Identification of Bioactive Compounds and Molecular Targets of Compound Herbs Against Stomach Adenocarcinoma: A Network Pharmacology Approach.

Upregulated BLM and RECQL4 in Osteosarcoma: Association with Poor Prognosis, Immune Cell Infiltration, and Inhibitory Effects of Sphingosine Kinase 1 Inhibitor II/Pilaralisib.

Single cell RNA analysis of murine osteosarcoma uncovers Skp2 function in metastasis, genomic instability and immune activation and reveals additional target pathway.

An "off-on" CdTe QDs fluorescent nanosensor for detecting apoptosis in osteosarcoma and evaluating chemotherapy response.

BMSC-derived extracellular vesicles enhance osteosarcoma proliferation and metastasis via the circRNA-0010220/β-catenin pathway.

Treatment paradigms in undifferentiated pleomorphic sarcoma of bone: lessons learned from osteosarcoma and questions that remain commentary on: Bielack SS et al. J Cancer Res Clin Oncol (2026).

Diffusion-weighted imaging of bone and soft tissue tumors: a systematic review.

Osteosarcoma cells promote intracellular iron detoxification to mitigate GPX4-mediated ferroptosis.

Comprehensive analysis of non-tumor lung, liver, and kidney transcriptomes in canine metastatic osteosarcoma.

The first limb-sparing use of histotripsy for canine osteosarcoma.

Vitamin D receptor (VDR) expression in osteosarcoma and its association with histological subtypes and metastasis.

A study of suicide risk and prognostic characteristics in patients with osteosarcoma.

SLC7A5 serves as a potential therapeutic target for osteosarcoma: a comprehensive analysis based on bioinformatics and experimental validation.

Cyclovirobuxine D suppresses cancer stemness in osteosarcoma with implication of the noncanonical NF-kappaB pathway.

Dual-Responsive Micelles Co-delivering All-Trans Retinoic Acid and Paclitaxel for Enhanced Eradication of Osteosarcoma Stem Cells.

The spiral CT imaging characteristics of sarcomatous lesions in the maxillofacial bones: a retrospective analysis.

The cytotoxic effects of glycyrrhizic acid-modified chitosan/selenium nanocomposite on osteosarcoma cancer cell line.

Incorporation of an alpha-hydroxy substituent modulates activity of triazole bisphosphonate-based geranylgeranyl diphosphate synthase inhibitors.

Specific GPCRs elicit unique extracellular vesicle miRNA array signatures.

Deciphering lncRNA and circRNA control of autophagy in osteosarcoma mechanisms and clinical translation.

Extracellular Vesicles in Osteosarcoma: Mechanisms, Diagnostics and Therapeutic Applications.

Glutathione metabolic reprogramming by ferroptosis inducers potentiates cuproptosis and antitumor immunity in osteosarcoma.

Extraskeletal Osteosarcoma of Mediastinal Origin.

Pediatric versus adult cases of primary osseous sarcomas of the spine: A population-based analysis.

Reprogramming CXCL10-mediated NK cell trafficking to enhance immunotherapy in osteosarcoma.

Nobiletin enhances Doxorubicin sensitivity in osteosarcoma through ER stress-induced apoptosis mediated by the PI3K/AKT pathway.

Comprehensive multi-platform tyrosine kinase profiling reveals novel actionable FGFR aberrations across sarcomas affecting the young.

Prognostic role of pretreatment hematologic values and albumin-globulin ratio in canine appendicular osteosarcoma.

Lamins' role in osteosarcoma.

GPRC5B Identified by m5C meRIP-Seq Suppresses Apoptosis in Osteosarcoma Through NSUN2-Mediated RNA Methylation.

Evaluation of the Histopathological Response of Osteosarcoma to Neoadjuvant Chemotherapy by Contrast-Enhanced Ultrasound.

The unphosphorylated, closed form of ezrin binds to RNA to maintain a metastatic phenotype in osteosarcoma cells.

Thymoquinone regulates osteosarcoma cell proliferation through the P53 signaling pathway: A network pharmacology and molecular docking based health technology study.

Endoscopic Debulking in the Management of Osteosarcoma With a Rare Endobronchial Metastasis.

Oncostatin-M ligand-based CAR-T therapy displays robust anti-tumor activity against osteosarcoma.

Paternal exposure to hydrocarbon solvents in the workplace and cancer risk in children and adolescents.

METTL3-mediated m6A modification contributes to anlotinib resistance in osteosarcoma by regulating ferroptosis via the circFAM120B/miR-330-3p/PRKDC axis.

Osteosarcoma is not a single disease: Considerations for multidisciplinary management of jaw (gnathic) osteosarcoma.

RNA-binding Protein NMD3 Promotes Osteosarcoma Cell Proliferation Via Regulating mTOR Signaling Pathway, Exerting Adverse Impacts on Patient Prognosis.

Manganese(i) based NN∩SS bis-chelated homo-binuclear metallacycles: synthesis, spectral, crystallographic, anticancer potential and molecular docking studies.

Activation of α2-adrenergic receptors as a therapeutic strategy for immune rejection in post-surgery osteosarcoma recurrence treatment.

A Case of Grade 2 Radiation‑Induced Osteosarcoma.

CCL5-Mediated Immune Interactions Drive Osteosarcoma Progression: Insights from Mendelian Randomization, Single-Cell Analysis, and Functional Validation.

Deceptive Thyroid Pathologies: Anaplastic Thyroid Carcinoma Mimics and Clinical Implications.

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors.

Analysis of the Relationship Between Survival and Postoperative Infection in Patients With Osteosarcoma.

LARS promotes osteosarcoma proliferation through leucine-dependent PRIM2 translation and DNA replication activation.

A Retrospective Study on the Histological and Clinical Features of 92 Feline Oral Neoplasms in Thailand.

PROTAC-Mediated Targeted Degradation of MDM2 Induces Tumor-Suppressive Signaling in Osteosarcoma Cells.

Isolation and Characterization of Marrow-Isolated Adult Multilineage Inducible (MIAMI) Cell-Derived Extracellular Vesicles Demonstrate Multifunctional Therapeutic Potential in Tissue Regeneration and Anti-Inflammatory Immunomodulation.

Vasculogenic Mimicry: A Potential Therapeutic Target for Chondrosarcoma Therapy.

Pelvic Osteosarcoma: Outcomes of Surgically Treated Patients in a Retrospective Single-Center Study.

Low Survival Rates for Pediatric Patients with Tumor Thrombus in Sarcoma.

Construction and validation of an osteosarcoma prognostic model reveals that SERPINE2 contributes to the progression and cisplatin sensitivity in osteosarcoma.

Corrigendum to "Pulsatilla saponin D inhibited the growth of osteosarcoma by regulating the JNK/ATF3 signaling pathway" [Chem.-Biol. Interact. 410 (2025) 111420].

The ITGB2-COPS3-SOX2 Axis and SOX2 Liquid-Liquid Phase Separation: Dual Mechanisms Governing Osteosarcoma Stemness.

Depleting HIF‑1α attenuates the progression of osteosarcoma, but tumorigenicity is sustained through HIF‑independent pathways.

Advances in Radiation Therapy for Primary Bone Malignancies.

CKS2, regulated by METTL3, contributes to osteosarcoma progression in an IGF2BP1-dependent manner.

Recent advances in biomaterials for osteosarcoma treatment.

Ruptured Uterine Leiomyosarcoma With Heterologous Components Including Osteosarcoma and Chondrosarcoma.

Transcriptome combined with single-cell data to construct a prognostic model for glycosylation-related genes in osteosarcoma.

Aptamers in Osteosarcoma: New Paths for Diagnosis and Treatment.

Case Series of Veterinary Cancer Patients Treated with Oral Low-Dose Naltrexone.

From imaging to omics: deep learning is bridging MRI and liquid biopsy in bone tumor diagnosis.

Curcumin induces apoptosis in osteosarcoma cells by regulating the glycolytic pathway via the MAPK axis: a mechanistic study.

Comprehensive analysis of liquid-liquid phase separation-related genes in osteosarcoma: implications for prognosis, immune infiltration and drug sensitivity.

CNN3 promotes angiogenesis in osteosarcoma, associated with upregulating VEGF-A and enhancing endothelial cell activity.

The roles and pathways of Hsa_circ_0000285 in cancer: a potential target for cancer therapy.

Corrigendum to "Polyethylene microplastics trigger osteosarcoma progression via ITGA5/FAPα/LGMN cancer promoting complex: A novel environmental cancer promoting mechanism" [Ecotoxicol. Environ. Saf. 305 (2025) 119207].

Prognostic and Immunomodulatory Roles of BNIP3 in Osteosarcoma Revealed by Integrated Single-Cell and Bulk Transcriptomic Profiling.

Dynamic wavelet transform normalized multi scale dense attention UNet with Binary Horse Herd Optimization for osteosarcoma diagnosis.

Harnessing a bispecific αGD2 × αCD3 protein engager to target GD2-overexpressing lung tumors.

Research Progress on the Evaluation and Clinical Value of Negative Surgical Margins in Osteosarcoma.

Amino acid metabolism-related genes signature correlates with immune infiltration and predicts clinic prognosis in osteosarcoma.

Narciclasine triggers apoptosis in osteosarcoma cells via JNK-mediated extrinsic and intrinsic pathways.

Effect of Photosensitiser Chlorin E6 on Cancerous Bone Tumor Cells Using Photodynamic Therapy.

Short-interval total femur replacement for infected distal femoral reconstruction.

Allicin inhibits PD-L1 through the IL-6/JAK2/STAT3 pathway to suppress immune evasion in osteosarcoma.

Zoledronic acid-loaded HAp-SiO2-CaMoO4:Eu3+ with luminescent properties as a novel drug delivery system.

Effectiveness of interstitial brachytherapy in extremity sarcoma-treatment outcomes and current concepts.

Fluorinated polymeric nanoplatform relieves tumor hypoxia and enhances chemo-sonodynamic therapy.

Advances in Osteosarcoma Research: Pathogenesis and Emerging Therapeutic Strategies.

Free-ranging Eurasian otter (Lutra lutra) with rare osteoblastic osteosarcoma: a forensic and genetic investigation from central Italy.

Multifunctional nanoplatforms deciphering immune resistance in bone tumors: cooperative delivery, immune reprogramming and microenvironment remodeling.

Clinical, radiographic and histopathological analysis of bone-forming tumors of the oral and maxillofacial region: A 53-year retrospective study.

Effective high-dose methotrexate toxicity reversal using fixed-dose glucarpidase in obese patients: a case series.

Macrophage-centered immunotherapy for osteosarcoma: mechanisms, repolarization, and translational strategies.

Long-term clinical remission in rapidly recurrent maxillary osteosarcoma treated with anlotinib-based multimodal therapy: a case report.

Treatment outcomes and prognosis of osteosarcoma in patients aged 9 years or younger: A study using the nationwide bone tumor registry in Japan.

Targeting signaling cascades by bioactive phytocompounds in osteosarcoma: A novel therapeutic approach.

Clarification on the interpretation of TCGA-SARC data in the prognostic evaluation of MMP13 in osteosarcoma.

MISTOSUS: a phase II trial of Viscum album extract adjuvant therapy for relapsed resectable osteosarcoma.

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis.

Inhibition of Autophagy Reveals ATR Protein Kinase as a Key Mediator of Cisplatin Sensitivity in Osteosarcoma.

Matrix micro/nano-topography drives oncogenic signaling and drug response in a 3D osteosarcoma model.

Risk factors for pulmonary metastases in osteosarcoma: a systematic review and meta-analysis.

S100A13 transcriptionally activated by SP1 facilitates osteosarcoma metastasis.

Multifunctional hybrid chitosan/κ-carrageenan sponges integrating engineered SBA-15@Fe3O4 composites and nano-hydroxyapatite for bone tissue engineering.

Synthesis of Limonia acidissima gum-based biopolymer/samarium substituted hydroxyapatite biocomposite for bone tissue engineering applications.

Trends in Long-Term Excess Mortality Risk and Survival Among Childhood and Adolescent Cancer Survivors in the United States.

Histone deacetylases: Function in tumor development and therapeutic prospects (Review).

Ginkgetin targets GRP78 to induce dual pathways of ER stress and immune activation in osteosarcoma.

Losartan, toceranib, and carboplatin combination therapy for progressive pulmonary metastasis in canine osteosarcoma: a case report.

Maternally Expressed Gene 3 (MEG3) LncRNA: The silent guardian against solid and hematological malignancies.

CAR-T cell therapy for pediatric solid tumors: armored CAR-T cells and beyond.

Efficacy analysis and survival prediction of unique chemotherapy regimens for osteosarcoma in China.

Case Report: Complete response to the concurrent neoadjuvant radiation therapy and pembrolizumab in a locally recurrent, chemotherapy-refractory undifferentiated pleomorphic sarcoma of bone.

The Role of DNA Methylation in Osteosarcoma Pathogenesis and Therapy.

Development and evaluation of an inhalable nanoemulsion system for enhancing NK cell function against osteosarcoma pulmonary metastases.

Imaging interorganelle membrane contact sites using dimerization-dependent fluorescent proteins.

Reconstruction of T cell infiltration in an osteosarcoma PDX-organoid interactive biobank for personalized immunotherapy.

Targeting the metabolic fingerprint of amino acids to identify novel metabolic characteristics in osteosarcoma patients undergoing anthracycline treatment.

Chondromyxoid Fibroma: An Updated Review.

Methionine Restriction Alone Induces T-cell-mediated Immunotherapy of Osteosarcoma in a Syngeneic Mouse Model.

SMARCAL1 is a candidate therapeutic target for ALT-positive tumors.

Non-invasive MRI biomarkers for assessment of neoadjuvant chemotherapy response in osteosarcoma: Current techniques and clinical perspectives.

Cytotoxic and Cytostatic Effects of Nanoformulated Fenretinide on MG63 Osteosarcoma Cells.

Comprehensive Investigation of a Novel Schiff Base: Synthesis, Anticancer Efficacy, Gene Expression Profiling, and Computational Analyses.

Overall Survival and Prognostic Factors in Osteosarcoma: A Nationwide Cohort Study from Taiwan.

Catharanthus roseus Extract-Loaded Zn-Substituted Hydroxyapatite Nanocomposites as a Multifunctional Antioxidant and Anticancer Therapeutic Applications.

Age-Stratified Transcriptomic Profiling Reveals Biologically Distinct Molecular Phenotypes Across Pediatric, Adolescent, and Adult Osteosarcoma.

Antitumor Effects of PD-1 Blockade Combined with Mild Hyperthermia in a Murine Osteosarcoma Model.

The Interplay Between Bone Biology and Iron Metabolism: Molecular Mechanisms and Clinical Implications.

Antimetastatic Effects of a Griffonia simplicifolia Seed Extract in Osteosarcoma Cell Lines.

Cyclo-(His-Phe) Complexes with Copper and Zinc Nanoparticles Have Antimicrobial Properties and Targeted Anticancer Potential Against Osteosarcoma Cells.

Prognostic Analysis of Endoprosthetic Reconstruction Versus Biological Reconstruction in the Treatment of Extremity Osteosarcoma.

Calcineurin Homologous Protein 2 Acts as a Conditional Modulator of Migration and Proliferation in Human Bone Sarcoma Cells.

From Bench to Bedside: Advancements in Precision Oncology and Drug Discovery for Osteosarcoma.

Limb-Salvage Reconstruction of the Proximal Humerus Using Patient-Specific 3D-Printed PEEK Implants: A Midterm Clinical Study.

Physical Activity in Osteosarcoma Patients During and Post Therapy: A Single Site Prospective Observational Study.

Visualization analysis of the use of traditional Chinese medicine in the diagnosis and treatment of rare diseases in mainland China based on CiteSpace.

Bio-inks with PRF Increase Human Osteosarcoma Cell Line (SaOS-2) Viability in Extrusion-Based 3D-Bioprinted Constructs.

In vitro modeling of nutritional and mitochondria-targeted therapies for osteosarcoma.

Epidemiology of Four Major Canine Tumours in the UK: Insights From a National Pathology Registry With Comparative Oncology Perspectives.

Ultrasound-responsive bone-targeting liposomes suppress osteosarcoma through enhanced ROS generation and immunogenic cell death.

PCMTD1-127aa suppresses osteosarcoma progression by competitively binding to USP10 to promote c-MYC degradation.

Development and verification of a comprehensive diagnostic model for osteosarcoma using random forest and artificial neural network.

Internalized stigma among pediatric patients with osteosarcoma and retinoblastoma in Guatemala, Jordan, and Zimbabwe.

Advances in T cell-based immunotherapy for osteosarcoma.

Eutectic Mixture Approach for Enhancing Solubility, Permeability, and Bioactivity of Curcumin: Influence of Ferulic Acid and Nicotinamide as Coformers.

Nanoparticles Targeting the Tumor Microenvironment for the Treatment of Osteosarcoma: Recent Progress and Perspectives.

sB7-H3 as a prognostic biomarker in osteosarcoma: insights into clinical outcomes.

Third-degree atrioventricular block from metastatic poorly differentiated sarcoma suggestive of osteosarcoma in a dog.

Consensus recommendations in the management of jaw (gnathic) osteosarcoma.

Network pharmacology reveals that Yanghe Decoction inhibits osteosarcoma progression via ROS-induced mitochondrial dysfunction and enhances cisplatin sensitivity.

Skeletal stem cell lineages in osteosarcoma and bone metastasis.

Construction of an Immunogenic Cell Death-Related Long Non-Coding RNA Signature for Predicting Prognosis in Osteosarcoma.

Efficacy, safety and cost-effectiveness of CAR-T therapy.

Malignant transformation of fibrous dysplasia in long bones: a clinicopathological and molecular study of 19 cases.

Differential expression of CD74 and C1QB in jaw versus long bone osteosarcoma: Insights from animal models, public datasets and clinical cohorts.

pH-Responsive Nanoparticle-Coated Calcium Phosphate Granules for Bone Cancer Therapy.

HSP90AB1-Mediated Ubiquitin-Proteasome Degradation of ITGBL1 Promotes Osteosarcoma Progression by Inhibiting Endoplasmic Reticulum Stress-Induced Autophagy.

Casuistry of oncological diseases in dogs, focusing on bone tumors treated at the Veterinary Hospital of the University of the Republic, Uruguay (2018-2023).

NPM1 phosphorylation-mediated telomere maintenance via stabilization of POLD3 in ALT-positive osteosarcoma: unraveling mechanisms and therapeutic opportunities.

Establishment of a m6A-Related Molecular Pattern in the Prognosis and Immune Infiltration of Osteosarcoma Using Machine Learning and Experiments.

Diethyl Phthalate (DEP) as a potential osteosarcoma risk factor: a multi-omics study integrating network Toxicology, single-cell RNA sequencing, and molecular docking.

Real-World Experience of Efficacy and Tolerability of Continuous Infusion Ifosfamide for Advanced Soft Tissue and Bone Sarcoma Patients: A Single Centre Retrospective Cohort.

Intratumor heterogeneity and clonal evolution in sarcomas: Molecular, cellular, and functional drivers of therapy resistance.

Spinal extradural meningioma mimicking lumbar disc herniation in a cat: a case report.

NSUN6-mediated m5C RNA methylation aggravate osteosarcoma progression through promoting PKP2 mRNA stability and expression.

Liquid biopsy in malignant primary bone tumors: Clinical applications of circulating tumor DNA and circulating tumor cells for diagnosis, prognosis and treatment monitoring (Review).

Role of SPAG6 in regulating physiological functions and tumorigenesis (Review).

A machine learning-driven prognostic model based on peripheral blood lymphocyte subsets in osteosarcoma.

Glutathione-responsive deformable manganese-based nanomedicines for enhanced tumor-specific chemotherapy.

A Putative Hsa-miR-582-5p-CD81 Relationship Identified by Integrative Transcriptomic Analysis in Osteosarcoma.

Identification of Key Bioactive Compounds of Medicine-Food Homologous Substances and Their Multi-Target Intervention Effects in Osteosarcoma Treatment.

A Dangerous Region Generation Method for Computer-Assisted Pelvic Bone Tumor Resection Surgery: A Retrospective Study.

A Systematic Review of Cutaneous Involvement in Metastatic Bone Sarcomas: Insights from 102 Reported Cases.

Immune Infiltration Landscape in Osteosarcoma: Clinical Implications for Prognosis and Therapy.

CHD4 epigenetically coordinates genomic instability and immunosuppression to drive pan-cancer progression and confer HDAC inhibitor sensitivity.

Unaltered NKG2D-CAR T cell function under hypoxia in osteosarcoma in vitro.

APOE suppresses osteosarcoma by modulating ferroptosis through the mTOR/Stat3 signaling pathway.

Pneumonectomy for an endobronchial carcinosarcoma with long-term survival: a case report.

HeartWare™ HVAD support without anticoagulation.

MnOx-armored magnesium implants for anti-osteosarcoma and biofilm eradication by charge-transfer interference.

Optimized data augmentation for osteosarcoma detection in deep and lightweight networks.

Development and verification of a competing risk model for forecasting cancer-specific survival in malignant bone tumor patients: an analysis of SEER database.

MicroRNA-374b-5p suppresses osteosarcoma progression via the PDPK1-mediated AKT pathway.

The Reliability of Measuring Muscle Cross-Sectional Area in Children Undergoing Treatment for Musculoskeletal Sarcoma.

Primary Meningeal Extraskeletal Osteosarcoma in a Domestic Shorthaired Cat: Case Report and Review of Comparative Pathology.

5-hydroxymethylcytosine profiles in circulating cell-free DNA associate with disease status in patients with osteosarcoma.

Analysis of prognostic factors related to pulmonary metastasectomy for hepatocellular carcinoma following liver resection.

Single photon emission computed tomography/computed tomography clue to pulmonary metastasis in osteosarcoma: a diagnostic pitfall of technetium-99m methylene diphosphonate uptake.

Evaluation of Germline Pathogenic Variant of TP53 Gene in an Iranian Pedigree with Familial Sarcoma: A Case Report.

Separation Methods Affect Glycan Patterns in Extracellular Vesicle Preparations From Canine Osteoblasts and Osteosarcoma Cells.

Harnessing natural compounds and nanotechnology for miRNA-based osteosarcoma therapy.

Gemcitabine-docetaxel therapy in pediatric patients with relapsed or refractory sarcoma: a single-center experience.

Epidemiology and Prognosis of Patients With Osteosarcoma at Different Primary Sites: A SEER Population-Based Study.

Natural compounds in the treatment of osteosarcoma: just chemotherapy adjuvants? or is there much more?

A LDH-Based Supramolecular Photosensitizer-Functionalized Bioactive Glass Scaffold for Integrated Postoperative Osteosarcoma Recurrence Prevention and Bone Regeneration.

Stage at Diagnosis and International Survival Variation in Childhood Tumors in the BENCHISTA Study.

A polymeric triple-enzyme nanoparticle by light activatable crosslinking for cascade catalytic therapy of osteosarcoma.

Carcinosarcoma of the Parotid With Osteosarcoma Component: A Case Report.

Excision of proximal fibular aggressive and malignant tumors: a new classification for surgical guidance.