading cause of mortality, occurring in 36% of patients post-HSCT2, with a median time to relapse of 8.2 months. Univariate analysis identified a longer duration of remission after HSCT1 (>6 months) as a predictor of improved OS (p = 0.013) and chronic graft-versus-host disease (cGVHD) after HSCT2 as beneficial for OS (p = 0.034) and RFS (p = 0.024). In multivariate analysis, older age (>10 years) (HR: 2.778, p < 0.01) and precursor T-cell ALL (HR: 6.62, p = 0.001) were associated with inferior OS, as well as with inferior RFS (HR: 2.2, p = 0.03; HR: 3.89, p < 0.005), while male sex (HR: 0.354, p = 0.02) and ATG administration (HR: 0.35, p = 0.019) predicted improved OS. Despite high relapse rates, HSCT2 remains a potentially curative treatment in a subgroup of patients. These findings highlight the need for better patient selection and the integration of novel immunotherapeutic strategies to further improve outcomes.

#2

Ferritin as a pre-transplant biomarker for post-transplant outcomes in allogeneic stem cell transplantation using post-transplant cyclophosphamide.

Transplantation and cellular therapy2026 Mar 14

Iron overload, indicated by elevated ferritin, is a potentially modifiable risk factor in allogeneic hematopoietic cell transplantation (allo-HCT); however, its prognostic value remains uncertain. We evaluated whether pre-transplant ferritin (pre-TF) levels are associated with allo-HCT outcomes, including overall survival (OS), disease-free survival (DFS), relapse incidence, and GVHD incidence. We retrospectively analyzed 682 allo-HCT recipients transplanted between 2019 and 2022, with a median follow-up 37 months. Pre-TF was measured at a median of 17 days before allo-HCT. A time-dependent receiver operating characteristic analysis for 2-year OS defined the optimal pre-TF cut-off of 2209 µg/L (AUC 0.53, sensitivity 35%, specificity 75%). Propensity score matching (PSM) was performed at a 2:1 ratio (controls:cases, caliper 0.2), balancing pre-transplant characteristics to yield a matched cohort of 417 patients. The median pre-TF was 1159 µg/L. After PSM, 278 patients (66.7%, n=278/417) had low pre-TF (< 2209 µg/L), and 139 (33.3%) had high pre-TF (≥ 2209 µg/L). High pre-TF was associated with a higher relapse incidence (HR 1.484, 95% CI 1.019-2.160, p=0.039) and a lower incidence of moderate or severe chronic graft-versus-host disease (cGvHD) (HR 0.501, 95% CI 0.298-0.843, p=0.009). OS did not differ after PSM, and was primarily influenced by HCT-CI and conditioning intensity. No differences were observed in graft dynamics, immune reconstitution, or infections. An exploratory AML-specific analysis (cut-off of 2885 µg/L) showed similar patterns for DFS and cGvHD. Elevated pre-transplant ferritin identifies allo-HCT patients at a higher relapse risk and lower risk of cGvHD. These results suggest that ferritin may be associated with immunomodulatory effects that attenuate the graft-versus-leukemia effect while reducing graft-versus-host disease, although this requires further investigation. Clinically, ferritin may serve as a simple and accessible risk biomarker, warranting prospective validation with disease-specific thresholds and integration of functional iron measures.

#3

Early Marrow Microenvironment Immune Patterns After Hematopoietic Stem Cell Transplant in Pediatric Acute Lymphoblastic Leukemia Are Associated with Later Development of Chronic GvHD and Relapse.

International journal of molecular sciences2026 Mar 02

Hematopoietic stem cell transplant (HSCT) is a curative therapy for acute lymphoblastic leukemia (ALL), but its success is limited by chronic graft-versus-host disease (cGvHD) and disease relapse. A central challenge is uncoupling the graft-versus-leukemia (GvL) effect from cGvHD. Early changes in the bone marrow microenvironment following HSCT may offer a predictive window into these divergent outcomes. We conducted a retrospective, single-center, exploratory study on 14 pediatric ALL HSCT patients. Applying single-cell antibody-sequencing (AbSeq) on archived bone marrow aspirates collected 60-100 days post-HSCT, we evaluated immune patterns associated with the development of cGvHD or ALL relapse after day 114. cGvHD after day 114 was associated with upregulation of the endoplasmic reticulum (ER) stress transcription factor XBP1 in transitional B cell and IgM memory B cell populations, a minclehighPD1- neutrophil population, and exhausted LAG3+ effector memory T cells (TEM). ALL relapse after day 114 was associated with higher CD22, CD24, and ARG1 expression in M(IL-4)-like macrophages and exhausted TIGIT+ TEM. Results from this exploratory study suggest that marrow immune signatures of B cell ER stress preceding later development of cGvHD and macrophage-mediated immune evasion preceding relapse may potentially be early biomarkers for separating GvL from cGvHD in ALL HSCT. Validation with larger cohorts is warranted.

#4

Neuromyelitis Optica Spectrum Disorder in a Pediatric Patient Following Haploidentical Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia.

Blood cell therapy2026 Feb 25

This report describes a rare pediatric case of seronegative neuromyelitis optica spectrum disorder (NMOSD) following a second haploidentical hematopoietic stem cell transplantation (HSCT) for relapsed acute myeloid leukemia (AML). The neurological syndrome, featuring simultaneous optic neuritis and myelitis, emerged alongside classic chronic graft-versus-host disease (GVHD) manifestations (lichenoid oral changes, arthritis) on day +145 post-transplant. The diagnosis of seronegative NMOSD was established based on clinical and MRI findings, after exclusion of infectious etiologies and absence of aquaporin-4 IgG antibodies in blood and cerebrospinal fluid. Corticosteroids were avoided due to the risk of AML relapse. Instead, plasma exchange, immunotherapy with rituximab and cyclophosphamide, followed by intravenous immunoglobulin maintenance induced rapid neurological improvement and parallel resolution of GVHD symptoms. This case underscores the central nervous system as a target for alloimmunity and presents a successful steroid-sparing treatment strategy for NMOSD manifested after allogenic HSCT.

#5

Tooth loss and oral health-related quality of life in a sub-cohort within the Chronic Graft-versus-Host Disease Consortium.

Transplantation and cellular therapy2026 Mar 07

Chronic graft-versus-host-disease (cGVHD) is a major complication of allogeneic hematopoietic cell transplantation (alloHCT) that frequently affects the oral cavity with manifestations of oral mucosal inflammation, salivary gland hypofunction, and trismus. However, the long-term consequences of oral cGVHD on oral health outcomes are not defined. This report assesses long-term tooth loss and oral health-related quality of life (OHRQL) measures in patients who have received alloHCT. Participants were evaluated at an initial post-transplant dental visit which consisted of dental and periodontal examination, oral mucosal examination, and panoramic radiographs. The National Institutes of Health (NIH) Modified Oral Mucosa Rating Scale (OMRS) and World Health Organization (WHO) Oral Health Assessment for Adults were used for diagnosis and grading of oral cGVHD and dental status. Pre-transplant dental records were available and utilized to calculate tooth loss data. Participants also completed the Oral Health Impact Profile-14 (OHIP-14) questionnaire, the NIH mouth sensitivity score, the Lee Symptom Scale (oral cavity items), and the shortened summated Xerostomia Inventory (XI). This study enrolled 70 participants at a median of 8.8 years after alloHCT (range 6.7-11.8 years); 19 (27.1%) had no past oral cGVHD, 22 (31.4%) had past but no current oral cGVHD, and 29 (41.4%) had current oral cGVHD. Patients with current oral cGVHD had a mean tooth loss of 2.3, patients with past but no current oral cGVHD had a mean tooth loss of 1.0, and patients with no past oral cGVHD had a mean tooth loss of 2.1 (p=0.54, ANOVA). The mean overall OHIP-14 scores for the current, past but no current, and no past oral cGVHD groups were 13.6, 6.3, and 6.3, respectively (p=0.02, ANOVA). Oral cGVHD significantly impacted various aspects related to eating and meal choices. The rate of tooth loss was not definitively different based on past/current oral cGVHD status. Further efforts at mitigating the adverse impacts of oral cGVHD on nutrition and oral-health-related quality of life has the potential to improve the lives of alloHCT recipients.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC2.269 artigos no totalmostrando 199

2026

Serum vitamin d levels predict hospital-free days in outpatient allogeneic stem cell transplantation survivors: implications for long-term health outcomes.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
2026

Concerns regarding glomerular disease in chronic graft versus host disease (cGVHD).

Nefrologia
2026

Oral Squamous Cell Carcinoma Secondary to Chronic Graft-versus-host Disease: Report of Three Cases.

The Tokai journal of experimental and clinical medicine
2026

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia.

Pediatric blood &amp; cancer
2026

An evaluation of axatilimab for the treatment of chronic graft-versus-host disease.

Expert opinion on biological therapy
2026

Post-transplant Cyclophosphamide Reduces Bronchiolitis Obliterans Syndrome Risk Through Chronic Graft-versus-Host Disease Prevention: A Multicenter Cohort Study.

Chest
2026

[Research Progress on the Impact of Donor-Recipient Sex on Prognosis after Allogeneic Hematopoietic Stem Cell Transplantation --Review].

Zhongguo shi yan xue ye xue za zhi
2026

[Clinical Analysis of Allogeneic Hematopoietic Stem Cell Transplantation for Very Early-Onset Inflammatory Bowel Disease Caused by IL-10RA Mutation].

Zhongguo shi yan xue ye xue za zhi
2026

[Efficacy and safety of basiliximab in gastrointestinal chronic graft-versus-host disease].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi
2026

Ferritin as a pre-transplant biomarker for post-transplant outcomes in allogeneic stem cell transplantation using post-transplant cyclophosphamide.

Transplantation and cellular therapy
2026

Chronic graft versus host disease in upper limb: Calling upper limb rehabilitation specialists for improving outcomes in patients.

Clinical hematology international
2026

Early Marrow Microenvironment Immune Patterns After Hematopoietic Stem Cell Transplant in Pediatric Acute Lymphoblastic Leukemia Are Associated with Later Development of Chronic GvHD and Relapse.

International journal of molecular sciences
2026

Real-World Outcomes of Ruxolitinib as Salvage Therapy in Steroid-Refractory Acute and Chronic Graft-Versus-Host Disease: A Multicenter Retrospective Observational Study from Turkey.

Journal of clinical medicine
2026

Current Diagnosis and Management of Ocular Graft-Versus-Host Disease at a Tertiary Cancer Center.

Journal of clinical medicine
2026

Pleuroparenchymal Fibroelastosis Complicated by Pulmonary Alveolar Proteinosis After Peripheral Blood Stem Cell Transplantation.

Respirology case reports
2026

Neuromyelitis Optica Spectrum Disorder in a Pediatric Patient Following Haploidentical Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia.

Blood cell therapy
2026

Haematopoietic stem cell transplantation outcomes for teenage and young adult patients with acute leukaemia: A British Society of Blood and Marrow Transplantation and Cellular Therapy registry study.

British journal of haematology
2026

Rethinking Immune Checkpoint Inhibition in Cancer.

Scandinavian journal of immunology
2026

Tooth loss and oral health-related quality of life in a sub-cohort within the Chronic Graft-versus-Host Disease Consortium.

Transplantation and cellular therapy
2026

De novo and quiescent cGVHD are distinguishable in a prognostic biomarker panel.

Frontiers in immunology
2026

Chronic graft-versus-host disease: Current situation and unmet needs - A European position statement.

Bone marrow transplantation
2026

Effect of vitamin D replacement on nutritional status and muscle strength in patients after allogeneic stem cell transplantation and chronic graft-versus-host disease.

Clinical nutrition ESPEN
2026

Spanish real-world experience with belumosudil for chronic graft-versus-host disease after two or more prior lines of therapy.

Transplantation and cellular therapy
2026

Ruxolitinib as a Steroid-Sparing Treatment for Chronic Graft-Versus-Host Disease.

Transplantation and cellular therapy
2026

Neurological sequelae of chronic graft-versus-host disease: clinical spectrum and management considerations.

Internal medicine journal
2026

The efficacy and safety of MSCs in GVHD prevention and the treatment of SR-aGVHD: a systematic review and meta-analysis of randomized controlled trials.

Stem cell research &amp; therapy
2026

Haploidentical Hematopoietic Stem Cell Transplantation With Anti-Thymocyte Globulin in the Treatment of Older Adults With Hematological Malignancy.

EJHaem
2026

Evaluation of corneal epithelial thickness mapping via spectral-domain OCT in patients after allogeneic haematopoietic stem cell transplantation.

The British journal of ophthalmology
2026

Lymphocyte subset reconstitution and clinical outcomes following haploidentical hematopoietic stem cell transplantation.

British journal of cancer
2026

BET inhibition blunts antibody production and macrophage-mediated fibrosis to restore lung function in murine cGVHD.

Blood
2026

Bronchiolitis Obliterans Syndrome Following High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation in a Pediatric Patient With Neuroblastoma.

Cureus
2026

Chronic graft-versus-host disease suppressing CD56brightPerforinneg regulatory-like NK cells inhibit CD4+ T cells via PD-1, LAG-3, and TRAIL.

Cytotherapy
2026

Secondary Neoplasm in Survivors of Childhood Hematological Malignancies-Systematic Review.

Children (Basel, Switzerland)
2026

Optimizing Haploidentical Donor Selection for Pediatric Hematopoietic Cell Transplant.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
2026

Stem-like memory-T maintenance and differentiation into tissue-resident T cells sustain chronic graft-versus-host disease in mice.

Nature communications
2026

A Pilot Clinical Trial of a Group Coping Intervention for English and Spanish Speakers with Chronic Graft-Versus-Host Disease.

Research square
2026

Ruxolitinib in treatment-naive or corticosteroid-refractory pediatric patients with chronic graft-versus-host disease: final analysis of the phase 2 REACH5 trial.

Haematologica
2026

Real-world outcomes in refractory chronic graft-versus-host disease: the Italian multicenter experience with belumosudil.

Haematologica
2026

Avoidance of related donors in CAEBV with germline immune variants: long-termoutcome of matched unrelated donor HSCT - a case report.

Annals of hematology
2026

Longitudinal Study of Late Acute and Chronic Graft-Versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation: A Long-Term Follow-up Study from the Chronic Graft-Versus-Host Disease Consortium.

Transplantation and cellular therapy
2026

Inhibition of ROCK2 impedes osteoclastogenesis through Src-Ca2+-NFATc1 signaling pathway and alleviates ovariectomy-induced bone loss.

International immunopharmacology
2026

The BIOPREVENT machine-learning algorithm predicts chronic graft-versus-host disease and mortality risk using posttransplant biomarkers.

The Journal of clinical investigation
2026

Gastrointestinal-localized polymorphic post-transplant lymphoproliferative disorder following kidney transplantation after allogeneic hematopoietic stem cell transplantation: a rare case report.

Clinical journal of gastroenterology
2026

Proposal for Diagnostic Criteria for Manifestations of Chronic Graft-versus-Host Disease in Peripheral Nervous System and Muscles.

Transplantation and cellular therapy
2026

Chronic graft-versus-host disease has similar or worse impact on skin-specific quality of life than autoimmune connective tissue diseases: A cross-sectional study.

Journal of the American Academy of Dermatology
2026

Recent advances in the pathophysiology of acute and chronic graft-versus-host disease.

International journal of hematology
2026

Treosulfan/fludarabine versus thiotepa/busulfan/fludarabine for allogeneic haematopoietic cell transplantation in lymphoma in the post-transplant cyclophosphamide era: A GETH-TC study.

British journal of haematology
2026

Expanding the clinical spectrum of interleukin-2 receptor alpha chain deficiency: two novel cases with long-term hematopoietic stem cell transplantation outcome and literature review.

Frontiers in immunology
2026

Clinical Characteristics and Treatment Outcomes of Autoimmune-Like Hepatitis After Allogeneic Hematopoietic Stem Cell Transplantation.

Transplantation and cellular therapy
2026

Phagocytic Mesothelial Cells in Pericardial Effusion Following Allogeneic Peripheral Blood Stem Cell Transplantation for Chronic Active Epstein-Barr Virus Infection: A Distinctive Cytomorphological and Immunocytochemical Case Study.

Diagnostic cytopathology
2026

Phase I/II Trials of Donor Regulatory T Cells for the Treatment of Steroid-Refractory Chronic Graft versus Host Disease.

Blood advances
2026

Efficacy and safety of belumosudil for refractory chronic graft-versus-host disease in routine practice.

Annals of hematology
2025

A Case Report of HLA 5/10 Cord Blood Cell Engraftment in a Patient with Severe β Thalassemia after Haplo-Cord Stem Cell Transplantation.

Annals of clinical and laboratory science
2026

The outcomes of isoniazid prophylaxis in LTBI high-risk pediatric patients undergoing hematopoietic stem cell transplantation.

BMC infectious diseases
2026

Concurrent pulmonary aspergillosis and phaeohyphomycosis due to Verruconis spp. in a stem cell transplant recipient with chronic graft-versus-host disease.

Medical mycology case reports
2026

Severe brain atrophy after allogeneic hematopoietic stem cell transplantation in a patient suffering from chronic graft-versus-host disease.

Internal medicine (Tokyo, Japan)
2026

WITHDRAWN: Correction to Chronic graft-versus-host disease. Part II: Disease activity grading and therapeutic management [Journal of the American Academy of Dermatology 2024 Jan;90(1)19-36].

Journal of the American Academy of Dermatology
2026

WITHDRAWN: Correction to Chronic graft-versus-host disease. Part I: Epidemiology, pathogenesis, and clinical manifestations [Journal of the American Academy of Dermatology 2024 Jan;90(1)1-16].

Journal of the American Academy of Dermatology
2026

Novel R Shiny Tool for Survival Analysis With Time-Varying Covariate in Oncology Studies: Overcoming Biases and Enhancing Collaboration.

JCO clinical cancer informatics
2026

The Effect of Smoking and Pre-Allogeneic Hematopoietic Cell Transplant Pulmonary Comorbidity on the Incidence of Lung Graft-Versus-Host Disease and Post-Transplant Outcomes.

Cancers
2026

Mesenchymal Stem/Stromal Cells: A Review for Its Use After Allogeneic Hematopoietic Stem Cell Transplantation.

Biomolecules
2026

BTK Inhibition in Hematology: From CLL/SLL to Emerging Applications Across B-Cell and Immune Disorders.

Biomolecules
2026

Optimal Treatment of Steroid-refractory Chronic Graft-versus-host Disease (cGvHD) in the Era of Novel drugs - a Systematic Review and Meta-analysis.

Stem cell reviews and reports
2026

Bidirectional Interactions: Microbiome and Immune System Function in Cutaneous Graft-Versus-Host Disease.

Annals of plastic surgery
2026

Intensification of Treosulfan-Fludarabine Conditioning With Thiotepa Exhibited Effectiveness and Tolerability in Older or Comorbid Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant With Active Myeloid Neoplasm: A Real-world Study.

Transplantation direct
2026

Chronic graft-versus-host disease in the era of post-transplant cyclophosphamide.

Haematologica
2026

Real world experience using belumosudil for treatment of chronic graft versus host disease in children and young adults.

Bone marrow transplantation
2026

Chronic graft-versus-host disease in long-term survivors of childhood leukemia.

HemaSphere
2026

Bridging With Chimeric Antigen Receptor T-Cell Therapy or Chemotherapy to Allo-HSCT in B-ALL: A Comparison of Treatment Complications and Survival.

European journal of haematology
2026

Comparable outcomes of HSCT up-front and after failure of IST in pediatric aplastic anemia in recent years.

Blood advances
2026

Organ Responses, Survival, and Safety of Belumosudil in Chronic Graft-Versus-Host Disease: A Systematic Review and Meta-Analysis.

Clinical transplantation
2026

Autoimmune HLA alleles and neoantigens predict myelodysplastic syndrome outcomes after allogeneic HSCT: A CIBMTR analysis.

iScience
2026

Toward Better Response Assessment of Cutaneous Chronic Graft-Versus-Host Disease: A Report from the National Institutes of Health Consensus Project Task Force.

Transplantation and cellular therapy
2026

VULVO-Vaginal Chronic Graft-Versus-Host Disease Assessment: A Single-Center Prospective Observational Study.

European journal of haematology
2026

Chronic Graft-versus-Host Disease: A Review of Current Treatments beyond Second-Line and Emerging Therapies.

Acta haematologica
2026

Bruton tyrosine kinase inhibitors and invasive aspergillosis and mucormycosis: a case report and multi-center exploratory retrospective study.

ASM case reports
2025

[Prognostic Value of Dynamic Monitoring of WT1 Expression Levels for Relapse and Overall Survival in AML Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation During First Complete Remission].

Zhongguo shi yan xue ye xue za zhi
2025

Incidence, Risk Factors, and Treatment of Autoimmune Cytopenia Following Pediatric Allogeneic Hematopoietic Stem Cell Transplantation.

Journal of transplantation
2026

Long-Term Health Outcomes in Male Survivors of Childhood Cancer After Hematopoietic Stem Cell Transplantation: A Registry-Based Study.

Pediatric hematology and oncology
2025

Ruxolitinib Plus Extracorporeal Photopheresis for Steroid-Refractory Acute and Chronic Graft-Versus-Host Disease.

Journal of clinical medicine research
2025

Proposal for Diagnostic Criteria for Manifestations of Chronic Graft-versus-Host Disease in the Central Nervous System.

Transplantation and cellular therapy
2025

Ibrutinib oral suspension bioavailability and compatibility for optimal enteral administration route.

Therapeutic advances in hematology
2025

Detection and Management of Invasive Mold Disease in Pediatric Hematological Cancer Patients.

Infection and drug resistance
2025

The Effect of Chronic Graft-Versus-Host Disease and Its Therapy on Salivary Caries Risk Factors-An Exploratory Cross-Sectional Pilot Study.

Healthcare (Basel, Switzerland)
2025

Improving U-Net Segmentation of Cutaneous Chronic Graft-Versus-Host Disease in Clinical Photographs with Semi-Supervised Training.

Proceedings of SPIE--the International Society for Optical Engineering
2026

Intravenous immunoglobulin for cutaneous chronic graft-versus-host disease.

JAAD case reports
2025

Spatial Transcriptomics Analysis of Macrophage-to-Myofibroblast Transition in Bronchiolitis Obliterans Following Hematopoietic Stem Cell Transplantation.

Transplantation and cellular therapy
2026

Parvovirus B19 infection induces pure red cell aplasia after lung transplantation.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
2025

FDA Approves Axatilimab: A New Standard in Chronic Graft-Versus-Host Disease Therapy.

JPMA. The Journal of the Pakistan Medical Association
2026

Posttransplant cyclophosphamide in HLA-matched peripheral blood transplantation: what's next?

Blood
2025

Relationship between gammopathies, chronic graft-versus-host disease, and survival probability after allogeneic hematopoietic cell transplantation.

Polish archives of internal medicine
2026

Axatilimab Immunogenicity and Clinical Relevance in Patients with Chronic Graft-Versus-Host Disease.

Clinical pharmacology and therapeutics
2025

Real-World Effectiveness of Recombinant Zoster Vaccine in Allogeneic Hematopoietic Cell Transplant Recipients.

Transplantation and cellular therapy
2025

Higher HLA-DRB1 Evolutionary Divergence Is Associated with Reduced Relapse and Improved Survival after Matched Unrelated Hematopoietic Cell Transplantation.

Transplantation and cellular therapy
2026

Recombinant human soluble thrombomodulin prevents murine sclerodermatous chronic graft-versus-host disease.

Journal of immunology (Baltimore, Md. : 1950)
2026

Pre- and post-transplant extramedullary involvement in adult patients with t(8;21)(q22;q22) acute myeloid leukemia: incidence, risk factors and outcomes.

Leukemia &amp; lymphoma
2025

Feasibility of early tacrolimus initiation in haploidentical-PBSCT with post-transplant cyclophosphamide after melphalan-based conditioning regimen.

Blood cell therapy
2025

[Antibody-dependent pathogenesis and GVL induction mediated by DBY/HLA class II complex in chronic GVHD].

[Rinsho ketsueki] The Japanese journal of clinical hematology
2026

A Systematic Review of Treatments for Cutaneous Chronic Graft-versus-Host Disease.

Actas dermo-sifiliograficas
2025

[Methodological appraisal of statistical approaches to evaluating the impact of chronic graft-versus-host disease on mortality after hematopoietic stem cell transplantation].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi
2025

Model-based antithymocyte globulin dosing in ex vivo CD34+ selected allogeneic haematopoietic cell transplantation: a single-centre, single-arm, phase 2 study.

The Lancet. Haematology
2025

A Case of Secukinumab in the Treatment of Psoriasis-Like Cutaneous Chronic Graft-versus-Host Disease.

Case reports in dermatology
2025

Treosulfan-Based Conditioning Regimens for Allogeneic Hematopoietic Cell Transplantation in Acute Myeloid Leukemia and Other Myeloid Malignancies.

Pharmaceuticals (Basel, Switzerland)
2025

Cerebrospinal fluid profile associated with the incidence and outcomes of patients with chronic graft-versus-host disease after haploidentical hematopoietic stem cell transplantation.

Blood science (Baltimore, Md.)
2025

Symptoms of depression and anxiety in patients with transfusion-dependent thalassemia after hematopoietic stem cell transplantation: a single-center study.

Therapeutic advances in hematology
2025

Extracorporeal Photopheresis for Chronic Graft-Versus-Host Disease According to 2014 NIH Consensus Criteria.

Journal of clinical apheresis
2025

Ruxolitinib as second-line therapy for bronchiolitis obliterans syndrome after hematopoietic cell transplantation: a retrospective multicenter study.

Annals of hematology
2025

Can Posttransplant Cyclophosphamide Reduce the Risk of Graft-Versus-Host Disease for Pediatric Fully Matched Nonrelated Stem Cell Transplant?

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
2025

Advances in treatment of chronic graft-versus-host disease.

International journal of hematology
2025

Belumosudil for Chronic Graft-Versus-Host Disease: A Systematic Review and Meta-Analysis.

Transplantation and cellular therapy
2026

Current therapeutics for sclerotic and fibrotic manifestations of chronic graft-versus-host disease.

Bone marrow transplantation
2025

Linezolid-mediated Prevention of Fibroblast Activation and Tissue Fibrosis via Mitochondrial Translation Inhibition.

Arthritis &amp; rheumatology (Hoboken, N.J.)
2025

[Clinical Analysis of Cutaneous Chronic Graft-Versus-Host Disease Post-Allogeneic Hematopoietic Stem Cell Transplantation in Childhood].

Zhongguo shi yan xue ye xue za zhi
2026

Effect of Inflammatory Bowel Disease on Clinical Outcomes of Hematopoietic Cell Transplantation for Inborn Errors of Immunity.

Transplantation and cellular therapy
2025

Differential impact of graft-versus-host disease on post-transplant outcomes of chronic myelomonocytic leukemia according to transplant procedures.

Leukemia research
2026

Pulmonary Complications Following Hematopoietic Cell Transplantation in Patients with Myelofibrosis: A Single-Center Retrospective Cohort Analysis.

Transplantation and cellular therapy
2025

Toward Better and More Effective Clinical Trials for Chronic Graft-Versus-Host Disease.

Transplantation and cellular therapy
2026

Long-Term Follow-Up of the Baltimore Experience with Hematopoietic Cell Transplantation for Severe Aplastic Anemia Using Post-Transplantation Cyclophosphamide.

Transplantation and cellular therapy
2025

Effect of ruxolitinib on the oral mucosa in steroid-refractory graft-versus-host disease: a prospective observational exploratory study.

Clinical oral investigations
2026

Reproducibility and repeatability of the Myoton to quantify sclerotic chronic graft-versus-host disease.

Blood advances
2026

Controlling Renal Chronic Graft-Versus-Host Disease With a Belumosudil-Containing Regimen After Allogeneic Hematopoietic Stem Cell Transplantation: A Case Report.

Pediatric blood &amp; cancer
2025

Monoclonal and oligoclonal gammopathies secondary to allogeneic hematopoietic cell transplantation: a phenomenon associated with an increased survival and frequency of chronic graft-versus-host disease.

Polish archives of internal medicine
2025

Expansion of peripheral helper T cells in the peripheral blood of patients with chronic graft-versus-host disease.

Annals of hematology
2026

Long-term outcomes of αβ T-cell/CD19 B-cell-depleted peripheral blood stem cell transplantation from unrelated donors in pediatric and adolescent patients with severe aplastic anemia: a single-center study.

Cytotherapy
2025

Regulatory T-cell Activation Pathways in Patients With Chronic Graft-versus-host Disease Undergoing Extracorporeal Photopheresis Treatment: A Single-center Pilot Study.

In vivo (Athens, Greece)
2026

Opening New Horizons: Advanced Hematopoietic Stem Cell Expansion Strategies Bridging Cord Blood Therapy from Bench To Bedside.

Stem cell reviews and reports
2025

Non-Markov Nonparametric Estimation of Complex Multistate Outcomes After Hematopoietic Stem Cell Transplantation.

Biometrical journal. Biometrische Zeitschrift
2025

Monitoring for paediatric pulmonary graft versus host disease with multiple breath washout.

ERJ open research
2026

Salivary and Serum Cytokine Levels in Oral Chronic Graft-Versus-Host Disease: A Longitudinal Study on the Role of IL-6, IL-1α, and IL-17.

Journal of oral pathology &amp; medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
2026

Characterizing CYP3A4-mediated drug interactions: a fixed-sequence pharmacokinetic Chinese study of posaconazole and ruxolitinib in haematological malignancies.

The Journal of antimicrobial chemotherapy
2025

Pericardial effusion as a potential site of localized DNA virus reactivation following U-CB transplantation.

International journal of hematology
2026

Efficacy and Safety of Belumosudil in the Treatment of Refractory Chronic Graft-Versus-Host Disease.

Transplantation and cellular therapy
2025

Real-world Canadian data on belumosudil therapy in heavily pretreated patients with steroid-refractory chronic graft-versus-host disease: treatment outcomes and risk factor analysis for failure-free survival.

Annals of hematology
2025

[Thiotepa-containing conditioning for allogeneic hematopoietic stem cell transplantation in children with inborn errors of immunity: a retrospective clinical analysis].

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
2026

Impact of Obesity and Weight-Based Chemotherapy Dosing Adjustments on Outcomes of Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia.

Transplantation and cellular therapy
2025

Noninfectious Severe Pulmonary Complications in Immunocompromised Critically Ill Patients.

Seminars in respiratory and critical care medicine
2025

Cytogenetic risk-associated outcomes of antithymocyte globulin use in HLA-matched sibling transplantation for acute myeloid leukemia.

Annals of hematology
2025

[Strategies for the diagnosis and treatment of pulmonary chronic graft-versus-host disease after hematopoietic stem cell transplantation].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi
2025

[Effectiveness and safety of belumosudil in 20 patients with chronic graft-versus-host disease].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi
2025

Clinical profile and risk factors of low percent vital capacity after allogeneic hematopoietic stem cell transplantation.

Cytotherapy
2025

Reversible Bilateral Fixed Dilated Pupils in Hypercapnic Respiratory Failure Following Chronic Graft Versus Host Disease: A Case Report and Review of Literature.

Clinical case reports
2026

Transplantation in patients with lower-risk MDS: a prospective phase 2 trial based on donor availability.

Blood advances
2026

Distinct biological subtypes of chronic GVHD after pediatric hematopoietic cell transplantation.

Blood
2025

Kidney failure in the course of focal segmental glomerulonephritis in a patient after alloHSCT - a case study and review of the literature.

Journal of nephrology
2025

Allogeneic stem cell transplantation in chronic myelomonocytic leukemia: analysis of post-transplant survival and risk factors in 138 Mayo Clinic patients.

Blood cancer journal
2025

Quantifying the Clinical and Economic Burden of Graft-Versus-Host Disease Following Allogeneic Haematopoietic Stem Cell Transplantation in England: A Retrospective Cohort Study.

Advances in therapy
2025

Experience with second allogeneic hematopoietic stem cell transplantation in Chilean patients: A single-center study.

Hematology, transfusion and cell therapy
2025

Real-world experience of belumosudil and belumosudil/ruxolitinib combination in steroid-refractory chronic graft-versus-host disease.

Bone marrow transplantation
2025

ILT-2 and ILT-4 expression and donor genotype as factors associated with HSCT outcome.

Clinical immunology (Orlando, Fla.)
2025

Efficacy of ibrutinib and diagnostic liver biopsy for idiopathic refractory ascites after allogeneic stem cell transplantation.

International journal of hematology
2025

Sirolimus and Cyclosporine With Post-Transplant Cyclophosphamide or Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis in Unrelated Donor Hematopoietic Cell Transplantation.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
2025

Risk factors for bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation: a systematic review and meta-analysis.

BMC pulmonary medicine
2026

Identification of Distinct Subtypes in Immune Tolerance after Hematopoietic Cell Transplantation Using the Prospective ABLE1.0 Pediatric Study Cohort.

Transplantation and cellular therapy
2025

Development and Validation of an HPLC-MS/MS Method for Determining I-BET151 in Rat Plasma and Its application to Pharmacokinetic Studies.

Drug design, development and therapy
2025

Acetyl-CoA carboxylase 1 inhibition increases Treg metabolism and graft-versus-host disease treatment efficacy via mitochondrial fusion.

The Journal of clinical investigation
2025

Blood proteomics for quantitative biomarkers of cellular therapies.

Biomarker research
2026

Cytokines Induced by Antithymocyte Globulin in Transplantation Conditioning and Associated Infusional Side Effects.

Transplantation and cellular therapy
2025

Immunization Strategies in Pediatric Patients Receiving Hematopoietic Cell Transplantation (HCT) and Chimeric Antigen Receptor T-Cell (CAR-T) Therapy: Challenges and Insights from a Narrative Review.

Vaccines
2025

Corneal subbasal nerve alterations and tear cytokine associations in ocular chronic graft-versus-host disease.

Frontiers in medicine
2025

Exhausted-like effector CD8 T cells mediate immune-stromal interactions at mucosal Chronic Graft-versus-Host Disease onset.

bioRxiv : the preprint server for biology
2025

Prognostic Impact of the Level of Minimal Residual Disease Prior to Allogeneic Hematopoietic Stem Cell Transplantation on Pediatric Patients With Acute Lymphoblastic Leukemia: A 10-Year Single-Center Study.

Clinical lymphoma, myeloma &amp; leukemia
2026

Obesity Associations with Chronic Graft-Versus-Host Disease.

Transplantation and cellular therapy
2026

Toll-Like Receptor Polymorphisms Influence Graft-Versus-Host Disease and Infection Risk After Single-Unit Cord Blood Transplantation for Adults.

European journal of haematology
2025

Prolonged Hematogone Expansion Is Associated with Better Outcomes in Allogeneic Hematopoietic Stem Cell Transplantation Recipients.

Hematology reports
2025

[Ruxolitinib - Acute or chronic graft-versus-host disease after corticosteroid failure].

Bulletin du cancer
2025

Haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide in the public Chilean national health system: A single center study.

Hematology, transfusion and cell therapy
2026

Risk biomarkers of chronic GVHD in children aged 10 years or younger and children/adults older than 10 years.

Blood advances
2025

Sclerotic GVHD and scleroderma share dysregulated gene expression that is ameliorated by EREG therapeutic antibody.

Blood
2026

Efficacy and Safety of Allogeneic Hematopoietic Stem Cell Transplantation in Curing Sickle Cell Disease: A Systematic Review and Meta-Analysis of Single-Arm Studies.

Transplantation and cellular therapy
2025

Machine-Learning Predictive Tool for the Individualized Prediction of Outcomes of Hematopoietic Cell Transplantation for Sickle Cell Disease: Registry-Based Study.

JMIR AI
2025

ROCK 2 inhibition with belumosudil for the treatment of chronic graft-versus-host disease: a narrative review.

Therapeutic advances in hematology
2025

Veno-Occlusive Disease in Very Young Children: A Profile of High Morbidity With Low Mortality.

Pediatric blood &amp; cancer
2025

Approved and emerging therapies for glucocorticoid-refractory chronic graft-versus-host disease.

Current opinion in immunology
2025

Taiwan consensus on pulmonary chronic graft-versus-host disease: A joint statement from the Taiwan Society of Blood and Marrow Transplantation (TBMT) and Taiwan Society of Pulmonary and Critical Care Medicine (TSPCCM).

British journal of haematology
2025

Increased Plasma ST2 Levels Precede the Development of Severe Acute GvHD and Chronic GvHD After Pediatric Hematopoietic Stem Cell Transplantation.

Pediatric blood &amp; cancer
2025

Multiple Hematopoietic Stem Cell Transplantations in Pediatric Acute Myeloid Leukemia: Prognostic Significance of Remission and Severe Sinusoidal Obstruction Syndrome.

Pediatric blood &amp; cancer
2026

Dental plaque microbiota following allogeneic hematopoietic cell transplantation and risk of chronic graft-versus-host disease.

Haematologica
2025

[Effectiveness and safety of ibrutinib for steroid-dependent/refractory chronic graft-versus-host disease: a single-center analysis].

[Rinsho ketsueki] The Japanese journal of clinical hematology
2025

Extracorporeal photopheresis reduces the T cell stimulatory capacity of human primary blood conventional dendritic cells type 1.

Frontiers in immunology
2025

Successful repeated endoscopic balloon dilatation for esophageal stricture as chronic graft-versus-host disease.

Annals of hematology
2025

Comprehensive analysis of serum immune complexes identifies chronic graft-versus-host disease-associated antigenic molecules: A study by the Nagasaki transplant group.

Human immunology
2026

Efficacy and safety of belumosudil as compared with best available therapy for the treatment of cGVHD in the United States.

Blood advances
2025

Fecal microbiota transplantation for refractory chronic graft-versus-host disease after allogeneic hematopoietic cell transplantation: a pilot open-label, non-placebo-controlled study.

BMC medicine
2025

[Clinical analysis of hypomethylating agent in preventing relapse after allogeneic hematopoietic stem cell transplantation in high-risk acute myeloid leukemia].

Zhonghua er ke za zhi = Chinese journal of pediatrics
2025

STARComm Scalably Detects Emergent Modules of Spatial Cell-Cell Communication in Inflammation and Cancer.

bioRxiv : the preprint server for biology
2025

Chronic Graft-versus-Host disease trends over 30 years - a study by the EBMT transplant complications working party.

Bone marrow transplantation
2025

Neurological manifestations of chronic graft versus host disease.

Internal medicine journal
2025

First Report of Hematopoietic Stem Cell Transplantation for Children Diagnosed with Wiskott-Aldrich Syndrome in Vietnam.

Journal of blood medicine
2025

The Impact of Isolated HLA-DQB1 Mismatch and Donor Age in Unrelated Donor Hematopoietic Cell Transplantation with Post-Transplant Cyclophosphamide.

Transplantation and cellular therapy
2025

Bronchiectasis in Bronchiolitis Obliterans Syndrome after Hematopoietic Cell Transplantation.

Transplantation and cellular therapy
2025

Renal Involvement in Chronic Graft-Versus-Host Disease.

European journal of haematology
2025

New molecules in the therapy of chronic graft-versus-host disease.

Current opinion in hematology
2025

Voriconazole-induced periostitis in a child with finger pain and nodules: case report and literature review.

BMC musculoskeletal disorders
2025

Targeting hypoxia-inducible factor 1α in chronic graft-versus-host disease to enhance graft-versus-leukemia responses: implications for nanotherapeutics.

Frontiers in immunology
2025

Oral Verruciform Xanthoma as a Manifestation of Chronic Graft-Versus-Host Disease in Fanconi Anemia: A Rare Case Report.

Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
2025

[Therapeutic strategies for graft-versus-host disease in the new era].

[Rinsho ketsueki] The Japanese journal of clinical hematology
2025

Optimizing Timing and Preparation for Allogeneic Hematopoietic Stem Cell Transplantation in Higher-Risk Myelodysplastic Syndromes.

Blood and lymphatic cancer : targets and therapy
2025

Unveiling new horizons in severe aplastic anemia management: a two-decade study on intensive immunosuppressive therapy combined with unrelated cord blood efficacy.

Frontiers in immunology
2025

Cutaneous Chronic Graft-Versus-Host Disease.

Mayo Clinic proceedings
Ver todos os 2.269 no EuropePMC

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia.
    Pediatric blood &amp; cancer· 2026· PMID 41858074mais citado
  2. Ferritin as a pre-transplant biomarker for post-transplant outcomes in allogeneic stem cell transplantation using post-transplant cyclophosphamide.
    Transplantation and cellular therapy· 2026· PMID 41839367mais citado
  3. Early Marrow Microenvironment Immune Patterns After Hematopoietic Stem Cell Transplant in Pediatric Acute Lymphoblastic Leukemia Are Associated with Later Development of Chronic GvHD and Relapse.
    International journal of molecular sciences· 2026· PMID 41828562mais citado
  4. Neuromyelitis Optica Spectrum Disorder in a Pediatric Patient Following Haploidentical Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia.
    Blood cell therapy· 2026· PMID 41815182mais citado
  5. Tooth loss and oral health-related quality of life in a sub-cohort within the Chronic Graft-versus-Host Disease Consortium.
    Transplantation and cellular therapy· 2026· PMID 41802602mais citado
  6. [The influence of different collagenases on the analysis of immune cells in salivary glands of mice with chronic graft-versus-host disease].
    Zhonghua Xue Ye Xue Za Zhi· 2026· PMID 41991311recente
  7. Individualized decitabine dosing for post-HSCT maintenance in MDS and secondary AML from MDS: long-term outcomes from the PODAC trial and matched controls.
    Ther Adv Hematol· 2026· PMID 41987809recente
  8. Chronic graft-versus-host disease after haploidentical transplantation in aplastic anemia: clinical characteristics, risk factors, and survival outcomes.
    Bone Marrow Transplant· 2026· PMID 41975072recente
  9. The Impact of Post-Transplant Interventions and Chronic GVHD on Survival in Myeloid Malignancies Harboring TP53 Alterations.
    Transplant Cell Ther· 2026· PMID 41974306recente
  10. [Allogeneic hematopoietic stem cell transplantation in children's acute myeloblastic leukemia: Survival and relapse].
    Tunis Med· 2025· PMID 41949966recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:99921(Orphanet)
  2. MONDO:0020547(MONDO)
  3. GARD:10964(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Q111329725(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

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Doença enxerto versus hospedeiro, crônica
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