Encefalite autoimune

Plasma Exchange in Pediatric Autoimmune Encephalitis

NCT07707739

A Study in Participants With Anti-NMDAR Encephalitis and Anti-NMDAR Autoantibody-Associated Psychiatric Disease

NCT07093333

Safety and Pharmacodynamics of QH103 Cell Injection in the Treatment of Patients With Relapsed/Refractory Antibody-Mediated Neurological Autoimmune Diseases.

NCT07526493

Is [18F]-DPA-714 PET a Good Marker of Neuroinflammation in Autoimmune Encephalitis?

NCT07488117

CD19/BCMA-Targeted UCAR-T for Patients With Neurological Autoimmune Diseases

NCT07337785

NCT07707739 · Plasma Exchange in Pediatric Autoimmune EncephalitisRecrutando

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NA🇪🇬 Egito

NCT07093333 · A Study in Participants With Anti-NMDAR Encephalitis and Ant…Recrutando

PHASE2South Korea

NCT07526493 · Safety and Pharmacodynamics of QH103 Cell Injection in the T…Recrutando

PHASE1🇨🇳 China

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70 ensaios clínicos encontrados, 36 ativos.

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Ver todos no ClinicalTrials.gov

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Publicações mais relevantes

Timeline de publicações

3.812 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 3.812

#1

Fixel-Based Analysis of Pretreatment MRI Identifies White Matter Abnormalities in Pediatric Anti-NMDAR Encephalitis.

Journal of child neurology2026 Mar 25

Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is an autoimmune disorder in which conventional MRI often appears normal, leading to clinical-radiologic dissociation and hindering early diagnosis and monitoring. We retrospectively studied five pediatric patients with anti-NMDAR encephalitis and compared their pretreatment diffusion MRI to age- and sex-matched controls. Using fixel-based analysis (FBA), we quantified tract-specific white matter abnormalities at the individual level. All patients showed significantly reduced fiber density and cross-section, with patterns ranging from focal to widespread involvement. In two patients, FBA abnormalities corresponded to seizure lateralization on EEG despite normal MRI, emphasizing FBA's added value in detecting seizure-concordant injury. One patient, exhibiting the highest disease burden and marked CSF pleocytosis, demonstrated extensive white matter tract disruption. These findings indicate that FBA derived from pretreatment MRI can identify clinically significant white matter injury at disease onset in pediatric anti-NMDAR encephalitis. Future large-scale studies should explore its potential as an individualized biomarker, which may offer diagnostic and prognostic value beyond conventional imaging.

#2

[18F]Fluorodeprenyl-D2 PET as a Tool to Monitor Disease Activity in GAD65-Ab Autoimmune Encephalitis.

Annals of clinical and translational neurology2026 Mar 24

To evaluate [18F]fluorodeprenyl-D2 ([18F]F-DED) positron-emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. [18F]F-DED PET was performed in 25 GAD65-AIE patients and 8 controls using dynamic (0-60 min) and static (30-60 min) acquisitions. Global astrogliosis was assessed by volumes of distribution (VT; 1-tissue-compartment model with carotid input) and standardized uptake values (SUV). Regional cerebellar and mesiotemporal (MT) uptake was normalized to global uptake (SUVr). PET measures were correlated with clinical phenotypes, MRI findings, and serum biomarkers (neurofilament light chain [sNfL], GAD65-Ab titers, and glial fibrillary acidic protein [sGFAP]). Clinical phenotypes included limbic encephalitis/temporal lobe epilepsy (LE/TLE; n = 17), stiff-person syndrome (n = 4), and cerebellar ataxia (CA; n = 4), with overlap in nine patients. Global [18F]F-DED uptake was higher in patients than controls. VT analysis showed increased cortical and MT uptake, while SUVr analysis demonstrated elevated MT uptake across the cohort. LE/TLE patients exhibited increased MT uptake, and CA patients showed higher cerebellar uptake. [18F]F-DED uptake did not correlate with sNfL or GAD65-Ab titers, but sGFAP showed associations with cerebellar and white-matter uptake. Regional uptake correlated with clinical severity in LE/TLE (MT lobe) and CA (cerebellar white matter). [18F]F-DED PET reveals region-specific astrogliosis corresponding to clinical manifestations and disease severity in GAD65-AIE, supporting its potential as a monitoring tool for disease activity.

#3

Population-Based Epidemiology of Autoimmune Seizures and Epilepsies.

Annals of neurology2026 Mar 24

To estimate the prevalence, incidence, and disease burden of autoimmune seizures and epilepsies in Olmsted County. We conducted a retrospective, population-based study using the Rochester Epidemiology Project (1996-2019). Age- and sex-standardized rates (2019 United States standard population) per 100,000 were calculated with 95% confidence intervals (95% CIs). Temporal trends in incidence were assessed over 3 consecutive 8-year intervals (1996-2003, 2004-2011, and 2012-2019) using Poisson regression to estimate rate ratios per period and trend. Disability-adjusted life years (DALYs), years of life lost (YLL), and years lived with disability (YLD) and 95% uncertainty intervals (95% UIs) were estimated for 2019. Twenty-three patients were identified between 1996 and 2019. In 2019, the standardized prevalence of all autoimmune seizures and epilepsies was 9.81 (95% CI, 5.59-15.21) per 100,000, including autoimmune-associated epilepsy (AAE) 7.27 (3.74-11.95) and acute symptomatic seizures secondary to autoimmune encephalitis (ASSAE) 2.55 (0.69-5.60). From 1996 to 2019, the standardized incidence was 0.50 (0.29-0.77) per 100,000 person-years overall, with AAE 0.36 (0.19-0.59) and ASSAE 0.15 (0.05-0.30). By period, the standardized incidence of all autoimmune seizures and epilepsies suggested a rising trend from 0.28 (95% CI, 0.06-0.68) in 1996 to 2003 to 0.60 (95% CI, 0.24-1.12) in 2004-2011, then plateaued at 0.53 (95% CI, 0.21-1.00) in 2012 to 2019 (rate ratio per 8-year interval 1.30, 95% CI, 0.71-2.38), largely driven by the seropositive subgroup. The standardized DALY rate was 26.27 (95% Uncertainly intervals [UI], 5.30-67.09) per 100,000 (YLL 20.07 [0.00-60.21] and YLD 6.20 [5.06-7.39]). Although autoimmune seizures and epilepsies remain rare, they result in a disproportionately high disease burden. ANN NEUROL 2026.

#4

Central nervous system pericytes express soluble ST2 in inflammation and injury.

Molecular brain2026 Mar 19

Brain pericytes are mediators of neuroinflammation, as evidenced in vitro, in animal models and humans. We and others have identified the platelet-derived growth factor (PDGF)-BB -PDGF receptor beta (PDGFRB) pathway as a key modulator of inflammatory cues in human brain pericytes. We investigate the receptor for interkeukin-33 (IL-33), interkeukin-1 receptor-like 1 (IL1RL1; also known as ST2) as a highly upregulated transcript in response to PDGF-BB stimulation in pericyte cultures. We show that pericytes express transcripts for both the membrane bound form of the receptor (ST2L) and the soluble form (sST2) that acts as a decoy and blocks IL-33 signalling. Human brain pericytes secrete sST2 in response to PDGF-BB, but also to transforming growth factor alpha (TGF) alpha and interleukin-4 (IL-4), although they are unresponsive to IL-33 treatment. We also examine pericyte expression of both IL1RL1 transcripts using RNAscope in two different in vivo models of neuroinflammation, experimental autoimmune encephalitis (EAE) and photothrombotic stroke. We present data showing that in rodents pericytes increase transcript expression predominantly for soluble IL1RL1 in inflammatory and stroke models. Our results highlight a novel expression pattern of the soluble and membrane bound forms of the IL-33 receptor in vitro and in combination with our observations in vivo suggest that cerebrovascular pericytes may negatively regulate IL-33 signalling following injury or inflammatory insults to the brain.

#5

Clinical profile and treatment outcomes of patients with chronic presentations of autoimmune encephalitis: expanding the spectrum.

BMJ neurology open2026

The spectrum of autoimmune encephalitis (AIE) is evolving due to heterogeneity of clinical syndromes associated with autoantibodies. While majority of patients present within 3 months, little is known about chronic presentations of AIE. This study aims to characterise the neurobehavioural profile and assess the long-term outcomes of patients with chronic presentations of AIE. Patients with serum or cerebrospinal fluid AIE antibody positivity were included in the study. We reviewed their clinical, cognitive, imaging and treatment characteristics as well as their long-term outcomes. Addenbrooke's Cognitive Examination-III and Clinical Dementia Rating score were used to evaluate global cognition and the severity of dementia, respectively. Of 306 patients diagnosed with dementia in a cognitive disorders' clinic, 28 had chronic presentations of AIE. The mean age of 28 patients was 55 years (range: 50-60), and mean duration of illness was 12 months (range: 3-84). Of the 28 patients, 9 (32%) were positive for leucine-rich glioma inactivated 1 antibody, 7 (25%) anti-thyroid peroxidase, 5 (18%) N-Methyl D-Aspartate receptor, 5 (18%) glutamic acid decarboxylase 65 and 2 (7%) had contactin-associated protein antibodies. Memory, language and behavioural disturbances with prominent neuropsychiatric symptoms were characteristic clinical manifestations. The course was chronic progressive, relapsing and rapidly progressive in 18 (64%), 8 (28%) and 2 (7%) patients, respectively. On immunomodulator therapy, the majority (21/28) improved, while 7/28 patients remained unchanged or experienced an exacerbation of symptoms. Chronic presentations of AIE are less known, and often misdiagnosed due to insidious progressive course and resemble degenerative dementias. A high index of suspicion in patients with chronic atypical cognitive syndromes and a low threshold for antibody testing will allow for prompt diagnosis, appropriate immunotherapy and improvement in clinical outcome.

Publicações recentes

Intraventricular hemorrhage, suspected EBV reactivation, and TBA-positive epilepsy after deep cervical lymphovenous anastomosis in Alzheimer's disease: a case report.

Front Aging Neurosci2026

HLA genotyping and clinical characteristics of early-onset and late-onset anti-LGI1 encephalitis: a single-center cohort study in China.

Front Immunol2026

Fatal Rapidly Progressive Encephalopathy Mimicking Depression: A Diagnostic Dilemma of Suspected Seronegative Autoimmune Encephalitis.

Cureus2026 Mar

Autoimmune Encephalitis Associated with Anti-titin Antibodies following Immune Checkpoint Inhibitor Therapy: A Case Report.

Intern Med2026 Apr 14

Anti-NMDAR encephalitis in a patient with possible IgG4-related hypertrophic pachymeningitis: a case report.

Virchows Arch2026 Apr 15

Ver todas no PubMed

📚 EuropePMC1.552 artigos no totalmostrando 199

Journal of child neurology

Fixel-Based Analysis of Pretreatment MRI Identifies White Matter Abnormalities in Pediatric Anti-NMDAR Encephalitis.

[18F]Fluorodeprenyl-D2 PET as a Tool to Monitor Disease Activity in GAD65-Ab Autoimmune Encephalitis.

Population-Based Epidemiology of Autoimmune Seizures and Epilepsies.

Annals of neurology

Sporadic Creutzfeldt-Jakob Disease With Spinal Cord Lesions: A Case Report.

Case Report: Dual response to efgartigimod in myasthenia gravis and comorbid autoimmune disorders: a case series.

Journal of the Academy of Consultation-Liaison Psychiatry

Recommendations for a Pediatric Catatonia Clinical Pathway in Acute Medical Care Settings: A Delphi Consensus Study.

Single-institution experience with efgartigimod in patients with GFAP astrocytopathy: Treatment response and adverse events.

Therapeutic perspectives in refractory anti-NMDA receptor encephalitis.

The Lancet. Neurology

The primary care companion for CNS disorders

An Atypical Presentation of Autoimmune Encephalitis.

Anti-NMDA receptor encephalitis in the setting of inherited chromosomally integrated human herpesvirus 6B (iciHHV-6B): A case report.

IDCases

Neuropsychopharmacology reports

Combination Versus Monotherapy in Acute Anti-LGI1 Encephalitis: A Real-World Dose Optimization Analysis.

Central nervous system pericytes express soluble ST2 in inflammation and injury.

Molecular brain

Clinical profile and treatment outcomes of patients with chronic presentations of autoimmune encephalitis: expanding the spectrum.

Brain imaging and behavior

Acute cerebral blood flow and its connectivity in patients with anti-LGI1 autoimmune encephalitis: an arterial spin labeling study.

Vital Prognosis and Causes of Death in Adults with Encephalitis.

Neurocritical care

International journal of surgery case reports

Refractory anti-NMDA receptor encephalitis driven by a contralateral ovarian teratoma following unilateral oophorectomy: a case report.

Therapeutic advances in neurological disorders

Testing for neural antibodies in autoimmune encephalitis: who, what, where, when, why, and how.

Pediatric anti-NMDAR encephalitis: Neuroradiological presentation, cognitive outcome and volumetric MRI analysis.

NeuroImage. Clinical

Characterising executive functioning in the chronic phase of autoimmune encephalitis: A study by the Australian autoimmune encephalitis consortium.

Visual Disturbance and Elevated Glutamic Acid Decarboxylase Antibody Levels as Manifestations of Central Nervous System Lymphoma.

Neurology India

Alternative diagnoses of suspected paraneoplastic neurological syndromes: a population-based study.

The Treatment of Antibody-Mediated Encephalitis: Current, Future Therapies, Unmet Need and Patient Management.

Advances in therapy

International medical case reports journal

Morvan Syndrome Masquerading as Anxiety Disorder: A Case Report Highlighting the Importance of Recognizing Organic Signs in Psychiatric Settings.

Journal of translational autoimmunity

Intrathecal immunoglobulin production in the diagnosis, prognosis, and monitoring of autoimmune diseases of the central nervous system.

Neuropsychiatric Presentation of Non-paraneoplastic Voltage-Gated Calcium Channel Autoimmune Encephalitis: A Case Report.

European journal of medical research

Clinical features, prognosis, and influencing factors of relapse in autoimmune encephalitis associated with antibodies against cell surface antigens: a single-center retrospective study.

Morvan syndrome associated with prominent Tau pathology: A clinicopathological case report.

Non-invasive Assessment of Glymphatic System Function in Patients with Anti-LGI1 Encephalitis.

Harvard review of psychiatry

Anti-GAD65 Encephalitis: A Cryptic Case Requiring a Multidisciplinary Approach.

Antibody-Negative Nivolumab-Induced Autoimmune Encephalitis: A Case Report and Review of Seronegative Presentations.

The European respiratory journal

Severe sleep-related hypoventilation in antibody-positive and antibody-negative autoimmune encephalitis: an emergency.

Minimally Clinically Important Difference of the Clinical Assessment Scale in Autoimmune Encephalitis.

Successful fresh formulation CD19 CAR-T cell therapy for GAD65 antibody-mediated cerebellar ataxia. A Case Report.

Revista medica del Instituto Mexicano del Seguro Social

[Cognitive and psychiatric evolution in autoimmune encephalitis in a school-aged child: Clinical case].

Deciphering Involuntary Movements: A Case of Seronegative Autoimmune Encephalitis With a Kaleidoscopic Presentation.

Annals of Indian Academy of Neurology

Headache in a Patient with Anti-Leucine-Rich Glioma Inactivated 1 Autoimmune Encephalitis Responding to Rituximab.

The journal of prevention of Alzheimer's disease

Neuronal autoantibodies in neurodegenerative dementia: From evidence to clinical framework.

Machine learning model predicts prognosis in SARS-CoV-2-infected autoimmune encephalitis patients.

Rethinking rituximab in neuroimmunology: Real-world efficacy, cost-effectiveness, and long-term remission.

Journal of translational autoimmunity

Anti-IgLON5 encephalitis is associated with anti-retinal immunological reactivity without retinal alteration.

CAR T-Cell Immunotherapy in Neuroautoimmune Diseases: Focus on the Central Nervous System.

Biomedicines

Clinical features and outcomes of anti-NMDAR autoimmune-related central nervous system involvement in patients with teratoma: a retrospective cohort study.

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego

Rare demyelinating diseases of the central nervous system: A diagnostic and therapeutic challenge - based on the case of a young woman with MOGAD.

Case Report: Thymoma-associated myasthenia gravis, myositis, myocarditis, and anti-GAD65 autoimmune encephalitis: a unique case of paraneoplastic polyautoimmunity.

Seronegative Autoimmune Encephalitis With Neuropsychiatric Presentation: A Case Report.

Autoimmune Encephalitis Associated With Anti-Contactin-Associated Protein-Like 2 (Anti-CASPR2) Antibodies in an Elderly Patient: A Case Report.

Current opinion in neurology

Update on pediatric autoimmune encephalitis-associated epilepsy.

Pembrolizumab-Induced Autoimmune Encephalitis: A Rare Case.

New microbes and new infections

A rare case of breakthrough tick-borne encephalitis in early adolescence after vaccination with four doses of TBE vaccine.

A qualitative exploration of patient experiences living with autoimmune encephalitis.

Scientific reports

A Systematic Review and Meta-Analysis of the Recurrence of Autoimmune Encephalitis.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Reversible bilateral striatal lesions in NPSLE.

C-reactive protein-to-albumin ratio predicts intensive care admission and disease severity in autoimmune encephalitis.

Clinical response to therapeutic plasma exchange in patients with immune-mediated inflammatory diseases of the central nervous system.

Anales de pediatria

Journal of child neurology

Delayed-Onset Acute Chorea Following Anesthesia.

Beyond Autoimmune Encephalitis-Insights and Cross-Disciplinary Lessons.

JAMA neurology

Lentiform fork sign mimicking uremic encephalopathy in an atypical case of autoimmune limbic encephalitis.

Radiology case reports

Case Report: Anti-neural cell adhesion molecule 1 antibody-positive encephalitis presenting with schizophrenia-like symptoms and an ovarian teratoma.

Rinsho shinkeigaku = Clinical neurology

[A case of autoantibody-negative autoimmune encephalitis associated with mature ovarian teratoma, successfully treated with early ovariectomy].

Anti-GABA-AR encephalitis or neuropsychiatric SLE? Avoiding misdiagnosis through comprehensive antibody testing beyond commercial panels.

Practical neurology

Reduced Hospital Incidence of Autoimmune Encephalitis During the COVID-19 Pandemic.

FDG-PET Associations With Disease Severity and Outcomes in NMDA-Receptor IgG Autoimmune Encephalitis.

Journal of clinical medicine

Soluble TREM2 Is Elevated in Pediatric Patients with Anti-NMDAR Encephalitis.

Diagnostics (Basel, Switzerland)

Abnormal Magnetic Resonance Imaging Patterns in Patients with Neuropsychiatric Disorders Due to Anti-NMDA Receptor Encephalitis: A Comparative Study.

Disease models of anti-N-methyl-d-aspartate receptor encephalitis: Investigating pathogenesis and targeted therapy.

Experimental neurology

Pediatric new-onset super refractory status epilepticus: Potential of timely immunotherapy in a resource-limited PICU.

Seizure

Infection-triggered encephalopathy syndrome in children: a neuroimaging perspective.

Pediatric radiology

Frontiers in neuroscience

Case Report: Progressive myoclonus epilepsy as an early manifestation of neuronopathic Gaucher disease.

Clinical practice and cases in emergency medicine

Case Report: Pediatric Hallucinations and Anti-Neuronal Intermediate Filament Autoimmune Encephalitis.

Neurological research and practice

Consider autoimmune encephalitis in cases of headache, dizziness, and mild pleocytosis following SARS-CoV-2 infection.

Journal of medical case reports

Autoimmune encephalitis associated with anti-recoverin antibodies.

Anti-gad autoimmune encephalitis: a case report.

Comparative Effectiveness of Brivaracetam, Cenobamate, Lacosamide, and Perampanel in Focal Epilepsy.

JAMA neurology

Cellular and molecular neurobiology

CSF Leukocytes in Intracranial Infections: Diagnostic, Mechanistic, and Therapeutic Insights for Neurocritical Care.

Brain imaging reveals hierarchical topology changes and stage-dependent impairments in autoimmune encephalitis.

Characteristics of and risk factors for epilepsy after autoimmune and infectious encephalitis.

Simultaneous perfusion and dopaminergic imaging using dual-isotope CZT SPECT/CT in dementia with Lewy bodies.

EJNMMI research

Journal of the neurological sciences

Long-term cognitive outcomes and persistent executive dysfunction in LGI1 autoimmune encephalitis.

Immune checkpoint inhibitor-induced AMPA2 antibody-positive encephalitis: a case report.

Frontiers in oncology

Case Report: Recurrent anti-glutamic acid decarboxylase 65 antibody-associated encephalitis in a child.

Systemic and organ-specific autoantibodies and worse outcomes in autoimmune encephalitis: a multicenter cohort study.

Adolescent autoimmune encephalitis with dual positive anti-Drebrin and anti-mGluR2 antibodies: a case report.

CASPR2 antibody-related neurological syndromes in children: three cases report and literature review.

BMC pediatrics

A patient with anti-IgLON5 disease associated with cerebral hemorrhage, multiple ischemic strokes, and kidney failure: case report.

Rinsho shinkeigaku = Clinical neurology

[A case of anti-leucine-rich glioma inactivated protein 1 (LGI1) antibody-positive autoimmune encephalitis with electrographic seizures without epileptic seizure symptoms].

Paraneoplastic Encephalitis Unmasking Small-Cell Lung Cancer With Impending Superior Vena Cava Obstruction: A Case Report.

European journal of immunology

Microbial-Immune Interplay in CNS Autoimmune Diseases: Lessons from Animal Models and Clinical Studies.

Anti-AMPAR limbic encephalitis as the initial presentation of metastatic small cell cancer.

BMJ case reports

Autoimmune encephalitis associated with antibodies against intracellular antigens in children.

Clinical neurology and neurosurgery

Anti-LGI-1 autoimmune encephalitis: Insights from literature and a very late-onset case report.

Autoimmune-associated epilepsy or acute symptomatic seizures? A case series of recurrent seizures in patients with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).

Epilepsy research

Stroke-Like Migraine Attacks After Radiation Therapy (SMART) Syndrome: A Case Report and Review of a Rare Delayed Complication of Cranial Irradiation.

Clinical case reports

Diagnostic biomarkers for differentiating AQP4-IgG- negative NMOSD from other nervous system autoimmune disorders: a retrospective study.

Anti-NMDA receptor encephalitis unmasking Sjögren's disease: a case report and literature review.

Diagnostics (Basel, Switzerland)

Clinical Phenotypes and Prognosis of Anti-mGluR1 Encephalitis: A Single-Center Case Series and Comprehensive Literature Review.

Seizure burden and treatment efficacy evaluation in anti-LGI1 autoimmune encephalitis patients using wearable device: a pilot feasibility study.

Frontiers in human neuroscience

Impact of sex differences on clinical characteristics of anti-N-methyl-D-aspartate receptor encephalitis during the acute phase: a single-center retrospective study.

Anti-mGluR encephalitis: case series and literature review.

Clinical, imaging, and immunological features of GFAP astrocytopathy: a systematic review with regional comparison.

Neuroinflammation in GAD65 Antibody-Associated Epilepsy Measured Using [18F]DPA-714 PET/MRI.

CNS neuroscience & therapeutics

Mimics and Diagnostic Pitfalls of Anti-Adenylate Kinase 5 Limbic Encephalitis.

Infection as a potential trigger in glial fibrillary acidic protein astrocytopathy: a case report and review of immunotherapeutic strategies.

TMEM132A autoimmunity in patients with suspected autoimmune cerebellar ataxia.

Antibodies (Basel, Switzerland)

Paraneoplastic Neurological Syndromes: Advances and Future Perspectives in Immunopathogenesis and Management.

New-onset refractory status epilepticus associated with Sjögren's disease.

Clinical decision-making in relation to autoimmunity: insights from catatonia and autoimmune encephalitis.

BJPsych open

Screening for neuronal antibodies in cognitive impairment and dementia clinics: a prospective multicenter study.

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego

Autoimmune encephalitis with LGI1 antibodies: a report of two cases.

Journal of central nervous system disease

Racial and Ethnic Disparities in Clinical Characteristics and Outcomes in Adults With Encephalitis: A Retrospective Study.

American journal of translational research

Efficacy and safety of blood purification in the treatment of autoimmune encephalitis: a meta-analysis.

Brain : a journal of neurology

Brainstem pathology in anti-IgLON5 disease: new insights into early events and tau progression.

Cryo-EM of autoantibody-bound NMDA receptors reveals antigenic hotspots in an active immunization model of anti-NMDAR encephalitis.

Science advances

Inflammation research : official journal of the European Histamine Research Society ... [et al.]

Machine learning and multi-omics integration identifies immunological predictors and mechanistic insights in autoimmune encephalitis.

Journal of neuroinflammation

Methylglyoxal-modification of NLRP3 interrupts NLRP3-NEK7 interaction diminishing inflammasome activation and neuroinflammation.

Role of B cells and pathogenic autoantibodies in autoimmune CNS and PNS neurologic diseases.

Immunotherapies on autoimmune encephalitis.

Autoimmune encephalitis, autoimmune dementias, and autoimmune psychotic disorders.

The evolution and current status of anti-B-cell therapies in autoimmune neurologic diseases.

Rapidly progressive sensorineural hearing loss due to sporadic Creutzfeldt-Jakob disease.

BMJ case reports

Clinica chimica acta; international journal of clinical chemistry

Optimized NMDAR autoantibody detection via combined NR1-4a LCBA and NR1/NR2 fusion FCBA.

The Gut Feeling Behind Autoimmune Encephalitis.

Epilepsy currents

Case Report: Creutzfeldt-Jakob disease and diagnosis challenges: case report and evidence synthesis.

F1000Research

Brain and neural cell type proteomics reveal extracellular matrix proteins enriched in progressive multiple sclerosis.

Nature communications

Systematic Review and Meta-Analysis of the Clinical Features Associated With Seronegative Autoimmune Encephalitis.

Relative Frequency and Distinctive Features of Anti-Ma2 Nonparaneoplastic Neurologic Disorders: A French Cohort Study.

Autoimmune Glial Fibrillary Acidic Protein (GFAP) Astrocytopathy Presenting as Viral Encephalitis: A Case Report and Literature Review.

Aseptic Meningitis and Papillary Edema: Uncommon Presentation of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD).

Three Challenging Cases of Autoimmune Encephalitis: A Case-Series and a Review of the Literature.

Clinical case reports

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

The spectrum of movement disorders in neurosyphilis: A systematic review.

The First Case of Bacillus Calmette-Guérin-Induced Autoimmune Encephalitis.

IJU case reports

Journal of child neurology

Multivariate Risk-Factor Analysis of Short-Term Poor Prognosis in Children With Autoimmune Encephalitis.

The Lancet regional health. Europe

Development and validation of the NEOS2 score for prediction of long-term outcomes and improvement after first-line immunotherapy in patients with anti-NMDAR encephalitis: an international cohort study.

Autoimmune Encephalitis in Pregnancy: A Case Report.

Trapped in Silence: Severe Catatonia From Anti-N-Methyl-D-Aspartate (NMDA) Receptor Encephalitis in a Neurofibromatosis Type 1 Patient With Craniopharyngioma.

Encephalitis (Seoul, Korea)

Fatal retroperitoneal hemorrhage following enoxaparin administration in a patient with autoimmune encephalitis: a case report.

IL6 blockade: an effective approach in steroid-refractory immune checkpoint inhibitor-related neuropathies requiring ICI rechallenge-case report.

ESMO open

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Deciphering autoimmune encephalitis: Immune mechanisms, therapeutic paradigms, and global research trends.

Case reports in psychiatry

Autoimmune Psychosis Exists: Early Diagnosis of an Anti-NMDA Receptor Autoimmune Encephalitis Presenting as First-Episode Psychosis in a 25-Year-Old Male-A Case Report.

Open forum infectious diseases

Evaluating the Clinical Impact of Metagenomic Next-Generation Sequencing in CNS Infections: A Diagnostic Pathway and Resource Utilization Modeling Study.

Anti-LGI1 encephalitis: clinical presentation, imaging features, and prognostic analysis.

Frontiers in neurology

Predicting epilepsy after new onset refractory status epilepticus due to autoimmune encephalitis: The DAME score.

Epilepsia

Efgartigimod for Generalized Myasthenia Gravis and Beyond: A Narrative Review of Its Pharmacological Profile, Clinical Utility, and Expanding Applications.

Biomedicines

Immature ovarian teratomas in anti-NMDA receptor encephalitis.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Early psychiatric manifestations in pediatric autoimmune encephalitis: clinical data from a tertiary center.

Journal of intensive care medicine

Rituximab in the Intensive Care Unit: A Review of Indications and Clinical Considerations.

Progress in the preparation of an active immunization model of anti-N-methyl-D-aspartate receptor encephalitis in animals.

Progressive Supranuclear Palsy With Post-traumatic Frontal Lobe Damage Mimicking Anti-IgLON5 Antibody Disease.

Rare Variants of Immune-Related Genes Increase Susceptibility to Autoimmune Encephalitis: An Association Study.

Neurology international

Anti-AMPA receptor limbic encephalitis as the initial manifestation of metastatic breast cancer.

BMJ case reports

Cardiac involvement in anti-GABA-B receptor encephalitis: a case report.

International ophthalmology clinics

Comprehensive Review on the Neuro-ophthalmic Manifestations of Autoimmune Encephalitis Syndromes.

Beyond the Psychiatric Lens: Difficulties in Diagnosing Anti-N-Methyl-D-Aspartate Receptor Encephalitis With Psychiatric Presentation.

Coexistence of anti-neurexin-3α-associated autoimmune encephalitis and systemic lupus erythematosus in an adult patient: a case report.

Drug design, development and therapy

Double Filtration Plasmapheresis Shows Superior Short-Term Efficacy to Intravenous Methylprednisolone in Acute Autoimmune Encephalitis: A Prospective Observational Study.

Indian journal of sexually transmitted diseases and AIDS

A rare presentation of herpes simplex virus type 2 encephalitis following primary genital herpes in an immunocompetent female: An unusual case.

International journal of emergency medicine

Anti-NMDA receptor encephalitis with coexisting autoimmune GFAP astrocytopathy presenting with psychiatric symptoms leading to a suicide attempt: a case report.

The neuroradiology journal

Rasmussen encephalitis without atrophy and increased 11C-methionine PET uptake mimicking glioma: A case report.

Astrocyte Biology in CNS Inflammatory Diseases: A Clinical-Translational Perspective.

Brain atrophy in autoimmune encephalitis: epidemiology, pathophysiology, clinical manifestations, treatment, and prognosis-an update.

18F- FDG PET Reveals a Nucleus Accumbens-Centered Metabolic Network Correlating With Clinical Severity in Anti-LGI1 Encephalitis.

MedComm

Severe anti-NMDA receptor encephalitis in a pediatric patient presenting with status dystonicus as the primary clinical manifestation: A case report (CARE).

Medicine

The gut-brain axis: potential reshaping the future of anti-NMDAR encephalitis treatment.

Intermittent immunoadsorption in critically ill patients with neuroimmunological disorders: a retrospective study.

Frontiers in neurology

Personalized Ofatumumab therapy for autoimmune encephalitis: A case series of four patients.

Rapidly progressive dementia in a middle-aged woman: A case of probable sporadic Creutzfeldt-Jakob disease.

Medicine international

Parkinsonism & related disorders

A EIF2AK2 missense variant misdiagnosed as autoimmune encephalitis.

ANTIBODY-POSITIVE AUTOIMMUNE ENCEPHALITIS WITH ANTI-GAD65, ANTI-GABAARΑ1, AND ANTI-MGLUR5 ANTIBODIES: A CASE REPORT AND LITERATURE REVIEW.

Georgian medical news

Fatal Steroid-Refractory Autoimmune Encephalitis Following Sequential Immune Checkpoint Inhibitor Therapy in Squamous Non-Small Cell Lung Cancer.

OncoTargets and therapy

Research trends on herpes simplex encephalitis in children: a bibliometric analysis from 1975 to 2024.

Translational pediatrics

Clinical nuclear medicine

Comparative [18F]Florzolotau and [18F]FDG PET Imaging Patterns in Anti-IgLON5 Disease and Progressive Supranuclear Palsy.

European journal of neurology

Anti-IgLON5 Disease: A Systematic Review and Meta-Analysis.

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova

[Temporal lobe seizures of immune and structural etiology].

International evaluation of the SEIZUre Risk in Encephalitis (SEIZURE) score for predicting acute seizure risk.

BMJ open

Rapidly Progressive Dementia: Predictive Clues and a Proposed Diagnostic Approach Focused on Neurodegenerative Causes.

Epilepsy & behavior reports

Electroceuticals for Motherhood: Utility of responsive neurostimulation and Proactive antiseizure medication management in two pregnancies.

Endocrine, metabolic & immune disorders drug targets

A Case Report of Anti-GAD65 Antibody-Positive Autoimmune Encephalitis Associated with Diabetes.

Brain, behavior, and immunity

Biomarkers of neuroaxonal and astrocytic pathology in autoimmune encephalitis.

Neurological immune-related adverse events of immune checkpoint inhibitors: clinical and hematological risk factors.

Biological psychiatry global open science

Clinical Criteria to Guide Antineuronal Antibody Testing for People With Early and Persistent Psychosis Attending Mental Health Services.

The American journal of case reports

Neuropsychiatric Symptoms After HHV-6 Encephalitis in an Immunocompetent Child: A Case Report.

Bilateral thalamic encephalitis due to Epstein-Barr virus in an elderly patient: a case report and literature review.

Basal Ganglia Calcification With Treatment-Resistant Hypocalcaemia and Persistent Psychosis in an 18-Year-Old: A Case Report.

Experience of bortezomib use in refractory autoimmune neurological disorders.

Gut-derived Helicobacter rodentium aggravates Tfh/Tfr imbalance and neuroinflammation via PI3K/AKT activation in anti-NMDAR encephalitis mice.

Tissue & cell

Autoimmune glial fibrillary acidic protein astrocytopathy following human herpesvirus-7 infection: a case report.

Brain injury

The evolving etiologies of rapidly progressive dementia: a systematic review.

Translational psychiatry

Journal of neurology, neurosurgery, and psychiatry

Intrathecal Epstein-Barr virus reactivation in patients with autoimmune glial fibrillary acidic protein astrocytopathy.

Autoimmune encephalitis in first episode psychosis: Prospective non-interventional longitudinal study in tertiary psychiatric center.

Journal of clinical medicine

Differential Diagnosis of Infectious Versus Autoimmune Encephalitis Using Artificial Intelligence-Based Modeling.

Children (Basel, Switzerland)

Seronegative Immune-Mediated Cerebellar Ataxia in Children: Autoimmune Encephalitis Spectrum Disorder or a Distinct Entity?

Children (Basel, Switzerland)

Complications of Therapeutic Plasma Exchange in Pediatric Neuroimmune Disorders.

Differentiation between anti-CASPR2 encephalitis with initial psychiatric symptoms and primary psychiatric disorders, and a diagnostic prediction model: a prospective descriptive study.

The Journal of the Association of Physicians of India

An Unusual Case of Refractory Seizures.

Journal of neuroinflammation

Sez6L2 autoimmunity induces cerebellar ataxia in mice.

Prior murine neurotropic coronavirus infection ameliorates experimental autoimmune encephalitis.

Journal of autoimmunity

Overlapping autoimmune encephalitis with tripartite autoantibody positivity (NMDAR, GFAP, mGluR5) associated with papillary thyroid carcinoma: a case report.

Therapeutic Plasma Exchange in Pediatric Care: Insights from a Tertiary Care Centre Experience.

Indian pediatrics

Case Report: Co-occurring de novo SHANK3 and SRCAP variants in a patient with autoimmune encephalitis and exhibiting Phelan-McDermid syndrome features.

Frontiers in genetics

Case Report: KLHL11 encephalitis in a female patient with dual primary malignancies of breast and lung cancer: response to FcRn inhibitor therapy.