Expanding the Motor Band Sign in Motor Neuron Disease Using 7T MRI: Visualization of Cortical Layer-Dependent Iron Deposition in the Primary Motor Cortex.

Prospective Validation of the New PLS Diagnostic Criteria From PLS Natural History Study: EMG and Neurofilament Analyses.

The Amyotrophic Lateral Sclerosis House Call Program: A Single-Center Experience in the United States.

Trajectory of Mobility Function Decline for People With Motor Neuron Disease.

TBK1-Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia.

Involvement of Keap1/Nrf2 and the antioxidant defence in cytoprotective effects induced by cannabis polyphenols in SH-SY5Y neuronal cells.

Riluzole use and reasons for non-use in people with amyotrophic lateral sclerosis in Aotearoa New Zealand.

Establishing Diagnostic and Differential Diagnostic Criteria for Amyotrophic Lateral Sclerosis.

Demographic, clinical and genetic characteristics of patients with amyotrophic lateral sclerosis from two specialised centres in Austria.

Co-aggregation of annexin A11 and TDP-43 in FTLD/MND with primary lateral sclerosis phenotype.

Variably Protease-Sensitive Prionopathy: Two New Cases With Motor Neuron-Dementia Syndrome.

Motor band sign in 18F-FDG PET/CT studies: a biomarker of degenerative upper motor neuron disease? A study of three cases and literature review.

Case Series Assessing the Use of Levetiracetam for Gait Improvement in Primary Lateral Sclerosis.

Startle Reflex in Primary Lateral Sclerosis (PLS): A Comparison With Amyotrophic Lateral Sclerosis (ALS).

The Epidemiology of Primary Lateral Sclerosis: Results from a Population-Based Cohort.

The genetic architecture of primary lateral sclerosis in a cohort of Italian patients.

Expanding the spectrum of annexin A11 proteinopathy in frontotemporal lobar degeneration and motor neuron disease.

Spanish adaptation of the Primary Lateral Sclerosis Functional Rating Scale (PLSFRS).

Motor Cortex Coverage Predicts Signal Strength of a Stentrode Endovascular Brain-Computer Interface.

Development of a Human iPSC-Derived "Corticospinal Tract-on-a-Chip" for Neurodegenerative Disease Research.

Primary Lateral Sclerosis Natural History Study: Primary Lateral Sclerosis Functional Rating Scale and Other Outcomes Assessment.

Atypical features including acquired oculomotor apraxia in C9orf72-associated familial primary lateral sclerosis.

Serum NfL, but not GFAP, differentiates primary lateral sclerosis from adrenomyeloneuropathy and hereditary spastic paraplegia type 4.

Generation and characterization of two pluripotent stem cell lines from Primary Lateral Sclerosis (PLS) patients.

Amyotrophic Lateral Sclerosis Masquerading as Multiple System Atrophy with Parkinsonism and Anxiety as Initial Manifestations.

Whole genome sequencing analysis in primary lateral sclerosis (PLS) patients reveals mutations in neurological diseases-causing genes.

A Japanese familial spastic paraplegia associated with a missense UBQLN2 variant.

Unilateral Motor Band Sign in Hemiplegic Primary Lateral Sclerosis.

Neuroaxonal Degeneration as a Converging Mechanism in Motor Neuron Diseases (MNDs): Molecular Insights into RNA Dysregulation and Emerging Therapeutic Targets.

Toward therapeutic trials in primary lateral sclerosis.

Cortical Excitability as a Prognostic and Phenotypic Stratification Biomarker in Amyotrophic Lateral Sclerosis.

What Is in the Literature.

Burden of pathogenetic and likely pathogenetic variants in SPG7, SPG11 and AP4 genes in Amyotrophic Lateral Sclerosis. A case-control study.

Differentiating upper- and lower motor neuron diseases using automated acoustic analysis.

Inconsistent primary motor cortex glucose hypometabolism in primary lateral sclerosis.

Primary Lateral Sclerosis: Implications for Diagnostic Criteria From a Natural History Study in the Netherlands.

Primary Lateral Sclerosis (Progressive Spinobulbar Spasticity): Serial Analysis Over Many Years Increases Diagnostic Certainty.

Progression and life expectancy in primary lateral sclerosis.

Latest progress and challenges in drug development for degenerative motor neuron diseases.

New developments in imaging in ALS.

[Genetics of Motor Neuron Diseases and Hereditary Spastic Paraplegia].

Advances and research priorities in the respiratory management of ALS: Historical perspectives and new technologies.

Pathological laugher and crying in motor neuron diseases: a matter of bulbar and neurobehavioral involvement with sex imbalance.

Motor phenotypes of amyotrophic lateral sclerosis - a three-determinant anatomical classification based on the region of onset, propagation of motor symptoms, and the degree of upper and lower motor neuron dysfunction.

TDP-43 seeding activity in the olfactory mucosa of patients with amyotrophic lateral sclerosis.

Sensory Dysfunction in ALS and Other Motor Neuron Diseases: Clinical Relevance, Histopathology, Neurophysiology, and Insights from Neuroimaging.

Pseudobulbar affect: clinical associations, social impact and quality of life implications - Lessons from PLS.

HIV associated motor neuron disease (MND): A case series with systematic review of literature.

Cervical Collar Satisfaction and Functional Impact in Amyotrophic Lateral Sclerosis: A Survey Study.

The Role of Gastrostomy and Noninvasive Ventilation in Primary Lateral Sclerosis.

Hypothalamic atrophy in primary lateral sclerosis, assessed by convolutional neural network-based automatic segmentation.

Association between cardiometabolic diseases and the risk and progression of motor neuron diseases in Sweden: a population-based case-control study.

High-density multielectrode arrays bring cellular resolution to neuronal activity and network analyses of corticospinal motor neurons.

Diagnosing primary lateral sclerosis: a clinico-pathological study.

Motor Neuron Diseases and Central Nervous System Tractopathies: Clinical-Radiologic Correlation and Diagnostic Approach.

Development and validation a novel FEZF2 based fluorescent reporter for corticospinal motor neurons.

Utilizing quantitative susceptibility mapping to differentiate primary lateral sclerosis from progressive supranuclear palsy: A case report.

Amyotrophic lateral sclerosis established as a multistep process across phenotypes.

Phenotype and Genotype of Children with ALS2 gene-Related Disorder.

Safety and efficacy of memantine and trazodone versus placebo for motor neuron disease (MND SMART): stage two interim analysis from the first cycle of a phase 3, multiarm, multistage, randomised, adaptive platform trial.

A microRNA diagnostic biomarker for amyotrophic lateral sclerosis.

Longitudinal analysis of glymphatic function in amyotrophic lateral sclerosis and primary lateral sclerosis.

Comparative analysis of neurofilaments and biomarkers of muscular damage in amyotrophic lateral sclerosis.

An autopsy case of progressive supranuclear palsy with severe corticospinal tract degeneration.

Reliability and consistency of the Japanese version of the Primary Lateral Sclerosis Functional Rating Scale.

Primary lateral sclerosis associated with PSEN1 Pro284Leu variant in a Colombian family: Clinical and neuropathological features.

Upper motor neuron-predominant motor neuron disease presenting as atypical parkinsonism: A clinicopathological study.

Decoding genetic and pathophysiological mechanisms in amyotrophic lateral sclerosis and primary lateral sclerosis: A comparative study of differentially expressed genes and implicated pathways in motor neuron disorders.

Rare variant analyses validate known ALS genes in a multi-ethnic population and identifies ANTXR2 as a candidate in PLS.

Analysis and occurrence of biallelic pathogenic repeat expansions in RFC1 in a German cohort of patients with a main clinical phenotype of motor neuron disease.

Autonomic impairment in primary lateral sclerosis.

Serum neurofilament light chain in distinct phenotypes of amyotrophic lateral sclerosis: A longitudinal, multicenter study.

The periprocedural respiratory safety of propofol sedation in patients with a motor neuron disease undergoing percutaneous endoscopic gastrostomy insertion.

Could PLS represent a UMN-predominant ALS syndrome?

Acceptance and Commitment Therapy plus usual care for improving quality of life in people with motor neuron disease (COMMEND): a multicentre, parallel, randomised controlled trial in the UK.

Upper motor neuron signs in primary lateral sclerosis and hereditary spastic paraplegia.

Clinical and neuroimaging characteristics of primary lateral sclerosis with overlapping features of progressive supranuclear palsy.

Repeat expansions in AR, ATXN1, ATXN2 and HTT in Norwegian patients diagnosed with amyotrophic lateral sclerosis.

Harnessing Big Data in Amyotrophic Lateral Sclerosis: Machine Learning Applications for Clinical Practice and Pharmaceutical Trials.

Whole-body fasciculation detection in amyotrophic lateral sclerosis using motor unit MRI.

Supra- and infra-tentorial degeneration patterns in primary lateral sclerosis: a multimodal longitudinal neuroradiology study.

Primary lateral sclerosis: application and validation of the 2020 consensus diagnostic criteria in an expert opinion-based PLS cohort.

Phenotypic Spectrum of Progressive Supranuclear Palsy: Clinical Study and Apolipoprotein E Effect.

Primary Lateral Sclerosis: An Overview.

Primary lateral sclerosis: more than just an upper motor neuron disease.

Current challenges in primary lateral sclerosis diagnosis.

Upper Limb Movement Execution Classification using Electroencephalography for Brain Computer Interface.

A case of Mills' syndrome: initially characterized by one cerebral hemisphere atrophy and decreased brain metabolism then evolving into amyotrophic lateral sclerosis.

Ketamine-Assisted Psychodynamic Psychotherapy.

An autopsy case of diffuse atypical argyrophilic grain disease (AGD) with presenile onset and three-year course of motor and cognitive impairment.

Language deficits in primary lateral sclerosis: cortical atrophy, white matter degeneration and functional disconnection between cerebral regions.

Familial motor neuron disease: co-occurrence of PLS and ALS (-FTD).

Primary lateral sclerosis plus parkinsonism: a case report.

Primary lateral sclerosis.

The hereditary spastic paraplegias.

Creatine Kinase MB Isoenzyme Is a Complementary Biomarker in Amyotrophic Lateral Sclerosis.

Radiological correlates of pseudobulbar affect: Corticobulbar and cerebellar components in primary lateral sclerosis.

Serum Neurofilaments in Motor Neuron Disease and Their Utility in Differentiating ALS, PMA and PLS.

Role of the immune system in amyotrophic lateral sclerosis. Analysis of the natural killer cells and other circulating lymphocytes in a cohort of ALS patients.

Limited value of serum neurofilament light chain in diagnosing amyotrophic lateral sclerosis.

Advantages of routine next-generation sequencing over standard genetic testing in the amyotrophic lateral sclerosis clinic.

Cortico-muscular coherence in primary lateral sclerosis reveals abnormal cortical engagement during motor function beyond primary motor areas.

Genetic characterization of primary lateral sclerosis.

Regional spreading pattern is associated with clinical phenotype in amyotrophic lateral sclerosis.

Motor Band Sign in Primary Lateral Sclerosis: A Case Report Proposing the Need for an Imaging Biomarker.

Clinical and molecular spectrum of a large Egyptian cohort with ALS2-related disorders of infantile-onset of clinical continuum IAHSP/JPLS.

Primary Lateral Sclerosis: Can Rocuronium Be an Option?

Phenotypic correlates of serum neurofilament light chain levels in amyotrophic lateral sclerosis.

Utilizing machine learning and lipidomics to distinguish primary lateral sclerosis from amyotrophic lateral sclerosis.

Not a benign motor neuron disease: longitudinal imaging captures relentless motor connectome disintegration in primary lateral sclerosis.

Progress and challenges in directing the differentiation of human iPSCs into spinal motor neurons.

M1/precuneus ratio as a surrogate marker of upper motor neuron sign in ALS.

Assessment of Safety of a Fully Implanted Endovascular Brain-Computer Interface for Severe Paralysis in 4 Patients: The Stentrode With Thought-Controlled Digital Switch (SWITCH) Study.

Primary lateral sclerosis natural history study - planning, designing, and early enrollment.

Genotype-phenotype characterisation of long survivors with motor neuron disease in Scotland.

Globular glial tauopathy type II.

Current state of research on acupuncture for the treatment of amyotrophic lateral sclerosis: A scoping review.

A randomised controlled trial of acceptance and commitment therapy plus usual care compared to usual care alone for improving psychological health in people with motor neuron disease (COMMEND): study protocol.

Progressive motor neuron syndromes with single CNS lesions and CSF oligoclonal bands: never forget solitary sclerosis!

Case report: A variant of the FIG4 gene with rapidly progressive amyotrophic lateral sclerosis.

Mills' syndrome is a unique entity of upper motor neuron disease with N-shaped progression: Three case reports.

Clinical Spectrum of Tauopathies.

Parkinsonian Syndromes in Motor Neuron Disease: A Clinical Study.

Nonalcoholic Fatty Liver Disease in Patients with Inherited and Sporadic Motor Neuron Degeneration.

Segmental alterations of the corpus callosum in motor neuron disease: A DTI and texture analysis in 575 patients.

Iron-sensitive MR imaging of the primary motor cortex to differentiate hereditary spastic paraplegia from other motor neuron diseases.

Cerebellar pathology in motor neuron disease: neuroplasticity and neurodegeneration.

The Global Burden of Motor Neuron Disease: An Analysis of the 2019 Global Burden of Disease Study.

Arthroscopic Lateral Collateral Ligament Repair for the Acute Elbow Dislocation in Primary Lateral Sclerosis Patient: A Case Report.

Motor Band Sign in Motor Neuron Disease: A Marker for Upper Motor Neuron Involvement.

Acoustic Change Over Time in Spastic and/or Flaccid Dysarthria in Motor Neuron Diseases.

Parental and child adjustment to amyotrophic lateral sclerosis: transformations, struggles and needs.

Primary lateral sclerosis: diagnostic contribution of brain [18F]FDG PET/CT.

Frontotemporal Dementia as a Possible Manifestation of Primary Lateral Sclerosis: A Case Report and Literature Review.

Differential Diagnosis of Rare Subtypes of Progressive Supranuclear Palsy and PSP-Like Syndromes-Infrequent Manifestations of the Most Common Form of Atypical Parkinsonism.

Does limited EMG denervation in early primary lateral sclerosis predict amyotrophic lateral sclerosis?

Motor neuron disease in three asymptomatic pVal50Met TTR gene carriers.

[Oral hygiene in patients with motor neuron disease: a cross-sectional survey].

Primary Lateral Sclerosis Presenting With Focal Onset Spreading Through Contiguous Neuroanatomic Regions.

Home-monitoring of vital capacity in people with a motor neuron disease.

Asymmetrical Primary Lateral Sclerosis Presenting as Corticobasal Syndrome.

ALS2-Related Motor Neuron Diseases: From Symptoms to Molecules.

Cerebellar degeneration in primary lateral sclerosis: an under-recognized facet of PLS.

A Case Report on Robot-Aided Gait Training in Primary Lateral Sclerosis Rehabilitation: Rationale, Feasibility and Potential Effectiveness of a Novel Rehabilitation Approach.

AI-based protein structure databases have the potential to accelerate rare diseases research: AlphaFoldDB and the case of IAHSP/Alsin.

Imaging data reveal divergent longitudinal trajectories in PLS, ALS and poliomyelitis survivors: Group-level and single-subject traits.

Phenotypic categorisation of individual subjects with motor neuron disease based on radiological disease burden patterns: A machine-learning approach.

Upper motor neurons are a target for gene therapy and UCHL1 is necessary and sufficient to improve cellular integrity of diseased upper motor neurons.

CSF Heavy Neurofilament May Discriminate and Predict Motor Neuron Diseases with Upper Motor Neuron Involvement.

Half Wine Glass Appearance in Early Primary Lateral Sclerosis.

Amyotrophic lateral sclerosis (ALS) and the endocrine system: Are there any further ties to be explored?

The expanding clinical and genetic spectrum of alsin-related disorders: the first cohort of Brazilian patients.

Electromyographic findings in primary lateral sclerosis during disease progression.

Familial clustering of primary lateral sclerosis and amyotrophic lateral sclerosis: Supplementary evidence for a continuum.

Emotional Processing and Experience in Amyotrophic Lateral Sclerosis: A Systematic and Critical Review.

Propagation patterns in motor neuron diseases: Individual and phenotype-associated disease-burden trajectories across the UMN-LMN spectrum of MNDs.

Blenderized Tube Feeding and Enterostomy Tube Occlusions Among Adults with Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis.

Presenilin-1 Mutations Are a Cause of Primary Lateral Sclerosis-Like Syndrome.

Frontotemporal Pathology in Motor Neuron Disease Phenotypes: Insights From Neuroimaging.

Bradykinesia in motoneuron diseases.

The Upper Motor Neuron-Improved Knowledge from ALS and Related Clinical Disorders.

Role of the nigrosome 1 absence as a biomarker in amyotrophic lateral sclerosis.

Gold Coast diagnostic criteria: Implications for ALS diagnosis and clinical trial enrollment.

Utility of Transcranial Magnetic Simulation in Studying Upper Motor Neuron Dysfunction in Amyotrophic Lateral Sclerosis.

Combining structural and metabolic markers in a quantitative MRI study of motor neuron diseases.

The diagnostic challenge of primary lateral sclerosis: the integration of clinical, genetic and radiological cues.

Initial Cerebellar Ataxia in Hereditary Adult-Onset Primary Lateral Sclerosis.

Primary Lateral Sclerosis: Clinical, radiological and molecular features.

Lipidomics study of plasma from patients suggest that ALS and PLS are part of a continuum of motor neuron disorders.

SMN1 Duplications Are Associated With Progressive Muscular Atrophy, but Not With Multifocal Motor Neuropathy and Primary Lateral Sclerosis.

Upper Motor Neuron Disorders: Primary Lateral Sclerosis, Upper Motor Neuron Dominant Amyotrophic Lateral Sclerosis, and Hereditary Spastic Paraplegia.

Prevalence of multimorbidity and its impact on survival in people with motor neuron disease.

Distinguishing Primary Lateral Sclerosis from Parkinsonian Syndromes with the Help of Advanced Imaging.

Mutations and Protein Interaction Landscape Reveal Key Cellular Events Perturbed in Upper Motor Neurons with HSP and PLS.

Estimation of the prevalence and incidence of motor neuron diseases in two Spanish regions: Catalonia and Valencia.

Natural History of "Pure" Primary Lateral Sclerosis.

Improving mitochondria and ER stability helps eliminate upper motor neuron degeneration that occurs due to mSOD1 toxicity and TDP-43 pathology.

Clinical care and therapeutic trials in PLS.

Measuring disease progression in primary lateral sclerosis.

Neuroimaging in primary lateral sclerosis.

Better understanding the neurobiology of primary lateral sclerosis.

The clinical spectrum of primary lateral sclerosis.

Genetics of primary lateral sclerosis.

Neurophysiological features of primary lateral sclerosis.

Neuropathology of primary lateral sclerosis.

Diagnostics of Amyotrophic Lateral Sclerosis: Up to Date.

Progression of cognitive and behavioral disturbances in motor neuron diseases assessed using standard and computer-based batteries.

Case Report: Association of a Variant of Unknown Significance in the FIG4 Gene With Frontotemporal Dementia and Slowly Progressing Motoneuron Disease: A Case Report Depicting Common Challenges in Clinical and Genetic Diagnostics of Rare Neuropsychiatric and Neurologic Disorders.

Extra-motor cerebral changes and manifestations in primary lateral sclerosis.

The cutaneous silent period in motor neuron disease.

A case of vertebral artery compression syndrome mimicking primary lateral sclerosis.

Importance of lipids for upper motor neuron health and disease.

The Importance of Personally Reviewing Imaging for Clinical Correlation: A Case of Thoracic Spinal Stenosis Masquerading as a Motor Neuron Disease.