Raras
Buscar doenças, sintomas, genes...
Filariose
ORPHA:2034CID-10 · B74CID-11 · 1F66DOENÇA RARA

Uma doença parasitária causada por vermes que penetram nos tecidos e podem ser encontrados em qualquer parte do corpo humano. Esses vermes são transmitidos aos humanos pela picada de um mosquito ou mosca infectados, ou pelo consumo de água contaminada. Dependendo do subtipo, a doença pode causar inchaço crônico (linfedema), inflamação da pele, inchaços embaixo da pele e problemas nos olhos. Essa doença é um grande problema de saúde pública em muitos países tropicais e subtropicais. Seis tipos são conhecidos: filariose linfática, oncocercose, loaíase, mansonelose, dirofilariose e dracunculíase, causadas, respectivamente, por _Wuchereria bancrofti_ e vermes do gênero _Brugia_; _Onchocerca volvulus_; _Loa loa_; _Mansonella_; _Dirofilaria_; e _Dracunculus medinensis_. A eosinofilia tropical é considerada uma manifestação comum.

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Introdução

O que você precisa saber de cara

📋

Uma doença parasitária causada por vermes que penetram nos tecidos e podem ser encontrados em qualquer parte do corpo humano. Esses vermes são transmitidos aos humanos pela picada de um mosquito ou mosca infectados, ou pelo consumo de água contaminada. Dependendo do subtipo, a doença pode causar inchaço crônico (linfedema), inflamação da pele, inchaços embaixo da pele e problemas nos olhos. Essa doença é um grande problema de saúde pública em muitos países tropicais e subtropicais. Seis tipos são conhecidos: filariose linfática, oncocercose, loaíase, mansonelose, dirofilariose e dracunculíase, causadas, respectivamente, por _Wuchereria bancrofti_ e vermes do gênero _Brugia_; _Onchocerca volvulus_; _Loa loa_; _Mansonella_; _Dirofilaria_; e _Dracunculus medinensis_. A eosinofilia tropical é considerada uma manifestação comum.

Pesquisas ativas
4 ensaios
94 total registrados no ClinicalTrials.gov
Publicações científicas
8.487 artigos
Último publicado: 2026 Apr 15
Medicamentos
5 registrados
DOXYCYCLINE ANHYDROUS, DOXYCYCLINE, IMATINIB MESYLATE

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5 medicamentos registrados
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DOXYCYCLINE ANHYDROUSDOXYCYCLINEIMATINIB MESYLATEIMATINIBRESLIZUMAB

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
Unknown
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
0.0
Europe
Início
All ages
🏥
SUS: Sem cobertura SUSScore: 0%
CID-10: B74
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Entender a doença

Do básico ao detalhe, leia no seu ritmo

Preparando trilha educativa...

Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🧬
Pele e cabelo
7 sintomas
🩸
Sangue
6 sintomas
🫘
Rins
5 sintomas
🛡️
Imunológico
4 sintomas
🫃
Digestivo
3 sintomas
🦴
Ossos e articulações
3 sintomas

+ 18 sintomas em outras categorias

Características mais comuns

Vômitos
Cegueira
Erupção cutânea
Hiperceratose
Linfedema
Linfadenite
50sintomas
Sem dados (50)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 50 características clínicas mais associadas, ordenadas por frequência.

VômitosVomiting
CegueiraBlindness
Erupção cutâneaSkin rash
HiperceratoseHyperkeratosis
LinfedemaLymphedema

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico8.487PubMed
Últimos 10 anos200publicações
Pico2025148 papers
Linha do tempo
2026Hoje · 2026🧪 1991Primeiro ensaio clínico📈 2025Ano de pico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
3Fase 39
2Fase 23
1Fase 12
·Pré-clínico8
Medicamentos catalogadosEnsaios clínicos· 5 medicamentos · 17 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Filariose

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

🟢 Recrutando agora

2 pesquisas recrutando participantes. Converse com seu médico sobre a possibilidade de participar.

Outros ensaios clínicos

94 ensaios clínicos encontrados, 4 ativos.

Distribuição por fase
Ver todos no ClinicalTrials.gov
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Publicações mais relevantes

Timeline de publicações
2.547 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 2.547

#1

Emergence of a novel zoonotic brugian filarial infection during post-validation surveillance for lymphatic filariasis in Sri Lanka.

The Lancet regional health. Southeast Asia2026 Mar

Apesar da validação da eliminação da filaríase linfática no Sri Lanka, este estudo revelou o surgimento de uma nova espécie zoonótica de filária Brugia, transmitida por cães, que causa infecções em humanos, principalmente crianças. Para médicos e pacientes, é crucial reconhecer que esta infecção exige abordagens diagnósticas e terapêuticas específicas, pois sua identificação incorreta pode levar a respostas clínicas e programáticas inadequadas. A presença de cães como reservatório significa que as estratégias de controle focadas apenas em humanos são insuficientes, sublinhando a necessidade de uma vigilância integrada de "Saúde Única" para prevenir a reemergência da doença.

🇧🇷 traduzido
#2

Cross-sectional study to assess filarial infection among the never treated individuals in selected districts in India: a study protocol.

BMJ open2026 Mar 19

Este estudo na Índia visa identificar e avaliar a infecção por filaríase em indivíduos que **nunca receberam tratamento** durante campanhas de administração em massa de medicamentos (MDA). O objetivo é determinar se são **potenciais reservatórios da infecção** e compreender as **razões de sua não participação**. Para **pacientes e médicos**, é vital entender esses fatores, pois isso permitirá desenhar estratégias mais eficazes, garantindo que todos sejam alcançados pelo tratamento e, assim, **acelerar a eliminação global da filaríase** até 2030.

🇧🇷 traduzido
#3

Altitudinal and household breeding patterns of the medically important mosquitoes Aedes aegypti, Aedes albopictus and Culex quinquefasciatus in Nepal.

PloS one2026

Este estudo no Nepal revelou a ampla presença de mosquitos vetores de doenças, incluindo o *Culex quinquefasciatus* (principal vetor da filariose linfática) e espécies de *Aedes* (vetores de dengue), mesmo em altitudes elevadas. Esses mosquitos, encontrados em recipientes comuns como garrafas plásticas e tambores, coexistem frequentemente nas mesmas residências, aumentando o risco de múltiplas infecções. Isso ressalta a necessidade urgente de vigilância integrada e estratégias de controle para proteger a população contra filariose e arboviroses.

🇧🇷 traduzido
#4

Noise and neglect: Social-media signals expose attention gaps for dengue, chikungunya, lymphatic filariasis and kala-azar in India's vector-borne NTDs.

PLoS neglected tropical diseases2026 Mar

Um estudo sobre a atenção online a doenças negligenciadas na Índia revelou que a Filariase Linfática, em particular, recebe uma visibilidade desproporcionalmente alta nas mídias sociais em comparação com seu número real de casos. Para pacientes e médicos, isso indica um engajamento público significativo com o tema, sugerindo a importância de campanhas de saúde pública estratégicas e direcionadas que capitalizem essa atenção para educar sobre prevenção e tratamento, alinhando a comunicação digital com as necessidades da comunidade.

🇧🇷 traduzido
#5

The impact of the termination of Lymphatic Filariasis mass drug administration on Soil-transmitted Helminth prevalence in school children in Malawi.

PLoS neglected tropical diseases2026 Feb

A interrupção dos programas de tratamento em massa para Filariose Linfática em Malawi levou a um ressurgimento preocupante de infecções por vermes intestinais comuns (*Ascaris lumbricoides*) em crianças em idade escolar. Este aumento foi observado mesmo com a continuidade da quimioterapia preventiva específica para vermes, indicando que o tratamento comunitário abrangente da Filariose era crucial para manter essas infecções sob controle. Para médicos e pacientes, isso sublinha o risco de um aumento de verminoses após o término de programas de saúde pública amplos, exigindo investigação urgente sobre as causas do ressurgimento, incluindo possível resistência a medicamentos.

🇧🇷 traduzido

Publicações recentes

Ver todas no PubMed

📚 EuropePMC4.736 artigos no totalmostrando 197

2026

Emergence of a novel zoonotic brugian filarial infection during post-validation surveillance for lymphatic filariasis in Sri Lanka.

The Lancet regional health. Southeast Asia
2026

Acquired smooth muscle hamartoma mimicking scrotal filariasis: A rare case report.

Urology case reports
2026

Lived experiences, stigma and impacts of lymphatic filariasis: a scoping review.

International health
2026

Cross-sectional study to assess filarial infection among the never treated individuals in selected districts in India: a study protocol.

BMJ open
2026

Altitudinal and household breeding patterns of the medically important mosquitoes Aedes aegypti, Aedes albopictus and Culex quinquefasciatus in Nepal.

PloS one
2026

Noise and neglect: Social-media signals expose attention gaps for dengue, chikungunya, lymphatic filariasis and kala-azar in India's vector-borne NTDs.

PLoS neglected tropical diseases
2026

Circumferential Negative Pressure Lymphedema Therapy: A Novel Rapid Perioperative Decongestion Strategy for Advanced Stage III-IV Lymphedema.

Cureus
2026

High prevalence of bancroftian filariasis and comorbidities in the eastern coalfield regions of West Bengal, India following COVID-19 disruption.

Scientific reports
2026

Biochemical, molecular, and in silico insights into the effects of cyphenothrin on Culex quinquefasciatus mosquitoes.

Parasites &amp; vectors
2026

Cost-Effectiveness of Triple Versus Dual-Drug Therapy for Elimination of Lymphatic Filariasis in India.

Value in health regional issues
2026

Post elimination of lymphatic filariasis: a situation analysis of brugian filariasis and vector potentialities within the filarial transmission belt in Sri Lanka.

Parasites &amp; vectors
2025

[Mosquito-borne diseases in the Republic of Djibouti: a review of the literature].

Medecine tropicale et sante internationale
2026

From neglect to empowerment: impact of vocational rehabilitation on quality of life among disabled filarial lymphoedema patients in a brugian-endemic region of South India-a mixed methods evaluation.

Transactions of the Royal Society of Tropical Medicine and Hygiene
2026

Sociodemographic determinants of lymphatic filariasis knowledge among refugees in Cameroon.

Discover public health
2025

Design of an implementation research study for a digital omnichannel community engagement and risk communication intervention for the prevention and control of vector-borne diseases in India: the OMNIVEC-India study protocol.

Frontiers in public health
2026

High-Dose Rifampicin Plus Albendazole Rapidly Clears Lymphatic Filariasis Circulating Filarial Antigen in a Randomised Clinical Trial: A Promising Step Toward Short-Course Macrofilaricidal Therapy.

Pathogens (Basel, Switzerland)
2026

Enablers of Post-Validation Surveillance for Lymphatic Filariasis in the Pacific Islands: A Nominal Group Technique and Expert Elicitation.

Tropical medicine and infectious disease
2026

Integrated Approaches to Surveillance of Lymphatic Filariasis and Other Infectious Diseases in the Pacific Islands.

Tropical medicine and infectious disease
2026

The impact of the termination of Lymphatic Filariasis mass drug administration on Soil-transmitted Helminth prevalence in school children in Malawi.

PLoS neglected tropical diseases
2026

Measuring Progress of 2030 Skin-Related Neglected Tropical Diseases Sustainable Development Goals.

JAMA dermatology
2026

Deep phenotypic profiling uncovers cryptic effects of antifilarial drugs.

bioRxiv : the preprint server for biology
2026

Pharmacokinetics, safety, and tolerability of an oxfendazole tablet formulation: a phase 1, randomized, placebo-controlled trial in healthy African volunteers.

Antimicrobial agents and chemotherapy
2026

Phytol from Sphaeranthus indicus: A Natural Insecticide Against Aedes aegypti and Culex quinquefasciatus.

Acta parasitologica
2026

Vulval Lymphedema: An Under-Recognized Clinical Manifestation of Lymphatic Filariasis.

The American journal of tropical medicine and hygiene
2026

Establishing a filarial clinical research platform in a resource-limited setting: Lessons and experiences from Tanzania.

PLoS neglected tropical diseases
2026

Filariasis: An Unfamiliar Infection.

Journal of breast imaging
2026

Defining onchocerciasis transmission zones: Integrating operational insights with genomic and ecological advances.

International health
2025

Review of selected mosquito-borne diseases: arboviruses (dengue, chikungunya, Zika, West Nile, Japanese encephalitis, yellow fever) and parasitic diseases (malaria, lymphatic Filariasis).

Frontiers in public health
2026

Deep venous thrombosis due to Wuchereria bancrofti-induced reactive hypereosinophilia syndrome: a case report.

Transactions of the Royal Society of Tropical Medicine and Hygiene
2026

Catching a zebra in a surgical ward: atypical case of chylothorax caused by filariasis in a lupus patient-a case report from a surgical perspective.

Journal of cardiothoracic surgery
2025

Insights and contrasts between Western and Eastern practices of surgical management of lower limb lymphedema: A systematic review and narrative synthesis.

JPRAS open
2026

The Death to Onchocerciasis and Lymphatic Filariasis (DOLF) project: Accomplishments and ongoing research.

PLoS neglected tropical diseases
2026

Cross-sectional epidemiological assessment of lymphatic filariasis situation in areas under post-mass drug administration surveillance and the associated risk of transmission in the context of migrants in India: a study protocol.

BMJ open
2026

Global Lymphatic Filariasis Post-Validation Surveillance Activities in 2025: A Scoping Review.

Tropical medicine and infectious disease
2026

Barriers and Facilitators to Implementing Post-Validation Surveillance of Lymphatic Filariasis in Pacific Island Countries and Territories: A Conceptual Framework Developed from Qualitative Data.

Tropical medicine and infectious disease
2026

Imported Eosinophilia in Migrants from Endemic Areas in Spain.

Tropical medicine and infectious disease
2025

Finding the Gaps: Integrated Serosurveillance and Spatial Clustering of Vaccine Preventable Diseases in Samoa, 2018-2019.

Tropical medicine and infectious disease
2025

Spatial Risk Factors of Vector-Borne Diseases in Pacific Island Countries and Territories: A Scoping Review.

Tropical medicine and infectious disease
2025

Vitamin A and D levels in patients with filarial lymphedema and healthy volunteers in Puducherry, India.

Frontiers in nutrition
2026

Beyond the breast: Mammographic manifestations of systemic disease.

Current problems in diagnostic radiology
2026

Transmission status of lymphatic filariasis in hotspots of filarial infection, persistent districts of nepal during post-MDA surveillance.

PloS one
2026

Incidental Detection of Microfilariae in Saguinus bicolor and Saguinus midas From Central Amazon.

Journal of medical primatology
2026

Patient perspectives and barriers to effective home-based care in lymphatic filariasis: A mixed methods study from Puducherry, India.

PLoS neglected tropical diseases
2026

Ocular filariasis manifesting as an orbital cellulitis and conjunctival nodule: a case report.

Orbit (Amsterdam, Netherlands)
2026

Exploring the landscape of lymphatic filariasis research in India: A scientometric analysis of two decades from 2000 to 2024.

PLoS neglected tropical diseases
2026

Microfilaria at a post-mastectomy surgical site: An incidental cytological finding.

Tropical doctor
2026

Do we have a match? Calculating the potential for integrating neglected tropical disease control programmes for sustainable public health policy.

Acta tropica
2025

Neglected by Design: Occupational Parasitic Infections in India's Lower Castes.

The Yale journal of biology and medicine
2025

Living with Filariasis: Unseen Struggles of a Neglected Disease.

The Yale journal of biology and medicine
2025

Meta-analysis of the prevalence of lymphatic filariasis infection in mosquito vectors.

Frontiers in cellular and infection microbiology
2025

Neglected tropical diseases elimination in Africa: lessons from regional control programmes.

Tropical medicine and health
2025

Assessment of mosquito species communities biting humans and their livestock in the forest hills of Karen state, Myanmar: a cross-sectional survey in six villages.

Parasites &amp; vectors
2025

Community knowledge, attitudes, and practices regarding mosquito-borne diseases in rural Uttar Pradesh, India.

Journal of vector borne diseases
2025

Lymphatic Filariasis in India: A Historical and Contemporary Overview.

Journal of vector borne diseases
2026

Microfilaruria of morphologically identified Dirofilaria repens and Brugia spp. in one cat and two dogs: Case series.

Topics in companion animal medicine
2025

An Unusual Presentation of Human Parotid Filariasis.

Tropical medicine and infectious disease
2026

Family quality of life and associated factors among people with leprosy or podoconiosis/lymphatic filariasis with visible disabilities and their family members in Ethiopia: a baseline study for a randomized controlled trial.

Transactions of the Royal Society of Tropical Medicine and Hygiene
2025

Reversal of filarial serpin Wb123-urokinase plasminogen activator receptor mediated alternative macrophage activation by monoclonal antibody.

PLoS neglected tropical diseases
2026

Larvicidal and macrofilaricidal efficacy of closantel and morantel against mosquito larvae and Setaria digitata nematodes.

Experimental parasitology
2025

Revisiting the epidemiology of schistosomiasis and soil-transmitted helminthiasis in Chad: insights for improved interventions.

International health
2025

The role of molecular xenomonitoring for assessing the impact of Ivermectin, Diethylcarbamazine Citrate and Albendazole triple-drug treatment against lymphatic filariasis: A cross-sectional study in the Kenyan coastal region.

PLOS global public health
2025

Diethylcarbamazine elicits calcium signals by activation of Brugia malayi TRP-2b channels heterologously expressed in HEK293 cells.

Scientific reports
2025

Wbm0152, an outer membrane lipoprotein of the Wolbachia endosymbiont of Brugia malayi, inhibits yeast ESCRT complex activity.

PLoS pathogens
2025

Two decades of filariasis in India: Insights into prevalence, diagnostic challenges, and strategies for elimination by 2027.

IJID regions
2025

Coverage evaluation of mass drug administration for lymphatic filariasis in four endemic districts of Jharkhand, India.

Journal of health, population, and nutrition
2025

Bayesian hierarchical spatial ecological model assessing the nexus of vegetation index, insecticide-treated bed-nets and livestock cattle density on lymphatic filariasis transmission.

BMC public health
2025

Risk factors of lymphatic filariasis in Asia: a systematic review.

BMC infectious diseases
2025

Semi-annual and annual mass drug administration of diethylcarbamazine and albendazole are equally effective regimens for eliminating lymphatic filariasis in Papua New Guinea.

PLoS neglected tropical diseases
2026

Elephantiasis and verrucous lesions in an Ethiopian man living in Italy.

Journal of infection and public health
2025

Community engagement in mass drug administration participatory interventions: A scoping review.

PLoS neglected tropical diseases
2025

Zoonotic filariasis and its public health significance: a comprehensive literature review.

Frontiers in microbiology
2025

Molecular Characterisation of Fungi Populations in the Chronic Wounds of Filarial Lymphedema Patients in Southern Ghana: A Cross-Sectional Study.

Health science reports
2025

Determining Etiology of Elephantiasis and Associated Factors in Hawella Tula, Sidama Region, Ethiopia.

Research and reports in tropical medicine
2025

A framework for guiding integrated disease control measures through multipathogen surveillance.

medRxiv : the preprint server for health sciences
2025

Field trial finds promising evidence on Spinosad: a bio-larvicide for mosquito control in urban settings in Bengaluru, India.

Malaria journal
2025

Achieving elimination of soil-transmitted helminthiasis as a public health problem in Mali.

BMJ global health
2025

Structure-based virtual screening of β-tubulin and thioredoxin reductase in Brugia malayi: a step toward novel anti-filarial agents.

In silico pharmacology
2025

Lymphatic filariasis remained silent until presentation with huge abdominal mass mimicking malignancy: a case report.

ASM case reports
2025

Blood parasitic diseases in India: Current landscape, challenges, and the road ahead.

Tropical parasitology
2025

Prevalence and risk factors for Acanthocheilonema reconditum infection in dogs in the municipality of Lages, Santa Catarina, Brazil.

Veterinary parasitology, regional studies and reports
2025

Bacillus altitudinis: a sustainable mosquito controlling biopesticide isolated from the rhizospheric soil of Nypa fruticans in mangrove forest.

BMC microbiology
2025

Implementation of basic package of care improved socio-economic conditions of lymphedema patients in rural Mali after two years follow-up.

PLOS global public health
2025

Double Trouble in the Thyroid: Coexistence of Hurthle Cell Neoplasm and Microfilarial Infestation.

Discoveries (Craiova, Romania)
2025

Anopheles barbirostris in Indonesia: A more complex metapopulation than expected.

PloS one
2025

Brugia malayi miRNAs and potential targets within the feline host (Felis catus).

Current research in parasitology &amp; vector-borne diseases
2025

In silico screening of flavonoid-based inhibitors targeting UDP-galactopyranose mutase of Brugia malayi for lymphatic filariasis drug design.

Computers in biology and medicine
2025

Clinical Manifestations of Lymphatic Filariasis and Practice of Vector Control Measures after 15 Years of Mass Drug Administration: A Rapid Epidemiological Study from Odisha.

Indian journal of community medicine : official publication of Indian Association of Preventive &amp; Social Medicine
2025

COMET-LF: a compartmental model of dynamics of infection, disease, and elimination strategies for lymphatic filariasis.

BMC infectious diseases
2025

Patient journeys for neglected tropical diseases in rural sub-Saharan Africa: a scoping review.

Infectious diseases of poverty
2025

Prevalence of Malaria Among Individuals Living With Lymphedema in Kamwenge District, Western Uganda.

Cureus
2025

Investigating the resurgence of malaria in Rwanda: factors contributing to rising cases amidst near-eradication success and strategies for sustained control.

Annals of medicine and surgery (2012)
2026

Elimination is not the end: experience in handling the last residual filariasis focus in China.

Transactions of the Royal Society of Tropical Medicine and Hygiene
2025

Identification of key pharmacophore feature motifs from the potent leads of the major antioxidant enzymes of W. bancrofti and in vitro validation studies of the key enzyme WbPrx6 using the model organism S. digitata.

Computers in biology and medicine
2025

Acute Brugian filariasis in a German tourist after short-term travel to Sri Lanka, 2025.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
2025

Molecular xenomonitoring highlights post-MDA surveillance priorities for sustained Wuchereria bancrofti elimination in Burkina Faso.

Tropical medicine and health
2025

Comparison of Platelet Functions, Plasma Proteins and Lipids in Filarial and Non-Filarial Edema Patients.

Parasite immunology
2025

Molecular detection of filarioid nematodes (Nematoda: Onchocercidae) in wild mammals from different Brazilian biomes.

Parasitology
2025

Zoonotic brugian filariasis past and present trends in malaysia: A systematic review and proportionate meta-analysis.

Scientific reports
2025

Moxidectin combination therapies for lymphatic filariasis-36-month follow-up.

The Lancet. Infectious diseases
2025

A Triple Regimen as an Alternative Treatment for Lymphatic Filariasis in a Non-endemic Area in Indonesia: A Case Report.

Cureus
2025

Structural Barriers and the Future of AI in Global Health: Lessons From Eradicable Diseases.

Cureus
2025

Rare case of extralymphatic dirofilariasis presenting as a facial subcutaneous nodule in non-endemic region of Spain.

IDCases
2025

Piloting lymphoedema management for lymphatic filariasis: experiences and perceptions of patients and stakeholders from Kwale county, coastal Kenya.

BMC public health
2025

Epidemiology of Dirofilaria immitis and Acanthocheilonema reconditum in dogs from non-endemic municipalities at different altitudes in the State of Rio de Janeiro, Brazil.

Research in veterinary science
2025

Heat, Humidity, and Hematuria: Glomerular Complications of Tropical Infections.

Glomerular diseases
2025

Immunoendocrine network under conditions of diabetes-filariasis co-morbidity DMLF6.

Scientific reports
2025

Brugia malayi and other filarial parasite species in animals in areas endemic for lymphatic filariasis in Belitung District, Indonesia.

PLoS neglected tropical diseases
2026

Autochthonous human subconjunctival dirofilariasis in europe: a case report from Italy and literature review.

European journal of clinical microbiology &amp; infectious diseases : official publication of the European Society of Clinical Microbiology
2025

Dispersal and survival of gamma-irradiated Culex quinquefasciatus: Implications for sterile insect technique applications.

Open veterinary journal
2025

Commentary on the molecular and morphological identification of microfilariae in domestic chickens: Future perspectives.

Open veterinary journal
2026

Comprehensive genomic analysis and functional characterization of a new entomopathogenic strain, Bacillus thuringiensis subsp. israelensis VCRC B646, antagonistic to mosquito vectors (Diptera: Culicidae), isolated from soil in Tamil Nadu, India.

Pest management science
2025

Global Epidemiology of Vector-Borne Parasitic Diseases: Burden, Trends, Disparities, and Forecasts (1990-2036).

Pathogens (Basel, Switzerland)
2025

No evidence of Wuchereria bancrofti infection in Anopheles species after 10 years without mass drug administration: a molecular xenomonitoring study in Hauts-Bassins, Burkina Faso.

Tropical medicine and health
2025

From Burden to Breakthrough: The Impact of Mass Drug Campaigns on Microfilaria Trends Based on Evidence From Sentinel Site Surveillance in Rural Nagpur, Maharashtra, India, Over Two Decades.

Cureus
2025

Lymphedema is a rare manifestation of lymphoma: A case series and literature review.

Oncology letters
2026

Active constituent nonacosane from Sphaeranthus indicus (Asterales: Asteraceae) leaves as a potent larvicidal agent against Aedes aegypti (Diptera: Culicidae) and Culex quinquefasciatus (Diptera: Culicidae).

Parasitology international
2025

Detection of potential transmission foci of lymphatic filariasis using molecular xenomonitoring in Huahine, French Polynesia.

PLoS neglected tropical diseases
2025

Assessing the need to implement mass drug administration against Wuchereria bancrofti infection using both human serology and xenomonitoring in the urban conurbation of Monrovia, Liberia.

PLoS neglected tropical diseases
2025

Disability and quality of life assessment using WHODAS-12 items 2.0 and EQ-5D-5L in a rural area endemic for loiasis in the Republic of Congo: A population-based cross-sectional study (the MorLo project).

PLoS neglected tropical diseases
2025

A multicenter evaluation of the Filariasis IgG4 Rapid Test for detection of lymphatic filariasis.

Acta tropica
2026

Breast lump: A rare presentation of filariasis.

Tropical doctor
2026

"String sign"- acute lymphangitis in the forearm following triple drug therapy for bancroftian filarial infection.

Journal of vector borne diseases
2025

Positive allosteric modulation of emodepside sensitive Brugia malayi SLO-1F and Onchocerca volvulus SLO-1A potassium channels by GoSlo-SR-5-69.

PLoS pathogens
2025

Harnessing the potential of phytochemicals to design anti-filarial molecules targeting the MurE enzyme of Brugia malayi: a hierarchical virtual screening and molecular dynamics simulation study.

SAR and QSAR in environmental research
2025

Impact of diabetes mellitus on adenolymphangitis episodes in patients with filarial lymphedema-Towards an integrated care approach.

PLoS neglected tropical diseases
2025

Unlocking the blueprint to eliminating neglected tropical diseases: A review of efforts in 50 countries that have eliminated at least 1 NTD.

PLoS neglected tropical diseases
2025

Natural infection of filarioid nematodes in mosquitoes: An approach to neglected disease xenosurveillance and prevention in intercontinental human transit areas in Darién.

PLoS neglected tropical diseases
2025

Phytotherapeutic efficacy of Mitragyna parvifolia for acute dermatolymphangioadenitis (ADLA).

Journal of parasitic diseases : official organ of the Indian Society for Parasitology
2025

Discovery of potentially novel species of the Onchocercidae (Nematoda: Filarioidea) in Burmese fighting chickens (Gallus gallus): Genetic insights into avian filariasis and co-infection with Plasmodium juxtanucleare.

Current research in parasitology &amp; vector-borne diseases
2025

Screening for infectious and neglected tropical diseases among newly arrived migrants from Africa and Asia: a retrospective study from Verona province, Italy.

Tropical medicine and health
2025

Loiasis presenting as monolateral cervical lymphadenopathy.

Journal of travel medicine
2025

Larvicidal mechanism of the rare sesquiterpene ishwarol B from Piper alatipetiolatum (Piperaceae) against Aedes aegypti, Anopheles darlingi, and Culex quinquefasciatus (Culicidae): oxidative damage, defense enzyme modulation, and acetylcholinesterase inhibition.

Chemico-biological interactions
2025

The Impact of Displacement on Skin-Related Neglected Tropical Diseases in Sudan.

Clinical and experimental dermatology
2025

Chronic kidney disease related to Loa loa microfilaremia in a rural area of the Republic of Congo: a population-based cross-sectional study.

Infectious diseases of poverty
2025

Parasitic infections and the development of endomyocardial fibrosis: systematic review of case reports and case series.

Tropical medicine and health
2025

Validation of the Brugia Test Plus to detect IgG4 antibodies in individuals from Belitung Timur, a Brugia malayi endemic area in Indonesia.

PLoS neglected tropical diseases
2025

The Burden of Neglected Tropical Diseases in Rwanda: A Scoping Review.

Health science reports
2025

Clinical profile and Mass Drug Administration coverage in patients with lymphatic filariasis: A descriptive study.

Journal of family medicine and primary care
2025

A virtual screening strategy to repurpose antifolate compounds as W.bancrofti DHFR inhibitors.

Bioorganic &amp; medicinal chemistry letters
2025

Social and healthcare-seeking experiences of people affected with lymphedema in Bangladesh.

PLoS neglected tropical diseases
2025

Lymphoedema - Filariasis or soft tissue sarcoma? A case report.

Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia
2025

Confirmatory mapping for lymphatic filariasis a decade after baseline endemicity assessment in highly urbanized settings of Lagos, Nigeria.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2025

Effects of doxycycline on prepatent and patent infections of Brugia pahangi in dogs and observations on the growth and survival of L3 in jirds and dogs.

Veterinary parasitology
2025

Larvicidal potential of Pseudomonas mosselii isolated from Aedes (Diptera: Culicidae) egg surfaces against dengue vector mosquitoes and its impact on non-target organisms.

Medical and veterinary entomology
2025

Larvicidal and Pupicidal Activity of Neonicotinoid Insecticide Imidacloprid against Southern House Mosquito, Culex Quinquefasciatus (Say) (Diptera: Culicidae).

Acta parasitologica
2025

Detection of Filarial IgG and IgM Antibodies Among Individuals With Lymphedema in the Kamwenge District, Western Uganda.

Cureus
2026

Retrospective Review With Genetic Analysis of Canine Microfilarial Dermatitis in the Western United States.

Veterinary dermatology
2025

A Novel Filarial-Multiplexed Probe-Quantitative PCR for the Advance in the Diagnosis of Multiple Infections With Human Filariasis.

Tropical medicine &amp; international health : TM &amp; IH
2025

Public health surveillance of tropical diseases in Madagascar: a scoping review of population burden, intervention strategies, and health system responses.

BMC public health
2025

Current Gaps in Survey Design and Analysis for Molecular Xenomonitoring of Vector-Borne Neglected Tropical Diseases: A Systematic Review.

Tropical medicine &amp; international health : TM &amp; IH
2025

Access and Awareness of Morbidity Management and Disability Prevention for Lower Limb Lymphatic Filariasis in Post-Mass Drug Administration Districts in Southern India.

The American journal of tropical medicine and hygiene
2025

Preliminary evaluation of inactivated antigens as diagnostic controls in molecular detection of vector-borne diseases in low-resource settings.

Journal of vector borne diseases
2025

PD-L2 Inhibits Protective Immunity, Th2 Cell Functional Quality, and GATA-3 Expression During Filarial Nematode Infection.

European journal of immunology
2025

Feasibility of interrupting the transmission of soil-transmitted helminths: the DeWorm3 community cluster-randomised controlled trial in Benin, India, and Malawi.

Lancet (London, England)
2025

Epidemiological monitoring survey to assess the impact of mass drug administration with triple-drug regimen in lymphatic filariasis elimination programme in an endemic district in Southern India.

PLoS neglected tropical diseases
2025

The changing neglected tropical disease landscape in Africa: implications for policy, practice, and strengthening health systems.

Health affairs scholar
2025

Influence of the physicochemical characteristics of mosquito breeding sites in domestic environments on the distributions of Anopheles, Aedes and Culex mosquitoes in Benin.

Tropical medicine and health
2025

Detection of Dirofilaria repens and Mansonella llewellyni in the United States by Wolbachia Surveillance.

Transboundary and emerging diseases
2025

Subcutaneous Postauricular Filariasis in an Adult Male: An Extremely Rare Presentation.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
2025

Field evaluation of Standard Q Filariasis Antigen Test for Lymphatic Filariasis (LF) during a pre-transmission assessment survey in Sierra Leone, 2022.

PLoS neglected tropical diseases
2025

Eco-Friendly Synthesis of Silver Nanoparticles and Its Larvicidal Property Against Malaria, Filariasis, and Dengue Vectors.

Luminescence : the journal of biological and chemical luminescence
2025

Sequence Localization of SeGPx in S. digitata Genome Contigs and Determination of its Presence in the Whole Worm Extract.

Acta parasitologica
2025

Recurrent Chyluria Revisited: Lymphangiographic Diagnosis of Pyelolymphatic Fistula With Insights on Endolymphatic Interventions.

Cureus
2025

Averting collapse: Reimagining the NTDs ecosystem through G20 health diplomacy and science innovation.

Microbes and infection
2025

Acceptability of mass drug administration for lymphatic filariasis in Baglung Municipality of Nepal: A mixed-method study.

PLOS global public health
2025

Exploring the Antibacterial, Antioxidant and Larvicidal Effects against Culex quinquefasciatus of Nigella sativa Seeds and its Silver Nanoparticles.

Acta parasitologica
2025

Integrating geospatial tools is crucial for enhancing control strategies against human lymphatic filarial infections in Ghana: A comprehensive review.

Parasite epidemiology and control
2025

Testicular Lymphatic Filariasis.

Radiographics : a review publication of the Radiological Society of North America, Inc
2025

Host environment shapes filarial parasite fitness and Wolbachia endosymbionts dynamics.

PLoS pathogens
2025

Reactive case detection can improve the efficiency of lymphatic filariasis surveillance compared to random sampling, Samoa 2023.

PLoS neglected tropical diseases
2025

Global insights can accelerate India's journey towards the elimination of lymphatic filariasis as a public health problem.

BMJ global health
2025

Colossal Penile Filariasis with Scrotal Lymphangiectasia: The Forgotten Nightmare.

Clinical and experimental dermatology
2025

Evaluating the effectiveness of mass drug administration on lymphatic filariasis transmission and assessment of post-mass drug administration surveillance in Nigeria's Federal Capital Territory.

Infectious diseases of poverty
2025

Proteomic analysis unveils host-parasite interactions in Aedes togoi infected with Dirofilaria immitis and Brugia pahangi.

PloS one
2025

Healthcare Undergraduates' Perception and Practice Regarding Lymphatic Filariasis and Mass Drug Administration in a Tertiary Care Facility in Eastern India.

Cureus
2025

A mixed-method study to improve outcome of mass drug administration in two TAS failed districts of Uttar Pradesh, India.

PLoS neglected tropical diseases
2025

Surgical management of the giant scrotal lymphedema: A case report at a tertiary facility in northern Tanzania.

International journal of surgery case reports
2025

Prevalence and patterns of multiple long-term conditions among lymphatic filariasis patients in Odisha, India: a community-based cross-sectional study.

BMC public health
2026

Coverage and determinants of Mass Drug Administration against lymphatic filariasis in Southeast Asian regional countries during the end-game strategy: A systematic review and meta-analysis.

Journal of vector borne diseases
2025

Survey of filarial infection in Japanese black bears (Ursus thibetanus japonicus) around Lake Towada area.

The Journal of veterinary medical science
2025

Comparative analysis of skin microbiome of patients with filarial lymphedema and healthy individuals.

PloS one
2025

Simulium larvae susceptibility to temephos and the effect of 10 weeks of treatment of the Mbende tributary in the Nkam-Wouri River drainage of Cameroon on larval density and adult fly biting rates.

Parasites &amp; vectors
2025

Assessment of the effectiveness of public art in improving knowledge, attitude, practices and mitigation of stigmatization regarding neglected tropical diseases in South Eastern, Nigeria.

PLoS neglected tropical diseases
2025

A Next-Generation Human Lymphatic Filariasis Vaccine Candidate, rBmHAXT, for Clinical Development.

Research square
2025

Structure-based designing of anti-filarial molecules targeting the key antioxidant enzyme glutathione peroxidase (GPx) of Wuchereria bancrofti: An integrated in silico and in vitro approach.

Computers in biology and medicine
2025

Remote Sensing and GIS-Based Study to Predict Risk Zones for Mosquito-Borne Diseases in Cuttack District, Odisha, India.

GeoHealth
2025

Examining the overlap in lymphatic filariasis prevalence and malaria insecticide-treated net access-use in endemic Africa.

PLoS neglected tropical diseases
2025

Evaluation of sampling strategies for assessing lymphatic filariasis endemic status of a non-MDA district in South India.

PLoS neglected tropical diseases
2025

New Insights into the Biology, Ecology, and Management of Mosquitoes.

Insects
2025

Morphological and molecular characterization of microfilariae in chickens (Gallus gallus domesticus) in Northeastern Thailand.

Open veterinary journal
2025

Overexpression of cytochrome P450 and esterase genes in pyrethroid-resistant wild Culex quinquefasciatus populations from sub-Himalayan West Bengal, India.

Parasitology research
2025

Uncertainty quantification in cost-effectiveness analysis for stochastic-based infectious disease models: Insights from surveillance on lymphatic filariasis.

Journal of theoretical biology
2025

Lymphatic filariasis: from neglected tropical disease to national priority.

The Lancet. Infectious diseases
2025

Community views on mass drug administration for soil-transmitted helminths: a qualitative evidence synthesis.

The Cochrane database of systematic reviews
2025

The Feasibility of Using Telehealth for Training Health Care Workers and Persons with Disability on Integrated Rehabilitation and Prevention of Impairments and Disabilities of Leprosy, Lymphatic Filariasis, Diabetes, Pressure Ulcers, and Other Chronic Wounds (TeleRPOID Project).

Acta medica Philippina
2025

A Global Systematic Review on the Potential of Metal-Based Nanoparticles in the Fight Against Mosquito Vectors.

Journal of tropical medicine
2025

Community surveys of the prevalence, distribution, and coinfection of helminth and protozoan infections in semiurban and rural areas of Gabon, Central Africa.

PLoS neglected tropical diseases
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Doenças relacionadas

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Emergence of a novel zoonotic brugian filarial infection during post-validation surveillance for lymphatic filariasis in Sri Lanka.
    The Lancet regional health. Southeast Asia· 2026· PMID 41868817mais citado
  2. Cross-sectional study to assess filarial infection among the never treated individuals in selected districts in India: a study protocol.
    BMJ open· 2026· PMID 41856581mais citado
  3. Altitudinal and household breeding patterns of the medically important mosquitoes Aedes aegypti, Aedes albopictus and Culex quinquefasciatus in Nepal.
    PloS one· 2026· PMID 41855226mais citado
  4. Noise and neglect: Social-media signals expose attention gaps for dengue, chikungunya, lymphatic filariasis and kala-azar in India's vector-borne NTDs.
    PLoS neglected tropical diseases· 2026· PMID 41849302mais citado
  5. The impact of the termination of Lymphatic Filariasis mass drug administration on Soil-transmitted Helminth prevalence in school children in Malawi.
    PLoS neglected tropical diseases· 2026· PMID 41739877mais citado
  6. Gene regulation in response to host sex and infection route in Brugia pahangi with new genome annotation.
    G3 (Bethesda)· 2026· PMID 41984800recente
  7. Hotspot-based integrated serosurveillance of neglected tropical diseases, malaria, and vaccine-preventable diseases in urban Guyana.
    Rev Panam Salud Publica· 2026· PMID 41982851recente
  8. Spatiotemporal patterns of climate-sensitive vector-borne diseases in Bangladesh: leveraging machine learning and spatial regression for intervention strategies.
    BMC Med· 2026· PMID 41975424recente
  9. Genetic variations in three insecticide targets in the disease vector Culex quinquefasciatus from Mianyang, China: simultaneous detection of novel mutations RDL A296G and VGSC A1007T.
    Front Cell Infect Microbiol· 2026· PMID 41969656recente
  10. Public-Private Partnership offers a strategic opportunity for Lymphatic Filariasis Elimination in India by 2030.
    Acta Trop· 2026· PMID 41951149recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:2034(Orphanet)
  2. MONDO:0016075(MONDO)
  3. GARD:18757(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Artigo Wikipedia(Wikipedia)
  6. Q815753(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Filariose
Compêndio · Raras BR

Filariose

ORPHA:2034 · MONDO:0016075
Prevalência
Unknown
Herança
Not applicable
CID-10
B74 · Filariose
CID-11
Ensaios
4 ativos
Medicamentos
5 registrados
Início
All ages
Prevalência
0.0 (Europe)
MedGen
UMLS
C0013755
Repurposing
1 candidato
diethylcarbamazinelipoxygenase inhibitor
EuropePMC
Wikidata
Wikipedia
Papers 10a
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